Medicine and Health Sciences Commons^™

Njohuritë E Infermierëve Për Depresionin, Shkëlzen Niko

Theses and Dissertations

Qëllimi kryesor i këtij hulumtimi është vlerësimi në dallimet e njohjes dhe qëndrimeve të infermierëve ndaj të të sëmurëve depresivë. Çdo ditë e më shumë janë duke u shtuar rastet e personave me depresion dhe thuja se është duke u bërë shkaktari më i madh i vetëvrasjeve. Gjithashtu, qëllimi i këtij punimi është hulumtimi i shkallës së njohurive të infermiereve dhe i gatishmerise dhe qasjes së tyre ndaj pacientëve me depresion meqë ata duhet të trajtohen me kohë, të marrin terapinë e duhur, kujdesi infermieror të jetë sa më i mirë dhe i përkushtuar ndaj tyre, si dhe të japim …

Trauma-Informed Care, Heather Forkey, Moira Szilagyi, Erin T. Kelly, James Duffee, Sarah H. Springer, Moira Szilagyi, Heather Forkey, Kristine Fortin, Mary Booth Vaden Greiner, Todd J. Ochs, Anu N. Partap, Linda Davidson Sagor, Deborah L. Shropshire, Jonathan D. Thackeray, Douglas Waite, Lisa Weber Zetley

Pediatrics Faculty Publications

No abstract provided.

Standardizing New Diagnostic Tests To Facilitate Rapid Responses To The Covid-19 Pandemic, Xiao Dong

Dissertations and Theses (Open Access)

In order to enhance the data interoperability, an expeditious and accurate standardization solution is highly desirable for naming rapidly emerging novel lab tests, and thus diminishes confusion in early responses to pandemic outbreaks. This is a preliminary study to explore the roles and implementation of medical informatics technology, especially natural language processing and ontology methods, in standardizing information about emerging lab tests during a pandemic, thereby facilitating rapid responses to the pandemic. The ultimate goal of this study is to develop an informatics framework for rapid standardization of lab testing names during a pandemic to better prepare for future public …

Biomarkers For Impending Risk Of Osteoporosis In Premenopausal Women, Rehana Rehman, Ali Usman, Aisha Sheikh, Rozeena Baig

Department of Biological & Biomedical Sciences

Objective: To compare 'cytokines' and 'bone turnover markers' in pre- and post-menopausal women and identify their relationship with bone mineral density (BMD) in both groups. Study Design: A cross-sectional study.
Place and duration of study: Department of Biological & Biomedical Sciences, The Aga Khan University, Karachi, Pakistan, from June 2017 to August 2019.
Methodology: Groups comprised of healthy premenopausal and postmenopausal women from the general population belonging to different ethnic groups and socio-economic status. Serum cytokines and bone turnover markers were assessed by solid-phase immunoassays, BMD (gm /cm2)] measurement was performed by dual-energy X-ray absorptiometry at the hip, lumbar spine, …

Frequency Of Primiparous Mother Initiated Breastfeeding Earlier After Birth And Factors Associated With It In Sindh, Pakistan: A Secondary Analysis, Asma A. Bham, Sucheta Sharma, Akash Sardool, Umer F. Mujahid, Amrat Ayaz, Komal Valliani, Nawaal Maredia

Community Health Sciences

Background: Initiation of breastfeeding within one hour after delivery plays a vital role in a newborns life by not only increasing their survival rate but also reducing many life-threatening diseases in the newborn. The aim of the study was to determine frequency of early initiation of breastfeeding among primiparous mothers in a rural district of Thatta, Pakistan.
Methods: This study was conducted using survey data extracted from a cross-sectional study conducted in 2019 on prevalence of exclusive breastfeeding and factors associated with it among women in Thatta. The outcome was early initiation of breastfeeding. To determine factors associated with it, …

