Medicine and Health Sciences Commons^™

Utilization Of Palliative Care To Reduce 30 Day Readmission In Heart Failure Patients, Esmeralda Concepcion, Ofelia Udarbe, Nancy Hart

All Nursing Boot Camp Posters

No abstract provided.

Implementing A Discharge Tool To Decrease The Length Of Stay In The Observation Unit, Mafe Chase, Tyson Hallock

All Nursing Boot Camp Posters

No abstract provided.

College Of Health Sciences E-Newsletter, Summer 2019, Irvin B. Harrell (Editor)

Ellmer College of Health Sciences Newsletters

Summer 2019 issue of Old Dominion University's College of Health Sciences Newsletter.

Pulmonary Alveolar Microlithiasis Diagnosed With Radiography, Ct, And Bone Scintigraphy, Emad Alkankan, Hasan Yamin, Hazim Bukamur, Fadi Alkhankan, Yousef Shweihat, Fuad Zeid

Internal Medicine

Pulmonary alveolar microlithiasis is rare disease characterized by accumulation of calcium phosphate microlithis in the alveoli. The pathogenesis relates to mutation in the gene SLC34A2 (solute carrier family 34 member 2) located on chromosome 4p15.2, which produces a defective sodium-phosphate cotransporter in alveolar epithelial type-2 cells, making these cells unable to clear phosphorus released during recycling of surfactant.

Prevention And Mitigation Of Congenital Toxoplasmosis: Economic Costs And Benefits In Diverse Settings, Branko Bobić, Isabelle Villena, Eileen Stillwaggon

Economics Faculty Publications

Congenital toxoplasmosis (CT), the result of a primary infection of pregnant women with Toxoplasma gondii which was transmitted to the fetus, may result in mild to deep injuries occurring in the newborn or later in its development or in adolescence. The visual and cognitive impairment that can result imposes substantial economic costs on the individual and society. Numerous observational studies favor the conclusion that, with preventive measures currently available, it is possible to reduce the incidence of infections in pregnant women, the incidence of fetal infection by preventing transplacental transmission, and the gravity of injury in infected newborns. Treatment of …

Healthcare Access And Poverty Among Central Appalachian Residents, Kacey M. Lefevers

Kentucky Journal of Undergraduate Scholarship

Healthcare access is an important shaping force in the lives of Appalachian people. Appalachians often face both inadequate availability of medical facilities and poverty, which limits access to health insurance and therefore healthcare. This results in reduced life expectancy and health disparity. In this study, the author examines relationships between adequate healthcare and access to healthcare among Appalachian residents. Using a convenience sample of Appalachian residents, the author finds that income, education, and being an Appalachian resident have unique impacts on healthcare access or perceptions of healthcare in general.

Twelve Tips For Enhancing Student Engagement., Harm Peters, Marko Zdravkovic, Manuel João Costa, Antonio Celenza, Kulsoom Ghias, Debra Klamen, Liz Mossop, Michael Rieder, Vishna Devi Nadarajah, Danai Wangsaturaka, Martin Wohlin, Margot Weggemans

Paediatrics Publications

Student engagement refers to a broad range of activities where students participate in management, education, research, and community activities within their institutions. It is a mutually beneficial collaborative approach between students and their institutions. This article provides practical advice for the implementation or further development of student engagement at medical, dental, and veterinary schools. The tips provided are based on the experiences of a group of universities recently recognized for best practice in student engagement, and are supported by evidence from the literature. The tips cover overarching themes which include the creation of an institutional culture and formal framework for …

External Cold And Vibration For Pain Management Of Children Undergoing Needle-Related Procedures In The Emergency Department: A Randomised Controlled Non-Inferiority Trial Protocol., Ariane Ballard, Christelle Khadra, Samara Adler, Evelyne D Trottier, Benoit Bailey, Naveen Poonai, Jean Théroux, Sylvie Le May

Paediatrics Publications

INTRODUCTION: Needle-related procedures are considered as the most important source of pain and distress in children in hospital settings. Considering the physiological and psychological consequences that could result from these procedures, management of pain and distress through pharmacological and non-pharmacological methods is essential. Therefore, it is important to have interventions that are rapid, easy-to-use and likely to be translated into clinical practice for routine use. The aim of this study will be to determine whether a device combining cold and vibration (Buzzy) is non-inferior to a topical anaesthetic (liposomal lidocaine 4% cream) for pain management of children undergoing needle-related procedures …

Unanticipated Admissions To Paediatric Cardiac Critical Care After Cardiac Catheterisations., Erin Peebles, Michael R Miller, Lee N Benson, Tilman Humpl

Paediatrics Publications

OBJECTIVES: Cardiac catheterisation is commonly used for diagnosis and therapeutic interventions in paediatric cardiology. The inherent risk of the procedure can result in unanticipated admissions to critical care. Our goals were to provide a qualitative description of characteristics and evaluation of children admitted unexpectedly to the cardiac critical care unit (CCCU).

METHODS: A retrospective single centre review of cardiac catheterisation procedures was done between 1 January, 2003 and 30 April, 2013.

