Medicine and Health Sciences Commons^™

2021-04-27_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

2021-04-27_Michiganoverview_Covidlongtermcare, Michigan Department Of Health & Human Services

Michigan COVID-19 Long Term Care Data

The COVID Long Term Care Facilities page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173-526911--,00.html.

This report is created by the Michigan Department of Health & Human Services from data self-reported by long-term care facilities into EMResource. Data for all reporting facilities is posted weekly each Monday.

The information below represents COVID-19 data reported directly to MDHHS by licensed and operating Skilled Nursing, Home for the Aged and Adult Foster Care facilities (licensed to serve 13 or more individuals) in Michigan from January 1, 2020. All long-term care facilities additionally have an obligation to report COVID-positive residents and/or staff …

2021-04-27_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

The Mechanism Underlying Transient Weakness In Myotonia Congenita, Jessica H. Myers, Kirsten Denman, Chris Dupont, Ahmed A. Hawash, Kevin R. Novak, Andrew Koesters, Manfred Grabner, Anamika Dayal, Andrew A. Voss, Mark M. Rich

Neuroscience, Cell Biology & Physiology Faculty Publications

In addition to the hallmark muscle stiffness, patients with recessive myotonia congenita (Becker disease) experience debilitating bouts of transient weakness that remain poorly understood despite years of study. We performed intracellular recordings from muscle of both genetic and pharmacologic mouse models of Becker disease to identify the mechanism underlying transient weakness. Our recordings reveal transient depolarizations (plateau potentials) of the membrane potential to -25 to -35 mV in the genetic and pharmacologic models of Becker disease. Both Na + and Ca 2+ currents contribute to plateau potentials. Na + persistent inward current (NaPIC) through Na V 1.4 channels is the …

2021-04-27_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

Coronavirus Update 4-27-2021, The Coronavirus Planning Team

University Briefings & Virtual Events

Today, we just have a couple of reminders. We want to remind students and employees to please upload vaccination information to the student health portal or the through the HR questionnaire (for employees). This allows us to determine how close we are to herd immunity and will impact our decision-making regarding COVID protocols for the remainder of this semester and the fall.

The Use Of Automated Text Messaging As An Intervention For Smoking Cessation, Oluwasayo Sinkaiye

Evidence-Based Practice Project Reports

Tobacco smoking is a widespread problem that affects the adult population in the United States (U.S.). In 2018, about 14 of every 100 adults in the USA aged 18 years or older were cigarette smokers (Centers for Disease Control and Prevention [CDC], 2020). Tobacco smoking is associated with chronic disease conditions that have serious health implications including cancer, heart disease, diabetes, and chronic obstructive pulmonary disease (COPD) (CDC, 2020). The purpose of this evidence-based practice project (EBP) was to determine the effectiveness of an automated text messaging application (SmokefreeTXT) for smoking cessation in a primary care setting for adult cigarette …

Effectiveness Of An Online Intervention Combating Mental Health Stigma On Adolescent Help-Seeking Behaviors, Chelsea Krayecki

Counselor Education Capstones

Mental health stigma has been shown to be a barrier to seeking help for mental health concerns. This is especially true for adolescents due to important developmental characteristics. According to the World Health Organization (WHO) (2021), depression is one of the major causes of mental health concerns and disability among adolescents. In addition, the WHO (2021) also states that mental health conditions account for 16% of global burden of illness in people ages 10-19-years-old. The current pandemic has only increased these concerns, as social, emotional, and mental well-being has been impacted by the pandemic (Centers for Disease Control and Prevention, …

Categorization Of Orthologous Gene Clusters In 92 Ascomycota Genomes Reveals Functions Important For Phytopathogenicity, Daniel Peterson, Tang Li, Ana M. Calvo, Yanbin Yin

Food for Health: Publications

Phytopathogenic Ascomycota are responsible for substantial economic losses each year, destroying valuable crops. The present study aims to provide new insights into phytopathogenicity in Ascomycota from a comparative genomic perspective. This has been achieved by categorizing orthologous gene groups (orthogroups) from 68 phytopathogenic and 24 non-phytopathogenic Ascomycota genomes into three classes: Core, (pathogen or non-pathogen) group-specific, and genome-specific accessory orthogroups. We found that (i) ~20% orthogroups are group-specific and accessory in the 92 Ascomycota genomes, (ii) phytopathogenicity is not phylogenetically determined, (iii) group-specific orthogroups have more enriched functional terms than accessory orthogroups and this trend is particularly evident in phytopathogenic …

