Medicine and Health Sciences Commons^™

The Prison Litigation Reform Act And The Physical Injury Requirement In The Context Of Transgender Inmates, Hunter Kravitz

Cardozo International & Comparative Law Review

The note examines the impact of the Prison Litigation Reform Act (PLRA) on transgender inmates, focusing on its physical injury requirement, which disproportionately bars access to justice for those with mental or emotional injuries. It highlights the ethical and constitutional concerns arising from the PLRA's application, particularly its unequal treatment of transgender inmates, and advocates for reforms to ensure equitable access to justice.

The Last Frontier For Global Non-Communicable Disease Action: The Emergency Department—A Cross-Sectional Study From East Africa, Christine Ngaruiya, Mbatha Wambua, Thomas Kedera Mutua, Daniel Owambo, Morgan Muchemi, Kipkoech Rop, Kaitlin R. Maciejewski, Rebecca Leff, Mugane Mutua, Benjamin Wachira

Emergency Medicine, East Africa

Introduction: Deaths due to non-communicable diseases (NCDs) have surpassed those due to communicable diseases globally and are projected to do so in Africa by 2030. Despite demonstrated effectiveness in high-income country (HIC) settings, the ED is a primary source of NCD care that has been under-prioritized in Africa. In this study, we assess the burden of leading NCDs and NCD risk factors in Kenyan Casualty Department patients to inform interventions targeting patients with NCDs in emergency care settings.

Materials and methods: Using the WHO STEPwise approach to surveillance (STEPS) tool and the Personal Health Questionnaire (PHQ-9), we conducted a …

Meal-Induced Symptoms In Children With Dyspepsia-Relationships To Sex And The Presence Of Gastroparesis, Liz Febo-Rodriguez, Bruno P Chumpitazi, Salma Musaad, Andrew C Sher, Robert J Shulman

Children’s Nutrition Research Center Staff Publications

Objectives: To test the hypothesis that in children with dyspepsia, prospective symptom severity following ingestion of a meal would correlate with percent gastric retention, and those ultimately diagnosed with gastroparesis would report worse symptoms.

Study design: Prospective, single-center study with 104 children with dyspepsia completing a prospective dyspepsia symptom questionnaire before and after eating a standardized Tougas meal during gastric emptying scintigraphy. Main outcomes included correlation between gastric retention and symptoms and comparison of symptom severity between those with and without gastroparesis.

Results: Fifty-two children (50%) had gastroparesis (gastroparesis: 12.5 ± 2.9 years, 65% female; nongastroparesis: 13.0 ± 2.9 years, …

Evidence Based Programs (Ebp) Rate Increase Cost Projection Model, Evidence To Practice, Cep Briefs, Ronnie Rubin, Kaylin Beiter, Stephen Phillippi

Policy & Position Papers

No abstract provided.

Financial & Policy Challenges To Evidence Based Practice (Ebp) Implementation, Evidence To Practice, Cep Briefs, Ronnie Rubin, Willandra Whiting, Stephen Phillippi

Policy & Position Papers

No abstract provided.

Provider Survey Of Use Of Ebp Billing Codes Vs. Utilization, Evidence To Practice, Cep Briefs, Kaylin Beiter, Stephen Phillippi, Bumbarger

Policy & Position Papers

No abstract provided.

Association Of Race With Lung Cancer Risk Among Adults Undergoing Lung Cancer Screening., Christine S Shusted, Nathaniel R Evans, Hee-Soon Juon, Gregory C Kane, Julie A Barta

Division of Pulmonary, Allergy, and Critical Care Medicine Faculty Papers

No abstract provided.

The Covid-19 Impact On Health Administration Education: Understanding Student Perspectives On The Transition From In-Person To Remote Course Instruction, C. J. Louis, A. Landry, G. Silvera, J. Robbins, Patrick D. Shay, H. Lee, J. Felix, S. Cave, P. Fishman

Health Care Administration Faculty Research

COVID-19 has infected millions of Americans. To combat the spread of the virus, state and local officials instituted social distancing guidelines that forced schools to shutter campuses and transition from in-person to remote learning. In this study, we examined health administration (HA) student perspectives on the transition from in-person to remote learning. We sought to understand how schools attempted to manage student concerns, how adaptations to remote learning were implemented, and what influences the transition had on student stress and anxiety. We used a mixed-methods study design that included (1) a survey of undergraduate and graduate students from six geographically …

Clerkship Student Perceived Educational Effectiveness Of Virtual Simulation, Claire L. Paulson Do, Jamie Allen Do, Jessica Davis Do, Julie A. Fritzges Do, Deepak A. Jayant Do, Michael C. Nguyen Md, Colleen Urban Do, Charles C. Worrilow Md, Dawn M. Yenser C-Tagme, Bryan G. Kane Md

Department of Emergency Medicine

No abstract provided.