RESULTS: Of 9336 cardiac catheterisations performed, 146 (1.6%) were admitted from the catheterisation laboratory to the CCCU and met inclusion criteria. Of these 146 patients, 117 (1.3%) met criteria …

Poly(Ester Amide) Particles For Controlled Delivery Of Celecoxib, Ian J. Villamagna, Trent N. Gordon, Mark B. Hurtig, Frank Beier, Elizabeth R. Gillies

Physiology and Pharmacology Publications

© 2019 Wiley Periodicals, Inc. Many potential pharmacological treatments for osteoarthritis can result in undesirable side effects due to the systemic administration of drugs, making the direct delivery of drugs to joints an attractive alternative. Poly(ester amide)s (PEAs) have been shown to exhibit promising properties for the development of particle-based intra-articular delivery vehicles. However, a limited range of PEA structures has been investigated. In this study, we prepared and characterized the properties of two different PEA particles composed of l-phenylalanine, sebacic acid, and either 1,4-butanediol or 1,8-octanediol (PBSe and POSe, respectively). The anti-inflammatory drug celecoxib (CXB) was encapsulated into the …

Use Of A Radial Artery ‘Slender’ Sheath For Facilitating Transfemoral Arterial Access For Neuroendovascular Embolization In A Very Young Infant, Timothy L. Miao, Enriqueta Lucar Figueroa, Khalid Bajunaid, Michael Mayich, Sandrine De Ribaupierre, Sachin K. Pandey

Paediatrics Publications

Pediatric neuroendovascular procedures are increasingly performed as several studies have shown the safety of these interventions. In the literature, an upper limit of 4 French catheter size is conventionally used for femoral access in neuroangiography of very young infants. However, this constraint in luminal size may not allow for more complex procedures. We present the previously unreported use of a radial 5 French slender catheter with ultrathin walls for femoral access for aneurysm embolization in a 3-month-old boy presenting with left M2 aneurysm rupture.

Involuntary Hospitalization Among Young People With Early Psychosis: A Population-Based Study Using Health Administrative Data., Rebecca Rodrigues, Arlene G Macdougall, Guangyong Zou, Michael Lebenbaum, Paul Kurdyak, Lihua Li, Salimah Z Shariff, Kelly K Anderson

Epidemiology and Biostatistics Publications

OBJECTIVE: Early psychosis is an important window for establishing long-term trajectories. Involuntary hospitalization during this period may impact subsequent service engagement in people with newly diagnosed psychotic disorder. However, population-based studies of involuntary hospitalization in early psychosis are lacking. We sought to estimate the proportion of people aged 16 to 35 years with early psychosis in Ontario who are hospitalized involuntarily at first admission, and to identify the associated risk factors and outcomes.

METHODS: Using linked population-based health administrative data, we identified incident cases of non-affective psychosis over a five-year period (2009-2013) and followed cases for two years to ascertain …

Maga Expression Attenuates Iron Export Activity In Undifferentiated Multipotent P19 Cells, Linshan Liu, Kobra Alizadeh, Sarah C. Donnelly, Praveen Dassanayake, Tian Tian Hou, Rebecca Mcgirr, R. Terry Thompson, Frank S. Prato, Neil Gelman, Lisa Hoffman, Donna E. Goldhawk

Bone and Joint Institute

© 2019 Liu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Magnetic resonance imaging (MRI) is a non-invasive imaging modality used in longitudinal cell tracking. Previous studies suggest that MagA, a putative iron transport protein from magnetotactic bacteria, is a useful gene-based magnetic resonance contrast agent. Hem-agglutinin-tagged MagA was stably expressed in undifferentiated embryonic mouse teratocarcinoma, multipotent P19 cells to provide a suitable model for tracking these cells during differentiation. Western blot …

Lateral Compartment Contact Pressures Do Not Increase After Lateral Extra-Articular Tenodesis And Subsequent Subtotal Meniscectomy, Tomoyuki Shimakawa, Timothy A. Burkhart, Cynthia E. Dunning, Ryan M. Degen, Alan M. Getgood

Bone and Joint Institute

© The Author(s) 2019. Background: Modified Lemaire lateral extra-articular tenodesis (LET) has been proposed as a method of addressing persistent anterolateral rotatory laxity after anterior cruciate ligament (ACL) reconstruction (ACLR). However, concerns remain regarding the potential for increasing lateral compartment contact pressures. Purpose: To investigate changes in tibiofemoral joint contact pressures after isolated ACLR and combined ACLR plus LET with varying states of a lateral meniscal injury. Study Design: Controlled laboratory study. Methods: Eight fresh-frozen cadaveric knee specimens (mean age, 60.0 ± 3.4 years) were utilized for this study, with specimens potted and loaded on a materials testing machine. A …

The Neural Association Between Arithmetic And Basic Numerical Processing Depends On Arithmetic Problem Size And Not Chronological Age, Anna A. Matejko, Daniel Ansari