Kajian Hubungan Antara Iklim Keselamatan Psikososial (Psychosocial Safety Climate) Dengan Perundungan Di Tempat Kerja (Workplace Bullying) Di Pt Wid, Ika Wahyuningtias, Dadan Erwandi, Sjahrul Meizar Nasri, Abdul Kadir

National Journal of Occupational Health and Safety

This study aims to examine and analyze the correlation and influence of Psychosocial Safety Climate on the occurrence of workplace bullying at PT WID (a power generation company) involving six power plant work areas across Indonesia. Methods: This research employed a cross-sectional study design involving 100 workers from the Operational & Maintenance business line who were aged above 17 years and had a minimum of six months of work experience. Participants were asked to complete the Psychosocial Safety Climate (PSC-12) questionnaire to measure the level of psychosocial safety climate and the Negative Acts Questionnaire-Revised (NAQ-R) to determine the level of …

Hubungan Antara Iklim Keselamatan Dengan Perilaku Keselamatan Pada Pekerja Proyek Pln Pusmapro Pst Jateng I, Charisha Kumala, Doni Hikmat Hikmat Ramdhan

National Journal of Occupational Health and Safety

Background: A safety management system is essential for implementation in the construction industry to manage safety at project sites. The sustainability of the running system can be assessed by analyzing the relationship between safety climate and safety behavior without having to wait for an accident to occur. Objective: To analyze the relationship between safety climate and safety behavior among workers at PLN PUSMANPRO in the PST JATENG I electrical construction project. Methods: This cross-sectional study involved 120 workers at the PLN PUSMANPRO PST JATENG I Project. Primary data were obtained using a Likert scale questionnaire that referred to questionnaires …

Syndrome Of Inappropriate Antidiuretic Hormone Secretion And Lead Toxicity In A Child With Sickle Cell Disease And Pica., Akshay Gupta Do, Alexandra Amaducci Do, Andrew L. Koons, John D. Lindmark, Gillian A. Beauchamp Md

Department of Emergency Medicine

We describe the presentation and management of a three-year-old child with a history of pica, vitamin D deficiency, and sickle cell disease, who was admitted for pyelonephritis, and found to have elevated blood lead level (BLL) of 103.7 µg/dL, and who subsequently developed altered mental status and syndrome of inappropriate antidiuretic hormone secretion (SIADH). In consultation with Medical Toxicology, the patient was chelated with calcium disodium edetate (EDTA) and British Anti Lewisite (BAL). The patient's hyponatremia was managed with hypertonic saline infusion. The patient's encephalopathy improved throughout her hospital course, and she was discharged on hospital day 8. Following five …

Assessment Of Emergency Medicine Resident Performance In A Pediatric In Situ Simulation Using Multi-Source Feedback., Michael C Nguyen, Nicole C Elliott, Diane P Begany, Katie M Best, Matthew D Cook, Michael R Jong, Zachary M Matuzsan, Louis A Morolla, Suzanne S Partington, Bryan G Kane

Department of Emergency Medicine

Introduction Multi-source feedback (MSF) is an evaluation method mandated by the Accreditation Council for Graduate Medical Education (ACGME). The Queen's Simulation Assessment Tool (QSAT) has been validated as being able to distinguish between resident performances in a simulation setting. The QSAT has also been demonstrated to have excellent MSF agreement when used in an adult simulation performed in a simulation lab. Using the QSAT, this study sought to determine the degree of agreement of MSF in a single pediatric (Peds) simulation case conducted in situ in a Peds emergency department (ED). Methods This Institutional Review Board-approved study was conducted in …

The Ability And Safety Of Community-Based Health Workers To Safely Initiate Lifesaving Therapies For Pre-Eclampsia In Ogun State, Nigeria: An Analysis Of 260 Community Treatments With Mgso4 And/Or Methyldopa, Akinmade A. Adepoju, Marianne Vidler, Adebayo A. Akadri, Ebun Jaiyesimi, Chimaobi C. Nwankpa, Oluwafayokemi O. Odubena, Sumedha Sharma, Larry Li, Domena Tu, Zulfiqar Ahmed Bhutta

