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2021

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Full-Text Articles in Medicine and Health Sciences

Feedback-Informed Treatment (Fit) Data Demonstrates The Importance Of The First Session With A Client, Huma Bashir, Josephine F. Wilson, Greta H. Meyer Dec 2021

Feedback-Informed Treatment (Fit) Data Demonstrates The Importance Of The First Session With A Client, Huma Bashir, Josephine F. Wilson, Greta H. Meyer

Human Services Faculty Publications

Feedback Informed Treatment (FIT) is a client-driven, outcome-based approach to enhance treatment outcomes. FIT data from 2,283 clients served by 80 counselors working at nine participating agencies were collected and analyzed to measure client response. These data included Outcome Rating Scale (ORS) scores obtained at the beginning of each session and Session Rating Scale (SRS) scores obtained at the end of each session. TotalORS and Total SRS scores at the first session for the individuals who failed to improve from first to last sessions were significantly lower than the Total ORS and Total SRS scores at the first session for …


When It Hits The Fan, Does Network Management Matter? : A Study On Policy Shocks And The Production And Delivery Of Public Goods And Services By Service Delivery Networks, Jennie Rhodes Law Dec 2021

When It Hits The Fan, Does Network Management Matter? : A Study On Policy Shocks And The Production And Delivery Of Public Goods And Services By Service Delivery Networks, Jennie Rhodes Law

Legacy Theses & Dissertations (2009 - 2024)

EXECUTIVE SUMMARYFor decades public administration and management scholars have conceptualized organizational networks as solutions to failures of markets and hierarchies (see, for example, Goldsmith and Eggers 2005; Osborne and Gaebler 1992). Relationships among organizations or actors within a network are framed positively as channels through which human, financial, and knowledge resources flow to address complex or “wicked” social problems (see, for example, Rittel and Weber, 1973). However, recent scholarship has sought to pull the curtain back and identify the pitfalls of networked arrangements for public service delivery (see, for example, O’Toole & Meier, 2006; O’Toole & Meier, 2004). Such studies …


Nicu Nurse Burnout: The Influence Of Moral Distress, Compassion Fatigue, And Spirituality On Burnout In Neonatal Intensive Care Unit Nurses, Lucia D'Andrea Dec 2021

Nicu Nurse Burnout: The Influence Of Moral Distress, Compassion Fatigue, And Spirituality On Burnout In Neonatal Intensive Care Unit Nurses, Lucia D'Andrea

Undergraduate Theses

Nurses face a multitude of interpersonal and individual expectations, challenges, and hardships every day of their profession. These experiences accumulate and can lead to burnout. This is especially true for nurses in Neonatal Intensive Care Units (NICUs) who care for infants struggling with prematurity, congenital diseases, withdrawal, and more, all while working closely with grieving parents. This thesis specifically focuses on research discussing moral distress, compassion fatigue, and spirituality as variables associated with the experience of burnout. A critical review of current literature revealed patterns and inconsistencies in the relationships between these factors. Workplace Stressors and moral distress were found …


Adverse Childhood Experiences And Social Determinants Of Health In Relation To Pediatric Intensive Care Unit Admissions, Kasey Davis Dec 2021

Adverse Childhood Experiences And Social Determinants Of Health In Relation To Pediatric Intensive Care Unit Admissions, Kasey Davis

The Eleanor Mann School of Nursing Undergraduate Honors Theses

This literature review was conducted in order to examine the correlation between adverse childhood experiences (ACEs), social determinants of health and pediatric intensive care unit (PICU) admissions. Oftentimes, those admitted as patients in the PICU come from homes in which social determinants of health, such as poverty and lack of access to healthcare, and ACEs, such as abuse and neglect, are prevalent. Systematic studies of existing literature and experience in the hospital setting revealed the ways in which these conditions often cause children to reach such poor health conditions that they must be admitted to the PICU. In order to …


The Effects Of Doula Care On Birth Outcomes And Patient Satisfaction In The United States, Lynae Carlson Dec 2021

The Effects Of Doula Care On Birth Outcomes And Patient Satisfaction In The United States, Lynae Carlson

The Eleanor Mann School of Nursing Undergraduate Honors Theses

The visitor policies related to the COVID-19 pandemic limited doula care and called into question the importance of doulas in the birth process. While the Cochrane Systematic Review presents compelling evidence of the benefits of continuous birth support on outcomes ranging from shorter labors to higher 5-minute Apgar scores, there are gaps in literature that exclusively focus on continuous support from doulas. The literature review aims to determine both qualitative and quantitative outcomes of doula care on the mother and baby during the labor and post-partum periods, focusing on specific aggregates, such as adolescents, women with low incomes, and women …


