Medicine and Health Sciences Commons^™

2021-10-18_Michiganoverview_Covidcounts, Michigan Department Of Health & Human Services

Michigan COVID-19 Confirmed Cases by Date of Onset Data

Data was downloaded as an Excel spreadsheet which appeared in the Public Use Datasets section under the Cumulative Data link of Michigan's Coronavirus webpage, under the url https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173---,00.html.

Cases are aggregated by the date of onset of COVID-19 symptoms, if known, otherwise by laboratory specimen date if known, otherwise by case referral date. Deaths are aggregated by the date of death if known, otherwise by the last date of a change to the case status.

Genetic Differences In Dorsal Hippocampus Acetylcholinesterase Activity Predict Contextual Fear Learning Across Inbred Mouse Strains., Sean M Mooney-Leber, Dana Zeid, Prescilla Garcia-Trevizo, Laurel R Seemiller, Molly A. Bogue, Stephen C. Grubb, Gary Peltz, Thomas J Gould

Faculty Research 2021

Learning is a critical behavioral process that is influenced by many neurobiological systems. We and others have reported that acetylcholinergic signaling plays a vital role in learning capabilities, and it is especially important for contextual fear learning. Since cholinergic signaling is affected by genetic background, we examined the genetic relationship between activity levels of acetylcholinesterase (AChE), the primary enzyme involved in the acetylcholine metabolism, and learning using a panel of 20 inbred mouse strains. We measured conditioned fear behavior and AChE activity in the dorsal hippocampus, ventral hippocampus, and cerebellum. Acetylcholinesterase activity varied among inbred mouse strains in all three …

Attributes And Characteristics Of The Physician-Physician Assistant Organizational Leader Relationship, Victoria S. Louwagie

Graduate Dissertations and Theses

Purpose: The aim of this study was to evaluate and better understand the attributes and characteristics of the influential physician, the dual-roled physician assistant (PA)leader and how this relationship impacts the PA leader and the PA leader-physician relationship. These dual-role PA leaders may possess additional formal job titles and duties while also having direct reports.

Method: We surveyed PA leaders at a large academic medical center and its associated health system. The survey instrument evaluates perceptions, attitudes and characteristics of the PA leader, influential physician, and their relationship.

Results: There were 34/56 PA organizational leaders that responded to the survey …

A Rollout Of A Blood Pressure Remote Patient Monitoring Program To Improve High-Risk Maternal Outcomes At A Pilot Clinic For Systemwide Expansion, Laura Geron

Seton Hall University Dissertations and Theses (ETDs)

An existing virtual care platform provides an innovative means of early recognition, identification, and intervention for women with elevated blood pressures during pregnancy, known as preeclampsia. A pilot program took place at a Northeastern prenatal care clinic where patients were identified as high-risk for preeclampsia, enrolled, educated by their providers, and equipped with Bluetooth-enabled blood pressure cuffs.

Through remote patient monitoring (RPM) technology, blood pressure readings could transmit from a patient’s residence to a portal accessible by their clinic provider at any time. This doctoral-level quality improvement project focuses on the identification of patients at high-risk for preeclampsia, their enrollment …

A Telephone-Adapted Mindfulness-Based Stress Reduction Program: Preliminary Effects Among Healthcare Employees, Lauren A Zimmaro, Aleeze Sattar Moss, Diane K. Reibel, Elizabeth A Handorf, Jennifer B Reese, Carolyn Y Fang

Marcus Institute of Integrative Health Faculty Papers

Healthcare employees often experience high stress and may benefit from accessible psychosocial interventions. In this pilot study, we explored preliminary feasibility, acceptability, and psychological effects of a telephone-based adaption of mindfulness-based stress reduction (MBSR) for healthcare employees. Eleven participants (M age = 49.9; 27.3% ethnic/racial minority) were enrolled in an eight-session group-based MBSR program adapted for telephone delivery. Feasibility was assessed using rates of program attrition and session completion; acceptability was explored qualitatively via participants' responses to an open-ended item about their program experience. Participants also completed pre-and post-program assessments on psychosocial outcomes (distress (overall distress, depression, anxiety, somatization), mindfulness, …

Dna Methylation-Calling Tools For Oxford Nanopore Sequencing: A Survey And Human Epigenome-Wide Evaluation., Yang Liu, Wojciech Rosikiewicz, Ziwei Pan, Nathaniel L. Jillette, Ping Wang, Aziz Taghbalout, Jonathan Foox, Christopher Mason, Martin Carroll, Albert Cheng, Sheng Li

Faculty Research 2021

BACKGROUND: Nanopore long-read sequencing technology greatly expands the capacity of long-range, single-molecule DNA-modification detection. A growing number of analytical tools have been developed to detect DNA methylation from nanopore sequencing reads. Here, we assess the performance of different methylation-calling tools to provide a systematic evaluation to guide researchers performing human epigenome-wide studies.

