Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences Commons™

Open Access. Powered by Scholars. Published by Universities.®

2021

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 1831 - 1860 of 21398

Full-Text Articles in Medicine and Health Sciences

Understanding The Relationship Between Kangaroo Care And Neurodevelopment In Infants With Congenital Heart Disease: A Systematic Review, Natalie Geralde, Alexis Antoci, Anne Aca, Kamrin Burdell Nov 2021

Understanding The Relationship Between Kangaroo Care And Neurodevelopment In Infants With Congenital Heart Disease: A Systematic Review, Natalie Geralde, Alexis Antoci, Anne Aca, Kamrin Burdell

Symposium of Student Scholars

Background: Infants with congenital heart disease (CHD) are predisposed to significant neurodevelopmental delays related to disrupted parent-infant bonding, stress caused by invasive cardiac interventions, and overstimulating environments, such as the cardiac intensive care unit. Early promotion of neurodevelopment in infants with CHD is essential to support their overall health and quality of life, and to diminish the extent of neurocognitive delays. However, there is limited research examining the relationship between neurodevelopment in infants with CHD and the benefits of kangaroo care.

Objective: The purpose of the systematic review was to evaluate the effectiveness of kangaroo care and touch on optimal …


Prolonged Hospitalization Effects On Psychosocial Development In Chronic Illness Pediatric Patients, Zoe Quarles, Courtney Cumberland, Megan Pringle, Sophie Kinrade Nov 2021

Prolonged Hospitalization Effects On Psychosocial Development In Chronic Illness Pediatric Patients, Zoe Quarles, Courtney Cumberland, Megan Pringle, Sophie Kinrade

Symposium of Student Scholars

Prolonged hospitalization effects on psychosocial development in chronic illness pediatric populations

Abstract

Courtney Cumberland, Sophie Kinrade, Megan Pringle, and Zoe Quarles

Background/Objective: Frequent and extensive hospitalizations have a negative impact on the psychosocial development of children in the most formative years of their lives. This problem is most evident in children who have chronic disease or health conditions that require multiple hospital stays and interventions. This topic can be considered broad because of the extensive variety of chronic conditions and how that determines a child's length of stay. This study aims to identify whether patient-to-patient interaction impacts the psychosocial development …


The Relationship Between Self-Reported Exercise Levels During Pregnancy And Labor Pains, Jaiden Outten, Maria Johnson, Katherine Ingram Ph.D., Sadaf Dabeer Ph.D., Julianna Filguerias Meireles Ph.D., Janeen Amason R.N., Ph.D Nov 2021

The Relationship Between Self-Reported Exercise Levels During Pregnancy And Labor Pains, Jaiden Outten, Maria Johnson, Katherine Ingram Ph.D., Sadaf Dabeer Ph.D., Julianna Filguerias Meireles Ph.D., Janeen Amason R.N., Ph.D

Symposium of Student Scholars

Abstract

Background: Physical activity is important to maintain overall health and wellness even during pregnancy. There are numerous benefits to exercise during pregnancy that include reduced back pain and lower risk of preeclampsia and gestational diabetes. Recent studies have shown an association between aerobic exercise and reduction in the intensity of labor pains. Purpose: The purpose of this study is to determine the association among level of exercise level and the intensity of pain during active labor. Methods: Women up to 2 years postpartum were invited to complete an online survey about the frequency of exercise (none, occasionally, a few …


Realist Evaluation Of The Early-Stage Implementation Of A Smartphone-Based Disease Surveillance Project In Two Armed-Conflict Communities In Nigeria, Bashir M. Mustapha, Samuel C. Avemaria Utulu Nov 2021

Realist Evaluation Of The Early-Stage Implementation Of A Smartphone-Based Disease Surveillance Project In Two Armed-Conflict Communities In Nigeria, Bashir M. Mustapha, Samuel C. Avemaria Utulu

The African Journal of Information Systems

We investigate the early-stage implementation of a smartphone-based acute flaccid paralysis (AFP) surveillance project in communities experiencing armed conflicts in Nigeria. We aim to expose factors influencing the early-stage implementation of smartphone-based AFP surveillance in two rural communities experiencing armed conflicts in Northern Nigeria. Thus, exploring “what works, for whom and under what contextual conditions?” in the early-stage implementation of a smartphone-based AFP surveillance project, given the involvement of multiple stakeholders. We adopted stakeholder theory as a lens to guide the study. We adopted a qualitative case study method, realist philosophy, semi-structured interview, participatory observation, and thematic data analysis. The …


2021-11-17 Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services Nov 2021

2021-11-17 Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.


