Medicine and Health Sciences Commons^™

An Education Implementation Project In An Emergency Department To Increase Awareness And Referral For Trafficked Person Encounters, Stacey Lynn Alderman

Doctoral Dissertations and Projects

Human trafficking impacts sufferers on a global scale with serious and lifelong health issues associated with the illegal practice. Interventions for these victims’ extensive health issues must ignite healthcare staff education and expert clinical interventions. Due to these health problems, healthcare staff function on the front lines to identify and help trafficked persons. This study focused on the scope of trafficking and health staff awareness, identification strategies to help recognize trafficked persons, techniques for interviewing, best practice strategies for intervention and referral, and new coding guidelines. During the intervention, health staff received a human trafficking pre-education questionnaire, a research supported …

J Mich Dent Assoc Mar 2019

The Journal of the Michigan Dental Association

Archival issues of the Journal of the Michigan Dental Association may include reports on the activities of the association and its members, clinical articles, information on legal and ethical practice considerations, and perspectives of interest to MDA members and those in the oral health profession.

A Cleft Lip And Palate Gene, Irf6, Is Involved In Osteoblast Differentiation Of Craniofacial Bone, Jake Thompson, Fabian Mendoza, Ethan Tan, Jessica Wildgrube Bertol, Arju S. Gaggar, Goo Jun, Cláudia Cristina Biguetti, Walid Fakhouri

School of Podiatric Medicine Publications

Background:

Interferon Regulatory Factor 6 (IRF6) plays a critical role in embryonic tissue development including differentiation of epithelial cells. Besides orofacial clefting due to haploinsufficiency of IRF6, recent human genetic studies indicated that mutations in IRF6 are linked to small mandible and digit abnormalities. The function of IRF6 has been well studied in oral epithelium, however its role in craniofacial skeletal formation remains unknown. In this study, we investigated the role of Irf6 in craniofacial bone development using comparative analyses between wild-type and Irf6-null littermate mice

Results:

Immunostaining revealed the expression of IRF6 in hypertrophic chondrocytes, osteocytes …

Stable Between-Subject Statistical Inference From Unstable Within-Subject Functional Connectivity Estimates, Diego Vidaurre, Mark W. Woolrich, Anderson M. Winkler, Theodoros Karapanagiotidis, Jonathan Smallwood, Thomas E. Nichols

School of Medicine Publications

Spatial or temporal aspects of neural organization are known to be important indices of how cognition is organized. However, measurements and estimations are often noisy and many of the algorithms used are probabilistic, which in combination have been argued to limit studies exploring the neural basis of specific aspects of cognition. Focusing on static and dynamic functional connectivity estimations, we propose to leverage this variability to improve statistical efficiency in relating these estimations to behavior. To achieve this goal, we use a procedure based on permutation testing that provides a way of combining the results from many individual tests that …

Noise-Tolerant Modular Neural Network System For Classifying Ecg Signal, Alberto Ochoa, Luis J. Mena, Vanessa G. Felix, Apolinar Gonzalez, Walter Mena, Gladys E. Maestre

School of Medicine Publications

Millions of electrocardiograms (ECG) are interpreted every year, requiring specialized training for accurate interpretation. Because automated and accurate classification ECG signals will improve early diagnosis of heart condition, several neural network (NN) approaches have been proposed for classifying ECG signals. Current strategies for a critical step, the preprocessing for noise removal, are still unsatisfactory. We propose a modular NN approach based on artificial noise injection, to improve the generalization capability of the resulting model. The NN classifier initially performed a fairly accurate recognition of four types of cardiac anomalies in simulated ECG signals with minor, moderate, severe, and extreme noise, …

Features Of The Metabolic Syndrome In Late Adolescence Are Associated With Impaired Testicular Function At 20 Years Of Age, R. J. Hart, D. A. Doherty, T. A. Mori, L. A. Adams, R-C. Huang, N. Minaee, D. J. Handelsman, R. Mclachlan, R. J. Norman, J. E. Dickinson, J. K. Olynyk, L. J. Beilin

Research outputs 2014 to 2021

STUDY QUESTION: Are early signs of metabolic disorder in late adolescence associated with features of impaired testicular function many years before the majority seek parenthood?

SUMMARY ANSWER: Adolescents with features of metabolic disorder at 17 years, or insulin resistance (IR) at 20 years of age, show impaired testicular function and altered hormone levels compared to those without metabolic disorder.