Woman and Child Health

Objectives: To evaluate community-based health workers' ability to identify cases of hypertension in pregnancy, safely deliver methyldopa and magnesium sulphate and make referrals when appropriate.
Study design: This was part of Nigeria Community-Level Interventions for Pre-eclampsia (CLIP) cluster randomized controlled trial (NCT01911494). Community-based Health Workers (CHW) recruited pregnant women from five Local Government Areas (clusters) and used mobile health aid for clinical assessment of pre-eclampsia.
Main outcome measures: The primary outcome was the number of adverse events that occurred after the administration of magnesium sulphate and/or methyldopa to pregnant women by CHWs.
Findings: Of 8790 women receiving mobile …

Application Of The Ultra-Poverty Graduation Model In Understanding Community Health Volunteers’ Preferences For Socio-Economic Empowerment Strategies To Enhance Retention: A Qualitative Study In Kilifi, Kenya, Njeri Nyanja, Nelson Nyamu, Lucy Nyaga, Sophie Chabeda, Adelaide Lusambili, Marleen Temmerman, Michaela Mantel, Anthony Ngugi

Family Medicine, East Africa

Background: A significant shortage of healthcare workforce exists globally. To achieve Universal Healthcare cover- age, governments need to enhance their community-based health programmes. Community health volunteers (CHVs) are essential personnel in achieving this objective. However, their ability to earn a livelihood is compromised by the voluntary nature of their work; hence, the high attrition rates from community-based health programmes. There is an urgent need to support CHVs become economically self-reliant. We report here on the application of the Ultra-Poverty Graduation (UPG) Model to map CHVs’ preferences for socio-economic empowerment strategies that could enhance their retention in a rural area …

Barriers To Timely Disclosure Of Hiv Serostatus: A Qualitative Study At Care And Treatment Centers In Dar Es Salaam, Tanzania, Neelam Ismail, Nancy Matillya, Riaz Ratansi, Columba Mbekenga

Family Medicine, East Africa

Introduction: Disclosure of Human Immunodeficiency Virus (HIV) status is important to prevent the spread of HIV and maintain the health of people living with HIV, their spouses, and the community. Despite the benefits of disclosure, many people living with HIV delay disclosing their status to those close to them thereby increasing the risk for disease transmission. This study aimed to determine the barriers to timely disclosure of HIV serostatus for people living with HIV in Dar es Salaam, Tanzania, and identify what motivated disclosure.

Methods: A qualitative descriptive study using in-depth individual interviews was conducted with10 participants attending …

Investir Dans Le Changement Social Et Comportemental Est Rentable Pour Améliorer Les Comportements Antipaludiques En Côte D’Ivoire, Breakthrough Research

Sexual and Reproductive Health, Rights, and Choices

Social and behavior change (SBC) interventions are considered an essential part of malaria prevention and treatment interventions, yet gaps in information on the cost and impact of SBC mean decisionmakers have underappreciated the value of SBC for contributing to improved health outcomes. To address this issue, Breakthrough RESEARCH has leveraged evidence from 112 studies on the impact of SBC interventions on malaria health behaviors and 70 studies on general SBC intervention costs to model the cost-effectiveness of SBC programming for malaria in the Business Case for Investing in Social and Behavior Change for Malaria.

