Medicine and Health Sciences Commons^™

2021-04-23_Michiganoverview_Covidvaccinestats, Michigan Department Of Health & Human Services

Michigan COVID-19 Vaccine Data

The COVID Vaccine Dashboard page was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus/0,9753,7-406-98178_103214-547150--,00.html.

Data is updated Monday through Saturday. Previously reported numbers of administered vaccine doses may change as new data are received. A possible lag in reporting vaccine doses will result in increases in numbers previously reported.

This report is created by the Michigan Department of Health and Human Services Division of Immunization from data reported to the Michigan Care Improvement Registry (MCIR).

The dashboard contained the tabs Vaccines Delivered, Delivery Trend, Doses Administered, Doses by Vaccine, Doses Metrics, Coverage, Coverage Metrics …

Brain Health Research Collaborative, Susan C. Davies

Thomas C. Hunt Building a Research Community Day

This session involves discussion of a proposed Brain Health Collaboratory to provide research, education/outreach, and clinical opportunities for faculty and students at the University of Dayton and the Greater Dayton community. This collaboration aligns with core components of UD’s Vision, including developing partnerships that contribute to the greater good and enhancing interdisciplinary research. This initiative will also provide a strong opportunity for collaboration among SEHS education and health sciences programs and with other departments/ programs across campus.

Streamlining Care For Children With Autism Spectrum Disorder, Siavash Rostami Jafarabad

DNP Qualifying Manuscripts

Background: Autism spectrum disorder (ASD) is a chronic and developmental disorder that affects about one out of every 65 children in California, and one in 59 children in the United States. Children with ASD have difficulty communicating and interacting with others, and experience oversensitivity to new stimuli and environments.

Problem: In healthcare settings, children with ASD experience numerous challenges related to lack of adequate knowledge and education of staff regarding ASD, and lack of appropriate environmental and sensory resources which reduce quality of care provided to this population.

Objective: To analyze and evaluate the evidence regarding effective staff education and …

2021-04-23_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

Evaluation Of An Elopement Risk Assessment Tool In An Acute Inpatient Psychiatric Hospital, Beth Lockhart

Dissertations

Persons admitted to acute care, inpatient psychiatric facilities often pose a threat to themselves or others, a situation which could quickly devolve if they were to leave treatment prematurely. There is a need for an elopement risk assessment with appropriate interventions correlating to level of risk. An acute care, inpatient psychiatric hospital implemented an elopement risk assessment tool in March of 2020. This quality improvement project used an observational descriptive design and comprised of a retrospective chart review, aimed to determine the effectiveness of the risk assessment tool on decreasing elopements. Charts of those that eloped in 2019 (n=8) and …

Synthesis And Characterization Of Antiviral Drug Candidate Molecules Against The Respiratory Syncytial Virus, Ali Abbas Sabi

Dissertations

Abstract

Pyrrole-imidazole polyamides (PAs) are small molecules that typically develop H-bonds to bind to the minor groove of DNA. PAs are of interest because they can be designed to recognize DNA sequences. PAs have numerous biomedical applications in areas like regulation of gene expression and antimicrobial activity. Specifically, polyamide UMSL1011 (a polyamide synthesized in Dr. Bashkin's lab) inhibits replicating vesicular stomatitis virus (VSV) by binding the viral RNA inside the nucleocapsid, as indicated by research at Professor Ming Luo's lab at Georgia State University. However, some reports have revealed that polyamides have a low affinity for “simple” double-stranded RNA. Nevertheless, …

Increasing Adherence Of Pump Integration With Electronic Medical Record Through Simulation, Judi Reeves

Dissertations

Problem: Intravenous (IV) medication errors account for one-third of the medication errors made by nurses in the United States. A measure to combat medication errors is the development of IV pump integration where the IV pump is electronically connected to the electronic medical record (EMR). With IV pump integration, the nurse is responsible for turning on the pump, scanning the medication and the IV pump, and confirming in the EMR. Human error is removed when the IV pump integration system automatically programs and starts the IV pump. This is a technical system which requires the nurse to have expertise in …

Coronavirus Update 4-23-2021, The Coronavirus Planning Team

University Briefings & Virtual Events

Today’s topic is vaccination. Our second SHU-dedicated vaccination clinic is Sunday and there are plenty of appointments available. The clinic is open to everyone in the SHU community.

