Medicine and Health Sciences Commons^™

Sem And Energy Dispersive X-Ray Evaluation Of Smear Layer Removal Using Standard And Innovative Irrigation Protocols: A Comparative In Vitro Study, Hala Khalil, Lamia Ibrahim

Dentistry

ABSTRACT

Aim: Compare efficacy of Dual Rinse HEDP with sodium hypochlorite to sodium hypochlorite in combination with a finishing rinse with 17% EDTA solution to remove the smear layer.

Materials and methods: Sixteen human maxillary single-rooted, single canalled sound premolars were used. Specimens were distributed into 2 groups and labeled according to irrigation protocol used. Each group consisted of 8 specimens: Group 1 50% NaOCl followed by 17% EDTA. Group 2 The Dual Rinse® HEDP mixed with 50% NaOCl. Roots were prepared for SEM appraisal. The smear layer was assessed and scored. Energy-dispersive X-ray analysis was used to analyze the …

Assessment The Propolis Effect Versus Calcium Hydroxide Effect As Intracanal Medications On Post-Operative Pain In Necrotic Teeth, Engy M. Kataia

Dentistry

Aim: to evaluate the postoperative pain of using Propolis versus Calcium hydrox- ide as intracanal medications on post-operative pain in necrotic teeth. Subjects and Methods: 40 patients requiring endodontic treatment for single rooted teeth were en- rolled in this analysis. The selected patients were separated into two groups with 20 pa- tients each; Group І: Propolis paste. Group II: Ca (OH)2 paste. The local anesthesia was administrated, and the working length determined by Root ZX apex locator, and then confirmed radiographically. The root canals were mechanically prepared in a crown- down approach using the “TF Adaptive” setting on Elements Motor. …

Occupational Health Practices Among Dental Care Professionals Before And During The Covid-19 Pandemic, Sean Banaee, Denise M. Claiborne, Muge Akpinar-Elci

Community & Environmental Health Faculty Publications

BACKGROUND: The COVID-19 pandemic has posed a substantial burden on dental care professionals. While dentistry is known as one of the most exposed and high-risk professions, dental care professionals are indeed at even greater risk.

OBJECTIVE: The aim of this study was to assess knowledge, attitudes, occupational health practices, personal protective equipment usage, and mental stressors during COVID-19 pandemic among dental care professionals.

METHODS: A cross-sectional study was conducted among dental care professionals who were subscribers to a dental hygiene journal using a self-administered online survey (n = 1047 respondents). Cross-tabulations were performed to determine differences in the responses to …

Trends And Opportunities In Tick-Borne Disease Geography, Catherine A. Lippi, Sadie J. Ryan, Alexis L. White, Holly D. Gaff, Colin J. Carlson

Biological Sciences Faculty Publications

Tick-borne diseases are a growing problem in many parts of the world, and their surveillance and control touch on challenging issues in medical entomology, agricultural health, veterinary medicine, and biosecurity. Spatial approaches can be used to synthesize the data generated by integrative One Health surveillance systems, and help stakeholders, managers, and medical geographers understand the current and future distribution of risk. Here, we performed a systematic review of over 8,000 studies and identified a total of 303 scientific publications that map tick-borne diseases using data on vectors, pathogens, and hosts (including wildlife, livestock, and human cases). We find that the …

Data On Breastfeeding And State Policies In The United States, Chun Chen, Hong Xue, Qi Zhang

Community & Environmental Health Faculty Publications

Breastfeeding is critically important to maternal and child health in the United States. Examining the relationship between breastfeeding outcomes and state policies requires multidisciplinary efforts to link data from various sources. This article describes an integrated dataset that was used to understand the relationship between participation in a nutrition assistance program and low-income children's breastfeeding outcomes [1]. This dataset merged public health information from the National Immunization Surveys Data from 2006 to 2016 and matching state policy data from the Correlates of State Policy Project (CSPP), the U.S. Department of Agriculture/Economic Research Services (USDA/ERS) Supplemental Nutrition Assistance Program (SNAP) Policy …

Influence Of The Inherent Safety Principles On Quantitative Risk In Process Industry: Application Of Genetic Algorithm Process Optimization (Gapo), Mehdi Jahangiri, Abolfazl Moghadasi, Mojtaba Kamalinia, Farid Sadeghianjahromi, Sean Banaee