Breastfeeding In Public And The Impact Of Mass Media On Breastfeeding: An Expanded Literature Review, Hannah Underwood Dec 2021

Breastfeeding In Public And The Impact Of Mass Media On Breastfeeding: An Expanded Literature Review, Hannah Underwood

The Eleanor Mann School of Nursing Undergraduate Honors Theses

The choice a mother makes to breastfeed or to formula feed is a hotly debated topic in the United States today. The benefits of breastfeeding for both mother and baby are undeniable, but breastfeeding is difficult for some due to a plethora of barriers, notably a lack of social support. This literature review evaluates attitudes towards breastfeeding in public and how varying mass media formats can impact perceptions of breastfeeding and potentially breastfeeding implementation. Twenty articles with both qualitative and quantitative data were obtained from Medline Complete EBSCO Host and PubMed for a comprehensive analysis. Among 283 total articles retrieved, …


Implementing 2nd Milk’S Use Of The World Health Organization Standardized Growth Charts To Better Track The Growth And Development Of The Malnourished And Orphaned Infants In Their Supplemental Nutrition Program In Malawi, Allie Wycoff Dec 2021

Implementing 2nd Milk’S Use Of The World Health Organization Standardized Growth Charts To Better Track The Growth And Development Of The Malnourished And Orphaned Infants In Their Supplemental Nutrition Program In Malawi, Allie Wycoff

The Eleanor Mann School of Nursing Undergraduate Honors Theses

This article considers the history and implications of the World Health Organization (WHO) standardized growth charts as well as the significant impact that growth chart utilization may have on 2ndMilk’s ability to understand and track the nutritional status of the malnourished orphaned infants in their formula program. Specifically, this literature review examines whether or not the WHO growth charts are a meaningful tool for 2ndMilk to adopt into their monthly baby assessments. The WHO growth charts are calibrated to express an accepted international “norm” for what an adequately nourished child looks like. In a recent service-learning …


The Effects Of Social Determinants On Renal Care Among Eskd Patients In The Philippines: Rural Vs. Urban Areas, Melanie Rojas Dec 2021

The Effects Of Social Determinants On Renal Care Among Eskd Patients In The Philippines: Rural Vs. Urban Areas, Melanie Rojas

Nursing | Senior Theses

From a Public Health Nursing (PHN) perspective, populations who are diagnosed with chronic disease or illness are the most vulnerable to end-stage kidney disease (ESKD) or end-stage renal disease (ESRD). The International Society of Nephrology (ISN) states that the mortality rate for ESKD amounts to roughly 7 million individuals worldwide. In examining causes of ESKD throughout both history and the lifespan, high mortality rates are attributed to the lack of access to life-sustaining therapies such as dialysis or transplantation. The lack of access to therapy or healthcare services has been an immense Public Health crisis in the last few decades. …


Mental Health And Adolescents: The Impact Of Social Isolation In Adolescents During The Covid-19 Pandemic, Gabriella Aguinaldo Dec 2021

Mental Health And Adolescents: The Impact Of Social Isolation In Adolescents During The Covid-19 Pandemic, Gabriella Aguinaldo

Nursing | Senior Theses

In early 2020, the coronavirus pandemic, first detected in late 2019, afflicted the world. The disease associated with the virus became known as COVID-19. COVID-19 was recognized as a highly contagious and deadly disease. In California, United States, COVID-19 was detected in February and the first shelter-in-place orders were ordered by the counties and state, which forced children and adults to stay at home and attend school and work virtually. Shelter-in-place orders were quickly implemented around the world.

As the world began this sudden switch in lifestyle, many were concerned for the mental health and safety of themselves and their …


Effects Of Dance/Movement Therapy On Pediatric Oncology Patients, Kaitlin Callorina Dec 2021

Effects Of Dance/Movement Therapy On Pediatric Oncology Patients, Kaitlin Callorina

Nursing | Senior Theses

Pediatric nursing specializes in caring for patients from birth through adolescence; therefore, pediatric nursing can be spiritually challenging but rewarding. This thesis will explore the questions:

  • Does dance/movement therapy have the potential to improve the quality of life for children who are diagnosed with cancer?
  • How does dance/movement therapy change the quality of life in pediatric cancer patients throughout their diagnosis and treatment?

