Medicine and Health Sciences Commons^™

Prognostic Effect Of Glycated Hemoglobin In Acute Myocardial Infarction, Mohamad El Bordy, Nadia Youssef Riad

Journal of Medicine in Scientific Research

Background Impaired glucose tolerance and even prediabetic states have a crucial role as risk factors among several different risk factors in acute myocardial infarction (AMI). Some recent studies have shown that poor diabetes management, diagnosed by glycated hemoglobin (HbA1C), has poor prognostic value regarding future cardiovascular events, whereas other studies recommend that it is the blood glucose level at admission that predicts short-term mortality after AMI and not the HbA1C level. Aim The target of this research is to detect the correlation between the level of HbA1C and risk factors in the patients with AMI and its value regarding the …

Predictors Of Mortality Among Egyptian Hemodialysis Patients With Coronavirus Disease 2019: A Multicenter Retrospective Cohort, Amany A. Salem, Enass E. El-Sayed, Hala M. Abd-Elmaguid, K Allayeh Abdou, Mona Abd Elmotaleb A. Hussein, Muhammed M. Abdul-Ghaffar, Omnia S. Ali, Sheren M. Omar, Wael M. Essa

Journal of Medicine in Scientific Research

Background With a diagnostic problem, the emerging severe acute respiratory syndrome coronavirus 2 caused a devastating global consequence. We were identifying severity/mortality risk variables that assist in determining the need for early admission. As a result, we sought to establish for the first time the clinical, biochemical, and radiological characteristics of coronavirus disease 2019 (COVID-19) in Egyptian hemodialysis patients and to identify the risk factors for mortality. Patients and methods In this observational multicenter retrospective cohort study in Egypt, the data of 377 confirmed COVID-19 patients on regular hemodialysis were collected from hospitals affiliated to the general organization of teaching …

Lower-Limb Resistive Versus Aerobic Training Impact On Quality Of Life In Post-Covid-19 Patients, Asmaa M. Mohamed, Elsaeed E. Shaaban, Esraa A. Mohamed, Zahra M. H. Serry

Journal of Medicine in Scientific Research

Objective To determine the effect of lower-limb resistive versus aerobic training impact on quality of life (QOL) in post-COVID-19 patients. Participants and methods Sixty young volunteer patients participated in this study and randomly divided into two equal groups: group A that received an aerobic exercise program three times per week, group B, which received lower-body-resistance exercises. Both groups were evaluated before and after therapy (6 weeks) through measuring resting heart rate (RHR), peak heart rate (PHR), neutrophil/lymphocyte ratio, one-repetition maximum (1-RM) of selected muscle groups, and QOL assessment using the Short-Form (SF-12) Health Survey Questionnaire. Results The results revealed a …

Assessment Of Auditory Dysfunction As An Extra-Articular Manifestation In Rheumatoid Arthritis Using Brainstem Auditory-Evoked Potential, Abeer H. Ismaiel, Ahmad M. A. Gawad, Amany F. Hakim, Soha S. Shaaban

Journal of Medicine in Scientific Research

Objectives The paper aims to study brainstem auditory-evoked potential parameter changes in rheumatoid arthritis (RA) patients, and their relation to the duration of illness, degree of disease activity, functional stage of the disease, and intensity of pain. Materials and methods Control (group 1) comprised 25 healthy female patients of age 50–60 years, while the study group (group 2) comprised 25 female patients with RA of more than 5 years. Proven cases of RA (according to american college of rheumatology (ACR) 2010 criteria) underwent brainstem auditory-evoked potentials. The recording was carried out by using RMS EMG EPMK2. In the RA group, …

Posterior Tympanotomy Versus Posterior Atticotomy In Creating Well-Ventilated Middle Ear Cleft Pros And Cons, Essam F. Abdelfattah, Wael A. Alzami

Journal of Medicine in Scientific Research

Background Cortical mastoidectomy is considered a cornerstone step in the surgical management of noncholesteatomatous chronic suppurative otitis media. It comprises the canal wall-up technique, preserving the posterior and superior bony canal walls. The goal of cortical mastoidectomy is mainly to ventilate the middle ear cleft besides eradication of diseased mastoid air cells. The ventilation of the middle ear cleft has no way except through the aditus ad antrum and patent epitympanic diaphragm besides well-functioning Eustachian tube. This way of ventilation is usually affected in chronic infected ears by edematous and polypoid mucosa, leading to its obstruction. Traditional practice used to …