Forward Together Update [Thanksgiving Break Update], November 17, 2021, University Of Northern Iowa Nov 2021

Forward Together Update [Thanksgiving Break Update], November 17, 2021, University Of Northern Iowa

UNI Response to COVID-19

Information about vaccination rates in Iowa and a reminder that on-campus vaccinations are still available.


A Quasi-Experimental Study Of Medicaid Expansion And Urban Mortality In The American Northeast., Cyrus Ayubcha, Pedram Pouladvand, Soussan Ayubcha Nov 2021

A Quasi-Experimental Study Of Medicaid Expansion And Urban Mortality In The American Northeast., Cyrus Ayubcha, Pedram Pouladvand, Soussan Ayubcha

Marcus Institute of Integrative Health Faculty Papers

Objectives: To investigate the association of state-level Medicaid expansion and non-elderly mortality rates from 1999 to 2018 in Northeastern urban settings.

Methods: This quasi-experimental study utilized a synthetic control method to assess the association of Medicaid expansion on non-elderly urban mortality rates [1999-2018]. Counties encompassing the largest cities in the Northeastern Megalopolis (Washington D.C., Baltimore, Philadelphia, New York City, and Boston) were selected as treatment units (n = 5 cities, 3,543,302 individuals in 2018). Cities in states without Medicaid expansion were utilized as control units (n = 17 cities, 12,713,768 individuals in 2018).

Results: Across all cities, there …


The Use Of Zero Balancing In Vestibular Rehabilitation, Mary L. Behrens Nov 2021

The Use Of Zero Balancing In Vestibular Rehabilitation, Mary L. Behrens

Journal of Transformative Touch

This case study highlights a patient referred for vestibular rehabilitation with vestibular migraine, who was unable to take migraine medication. He was treated with Zero Balancing, a manual therapy technique that balances body structure with energy. After seven treatments his migraines were relieved and he no longer needed therapy.


2021-11-17_Michigandaily_Covidmap, Michigan Department Of Health & Human Services Nov 2021

2021-11-17_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …


(De)Constructing ‘Therapeutic Itineraries’ Of Hypertension Care: A Qualitative Study In The Philippines, Jhaki A. Mendoza, Gideon Lasco, Alicia Renedo, Lia M. Palileo-Villanueva, Maureen L. Seguin, Benjamin Palafox, Arianna Maever L. Amit, Veincent Christian F. Pepito, Martin Mckee, Dina Balabanova Nov 2021

(De)Constructing ‘Therapeutic Itineraries’ Of Hypertension Care: A Qualitative Study In The Philippines, Jhaki A. Mendoza, Gideon Lasco, Alicia Renedo, Lia M. Palileo-Villanueva, Maureen L. Seguin, Benjamin Palafox, Arianna Maever L. Amit, Veincent Christian F. Pepito, Martin Mckee, Dina Balabanova

Development Studies Faculty Publications

Hypertension, a major risk factor for non-communicable diseases, remains poorly controlled in many countries. In the Philippines, it is still one of the leading causes of preventable deaths despite the accessibility and availability of essential technologies and medicine to detect and treat hypertension. This paper characterizes the ‘therapeutic itineraries’ of people with hypertension from poor communities in rural and urban settings in the Philippines. We employ longitudinal qualitative methodology comprised of repeat interviews and digital diaries using mobile phones from 40 recruited participants in 12 months. Our findings demonstrate that therapeutic itineraries, rather than being organized according to categories that …


Magnetic Resonance Imaging Sequence Identification Using A Metadata Learning Approach, Shuai Liang, Derek Beaton, Stephen R. Arnott, Tom Gee, Mojdeh Zamyadi, Robert Bartha, Sean Symons, Glenda M. Macqueen, Stefanie Hassel, Jason P. Lerch, Evdokia Anagnostou, Raymond W. Lam, Benicio N. Frey, Roumen Milev, Daniel J. Müller, Sidney H. Kennedy, Christopher J.M. Scott, Stephen C. Strother Nov 2021