Molecular Differences In Skeletal Muscle After 1 Week Of Active Vs. Passive Recovery From High-Volume Resistance Training, Christopher G. Vann, Cody T. Haun, Shelby C. Osbourn, Matthew E. Romero, Paul A. Roberson, Petey W. Mumford, C. Brooks Mobley, Hudson M. Holmes, Carlton D. Fox, Kaelin C. Young, Michael D. Roberts

Faculty Scholarship

Numerous studies have evaluated how deloading after resistance training (RT) affects strength and power outcomes. However, the molecular adaptations that occur after deload periods remain understudied. Trained, college-aged men (n = 30) performed 6 weeks of whole-body RT starting at 10 sets of 10 repetitions per exercise per week and finishing at 32 sets of 10 repetitions per exercise per week. After this period, subjects performed either active (AR; n = 16) or passive recovery (PR; n = 14) for 1 week where AR completed ∼15% of the week 6 training volume and PR ceased training. Variables related to …

Alcohol Use In Women: Resources And Recommendations For Counselors, Samantha Haling

Educational Specialist, 2020-current

The research shows that alcohol use is rising rapidly among women, resulting in devastating consequences that have not been sufficiently explored in counselor education and training. This paper aims to address this by providing a review of the literature which shows that women are more vulnerable to many of the physical and mental health consequences of alcohol use than men, and that they have unique treatment needs and face gender-specific risk factors and barriers to treatment. The review examines the interaction between gender and alcohol use, summarizes the existing research on the physical and behavioral health consequences of alcohol use …

Lambda-Cyhalothrin Used As An Insecticide In Agriculture: Study Of Biomarker Toxicokinetics To Monitor Worker Exposure, Michèle Bouchard, Jonathan Côté, Rania Khemiri

Rapports de recherche scientifique

Les insecticides pyréthrinoïdes sont une famille de pesticides largement utilisés au Québec pour lutter contre les insectes nuisibles dans les cultures maraîchères. Parmi ces insecticides, on compte la lambda-cyhalothrine. Malgré l’utilisation abondante de ce pyréthrinoïde, il existe peu de données sur le comportement biologique de cette molécule chez l’humain. Il devient donc essentiel de développer des outils pour bien évaluer l’exposition des travailleurs à ces pesticides lors d’épandages ou de travaux dans des zones traitées. La surveillance biologique, par la mesure de produits excrétés dans l’urine (appelés métabolites), est considérée comme une approche privilégiée pour évaluer les doses réellement absorbées …

Delayed First Bath, Yesenia Diaz Adn, Rn, Olivia Jimenez Bsn, Rn, Jasmine Mailler Bsn, Rn

Vizient/ AACN Nurse Residency Program™ EBP Projects

No abstract provided.

Investigation Of Postmortem Methamphetamine Cases Submitted To The New York City Office Of Chief Medical Examiner, Isaiah Jewell

Student Theses

Methamphetamine (N-methylamphetamine) is a central nervous system stimulant (CNS) and sympathomimetic drug with a high addiction potential. In the United States, there has been a significant increase in the presence of methamphetamine in recent years, specifically in the Northeastern region of the country. The New York City Office of Chief Medical Examiner (NYC-OCME) postmortem methamphetamine casework from 2018 and 2019 was analyzed and revealed that the presence of the drug increased drastically within a span of one year, jumping from 65 cases in 2018 to 99 cases in 2019. Males were overwhelmingly responsible for much of the casework, taking up …

Dean's Research Newsletter, August 2021, Jerry L. Nadler

SOM Dean's Research Newsletter

No abstract provided.

In Situ Chromatin Interaction Analysis Using Paired-End Tag Sequencing., Ping Wang, Yuliang Feng, Kun Zhu, Haoxi Chai, Ya-Ting Chang, Xiaofei Yang, Xiyuan Liu, Chen Shen, Eva Gega, Byoungkoo Lee, Minji Kim, Xiaoan Ruan, Yijun Ruan

Faculty Research 2021

Chromatin Interaction Analysis Using Paired-End Tag Sequencing (ChIA-PET) is an established method to map protein-mediated chromatin interactions. A limitation, however, is that it requires a hundred million cells per experiment, which hampers its broad application in biomedical research, particularly in studies in which it is impractical to obtain a large number of cells from rare samples. To reduce the required input cell number while retaining high data quality, we developed an in situ ChIA-PET protocol, which requires as few as 1 million cells. Here, we describe detailed step-by-step procedures for performing in situ ChIA-PET from cultured cells, including both an …