Brain and Mind Institute Researchers' Publications

© 2019 The Authors The intraparietal sulcus (IPS) is thought to be an important region for basic number processing (e.g. symbol-quantity associations) and arithmetic (e.g. addition). Evidence for shared circuitry within the IPS is largely based on comparisons across studies, and little research has investigated number processing and arithmetic in the same individuals. It is also unclear how the neural overlap between number processing and arithmetic is influenced by age and arithmetic problem difficulty. This study investigated these unresolved questions by examining basic number processing (symbol-quantity matching) and arithmetic (addition) networks in 26 adults and 42 children. Number processing and …

Resonate: Reflections And Recommendations On Implicit Biases Within The Ismrm, Esther A.H. Warnert, Krishna Nayak, Ravi Menon, Curt Rice, John Port, Elizabeth A. Morris, Daniel K. Sodickson, Pia Sundgren, Karla L. Miller, Udunna C. Anazodo

Brain and Mind Institute Researchers' Publications

No abstract provided.

The Experiences Of Physical Rehabilitation In Individuals With Spinal Cord Injuries: A Qualitative Thematic Synthesis., Janelle Unger, Hardeep Singh, Avril Mansfield, Sander L Hitzig, Erica Lenton, Kristin E Musselman

Physical Therapy Publications

PURPOSE: The purpose of this thematic synthesis review was to identify and synthesise published qualitative research on the perspectives of individuals with spinal cord injuries with respect to physical rehabilitation interventions.

MATERIALS AND METHODS: The peer-reviewed literature was searched across seven databases and identified abstracts were independently screened by two reviewers. A thematic synthesis methodology was used to code and synthesise the results from the included studies.

RESULTS: In total, 7233 abstracts were identified; 31 articles were selected for inclusion, representing 26 physical rehabilitation interventions. The methodological quality of studies was moderate (Standards for Reporting Qualitative Research mean ± standard …

The University Of New Mexico Orthopaedics Research Journal 2019, Unm Department Of Orthopaedic Surgery

UNM Orthopaedic Research Journal

No abstract provided.

Pediatric Emergency Department Poster - 2019, Ashley Notartomason Md, Marcella Jewell Md, Joeli Hettler Md

Research and Education Posters

Pediatric Emergency Department Poster - 2018

Department Of Internal Medicine-Pediatrics Posters - 2019, Elizabeth Peacock-Chambers Md, Briana Jurkowski, Michael Moran, Caroline Clark Msw, Kelsy Kaman Md, Jhill Shah Do, Taylor Koerner Md, Chandrika Sridharamurthy Md, Crystal Cobb Do, Angela Slick Md, Deirdre Lewis Md

Research and Education Posters

Department of Internal Medicine-Pediatrics Posters - 2019

Palliative Care Posters - 2019, Christina Fitch Md, Diane Dietzen Md, Erin J. Salvador Md, Vaness Washington-Jenkins Rn, Amir Abou-Aitah Md, Michael Ehresman, Maura Brennan Md

Research and Education Posters

Palliative Care Posters - 2019

Ob Gyn Posters - 2019, Sophia Bachilova Md, Lisa Ashcraft, Tayyab Rahil, Vida Rastegar, Cynthia Sites Md, Nicole O. Afuape Md, Daniel E. Kirton Md, Heather Sankey Md, Heather H. Love

Research and Education Posters

OB GYN Posters - 2019

Medicine Posters - 2019, Mary Jo S. Farmer Md, Kanval Shah Md, Mihaela Tiru Md, Vida Rastegar, Kirti Joshi Md, Peter Lindenauer, Tara Lagu, Mihaela Stefan Md, Eric Romo Ba, Donna M. Wilson, Alexander Y. Walley Md, Traci C. Green Ba, Josiah D. Rich Md, Susan Ramsey Phd, Jeffrey Bratberg Pharmd, Michelle Mckenzie Mph, Haley Guhn-Knight Ba, Peter Friedmann Md

Research and Education Posters

Medicine Posters - 2019

Radiology Posters - 2019, Hamed Jalaeian, Bertrand Janne D'Othee Md, Pouya Aghajafari Md, Daniel Hynes Md, Amy Oliveira Md, Seth Andrews Do, Christina Duffin Md, Daniel Kowal Md

Research and Education Posters

Radiology Posters - 2019

Berst Academy Poster - 2019, Angela T. Sweeney, Rebecca Blanchard Phd

Research and Education Posters

BERST Academy (Baystate Education Research and Scholarship of Teaching) Poster 2019

Nicu Poster - 2019, Veronica Alix Md, Mansi James Do, Anthony Jackson Md, Paul Visintainer, Rachana Singh Md

Research and Education Posters

NICU Poster - 2019

Anesthesiology Posters - 2019, Stanlies D'Souza, Nishal D'Souza Md, Brian Mason Md, Long-Chau Van Do, Ruth E. Ebert Md, Richard Nguyen Md, Lakshmi Madabhushi Md, Erica Tramontana Do, Sarafina Kankam Md

Research and Education Posters

Anesthesiology Posters

Pvlsi (Pioneer Valley Life Sciences Institute) Posters - 2019, Kelly Gregory, Jennifer Ser-Dolansky, Sallie Schneider Phd, Briana Leung, Kelly Gregory, Salih Toker Md, Stephanie M. Morin, