Medicine and Health Sciences Commons^™

Monitoring Progression Of Ductal Carcinoma In Situ Using Photoacoustics And Contrast-Enhanced Ultrasound., Ryan Margolis, Corinne Wessner, Maria Stanczak, Ji-Bin Liu, Jingzhi Li, Kibo Nam, Flemming Forsberg, John R. Eisenbrey

Department of Radiology Faculty Papers

Breast cancer is the leading form of cancer in women, accounting for approximately 41,400 deaths in 2018. While a variety of risk factors have been identified, physical exercise has been linked to reducing both the risk and aggressiveness of breast cancer. Within breast cancer, ductal carcinoma in situ (DCIS) is a common finding. However, less than 25% of DCIS tumors actually progress into invasive breast cancer, resulting in overtreatment. This overtreatment is due to a lack of predictive precursors to assess aggressiveness and development of DCIS. We hypothesize that tissue oxygenation and perfusion measured by photoacoustic and contrast-enhanced ultrasound imaging, …

Ecological Interventions To Prevent And Manage Zoonotic Pathogen Spillover, Susanne H. Sokolow, Nicole Nova, Kim M. Pepin, Alison J. Peel, Juliet R.C. Pulliam, Kezia Manlove, Paul C. Cross, Daniel J. Becker, Raina K. Plowright, Hamish Mccallum, Giulio A. De Leo

United States Department of Agriculture Wildlife Services: Staff Publications

Spillover of a pathogen from awildlife reservoir into a human or livestock host requires the pathogen to overcome a hierarchical series of barriers. Interventions aimed at one or more of these barriers may be able to prevent the occurrence of spillover. Here, we demonstrate how interventions that target the ecological context in which spillover occurs (i.e. ecological interventions) can complement conventional approaches like vaccination, treatment, disinfection and chemical control. Accelerating spillover owing to environmental change requires effective, affordable, durable and scalable solutions that fully harness the complex processes involved in cross-species pathogen spillover.

This article is part of the theme …

Week Of May 20, 2019, New York Medical College

InTouch

• Employees Celebrated for Years of Service
• Convocation of Thanks Offers Closure to Students and Families of Donors
• Looking Back: The History of New York Medical College
• NYMC Celebrates Jewish American Heritage Month
• Grand Opening is Set for the Café

Prescription Opioid Use Patterns, Use Disorder Diagnoses, And Addiction Treatment Receipt After The 2014 Medicaid Expansion In Oregon, Rachel Springer, Miguel Marino, Steffani R. Bailey, Heather Angier, Jean O'Malley, Megan Hoopes, Stephan Lindner, Jennifer E. Devoe, Nathalie Huguet

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background/Aims: Evidence suggests Medicaid beneficiaries in the USA are prescribed opioids more frequently than are people who are privately‐insured, but little is known about opioid prescribing patterns among Medicaid enrollees who gained coverage via the Affordable Care Act Medicaid expansions. This study compared the prevalence of receipt of opioid prescriptions and opioid‐use‐disorder (OUD), along with time from OUD diagnosis to medication‐assisted treatment (MAT) receipt between Oregon residents who had been continuously insured by Medicaid, were newly insured after Medicaid expansion in 2014, or returned to Medicaid coverage after expansion.

Design: Cross‐sectional study using inverse‐propensity weights to adjust for …

Scavenging In The Anthropocene: Human Impact Drives Vertebrate Scavenger Species Richness At A Global Scale, Esther Sebastián‐González, Jomar Magalhães Barbosa, Juan M. Pérez‐García, Zebensui Morales‐Reyes, Francisco Botella, Pedro P. Olea, Patricia Mateo‐Tomás, Marcos Moleón, Fernando Hiraldo, Eneko Arrondo, José A. Donázar, Ainara Cortés‐Avizanda, Nuria Selva, Sergio A. Lambertucci, Aishwarya Bhattacharjee, Alexis Brewer, Erin Abernethy, Olin E. Rhodes Jr., Kelsey Turner, James C. Beasley, Travis L. Devault, Andrés Ordiz, Camilla Wikenros, Barbara Zimmermann, Petter Wabakken, Christopher C. Wilmers, Justine A. Smith, Corinne J. Kendall, Darcy Ogada, Evan R. Buechley, Ethan Frehner, Maximilian L. Allen, Heiko U. Wittmer, James R.A. Butler, Johan T. Du Toit, John Read, David Wilson, Klemen Jerina, Miha Krofel, Rich Kostecke, Richard Inger, Arockianathan Samson, Lara Naves‐Alegre, José A. Sánchez‐Zapata

