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2021

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Articles 16411 - 16440 of 21406

Full-Text Articles in Medicine and Health Sciences

Effectiveness Of Collaborative Handwriting Curriculum: Handwriting Without Tears And Orton-Gillingham, In Kindergarten Classroom Setting., Merry G. Harper Jan 2021

Effectiveness Of Collaborative Handwriting Curriculum: Handwriting Without Tears And Orton-Gillingham, In Kindergarten Classroom Setting., Merry G. Harper

Occupational Therapy Doctorate Capstone Projects

Background: Formal handwriting instruction, using evidence-based, developmentally appropriate handwriting programming, in school based occupational therapy is necessary to support the role of a student. Handwriting is an occupation of children in the school environment. Without formal handwriting instruction in place there is evidence to support occupational therapy intervention providing a handwriting program can improve handwriting success.

Purpose: The purpose of this research study is to determine the clinical efficacy of a hybrid approach to handwriting instruction pairing the Handwriting Without Tears and Orton-Gillingham instructional programming for prewriting and handwriting skills in the kindergarten population. The research question addressed is: Will …


Does Pre-Operative Education Increase Activity Participation And Decrease Perceived Arm Dysfunction In Breast Cancer Patients?, Stephanie R. Rexing Jan 2021

Does Pre-Operative Education Increase Activity Participation And Decrease Perceived Arm Dysfunction In Breast Cancer Patients?, Stephanie R. Rexing

Occupational Therapy Doctorate Capstone Projects

Executive Summary

Background: Currently there is sufficient evidence indicating safety with upper extremity resistive exercise among those at risk for developing breast cancer related lymphedema. However, there is insufficient evidence of the benefits of pre-operative lymphedema prevention education, upper body strengthening exercises, and strategies to continue or resume physically demanding activities that breast cancer survivors need to do, want to do, or are expected to do.

Purpose: This project described the impact pre-operative education has on activity participation, and perceived upper extremity function among individuals diagnosed with breast cancer compared to those who do not receive pre-operative education. The capstone …


Kindness As An Intervention For Student Social Interaction Anxiety, Resilience, Affect, And Mood: The Kiss Of Kindness Study Ii, Katie Shillington, Andrew Johnson, Tara Mantler, Shauna Burke, Jennifer Irwin Jan 2021

Kindness As An Intervention For Student Social Interaction Anxiety, Resilience, Affect, And Mood: The Kiss Of Kindness Study Ii, Katie Shillington, Andrew Johnson, Tara Mantler, Shauna Burke, Jennifer Irwin

Health Studies Publications

No abstract provided.


Cannabidiol: An Adjunctive Therapy To Risperidone For Autistic Children Experiencing Behavioral Outbursts, Cherie Dowell Jan 2021

Cannabidiol: An Adjunctive Therapy To Risperidone For Autistic Children Experiencing Behavioral Outbursts, Cherie Dowell

Physician Assistant Scholarly Project Posters

The purpose of this systemic literature review was to evaluate the safety, efficacy, and tolerability of medical cannabis in the treatment of aggression, irritability, and self-injurious behaviors in autistic children that are currently receiving risperidone. For this literature review, DynaMed, Cochrane, PubMed, ClinicalKey, and CINAHL were searched using various keywords and phrases. Studies that were included in this review were published after 2005, were peer-reviewed, and included systemic reviews, journal articles, clinical trials, randomized control trials, and meta-analyses. Studies that did not directly discuss autism and behavioral issues; autism treatment with risperidone, medical cannabis, or cannabidiol; that did not specifically …


Comparison Of Functional Capacity And Outcomes Of Patients With Rotator Cuff Injury: Surgery Versus Non-Invasive Methods, Brian Schiller Jan 2021

Comparison Of Functional Capacity And Outcomes Of Patients With Rotator Cuff Injury: Surgery Versus Non-Invasive Methods, Brian Schiller

Physician Assistant Scholarly Project Posters

Rotator cuff tears are acute or chronic tears of one or more of four specific muscles that encompass the glenohumeral joint. These tears can cause pain, decrease range of motion, and affect an individual for many years if not treated appropriately. The purpose of this literature review is to assess the most appropriate means of treatment between surgery, physical therapy, and injection therapies. The literature review was performed using electronic search databases CINAHL, PubMed, Clinical Key, Cochrane Library, Embase, SPORTDiscus and Research Gate.Studies were included if they directly evaluated the efficacy of surgical rotator cuff methods, physical therapy, corticosteroid injections, …


Decreasing Suicidal Risks Among Military Veterans With Posttraumatic Stress Disorder Or Major Depression, Manpreet K. Sheabat Jan 2021

Decreasing Suicidal Risks Among Military Veterans With Posttraumatic Stress Disorder Or Major Depression, Manpreet K. Sheabat

Physician Assistant Scholarly Project Posters

Suicide is a major cause of death in US. Military personnel are at a higher risk of committing suicide compared to the general population. The risk is exacerbated by Posttraumatic Stress Disorder (PTSD) and major depression.

• Few reviews have explored the effects of the recommended psychotherapeutic interventions on suicidal ideations and suicide rates for these two disorders, focusing on the veteran population. To address this, a literature search was performed through electronic databases to identify appropriate journal articles.

• Treatment with CPT and PE for PTSD has been found effective in decreasing suicidal thoughts, intents, and attempts. On the …


Effect Of A Ketogenic Diet On Glycemic Control In Type 2 Diabetics, Steven Moore Jan 2021

Effect Of A Ketogenic Diet On Glycemic Control In Type 2 Diabetics, Steven Moore

Physician Assistant Scholarly Project Posters

With the increasing rate of patients diagnosed with type 2 diabetes mellitus (T2DM) and the serious complications associated with this disease, there continues to be controversy surrounding the most effective way to manage glycemic control in this population. The intention of this meta-analysis is to determine the effect of a ketogenic diet as a first-line treatment option on glycemic control in type 2 diabetic patients. Effectiveness was determined by comparing the ketogenic diet to other popular diets recommended to diabetics by practitioners following guidelines set forth by the American Diabetes Association. Several high-quality studies were selected utilizing PubMed, Dynamed plus, …


Comparing Outcomes Of Online Application Therapy Versus Standard Psychotherapy In Patients Suffering From Mental Illness, Jenna Zwiers Jan 2021

Comparing Outcomes Of Online Application Therapy Versus Standard Psychotherapy In Patients Suffering From Mental Illness, Jenna Zwiers

Physician Assistant Scholarly Project Posters

The purpose of this research was to determine the effectiveness of internet-delivered cognitive behavioral therapy (iCBT) in comparison to standard cognitive behavioral therapy in the treatment of depression and anxiety. The quality, safety, therapist-response, and cost of internetdelivered cognitive behavioral therapy was also studied. This review utilized multiple databases including PubMed, CINAHL, Clinical Key, Cochrane Review, and PsychINFO from 2015 to 2020. The literature reviewed consisted of peer-reviewed studies, randomized controlled trials, and systematic reviews. Sources that were excluded from the study included those prior to 2015, studies with small sample sizes, and those that involved children. Thirteen resources were …


Investigating The Relationship Between Gcase And Pathology In Parkinson’S Disease, Brenna Beezhold Jan 2021

Investigating The Relationship Between Gcase And Pathology In Parkinson’S Disease, Brenna Beezhold

Summer Research

  • Parkinson’s disease (PD) is the most common neurodegenerative movement disorder
  • Patients experience rigidity, tremor, and bradykinesia
  • Due to a loss of dopaminergic neurons in the substantia nigra
  • Accumulation of α-synuclein Lewy bodies
  • Genetic risks include: LRRK2 and GBA1
  • GBA1 is a mutation within gene coding for Gcase (Glucocerebrosidase) which is a lipid hydrolase within the lysosome, leading to a loss of function.
  • LRRK2 is a hyperactivation mutation in the region coding for the enzyme Leucine Rich Repeat Kinase 23


The Impacts Of Terrorism On Maternal Health In Afghanistan, Kyla Rocanello-Snow Jan 2021

The Impacts Of Terrorism On Maternal Health In Afghanistan, Kyla Rocanello-Snow

Global Sustainable Development Projects

Terrorism is both directly and indirectly harmful to maternal health. Terrorist attacks targeted at healthcare workers, hospitals and maternity wards are a direct impediment of maternal healthcare. Other terrorist activity and conflict produce overall instability, aggravating insecurity in the country. Attacks that disrupt functions within a community and a country at large indirectly impact maternal health as they target specific social determinants of health, including infrastructure for transportation, education, and healthcare. Terrorism and the influence of Islamic militia groups in Afghanistan continue to threaten the power and stability of the national government, making it difficult for policy enactment to improve …


Comprehensive Care: Harm Reduction And The Opioid Epidemic, Riley Tinlin Jan 2021

Comprehensive Care: Harm Reduction And The Opioid Epidemic, Riley Tinlin

Global Sustainable Development Projects

Comprehensive Care: Harm Reduction and the Opioid Epidemic aims to delve deeper into the realities of opioid addiction and assess proposed prevention strategies by acknowledging the driving factors (biological, psychological, and social) and consequences of opioid abuse. Intervention strategies are offered from various access points ranging from the federal to individual level. The research conducted has shown that all access points must be considered for the success of prevention and treatment efforts. The intent of this paper is to argue that the proposed strategies are necessary steps to be taken if the United Nations Sustainable Development Goals 3 (good health …


Shurooq, Shurooq, Brandi Kilmer, Sherianne Schow, Nicole Taylor, Sasha Sloan Jan 2021

Shurooq, Shurooq, Brandi Kilmer, Sherianne Schow, Nicole Taylor, Sasha Sloan

TSOS Interview Gallery

Shurooq fled Iraq and came to the United States when she was 12. Iraq was a beautiful place full of family and celebration. Her brother passed away from leukemia 1 1/2 years prior to coming to the States. Prior to his death, their father took him to Syria to for treatment. He passed in Syria. Although the family had applied for a medical visa to the United States, upon Shurooq’s brother’s passing, they received threats and knew they could not stay. The call came for the visa and all but her mother were able to come. Thankfully her mother arrived …


Nuclear Factor Kappa-B Contributes To Cigarette Smoke Tolerance In Pancreatic Ductal Adenocarcinoma Through Cysteine Metabolism, Venugopal Gunda, Yashpal S Chhonker, Nagabhishek Sirpu Natesh, Pratima Raut, Sakthivel Muniyan, Todd A. Wyatt, Daryl J. Murry, Surinder K. Batra, Satyanarayana Rachagani Jan 2021

Nuclear Factor Kappa-B Contributes To Cigarette Smoke Tolerance In Pancreatic Ductal Adenocarcinoma Through Cysteine Metabolism, Venugopal Gunda, Yashpal S Chhonker, Nagabhishek Sirpu Natesh, Pratima Raut, Sakthivel Muniyan, Todd A. Wyatt, Daryl J. Murry, Surinder K. Batra, Satyanarayana Rachagani

Journal Articles: Environmental, Agricultural & Occupational Health

BACKGROUND: Retrospective studies revealed that cigarette smoking enhances risk of incidence and worsens prognosis in pancreatic cancer (PC) patients. Poor prognosis in smoker cohort of PC patients indicates prevalence of cigarette smoke stimulated survival mechanisms yet to be explored in PC. In this study, cigarette smoke induced metabolic pathways were explored and targeted in PC.

METHODS: Human pancreatic ductal adenocarcinoma cell (PDAC) lines, genetically engineered mice models (GEMMs), mass spectrometry based heavy isotope-based metabolite analysis, cytotoxicity assays and Nuclear factor kappa-B (NF-kB) targeting were utilized in this study. Cigarette smoke extract (CSE) was prepared fresh each day by bubbling cell …


Himmelfarb Library Liaison Letter - January 2021, George Washington University, Himmelfarb Health Sciences Library Jan 2021

Himmelfarb Library Liaison Letter - January 2021, George Washington University, Himmelfarb Health Sciences Library

Himmelfarb Library Liaison Letters

No abstract provided.


Investigation Of A Sars-Cov-2 B.1.1.529 (Omicron) Variant Cluster - Nebraska, November-December 2021, Lauren Jansen, Bryan Tegomoh, Kate Lange, Kimberly Showalter, Jon Figliomeni, Baha Abdalhamid, Peter C. Iwen, Joseph R. Fauver, Bryan Buss, Matthew Donahue Jan 2021

Investigation Of A Sars-Cov-2 B.1.1.529 (Omicron) Variant Cluster - Nebraska, November-December 2021, Lauren Jansen, Bryan Tegomoh, Kate Lange, Kimberly Showalter, Jon Figliomeni, Baha Abdalhamid, Peter C. Iwen, Joseph R. Fauver, Bryan Buss, Matthew Donahue

Journal Articles: Epidemiology

The B.1.1.529 (Omicron) variant of SARS-CoV-2 (the virus that causes COVID-19) was first detected in specimens collected on November 11, 2021, in Botswana and on November 14 in South Africa;* the first confirmed case of Omicron in the United States was identified in California on December 1, 2021 (1). On November 29, the Nebraska Department of Health and Human Services was notified of six probable cases† of COVID-19 in one household, including one case in a man aged 48 years (the index patient) who had recently returned from Nigeria. Given the patient's travel history, Omicron infection was suspected. Specimens …


The Impact Of A Sleep Training Program For Night Nurse Shift Workers, Adelaide C. Durkin Jan 2021

The Impact Of A Sleep Training Program For Night Nurse Shift Workers, Adelaide C. Durkin

DNP Research Projects

Abstract Objectives: To evaluate the impact of the NIOSH training on sleep quality scores, determine the association between intention to perform sleep improvement strategies and sleep quality, and identify strategies, barriers, and facilitators for implementation among night nurse shift workers. Methods: A pre-test and post-test design was used. Data were collected electronically between September 2020 and February 2021 before and after online intervention (NIOSH training). Participants who met the inclusion criteria were night shift nurses who worked full time in a hospital setting in the midwestern and southern United States (N = 42). After screening for risk of sleep apnea, …


The Financial Reality Of A Career In Veterinary Medicine For Kentucky Residents, Shelby Ackermann Jan 2021

The Financial Reality Of A Career In Veterinary Medicine For Kentucky Residents, Shelby Ackermann

Mahurin Honors College Capstone Experience/Thesis Projects

The financial burden of a veterinary medical education continues to increase with rising tuition prices. According to the American Veterinary Medical Association, the average educational debt of a veterinary student graduating in 2020 was approximately $157,000 (Bain, 2020). Studies published by the Journal of the American Veterinary Medical Association suggest that suicide rates among veterinarians are higher than that of the general population and list debt as a primary contributing factor. The purpose of this project is to expose students to the financial reality of veterinary medicine, increase awareness of financial and career opportunities, and compile information gathered from interviews …


Community Health Workers And Covid-19 In New York State: Adaptable And Resilient, But Strained, Annis Golden, Amy Williams Jan 2021

Community Health Workers And Covid-19 In New York State: Adaptable And Resilient, But Strained, Annis Golden, Amy Williams

Understanding and eliminating minority health disparities in a 21st-century pandemic: A White Paper Collection

This report summarizes findings from an interview-based study conducted in October and November 2020, and inferences that may be drawn from those findings with respect to the contributions of CHWs to eliminating disparities in the impact of COVID-19, and resources needed by CHW-based programs going forward. Findings are reported in the following areas: New connection strategies with clients used by CHWs in response to physical distancing requirements, barriers to connections; new areas of support CHWs provided; socioemotional impact of the pandemic and adaptations on CHWs; resources needed going forward; CHW support for efforts to eliminate disparities in COVID-19 impact on …


Improving Contact Tracing In Minority Communities By Combating Misinformation And Distrust, Jason G. Randall, Dev Dalal, Aileen Dowden Jan 2021

Improving Contact Tracing In Minority Communities By Combating Misinformation And Distrust, Jason G. Randall, Dev Dalal, Aileen Dowden

Understanding and eliminating minority health disparities in a 21st-century pandemic: A White Paper Collection

The COVID-19 pandemic continues to challenge the global population as infection rates climb, and officials struggle to balance the need to slow the spread of COVID-19 but also open economies safely. The disproportionate impact of COVID-19 on minority communities has raised questions about the unique experiences of these communities in terms of not only becoming infected with COVID-19, but also mitigating its spread. Although contact tracing has been identified as an invaluable tool for managing community spread and supporting economic reopening, this is contingent, in part, upon compliance with contact tracer requests. In this study, we investigated how misinformation and …


The Impact Of Covid-19 On Minority Disparities In Sexual And Reproductive Health Care In New York State, Elise Andaya, Rajani Bhatia Jan 2021

The Impact Of Covid-19 On Minority Disparities In Sexual And Reproductive Health Care In New York State, Elise Andaya, Rajani Bhatia

Understanding and eliminating minority health disparities in a 21st-century pandemic: A White Paper Collection

This report presents the findings from a qualitative study of the impact of COVID-19 on the provision of sexual and reproductive health (SRH) care to minority groups in New York State from March to October 2020. Drawing on interview material with frontline SRH providers and advocates, we illustrate the deepening inequalities in access to, and quality of, SRH care during the first surge of the pandemic, as well as their implications for future policy and practice. Key findings include: 1) Negative birthing conditions experienced disproportionately by women most vulnerable to poor maternal and birth outcomes; 2) delays and avoidance of …


Identifying Critical Psychological Characteristics Related To Successful Performance As A Contact Tracer: A Job Analysis, Dev Dalal, Jason G. Randall Phd, Gabrielle Danna, Joshua Ash Jan 2021

Identifying Critical Psychological Characteristics Related To Successful Performance As A Contact Tracer: A Job Analysis, Dev Dalal, Jason G. Randall Phd, Gabrielle Danna, Joshua Ash

Understanding and eliminating minority health disparities in a 21st-century pandemic: A White Paper Collection

The COVID-19 pandemic highlighted the need for a massive workforce of contact tracers to help end the global pandemic. Rapidly accelerating the recruitment, selection, and training of contact tracers proved to be difficult due in part to the lack of a valid, structured, and systematic approach to hiring and training contact tracers. This demonstration presents the results of the first step in developing a systematic selection and training program: a worker-oriented job analysis of the contact tracer job. Using archival records and structured interviews with 15 subject matter experts, we identified 26 unique characteristics related to successful performance as a …


Capital Region Collaborative Community Survey Project To Document Disparate Impacts Of Covid-19, The Albany Minority Health Task Force, Lawrence Schell, Annis Golden, Alex Pieterse, Archana Krishnan, Masahiro Yamamoto, Elizabeth Holdsworth, Pallavi Khurana, Olivia Mata, Amy Williams, Hnin Wai Lwin Myo Jan 2021

Capital Region Collaborative Community Survey Project To Document Disparate Impacts Of Covid-19, The Albany Minority Health Task Force, Lawrence Schell, Annis Golden, Alex Pieterse, Archana Krishnan, Masahiro Yamamoto, Elizabeth Holdsworth, Pallavi Khurana, Olivia Mata, Amy Williams, Hnin Wai Lwin Myo

Understanding and eliminating minority health disparities in a 21st-century pandemic: A White Paper Collection

The Capital Region Collaborative Community Survey project was undertaken in December 2020- January 2021 to document the social, economic and health impacts of COVID-19 on residents in the Capital Region, particularly in the city of Albany with an emphasis on the impacts on Black and African American (B/AA) communities (n=239). Key findings included B/AA participants reported experiencing general racism or racial discrimination significantly more than other racial groups as did Hispanics. The pandemic impacted employment of Capital Region residents significantly as half of the respondents either lost their jobs or had their hours reduced. B/AA individuals were more likely than …


Food Insecurity In Ny State. Solutions To Address The Multifaceted Problem, Janine Jurkowski, Tomoko Udo, Angela Hackstadt Jan 2021

Food Insecurity In Ny State. Solutions To Address The Multifaceted Problem, Janine Jurkowski, Tomoko Udo, Angela Hackstadt

Understanding and eliminating minority health disparities in a 21st-century pandemic: A White Paper Collection

Food is an essential determinant of health; the challenges in meeting nutritional needs for all are complex. Food insecurity involves the availability of enough safe and nutritious food, having access to that food, and being able to effectively utilize that food for household consumption. Availability has to do with the supply chain, which is affected directly by the social and physical environment. Access is related to the social and economic factors that determine individuals and households’ socioeconomic opportunities. Utilization has to do with having the ability, storage and tools for food preparation. Food insecurity is a growing social problem with …


Closing The Health Disparity Gap In U.S. Immigrant Communities In The Era Of Covid-19: A Narrative Review, Dina Refki, Rukhsana Ahmed, Jeanette Altarriba Jan 2021

Closing The Health Disparity Gap In U.S. Immigrant Communities In The Era Of Covid-19: A Narrative Review, Dina Refki, Rukhsana Ahmed, Jeanette Altarriba

Understanding and eliminating minority health disparities in a 21st-century pandemic: A White Paper Collection

The COVID-19 pandemic continues to have significant impacts on social determinants of health. Immigrant communities often bear a disproportionate burden of the crisis because of the immigration experience, which serves as an additional social determinant of health. Evidence suggests that these communities are hard hit by economic instability, food insecurities, isolation, lack of safe housing and safe neighborhoods, environmental dynamics that cut them off from systems of support, lack of sufficient access to educational tools that have become critical in remote and digital learning, limited access to health and healthcare resources, low health literacy, and restricted access to culturally and …


Identifying Nontraditional Epidemic Disease Risk Factors Associated With Major Health Events From World Health Organization And World Bank Open Data, Roberta Lugo-Robles, Eric C. Garges, Cara H. Olsen, David Brett-Major Jan 2021

Identifying Nontraditional Epidemic Disease Risk Factors Associated With Major Health Events From World Health Organization And World Bank Open Data, Roberta Lugo-Robles, Eric C. Garges, Cara H. Olsen, David Brett-Major

Journal Articles: Epidemiology

Health events emerge from host, community, environment, and pathogen factors-forecasting epidemics is a complex task. We describe an exploratory analysis to identify economic risk factors that could aid epidemic risk assessment. A line list was constructed using the World Health Organization Disease Outbreaks News (2016-2018) and economic indicators from the World Bank. Poisson regression employing forward imputations was used to establish relationships with the frequency with which countries reported public health events. Economic indicators demonstrated strong performance appropriate for further assessment in surveillance programming. In our analysis, three economic indicators were significantly associated to event reporting: how much the country's …


Pediatric Caregiver Health Literacy: Comparing Perceptions Of Pediatricians And Nurse Practitioners, Kirbey Flora Jan 2021

Pediatric Caregiver Health Literacy: Comparing Perceptions Of Pediatricians And Nurse Practitioners, Kirbey Flora