Prediction Of Cardiac Surgery-Associated Acute Kidney Injury Using Cleveland And Mehta Scores, Maged M. A. Kisho

Journal of Medicine in Scientific Research

Objective To detect the clinical accuracy of two models for the prediction of cardiac surgery-associated acute kidney injury (AKI) and severe AKI that need renal replacement therapy according to Cleveland and Mehta scores and using Kidney Disease Improving Global Outcomes (KDIGO) definitions for AKI. Patients and methods In total, 742 patients who underwent cardiac surgery in the Department of Cardiac Surgery NHI of Egypt, between January 2016 and December 2018, were enrolled in this research. We evaluate the prediction for cardiac surgery-associated AKI using Cleveland and Mehta scores. We also evaluate the effect of hemofiltration during cardiopulmonary bypass as a …

Predictors Of Left Ventricular Systolic Dysfunction After Primary Percutaneous Coronary Intervention For Patients With Left Anterior Descending Artery Occlusion, Ahmed Galal A Fattah Fahmy, Mohamed E. L Bordy

Journal of Medicine in Scientific Research

Background Depressed left ventricular (LV) systolic function after acute coronary syndrome is the most important predictor affecting morbidity and mortality. The primary objective of reperfusion therapy is to restore epicardial flow and to reperfuse the myocardial tissue. However, not all the patients show improvement, and a group of patients may experience depression in heart function. Aim To determine the factors affecting impairment of LV function assessed by echocardiography following successful primary percutaneous coronary intervention (PCI) in patients with acute coronary syndrome involving the left anterior descending (LAD) artery. Patients and methods A total of 50 patients were included in this …

Metabolic Syndrome And Asthma, Therese S. Ghatas

Journal of Medicine in Scientific Research

Introduction Bronchial asthma is one of the chronic diseases that most commonly present worldwide. Asthma is still a poorly controlled disease despite the availability and intake of medications in a large percentage of asthmatic patients. Research studies are indicated to identify the effect of metabolic syndrome on the occurrence of asthma and its severity and also to clear the underlying important mechanisms. Patients and methods This cross-section study was carried out on 108 patients with asthma. Asthma was diagnosed and classify according to Global Initiative for Asthma guideline. All asthmatic patients were tested for the criteria of metabolic syndrome. Aim …

Health-Related Quality Of Life In Children And Adolescents With Chronic Kidney Diseases At Sohag, Egypt: A Case–Control Study, Ahmed M. Hegab, Eman Abdel-Baset Mohamed, Fouad M. A. Yousef, Rasha Gamal-El-Din Abu-El-Goud

Journal of Medicine in Scientific Research

Background and objectives Chronic kidney diseases (CKD) have multiple complications that could impair the quality of life in the affected children and their families. This study aimed to assess the health-related quality of life (HRQOL) and detect factors affecting it in children with CKD and their families at Sohag, Egypt. Patients and methods The study included 113 children and adolescents with CKD stages 1–5, aged 2–18 years old, attending the pediatric nephrology outpatient clinic and the pediatric dialysis unit at Sohag University Hospital. Two hundred twenty-six children were in the control-group age and sex matched to cases with urinary-system condition …

The Effect Of Cervical Spondylosis On Diaphragmatic Thickness And Excursion In Nonsmoking Adults, Akram A. Elaziz, Bishoy G. Khalil, Saif Mehmed, Tamer A. El-Kassas

Journal of Medicine in Scientific Research

Background Cervical spondylosis is defined as a series of signs and symptoms that result in anatomical and physiological changes in the vertebral column that may impair phrenic nerve function by compressing the C3/C5 that affect diaphragmatic movements. Purpose The purpose of this study was to investigate the effect of cervical spondylosis on diaphragmatic thickness and excursion in nonsmoking adults by using ultrasonographic evaluation of the diaphragm. Eighty-four nonsmoking volunteers participated in this study and were divided into two equal groups: group A, patients with cervical spondylosis and group B, healthy volunteers with a normal cervical spine. Both groups were evaluated …