United States Department of Agriculture Wildlife Services: Staff Publications

Understanding the distribution of biodiversity across the Earth is one of the most challenging questions in biology. Much research has been directed at explaining the species latitudinal pattern showing that communities are richer in tropical areas; however, despite decades of research, a general consensus has not yet emerged. In addition, global biodiversity patterns are being rapidly altered by human activities. Here, we aim to describe large‐scale patterns of species richness and diversity in terrestrial vertebrate scavenger (carrion‐consuming) assemblages, which provide key ecosystem functions and services. We used a worldwide dataset comprising 43 sites, where vertebrate scavenger assemblages were identified using …

Radiation Induced Symptomatic Critical Left Main Lesion And Symptomatic Aortic Stenosis In An Inoperable Candidate: Role Of Percutaneous Intervention, Fnu Vikram Md, Ghulam Akbar Md, Mohammed Ameen Md, Roshni N. Patel, Lohit Garg Md, Deborah W. Sundlof Do, Nainesh C. Patel Md

Department of Medicine

No abstract provided.

Exploring The Decisions Involved In Evidence-Based Practice Adoption By Athletic Trainers, Brittany Vorndran Allard

Seton Hall University Dissertations and Theses (ETDs)

Background: The governing bodies of athletic training have been putting an emphasis on evidence-based practice (EBP) through college curriculum changes and continuing education requirements. Research has shown these interventions are increasing knowledge, but there is still a knowledge to practice gap.

Purpose: The purpose of this study was to explore the decisions involved in EBP adoption by practicing athletic trainers (ATs).

Methods: This study utilized a general qualitative approach that was exploratory in nature. Fifteen participants participated in the study, and all were practicing certified athletic trainers who stated they were using EBP when making treatment decisions.

Data Collection …

Use Of A Whole-Cell Elisa To Detect Additional Antibodies In Setting Of Suspected Heparin-Induced Thrombocytopenia, Eva M. Bashover, Catherine M. Stefaniuk, Clifford V. Harding, Robert W. Maitta

Faculty Scholarship

OBJECTIVES: Type II heparin-induced thrombocytopenia (HIT) is mediated by formation of antibodies to platelet factor 4 (PF4)-heparin complexes. We evaluated anti-PF4-heparin-negative samples for the presence of additional anti-platelet and anti-red blood cell (RBC) antibodies using whole-cell platelet/ RBC ELISAs we developed. METHODS: Seventy-three samples tested for anti-PF4-heparin by ELISA were included: 62 tested negative, 9 tested positive, and 2 had equivocal results. Plasma specimens from healthy donors were used as controls. RESULTS: 100% (9/9) anti-PF4-positive samples had anti-platelet antibodies detected by whole-cell platelet ELISA. 42.2% (27/64) anti-PF4-heparin-negative samples were negative for anti-platelet and anti-RBC antibodies. 32.8% (21/64) negative samples showed …

Medical School Watercooler Newsletter - May 19, 2019, Lindsey Lyle

Watercooler Newsletter

This is the May 19, 2019 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

Nominate outstanding colleagues for Employee of the Month

USA Health welcomes neuroradiologist Gregg Delgado, D.O.

The Economic Impacts Of Blackbird (Icteridae) Damage To Sunflower In The Usa, Karina Ernst, Julie Elser, George Linz, Hans Kandel, Jason Holderieath, Samantha Degroot, Steven Shwiff, Stephanie Shwiff

United States Department of Agriculture Wildlife Services: Staff Publications

BACKGROUND: Blackbird (Icteridae) damage to ripening sunflower (Helianthus annuus L.) has been a persistent economic issue in the USA for the last five decades. To quantify losses, we surveyed blackbird damage from 2001 to 2013 (excluding 2004) to physiologically mature sunflower in eight states: North Dakota, South Dakota, Texas, Nebraska, Minnesota, Colorado, Kansas, and Vermont.

RESULTS:We pooled data gathered during the most recent 5 years (2009 to 2013) of the survey and found losses averaged $US2.5 million and $US11.3 million for confectionery and oilseed hybrids, respectively. Three states, North Dakota, South Dakota, and Nebraska, had sufficient acreage and bird damage …

A Method Paper For Earplug-Fitting Augmentative Procedures Tested In Groups Of More Experienced And Less Experienced Users Of Hearing Protection, Natalie Dixon, Antony Joseph

AuD Capstone Projects - Communication Sciences and Disorders

Although a long history of research has led to extensive knowledge about hearing protection devices (HPDs), there has been limited research about procedures that provide aid and verification during HPD insertion, although several studies have reported about HPD training. No standard methods have been established for training of earplug use (Takahashi, 2011).