Mahurin Honors College Capstone Experience/Thesis Projects

Throughout life, most people will interact with the healthcare system to manage information in order to make healthcare decisions. Health literacy is the ability to comprehend health information needed to make healthcare decisions. Pediatric patients often do not have a voice in their healthcare decisions; therefore, their health outcomes may be affected by the health literacy of their caregivers. In addition, the child’s health may be impacted by the ability of the healthcare team to provide appropriate health education. The purpose of this honors thesis was to determine pediatric healthcare providers’ perception of health literacy in their practices. Qualitative data …


Physiological Stability During Oral Feeding In Preterm Infants: Associations With Feeding Behaviors And Cues, Cindy M. Lund Jan 2021

Physiological Stability During Oral Feeding In Preterm Infants: Associations With Feeding Behaviors And Cues, Cindy M. Lund

Graduate Research Theses & Dissertations

The purpose of this study was to examine the relationship between measures of physiological stability/instability during feeding. An additional aim was to determine if behaviors associated with physiological stability were also perceived as readiness or stress cues. Participants included 5 preterm infants (<37 weeks gestation) with no craniofacial anomalies. Infants were videotaped when they were taking at least 90% of prescribed volume. This study analyzed the common behaviors seen in preterm infants during bottle feeding to determine if there were associations with measures of physiological stability. Behaviors were also analyzed to determine which were perceived as indicating stress or readiness to feed by novice observers. Coding was conducted offline using Noldus Observer software.

Results revealed a statistically significant relationship between behaviors classified as stress cues and HR instability. There was not a significant association between stress cues and RR or SPO2. Binomial testing identified specific preterm infant feeding behaviors that were more often classified as stress cues, with significance noted in audible swallow and vocalization. Several of the specific preterm …


Dnp Proposal: Implementing Staff Education To Reduce Stress And Increase Resiliency, Samantha Lambert, Mariana Corpus Jan 2021

Dnp Proposal: Implementing Staff Education To Reduce Stress And Increase Resiliency, Samantha Lambert, Mariana Corpus

Nursing DNP Projects

Problem: Increased stress and decreased resiliency are concerning concepts that continue to be common themes within nursing practice. Stress, compassion fatigue, and burnout among nurses pose a great risk to the health care system, the patients it serves, as well as the nurses. Persistent levels of high stress additionally impact work activities and job performance, leading nurses to experience burnout, compassion fatigue, lower job satisfaction, high workplace turnover, and poor quality of care for patients. Nurses who demonstrate resiliency can adapt to unexpected events with a positive attitude, self-esteem, and tolerance.

Purpose: To decrease stress levels and improve resiliency among …


Structure And Activity Of A Selective Antibiofilm Peptide Sk-24 Derived From The Nmr Structure Of Human Cathelicidin Ll-37, Yingxia Zhang, Jayaram Lakshmaiah Narayana, Qianhui Wu, Xiangli Dang, Guangshun Wang Jan 2021

Structure And Activity Of A Selective Antibiofilm Peptide Sk-24 Derived From The Nmr Structure Of Human Cathelicidin Ll-37, Yingxia Zhang, Jayaram Lakshmaiah Narayana, Qianhui Wu, Xiangli Dang, Guangshun Wang

Journal Articles: Pathology and Microbiology

The deployment of the innate immune system in humans is essential to protect us from infection. Human cathelicidin LL-37 is a linear host defense peptide with both antimicrobial and immune modulatory properties. Despite years of studies of numerous peptides, SK-24, corresponding to the long hydrophobic domain (residues 9–32) in the anionic lipid-bound NMR structure of LL-37, has not been investigated. This study reports the structure and activity of SK-24. Interestingly, SK-24 is entirely helical (~100%) in phosphate buffer (PBS), more than LL-37 (84%), GI-20 (75%), and GF-17 (33%), while RI-10 and 17BIPHE2 are essentially randomly coiled (helix%: 7–10%). These results …


January 2021, New England Osteopathic Heritage Center Jan 2021

January 2021, New England Osteopathic Heritage Center

New England Osteopathic Heritage Center Newsletter

New England Osteopathic Heritage Center's annual newsletter for January 2021