Integration Of Evidence Across Human And Model Organism Studies: A Meeting Report., Rohan H C Palmer, Emma C Johnson, Hyejung Won, Renato Polimanti, Manav Kapoor, Apurva Chitre, Molly A. Bogue, Chelsie E Benca-Bachman, Clarissa C Parker, Anurag Verma, Timothy Reynolds, Jason Ernst, Michael Bray, Soo Bin Kwon, Dongbing Lai, Bryan C Quach, Nathan C Gaddis, Laura Saba, Hao Chen, Michael Hawrylycz, Shan Zhang, Yuan Zhou, Spencer Mahaffey, Christian Fischer, Sandra Sanchez-Roige, Anita Bandrowski, Qing Lu, Li Shen, Vivek M. Philip, Joel Gelernter, Laura J Bierut, Dana B Hancock, Howard J Edenberg, Eric O Johnson, Eric J Nestler, Peter B Barr, Pjotr Prins, Desmond J Smith, Schahram Akbarian, Thorgeir Thorgeirsson, David O Walton, Erich Baker, Daniel Jacobson, Abraham A Palmer, Michael Miles, Elissa J Chesler, Jake Emerson, Arpana Agrawal, Maryann Martone, Robert W Williams

Faculty Research 2021

The National Institute on Drug Abuse and Joint Institute for Biological Sciences at the Oak Ridge National Laboratory hosted a meeting attended by a diverse group of scientists with expertise in substance use disorders (SUDs), computational biology, and FAIR (Findability, Accessibility, Interoperability, and Reusability) data sharing. The meeting's objective was to discuss and evaluate better strategies to integrate genetic, epigenetic, and 'omics data across human and model organisms to achieve deeper mechanistic insight into SUDs. Specific topics were to (a) evaluate the current state of substance use genetics and genomics research and fundamental gaps, (b) identify opportunities and challenges of …

A Capstone In Education: Current Challenges For Occupational Therapist Clinicians Transitioning To Role Of Academician, Jacie Schneider

Department of Occupational Therapy Entry-Level Capstone Projects

The doctoral capstone I participated in for my entry-level Doctor of Occupational Therapy program was in a focus area of education with a mentor who was a professor in a master’s program. I supported my mentor in her role as a professor of a physical dysfunction intervention course and had the opportunity to present a module to students on wheelchair seating interventions. Using experience gained during my capstone as well as information learned during the review of literature, I created a guide for OTs interested in making the transition into academia to meet the capstone project requirement.

Doctoral Capstone Experience In Program And Policy Development- Selah Freedom, Ashley N. Jones

Department of Occupational Therapy Entry-Level Capstone Projects

Child trafficking has been reported in all 50 states and affects more than 2 million children each year (Guardian Group, 2021). Involvement in human trafficking at a young age induces trauma that has a lasting effect on the victim’s personality and coping skills. A review of literature confirmed a need for more support of the use of occupational therapy with sex trafficking survivors. Despite support for the implementation of occupational therapy in similar trauma populations like domestic violence, homelessness, post-traumatic stress disorder, and disaster survivors, there is limited literature supporting the use of OT with human trafficking survivors (Gorman & …

The Influence Of Technology On A Child's Mental And Physical Functions, Rhonda Steere

MOT Student Capstones

The purpose of this project was to research and analyze various literature to determine the strengths and weaknesses of how the use of technology affects the child's occupational performance. This was done by creating a pre-questionnaire to learn about a child's daily use of technology and about a child's non-use time with technology. Results showed that the majority of children utilized some form of technological device or devices between six to nine hours a day with the majority of time being used for educational content. However, the majority of children were either not supervised or had supervision no longer than …