A review of the literature revealed a need for tools that might be used to improve user ability to properly insert HPDs consistently, even in the absence of training, because training is rarely provided in the workplace. The prevailing research question was "Does the use of simple fitting …

Reversal Of P-Glycoprotein And Breast Cancer Resistance Protein Mediated Multidrug Resistance In Vitro Using In Silico Identified Novel Compounds, Amila Nanayakkara

Biological Sciences Theses and Dissertations

Multidrug resistance (MDR) is a major cause of chemotherapy failure. Overexpression of ATP-binding cassette (ABC) transporters, P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) are two well-studied drug transporters which are associated with MDR. These two transporters also act as a major functional unit of the blood brain barrier to protect the brain from xenobiotics and toxins. Lack of clinically approved P-gp and BCRP inhibitors renders chemotherapy treatments of many MDR cancers ineffective and obstructs drug uptake into the brain.

Using computational methods, we have identified new compounds that inhibit P-gp (Brewer et al., Mol. Pharmacol. 2014). Several of …

Impact Of Tumor Regional Involvement On Active Surveillance Outcomes: Validation Of The Cumulative Cancer Location Metric In A Us Population., Joon Yau Leong, Courtney Capella, Seth Teplitsky, Leonard G. Gomella, Edouard J. Trabulsi, Costas D. Lallas, Thenappan Chandrasekar

Department of Urology Faculty Papers

BACKGROUND: Treatment progression for men on active surveillance (AS) for prostate cancer (PCa) is driven primarily by grade and volume progression on isolated prostate biopsies (PBx). As PCa is a multifocal disease, regional disease progression over time should be accounted for.

OBJECTIVE: To validate the utility of the cumulative cancer location (CCLO) metric, which assesses regional core involvement, as described by Erickson et al (Cumulative cancer locations is a novel metric for predicting active surveillance outcomes: a multicenter study. Eur Urol Oncol 2018;1:268-75), in predicting AS outcomes in a North American cohort.

DESIGN, SETTING, AND PARTICIPANTS: A single-institutional retrospective chart …

Promoting Resilience In Economically Disadvantaged Adolescents Through School-Based Expressive Arts Groups, Bailey Knox

Expressive Therapies Capstone Theses

Since 2013, the majority of students served by the public school system in the United States have been considered “low-income” by the federal government. The stressors associated with low socioeconomic status significantly increase risk for social, emotional and behavioral challenges at all age levels, but can be particularly damaging to adolescents coping with heightened stress levels related to the intense multi-dimensional changes that define this developmental period. As the correlation between economic disadvantage and negative socio-emotional and academic outcomes is increasingly evidenced, schools have begun to recognize their responsibility for providing preventative mental health care to high-risk students. Over the …

A Literature Review Of Nature-Based Expressive Arts Therapy For Bereaved Children, Wendy Dalton

Expressive Therapies Capstone Theses

There is a need for increased visibility of child bereavement to expand research in and accessibility of developmentally appropriate supports, which views the child holistically and within their biopsychosocial context. Worden’s (1996) formative work with child bereavement resulting in the "tasks" of child bereavement was the first and most recent study of its scale and kind. This marked an affirming of grief as normative response to death and occurring throughout the developmental lifespan. This work also highlights the need for additional inquiry to expand and deepen understanding of child bereavement. A growing body of research suggests that ecotherapy and expressive …

Music Therapy Assisted Childbirth In The United States: A Critical Literature Review, Sydney Mohr

Expressive Therapies Capstone Theses

Music therapy assisted childbirth is an approach of music therapy in which a licensed and credentialed professional utilizes music therapy interventions to address a variety of goals during childbirth. There is a lack of literature and missing knowledge on the topic, associated with an increased rate in traumatic birth cases, mothers with post-traumatic stress disorder, and postpartum anxiety and depression. The literature review provides a summary of the historical context of feminist theory and feminism, as well as brief descriptions of music therapy, guided imagery and music, and familiar music interventions. One of the primary goals of this type of …

Dance/Movement Therapy As A Tool To Improve Social Skills In Children And Adolescents With Autism Spectrum Disorder: A Literature Review, Holly Berlandy

Expressive Therapies Capstone Theses

Abstract

Autism spectrum disorder is a neurodevelopmental disorder diagnosed by the presence of social communication and interaction deficits present in their day to day. The deficits present in this disorder appear within the first three years of life and lead to problems with connecting and interacting with other individuals including their own family members. As a result, children and adolescents with Autism spectrum disorder often experience negative self-image and lack the proper skills to interact with others. Autism spectrum disorder is becoming more commonly diagnosed and yet there remains a gap in interventions and treatment due to the individualized appearance …