Effectiveness Of Ultrasound-Guided Platelets Rich Plasma Injection In Knee Osteoarthritic Cases, Abeer N. A. Aziz, Gamal S.E E. Khalifa, Hesham Alshabrawy, Lamis Safwat

Journal of Medicine in Scientific Research

Backgroud Knee osteoarthritis is the most common articular disease. Different methods are used to alleviate the symptoms of patients with knee osteoarthritis, including analgesics, physical therapy, exercise prescription, and intra-articular injections (glucocorticoids, hyaluronic acid). New studies have focused on modern therapeutic methods that stimulate the cartilage healing process and improve the damage, including the use of platelet-rich plasma as a complex growth factor. Aim of the work To evaluate the effectiveness of intra articular PRP in mild to moderate degree knee osteoarthritis. Objectives To slow the rate of progression of knee Osteoarthritis by injection of PRP intraarticular. Decrease pain and …

Relationship Between Chronic Obstructive Pulmonary Disease And Helicobacter Pylori Infection, Moheb W. Elfaizy, Therese S. Ghatas

Journal of Medicine in Scientific Research

Introduction There are insignificant observations and few research studies that indicate the action of Helicobacter pylori in the induction of extra-gastrointestinal tract diseases, which include autoimmune, skin, and vascular diseases, and also some pulmonary diseases. Moreover, it has been documented that the incidence of chronic bronchitis may be elevated in patients who experienced H. pylori infection. Aim To assess infection with H. pylori in patients with chronic obstructive pulmonary disease (COPD) and in control persons and also to determine the association between serology level of H. pylori and spirometry parameters in patients experiencing COPD. Results A total of 100 individuals …

The Role Of Postoperative Imaging In Cochlear Implants, Essam F. Mohammed

Journal of Medicine in Scientific Research

Objective The aim was to evaluate the role and efficacy of high-resolution computed tomography (CT) scan after cochlear implantation in evaluating the integrity and insertion of the electrode, whether complete or incomplete, whether intracochlear or extracochlear, and whether to change the decision for revision or not. Sitting The study was conducted at the Hearing and Speech Institute. Patients and methods All the patients 300 cases undergo CT scan radiology within one week postoeratively and reevaluated for electrode insertion. Complete, incomplete, or over insertion. intracochlear or extracchlear. Results This study was carried out on 312 cases from January 2019 to December …

Patient–Valve Mismatch: A Comparison Of Mechanical Versus Biological Prostheses In Ischemic Mitral Patients Undergoing Chordal-Sparing Mitral Valve Replacement, Ahmed S. Ali, Rania D.E A. Shokka, Rasha H. Mohammed

Journal of Medicine in Scientific Research

Background Chordal-sparing mitral valve replacement (MVR) is now preferred over downsized annuloplasty repair in treating chronic severe ischemic mitral regurgitation. However, total leaflet preservation carries the risk of patient–valve mismatch (PVM). The authors aimed to investigate the incidence of PVM among those groups of patients who were treated with either mechanical or biological MVR. Objective This study aimed to compare the incidence of PVM in ischemic mitral regurgitation patients undergoing total revascularization together with chordal-sparing MVR with either biological or mechanical prosthesis. Patients and methods A controlled prospective study was carried out at the National Heart Institute Cairo, Egypt. 50 …

Processing Binding Data Using An Open-Source Workflow, Errol L G Samuel, Secondra L Holmes, Damian W Young

Faculty, Staff and Students Publications

The thermal shift assay (TSA)—also known as differential scanning fluorimetry (DSF), thermofluor, and Tm shift—is one of the most popular biophysical screening techniques used in fragment-based ligand discovery (FBLD) to detect protein–ligand interactions. By comparing the thermal stability of a target protein in the presence and absence of a ligand, potential binders can be identified. The technique is easy to set up, has low protein consumption, and can be run on most real-time polymerase chain reaction (PCR) instruments. While data analysis is straightforward in principle, it becomes cumbersome and time-consuming when the screens involve multiple 96- or 384-well plates. There …

Beyond The Raskin Protocol: Ketamine, Lidocaine, And Other Therapies For Refractory Chronic Migraine., Jeffrey J. Mojica, Eric S. Schwenk, Clinton Lauritsen, Stephanie J. Nahas

Department of Anesthesiology Faculty Papers

PURPOSE OF REVIEW: The purpose of this review is to discuss the available evidence and therapeutic considerations for intravenous drug therapy for refractory chronic migraine.

