Medicine and Health Sciences Commons^™

Efficacy Of The In Vitro Splitting Of Human Preimplantation Embryos From Art Programs, Marjan Omidi, Mohammad Ali Khalili, Azam Agha-Rahimi, Stefania Nottola, Fatemeh Anbari, Azita Faramarzi, Maria Grazia Palmerini

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to evaluate the efficiency of in vitro embryo splitting (IES) procedures. We also assessed the quality of the blastocysts developed from embryos obtained from different sources. Materials and methods: Good quality embryos at 6-8-cell stages were categorized according to their fertilization sources: 1) frozenwarmed donated embryos, 2) chromosomally abnormal embryos, 3) parthenogenetic embryos, and 4) embryos derived from fertilization of in vitro matured oocytes (rescue IVM). After IES, splitting and developmental efficiency was assessed. Furthermore, the quality of the developed blastocysts was evaluated by Hoechst and propidium iodide (PI) staining. Results: The data …

Family-Centeredness Of Services For Young Children With Down Syndrome: Anobservational Study From Turkey, Emi̇ne Bahar Bi̇ngöler Pekci̇ci̇, Ezgi̇ Özalp Akin, Funda Akpinar, Gamze Hayran, Cansu Keleş, Betül Yağbasan, Nazmi̇ye Kurşun, İlgi̇ Ertem

Turkish Journal of Medical Sciences

Background/aim: Physicians require information on the family centeredness of services for children with Down syndrome, one of the most frequently encountered disabilities in childhood. We aimed to determine the family-centeredness of services for young children with Down syndrome and using a bioecological theory framework we hypothesized that child, family and service-related factors would be associated with such services. Materials and methods: In a crosssectional design, children with Down syndrome seen at Ankara University Developmental Pediatrics Division (AUDPD) between February 2020 and June 2020 were included if they had received services in the community for at least 12 months. Mothers responded …

Genetic Variation In The Bovine Myogenic Determination Factor 1 (G.782g>Apolymorphism) And Its Influence On Carcass Traits In Turkish Grey Steppe Cattle, Sena Ardiçli, Özden Çobanoğlu

Turkish Journal of Veterinary & Animal Sciences

MyoD1 gene is a member of the myogenic differentiation gene family, which plays a crucial role in growth and development. There is a lack of information about the MyoD1variants and their phenotypic influences in Turkish Grey Steppe cattle. Therefore the present study aimed to determine the genetic variability of MyoD1 g.782G>A polymorphism and to evaluate its effects on carcass characteristics in Turkish Grey Steppe cattle. Analyses were conducted on a total of 142 Turkish Grey Steppe bulls. The PCR-RFLP technique was used for genotyping of the g.782G>A polymorphism in exon 1 of the MyoD1 gene. The population genetic …

Effect Of Neem (Azadirachta Indica) And Tulsi (Ocimum Sanctum) Leaves Powder Ongrowth Performance, Hemato-Biochemical Profile And Carcass Traits Of Japanese Quail (Coturnix Japonica), Luqman Arshad, Syed Zeeshan Haider Naqvi, Jibran Hussain, Hala Naeem, Saima Shahzad, Amna Aslam, Abd Ur Rehman, Abdul Ghayas

Turkish Journal of Veterinary & Animal Sciences

The current research investigated the growth performance, hematology, serum biochemistry of Japanese quails fed Neem (Azadirachta indica) and Tulsi (Ocimum sanctum) leaves powder with basic diet. A total number of 300 one-week old Japanese quail chicks were divided randomly into four dietary treatments with five replicates each (15 birds per replicate). Dietary treatments were: T0 or control or basal diet, T1 (Neem 0.5%), T2 (Tulsi 1%) and T3 (Neem 0.25% + Tulsi 0.5%) in basal diet. Growth performance parameters (feed intake, body weight, weight gain and feed conversion rate) were determined weekly. Hematology, serum biochemistry, carcass traits were evaluated on …

Leukocyte Esterase Reagent Strips: Rapid, Economical And Reliable Cow Side Test Forsubclinical Endometritis, Arshaq Asfar, Khursheed Ahmad Sofi, Mudasir Ahmad Bhat, Abrar Ahad Malik, Asloob Ahmad Malik

Turkish Journal of Veterinary & Animal Sciences

This study was carried out in crossbred cows (>60 DIM) to evaluate leukocyte esterase (LE) strip test, protein strip test, pH strip test, white side test (WST) of estrual mucus, in comparison to endometrial cytology (EC) using cytobrush (CB) as reference diagnostic method for subclinical endometritis (SCE). Endometrial cytology was done in 78 cows with ≥4% PMNs as cut-off value for SCE. Leukocyte esterase strip test was done by contacting estrual mucus with multireagent urinalysis reagent strips and results recorded after 10 min. Similarly, protein and pH strip tests were conducted using the same strips and results recorded after …