Magnetic Resonance Imaging Sequence Identification Using A Metadata Learning Approach, Shuai Liang, Derek Beaton, Stephen R. Arnott, Tom Gee, Mojdeh Zamyadi, Robert Bartha, Sean Symons, Glenda M. Macqueen, Stefanie Hassel, Jason P. Lerch, Evdokia Anagnostou, Raymond W. Lam, Benicio N. Frey, Roumen Milev, Daniel J. Müller, Sidney H. Kennedy, Christopher J.M. Scott, Stephen C. Strother

Medical Biophysics Publications

Despite the wide application of the magnetic resonance imaging (MRI) technique, there are no widely used standards on naming and describing MRI sequences. The absence of consistent naming conventions presents a major challenge in automating image processing since most MRI software require a priori knowledge of the type of the MRI sequences to be processed. This issue becomes increasingly critical with the current efforts toward open-sharing of MRI data in the neuroscience community. This manuscript reports an MRI sequence detection method using imaging metadata and a supervised machine learning technique. Three datasets from the Brain Center for Ontario Data Exploration …


Intermediate Care Technicians-A Novel Workforce For Veterans Affairs Geriatric Emergency Departments, Kristina T. Snell, Thomas Edes, Colleen M. Mcquown Nov 2021

Intermediate Care Technicians-A Novel Workforce For Veterans Affairs Geriatric Emergency Departments, Kristina T. Snell, Thomas Edes, Colleen M. Mcquown

Journal of Geriatric Emergency Medicine

No abstract provided.


St-Segment Elevation In A Patient With Nausea, Vomiting, And Intracerebral Hemorrhage, Ranjan Banerjee, Dustin Hillerson, Steve W. Leung, Vincent L. Sorrell Nov 2021

St-Segment Elevation In A Patient With Nausea, Vomiting, And Intracerebral Hemorrhage, Ranjan Banerjee, Dustin Hillerson, Steve W. Leung, Vincent L. Sorrell

Gill Heart & Vascular Institute Faculty Publications

A 60-year-old man who presented with nausea, vomiting, and intracerebral hemorrhage developed inferior ST-segment elevation and angina. Coronary angiography showed no coronary obstruction. The patient was found to have a small bowel obstruction causing superior translocation of the heart. Relief of obstruction caused immediate resolution of electrocardiographic changes and symptoms. (Level of Difficulty: Beginner.)


2021-11-17_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services Nov 2021

2021-11-17_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. COVID case and testing data will be posted three times a week on Mondays, Wednesdays and Fridays.

This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time …


Human Papillomavirus-Associated Anal Squamous Intraepithelial Lesions In Men Who Have Sex With Men And Transgender Women Living With And Without Hiv In Karachi Pakistan: Implications For Screening And Prevention, Muslima Ejaz, Muhammad Mubarak, Tazeen Saeed Ali, Sören Andersson, Anna Mia Ekström Nov 2021

Human Papillomavirus-Associated Anal Squamous Intraepithelial Lesions In Men Who Have Sex With Men And Transgender Women Living With And Without Hiv In Karachi Pakistan: Implications For Screening And Prevention, Muslima Ejaz, Muhammad Mubarak, Tazeen Saeed Ali, Sören Andersson, Anna Mia Ekström

Community Health Sciences

Background: Anal squamous intraepithelial lesions (ASIL), strongly related to human papilloma virus (HPV) infection, is more prevalent among men who have sex with men (MSM). However, no such data are available for Pakistan yet, and neither HPV vaccination nor anal-cytology screening is implemented in Pakistan. The purpose of this first ever study was to assess the prevalence of HPV-related anal cytological abnormalities among MSM and transgender women living with and without HIV infection in Pakistan.
Methods: We conducted a cross-sectional study from March 2016 to November 2017 at sexual health centers run by the Perwaaz Trust and the National AIDS …


Shaper-Pnd Trial: Clinical Effectiveness Protocol Of A Community Singing Intervention For Postnatal Depression, Carolina Estevao, Rebecca Bind, Daisy Fancourt, Kristi Sawyer, Paola Dazzan, Nick Sevdalis, Anthony Woods, Nikki Crane, Lavinia Rebecchini, Katie Hazelgrove, Manonmani Manoharan, Alexandra Burton, Hannah Dye, Tim Osborn, Rachel E. Davis, Tayana Soukup, Jorge Arias De La Torre, Ioannis Bakolis, Andy Healey, Rosie Perkins, Carmine Pariante Nov 2021