The Prevalence Of Albuminuria In Children With Chronic Kidney Disease In Two Tertiary Hospitals In Nairobi, Kenya, Mercy Wambui Githumbi

Master of Medicine in Paediatrics and Child Health

Background: Chronic kidney disease (CKD) is a major health problem globally. In Africa, the burden in children remains unclear and is often reported as low. In developing countries, it is mainly due to secondary causes and nephrotic syndrome, while in the developed countries it is mainly due to congenital anomalies of kidney and urinary tract (CAKUT). The Kidney Disease: Improving Global Outcomes (KDIGO) defines CKD and utilises glomerular filtration rate (GFR) and albuminuria as an additional factor. Albuminuria is significant in prognostication of individuals with CKD as it is a marker of kidney damage. It is correlated with outcomes including …

Red Blood Cell Transfusion In Critically-Ill Children And Its Association With Outcome, Hafsa Sohail, Shah Ali Ahmed, Parveen Usman, Farah Khalid, Anwar Ul Haque, Qalab Abbas

Department of Emergency Medicine

Objective: To determine the indications and threshold of haemoglobin levels for packed red blood cell transfusion and its association with outcomes in a paediatric intensive care setting.
Methods: The retrospective study was conducted in the paediatric intensive care unit of the Aga Khan University Hospital, Karachi, and comprised medical records of all inpatients with age between 1 month and 16 years who received packed red blood cell transfusions between January and December 2017. Data was retrieved from the hospital database and was analyzed using SPSS 22.
Results: Of the 147 subjects with a mean age of 67.89±65.8 months, 76(51.7%) were …

“I Want Justice From People Who Did Bad Things To Children”: Experiences Of Justice For Sex Trafficking Survivors, John G. Morrissey, James Havey, Glenn M. Miles, Nhanh Channtha, Lim Vanntheary

Dignity: A Journal of Analysis of Exploitation and Violence

This research from the Butterfly Longitudinal Research Project focused on understanding the experiences and perceptions of justice and the justice system for 93 Cambodia participants (including 88 survivors of sex trafficking) as they navigated the legal system. Thirty-two of these survivors had experiences in court and provided details into their courtroom experiences, predominantly within Cambodia but also in the United States. The survivors’ experiences were diverse; however, the prevailing themes were: fear throughout their legal journeys; a low level of awareness and understanding of their legal experiences; and that NGO support was essential for these survivors to engage in the …

"Going It Alone": Following The Male Cohort Of Survivors Of Sex Trafficking Of The Chab Dai Butterfly Longitudinal Research Project, Jarrett D. Davis, James Havey, Glenn M. Miles, Nhanh Channtha, Sreang Phally, Lim Vanntheary

Dignity: A Journal of Analysis of Exploitation and Violence

Over the past ten years, the Butterfly Longitudinal Research Project has followed 128 survivors of trafficking through their experiences in aftercare, reintegration, and beyond to better understand the recovery and reintegration of trafficking survivors within a Cambodian context. This paper focuses on the 19 males who were available to interview. Despite the project’s wealth of data and analysis, there are notable gaps regarding the male cohort. In response, this paper examines this cohort holistically, considering their statements and broader narratives, merging them with previous collective observations of the Butterfly Project. Throughout this paper, data indicates a pattern of violence among …

School Police Reform: A Public Health Imperative, Thalia González, Emma Kaeser

SMU Law Review Forum

Out of the twin pandemics currently gripping the United States­—deaths of unarmed Black victims at the hands of police and racialized health inequities resulting from COVID-19—an antiracist health equity agenda has emerged that identifies racism as a public health crisis. Likewise, calls for reform of school policing by those advocating for civil rights, racial justice, and Black Lives Matter have simultaneously intensified. Yet each remains siloed, despite the natural connection and implicit overlap between these separate movements and debates. Indeed, there are documented negative health effects of school policing for Black, Indigenous, people of color (BIPOC) youth. But these have …