Community & Environmental Health Faculty Publications

Inherent safety (IS) refers to a set of measures that enhance the safety level of processes and equipment, rendering additional equipment and/or add-ons. The early design phase of processes is suited best for implementation of IS strategies as some of such strategies either are impossible to be implemented at the operation phase or substantially increase costs. The purpose of this study is to present a new approach called genetic algorithm process optimization (GAPO), by which processes can be made inherently safer even at the operation phase. This study simulates the IS principle, assessing its impact on quantitative risk and the …

Income-Related Health Inequality Among Chinese Adults During The Covid-19 Pandemic: Evidence Based On An Online Survey, Peng Nie, Lanlin Ding, Zhou Chen, Shiyong Liu, Qi Zhang, Zumin Shi, Lu Wang, Hong Xue, Gordon G. Liu, Youfa Wang

Community & Environmental Health Faculty Publications

BACKGROUND: Partial- or full-lockdowns, among other interventions during the COVID-19 pandemic, may disproportionally affect people (their behaviors and health outcomes) with lower socioeconomic status (SES). This study examines income-related health inequalities and their main contributors in China during the pandemic.

METHODS: The 2020 China COVID-19 Survey is an anonymous 74-item survey administered via social media in China. A national sample of 10,545 adults in all 31 provinces, municipalities, and autonomous regions in mainland China provided comprehensive data on sociodemographic characteristics, awareness and attitudes towards COVID-19, lifestyle factors, and health outcomes during the lockdown. Of them, 8448 subjects provided data for …

A Global Perspective Of Advanced Practice Nursing Research: A Review Of Systematic Reviews, Colette Henderson, Abby Kra-Friedman, Li-Anne Audet, Isabelle Savard, Lori A. Spies, Heather Mcgrath, Wentao Zhou, Kathy Wheeler, Elissa Ladd, Deborah C. Gray, Mra Jabbour, Renée Atallah, Melanie Rogers, Kelley Kilpatrick

Ellmer School of Nursing Faculty Publications

No abstract provided.

Guidelines On Prescriptive Authority For Nurses 2021, David Stewart, Madrean Schober, Lisa Nissen, Elissa Ladd, Kimberley Lamarche, Marie-Lyne Bournival, Deborah Gray, Sonia Sevilla, Marieke Kroezen, Frances Wong

Ellmer School of Nursing Faculty Publications

[First paragraph] Nurse prescribing has existed for over 50 years in some regions of the world. The diverse global nurse prescriptive authority landscape will be highlighted in this important publication. A framework embedding core components for safe and competent prescribers necessitates appropriate education, aligned regulatory authority and continuing professional development to uphold competencies. Evidence-informed models of nurse prescribing will weave in organisational and team support considerations required.

Structual Analysis Of The Cl-Par-4 Tumor Suppressor As A Function Of Ionic Environment, Krishna K. Raut, Komala Ponniah, Steven M. Pascal

Chemistry & Biochemistry Faculty Publications

Prostate apoptosis response-4 (Par-4) is a proapoptotic tumor suppressor protein that has been linked to a large number of cancers. This 38 kilodalton (kDa) protein has been shown to be predominantly intrinsically disordered in vitro. In vivo, Par-4 is cleaved by caspase-3 at Asp-131 to generate the 25 kDa functionally active cleaved Par-4 protein (cl-Par-4) that inhibits NF-κB-mediated cell survival pathways and causes selective apoptosis in tumor cells. Here, we have employed circular dichroism (CD) spectroscopy and dynamic light scattering (DLS) to assess the effects of various monovalent and divalent salts upon the conformation of cl-Par-4 in vitro. We have …

African Environmental Ethics: Keys To Sustainable Development Through Agroecological Villages, Charles Verharen, Flordeliz Bugarin, John Tharakan, Enrico Wensing, Bekele Gutema, Joseph Fortunak, George Middendorf

Center for Global Health Publications

This essay proposes African-based ethical solutions to profound human problems and a working African model to address those problems. The model promotes sustainability through advanced agroecological and information communication technologies. The essay's first section reviews the ethical ground of that model in the work of the Senegalese scholar, Cheikh Anta Diop. The essay's second section examines an applied African model for translating African ethical speculation into practice. Deeply immersed in European and African ethics, Godfrey Nzamujo developed the Songhaï Centers to solve the problem of rural poverty in seventeen African countries. Harnessing advanced technologies within a holistic agroecological ecosystem, Nzamujo's …

