Medicine and Health Sciences Commons^™

Avian Visual Ecologists Should Consider Uv Absorbance And All Sensory Modalities: A Response To Wisenden Et Al. (2020), Sean T. O'Daniels, Scott J. Werner, Ken Yasukawa

United States Department of Agriculture Wildlife Services: Staff Publications

In a recent publication, Wisenden et al. (2020) examined responses of territorial male Red-winged Blackbirds (Agelaius phoeniceus) to models constructed with ultraviolet (UV)-reflective red epaulets for the purpose of determining if the addition of UV reflectance to epaulets ("UV+") changed the effectiveness of signals to receivers relative to "control" epaulets under field conditions. The authors hypothesized that "UV+epaulet coloration represents a visual signal with increased efficacy in territorial interactions." They presented behavioral data but no visual modeling data. Our aims in this commentary are to suggest alternative terms to those used by the authors, to express concern about the use …

The Impact Of Recipient And Donor Characteristics On Kidney Transplant Graft Survival, Ashraf Donia, Azza A. I. Elmenyawia, Tarek T. Ahmed

Journal of Medicine in Scientific Research

Introduction Many factors determine the outcomes of renal transplant, including characteristics of both donors and recipients. Antihuman leukocyte antigen donor-specific antibodies are strongly linked to antibody-mediated rejection and late allograft loss. Aim The aim was to determine the effect of recipient and donor characteristics on kidney transplant graft survival, with special stress on panel-reactive antibodies. Participants and methods This study included 168 adult recipient and donor couples. The authors analyzed data of kidney transplants performed between the years of 2008 and 2018 at National Institute of Urology and Nephrology. Results The authors found a significant increase in renal failure in …

Importance Of Pgc-1Α Gene Expression In Egyptian Hemodialysis Patients, Ashraf Donia, Azza A. I. Elmenyawi

Journal of Medicine in Scientific Research

Introduction The peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) is an upstream transcriptional regulator of mitochondrial biogenesis and function. Its function is immediate elimination of reactive oxygen species to get rid of their cellular destruction sequelae. Decreased PGC-1α count and less mitochondrial function take part in renal failure. COX6C gene encodes mitochondrial oxidative phosphorylation proteins. Reaction of excessive reactive oxygen species with linolenic acid results in malondialdehyde (MDA) as a breakdown product. It is an important marker for evaluating oxidative damage. Patients and methods A total of 58 hemodialysis (HD) patients in the National Institute of Urology and Nephrology and 20 …

Comparing The Effect Of Volume Preload Versus Ephedrine Infusion For The Prevention Of Hypotension Due To Spinal Anesthesia For Lower Abdominal And Lower Limb Vascular Surgery, Ashraf A. H. Mahmoud Soliman

Journal of Medicine in Scientific Research

Objective To evaluate the efficacy of ephedrine infusion without preblock crystalloid administration in reducing the incidence of hypotension during spinal anesthesia. Patients and methods Fifty patients presented for lower abdominal and lower limb surgery under spinal anesthesia who were divided into equal groups (group F and group E), each group had 25 patients each. Results As regards demographic data there was no statistical significance between both groups. As regards blood pressure there is statistical significance between both groups except at 4 and 22 min postspinal; regarding heart rate there was no statistical significance between both groups; and regarding the incidence …

The Use Of Ultrasound Indices To Evaluate Volume Status And Fluid Responsiveness In Patients With Septic Shock, Ashraf A. H. Mahmoud, Wael A. E. El Hakeem

Journal of Medicine in Scientific Research

Objective The purpose of this study is to assess the use of ultrasound indices to evaluate volume status and fluid responsiveness in patients with septic shock. Patients and methods A total of 40 successive patients aged above 40 years, with septic shock on admission to the ICU, were enrolled in the study, comprising 26 fluid responders and 14 fluid nonresponders. Results Regarding demographic data and other patient characteristics, no statistically significant difference between both the study groups was seen. Regard baseline hemodynamics data, there was no statistically significant difference between both groups. but after fluid bolus, there was a statistically …