To aid in answering these questions, this thesis will examine various research articles related to dance/movement therapy and other creative arts therapy as complementary medicine and integrating the activity into nursing care. Children who are diagnosed and …


The Physiological Benefits Of A Plant-Based Diet On Cardiovascular Health, Jenevieve Petray Dec 2021

The Physiological Benefits Of A Plant-Based Diet On Cardiovascular Health, Jenevieve Petray

Nursing | Senior Theses

Cardiovascular disease (CVD) is increasingly more prevalent in today’s society and is attributed to an alarming percentage of American hospitalizations and deaths. Americans are unhealthier than ever before, and the main contributor is the Western diet. Diet is a double-edged sword that can offer benefits or detriments to one’s health. CVD encompasses numerous diagnoses originating from various underlying physiological alterations. These alterations are downstream effects of increased body weight and BMI, increased cholesterol levels, decreased insulin sensitivity and increased arterial plaque buildup. Research shows that a plant-based diet has the potential to manage and reverse all fundamental physiological alterations that …


Disparities Among Black Women In Maternal Health, Josefina Teresa Estrada Dec 2021

Disparities Among Black Women In Maternal Health, Josefina Teresa Estrada

Nursing | Senior Theses

The literature shows that Black women face many disparities in terms of health care access and the quality of care. These obstacles could negatively affect the health of the mother and their child. This paper includes a literature review and proposed research study. The objective of this research study is to identify the outcomes of Black women compared to White women and other women of color in terms of maternal health. A literature review is provided in order to identify how race affects the following factors: obstacles that limit access to healthcare, rates of obtaining prenatal care, postpartum outcomes and …


Discerning The True Dilemma Of Diabetes Among Hispanics, Ramon Ponce Dec 2021

Discerning The True Dilemma Of Diabetes Among Hispanics, Ramon Ponce

Nursing | Senior Theses

There is a common misconception that the primary role of nurses is to follow doctors’ orders and treat patients who are currently suffering and experiencing pain. Chronic illnesses such as diabetes can be prevented and better managed if the population who is greatest at risk is better informed and educated on the disease. Different cultures and ethnicities have different foods that unfortunately puts them at risk to get diabetes. Hispanics typically follow a diet that is high in carbohydrates, saturated fats, and sugars that greatly contribute to the development of diabetes. Often, Hispanics are not educated enough to comprehend the …


Increased Use Of Opioids Perioperatively Leads To Unmanaged Postoperative Pain, Halida Sehic Dec 2021

Increased Use Of Opioids Perioperatively Leads To Unmanaged Postoperative Pain, Halida Sehic

Nursing | Senior Theses

Background: Total knee and total hip joint arthroplasty are two frequently preformed surgeries, with 5.2 million total knee arthroplasties performed the United States between the year 2000 and 2010 (Williams et al., 2015). Opioids are widely used to manage pain for patients undergoing total joint arthroplasty. However, use of opioids is associated with undesirable adverse effects, such as nausea and respiratory depression, (Johnson et al., 2011). In postoperative patients following total joint replacement, 75 % of the patients complain of inadequately controlled moderate to severe pain (De Luca et al., 2018). Increased use and overprescribing increase tolerance to opioids …


The Yearly Financing Need Of Providing Paid Maternity Leave In The Informal Sector In Indonesia, Adiatma Y. M. Siregar, Pipit Pitriyan, Donny Hardiawan, Paul Zambrano, Mireya Vilar-Compte, Graciela Ma Teruel Belismelis, Meztli Moncada, David Tamayo, Grace Carroll, Rafael Perez-Escamilla, Roger Mathisen Dec 2021

The Yearly Financing Need Of Providing Paid Maternity Leave In The Informal Sector In Indonesia, Adiatma Y. M. Siregar, Pipit Pitriyan, Donny Hardiawan, Paul Zambrano, Mireya Vilar-Compte, Graciela Ma Teruel Belismelis, Meztli Moncada, David Tamayo, Grace Carroll, Rafael Perez-Escamilla, Roger Mathisen