Combined Luteolin And Indole-3-Carbinol Synergistically Constrains Erα-Positive Breast Cancer By Dual Inhibiting Estrogen Receptor Alpha And Cyclin-Dependent Kinase 4/6 Pathway In Cultured Cells And Xenograft Mice, Xiaoyong Wang, Lijuan Zhang, Qi Dai, Hongzong Si, Longyun Zhang, Sakina E. Eltom, Hongwei Si

Human Sciences Faculty Research

The high concentrations of individual phytochemicals in vitro studies cannot be physiologically achieved in humans. Our solution for this concentration gap between in vitro and human studies is to combine two or more phytochemicals. We screened 12 phytochemicals by pairwise combining two compounds at a low level to select combinations exerting the synergistic inhibitory effect of breast cancer cell proliferation. A novel combination of luteolin at 30 μM (LUT30) and indole-3-carbinol 40 μM (I3C40) identified that this combination (L30I40) synergistically constrains ERα⁺ breast cancer cell (MCF7 and T47D) proliferation only, but not triple-negative breast cancer cells. At the same …

2021-04-27_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. It is updated Monday - Saturday.
This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) and rapid virus antigen detection point of …

Ciliary Extracellular Vesicles Are Distinct From The Cytosolic Extracellular Vesicles, Ashraf M. Mohieldin, Rajasekharreddy Pala, Richard Beuttler, James J. Moresco, John R. Yates Iii, Surya M. Nauli

Pharmacy Faculty Articles and Research

Extracellular vesicles (EVs) are cell‐derived membrane vesicles that are released into the extracellular space. EVs encapsulate key proteins and mediate intercellular signalling pathways. Recently, primary cilia have been shown to release EVs under fluid‐shear flow, but many proteins encapsulated in these vesicles have never been identified. Primary cilia are ubiquitous mechanosensory organelles that protrude from the apical surface of almost all human cells. Primary cilia also serve as compartments for signalling pathways, and their defects have been associated with a wide range of human genetic diseases called ciliopathies. To better understand the mechanism of ciliopathies, it is imperative to know …

Predicting Academic Success Using Grit And Academic Resiliency In College Freshmen, Julianna Boyle

Health and Kinesiology Theses

Background: The purpose of this study was to determine if there are other factors that could predict academic success. Specifically, is there an association between Grit and Academic Resiliency prior to the start of a semester and academic success (defined by GPAs) in college freshmen. This study also explored students’ experiences of high school, effects from the COVID-19 pandemic, perception about their journey through the beginning of their College freshmen year, and perception about success.

Methods: A mixed methods design was used. A quantitative survey was emailed to all incoming UT Tyler Freshmen students prior to the Fall …

Covid-19 Vaccine Acceptance Among College Students: A Theory-Based Analysis, Manoj Sharma, Robert E. Davis, Amanda H. Wilkerson

Environmental & Global Health Faculty Research

The severity and pervasiveness of the COVID-19 pandemic have necessitated the emer-gency use of COVID-19 vaccines. Three vaccines have been approved in the United States (USA). However, there is still some hesitancy in COVID-19 vaccine acceptability among some subgroups, including college students. While research is limited on vaccine acceptability behavior among college students, preliminary data suggests hesitancy as being high. This study aimed to explain the correlates of COVID-19 vaccine acceptance among college students who reported hesitancy toward the COVID-19 vaccine and those who did not using the initiation component of the multi-theory model (MTM) of health behavior change. Using …

A Systematic Review And Meta-Analysis On The Efficacy Of Repeated Transcranial Direct Current Stimulation For Migraine, Guoshuai Cai, Zhu Xia, Leigh Charvet, Feifei Xiao, Abhishek Datta, X Michelle Androulakis

Publications and Research

Purpose: Transcranial direct current stimulation (tDCS) may have therapeutic potential in the management of migraine. However, studies to date have yielded conflicting results. We reviewed studies using repeated tDCS for longer than 4 weeks in migraine treatment, and performed meta-analysis on the efficacy of tDCS in migraine.

Methods: In this meta-analysis, we included the common outcome measurements reported across randomized controlled trials (RCTs). Subgroup analysis was performed at different post-treatment endpoints, and with different stimulation intensities and polarities.

Results: Five RCTs were included in the quantitative meta-analysis with a total of 104 migraine patients. We found a significant reduction of …

Va&P: Creation Of A Patient Appointment And Scheduling System To Reduce Wait Times, Roxanne Canicula Msn, Rn, Ocn, Stacy Gray Msn, Rn, Ne-Bc, Fnp-C, Catherine Noche Msn, Rn, Cnl, Ccrn, Marichelle Espiritu Msn, Rn, Cnn

Education Week Poster Showcase 2021

No abstract provided.

Cultural Awareness In The Health Care Team, Josna Kurian Bsn, Rn, Ocn

Education Week Poster Showcase 2021

Outpatient, Medical Oncology - Sugarland

Decreasing Hospital Acquired Pressure Injuries Through Interdisciplinary Team Engagement, Alice Hung Rn, Bsn, Cmsrn, Cfcn, Cwocn, Yvette Ong Ms, Bsn, Rn, Ocn, Ne-Bc, Klaire Angeli Coluso Rn, Msn, Cwocn, Lini Abraham Rn, Bsn, Cwocn, Jamie Belardo Bsn, Rn, Cwocn, Jeanine Hanohano Bsn, Rn, Cwocn, Christie Cabato Bsn, Rn, Cwocn, Paul Castro Bsn, Rn, Cwocn, Diane Cho Bsn, Rn, Cwocn, Chi Eziakonwa Msn, Rn, Cwocn, Jarrod Vance Bsn, Rn, Cwocn, Sugitha Dickson Bsn, Rn, Cwocn, Iowa Modequillo Bsn, Rn, Cwocn

Education Week Poster Showcase 2021

Department of Wound, Ostomy & Continence Nursing

Department of Nursing

Fall Prevention Using A Standardized K-Card Process, Falguni Shah Msn, Rn, Cms-Rn, Cnl, Anna Varghese Dnp, Msn, Rn, Ocn

Education Week Poster Showcase 2021

People's Choice winner in the 2021 Education Week Poster Competition

Department of Nursing

Department of Nursing Education

Diabetes In The Oncology Setting Webinar Series, Jennifer Williams, Denise A. Palma, Michael Rizk Msn, Aprn, Fnp-C, Bc-Adm

Education Week Poster Showcase 2021

Department of Endocrine Neoplasia and Hormonal Disorders

Genetic Correlates In Patients With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Treated With Hyper-Cvad/Hyper-Cmad Plus Dasatinib Or Hyper-Cvad Plus Ponatinib, Yuya Sasaki Md, Phd, Hagop Kantarjian Md, Nicholas J. Short Md, Farhad Ravandi Md, Marina Konopleva Md, Phd, Guillermo Garcia-Manero Md, Andrew Futreal, Feng Wang, Koichi Takahashi Md, Phd, Elias Jabbour Md

Education Week Poster Showcase 2021

Department of Leukemia Research

Department of Leukemia

Department of Genomic Medicine

Askmdanderson Remote Innovative Comprehensive Call Center, Janice Finder Bsn, Msn, Rn, Ashlyn Proske Bs, Marilyn Callahan Ba, Ninette Thomas As, Bs, Mha, Nadine Njoku, Maxwell Lewis Bs, Irene Yaafi Bs, Tiffany Terry

Education Week Poster Showcase 2021

askMDAnderson

Inhibition Of Nr2b Phosphorylation Reduces Proton Therapy-Induced Cytotoxicity And Bystander Killing Effect, Yuan-Hao Lee Phd, Fada Guan Phd

Education Week Poster Showcase 2021

Department of Radiation Physics, Division of Radiation Oncology

Maintaining Outcomes With Virtual Delivery Of Pharmacy Grand Rounds, Amber Rexwinkle Pharmd, Med, Bcop, Bonnie Butler Med, Nephy George Pharmd, Diane Hecht Pharmd, Med, Chcp, Tiffany Kofroth Cpht-Adv, Cspt, Phtr, Marisa Mendoza Pharmd, Chcp, Cphq, Rebecca Tirrell Mls

Education Week Poster Showcase 2021

Second place winner in the 2021 Education Week Poster Competition

Division of Pharmacy, Pharmacy Continuing Education Programs

The Benefit Of A Blended Education Approach In Patient Access Representative (Par) Training: Didactic And Simulation, Daryl Anildes-Gumban Msn, Rn, James Cavalier, Jr. Phd, Rn, Jennifer Mills Msn, Rn, Judie Nelson, Caranza Johnson, Tracy Renick, Diane Bodurka