RESULTS: We compare seven analytic tools for detecting DNA methylation from nanopore long-read sequencing data generated from human natural DNA at a whole-genome scale. We evaluate the per-read and per-site performance of CpG methylation prediction across different genomic contexts, CpG site coverage, and computational resources consumed by each …

Fusion Versus Fixation In Complex Comminuted C3-Type Tibial Pilon Fractures: A Systematic Review., Yash P Chaudhry, Efstratios Papadelis, Hunter Hayes, Philip F Stahel, Erik A Hasenboehler

Orthopedic Surgery Resident Research

BACKGROUND: Comminuted intra-articular tibial pilon fractures can be challenging to manage, with high revision rates and poor functional outcomes. This study reviewed [1] treatment, complications, and clinical outcomes in studies of complex comminuted tibial pilon fractures (type AO43-C3); and [2] primary ankle arthrodesis as a management option for these types of complex injuries.

METHODS: A systematic literature search was performed on PubMed from 1990 to 2020 to determine complications and outcomes after staged fracture fixation and primary ankle joint arthrodesis for comminuted C3-type tibial pilon fractures. The search was conducted in compliance with the PRISMA guidelines, using the following MeSH …

Prescribers' Satisfaction With Delivering Medications For Opioid Use Disorder, Hannah K. Knudsen, Randy Brown, Nora Jacobson, Julie Horst, Jee-Seon Kim, Hanna Kim, Lynn M. Madden, Eric Haram, Todd Molfenter

Behavioral Science Faculty Publications

BACKGROUND: Expanding access to medications for opioid use disorder (MOUD), such as buprenorphine and extended release (XR) naltrexone, is critical to addressing the US opioid epidemic, but little is known about prescriber satisfaction with delivering these two types of MOUD. The current study describes the satisfaction of prescribers delivering buprenorphine and XR-naltrexone while examining whether satisfaction is associated with current patient census and organizational environment.

METHODS: As part of a cluster randomized clinical trial (RCT) focused on expanding access to medication for opioid use disorder, 41 MOUD prescribers in Florida, Ohio, and Wisconsin completed a web-based survey. The survey included …

Intouch October 18, 2021, New York Medical

InTouch

• NYMC Center of Excellence in Precision Responses to Bioterrorism and Disasters Receives $250,000 in Funding
• Graduate Student Association Welcomes New Slate of Officers After Going One Year Completely Virtual
• NYMC and TCUS Host 15th COVID-19 Symposium
• Department Spotlight: The Office of Student Financial Planning Uses Decades of Experience to Help NYMC Students

2021-10-18_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

Nsaids Naproxen, Ibuprofen, Salicylate, And Aspirin Inhibit Trpm7 Channels By Cytosolic Acidification, Rikki Chokshi, Orville Bennett, Tetyana Zhelay, J. Ashot Kozak

Neuroscience, Cell Biology & Physiology Faculty Publications

Non-steroidal anti-inflammatory drugs (NSAIDs) are used for relieving pain and inflammation accompanying numerous disease states. The primary therapeutic mechanism of these widely used drugs is the inhibition of cyclooxygenase 1 and 2 (COX1, 2) enzymes that catalyze the conversion of arachidonic acid into prostaglandins. At higher doses, NSAIDs are used for prevention of certain types of cancer and as experimental treatments for Alzheimer’s disease. In the immune system, various NSAIDs have been reported to influence neutrophil function and lymphocyte proliferation, and affect ion channels and cellular calcium homeostasis. Transient receptor potential melastatin 7 (TRPM7) cation channels are highly expressed in …

On The Road To Accreditation For Ambulatory Health Care- A College Health Center Quality Assurance And Improvement Program, Kathleen Hynes-Lifland

Seton Hall University Dissertations and Theses (ETDs)