WHAT IS KNOWN ALREADY: Controversial evidence suggests a recent decline in sperm production potentially linked to environmental influences, but its cause remains unclear. Concomitant increases in obesity and diabetes suggest that lifestyle factors may contribute to this decline in testicular function. …

The Impact Of Perceived Organisational Justice On Organisational Citizenship Behaviour In The Context Of Mergers, Fatima Ahmed Abdulla Al Nabhani

Dissertations

Scholars have relied on various approaches and methods to explain why organisations enter into a merger relationship, and how organisational initiatives impact employees' work outcomes. However, minimal attention has been directed towards the study of the relationship between Organisational Justice (OJ) and Organisational Citizenship Behaviour (OCB) in the post-merger period. The objective of this study was to examine how Organisational Justice affects Organisational Citizenship Behaviour in the context of mergers in the UAE. The study relied on a quantitative research method, social exchange mechanisms, and organisational justice theory to achieve the intended objectives. A total of 15 hypotheses were identified …

Genetic Architecture Of Human Obesity Traits In The Rhesus Macaque, Michael J. Raboin, John Letaw, Asia D. Mitchell, David Toffey, Jessica Mckelvey, Charles T. Roberts Jr, Joanne E. Curran, Amanda Vinson

School of Medicine Publications

Objective: Whereas the metabolic consequences of obesity have been studied extensively in the rhesus macaque, corollary genetic studies of obesity are nonexistent. This study assessed genetic contributions to spontaneous adiposity in this species.

Methods: Phenotypic variation by age class and sex for BMI, waist to height ratio, waist to thigh ratio, and waist circumference was assessed in 583 macaques. Total and sex-specific heritability for all traits was estimated, including waist to thigh ratio adjusted for BMI, as well as genotypic and phenotypic correlations. In addition, functional genetic variation at BDNF, FTO, LEP, LEPR, MC4R, PCSK1, POMC, and SIM1 was assessed …

Role Of The Hospital In The 21st Century Opioid Overdose Epidemic: The Addiction Medicine Consult Service, Kelsey C. Priest, Dennis Mccarty

OHSU-PSU School of Public Health Faculty Publications and Presentations

Objective: The aim of the study was to explore and describe the structure and design elements of addiction medicine consult (AMC) services within selected US hospitals. Methods: As part of a larger mixed methods study, 10 qualitative semi-structured telephone interviews were completed with board-certified addiction medicine physicians affiliated with the Addiction Medicine Foundation's Addiction Medicine Fellowship Programs at 9 US hospitals. Interviews were transcribed, coded, and analyzed using a directed content analysis. Results: Interviews completed with established AMC services in 9 hospitals probed AMC structure and design commonalities and differences across 4 domains: (1) availability and coverage, (2) team composition, …

The Santa Clara, 2019-02-28, Santa Clara University

The Santa Clara

No abstract provided.

Unintentional Bathtub Drowning Deaths Among Those Aged 65 Years And Older In Australia, Amy E. Peden, Richard C. Franklin, John H. Pearn M.D., Alison J. Mahony

International Journal of Aquatic Research and Education

When compared with other age groups, fatal drowning rates among seniors have stayed static. This study identifies causal factors in unintentional bathtub drowning deaths among people aged 65 years and over. This study is a 10-year (2003-2012) total population retrospective survey of all unintentional bathtub (baths, spa baths and showers) drowning deaths afflicting people aged 65 years and over. Data were sourced from the Australian National Coronial Information System. Risk factors and circumstantial variables were analysed including sex, age, activity prior to drowning, alcohol, drugs, pre-existing medical conditions, living circumstances, time until found, and performance of cardio-pulmonary resuscitation (CPR). There …

Improving The Quality Of Patient-Provider Interactions And Promoting Equitable, Accessible And Patient-Centered Cancer Care, C. Vaughan-Briggs, Lcsw, A. Petok, Lcsw, Mph, T. Dejesse, Amy Leader, Drph, Mph

Department of Medical Oncology Posters

• Philadelphia is among the top 10 cities in the US with populations over 500,000 with a high Community Need Index score (CNI- severity of Health disparity)
• Data from 2015 County Health Ranking, had Philadelphia last of all 67 counties in the state for social economic factors. (unemployment, income inequality, injury deaths, etc. )
• Cancer is a leading cause of mortality in the US
• The SKCC participated in a year-long, externally supported self study to improve the quality of patientprovider interactions and promote more equitable, accessible and patient- centered cancer care. This program aligned with internal initiatives.
• SKCC at Jefferson is …

Testing For Subclinical Hyperthyroidism On Diagnosis Of Osteoporosis Or Fracture, Amanda Reber

Nursing Capstones

No abstract provided.