The Circle Of Unity: The Power Of Symbols In A Team Sport Context, Brendan O'Hallarn, Craig A. Morehead, Mark A. Slavich, Alicia M. Cintron

University Administration Publications

Modern-day political discord has led to a recent spate of athletes using their platform to make statements about America. One under-researched aspect to modern sport activism is the study of the symbols themselves, such as the controversial kneeling during the national anthem by National Football League players, statement-making pregame apparel worn by National Basketball Association stars, and other political statements. This case study examines a 2016 activist display by Old Dominion University's football team, known as the Circle of Unity. The display, performed before most games that season, began as a form of protest by team captains, and morphed into …

Tetraspanins As Potential Therapeutic Candidates For Targeting Flaviviruses, Waqas Ahmed, Girish Neelakanta, Hameeda Sultana

Biological Sciences Faculty Publications

Tetraspanin family of proteins participates in numerous fundamental signaling pathways involved in viral transmission, virus-specific immunity, and virus-mediated vesicular trafficking. Studies in the identification of novel therapeutic candidates and strategies to target West Nile virus, dengue and Zika viruses are highly warranted due to the failure in development of vaccines. Recent evidences have shown that the widely distributed tetraspanin proteins may provide a platform for the development of novel therapeutic approaches. In this review, we discuss the diversified and important functions of tetraspanins in exosome/extracellular vesicle biology, virus-host interactions, virus-mediated vesicular trafficking, modulation of immune mechanism(s), and their possible role(s) …

The Supportive Care Needs Of Regional And Remote Cancer Caregivers, Anna Stiller, Belinda C. Goodwin, Fiona Crawford-Williams, Sonja March, Michael Ireland, Joanne F. Aitken, Jeff Dunn, Suzanne K. Chambers

Research outputs 2014 to 2021

Objective: As cancer survival rates continue to increase, so will the demand for care from family and friends, particularly in more isolated settings. This study aims to examine the needs of cancer caregivers in regional and remote Australia. Methods: A total of 239 informal (i.e., non-professional) cancer caregivers (e.g., family/friends) from regional and remote Queensland, Australia, completed the Comprehensive Needs Assessment Tool for Cancer Caregivers (CNAT-C). The frequencies of individuals reporting specific needs were calculated. Logistic regression analyses assessed the association between unmet needs and demographic characteristics and cancer type. Results: The most frequently endorsed needs were lodging near hospital …

Exploring The Covid-19 Experience Of Young Adult Latinos In Rural California: Insights Into Mental Health & The Immigrant Health Paradox, Vivianna Plancarte

Pomona Senior Theses

This study expands the COVID-19 and Latino Immigrants in Rural California (CLIMA) Study at UC Merced by exploring how the mental health of young adult Latinos in rural CA has been affected by the COVID-19 pandemic and comparing the experiences of US-born Latinos to those of Latino immigrants to investigate an Immigrant Health Paradox. A convergent mixed methods design was first employed whereby qualitative and quantitative data was collected concurrently, and then merged. Then, the data collected from young adult Latinos was compared to that from Latino immigrants collected by CLIMA Study to explore the Immigrant Health Paradox in the …

Llusd Articulator - Volume 31, Number 2, Loma Linda University School Of Dentistry

Articulator (Dentistry)

Contents:

5 | Dean's Message
8 | Faculty arrive and faculty advance
10 | Mary Hartwell concludes 40 years
11 | LLUSD's 2020 virtual commencement
26 | Student research surmounts the virus
38 | The legacies left by
Dr. Donald Peters,
Dr. Doug Roberts, &
Dr. Elmer Kelln

Assessing The Comfort Of Earplugs: Development And Validation Of The French Version Of The Coprod Questionnaire, Jonathan Terroir, Nellie Perrin, Pascal Wild, Olivier Doutres, Franck Sgard, Chantal Gauvin, Alessia Negrini

Études primaires

Earplugs are a common form of protection for workers exposed to hazardous noise levels. Their comfort directly impacts the effective protection by influencing their consistent and correct use. Nevertheless, comfort definition may vary according to the studies. Thus, a previous review of the literature has shown that to improve our understanding of perceived comfort and to reduce measurement variability, it is advisable to consider comfort through a multidimensional construct (physical, acoustical, functional and psychological). On this basis, the COPROD (COnfort des PROtections auDitives/COmfort of hearing PROtection Devices) questionnaire was developed. It is intended for people working in noisy environments. Nine …