Moving Blind Spots: Cultural Bias In The Movement Repertoire Of Dance/Movement Therapists, Ebony Nichols

Expressive Therapies Capstone Theses

This thesis explores the need for cultural diversity in the field of dance/movement therapy and the impact of unconscious bias as it relates to cultural rhythmic patterns, movement styles, and music choices in therapeutic practice. This literature review examines the historical context that has contributed to the field of dance/movement therapy while outlining cultural competency and ethical considerations in practice as it relates to cultural and/or race identity. Common themes are summarized notating the effects of oppression, bias, and trauma on populations of statistically marginalized communities with specific emphases on African American cultural identity. With consideration toward action steps, culturally …

Breathing Life Into Life: A Literature Review Supporting Body-Based Interventions In The Treatment Of Trauma, Andrea Werbalowksy

Expressive Therapies Capstone Theses

In the recent turn toward a more trauma-informed practice of mental health counseling, a glaring gap remains between the research validating that trauma is a somatic experience and the continued privileging of cognitive and behaviorist interventions commonly used to treat trauma. In an effort to explore this gap, this paper presents a literature review inquiry into the neurophysiological and overall life effects trauma can have on the people who experience it. The review further explores how Stephen Porges’s Polyvagal Theory elucidates the benefits of using body-based therapeutic interventions in the treatment of trauma. The inquiry investigates the wide gap between …

The Study Of Neurological Response In Art Therapy And Trauma: A Literature Review, Kristin Weber

Expressive Therapies Capstone Theses

This review will focus on neurological research and art therapy practice to consider benefits of the integration of science and the creative therapies. These topics will be addressed through a trauma informed theoretical lens, focusing on Post-Traumatic Stress Disorder and Traumatic Brain Injury diagnoses in the US military veteran population. Arts-based, qualitative, and quantitative research were correlated within this review to discover links between neurology and art therapy’s unique impact on trauma, and the outcome of combining these practices. The conclusions found that, with limited research connecting these two fields, there is a possibility for enhanced trauma treatment through the …

Beyond Regression: An Investigation Of Art Material Choice For Children With Trauma, Natalie Lane

Expressive Therapies Capstone Theses

Choice in art materials and the artistic process are arguably two of the primary facets of how art making can be therapeutic. The purpose of the present inquiry was to investigate the impacts of art material choice in children who have experienced trauma. Using the expressive therapies continuum (ETC) as a foundation for choosing art materials in a therapeutic context, this inquiry sought to introduce art materials in the kinesthetic/sensory component of the ETC (e.g., clay, paint, large paint brushes, etc.). As a mediating consideration, this inquiry articulated the responsibilities and obligations that the art therapist possesses in working with …

“There Was Something Magical About This Group”: Building Cohesion In A Psychiatric Hospital, Mariah L. Logan

Expressive Therapies Capstone Theses

This capstone details the development and implementation of Hope Notes, an expressive arts therapy intervention used in a private psychiatric hospital setting. Hope Notes was carried out in the group setting with adolescent and adult clients in a partial-hospitalization or inpatient hospitalization with a range of diagnoses and symptoms including, but not limited to, depression, anxiety, bipolar disorder, schizophrenia, trauma disorders including post-traumatic stress, and obsessive-compulsive disorder with symptoms of delusions, hallucinations, suicidality and homicidally. Using expressive arts therapy the clients worked together to collaboratively discuss, create, design, and build an art piece intended to increase group cohesion and connection …

Digital Music Making: Developing A Method For Using Technology In Music Psychotherapy, Sangeetha Kavety

Expressive Therapies Capstone Theses

The use of technology, specifically digital songwriting and music making, in the context of psychotherapy is a subject that is not yet as well researched or practiced in the field of music therapy. The majority of the existing literature acknowledges the assistive function that technology such as tablets, smartphones, and computers can play in treatment of populations with cognitive and motor difficulties. However, there is little regarding the use of technology as the main means of creating music, and even less in the context of treatment of psychiatric disorders in children and adolescents in family settings. For this capstone project, …

Considering Art Therapy For Adults With Fear Of Cancer Recurrence (Fcr): A Literature Review, Max Roberts