The Bulletin: Sidney Kimmel Medical College At Thomas Jefferson University, Volume 70, Issue 1, Spring 2021

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

This issue includes:

• Dean’s Column Leveling the Field, Paving the Way to Success
• Time Capsule Milestones and Influencers: Women in Medicine at Jefferson
• On Campus
• A Message from Elizabeth A. Dale Building a New Legend
• Discovery Predicting Heart Disease from the Skin
• Gender Equality in Medicine Still a Work in Progress
• Faculty Profile Diane Merry
• Student Profile Matt Rohn and Mark Shapses
• Class Notes 2020 Virtual Alumni Weekend
• Love Story Physician-Researchers Found Life’s Work—and Each Other—at Jefferson
• Class Agent
• In Memoriam
• Bookshelf

Demand Satisfied By Modern Contraceptive Among Married Women Of Reproductive Age In Kenya, Peter Gichangi, Michael Waithaka, Mary Thiongo, Alfred Agwanda, Scott Radloff, Amy Tsui, Linea Zimmerman, Marleen Temmerman

Obstetrics and Gynaecology, East Africa

Background: Demand for family planning met/satisfied with modern contraceptive methods (mDFPS) has been proposed to track progress in Family Planning (FP) programs for Sustainable Development Goals. This study measured mDFPS among married women of reproductive age (MWRA) in Kenya to identify which groups were not being reached by FP programs.

Materials and methods: Performance, Monitoring and Accountability 2020 (PMA2020) survey data from 2014–2018 was used. PMA2020 surveys are cross-sectional including women 15–49 years. PMA2020 used a 2-stage cluster design with urban/rural regions as strata with random selection of households. Univariate and multivariate analysis was done using stata V15.

Results: Of …

Prenatal Maternal Mood Entropy Is Associated With Child Neurodevelopment, Mariann A. Howland, Curt A. Sandman, Elysia Poggi Davis, Hal S. Stern, Michael Phelan, Tallie Z. Baram, Laura M. Glynn

Psychology Faculty Articles and Research

Emerging evidence indicates that the predictability of signals early in life may influence the developing brain. This study examines links between a novel indicator of maternal mood dysregulation, mood entropy, and child neurodevelopmental outcomes. Associations between prenatal maternal mood entropy and child neurodevelopment were assessed in 2 longitudinal cohorts. Maternal mood was measured several times over pregnancy beginning as early as 15 weeks’ gestation. Shannon’s mood entropy was applied to distributions of mothers’ responses on mood questionnaires. Child cognitive and language development were evaluated at 2 and 6–9 years of age. Higher prenatal maternal mood entropy was associated with lower …

Cell Signaling Regulation In Salivary Gland Development, Akiko Suzuki, Kenichi Ogata, Junichi Iwata

Faculty, Staff and Student Publications

The mammalian salivary gland develops as a highly branched structure designed to produce and secrete saliva. This review focuses on research conducted on mammalian salivary gland development, particularly on the differentiation of acinar, ductal, and myoepithelial cells. We discuss recent studies that provide conceptual advances in the understanding of the molecular mechanisms of salivary gland development. In addition, we describe the organogenesis of submandibular glands (SMGs), model systems used for the study of SMG development, and the key signaling pathways as well as cellular processes involved in salivary gland development. The findings from the recent studies elucidating the identity of …

Effects Of Caffeine Consumption On Cognitive Performance In Anatomy And Physiology Students, Sydney Wingfield

Honors Theses

Caffeine has often been associated with college students and their study habits; however, little research has been done to explore if it is actually beneficial to the students’ cognitive performance and academic success. While current studies have explored various aspects of caffeine’s influence on specific areas of cognition relevant to their own studies, there is a lack of research on how it influences academic settings. Within the present study, it is believed that caffeine usage will not cause a significant improvement in individual academic performance despite of the known physiological and cognitive effects on the students. The study consisted of …