Shaper-Pnd Trial: Clinical Effectiveness Protocol Of A Community Singing Intervention For Postnatal Depression, Carolina Estevao, Rebecca Bind, Daisy Fancourt, Kristi Sawyer, Paola Dazzan, Nick Sevdalis, Anthony Woods, Nikki Crane, Lavinia Rebecchini, Katie Hazelgrove, Manonmani Manoharan, Alexandra Burton, Hannah Dye, Tim Osborn, Rachel E. Davis, Tayana Soukup, Jorge Arias De La Torre, Ioannis Bakolis, Andy Healey, Rosie Perkins, Carmine Pariante

Faculty Publications

INTRODUCTION: Postnatal depression (PND) affects approximately 13% of new mothers. Community-based activities are sought after by many mothers, especially mothers that prefer not to access pharmacological or psychological interventions. Singing has shown positive effects in maternal mood and mother-child bonding. The Scaling-Up Health-Arts Programmes: Implementation and Effectiveness Research-Postnatal Depression study will analyse the clinical and implementation effectiveness of 10-week singing sessions for PND in new mothers. This protocol paper will focus on the clinical effectiveness of this trial. METHODS AND ANALYSIS: A total of 400 mothers with PND (with a score of at least 10 on the Edinburgh Postnatal Depression …


Hand Hygiene And Covid Education At Women’S Shelter, Anastasiya Yerina, Cristal Garibay, Henok Tewolde, Muskan Priya, Jeannie Lee Nov 2021

Hand Hygiene And Covid Education At Women’S Shelter, Anastasiya Yerina, Cristal Garibay, Henok Tewolde, Muskan Priya, Jeannie Lee

Nursing Leadership in Community Engagement Projects

Introduction

In 2020, there were around 580,000 people experiencing homelessness in the US with about 39% of them in unsheltered locations (Montgomery et al., 2021). Many homeless women experience safety issues and have severely impacted physical and mental health, so finding shelter is crucial in efforts to improve their well being (Sarla, 2020). Women’s Shelter is a shelter for single homeless women in downtown Seattle that provides daily meals, laundry services, and overnight shelter. After assessing the women by visiting Angeline’s, the group found that hand hygiene was an issue among the women. Then, the group decided to focus on …


Mental Health Training, Adrienne Leonard, Seanghai Lim, Emma Booth, Jaeger Mccaulou, Saori Fukuoka Nov 2021

Mental Health Training, Adrienne Leonard, Seanghai Lim, Emma Booth, Jaeger Mccaulou, Saori Fukuoka

Nursing Leadership in Community Engagement Projects

Introduction

New Horizons is a Seattle-based non-profit organization that serves to aid homeless youth in the greater Seattle area, with an end goal of ending youth homelessness in Seattle and King County. New Horizons has been operating since 1978 and has reached out to homeless youth of all different backgrounds in order to meet their basic needs and help transition them into a stable living environment. (New Horizons, 2016). This type of work requires staff and volunteers to be able to accommodate a wide range of cultural backgrounds, lifestyle habits, and crucially, individuals with differing mental health states and disabilities. …


Promoting Health Independence Through Accessible Health Resources, Haylee R. Gilman, Lucy Carrasco Flores, Keenan Haack, Hui Jean Liew, Gebrehiwot Abrha Nov 2021

Promoting Health Independence Through Accessible Health Resources, Haylee R. Gilman, Lucy Carrasco Flores, Keenan Haack, Hui Jean Liew, Gebrehiwot Abrha

Nursing Leadership in Community Engagement Projects

Introduction

The U.S. Department of Housing and Urban Development (HUD, 2018) defines an individual or family as homeless, as someone who lacks “fixed, regular, and adequate nighttime residence”. As of January 2020, there were an estimated 11,751 individuals experiencing homelessness in Seattle/King County (King County Regional Homelessness Authority, 2020). National Alliance to End Homelessness (2020) explains that health and homelessness are inextricably linked, where an acute physical or behavioral health crisis or any long-term disabling condition may lead to homelessness; homelessness itself can exacerbate chronic medical conditions. To reduce the number of homeless families on the streets in King County, …


Dermatomyositis- Related Intestinal Dysmotility, Christine Loftis, Rosa White, Emilia C. Dulgheru Nov 2021

Dermatomyositis- Related Intestinal Dysmotility, Christine Loftis, Rosa White, Emilia C. Dulgheru

School of Medicine Publications

Dermatomyositis (DM) is an inflammatory myopathy (IIM) characterized by proximal muscle weakness and pathognomonic skin lesions. A 69-year-old woman with a recent diagnosis of DM 1 month prior, treated with corticosteroids and immunomodulators, presented to our inpatient rehabilitation with worsening dysphagia and constipation. At the time of our evaluation, physical examination was notable for erythematous papules over the metacarpophalangeal joints, proximal interphalangeal joints, elbows, and knees as well as a violaceous rash on the face. Muscle strength was diminished bilaterally with proximal distribution being affected greater than distal. Laboratory studies were notable for the creatine kinase (CK) level of 31 …


Adult Spiny Mice (Acomys) Exhibit Endogenous Cardiac Recovery In Response To Myocardial Infarction, Hsuan Peng, Kazuhiro Shindo, Renée R. Donahue, Erhe Gao, Brooke M. Ahern, Bryana M. Levitan, Himi Tripathi, David Powell, Ahmed Noor, Garrett A. Elmore, Jonathan Satin, Ashley W. Seifert, Ahmed K. Abdel-Latif Nov 2021

Adult Spiny Mice (Acomys) Exhibit Endogenous Cardiac Recovery In Response To Myocardial Infarction, Hsuan Peng, Kazuhiro Shindo, Renée R. Donahue, Erhe Gao, Brooke M. Ahern, Bryana M. Levitan, Himi Tripathi, David Powell, Ahmed Noor, Garrett A. Elmore, Jonathan Satin, Ashley W. Seifert, Ahmed K. Abdel-Latif

Physiology Faculty Publications

Complex tissue regeneration is extremely rare among adult mammals. An exception, however, is the superior tissue healing of multiple organs in spiny mice (Acomys). While Acomys species exhibit the remarkable ability to heal complex tissue with minimal scarring, little is known about their cardiac structure and response to cardiac injury. In this study, we first examined baseline Acomys cardiac anatomy and function in comparison with commonly used inbred and outbred laboratory Mus strains (C57BL6 and CFW). While our results demonstrated comparable cardiac anatomy and function between Acomys and Mus, Acomys exhibited a higher percentage of cardiomyocytes displaying …


Leukotrienes Are Dispensable For Vaginal Neutrophil Recruitment As Part Of The Immunopathological Response During Experimental Vulvovaginal Candidiasis, Junko Yano, David J. White, Anthony P. Sampson, Floyd L. Wormley, Paul L. Fidel Nov 2021

Leukotrienes Are Dispensable For Vaginal Neutrophil Recruitment As Part Of The Immunopathological Response During Experimental Vulvovaginal Candidiasis, Junko Yano, David J. White, Anthony P. Sampson, Floyd L. Wormley, Paul L. Fidel

School of Dentistry Faculty Publications

Recruitment of polymorphonuclear neutrophils (PMNs) into the vaginal lumen is the hallmark of an acute immunopathologic inflammatory response during vulvovaginal candidiasis (VVC) caused by Candida albicans. Recurrent VVC (RVVC) remains a chronic health burden in affected women worldwide despite the use of antifungal therapy. Based on the role leukotrienes (LTs) play in promoting inflammation, leukotriene receptor antagonists (LTRAs) targeted for LTB4 (etalocib) or LTC4, LTD4, and LTE4 (zafirlukast or montelukast) have been shown to reduce inflammation of epithelial tissues. An open-label pilot study using long-term regimens of zafirlukast in women with RVVC indicated the potential for some relief from recurrent …


Improving Patient Flow In The Urgent Care Setting, Stephanie Carpenter Nov 2021

Improving Patient Flow In The Urgent Care Setting, Stephanie Carpenter

Student Scholarly Projects

Practice Problem: Urgent care clinics provide care to patients with non-life-threatening illnesses or injuries and are found to be less expensive and more convenient than emergency departments. As urgent care clinics are growing in popularity so are the patient wait times and overall length of stay times.