Innovative Computational Methods For Pharmaceutical Problem Solving A Review Part Ii: Serious Gaming, Heather R. Campbell, Robert A. Lodder

Pharmaceutical Sciences Faculty Publications

Serious gaming has begun to take a foothold in pharmaceutical problem-solving. Companies such as Akili's Interactive are seeing success in the form of positive clinical trial results and FDA approval of digital therapeutics. Academic researchers have begun exploring novel uses for serious gaming in the way of protein design and more with promising results. This paper provides a review of such topics in addition to topics of game repurposing- repurposing a game originally intended for entertainment into a serious game-such as Minecraft and America's Army. Reviewing these topics this paper shows the utility of serious gaming as a tool for …

Innovative Computational Methods For Pharmaceutical Problem Solving A Review Part I: The Drug Development Process, Heather R. Campbell, Robert A. Lodder

Pharmaceutical Sciences Faculty Publications

Computational methods have provided pharmaceutical scientists and engineers a means to go beyond what's possible with experimental testing alone. Providing a means to study active pharmaceutical ingredients (API), excipients, and drug interactions at or near-atomic levels. This paper provides a review of this and other innovative computational methods used for solving pharmaceutical problems throughout the drug development process. Part one of two this paper will emphasize the role of computational methods and game theory in solving pharmaceutical challenges.

Trauma-Informed, Integrated Primary Care: A Medical Home Model For Children With Prenatal Drug Exposure Who Enter Foster Care, Jill Mcleigh, Hilda Loria, Kelsey Craker, Susanna Bird

Integrated, Trauma-Informed Care

The rise in prenatal or childhood substance exposure diagnoses resulting from parental substance use has led to an increase in the number of children placed in foster care. Meeting the multifaceted health care needs of children with prenatal drug exposure (PDE) who enter foster care requires significant time, resources, and coordination. In addition to conditions resulting from their experiences of trauma, children in foster care often have unmet health care needs and experience disproportionate rates of adverse physical, mental and developmental health outcomes. This article outlines the barriers to providing comprehensive and high-quality care to this pediatric population and …

Telehealth Assessment In The Elderly Using The 4m'S, Witeh Esoe

Nursing Capstones

COVID-19 brought unprecedented challenges in accessing healthcare services. The lack of accessibility to healthcare drastically impacted older adults, especially those in rural America, who experienced multiple issues accessing quality care with an increase in healthcare cost leading to a significant increase in morbidity and mortality rate from COVID-19. Consequently, the usage of telehealth services skyrocketed during the pandemic. As a result, the Geriatric Workforce Enhancement Program (GWEP) emerged with the aim to promote the use of telehealth services to reduce COVID-19 exposure to older adults in rural North Dakota (ND). Thereby keeping older adults safe at home and still having …

Perceptions Of Surgeons On Surgical Antibiotic Prophylaxis Use At An Urban Tertiary Hospital In Tanzania, Elizabeth Mmari, Eunice Pallangyo, Authar Ali, Dereck A. Kaale, Isaac Mawalla, Muzdalfat Abeid

General Surgery, East Africa

Background: Surgical Site Infections are a major cause of morbidity and mortality among operated patients. In spite of the accessibility of universal and national guidelines for surgical prophylaxis, recent studies surveying the present routine of prophylaxis have demonstrated overutilization of a wide range antibacterial medication for a single patient. Few studies have shown qualitatively factors influencing this and perceptions of surgeons on surgical antibiotic prophylaxis use. Unfortunately, none of these studies have been done in Tanzania.

Objective: To describe the perceptions of surgeons on surgical antibiotic prophylaxis use at an urban tertiary hospital.

Methods: A qualitative study …