Ablation Of Both Cx40 And Panx1 Results In Similar Cardiovascular Phenotypes Exhibited In Cx40 Knockout Mice, Nicole M. Novielli-Kuntz, Meghan L. Jelen, Kevin Barr, Leon J. Delalio, Qingping Feng, Brant E. Isakson, Robert Gros, Dale Laird

Anatomy and Cell Biology Publications

Connexins (Cxs) and pannexins (Panxs) are highly regulated large-pore channel-forming proteins that participate in cellular communication via small molecular exchange with the extracellular microenvironment, or in the case of connexins, directly between cells. Given the putative functional overlap between single membrane-spanning connexin hemichannels and Panx channels, and cardiovascular system prevalence, we generated the first Cx40(-/-)Panx1(-/-) mouse with the anticipation that this genetic modification would lead to a severe cardiovascular phenotype. Mice null for both Cx40 and Panx1 produced litter sizes and adult growth progression similar to wild-type (WT), Cx40(-/-) and Panx1(-/-) mice. Akin to Cx40(-/-) mice, Cx40(-/-) Panx1(-/-) mice exhibited …

Novel Flexible Heteroarotinoid, Sl-1-39, Inhibits Her2-Positive Breast Cancer Cell Proliferation By Promoting Lysosomal Degradation Of Her2., Hongye Zou, Mary B. Sevigny, Shengquan Liu, David T. Madden, Maggie Louie

Natural Sciences and Mathematics | Faculty Scholarship

SL-1-39 [1-(4-chloro-3-methylphenyl)-3-(4-nitrophenyl)thiourea] is a new flexible heteroarotinoid (Flex-Het) analog derived from the parental compound, SHetA2, previously shown to inhibit cell growth across multiple cancer types. The current study aims to determine growth inhibitory effects of SL-1-39 across the different subtypes of breast cancer cells and delineate its molecular mechanism. Our results demonstrate that while SL-1-39 blocks cell proliferation of all breast cancer subtypes tested, it has the highest efficacy against HER2+ breast cancer cells. Molecular analyses suggest that SL-1-39 prevents S phase progression of HER2+ breast cancer cells (SKBR3 and MDA-MB-453), which is consistent with reduced expression of key cell-cycle …

Pretreatment With A Heat-Killed Probiotic Modulates The Nlrp3 Inflammasome And Attenuates Colitis-Associated Colorectal Cancer In Mice., I-Che Chung, Chun-Nan Ouyang, Sheng-Ning Yuan, Hsin-Chung Lin, Kuo-Yang Huang, Pao-Shu Wu, Chia-Yuan Liu, Kuen-Jou Tsai, Lai-Keng Loi, Yu-Jen Chen, An-Ko Chung, David M. Ojcius, Yu-Sun Chang, Lih-Chyang Chen

All Dugoni School of Dentistry Faculty Articles

Colorectal cancer (CRC) is one of the most common malignancies worldwide. Inflammation contributes to cancer development and inflammatory bowel disease is an important risk factor for CRC. The aim of this study is to assess whether a widely used probiotic Enterococcus faecalis can modulate the NLRP3 inflammasome and protect against colitis and colitis-associated CRC. We studied the effect of heat-killed cells of E. faecalis on NLRP3 inflammasome activation in THP-1-derived macrophages. Pretreatment of E. faecalis or NLRP3 siRNA can inhibit NLRP3 inflammasome activation in macrophages in response to fecal content or commensal microbes, P. mirabilis or E. coli, according …

Perception Of People Living With Hiv/Aids On Social Stigma Of Hiv/Aids In Sukoharjo District, Titik Haryanti, Wartini Wartini

Kesmas

The stigma of wrong society about HIV / AIDS is one of the obstacles to prevention and control of HIV / AIDS in Sukoharjo District. This study aims to determine the relationship of characteristics, causal factors and duration of HIV / AIDS with the perception of people living with HIV to the stigma of society about HIV / AIDS in Sukoharjo District. The research used is analytical descriptive with cross sectional approach. The population is all people with HIV / AIDS until April 2016 amounted to 256 with a sample of 156 people with sampling technique quota sampling. Bivariate analysis …

Prediction Models For Descreasing Visual Acuity In Wig Makers, Nur Ulfah, Siti Harwanti, Ngadiman Ngadiman

Kesmas

One of the occupational diseases that can arise for workers with high accuracy is a decrease in their visual acuity. Therefore, it is necessary to study the risk factors of decreasing visual acuity in workers with high accuracy, such as in wig makers. This study aimed to examine the correlation between age, working period, lighting intensity, fatigue, and nutritional status with visual acuity, and to observe the main risk factors that can be used as a reference for predicting decreasing visual acuity. This study was an observational study that used a cross-sectional design. The population number for this study was …