Expressive Therapies Capstone Theses

Fear of cancer recurrence (FCR) is a major problem for many cancer survivors. As cancer treatments improve and more people are surviving cancer, FCR will likely become a larger problem in general for the healthcare system. Art therapists working with cancer survivors need to be prepared for addressing FCR as they are likely to encounter this clinical issue. A literature search was conducted and no research investigating art therapy specifically for FCR was found, indicating there is currently no empirically supported approach to art therapy for FCR. Mindfulness and acceptance-based therapies appear to be efficacious for reducing effects of FCR. …

Exploring The Usage Of Found Objects In Art Therapy For Bereavement: A Literature Review, Bridget Bogan

Expressive Therapies Capstone Theses

Bereavement is a multifaceted, evolving, and intensely individual experience. Moving away from a linear theoretical framework towards a constructivist theoretical model promotes the healing properties of self-narrative while incorporating the story of the loss of a loved one. Most important to bereaved individuals, as indicated by current research on the topics of death, grief, and bereavement are memory keeping, meaning making, and continued bonds with the deceased. These common themes have remained consistent since the Victorian age.

Traditional mourning jewelry represents a form of memorialization and continued bonds with the dead. Alternative forms of art using found objects belonging to …

Integrating Digital App Technologies Within Traditional Expressive Arts Therapy For Children And Adolescents, Sarah Storjohann

Expressive Therapies Capstone Theses

In recent years, technology in the form of digital applications (apps) has emerged as a fundamental aspect of everyday life as well as a practical, convenient, and inexpensive tool for artistic self-expression, most notably amongst children and adolescents. Ninety-eight percent of U.S. households currently possess some form of mobile device (Rideout, 2017), with an estimated 95% of U.S. teenagers ages 13 to 17 owning a Smartphone (Anderson & Jiang, 2018). As digital natives, children and adolescents are more likely to identify with and connect to these arts-based methods. Clinician perspective concerning digital integration varies across a wide spectrum. Through a …

Expressive Mindfulness: A Trauma-Sensitive Expressive Arts Therapy Group Method, Meghan Daly

Expressive Therapies Capstone Theses

Mindfulness and expressive arts therapy are both supportive of directing attention in a manner that promotes integration and function of a person. In this paper, a trauma-sensitive method was created for use in a day treatment setting for adults with severe and persistent mental illness (SPMI). This method utilized expressive movement, visual art making with three different materials, and creative writing to encourage mindful, non-judgmental acceptance of the present moment; a sense of relaxation; and an overall increase in quality of life. During development of the method arts-based research informed the choice of materials, music, and structure of the group. …

Patterned Sensory Enhancement-Based Interventions In An Acute Rehabilitation Setting: Development Of A Method, Lionel Cheong

Expressive Therapies Capstone Theses

Constraint-induced therapy (CIT) or Constraint-induced movement therapy (CIMT) is used in rehabilitation to improve upper extremity function in patients who suffer from brain injuries, such as stroke or cerebral palsy. By engaging in repetitive exercises and increasing the use of the affect area of the upper extremity, the brain develops a change in neural pathways that helps recover the use of limbs by these patients. Unfortunately, one of the main limitations of CIT is the low compliance with patients involved in CIT, due to the stopping of use of compensation strategies, and the intensity and duration of the treatment, especially …

A Laughing Matter: Transforming Trauma Through Therapeutic Humor And Expressive Arts Therapy, Alison M. Landoni

Expressive Therapies Capstone Theses

Humor and trauma share two characteristics: they are both perspectival in nature and hold incongruity at their core, however, their impacts are profoundly different for the perceiver. As humor and laughter open one’s psyche and invite positive social exchanges, trauma produces more dissociative, dysregulated and dysfunctional interactions. While fundamental to interpersonal experiences, there has been limited research about the use of humor and laughter as essential tools within the mental health therapeutic alliance. Neurological research and case studies have shown that humor and laughter can have hormonal, physiological and psychological benefits. Due to the perspectival nature of humor and trauma, …

A Literature Review On Substance Related Grief And Expressive Art Therapy Support Groups, Holly N. St. Cyr

Expressive Therapies Capstone Theses

In the year of 2017, 18.7 million Americans aged 18 years or older were reported to have a substance use disorder and the pervasiveness of substance related deaths escalated (McCance- Katz, 2017). Researchers have examined how grief experienced by substance users and their loved ones is often disenfranchised by social stigmatization, loss of support, and feelings of regret, blame, humiliation, and shame. According to Valentine, Bauld, and Walter, (2016) “bereavement following a drug or alcohol related death has been largely neglected in research and service provision, despite its global prevalence and potentially devastating consequences for those concerned,” (p. 283). Studies …