Quantitative Analysis Of Research On Artificial Intelligence In Retinopathy Of Prematurity, Ranjana Agrawal, Manasi Anup Agrawal, Sucheta Kulkarni, Ketan Kotecha, Rahee Walambe

Library Philosophy and Practice (e-journal)

Retinopathy of Prematurity (ROP) is a disease of the eye and a potential source of blindness in low birth weight preterm infants. It is preventable if diagnosed and treated on time. Artificial Intelligence (AI) has played an important role in developing automated screening systems to assist medical experts. There are many traditional literature review articles available that focus on the scientific content of ROP-AI. The researchers also require a bibliometric analysis to become acquainted with the competing groups and new trends in this field. This paper gives a brief overview of ROP and AI systems for ROP screening with a …

2021-04-23_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. It is updated Monday - Saturday.
This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) and rapid virus antigen detection point of …

2021-04-23_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

Effects Of Endogenous Angiotensin Ii On Abdominal Aortic Aneurysms And Atherosclerosis In Angiotensin Ii-Infused Mice, Masayoshi Kukida, Hisashi Sawada, Satoko Ohno-Urabe, Deborah A. Howatt, Jessica J. Moorleghen, Marko Poglitsch, Alan Daugherty, Hong S. Lu

Saha Cardiovascular Research Center Faculty Publications

No abstract provided.

Depression In Women Migrants Living In Slums In North India, Ram Lakhan, Manoj Sharma

Environmental & Global Health Faculty Research

No abstract provided.

Impact Of A Telephone-Based Care Management Program On Health Outcomes For Patients With Type 2 Diabetes And Hypertension, Abbegail Miller

DNP Projects

Background: Type 2 diabetes mellitus (T2DM) and hypertension (HTN) were the 7th leading cause of death in the United States, accounting for over 160,000 deaths annually. Complications related to T2DM and HTN are preventable with lifestyle modifications and medications. However, research has shown that lack of patient self-management, poor medication adherence, and physician time restraints limit disease improvement. A telephone-based care management program (CMP) provides a solution to meeting patient needs. Purpose: The purpose of this scholarly project was to evaluate individual biomarkers for glycemic and HTN control, as well as self-monitoring of blood glucose (SMBG) over one year of …

Self-Reliance And Self-Efficacy As Determinants Of Mental Health Treatment Seeking Intention In A Sample Of Student Service Members/Veterans, Leigh Holdsambeck

DNP Projects

Problem Statement: High rates of mental illness and poor treatment seeking have plagued the military for decades. As an organization that demands resilience, sacrifice, strength, and courage from its members, many servicemembers develop deep-seated self-reliance and self-efficacy. Though essential in many critical situations, these traits often complicate a servicemember's willingness to seek care for a mental health concern. Student servicemembers/veterans (SSM/Vs) are at an increased risk for poor mental health outcomes owing to the compounded stressors of military service and academia. Purpose: To measure the impact of elements of military service, namely self-reliance and self-efficacy, on mental health …

Dietary Strawberries Improve Cardiometabolic Risks In Adults With Obesity And Elevated Serum Ldl Cholesterol In A Randomized Controlled Crossover Trial, Arpita Basu, Kenneth Izuora, Nancy M. Betts, Jefferson W. Kinney, Arnold M. Salazar, Jeffrey L. Ebersole, R. Hal Scofield

Kinesiology and Nutrition Sciences Faculty Research

Background and aims: Dietary berries, such as strawberries, are rich in bioactive compounds and have been shown to lower cardiometabolic risk. We examined the effects of two dietary achievable doses of strawberries on glycemic control and lipid profiles in obese adults with elevated serum LDL cholesterol (LDL-C). Methods: In this 14-week randomized controlled crossover study, participants were assigned to one of the three arms for four weeks separated by a one-week washout period: control powder, one serving (low dose: 13 g strawberry powder/day), or two-and-a-half servings (high dose: 32 g strawberry powder/day). Participants were instructed to follow their usual diet …

An Annual Training Plan For Collegiate Dance, Ashley R. German

Honors Thesis

The focus of this thesis is on developing an annual resistance training plan for collegiate dance with no test subjects. This project provides biomechanical, physiological, and injury analysis of collegiate dance. Based on the analysis, a research-based, linear resistance training program for the University of South Dakota Dance Team was created. The resistance training program follows basic strength and conditioning principles including specificity, overload, and periodization. Additionally, exercise selection, order, volume, and intensity were prescribed based on standards set forth by the National Strength and Conditioning Association. Generally, from off-season to in-season, exercises moved from general to specific, along with …

Dnp Final Report: The Impact Of Mindfulness Training On Stress, Burnout, And Mindfulness, Denise Mcnulty

DNP Final Reports

Stress and burnout are endemic in the health care profession, and the transition to practice is associated with even more stress and anxiety for new graduate nurses (Boehm & Tse, 2013). Researchers have demonstrated that mindfulness-based interventions mitigate stress and burnout and improve the workplace environment and patient outcomes (Perla et al., 2017; van den Riet et al., 2018). This scholarly evidence-based practice project assessed the impact of integrating mindfulness training into an existing nurse residency program. The team measured burnout, stress, and mindfulness via an online survey at the beginning of the February 2020 residency cohort with repeat measures …

Association Of Hair Concentrations Of Antiretrovirals With Virologic Outcomes Among People Living With Hiv In Guangxi, China, Quan Zhang, Xiaoming Li Ph.D., Shan Qiao Ph.D., Shuaifeng Liu, Zhiyong Shen, Yuejiao Zhou

Faculty Publications

Background: Hair concentrations of antiretrovirals are an innovative and non-invasive method for measuring cumulative antiretroviral exposure and assessing long-term antiretroviral adherence. This study aimed to examine hair concentrations of antiretrovirals in relation to virologic outcomes among PLHIV in Guangxi, China.
Methods: Cross-sectional data of hair concentrations of antiretrovirals and HIV viral load were collected from 215 PLHIV in Guangxi, China. Multivariate logistic regression analyses were used to examine the association of hair concentrations of antiretrovirals with virologic outcomes.
Results: Of the 215 participants, 215, 67, and 163 PLHIV are receiving lamivudine, zidovudine, and efavirenz, respectively. Multivariate analysis revealed that hair …

Violence Against Healthcare Workers During The Covid-19 Pandemic: A Review Of Incidents From A Lower-Middle-Income Country, Omaima Anis Bhatti, Hareem Rauf, Namrah Aziz, Russell S. Martins, Javaid Khan

Medical College Documents

Background: Healthcare workers (HCWs) across the globe have met tremendous challenges during the COVID-19 (coronavirus disease 2019) pandemic, such as shortages of personal protective equipment, extensive work hours, and constant fear of catching the virus or transmitting it to loved ones. Adding on to the already existing burnout, an increase in incidents of violence and aggression against HCWs was seen in Pakistan and globally.
Objectives: Primarily to review cases of violence against HCWs in Pakistan, highlighting and comparing the instigating factors seen within the country and globally. Secondly, to enlist possible interventions to counter workplace violence in healthcare during a …

Further Fall Prevention, Kristen L. Janes

MSN Capstone Projects

Falls continue to occur in the acute care setting despite our best efforts. Decreased falls, increased patient safety, decreased cost, and decreased length of stays in the acute care setting are imperative. This is a benchmark study on the concept of an education pamphlet being presented to patients and family members educating on all fall precautions and interventions that are to be expected to be in use during their stay. Study also reflects fall interventions that are in use and have shown to decrease falls.