The time has come for figureheads in higher education to address and strengthen Quality Assurance (QA) and Quality Improvement (QI) in college health. Goals and objectives should be designed to pursue better care and health. Quality Assurance (QA) strives to guarantee that health care providers are adhering to their policies, procedures, and protocols. Compliance may be monitored by intermittent audits, peer review activities, and inspections. QA answers the question, “are we meeting the standards?” This project attempted to provide these standards through the development of a QA/QI policy and procedure which reflects ideologies set forth by the Accreditation Association for …

Incorporating Emergency Management Training Within School-Based Health Centers, Alicia Christian

Seton Hall University Dissertations and Theses (ETDs)

Background: Emergencies are situations that present without warning but require skilled individuals to provide aid to someone needing assistance. The pediatric primary care setting rarely experiences emergency-based care, which could lead to a lack of training in this area of expertise. As pediatric primary care extends to schools, there is also a need to ensure staff and providers have an annual emergency management training program. Project Aim: The current program aimed to determine the need to incorporate emergency management training in the school-based health center (SBHC) setting. Methods: This quality improvement project method was a pre-intervention with post-intervention design. The …

Evaluation Of Telemedicine As An Option For Providing Safe, Accessible, Care To Young Adults In A University Setting, Diane Lynch

Seton Hall University Dissertations and Theses (ETDs)

Previously underutilized, telemedicine has been implemented within a wide variety of health settings as a safe and efficient way of delivering healthcare during the COVID-19 pandemic. Maintaining operations during the pandemic made implementation of telemedicine an important aspect of college and university health center reopening plans. The purpose of this project was to evaluate the acceptance and quality of a telemedicine program implemented at the health center of a medium sized private university.

Data were collected via patient and staff surveys to measure satisfaction with the program and a retrospective review of electronic medical records was conducted to obtain data …

The Creation Of A Template For The Incorporation Of A Human Milk Analyzer Into A Human Milk Bank, Sarah Rieber

Seton Hall University Dissertations and Theses (ETDs)

Abstract

A milk bank is a nonprofit service that collects, screens, and processes by pasteurization human milk that is donated by mothers not biologically related to the infant in need. Milk is then dispensed to hospitals and private homes to babies with a prescription. A milk bank collects and analyzes human milk, as breast milk is the ideal nutrition source and the gold standard feeding method for infants. Breast milk significantly reduces premature babies' chance of developing necrotizing enterocolitis (NEC) and offers gastrointestinal protection, increases immunity, decreases the likelihood of asthma, allergies, ear infections, obesity, and respiratory ailments. Some mothers …

Promotion Of Heart Failure Self-Care In The Outpatient Setting, Meredith C. Lubas

Seton Hall University Dissertations and Theses (ETDs)

Medical management of chronic heart failure consists of a closely managed medication regimen, cardiovascular testing, interventions, and lifestyle modification, including self-care practices. While medication management, testing, and interventions have concrete guidelines, heart failure self-care education lacks solid guidelines and thus is often poorly defined and variable in practice. Outpatient heart failure treatment typically focuses on medication management more than self-care practices. This project addresses the current lack of heart failure self-care education in the outpatient setting.

For this project, a total of seven patients with heart failure with a reduced ejection fraction received a patient survey in order to assess …

Debriefing With Pearls & Watson’S Caritas, Heather A. Uccello

Seton Hall University Dissertations and Theses (ETDs)

Debriefing, an important aspect of students’ clinical experience, is a reflective, critical thinking analysis and communication strategy that provides rapid feedback after either a simulated or genuine clinical event. To teach this higher-level critical thinking skill throughout the learning process, nursing programs require specific methodology and faculty expertise. The National League for Nursing supports nurse educators having a theory-based strategy, formal training, and ongoing competency evaluation. Informed by Jean Watson’s Theory and the Promoting Excellence and Reflective Learning in Simulation standardized debriefing tool methodology, this project outlines a framework that nursing schools can use to potentially improve the debriefing process …

Social Anxiety Screening And Associated Factors Among University Students, Kathleen Prendergast

Seton Hall University Dissertations and Theses (ETDs)

Social anxiety is a type of anxiety triggered by social situations whereby the individual feels scrutinized by others, and which may contribute to avoidance of certain situations. This avoidance can interfere with personal, academic, and career endeavors. Cognitive behavioral therapy can help manage social anxiety. However, social anxiety is often underrecognized and
under treated. A survey with the Liebowitz Social Anxiety Scale (LSAS) was disseminated to identify and address this need among students in a large Northeastern university in the United States. The study is valuable as a pilot study. There was a small response rate for participation in the …