PICOT: The PICOT question that guided this project was in urgent care clinic patients (P), how does utilizing the Emergency Severity Index (ESI) as a patient triage tool (I) compared to using no patient triage tool (C) affect the patient flow and patient wait times (O) within 13 weeks.

Evidence: Evidence search with …


Evaluation Of The United States Covid-19 Vaccine Allocation Strategy, Md Rafiul Islam, Tamer Oraby, Audrey Mccombs, Mohammad Mihrab Chowdhury, Mohammad Al-Mamun, Michael G. Tyshenko, Claus Kadelkai Nov 2021

Evaluation Of The United States Covid-19 Vaccine Allocation Strategy, Md Rafiul Islam, Tamer Oraby, Audrey Mccombs, Mohammad Mihrab Chowdhury, Mohammad Al-Mamun, Michael G. Tyshenko, Claus Kadelkai

School of Mathematical & Statistical Sciences Faculty Publications

Background: Anticipating an initial shortage of vaccines for COVID-19, the Centers for Disease Control (CDC) in the United States developed priority vaccine allocations for specific demographic groups in the population. This study evaluates the performance of the CDC vaccine allocation strategy with respect to multiple potentially competing vaccination goals (minimizing mortality, cases, infections, and years of life lost (YLL)), under the same framework as the CDC allocation: four priority vaccination groups and population demographics stratified by age, comorbidities, occupation and living condition (congested or non-congested).

Methods and findings: We developed a compartmental disease model that incorporates key elements of the …


Acquired Factor Viii Deficiency Presenting As Gross Hematuria In A Hispanic, Pregnant Patient With Previously Undiagnosed Connective Tissue Disease, Christine Loftis, Emilia C. Dulgheru, Rosa White Nov 2021

Acquired Factor Viii Deficiency Presenting As Gross Hematuria In A Hispanic, Pregnant Patient With Previously Undiagnosed Connective Tissue Disease, Christine Loftis, Emilia C. Dulgheru, Rosa White

School of Medicine Publications

Acquired factor VIII deficiency is a bleeding disorder caused by the presence of autoantibodies against clotting factor VIII. We report a case of a 24-year-old pregnant woman who presented with gross hematuria secondary to acquired factor VIII deficiency in the presence of a previously undiagnosed connective tissue disease. *is article includes a literature review of pregnancy-related cases of acquired factor VIII deficiency. We also reviewed various therapeutic approaches for the management of the acquired factor inhibitor which include achieving hemostasis and elimination of the inhibitor via immunosuppressive agents. *is case report describes the rare presentation of acquired factor VIII deficiency …


Prognostic Values Of G-Protein Mutations In Metastatic Uveal Melanoma, Mizue Terai, Ayako Shimada, I Chervoneva, Liam Hulse, Meggie Danielson, Jeff Swensen, Marlana Orloff, Philip B Wedegaertner, Jeffrey L Benovic, A E Aplin, Takami Sato Nov 2021

Prognostic Values Of G-Protein Mutations In Metastatic Uveal Melanoma, Mizue Terai, Ayako Shimada, I Chervoneva, Liam Hulse, Meggie Danielson, Jeff Swensen, Marlana Orloff, Philip B Wedegaertner, Jeffrey L Benovic, A E Aplin, Takami Sato

Department of Medical Oncology Faculty Papers

Uveal melanoma is the most common primary ocular malignancy in adults, characterized by gene mutations in G protein subunit alpha q (GNAQ) and G protein subunit alpha 11 (GNA11). Although they are considered to be driver mutations, their role in MUM remains elusive. We investigated key somatic mutations of MUM and their impact on patients’ survival after development of systemic metastasis (Met-to-Death). Metastatic lesions from 87 MUM patients were analyzed by next generation sequencing (NGS). GNA11 (41/87) and GNAQ (39/87) mutations were most predominantly seen in MUM. Most GNA11 mutations were Q209L (36/41), whereas GNAQ mutations comprised Q209L (14/39) and …


Insights Into Using Plants In Management Of Viral Diseases., Vyacheslav Dushenkov, Anna Dushenkov Nov 2021

Insights Into Using Plants In Management Of Viral Diseases., Vyacheslav Dushenkov, Anna Dushenkov

Publications and Research

Botanical therapeutics possess a unique potential in the treatment of viral diseases. The pharmacological base and clinical use of botanical therapeutics have been extensively reviewed. The mode of action(s) may be built either on the direct interference with the virus's ability to enter human cells, virus replication, or exerting immune-modulatory and anti-inflammatory effects. The adjuvant treatment with botanical therapeutics has the potential to result in advances in symptom resolution, decrease in disease burden and shortening its duration.