Initial Experience Of Thoracoscopic Video-Assisted Minimally Invasive Mitral Valve Surgery At National Heart Institute, Ahmed M. E. Abdelgawad, Ahmed Zayed, Tamer Elbanna

Journal of Medicine in Scientific Research

Background Advancements in instruments and thoracoscopes and the evolution of cannulation techniques and cannulae types for cardiopulmonary bypass as well as cardiopulmonary bypass machines during the past decade have encouraged many surgeons to adopt minimally invasive mitral valve surgery (MIMVS). Today, MIMVS has become the standard approach for many surgeons and institutions. Patients and methods This is a nonrandomized prospective study in which 150 patients of mitral valve pathology scheduled for mitral valve surgery over a period of 3 years from March 2014 to May 2017 at National Heart Institute were allocated to two groups after fulfilling the inclusion criteria. …

Invasive Versus Noninvasive Assessment Of Functional Significance Of Intermediate Coronary Artery Lesions, Ahmed Zayed

Journal of Medicine in Scientific Research

Background Myocardial perfusion imaging (MPI) is noninvasive test used for evaluation of functional significance of borderline coronary artery lesions. Moreover, instantaneous wave-free ratio (IFR) is a well-validated invasive method used for the same purpose. Objectives To compare the results of MPI and IFR in detection of ischemia in patients with single intermediate coronary artery lesion. Patients and methods A total of 60 patients with single intermediate coronary artery stenosis, visually judged as angiographic stenosis more than or equal to 50% and less than 70% during coronary angiography, were included. After coronary angiography, all patients were subjected to MPI and IFR …

Peribulbar Injection Of Triamcinolone Acetonide As An Outpatient Clinic Procedure In The Management Of Mild To Moderate Macular Edema, Mohammed S. Ahmed

Journal of Medicine in Scientific Research

Background Diabetic retinopathy is a microvascular complication of diabetes mellitus and is the most common and most blinding ophthalmic complication. Diabetic macular edema (DME) is an essential manifestation of diabetic retinopathy that occurs across all its severity levels. Several intraocular treatment modalities for diabetic eye disease exist, including per-bulbar steroid injections. This study was conducted aiming to study the clinical effect and central macular thickness decrease following an outpatient clinic simple procedure of peribulbar injection of prepared triamcinolone acetonide (TAA) as a single procedure. Patients and methods This study was performed on 100 eligible eyes in 70 consecutive patients. The …

Intravitreal Injection Of Ranibizumab (Lucentis) Versus Pan-Retinal Photocoagulation As A Preoperative Adjuvant Before Vitrectomy In Management Of Proliferative Diabetic Retinopathy, Mohammed S. Ahmed

Journal of Medicine in Scientific Research

Background Diabetic retinopathy is a microvascular complication of diabetes mellitus, and it is the most common ophthalmic complication. Pan-retinal photocoagulation (PRP) has been the standard treatment for proliferative diabetic retinopathy (PDR) and can be used as an adjuvant before vitrectomy but has adverse effects. The use of intravitreal ranibizumab has been suggested as an alternative treatment or an alternative adjuvant before vitrectomy. Aim This study was conducted to study the effect of intravitreal injection of ranibizumab 10 mg/ml (Lucentis) versus PRP as an adjuvant before vitrectomy in the management of PDR. Patients and methods This study was performed on 40 …

Relaxing Retinotomies And Retinectomies In Case Of Proliferative Diabetic Vitreoretinopathies And Tractional Retinal Detachment, Alaa Atteya, Hussam E. O. Elrashidy, Maged Adly