A Research On Babesia And Theileria Species In Sheep And Goats Of Kırıkkale Provincethrough Molecular Methods, Sami̇ Gökpinar, Aycan Nuri̇ye Gazyağci, Meral Aydeni̇zöz, Ufuk Kaya

Turkish Journal of Veterinary & Animal Sciences

The aim of the present study was to determine presence and prevalence of Babesia and Theileria species in the sheep and goats of stock farming in the province of Kırıkkale, which is in Central Anatolia Region of Turkey through microscopic examination and RLB method. Venous blood samples of 3 mL were collected from vena jugularis of 300 sheep and 100 goats into tubes containing EDTA. Blood smears were prepared from samples; and stained by Giemsa and examined for Theileria and Babesia under a light microscope. Genomic DNAs were extracted from blood samples with EDTA through suitable methods; a region with …

Melatonin Has Favorable Preventive Effects On Experimental Chronic Pancreatitis Rat Model, Esra Guzel Tanoglu, Alpaslan Tanoğlu, Makbule Çi̇sel Aydin Meri̇çöz, Muhammed Fevzi̇ Esen

Turkish Journal of Medical Sciences

Background/aim: Currently, there is not any specific treatment for chronic pancreatitis (CP). It was aimed to investigate the effects of melatonin administration on endoplasmic reticulum (ER) stress, oxidative stress, fibrosis, biochemical and histopathological parameters, and Abcc2,Abcc5, and Abcg2 gene levels in an experimental rat CP model. Materials and methods: Forty rats were randomized into five groups: Sham, CP, CP+25 mg/kg melatonin, CP+50 mg/kg melatonin, and CP+placebo. In all rats, except the sham group, a model of chronic pancreatitis was accomplished with intraperitoneal caerulein administration. In treatment groups, melatonin was used as a therapeutic agent. Serum TGF-ß, TNF-α, MDA and GPx …

Cardiovascular Effects Of Transcranial Direct Current Stimulation And Bimanual Training In Children With Cerebral Palsy, Manda L. Keller-Ross, Daniel P. Chantigian, Samuel Nemanich, Bernadette T. Gillick

Occupational Therapy Faculty Research and Publications

Purpose:

To determine the influence of combined transcranial direct current stimulation (tDCS) to the motor cortex (M1) and bimanual training on cardiovascular function in children with cerebral palsy (CP).

Methods:

Mean arterial pressure (MAP), heart rate (HR), and HR variability (HRV) were measured immediately before and after 20 minutes of cathodal tDCS to contralesional M1 and bimanual training on days 1, 6, and 10 of a 10-day trial in 8 participants (5 females, 7-19 years).

Results:

Baseline MAP and HR were similar across days (93 ± 10 mm Hg and 90 ± 10 bpm, P > .05). MAP was similar from …

An Ethical Market For Kidney?, Sang T. Truong

Student Research

The kidney performs several vital functions that maintain our general health condition, including filtering waste chemicals out of our blood. Kidney failure is a condition where patients’ kidneys lose their ability to filter the waste from their blood, leading to accumulating toxin in their body. Without any medical care, a patient with kidney failure has a couple days to a couple of weeks to live. One way to elongate the life of the kidney-failure patient is through kidney transplant, where another kidney is implanted into the patient’s body.

In the U.S, it is illegal to trade a kidney for money. …

How To End Our Stories: A Study Of The Perspectives Of Seniors On Dementia And Decision-Making, James Toomey

Elisabeth Haub School of Law Faculty Publications

Because dementia can cause individuals to make decisions that they otherwise would not, the law needs a mechanism to determine which decisions are entitled to the respect of the legal system and which may be overridden by others. In the philosophical literature, three primary theories for how to make this determination have been offered. First, "Cognitivism" posits that whether a decision should be recognized is a function of the mechanical functioning of the individual's brain at the time the decision is made. Second, "Essentialism" holds that decisions should be recognized so long as they are consistent with the cluster of …

1 Long Term Impact Of Microimplant Assisted Rapid Palatal Expansion On Soft Tissue Nasal Morphology, Laura Chew, Heeyeon Suh, Joorok Park, Heesoo Oh

Orthodontics and Endodontics Theses

Introduction: When skeletal transverse discrepancies exist between the maxilla and mandible, they commonly manifest in dental malocclusion. If left uncorrected, the malocclusion can lead to periodontal issues, tooth fractures, tooth loss, or other significant dental problems. Utilization of microimplants in palatal expansion aims to correct transverse discrepancies between the maxilla and mandible by separating the palatal suture in a parallel manner aimed at maximizing skeletal changes and minimizing dental side effects. Overlying soft tissue changes can be affected by the induced skeletal changes. The purpose of this study is to evaluate skeletal expansion and the overlying soft tissue change that …

Evaluation Of Time-Dependent Camber And Deflections In Bridge Girders, Furkan Cakmak

Wayne State University Theses

A methodology to predict each stage of camber and displacements in composite prestressed concrete and steel bridge superstructures from inception to end of service life including a prediction of rebound in deck replacement projects is presented. The methodology invokes the use of multiple creep curves and allows the proper simulation of various construction activities each of which feature unique loading events. The proposed method captures the influence of several factors, such as creep and shrinkage of beam and deck concrete as well as prestresses losses induced because of these phenomena. Additionally, the prediction methodology offers the capability to quantify the …

Oral Cbd Administration: Assessing Bioavailability And Behavioral Outcomes In A Rodent Model, Jordan Skully

Wayne State University Theses

There has been a recent surge in popularity for cannabidiol (CBD), a major non-psychotropic constituent of cannabis, due to numerous claims of potential therapeutic properties, which include, but are not limited to, anxiolytic, antinociceptive, and anti-inflammatory effects. However, as previous scientific literature on CBD's effectiveness in providing such therapeutic effects is limited, this project was aimed to evaluate the potential beneficial properties of a hemp derived 99% pure CBD compound provided from Ellipse Analytics (Denver, CO) in a rodent model. We analyzed the pharmacokinetics of this CBD product as well as the behavioral outcomes after acute and chronic administration. Pharmacokinetics …

The Changes In Dietary Patterns Of Saudi Women Residing In Saudi Arabia, South Korea, And The United States: The Effects Of Length Of Residency On Dietary Acculturation, Nouf Alharbi

Wayne State University Dissertations

ABSTRACT

THE CHANGES IN DIETARY PATTERNS OF SAUDI WOMEN RESIDING IN SAUDI ARABIA, SOUTH KOREA, AND THE UNITED STATES: THE EFFECTS OF LENGTH OF RESIDENCY ON DIETARY ACCULTURATION

by

NOUF ABDULLAH ALHARBI

August 2021

Advisor: Dr. Kai-Lin Catherine JenMajor: Nutrition & Food Science Degree: Doctor of Philosophy Given the large and growing numbers of Saudi individuals living abroad, examining how their dietary patterns have changed and influenced by acculturation with host countries, as well as the health consequences of these changes is a research area that needs to be investigated. The primary objectives of the present study were to compare …

Association Of In‐Line Digestive Enzyme Cartridge With Enteral Feeds On Improvement In Anthropometrics Among Pediatric Patients With Cystic Fibrosis, Karyn Shaw, Stacie Hunter, Minjae Lee, Meghana Sathe

2021

No abstract provided.

Dietary Management Of A 7-Year-Old Boy With S-Adenosylhomocysteine Hydrolase (Sah) Deficiency, Page Meachum, Garrett Gotway

2021

No abstract provided.

A Brief Review Of Fda’S Novel Tools For Ensuring Pharmaceutical Quality In The Human Drug Supply Chain, Heather R. Campbell, Robert A. Lodder

Pharmaceutical Sciences Faculty Publications

Purpose

Pharmaceutical manufacturers execute quality control operations and Good Manufacturing Practices (GMP) to provide safe drugs. The Federal Drug and Food Administration (FDA) is tasked with ensuring manufacturers are performing such procedures. Faced with limited resources the FDA has developed novel tools to aid pharmaceutical manufacturing oversight. This paper briefly reviews these tools.

Methods

Current inspection approaches employed by the FDA are identified by searching the FDA’s guidances, the Code of Federal Regulations, public reports and other online resources.

Outcomes

Industry

A risk-based site selection model (SSM) is used to prioritize on-site inspections for FDA investigators. Theoretically, the SSM allows …

Sexual Behaviour Patterns And Sti Risk: Results Of A Cluster Analysis Among Men Who Have Sex With Men In Portugal, Karel Blondeel, Sonia Dias, Martina Furegato, Armando Seuc, Ana Gama, Ricardo Fuertes, Luís Mendão, Marleen Temmerman, Igor Toskin

Obstetrics and Gynaecology, East Africa

Objectives: Portugal has the highest HIV incidence rate in Western Europe. The proportion assigned to sexual contact between men recently increased to more than 30% of all HIV infections. Men who have sex with men (MSM) are vulnerable to the acquisition of other sexually transmitted infections (STIs), increasing the per-contact risk of HIV infection. Building on syndemic theory, the aim of this analysis was to identify patterns of current sexual behaviour in MSM, and explore their relationship with self-reported current, past STI diagnoses and HIV positive serostatus.

Design: A cross-sectional behavioural survey was conducted in Portugal among MSM, using a …

Solving The Continual Improvement And Innovation Challenge For The Benefit Of Patients: How An Effective Pharmaceutical Quality System (Pqs) And Risk-Based Approach Could Transform Post-Approval Change (Pac) Management, Emabelle Ramnarine

Dissertations

Patients deserve their medicines on time every time. Regulators safeguard public health by ensuring availability of safe, effective, high-quality medicines. Pharmaceutical companies must continually improve and innovate to deliver such medicines. In spite of these patient-centric objectives, drug shortages have continued to grow as a global public health concern. The drug shortage problem has existed for decades though there has been no shortage of effort, recommendations, papers, and expectations to resolve it. During the ongoing COVID-19 pandemic even exceptional measures were rapidly implemented to prevent shortages, yet no long-term solutions have been found.

This research hypothesis was that due to …

Sure 2021 Undergraduate Science Conference Booklet, Sure Network

Group Reports

The SURE 2021 Conference was the fourth series of Science Undergraduate Research Experience (SURE) Conferences and second online conference, following earlier face to face series in 2018 (with three conferences in Dublin, Athlone and Waterford) and in 2019 (with three conferences in Dublin, Sligo and Carlow). The 2021 virtual online conference was hosted by Waterford Institute of Technology (WIT), TUS:MM (Athlone Institute of Technology) and Dundalk Institute of Technology (Dundalk IT) and featured 23 oral presentations and 48 poster presentations across three thematic streams/break out rooms on zoom. An interactive virtual poster session took place using …

Quantifying The Training And Match-Play External And Internal Load Of Elite Gaelic Football Players, Shane Malone, Kieran Collins, Allistair Mcrobert, Dominic Doran

Articles

The current investigation quantified the training and match-play load of elite Gaelic football players across a two-season period using global positioning system technology (GPS), rating of perceived exertion (RPE) and sessional rating of perceived exertion (sRPE). Total weekly workload variables were collected across GPS, RPE, and sRPE across thirty-six elite Gaelic footballers (mean ± SD, age: 26 ± 5 years; height: 177 ± 8 cm; mass: 81 ± 7 kg) from one elite squad during a two-season observational period. External training load variables included: Total distance (m), High speed running (m; ≥ 17.1 km·h −1 ), Sprint distance (m; 22 …

A Comparison Of Anthropometric And Performance Profiles Between Elite And Sub-Elite Hurling Players, John Keane, Shane Malone, Ciaran Keogh, Damian Young, Guiseppe Coratella, Kieran Collins

Articles

The aim of the current study was to identify the specific differences in anthropometric and performance profiles between elite and sub-elite hurling players with respect to position and level of play. One hundred and thirty-seven (n = 137) hurlers at the elite (n = 61) and sub-elite (n = 76) level completed a series of anthropometric [height, body mass, the sum of seven skinfolds, adipose tissue percentage estimates (%AT), fat-free mass estimations (FFM)) and performance ((countermovement jump height (CMJ), CMJ peak power (CMJ PP), CMJ relative peak power (CMJ RPP), acceleration (5, 10 and 20 m), and yo-yo intermittent recovery …

Running Your Best Triathlon Race, Naroa Etxebarria, Jackson Wright, David Pyne, Christian Mesquida, Hamish Jeacocke

Articles

Negative or evenly paced racing strategies often lead to more favorable performance outcomes for endurance athletes. However, casual inspection of race split times and observational studies both indicate that elite triathletes competing in Olympic-distance triathlon typically implement a positive pacing strategy during the last of the 3 disciplines, the 10-km run. To address this apparent contradiction, the authors examined data from 14 International Triathlon Union elite races over 3 consecutive years involving a total of 725 male athletes. Analyses of race results confirm that triathletes typically implement a positive running pace strategy, running the first lap of the standard 4-lap …

Developing A Framework For Professional Practice In Applied Performance Analysis, Denise Martin, Peter G. O'Donohoghue, Jonathan Bradley, Denise Mcgrath

Articles

Applied performance analysts are increasingly seen as sports science professionals; however, there is no accepted framework for professional practice. The purpose of this study is to develop and validate a framework for professional practice in applied performance analysis (PA) which identifies the components of practice and the expertise underpinning it.

A six-step framework analysis was conducted: (1) An initial conceptual framework was devised based on well-accepted components of applied practice; (2) A systematic review identified 90 papers relating to applied PA practice; (3) Papers were coded to the initial framework and additional themes recorded; (4) Themes were analysed and synthesised …

Pediatric Emergency Department Nurse’S Knowledge And Attitudes Of Pediatric Fluid Resuscitation, Tannah Kimberly O'Brien, Kerry Nolte Phd, Fnp-C, Denise Downey Msn, Rn-Bc, Cpen, Debra Lajoie Jd, Phd, Msn, Rn, Esq., Allison Ivers Msn, Rn, Cnl, Kathleen Sultan Bsn, Rn, Cpen

Honors Theses and Capstones

Background: Rapid fluid resuscitation is essential to the management of pediatric shock, but there are many barriers to published guideline adherence. Limited evidence describing emergency department (ED) nurse’s knowledge and attitudes of fluid resuscitation exists. This study described pediatric ED nurse’s knowledge and attitudes of fluid resuscitation.

Methods: This single-site descriptive study used survey methodology. A 23-question survey was distributed to nurses in the ED at Boston Children’s Hospital. The survey measured nurse’s knowledge, attitudes, and perceived barriers to fluid resuscitation.

Results: Findings suggested gaps found between actual and perceived knowledge consistent with prior evidence. There was a 50.9% response …

A Critical Review Of Apraxia Of Speech And Childhood Apraxia Of Speech, Madison Joan Smith

Honors Theses and Capstones

The theories and neural bases of Apraxia of Speech (AOS) have long been debated. In 1861, Paul Broca identified two patients with speech/language impairments who became the basis for the theory on aphemia, now known as apraxia. Broca noted of patients with AOS that “there are cases in which the general faculty for language remains unaltered; where the auditory apparatus is intact; where all muscles—including those of speech and articulation—are under voluntary control; and where nevertheless, a cerebral lesion abolishes articulated language” (Broca, 1861/2000). The term “apraxia” was first introduced by Hugo Liepmann in 1908 and was described as “the …

Orthostatic Headaches Associated With Spontaneous Intracranial Hypotension And Autonomic Dysfunction-A Case Series In Young Patients, Ankita Ghosh, Yen X Tran, Leon Grant, Mohammed T Numan, Rajan Patel, Ian J Butler

Faculty, Staff and Student Publications

Background: Orthostatic headaches can be noted in spontaneous intracranial hypotension and orthostatic intolerance. We present a case series of young patients diagnosed with spontaneous intracranial hypotension and were treated for the same but subsequently developed orthostatic intolerance. Methods: We retrospectively reviewed charts for seven young patients with orthostatic headaches related to spontaneous intracranial hypotension and orthostatic intolerance. Results: Patients were diagnosed with spontaneous intracranial hypotension. Diagnosis was confirmed by identifying epidural contrast leakage and three of seven patients were noted to have early renal contrast excretion on computerized tomography myelography. Patients were treated with epidural blood patches. All patients showed …

Zilpaterol And Ractopamine: Reaching Consensus On Trace-Level Transfers To Racehorses, Jacob Machin, Kimberly Brewer, Clara K. Fenger, Sarah White-Springer, Abelardo Morales-Briceno, Thomas Tobin

Maxwell H. Gluck Equine Research Center Faculty Publications

In this article, we review the investigation of trace amounts of b-2 adrenergic agonists, a drug class that possess significant risk to the integrity of horse racing whether intentionally used or through the inadvertent contamination of feed.

Development Of An Integrated Medical And Behavioral Health Care Model For Children In Foster Care: The Rees-Jones Center For Foster Care Excellence, Kimberly Stone, Sara Moore, Sara Pollard

Integrated, Trauma-Informed Care

Children in foster care are classified as a population with special health care needs. They face multiple adverse childhood experiences and disrupted relationships, yet face barriers accessing consistent, high-quality health care. The American Academy of Pediatrics recommends integrated physical and behavioral health care for children in foster care, but little is known about the implementation of integrated care for this population. As a pediatrician, doctor of nursing practice, and psychologist in an academic medical setting, we describe the development and implementation of the Rees-Jones Center for Foster Care Excellence, emphasizing the role of medical and behavioral health providers in promoting …

Just Plain Dumb?: How Digital Contact Tracing Apps Could’Ve Worked Better (And Why They Never Got The Chance), Brian E. Ray

Law Faculty Articles and Essays

This essay describes how the privacy debate that emerged over digital contact tracing and Google’s and Apple’s decisions to strictly limit apps permitted to use their platforms resulted in undercutting their potential usefulness as a tool to combat the pandemic while still failing to engender trust in these tools as intended.