A Comparison Of Exhaustive And Non-Lattice-Based Methods For Auditing Hierarchical Relations In Gene Ontology, Rashmie Abeysinghe, Fengbo Zheng, Licong Cui

Faculty, Staff and Student Publications

Uncovering and fixing errors in biomedical terminologies is essential so that they provide accurate knowledge to downstream applications that rely on them. Non-lattice-based methods have been applied to identify various kinds of inconsistencies in different biomedical terminologies. In previous work, we have introduced two inference-based approaches that were applied in an exhaustive manner to audit hierarchical relations in the Gene Ontology: (1) Lexical-based inference framework, and (2) Subsumption-based sub-term inference framework. However, it is unclear how effective these exhaustive approaches perform compared with their corresponding non-lattice-based approaches. Therefore, in this paper, we implement the non-lattice versions of these two exhaustive …

05-04-2021 Hsc Committee Meeting Minutes, Hsc Committee

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

10-12-2021 Hsc Committee Meeting Minutes, Hsc Committee

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

02-09-2021 Hsc Commmittee Meeting, Hsc Committee

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

03-08-2022 Hsc Committee, Hsc Committee

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

Future Implications Of Telehealth In Post-Covid World, Sujatha Alla, Vijay Kumar Chattu

Engineering Management & Systems Engineering Faculty Publications

[Introduction] The recent global pandemic forced telehealth to play a greater role in global healthcare delivery due to limited healthcare accessibility. The advent of innovative communication technologies has made it easier for patients to get services like health assessment, diagnosis, interventions, supervision, and information remotely. Digital imaging, decision support software, virtual reality, machine learning for error reduction, Internet of Things (IoT) such as wearable sensors, assistive robots, advances in data management (tracking, transmission, and storage), real-time analytics or store-and-forward, are some of the dynamic technologies that provide strong evidence-based support to scalable and sustainable telehealth programs.

Confident But Lacking Support: School Librarians And Students With Autism, Amelia Anderson, Selena Layden

STEMPS Faculty Publications

School librarians work with students across their organizations, including those with disabilities such as autism spectrum disorder (ASD). However, little is known about how prepared school librarians are to serve these students. Using a mixed-methods survey, this study sought to explore training school librarians have taken about ASD and students with disabilities, as well as the effects of training on librarian confidence and library services. Based on results, librarians who received training through their school district or professional development outside of coursework reported being more confident in supporting students with ASD in the school library.

Advancing Cyanobacteria Biomass Estimation From Hyperspectral Observations: Demonstrations With Hico And Prisma Imagery, Ryan E. O'Shea, Nima Pahlevan, Brandon Smith, Mariano Bresciani, Todd Egerton, Claudia Giardino, Lin Li, Tim Moore, Antonio Ruiz-Verdu, Steve Ruberg, Stefan G.H. Simis, Richard Stumpf, Diana Vaičiūtė

Biological Sciences Faculty Publications

Retrieval of the phycocyanin concentration (PC), a characteristic pigment of, and proxy for, cyanobacteria biomass, from hyperspectral satellite remote sensing measurements is challenging due to uncertainties in the remote sensing reflectance (∆R_rs) resulting from atmospheric correction and instrument radiometric noise. Although several individual algorithms have been proven to capture local variations in cyanobacteria biomass in specific regions, their performance has not been assessed on hyperspectral images from satellite sensors. Our work leverages a machine-learning model, Mixture Density Networks (MDNs), trained on a large (N = 939) dataset of collocated in situ chlorophyll-a concentrations (Chla), …

Self And Microbiota-Derived Epitopes Induce Cd4⁺ T Cell Anergy And Conversion Into Cd4⁺Foxp3⁺ Regulatory Cells, Michal P. Kuczma, Edyta A. Szurek, Anna Cebula, Vu L. Ngo, Maciej Pietrzak, Piotr Kraj, Timothy L. Denning, Leszek Ignatowicz