Journal of Medicine in Scientific Research

Introduction Radical anterior vitreous base dissection and lensectomy in combination with inferior 180° retinectomy will improve the anatomic success of complex proliferative diabetic vitreoretinopathies (PVR)-related retinal detachment. Our study aims to describe the anatomical and functional results of pars plana vitrectomy with retinotomies and relaxing retinectomies in patients with tractional retinal detachment in advanced PVR. Patients and methods A case series study was conducted on 28 eyes of patients with tractional retinal detachment with severe PVR. Preoperative and postoperative complications and final visual outcomes were recorded. The follow-up period was 12 months. Results Full reattachment rate was reached intraoperatively in …

Effect Of Repeated Peribulbar Triamcinolone Injection On Corneal Topography In Patients With Thyroid Eye Disease, Hussam E. O. Elrashidy, Laila A. Abulnasr, Nehal O. Elfarouk

Journal of Medicine in Scientific Research

Introduction Studies have shown that repeated peribulbar triamcinolone injections reduce the inflammatory signs of moderate to severe thyroid eye disease (TED). Other studies found that TED was associated with greater with-the-rule corneal astigmatism owing to fibrosis of the soft tissue in the superolateral orbital region. This study aimed to detect the effect of repeated peribulbar triamcinolone injections in patients with moderate to severe TED on corneal topography and astigmatism. Patients and methods A prospective, controlled, and randomized study was conducted that included 30 eyes with moderate to severe TED who underwent repeated peribulbar triamcinolone injections in addition to pretreatment and …

Evaluation Of Posterior Decompressive Lumbar Surgery For Multilevel Lumbar Spinal Canal Stenosis With And Without Fusion, Sameh M. Saleh

Journal of Medicine in Scientific Research

Background There is no consensus regarding the best treatment of patients with multilevel lumbar stenosis. Surgical and invasive procedures are widely used in adults with degenerative lumbar spinal stenosis when conservative treatments fail. However, little is known about the comparative efficacy and safety of these interventions. Aim and objective The aim was to study and evaluate the outcome of surgery for degenerative lumbar canal stenosis (LCS) on a clinical, radiological, and functional basis and to identify whether spinal decompression with fusion has a better effect than decompression alone for patients with degenerative lumbar spinal stenosis or not. Patients and methods …

Tibial Angioplasty In Diabetics, Ihab N. A. Hanna

Journal of Medicine in Scientific Research

Background Diabetics are pron e to develop serious complications such as nephropathy, retinal detachment, and others, and among such complications lies the devastating serious complication of diabetic foot, whether ulceration or diabetic foot infections up till gangrene. This could be attributed to either one or all of the following etiological factors: peripheral vascular disease, peripheral neuropathy, and/or infection owing to impaired immunity. Patients and methods We enrolled 88 diabetic ischemic patients with tibial artery disease confirmed by Duplex. Their mean age was 67 years (54 males and 34 females). Patients were subjected to ipsilateral antegrade transluminal or subintimal tibial angioplasty. …

Great Saphenous Vein Diameter At Different Regions And Its Relation To Reflux, Kareem Hady, Said I. El Mallah, Yahia M. Al-Khateep

Journal of Medicine in Scientific Research

Background Great saphenous vein (GSV) incompetence is involved in most cases of varicose disease. Standard preinterventional assessment is required to decide the treatment modalities. GSV diameter was measured at saphenofemoral junction, proximal thigh, distal thigh, knee, proximal leg, and distal leg. Analysis was done to find at which diameter size the reflux is expected to occur. Patient and methods The study involved 100 limbs from outpatient vascular clinic. GSV diameter was measured at the saphenofemoral junction, the proximal thigh, the distal thigh, below the knee, and mid-leg and correlated with reflux. Results Reflux in the sapheno-femoral junction (SFJ) (group I) …

Predictors Of Mortality In The Neonatal Intensive Care Unit Of El-Galaa Teaching Hospital, Michael W. G. Hany