Department of Public Health Scholarship and Creative Works

Background: The economic cost of not breastfeeding in Indonesia is estimated at US$1.5–9.4 billion annually, the highest in South East Asia. Half of the 33.6 million working women of reproductive age (WRA) in Indonesia (15–49 years) are informal employees, meaning they are working as casual workers or they are self-employed (small scale business) and assisted by unpaid/family worker(s). No specific maternity protection entitlements are currently available for WRA working informally in Indonesia. This study aims to estimate the financing need of providing maternity leave cash transfer (MCT) for WRA working in the informal sector in Indonesia. Method: The costing methodology …


Breastfeeding Media Coverage And Beliefs During The Covid-19 Pandemic In Mexico: Implications For Breastfeeding Equity, Mireya Vilar-Compte, P. Gaitán‐Rossi, E. C. Rhodes, V. Cruz‐Villalba, R. Pérez‐Escamilla Dec 2021

Breastfeeding Media Coverage And Beliefs During The Covid-19 Pandemic In Mexico: Implications For Breastfeeding Equity, Mireya Vilar-Compte, P. Gaitán‐Rossi, E. C. Rhodes, V. Cruz‐Villalba, R. Pérez‐Escamilla

Department of Public Health Scholarship and Creative Works

Background: Because breastfeeding offers short- and long- term health benefits to mothers and children, breastfeeding promotion and support is a public health priority. Evidence shows that SARS-CoV-2 is not likely to be transmitted via breastmilk. Moreover, antibodies against SARS-CoV-2 are thought to be contained in breastmilk of mothers with history of COVID-19 infection or vaccination. WHO recommends direct breastfeeding as the preferred infant feeding option during the COVID-19 pandemic, even among women with COVID-19; but conflicting practices have been adopted, which could widen existing inequities in breastfeeding. This study aims to describe how information about breastfeeding was communicated in Mexican …


The Interactions Between Oral Biofilms, Antibiotic Resistance, And Dentistry, Maxine Taylor Dec 2021

The Interactions Between Oral Biofilms, Antibiotic Resistance, And Dentistry, Maxine Taylor

Honors Projects

Antibiotic resistance is a pressing concern that demands further action to reduce and develop new countermeasures. Antibiotic resistance impacts all fields of health and medicine, including dentistry. Many of the preventive and restorative dental procedures are due to a bacterial cause. Knowledge of oral biofilm development mechanisms and the interactions and relationships between oral microbiota is necessary to combat the spread of antibiotic resistance and develop more effective dental treatments. Exploring how the oral microbiomes and their treatments impact the health of the rest of the body is another important consideration since dentistry is part of the general healthcare system. …


Systematic Review Of The Association Between Cultural Competence And The Quality Of Care Provided By Health Personnel, Amanda Skipworth Dec 2021

Systematic Review Of The Association Between Cultural Competence And The Quality Of Care Provided By Health Personnel, Amanda Skipworth

Honors Projects

The purpose of this research project is to determine if a relationship exists between cultural competence and the quality of care administered by health care professionals. Challenges with providing care begin to arise when cultural barriers limit the provider’s ability to provide adequate care. In the past, many professionals have struggled with how to approach patients from diverse backgrounds and this discomfort continues to grow. With minority populations in the United States rapidly growing, it is largely beneficial for these professionals to understand and be aware of the varying cultures seeking medical care. To address the research question, a systematic …


Examining An Intersection Of Environmental Justice And Covid-19 Risk Assessment: A Review, Ashley Ellis Dec 2021

Examining An Intersection Of Environmental Justice And Covid-19 Risk Assessment: A Review, Ashley Ellis

Honors Theses

This study views the risks associated with the novel coronavirus (COVID-19) as an environmental injustice issue due to the connection between existing environmental disparities and the disproportional negative impacts brought upon by the virus. The social and health determinants attributed to those environmental disparities have traditionally been evaluated as individual risk factors, an approach that fails to gauge the complexity of an environmental injustice issue. This study employs the emerging theory of intersectionality, a belief that phenomena cannot be linked to one principal cause but instead an interconnected web of influences, in order to synthesize the multitude of factors believed …


Gut Permeability And Osteoarthritis, Towards A Mechanistic Understanding Of The Pathogenesis: A Systematic Review, Giorgio Guido, Guido Ausenda, Veronica Iascone, Emanuele Chisari Dec 2021

Gut Permeability And Osteoarthritis, Towards A Mechanistic Understanding Of The Pathogenesis: A Systematic Review, Giorgio Guido, Guido Ausenda, Veronica Iascone, Emanuele Chisari