Biological Sciences Faculty Publications

The physiological role of T cell anergy induction as a key mechanism supporting self-tolerance remains undefined, and natural antigens that induce anergy are largely unknown. In this report, we used TCR sequencing to show that the recruitment of CD4⁺CD44⁺Foxp3⁻CD73⁺FR4⁺ anergic (Tan) cells expands the CD4⁺Foxp3⁺ (Tregs) repertoire. Next, we report that blockade in peripherally-induced Tregs (pTregs) formation due to mutation in CNS1 region of Foxp3 or chronic exposure to a selecting self-peptide result in an accumulation of Tan cells. Finally, we show that microbial antigens from Akkermansia muciniphila …

Interaction Between Genetic Risk Scores For Reduced Pulmonary Function And Smoking, Asthma And Endotoxin, Sinjini Sikdar, Annah B. Wyss, Mi Kyeong Lee, Thanh T. Hoang, Marie Richards, Laura E. Beane Freeman, Christine Parks, Peter S. Thorne, John L. Hankinson, David M. Umbach, Alison Motsinger-Reif, Stephanie J. London

Mathematics & Statistics Faculty Publications

Rationale Genome-wide association studies (GWASs) have identified numerous loci associated with lower pulmonary function. Pulmonary function is strongly related to smoking and has also been associated with asthma and dust endotoxin. At the individual SNP level, genome-wide analyses of pulmonary function have not identified appreciable evidence for gene by environment interactions. Genetic Risk Scores (GRSs) may enhance power to identify gene–environment interactions, but studies are few.

Methods We analysed 2844 individuals of European ancestry with 1000 Genomes imputed GWAS data from a case–control study of adult asthma nested within a US agricultural cohort. Pulmonary function traits were FEV₁, …

Medullary Thyroid Carcinoma In King Chulalongkorn Memorial Hospital: Natural History, Management, And Outcome, Natawat Narueponjirakul, Pasurachate Samorn

Chulalongkorn Medical Journal

Background: Medullary thyroid carcinoma (MTC) is rare and a diagnosis difficulty disease. In term of natural history, management, and outcomes among Thai patients, the data were scarce. Objectives: We aimed to review natural history, management, and clinical outcome of MTC patients in the tertiary care hospital.Methods: Retrospective study of medullary thyroid carcinoma patient was performed in our hospital from January 1, 2002 to December 31, 2011. Medical records has been carefully reviewed. Demographic data, clinical presentation, investigation, management and outcomes has been collected.Results: Sixteen MTC patients were taken into account for 1.1% of all thyroid carcinoma of the hospital, 12 …

Advantage Of Digital Breast Tomosynthesis Combined With Standard Digital Mammography Over Standard Digital Mammography Alone In Surveillance For Local Recurrent Breast Cancer In Patients With Breast Conservative Treatment, Somchanin Pipatpajong, Sarunya Poopongpanich

Chulalongkorn Medical Journal

Background: Although breast conserving therapy (BCT) offers more advantages in addition to the competitive survival rate over the traditional treatment of mastectomy, post-BCT surveillance for cancer recurrence remains challenging.Objectives: The purpose of this study was to compare rates of indeterminate findings of standard digital mammography (DM) plus digital breast tomosynthesis (DBT) and DM alone in patients who had undergone BCT at King Chulalongkorn Memorial Hospital, Bangkok, Thailand.Methods: We retrospectively enrolled 150 post-BCT patients who had regular follow-up visits for cancer surveillance by radiological imaging at least for two years at the hospital from January 1, 2013 to December 31, 2014. …

Surgical Management Of Anorectal Malformations Based On Krickenbeck Classification: 13 - Year Experience From A Single Institute, Sirima Liukitithara, Katawaetee Decharun, Paisarn Vejchapipat, Somboon Roekwibunsri, Dusit Viravaidya, Prapapan Rajatapiti, Soottiporn Chittmittrapap

Chulalongkorn Medical Journal

Background: Anorectal malformations (ARMs) represent a wide spectrum of disease with various operative managements. Posterior sagittal anorectoplasty (PSARP) has been developed as the standard technique. However, there are still controversies in the management of ARMs.Objectives: The objective of this study was to assess the operative managements including associated anomalies and functional outcome of anorectal malformations at King Chulalongkorn Memorial Hospital over a 13-years.Methods: A retrospective study was conducted at King Chulalongkorn Memorial Hospital between January 2004 and December 2016. Patients’ information was classified based on Krickenbeck classification. Statistical analysis was performed using IBM SPSS statics 22.0 version for MAC.Results: A …