RECENT FINDINGS: In carefully monitored settings, the inpatient administration of intravenous lidocaine and ketamine can be successful in treating refractory chronic migraine. Many patients with refractory chronic migraine have experienced treatment failure with the Raskin protocol. The use of aggressive inpatient infusion therapy consisting of intravenous lidocaine or ketamine, along with other adjunctive medications, has become increasingly common for these patients when all other treatments have failed. There is a clear need for prospective studies …

A Multilayer Network Model Of The Coevolution Of The Spread Of A Disease And Competing Opinions, Kaiyan Peng, Zheng Lu, Vanessa Lin, Michael R. Lindstrom, Christian Parkinson, Chuntian Wang, Andrea L. Bertozzi, Mason A. Porter

School of Mathematical & Statistical Sciences Faculty Publications

During the COVID-19 pandemic, conflicting opinions on physical distancing swept across social media, affecting both human behavior and the spread of COVID-19. Inspired by such phenomena, we construct a two-layer multiplex network for the coupled spread of a disease and conflicting opinions. We model each process as a contagion. On one layer, we consider the concurrent evolution of two opinions — pro-physical-distancing and anti-physical-distancing — that compete with each other and have mutual immunity to each other. The disease evolves on the other layer, and individuals are less likely (respectively, more likely) to become infected when they adopt the pro-physical-distancing …

Activation Of The Α1Β2Γ2l Gaba Receptor By Physiological Agonists, Spencer R Pierce, Allison L Germann, Gustav Akk

Open Access Publications

The Cl

Access Barriers To Telehealth, Quynh Chau, Amita Behuria Pathak, Daniel Turner, Jacquelyn Cheun, Carl Noe

SMU Data Science Review

Abstract. Telehealth has long been touted as an efficient and cost-effective way to deliver health care services to patients. The COVID-19 global pandemic hastened the adoption of this technology in the United States. Despite its promises, telehealth as a technology-based model of health service delivery has also highlighted access to care inequities in the form of uneven utilization across various patient demographics. This research uses machine learning and publicly available data sources to describe telehealth utilization based on social determinants of care. The implications of this application can be used to inform health care providers of how to target efforts …

Clinical Diagnosis Support With Convolutional Neural Network By Transfer Learning, Spencer Fogleman, Jeremy Otsap, Sangrae Cho

SMU Data Science Review

Breast cancer is prevalent among women in the United States. Breast cancer screening is standard but requires a radiologist to review screening images to make a diagnosis. Diagnosis through the traditional screening method of mammography currently has an accuracy of about 78% for women of all ages and demographics. A more recent and precise technique called Digital Breast Tomosynthesis (DBT) has shown to be more promising but is less well studied. A machine learning model trained on DBT images has the potential to increase the success of identifying breast cancer and reduce the time it takes to diagnose a patient, …

Machine Learning Approach To Distinguish Ulcerative Colitis And Crohn’S Disease Using Smote (Synthetic Minority Oversampling Technique) Methods, Kris Ghimire, Walter Lai, Yasser Omar, Thad Schwebke, Jamie Vo

SMU Data Science Review

Irritable Bowel Disease (IBD) affects a sizable portion of the US population, causing symptoms such as vomiting, abdominal pain, and diarrhea. Despite the disease’s prevalence, the precise cause is not fully understood. This study consists of endoscopic and histological data from patients diagnosed with IBD and a control population for reference. The machine learning models' focus is to classify patients into IBD types. Several models were analyzed, including decision trees, logistic regression, and k-nearest neighbors. In addition, various methods of SMOTE were applied to determine the most effective transformation and ensuring that the dataset is balanced. The best model with …

Practice Development Trajectories Of Experienced Nurses: Adaptive Experts, Routine Experts, And Non-Experts, Dee Mulcahy