Rothman Institute Papers

Osteoarthritis (OA) is the most common condition affecting human joints. Along with mechanical and genetic factors, low-grade inflammation is increasingly supported as a causal factor in the development of OA. Gut microbiota and intestinal permeability, via the disruption of tight junction competency, are proposed to explain a gut-joint axis through the interaction with the host immune system. Since previous studies and methods have underestimated the role of the gut-joint axis in OA and have only focussed on the characterisation of microbiota phenotypes, this systematic review aims to appraise the current evidence concerning the influence of gut permeability in the pathogenesis …


Senior Center Response To Covid-19: Mid-Year Operations 2021, Ceara Somerville, Caitlin Coyle, Jan Mutchler Dec 2021

Senior Center Response To Covid-19: Mid-Year Operations 2021, Ceara Somerville, Caitlin Coyle, Jan Mutchler

Center for Social and Demographic Research on Aging Publications

Senior centers/COAs in Massachusetts remained largely operational through the height of the COVID-19 pandemic, and continued to assist older adults in the community. With the introduction of a vaccine, return to ‘normal’ operations has become more feasible. By mid-2021, senior centers were returning to some in-person operations and continued adaptations for safety, including mask-wearing, limiting capacity, fewer walk-ins, and increased hand sanitization availability.


Expanding The Conceptualization Of Support In Low-Wage Carework: The Case Of Home Care Aides And Client Death, Emma K. Tsui, Marita Lamonica, Maryam Hyder, Paul Landsbergis, Jennifer Zelnick, Sherry Baron Dec 2021

Expanding The Conceptualization Of Support In Low-Wage Carework: The Case Of Home Care Aides And Client Death, Emma K. Tsui, Marita Lamonica, Maryam Hyder, Paul Landsbergis, Jennifer Zelnick, Sherry Baron

Publications and Research

Home care aides are a rapidly growing, non-standard workforce who face numerous health risks and stressors on the job. While research shows that aides receive limited support from their agency employers, few studies have explored the wider range of support that aides use when navigating work stress and considered the implications of these arrangements. To investigate this question, we conducted 47 in-depth interviews with 29 home care aides in New York City, focused specifically on aides’ use of support after client death. Theories of work stress, the social ecological framework, and feminist theories of care informed our research. Our analysis …


November / December 2021, Cindy Brooks, Randy Curry Dec 2021

November / December 2021, Cindy Brooks, Randy Curry

RURAL ROCKS

Rural Rocks, the Rural Health Network newsletter by the SWOSU College of Pharmacy.


Impact Of Xenobiotics On Neuronal Outcomes, Gabriela Henriquez Dec 2021

Impact Of Xenobiotics On Neuronal Outcomes, Gabriela Henriquez

Open Access Theses & Dissertations

Neurodegenerative diseases are a common affliction of the Central Nervous System. They are caused by age, genetics, and environmental factors. Alzheimer's disease, Parkinson's disease, Huntington's disease, and Amyotrophic Lateral Sclerosis are well-known among the host of neurodegenerative disorders, with Alzheimer's disease and Parkinson's disease being the leading pathologies across this canvas. It is known that the pathogenesis of neurodegenerative diseases is multifactorial due to the involvement of genetic mutations, radical-induced protein damage, abnormal aggregation of misfolded proteins, and the formation of amyloid deposits. The amyloid proteins in neurodegenerative disease include Tau and Amyloid (Aβ) in Alzheimer's disease and α-Synuclein in …


Associations Between Living On The Texas-Mexico Border, Drug Use, And Sexual Behaviors Among Sexual Minority Men During The First Shelter-In-Place Order Of The Coronavirus Pandemic, Nqobile Nzama Dec 2021

Associations Between Living On The Texas-Mexico Border, Drug Use, And Sexual Behaviors Among Sexual Minority Men During The First Shelter-In-Place Order Of The Coronavirus Pandemic, Nqobile Nzama

Open Access Theses & Dissertations

Background: There have been changes in drug use and sexual behaviors among sexual minority men since the coronavirus pandemic. At this time, there is not adequate literature focusing on the state of Texas. Aims and Objective: The aims of this secondary data analysis and exploratory study are to determine associations between sociodemographic characteristics and living on the Texas-Mexico border, drug use, sexual behaviors, and use of dating/hook-up apps among sexual minority men who completed the COVID-19 & You Survey conducted between May 1, 2020 to July 31, 2020, during the first shelter-in-place order of the Coronavirus pandemic. Hypotheses: The hypotheses …