Fall Prevention: Remote Video Monitoring, Shawna Moser

MSN Capstone Projects

Patient safety is a top priority for all healthcare organizations, but as a healthcare facility, is everything, within the means of the facility, being done to ensure patient safety? Challenges exist for all healthcare organizations when faced with patient safety, but there it is a necessity for these healthcare organizations to overcome these challenges and protect their patient population. A common challenge within the acute care setting is the prevention of falls. “Falls during hospitalization harbor both clinical and financial outcomes” (Gringauz et al., 2017, p. 1). Research on fall interventions has shown that a multifocal approach is most effective …

The Influence Of Axial Myopia On Optic Disc Characteristics Of Glaucoma Eyes., Jasmin Rezapour, Christopher Bowd, Jade Dohleman, Akram Belghith, James A Proudfoot, Mark Christopher, Leslie Hyman, Jost B Jonas, Massimo A Fazio, Robert N Weinreb, Linda M Zangwill

Wills Eye Hospital Papers

This study characterizes differences in glaucomatous eyes with and without high axial myopia using custom automated analysis of OCT images. 452 eyes of 277 glaucoma patients were stratified into non (n = 145 eyes), mild (n = 214 eyes), and high axial myopia (axial length (AL) > 26 mm, n = 93 eyes). Optic disc ovality index, tilt and rotation angle of Bruch´s membrane opening (BMO) and peripapillary choroidal thickness (PCT) were calculated using automated and deep learning strategies. High myopic optic discs were more oval and had larger BMO tilt than mild and non-myopic discs (both p < 0.001). Mean PCT was thinnest in high myopic eyes followed by mild and non-myopic eyes (p < 0.001). BMO rotation angle, global retinal nerve fiber layer (RNFL) thickness and BMO-minimum rim width (MRW) were similar among groups. Temporal RNFL was thicker and supranasal BMO-MRW was thinner in high myopic eyes. BMO tilt and PCT showed moderate and temporal RNFL and nasal BMO-MRW showed weak but significant associations with AL in multivariable analyses (all p < 0.05). Large BMO tilt angle and thin PCT are characteristics of highly myopic discs and were not associated with severity of glaucoma. Caution should be exercised when using sectoral BMO-MRW and RNFL thickness for glaucoma management decisions in myopic eyes.

Bone Quality In Ckd Patients: Current Concepts And Future Directions – Part I, Kamyar Asadipooya, Mohamed Abdalbary, Yahya Ahmad, Elijah Kakani, Marie-Claude Monier-Faugere, Amr El-Husseini

Internal Medicine Faculty Publications

Background: There is ample evidence that patients with CKD have an increased risk of osteoporotic fractures. Bone fragility is not only influenced by low bone volume and mass but also by poor microarchitecture and tissue quality. More emphasis has been given to the quantitative rather than qualitative assessment of bone health, both in general population and CKD patients. Although bone mineral density (BMD) is a very useful clinical tool in assessing bone strength, it may underestimate the fracture risk in CKD patients. Serum and urinary bone biomarkers have been found to be reflective of bone activities and predictive of fractures …

Cyclin G2, A Novel Target Of Sulindac To Inhibit Cell Cycle Progression In Colorectal Cancer, Hongyou Zhao, Bin Yi, Zhipin Liang, Ches'nique N. Phillips, Hui Yi Lin, Adam I. Riker, Yaguang Xi

School of Medicine Faculty Publications

Sulindac has shown significant clinical benefit in preventing colorectal cancer progression, but its mechanism of action has not been fully elucidated. We have found that sulindac sulfide (SS) is able to inhibit cell cycle progression in human colorectal cancer cells, particularly through G1 arrest. To understand the underlying mechanisms of sulindac inhibitory activity, we have demonstrated that Cyclin G2 up-regulation upon SS treatment can substantially delay cell cycle progression by enhancing the transcriptional activity of FOXO3a in human colorectal tumor cells. MiR-182, an oncogenic microRNA known to inhibit FOXO3a gene expression, is also involved in the suppressive effect of SS …

Measuring Food Consumption Within A Foodrx Program, Katie Howell

Honors Theses

This pilot study set out to assess food consumption measures within the Charleston FoodRx program. Assessments made through this investigation aim to improve the Charleston program as well as provide suggestions for future programs. Charleston FoodRx provides enrolled households with fruits and vegetables in a supply intended to last for two weeks. These goals combine social and pharmaceutical science, by addressing barriers in food environment and insecurity, nutritional health, and preventative treatment. Though the idea behind FoodRx has existed prior to recent pilot programs, research behind FoodRx and its possible integration within the healthcare system lack published and replicable research …