Ectopic Pituitary Adenoma Presenting As A Clival Mass., Juan J Altafulla, Joshua Prickett, Graham Dupont, R Shane Tubbs, Zachary Litvack

Articles, Abstracts, and Reports

Pituitary adenomas are well described in the literature and are frequently observed and treated in clinical practice by neurosurgeons. On the other hand, ectopic adenomas are a diagnostic enigma; a good understanding of anatomy and radiological characteristics is crucial for the successful management of such pathologies. In this paper, we describe the case of a 77-year-old woman who presented with a clival mass invading the left cavernous sinus; we also discuss the associated diagnostic techniques, approaches, imaging options, and characteristics.

Full Issue, Volume 7, Number 1, Donna J. Peterson, Rich Poling

Journal of Human Sciences and Extension

No abstract provided.

Ultrasound-Triggered Antibiotic Release From Peek Clips To Prevent Spinal Fusion Infection: Initial Evaluations., Lauren J. Delaney, Daniel Macdonald, Jay Leung, Keith Fitzgerald, Alex M. Sevit, John R. Eisenbrey, Neil Patel, Flemming Forsberg, Christopher K. Kepler, Taolin Fang, Steven M. Kurtz, Noreen J. Hickok

Department of Orthopaedic Surgery Faculty Papers

Despite aggressive peri-operative antibiotic treatments, up to 10% of patients undergoing instrumented spinal surgery develop an infection. Like most implant-associated infections, spinal infections persist through colonization and biofilm formation on spinal instrumentation, which can include metal screws and rods for fixation and an intervertebral cage commonly comprised of polyether ether ketone (PEEK). We have designed a PEEK antibiotic reservoir that would clip to the metal fixation rod and that would achieve slow antibiotic release over several days, followed by a bolus release of antibiotics triggered by ultrasound (US) rupture of a reservoir membrane. We have found using human physiological fluid …

Dermoid Cyst With No Intracranial Extension: A Case Report And Literature Review, Asra Tanwir, Noor Malik, Gohar Javed, Romana Idress

Section of Neurosurgery

Background: Dermoid cysts are cystic inclusion tumors. They comprise hair follicles, sweat glands, and sebaceous glands. They have lining of stratified squamous epithelium. The most common areas involved are face, lower back, and ovaries. Congenital cystic dermoid involving the anterior fontanelle with no intracranial extension is a rare scalp swelling. We present a case of dermoid cyst with no intracranial extension.
Case description: We report a case of 4-month-old child presented with a history of a scalp swelling since birth. The swelling increased in size progressively. Magnetic resonance imaging of the brain revealed extracranial cystic lesion over anterior fontanelle with …

Analisa Pengelolaan Kebutuhan Logistik Farmasi Pada Instalasi Farmasi Rs Mbsd Periode Juli 2017- Juni 2018analisa Pengelolaan Kebutuhan Logistik Farmasi Pada Instalasi Farmasi Rs Mbsd Periode Juli 2017- Juni 2018analisa Pengelolaan Kebutuhan Logistik Farmasi Pada Instalasi Farmasi Rs Mbsd Periode Juli 2017- Juni 2018, Suherman Suherman, Atik Nurwahyuni

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

There is still a vacuum in the availability of medicines on a monthly basis, raising questions about how to manage pharmaceutical logistics in MBSD Hospital Pharmacy Installation. The purpose of this research is to find out how the logistics management system of drug supplies and various problems that occur at each stage of implementation in the MBSD Hospital Pharmacy Installation. This research uses descriptive and analytical methods that are quantitative and qualitative by conducting in-depth interviews, document review, and calculation of ABC drug classifications to then calculate the Economic Order Quantity value and Re Order Point time on drugs classified …

Kajian Kebutuhan Pengembangan Rumah Sakit Pemerintah Daerah Kelas B Di Provinsi Sulawesi Utara, Puput Oktamianti

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

The existence of regulations regarding regional referrals established by the central government, encourages the North Sulawesi regional government to provide regional referral hospitals that have service capabilities as class B hospitals. For the development of North Sulawesi Provincial Hospital in the future, basic information on services, facilities, facilities and infrastructure, as well as market coverage that depends on system governance, HR capabilities, physical buildings and equipment and resources. The purpose of this study is to examine the service needs of North Sulawesi Provincial Hospital which includes demographic studies, socio-economic studies, studies of morbidity and mortality, study of policies and regulations, …

Penerapan Metode Abc Indeks Kritis Dalam Pengelolaan Persediaan Obat Di Instalasi Farmasi Rumah Sakit Xyz Pekanbaru, Riau Tahun 2018, Monika Noviera Susanto, Vetty Yulianty Permanasari