Journal of Medicine in Scientific Research

Aim Neonatal mortality accounts for most infant mortality. Various factors influence the risk of neonatal mortality. Available estimates of survival and mortality in neonatal intensive care units (NICUs) are needed to provide antenatal counseling and guide management decisions. This study aimed to determine the predictors of admitted neonatal mortality. Patients and methods A retrospective study was done between June 2016 and May 2018 in the NICU of El-Galaa Teaching Hospital to determine the predictors of admitted neonatal mortality. Data were collected as follows: premature rupture of membranes, mode of delivery, multiple or single pregnancy, sex, weight, gestational age (GA), Apgar …

Covid-19 Pandemic And Breast Cancer Management: A Retrospective Observational Clinical Study From Pakistan, Lubna Mushtaque Vohra, Dua Jabeen, Narmeen Asif, Abdul Ahad

Section of General Surgery

Background: COVID-19 outbreak has adversely affected care of breast cancer patients world-wide. There is paucity of available data on cancer management in lower-middle income countries during this pandemic, we sought to determine the institutional approach towards management of breast cancer patients and the outcomes during COVID-19 pandemic at our institution.
Materials and methods: Clinicopathological and treatment record of cancer patients who presented to the Breast Clinic from 15th March to 31^st December 2020 was retrieved from the institutional database for this retrospective clinical observational study.
Results: A total of 292 patients were qualified for the analysis in which 206 …

Association Of Vitamin D Deficiency And Disease Activity In Systemic Lupus Erythematosus Patients: Two-Year Follow-Up Study, Ainan Arshad, Saad Bin Zafar Mahmood, Ahmed Ayaz, Adil A. Manji, Akash Kumar Ahuja

Section of Internal Medicine

Objectives: This study aims to determine the prevalence of vitamin D deficiency in Pakistani systemic lupus erythematosus (SLE) patients and the effect of vitamin D deficiency on the severity and outcomes of SLE.
Patients and methods: This retrospective study evaluated SLE patients presenting to our hospital between January 2009 and December 2018. A total of 98 patients (13 males, 85 females; mean age 39.8±14.9 years; range, 16 to 73 years) with vitamin D levels available at the time of diagnosis were included in the study. Disease activity was measured using SLE disease activity score at the time of diagnosis and …

Knowledge And Attitude Towards Identification And Management Of Sepsis Among Resident Physicians In A Tertiary Care Teaching Hospital In Pakistan, Ainan Arshad, Abdul Aziz, Ahmed Ayaz, Syed Maaz Salahuddin, Bushra Jamil

Section of Internal Medicine

This study was conducted to determine the compliance and knowledge of sepsis guidelines among resident physicians in a tertiary care hospital of a developing country. A self-structured validated questionnaire was prepared to evaluate compliance and knowledge of the Surviving Sepsis Campaign (SSC) guidelines. A total of 76 resident physicians completed the questionnaire; out of these, 51 (67%) were from Internal Medicine department and 25 (33%) were from Emergency Medicine department of the Aga Khan University Hospital, Karachi. A total of 71 (93%) participants claimed to be aware of the SSC guidelines but only 20 (26%) considered themselves very knowledgeable on …

An In Vitro Study Of Hydrangea Arborescens, Homoeopathic Preparation As An Inhibitor Of Calcium Oxalate Crystallisation, Rupali Telang

Indian Journal of Research in Homoeopathy

Background: Homoeopathic mother tincture Hydrangea arborescens (Hydrang.) is conventionally used for urinary complaints, such as urinary tract infection, renal stones and prostate hypertrophy. However, the mode of its action for annihilation of complaints remains uncertain. This study was designed to investigate in vitro effect of homoeopathic preparations of Hydrang. on urolithiasis (Calcium oxalate [CaOx] crystallisation). Objective: To analyse the role of Hydrang. a, homoeopathic preparation in an in-vitro CAOx crystallisation. Materials and Methods: Spectrophotometric crystallisation assay was carried on and the slopes of nucleation and aggregation phases were calculated using linear regression analysis, and the percentage inhibition exerted by the …