Evaluating The Efficacy Of Automated Smoking Treatment For People With Hiv: Protocol For A Randomized Controlled Trial, Damon J Vidrine, Thanh C Bui, Michael S Businelle, Ya-Chen Tina Shih, Steven K Sutton, Lokesh Shahani, Diana Stewart Hoover, Kristina Bowles, Jennifer I Vidrine Nov 2021

Evaluating The Efficacy Of Automated Smoking Treatment For People With Hiv: Protocol For A Randomized Controlled Trial, Damon J Vidrine, Thanh C Bui, Michael S Businelle, Ya-Chen Tina Shih, Steven K Sutton, Lokesh Shahani, Diana Stewart Hoover, Kristina Bowles, Jennifer I Vidrine

Faculty, Staff and Student Publications

BACKGROUND: Smoking prevalence rates among people with HIV are nearly 3 times higher than those in the general population. Nevertheless, few smoking cessation trials targeting smokers with HIV have been reported in the literature. Efforts to develop and evaluate sustainable, low-cost, and evidence-based cessation interventions for people with HIV are needed. Given the widespread proliferation of mobile phones, the potential of using mobile health apps to improve the reach and efficacy of cessation interventions is promising, but evidence of efficacy is lacking, particularly among people with HIV.

OBJECTIVE: This study will consist of a 2-group randomized controlled trial to evaluate …


Muscle Damage Indicated By Maximal Voluntary Contraction Strength Changes From Immediately To 1 Day After Eccentric Exercise Of The Knee Extensors, Mikio Shoji, Ryoichi Ema, Kazunori Nosaka, Akihiro Kanda, Kosuke Hirata, Ryota Akagi Nov 2021

Muscle Damage Indicated By Maximal Voluntary Contraction Strength Changes From Immediately To 1 Day After Eccentric Exercise Of The Knee Extensors, Mikio Shoji, Ryoichi Ema, Kazunori Nosaka, Akihiro Kanda, Kosuke Hirata, Ryota Akagi

Research outputs 2014 to 2021

The present study examined if the magnitude of changes in indirect muscle damage markers could be predicted by maximal voluntary isometric contraction (MVIC) torque changes from immediately to 1 day after eccentric exercise. Twenty-eight young men performed 100 maximal isokinetic (60°/s) eccentric contractions of the knee extensors. MVIC torque, potentiated doublet torque, voluntary activation (VA) during MVIC, shear modulus of rectus femoris (RF), vastus medialis and lateralis, and muscle soreness of these muscles were measured before, immediately after, and 1–3 days post-exercise. Based on the recovery rate of the MVIC torque from immediately to 1-day post-exercise, the participants were placed …


Zwolle Risk Score For Safety Assessment Of Same-Day Discharge After Primary Percutaneous Coronary Intervention, Jehangir Ali Shah, Bashir Ahmed Solangi, Mahesh Kumar Batra, Kamran Ahmed Khan, Ghazanfar Ali Shah, Gulzar Ali, Mehwish Zehra, Muhammad Hassan, Muhammad Zubair, Musa Karim Nov 2021

Zwolle Risk Score For Safety Assessment Of Same-Day Discharge After Primary Percutaneous Coronary Intervention, Jehangir Ali Shah, Bashir Ahmed Solangi, Mahesh Kumar Batra, Kamran Ahmed Khan, Ghazanfar Ali Shah, Gulzar Ali, Mehwish Zehra, Muhammad Hassan, Muhammad Zubair, Musa Karim

Journal of the Saudi Heart Association

Objectives: The Zwolle risk score (ZRS) has been considered to be a useful tool for the systematic evaluation of patients for early discharge after primary percutaneous coronary intervention (PCI). Therefore, aim of this study was to evaluate the clinical utility of ZRS for the same-day discharge strategy after primary PCI at a tertiary care cardiac center of Karachi, Pakistan. Methods: This study was conducted at a tertiary care cardiac center between August 2019 and July 2020. Patients discharged within 24 hours (same-day) of the primary PCI procedure were included. Patients were stratified as high- and low-risk based on ZRS score; …