Paro As A Biofeedback Medical Device For Mental Health In The Covid-19 Era, Takanori Shibata, Lillian Hung, Sandra Petersen, Kate Darling, Kaoru Inoue, Katharine Martyn, Yoko Hori, Geoffrey Lane, Davis Park, Ruth Mizoguchi, Chihiro Takano, Sarah Harper, George W. Leeson, Joseph F. Coughlin

Nursing Faculty Publications and Presentations

The COVID-19 pandemic is spreading across the globe, and it could take years for society to fully recover. Personal protective equipment (PPE), various hygiene measures, and social distancing have been implemented to reduce "human to human" contact, which is an essential part of outbreak prevention. The pressure of the pandemic combined with decreased communication and social contact have taken a toll on the mental health of many individuals, especially with respect to anxiety and depression. Effective use of robots and technology as a substitute for--or in coordination with--traditional medicine could play a valuable role in reducing psychological distress now more …

Multiple-Brain Systems Dynamically Interact During Tonic And Phasic States To Support Language Integrity In Temporal Lobe Epilepsy, Shilpi Modi, Xiaosong He, Kapil Chaudhary, Walter Hinds, Andrew Crow, Ashithkumar Beloor-Suresh, Michael R Sperling, Joseph I Tracy

Department of Neurology Faculty Papers

An epileptogenic focus in the dominant temporal lobe can result in the reorganization of language systems in order to compensate for compromised functions. We studied the compensatory reorganization of language in the setting of left temporal lobe epilepsy (TLE), taking into account the interaction of language (L) with key non-language (NL) networks such as dorsal attention (DAN), fronto-parietal (FPN) and cingulo-opercular (COpN), with these systems providing cognitive resources helpful for successful language performance. We applied tools from dynamic network neuroscience to functional MRI data collected from 23 TLE patients and 23 matched healthy controls during the resting state (RS) and …

Electroencephalography In Patients With Autism Spectrum Disorder, A A Asadi-Pooya

Department of Neurology Faculty Papers

No abstract provided.

Spinal Cord Signal Change On Magnetic Resonance Imaging May Predict Worse Clinical In- And Outpatient Outcomes In Patients With Spinal Cord Injury: A Prospective Multicenter Study In 459 Patients., Thorsten Jentzsch, David W Cadotte, Jefferson R Wilson, Fan Jiang, Jetan H Badhiwala, Muhammad A Akbar, Brett Rocos, Robert G Grossman, Bizhan Aarabi, James Harrop, Michael G Fehlings

Department of Orthopaedic Surgery Faculty Papers

Prognostic factors for clinical outcome after spinal cord (SC) injury (SCI) are limited but important in patient management and education. There is a lack of evidence regarding magnetic resonance imaging (MRI) and clinical outcomes in SCI patients. Therefore, we aimed to investigate whether baseline MRI features predicted the clinical course of the disease. This study is an ancillary to the prospective North American Clinical Trials Network (NACTN) registry. Patients were enrolled from 2005-2017. MRI within 72 h of injury and a minimum follow-up of one year were available for 459 patients. Patients with American Spinal Injury Association impairment scale (AIS) …

Refining A Postpandemic Approach To Cancer Screening, Michael A. Thompson

Journal of Patient-Centered Research and Reviews

In introducing Volume 8, Issue 4 of Journal of Patient-Centered Research and Reviews — a specially themed issue comprised of several works focused on improving cancer screening processes in clinical practice — JPCRR editor and hematologist/oncologist Michael Thompson reflects on the current state of various screening modalities and how the pandemic has already begun to shape ongoing research in this area. A delicate balance must be struck between avoiding overtesting or overdiagnosis and identifying the presence of malignant tumors early enough to allow for successful treatment.

Communication Skills Training: A Means To Promote Time-Efficient Patient-Centered Communication In Clinical Practice, Else Dalsgaard Iversen, Maiken Wolderslund, Poul-Erik Kofoed, Pål Gulbrandsen, Helle Poulsen, Søren Cold, Jette Ammentorp

Journal of Patient-Centered Research and Reviews

Purpose: We hypothesized that health care providers would behave in a more patient-centered manner after the implementation of communication skills training, without causing the consultation to last longer.

Methods: This study was part of the large-scale implementation of a communication skills training program called "Clear-Cut Communication With Patients" at Lillebaelt Hospital in Denmark. Audio recordings from real-life consultations were collected in a pre-post design, with health care providers' participation in communication skills training as the intervention. The training was based on the Calgary-Cambridge Guide, and audio recordings were rated using the Observation Scheme-12.