Nursing ETDs

This qualitative study examined practice development among experienced, acute care nurses (n = 9) with at least 10 years of experience. Using an interpretive biographical approach, with participants’ written practice narratives and in-depth interviews, the study focused on how the work environment and life experiences influenced or impeded practice development. Participants were classified as routine- or adaptive experts (n = 3 of each type) with one intermediate case and two not readily classifiable. Antecedents to becoming a nurse included family influences, personal interests, altruistic values, and financial need. Experience was necessary but not sufficient for adaptive expertise. Compared …

Role Of School-Based Occupational Therapy Practitioners: Perspectives From Teachers And Ots, Kristen A. Ollison, Pam Kasyan-Howe, Kristin Domville, Lisa Schubert

Fall 2021 Virtual OTD Capstone Symposium

Schools are the third largest employer of occupational therapists (OTs) in the United States (U.S. Bureau of Labor Statistics, 2021). Occupational Therapists have the distinctive ability to observe the child in their natural context of the school, a place where children participate in a variety of activities (Benson et al., 2015). The problem is that there continues to be discrepancies in the understanding and utilization of OT services in the school setting that affect the perceptions of both OTs and teachers regarding the OT role in school, and general service provision (Bolton & Plattner, 2020; Seruya & Garfinkel, 2020; Truong …

Culture Change For Occupational Therapists On Safe Patient Handling And Mobility (Sphm): Advocacy For Sphm Policies For A National Organization., Guldana Alizakhova, Pam Kasyan-Howe, Kristin Domville, Lisa Schubert

Fall 2021 Virtual OTD Capstone Symposium

Safe patient handling and mobility is an ergonomic approach consisting of policies, programs, and equipment to reduce WMSD and facilitate a culture of safety among patients and healthcare practitioners. Due to occupational therapy’s established role in ergonomics, practitioners are skilled to utilize SPHM to provide evaluative, consultative, preventative, and therapeutic services to patients while preventing WMSDs to healthcare practitioners. Despite OT’s contributions to SPHM, occupational therapy practitioners are not recognized as leaders in SPHM. To address this problem, in the Spring 2021 meeting, the AOTA Representative Assembly was presented a request for action by a taskforce that also recognized this …

Kris Brickman, M.D. Interview For The Boonshoft School Of Medicine 50th Anniversary Oral History Project, Kris Brickman, Kristen Dilger

Boonshoft 50th Anniversary Oral History Project

Kristen Dilger interviews Kirs Brickman, a graduate of the Boonshoft School of Medicine and Chief Physician Executive at the University of Toledo at the time of the interview. Part of the class of 1983, Brickman discusses his collegiate career, including why he chose Wright State University's new medical college and talks about what it was like attending the college. He talks about the challenges and processes of attending a new medical college, and how attending the Wright State University Boonshoft School of Medicine assisted him in his early career.

Healthcare Associated Infections: A Benchmark Study, Neal Ziedan

MSN Capstone Projects

When it comes to hospital-acquired infections, whether the hospital has implemented best-practice infection control measures, whether it has introduced best practice infection control measures, or whether it will be held vicariously liable for negligent or intentional failures by staff to follow the infection control measures in place, is the determining factor. If a hospital and its administrators fail to develop or implement best practice infection control methods, resulting in patient harm, they may be held directly liable. Patients may be held vicariously liable if hospital employees fail to comply with infection control measures implemented by the hospital during the course …

2021-12-10_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

2021-12-10_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated three times a week on Mondays, Wednesdays and Fridays.

Syndromic Surveillance System data is obtained from approximately 216 facilities participating in syndromic surveillance (139 Emergency Departments (ED), 77 Urgent Care) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, …

2021-12-10 Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

2021-12-10_Michiganoverview_Covidvaccinestats, Michigan Department Of Health & Human Services

Michigan COVID-19 Vaccine Data

The COVID Vaccine Dashboard page was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus/0,9753,7-406-98178_103214-547150--,00.html.

First-dose tracker above is for entire Michigan Population. Coverage maps below are for age 5+.

Previously reported numbers of administered vaccine doses may change as new data are received. A possible lag in reporting vaccine doses will result in increases in numbers previously reported.

This report is created by the Michigan Department of Health and Human Services Division of Immunization from data reported to the Michigan Care Improvement Registry (MCIR).

The dashboard contained the tabs Vaccines Delivered, Delivery Trend, Primary Series Doses Administered, …