Education Week Poster Showcase 2021

Division of Education and Training

Indole-3-Carbinol-Dependent Aryl Hydrocarbon Receptor Signaling Attenuates The Inflammatory Response In Experimental Necrotizing Enterocolitis, Lila S Nolan, Belgacem Mihi, Qingqing Gong, Jamie M Rimer, Shay S Bidani, Sarah E Gale, Martin Goree, Elise Hu, Wyatt E Lanik, Elizabeth Huang, Jennifer K Bando, Angela N Lewis, Marie L Laury, Misty Good, Et Al.

2020-Current year OA Pubs

Necrotizing enterocolitis (NEC) causes significant morbidity and mortality in premature infants; therefore, the identification of therapeutic and preventative strategies against NEC remains a high priority. The ligand-dependent transcription factor aryl hydrocarbon receptor (AhR) is well known to contribute to the regulation of intestinal microbial communities and amelioration of intestinal inflammation. However, the role of AhR signaling in NEC is unclear. Experimental NEC was induced in 4-d-old wild-type mice or mice lacking AhR expression in the intestinal epithelial cells or AhR expression in CD11c

The Endocannabinoid Anandamide Attenuates Acute Respiratory Distress Syndrome By Downregulating Mirna That Target Inflammatory Pathways, Muthanna Sultan, Hasan Alghetaa, Amirah Mohammed, Osama A. Abdulla, Paul J. Wisniewski, Narendra Singh, Prakash Nagarkatti, Mitzi Nagarkatti

Faculty Publications

Acute respiratory distress syndrome (ARDS) is defined as a type of respiratory failure that is caused by a variety of insults such as pneumonia, sepsis, trauma and certain viral infections. In this study, we investigated the effect of an endocannabinoid, anandamide (AEA), on ARDS induced in the mouse by Staphylococcus Enterotoxin B (SEB). Administration of a single intranasal dose of SEB in mice and treated with exogenous AEA at a dose of 40 mg/kg body weight led to the amelioration of ARDS in mice. Clinically, plethysmography results indicated that there was an improvement in lung function after AEA treatment accompanied …

Efficiency With Covid-19: Home Vs. Dillon’S Rule States, Jason Kolb

Political Science Theses and Capstones

How does a state measure success when dealing with a pandemic like Covid-19? Can Dillon’s Rule keep their citizens happy and protected during a pandemic better then Home Rule? When local governments wait for the state to create policies, is this the best option for the state? Data will show a trend that states with a higher preemption rate have kept the death rate lower when dealing with the Covid-19 pandemic

Effects Of Tobacco Product Type And Characteristics On Appeal And Perceived Harm: Results From A Discrete Choice Experiment Among Guatemalan Adolescents, Jose Monzón, Farahnaz Islam, Sophia Mus, Jim Thrasher, Joaquin Barnoya

Faculty Publications

Guatemala is one of the few countries where both heated tobacco products (HTPs) and electronic cigarettes (ecigarettes) remain unregulated. We used a discrete choice experiment (DCE) administered to 2038 high school students to assess how tobacco product attributes influence their appeal among Guatemalan adolescents. Participants were randomly assigned to evaluate 4 of 32 contrasting sets, each containing 3 packs (1 of each product type). Experimental manipulations included: product type, brand, nicotine content and flavor. Participants then indicated which product they were most and least interested in trying and would be most and least harmful to their health. Conditional logistic regression …

How Gata3 Affects Neuronal Survival In The Inner Ear, Hiba Ahmad

Honors Theses

Broadly speaking, Gata3 is a transcription factor involved in neurosensory specification and hair cell differentiation. Previous studies have shown that Gata3 null mutants do not develop neurons, so Gata3 appears to be necessary for neuronal survival. To better understand the role of Gata3 in spiral ganglion neurons of the inner ear, a Neurod1-cre model was used to conditionally knock out Gata3 at E9-E9.5, the timepoint when neuroblasts first begin to delaminate from the otic placode. The mutants used in this study were Nd1-cre: Gata3 f/f mutants. In situ was performed to determine gene expression within the cochlea, and immunohistochemistry was …