Performance And Determinants Of Serum Creatinine And Cystatin C-Based Gfr Estimating Equations In South Asians, Yeli Wang, Andrew S. Levey, Lesley A. Inker, Saleem Jessani, Rasool Bux, Zainab Samad, Ali Raza Khan, Amy B. Karger, John C. Allen, Tazeen H. Jafar

Community Health Sciences

Introduction: The creatinine-based Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) estimated glomerular filtration rate (eGFR) equation was calibrated for the general Pakistan population (eGFRcr-PK) to eliminate bias and improve accuracy. Cystatin C-based CKD-EPI equations (eGFRcys and eGFRcr-cys) have not been assessed in this population, and non-GFR determinants of cystatin C are unknown.
Methods: We assessed eGFRcys, eGFRcr-cys, and non-GFR determinants of cystatin C in a cross-sectional study of 557 participants (≥40 years of age) from Pakistan. We compared bias (median difference in measured GFR [mGFR] and eGFR), precision (interquartile range [IQR] of differences), accuracy (percentage of eGFR within 30% of mGFR), …

Characterization Of Age-Associated Gut Microbial Dysbiosis And Plasma Metabolite Alterations In People Living With Hiv (Plwh)., R. Sighal, Smita Ghare, Vaughn Bryant, Sabina Gautam, Chanakya Charan Tirumala, Andrea Reyes-Vega, Craig J. Mcclain, Ronald Cohen, Varand Govind, R L. Cook, Shirish Barve

Faculty and Staff Scholarship

Background: HIV-1 infection and aging are independently associated with gut microbial dysbiosis and neurocognitive impairment. However, the interactive effects of HIV-infection and aging on the development of specific pathogenic features of gut microbial dysbiosis and consequent metabolic abnormalities associated with neurocognitive dysfunction remain largely undetermined and were examined in the present study

Improving Nurses’ Provision Of Neuroprotective Care In The Nicu: A Quality Improvement Project, Tammi Reeves-Messner

Doctoral Projects

Infants born prematurely (less than 37 weeks’ gestation) require specialized medical and nursing care to survive. Most of these babies require some form of respiratory, cardiovascular, thermal, and nutritional support as their bodies are not yet physiologically mature enough to handle these basic functions on their own. These supports include basic care such as diaper changes and feeding as well as life-saving interventions which include ventilation, intravenous nutrition, thermal regulation, and vasoactive medications. Depending on their gestational age or their diagnoses, they may require higher levels of support, such as nitric oxide gas delivered via a ventilator (Lai et al, …

Escape This Emergency Room: Simulation Education During A Pandemic, Michael C. Nguyen Md, Nicole Elliott Do, Julie A. Fritzges Do, Louis Morolla Do, Steven A Johnson Md

Department of Emergency Medicine

No abstract provided.

Interventions To Reduce Emergency Department Demand During A Pandemic, Cynthia Wang Bs, Bryan G. Kane Md, Jason L. Forgeon Md, Justin Giordano Do, Armando Orta Md, Richard S. Mackenzie Md

Department of Emergency Medicine

No abstract provided.

Level I Nodal Positivity As A Factor For Involvement Of The Submandibular Gland In Oral Cavity Carcinoma: A Case Series Report, Hamdan Ahmed Pasha, Rahim Dhanani, Shayan Khalid, Kulsoom Ghias, Mumtaz Jamshed Khan

Section of Otolaryngology, Head & Neck Surgery

Introduction: The routine practice of neck dissection in the surgical management of oral carcinoma has evolved into a more functionally conservative approach. Over time, the rationale for removal of the submandibular gland has been questioned. Routine extirpation of the submandibular gland can aggravate the xerostomia experienced by many patients, significantly affecting their quality of life.
Objective: The objective of the present study was to determine the incidence of submandibular gland metastases in oral cavity carcinoma and to identify possible factors that may affect their involvement.
Methods: A total of 149 cases of oral carcinoma presenting at a private tertiary care …

Intimate Partner Violence Is A Barrier To Antiretroviral Therapy Adherence Among Hiv - Positive Women: Evidence From Government Facilities In Kenya, Bornice C. Biomndo, Alexander Bergmann, Nils Lahmann, Lukoye Atwoli

Internal Medicine, East Africa

Introduction: Intimate Partner Violence (IPV) is linked to low engagement with HIV management services and adverse clinical outcomes, including poor ART adherence. In sub-Saharan Africa, studies on pregnant/postpartum women and transactional sex workers have produced divergent evidence regarding IPV’s association with poor ART adherence. We investigate this association among a broad group of women.