Preclinical Updates Of The Homoeopathic Medicines Used In Diabetes Mellitus: A Narrative Review, G Kumar, V Chitra, Pankaj Gupta, Bibaswan Biswas, Arya Renu

Indian Journal of Research in Homoeopathy

Introduction: Homoeopathy, one of the most commonly employed alternative medicines globally, has a wide range of role in the management of diabetes. Screening of the action of homoeopathic medicines in diabetes on animal model not only helps in validating their antidiabetic potential but also aids in understanding their effect on living systems and their mechanism of action. The present review focusses on the collection of results of pre-clinical studies carried out on homoeopathic medicines employed in the management of diabetes. Methodology: PubMed, HomBRex portal, and published literature such as library catalogue were searched up to November 2019. The search terms …

Obliteration Of Ranula With Homoeopathic Treatment: A Case Report, Partha Pal

Indian Journal of Research in Homoeopathy

Introduction: Ranula is a soft translucent swelling that occurs in the floor of the mouth usually causing mild discomfort to the patient. Conventional therapeutic modalities range from the injection of sclerosing agents to various surgical techniques. Only a few documented cases with non-surgical management are available on literature search, as surgery is considered to be the mainstay for this clinical condition. Case Summary: This is a case of a female child with a painless, cystic swelling in the right side of the floor of the mouth of 3-month duration and another smaller painless cystic swelling on the inner side of …

Active Principle In Potentised Medicines: Nanoparticle Versus Quantum Domain – An Overview, Papiya Nandy, Durga Bhar

Indian Journal of Research in Homoeopathy

Background: The fact that homoeopathic medicines act even at very high dilutions has created a confusion amongst scientists. This led to different models such as formation of nanoparticles and memory of water. The basic question 'what is responsible for physiological activity of homoeopathic medicines' is yet to be answered conclusively. Objective: The objective of this overview was to find out if formation of nanoparticles or creation of quantum domain in the medium is responsible for the physiological activity of homoeopathic medicines. Methods: This overview is based on the experiments done between 2004 and 2019. Results: The succussion of the medicine …

Research Highlights, Sarita Gola, Parul Parul

Indian Journal of Research in Homoeopathy

No abstract provided.

Control Of Linear Head And Trunk Acceleration During Gait After Unilateral Vestibular Deficits, Brian J. Loyd, Jane Saviers-Steiger, Annie Fangman, Serene S. Paul, Peter C. Fino, Mark E. Lester, Leland E. Dibble

Physical Therapy Faculty Publications

Objective

To use clinically available inertial measurement units to quantify the control of linear accelerations at the head and trunk during gait in different sensory conditions in individuals with unilateral vestibular loss.

Design

Observational study.

Setting

Outpatient research laboratory.

Participants

Individuals (n=13; mean age, 47.6±13.7y; 69% women) 6 weeks after vestibular schwannomaresection surgery and vestibular healthy participants (n=16; mean age, 29.7±5.9y; 56% women).

Intervention

Not applicable.

Main Outcome Measures

Walking speed normalized, root mean square values of cranial-caudal, medial-lateral, and anterior-posterior directed linear accelerations at the head and the trunk while walking in 2 visual sensory conditions (eyes open …

Relationships Between Disaccharidase Deficiencies, Duodenal Inflammation And Symptom Profile In Children With Abdominal Pain., Jennifer Colombo, Chance S. Friesen, Uttam Garg, Craig A. Friesen, William San Pablo