Results: Health care providers improved their communication …

Patient Perceptions Of Using Clinical Decision Support For Cancer Screening And Prevention: “I Wouldn’T Have Thought About Getting Screened Without It.”, Daniel M. Saman, Melissa L. Harry, Laura A. Freitag, Clayton I. Allen, Patrick J. O'Connor, Joann M. Sperl-Hillen, Joseph A. Bianco, Anjali R. Truitt, Heidi L. Ekstrom, Thomas E. Elliott

Journal of Patient-Centered Research and Reviews

Purpose: We sought to gain an understanding of cancer prevention and screening perspectives among patients exposed to a clinical decision support (CDS) tool because they were due or overdue for certain cancer screenings or prevention.

Methods: Semi-structured qualitative interviews were conducted with 37 adult patients due or overdue for cancer prevention services in 10 primary care clinics within the same health system. Data were thematically segmented and coded using qualitative content analysis.

Results: We identified three themes: 1) The CDS tool had more strengths than weaknesses, with areas for improvement; 2) Many facilitators and barriers to cancer prevention and screening …

Integrating Telemedicine Services In Ophthalmology: Evaluating Patient Interest And Perceived Benefits, Eric Shiuey, Yehuda Fox, Adam Kurnick, Rony Rachmiel, Shimon Kurtz, Michael Waisbourd

Department of Medicine Faculty Papers

Purpose: The purpose of this study was to assess patient interest and willingness to pay (WTP) for teleophthalmology services, whose benefits include improved healthcare access and potential cost savings.

Patients and methods: Cross-sectional study of 215 patients attending a single tertiary center to assess their interest in teleophthalmology. Comparisons between those interested and those not interested were conducted; logistic regression was used to evaluate the effect of price on interest.

Results: Two thirds (66.5%) of patients were interested in teleophthalmology instead of in-person clinic visits. Those interested were significantly younger than uninterested patients (48.8±22.7 vs 62.4±18.3 years) and were more …

The Best Care Begins With Self-Care: An Educational Initiative For Nurses, Betty Sanisidro

Seton Hall University Dissertations and Theses (ETDs)

An educational initiative was developed and implemented to aid in ascertaining if self-care modalities implemented by nurses lead to decreased symptoms of compassion fatigue and burnout, to support current research that self-care practices do prevent compassion fatigue and burnout, and to enhance the growing body of evidence to support nursing and self-care practices. This educational initiative and preventive program included the creation and implementation of a one-hour training session for early identification of burnout among occupational health nurses with a follow up self-enrollment in a four-week initiative focusing on self-compassion interventions and Mindful Self Compassion (MSC) for participating nurses. This …

Review Of A Common Nomenclature, Michael D. Staudt

Conference Presentation Abstracts

No abstract provided.

Case Reports On Disorders Of Sound Tolerance: Misophonia And Hyperacusis, Madison Mcconville, Antony Joseph

AuD Capstone Projects - Communication Sciences and Disorders

Introduction: Misophonia is a rare disorder affecting approximately one in 1,500 people, of which, a small percentage are pediatric patients. Misophonia is characterized by the dislike of an explicit sound in a specific context. Treatment for misophonia includes a four-step program that can be modified for pediatrics. Case Presentation: A young female presented to the clinic with a significant distressed reaction when in the presence of specific sounds that included chewing, clicking pens, and loud music bass tones. Discussion: Treatment of misophonia is comparable to a care-plan for both tinnitus and hyperacusis. For this case, a four-step approach was used …

South To North Migration Patterns Of Tuberculosis Patients Diagnosed In The Mexican Border With Texas, Jennifer S. Curry, Bassent Abdelbary, Moncerrato García-Viveros, Juan Ignacio Garcia, Marcel Yotebieng, Adrian Rendon, Jordi B. Torrelles, Blanca I. Restrepo

School of Medicine Publications

The Mexican state of Tamaulipas serves as a migration waypoint into the US. Here, we determined the contribution of immigrants to TB burden in Tamaulipas. TB surveillance data from Tamaulipas (2006–2013) was used to conduct a cross-sectional characterization of TB immigrants (born outside Tamaulipas) and identify their association with TB treatment outcomes. Immigrants comprised 30.8% of TB patients, with > 99% originating from internal Mexican migration. Most migration was from South to North, with cities adjacent to the US border as destinations. Immigrants had higher odds of risk factors for TB [older age (≥ 65 year old, OR 2.4, 95% CI …