Methods: We sampled 408 HIV-positive women receiving free ART from different types of HIV clinics at government health facilities, assessing for IPV exposure by a current partner, ART adherence rate, and other factors that affect ART adherence (e.g. education, disclosure). ART adherence rates were measured using …

Targeting Resistance To Radiation-Immunotherapy In Cold Hnsccs By Modulating The Treg-Dendritic Cell Axis., Michael W. Knitz, Thomas E. Bickett, Laurel B. Darragh, Ayman J. Oweida, Shilpa Bhatia, Benjamin Van Court, Shiv Bhuvane, Miles Piper, Jacob Gadwa, Adam C. Mueller, Diemmy Nguyen, Varuna Nangia, Douglas G. Osborne, Xiyuan Bai, Sarah E. Ferrara, Mary-Keara Boss, Andrew Goodspeed, Matthew A. Burchill, Beth A. Jirón Tamburini, Edward D. Chan, Curtis R. Pickering, Eric T. Clambey, Sana D. Karam

Department of Radiation Oncology Faculty Papers

BACKGROUND: Numerous trials combining radiation therapy (RT) and immunotherapy in head and neck squamous cell carcinoma (HNSCC) are failing. Using preclinical immune cold models of HNSCC resistant to RT-immune checkpoint inhibitors, we investigate therapeutic approaches of overcoming such resistance by examining the differential microenvironmental response to RT.

METHODS: We subjected two HPV-negative orthotopic mouse models of HNSCC to combination RT, regulatory T cells (Treg) depletion, and/or CD137 agonism. Tumor growth was measured and intratumorous and lymph node immune populations were compared among treatment groups. Human gene sets, genetically engineered mouse models DEREG and BATF3-/-, flow and time-of-flight cytometry, RNA-Seq, …

Quality Outcomes For Pediatric Colorectal Surgery Treated During Short-Term International Medical Service Trips At A Dedicated Site In Honduras., Wilfried Krois, Rebecca M. Rentea, Pastora X. Hernandez, Juan Craniotis-Rios, Richard J. Wood, Marc A. Levitt, Carlos A. Reck-Burneo

Manuscripts, Articles, Book Chapters and Other Papers

INTRODUCTION: Short-term international medical service trips (MSTs) provide specialized care in resource-constrained countries. There are limited data on immediate and long-term reported outcomes following specialty MST. We hypothesized that dedicated collaborative MST team and host institution produce outcomes and results comparable to those of high-income settings. Our primary aim was to analyze the long-term surgical and functional outcomes of our specialty-specific MSTs following five years of annual MST in Honduras.

METHODS: We performed a single-institution retrospective analysis of 56 children who underwent colorectal and pelvic reconstructive operations between 2014 and 2018. Demographics, diagnosis, comorbidities, type of repair, long-term complications, and …

Cerebral Perfusion Using The Resistive Index On Doppler Ultrasound In Extremely Premature Newborns With Ventriculomegaly, Rawad Obeid, Marni Jacobs, Taeun Chang, An N. Massaro, Dorothy Bulas, Anna Penn

Conference Presentation Abstracts

Background: In extremely premature newborns, the effect of ventriculomegaly, as seen on cranial ultrasound (CUS), on cerebral perfusion is not well studied. The resistive index (RI) (Figure-1) is a marker of change of the flow velocity on Doppler ultrasound that could be used to understand this effect.

Objective: To identify the following: 1- The normal RI values in premature infants without intraventricular hemorrhage (IVH), 2- The relation between the RI in the major intracerebral arteries and the ventricular size on CUS using the fronto-temporal horn ratio (FTHR) in newborns with and without IVH, and 3-The association with white matter injury …

The Emergence Of Artificial Intelligence In Dental Care Delivery, Robert A. Faiella D.M.D., M.M.Sc., M.B.A., Shaju Puthussery M.S.