Ecology Of Hantaviruses In Rodent Reservoirs And Their Early Innate Immune Responses In Human Model Systems, Evan Peter Williams Dec 2021

Ecology Of Hantaviruses In Rodent Reservoirs And Their Early Innate Immune Responses In Human Model Systems, Evan Peter Williams

Theses and Dissertations (ETD)

The spillover of zoonotic RNA viruses is responsible for a great deal of the disease outbreaks in human populations. These spillover events are set to continue due to anthropogenic and environmental changes that impact the distribution of these viruses. The viruses in the family Hantaviridae are classified as one of these emerging zoonotic RNA viruses. The spillover of the viruses in this family are responsible for two severe human diseases, hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). These viruses are distributed across the globe and are responsible for a large number of human disease cases with …


Parks And The Pandemic: A Scoping Review Of Research On Green Infrastructure Use And Health Outcomes During Covid-19, Megan Heckert, Amanda Bristowe Dec 2021

Parks And The Pandemic: A Scoping Review Of Research On Green Infrastructure Use And Health Outcomes During Covid-19, Megan Heckert, Amanda Bristowe

Geography & Planning Faculty Publications

Green infrastructure (GI) has long been known to impact human health, and many academics have used past research to argue for the potential importance of GI as a mechanism for maintaining or improving health within the context of the COVID-19 pandemic. This scoping review addresses the question: What evidence, if any, have researchers found of a relationship between green infrastructure use and health during the COVID-19 pandemic? Specifically, evaluating the (a) association of GI use with COVID-19 disease outcomes and (b) association of GI use with other health outcomes as impacted by the COVID-19 pandemic. Twenty-two studies were identified that …


The Alzheimer’S Disease Drug Development Landscape, Pieter Van Bokhoven, Arno De Wilde, Lisa Vermunt, Prisca S. Leferink, Sasja Heetveld, Jeffrey Cummings, Philip Scheltens, Everard G.B. Vijverberg Dec 2021

The Alzheimer’S Disease Drug Development Landscape, Pieter Van Bokhoven, Arno De Wilde, Lisa Vermunt, Prisca S. Leferink, Sasja Heetveld, Jeffrey Cummings, Philip Scheltens, Everard G.B. Vijverberg

Brain Health Faculty Research

Background: Alzheimer’s disease (AD) is a devastating neurodegenerative disease leading to dementia. The field has made significant progress over the last 15 years. AD diagnosis has shifted from syndromal, based on signs and symptoms, to a biomarker construct based on the pathological hallmarks of the disease: amyloid β deposition, pathologic tau, and neurodegeneration. Numerous genetic risk factors for sporadic AD have been identified, providing further insight into the molecular underpinnings of the disease. For the last two decades, however, drug development for AD has been proven to be particularly challenging. Here, we provide a unique overview of the drug development …


Artificial Intelligence And Neurology - Opportunities And Challenges In Pakistan, Adeel A. Memon, Junaid S. Kalia Dec 2021

Artificial Intelligence And Neurology - Opportunities And Challenges In Pakistan, Adeel A. Memon, Junaid S. Kalia

Pakistan Journal of Neurological Sciences (PJNS)

The field of artificial intelligence (AI) has undergone rapid development in neurological disorders over the past few decades. AI relies on large volumes of high-quality data. As a result, their use in low-resource settings has been limited due to the lack of a digitized health care system. This article will address the challenges and opportunities involved in implementing AI for neurological care in Pakistan, as well as discuss the types of digital health care data and the benefits of applying AI in resource-limited countries


The Constellation Of Centronuclear Myopathy And Craniofacial Dysmorphism, Mahnoor Hafeez Dec 2021

The Constellation Of Centronuclear Myopathy And Craniofacial Dysmorphism, Mahnoor Hafeez

Pakistan Journal of Neurological Sciences (PJNS)

ABSTRACT:

A 20 years old third-year MBBS female student from Dow Medical College in 2008 presented to the Neurology Dept. in Karachi with a short history of rapidly worsening bilateral lower limb weakness for 6 months. There was facial dysmorphism. Motor neuron disease was the suspicion; EMG/NCS study revealed non inflammatory myopathic process involving all limb muscles; Centro nuclear myopathy (CNM) was diagnosed via muscle biopsy. CNM is a group of congenital myopathies, where cell nuclei are abnormally located in skeletal muscle cells. Craniofacial dysmorphism is characterized by abnormal development of facial and skull structures. To the best of the …