Manuscripts, Articles, Book Chapters and Other Papers

Abdominal pain has been associated with disaccharidase deficiencies. While relationships with individual symptoms have been assessed, relationships between disaccharidase deficiencies and symptom complexes or inflammation have not been evaluated in this group. The primary aims of the current study were to assess relationships between disaccharidase deficiency and symptoms or symptom complexes and duodenal inflammation, respectively. Patients with abdominal pain who underwent endoscopy with evaluation of disaccharidase activity levels were identified. After excluding all patients with inflammatory bowel disease, celiac disease, H. pylori, or gross endoscopic lesions, patients were evaluated for disaccharidase deficiency frequency. Disaccharidase were compared between patients with and …

Continuous Chain Of Exporting Wuhan Novel Coronavirus Infection: A Comparison Of Primary And Secondary Step Rates, Rujittika Mungmungpuntipantip, Viroj Wiwanitkit

Journal of Medicine in Scientific Research

No abstract provided.

Redo-Mitral Valve Replacement And Predictors Of Operative Mortality: A Single-Institute Experience, Ahmed M. E. Abdelgawad, Ahmed Abdelaziz

Journal of Medicine in Scientific Research

Background In spite of improved survival of first-time mitral valve replacement (MVR), operative mortality associated with redo-mitral valve surgery is still higher than that of the primary operation. Consequently, more patients require redo-MVR, and studies investigating the operative outcome with current techniques and prostheses are thus needed. Patients and methods This is a nonrandomized prospective study that included 83 patients who underwent redo-MVR with either bioprosthetic or mechanical valves between March 2014 and December 2017 at National Heart Institute. Recorded data were analyzed using the statistical package for social sciences, version 23.0 (IBM SPSS). All preoperative and operative data were …

Detection Of Mutations Associated With Variants Of Concern Via High Throughput 2 Sequencing Of Sars-Cov-2 Isolated From Nyc Wastewater, Davida S. Smyth, Monica Trujillo, Kristen Cheung, Anna Gao, Irene Hoxie, Sherin Kannoly, Nanami Kubota, Michelle Markman, Kaung Myat San, Geena Sompanya, John J. Dennehy

Publications and Research

Monitoring SARS-CoV-2 genetic diversity is strongly indicated because diversifying selection may lead to the emergence of novel variants resistant to naturally acquired or vaccine-induced immunity. To date, most data on SARS-CoV-2 genetic diversity has come from the sequencing of clinical samples, but such studies may suffer limitations due to costs and throughput. Wastewater-based epidemiology may provide an alternative and complementary approach for monitoring communities for novel variants. Given that SARS-CoV-2 can infect the cells of the human gut and is found in high concentrations in feces, wastewater may be a valuable source of SARS-CoV-2 RNA, which can be deep sequenced …

Development Of A Mobile Application To Promote Family Caregiver Engagement In Symptom Assessment And Management During Mechanical Ventilation In The Intensive Care Unit, Christina Bach, Erin Grotts, Jennifer Heusinkvelt, Bunny J. Pozehl, Ellie Rubenfeld, Abigail Wawers, Breanna D. Hetland

Posters and Presentations: College of Nursing

No abstract provided.

Osteogenic Differentiation Of Adipose-Derived Mesenchymal Stem Cells Using 3d-Printed Pdlla/ Β-Tcp Nanocomposite Scaffolds, Ashkan Bigham, Amir Hamed Aghajanian, Mehdi Movahedi, Mansoureh Sattary, Mohammad Rafienia, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Designing bone scaffolds containing both organic and inorganic composites simulating the architecture of the bone is the most important principle in bone tissue engineering. The objective of this study was to fabricate a composite scaffold containing poly (D, l)-lactide (PDLLA) and β-tricalcium phosphate (β-TCP) as a platform for osteogenic differentiation of adipose-derived mesenchymal stem cells. In this study, PDLLA/β-TCP scaffolds were fabricated using three-dimensional printing (3D) technology through melt excursion technique. The physicomechanical characteristics, including microstructure, mechanical properties, of the customized scaffolds were investigated. Further, the in vitro biological characteristics of manufactured scaffolds were evaluated in conjugation with buccal fat …