The Journal of the Michigan Dental Association

This comprehensive review explores the transformative role of Artificial Intelligence (AI) in the evolution of dental care delivery. As oral health specialists, dentists continually seek to enhance their ability to prevent, diagnose, and manage oral diseases while maintaining and improving patient oral health. The integration of AI offers unprecedented opportunities to revolutionize dental practice and patient care.

AI is rapidly advancing in healthcare, including dental care, with a projected global healthcare AI market value of $45.2 billion by 2026. This technology can potentially revolutionize prevention, diagnosis, treatment planning, and treatment outcomes.

Aspects of AI in dentistry include:

· Diagnostic Accuracy …

Ai Use In Claims Processing And Utilization Review, Robert Rosenthal Dds

The Journal of the Michigan Dental Association

This paper investigates the use of artificial intelligence (AI) in claims processing and utilization review in the dental industry. This article aims to explore the potential benefits of AI in this area, such as increased efficiency, accuracy, and fraud detection. The paper begins by providing an overview of the current state of claims processing and utilization review in the dental industry. It then discusses the potential applications of AI in this area, such as automated claims adjudication, predictive analytics, and image recognition. The paper then presents a case study of P&R Dental Strategies, LLC, a leading business intelligence solutions provider …

Growing South Dakota (Spring 2021), College Of Agriculture, Food And Environmental Sciences

Growing South Dakota (Publication of the College of Agriculture, Food and Environmental Sciences)

This issue contains the 2020 SDSU Extension Annual Report and 2020 South Dakota Agricultural Experiment Station Annual Report.

[Page] 3 COVID-19 Impacts
[Page] 9 Precision Agriculture: What's New
[Page] 13 Featured Research
[Page] 19 SDSU Extension 2020 Annual Report
[Page] 45 South Dakota Agricultural Experiment Station 2020 Annual Report
[Page] 55 CAFES News and Updates
[Page] 67 Alumni News
[Page] 75 Alumni Gone Down in History
[Page] 81 Jackrabbits Now and Then: A Current Student and Alumni Q&A

Powered By Ai, Christopher J. Smiley

The Journal of the Michigan Dental Association

Artificial Intelligence (AI) is revolutionizing dental practice through its ability to process vast amounts of data, enhance diagnosis, and improve patient care. However, AI introduces the challenge of bias and ethical considerations. Dentists and dental benefit providers are utilizing AI for early disease detection and efficient data management, but transparency and fairness in AI algorithms are vital. The Rome Call for AI Ethics emphasizes ethical, non-biased AI development. In the broader context, AI-driven marketing and predictive behavior raise concerns about privacy and ethical data use. The dental community must embrace AI's power while upholding ethical standards and transparency.

Early Premature Infant Physiologic And Behavioral Indicators Of Ans Instability, Karen Popp Becker

Theses and Dissertations

The advanced survival of the early premature infant (EPI) since the post-surfactant era has not improved many comorbidities. EPI comorbidities influence their lifelong health, social, and cognitive outcomes. EPIs often have immature and disorganized responses to stimuli during the neonatal period. EPIs respond to stressors from the Neonatal Intensive Care Unit’s (NICU) environment, stimulation, or disease states based on physiologic system changes, often resulting in observable behavioral changes. Both physiologic and behavioral changes reflect autonomic nervous system (ANS) disruption, thus instability. Instability of the ANS due to chronic stressors, can lead to chronic physiologic dysregulation and lead to lifelong health …

Panaxynol’S Pharmacokinetic Properties And Its Mechanism Of Action In Treating Ulcerative Colitis, Hossam Sami Tashkandi

Theses and Dissertations

Panaxynol (PA) is a polyacetylene that was found to be an abundant active ingredient in American ginseng (AG). Pharmacokinetics (PK) studies of PA were conducted to determine how the body reacts to it by using liquid chromatography-tandem mass spectrometry (LC-MS/MS) to measure PA’s concentration. In vitro, PA’s clearance by microsome metabolism is a moderate 48.1 minutes. In vivo, CD-1® mice were treated with PA by intravenous (IV) injection or orally (PO). Concentrations of PA were measured in plasma and tissue using LC-MS/MS. Also, PA has a high bioavailability of 50.4% and a moderate half-life of 5.9 hours. In addition, mice …