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

The process of making the XYZ Hospital formulary by the Therapy Pharmacy Team (TFT) has not considered the critical level of a medicine for patients. The failure to carry out the assessment has caused an unplanned purchase of the medicine that needed immediately and affecting patient safety. The ABC method can identify drugs that must always be available and worth a large investment. There is no cost control of drug supplies at XYZ Hospital because data on the value of investment in drugs have not been analyzed. This study uses a qualitative research design by applying the ABC index critical …

Implementasi Green Hospital Di Rsud R. Syamsudin, Sh Dengan Kriteria Kerangka Kinerja Ekselen Malcolm Baldrige, Haniah Alatas, Dumilah Ayuningtyas

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

The existence of green hospital is very necessary to overcome climate change which can cause disruption to human health and the environment, because hospitals are one of the contributors to pollution. RSUD R. Syamsudin, SH became a member of the Global Green and Healthy Hospital and is committed to implementing ten agendas, namely leadership, chemicals, waste, energy, water, transportation, food, pharmacy, buildings, and purchasing. Aim of this study is to analyze the implementation of green hospital with the Malcolm Baldrige Criteria Framework for Excellence Performance. Malcolm Baldrige Criteria evaluates based on seven criteria which isleadership, strategy, customer, measurement, analysis, and …

Srategi Bauran Pemasaran Pelayanan Kesehatan Rsd Kol. Abundjani Bangko Di Era Jaminan Kesehatan Nasional (Jkn), Arismen Arismen, Wahyu Sulistiadi, Amal Chalik Sjaaf

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

The policy developed by the government in the form of a National Health Insurance (JKN) program whose funding is managed by the BPJS, must be supported by all health service facilities both government and private. RSD Kol. Abundjani Bangko is a regional hospital belonging to the Merangin District Government that has collaborated with BPJS to serve BPJS participants in the health services sector in 2014. In the course of the increase there have been an increase in the number of BPJS participants who have been referred and treated to RSD Kol. Abundjani Bangko. The increase in patient visits on the …

Srategi Pemasaran Rsud Prof. Dr. H.M. Chatib Quzwain Sarolangun Jambi Tahun 2018, Ahmad Bajri, Wahyu Sulistiadi

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

Undang-Undang No.36/2009 Pasal 34 Ayat 2 states that the community has the right to obtain health protection from the state. In order to regulate comprehensive health protection for the community, the government requires all hospitals, both government and private hospitals to take part in the National Health Insurance / JKN Program. In this regard, the General Hospital of Prof. Dr. H.M. Chatib Quzwain is a class C regional hospital that has only been operating since 2008, so there are still many shortcomings and limitations, especially in the field of services and supporting facilities. Knowing this, efforts have been made to …

Strategi Peningkatan Mutu Dan Keselamatan Pasien Di Rumah Sakit Umum Daerah Kepulauan Seribu Tahun 2019 – 2023, Agus Ariyanto Haryoso, Dumilah Ayuningtyas

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

Quality of service and patient savety now adays has become the main demand of hospital customer, even now, become one of evaluation point in hospital accreditation. Nevertheless, quality and patient savety in Kepulauan Seribu Public Hospital (RSUD Kepulauan Seribu) has not been accredited yet. RSUD Kepulauan Seribu plans to increase quality and patient savety so that can go through accreditation. This thesis aims to arrange strategies of Quality improvement and Patient Savety in Years 2019- 2023. The study in this thesis is qualitative. The study digs informations from informans to obtain internal and external factors hich used to arrange strategies. …

Influence Of Decentralization And Type Of Patient On Loss To Follow-Up Among Multidrug-Resistant Tuberculosis Patients In Indonesia From 2014 To 2015, Noerfitri Noerfitri, R. Sutiawan, Tri Yunis Miko Wahyono, Pratiwi Ayuningtyas Hartono

Kesmas

Drug-resistant tuberculosis (TB) patients have a greater risk of loss to follow-up (LTFU) than drug-sensitive TB patients, due to their longer treatment duration. This study aimed to determine the influence of decentralization and patient type on LTFU among multidrug-resistant TB (MDR-TB) patients in Indonesia. A retrospective cohort study was conducted at all MDR-TB treatment healthcare facilities in Indonesia from 014 to 2015. Using total sampling technique, 961 patients were examined and sampled. Of these patients, 86.03% were decentralized. Patients were classified into types as follows: 35.17% were “relapse” patients, 5.52% were “new,” 13.94% were classified as “after LTFU” patients, 23.10% …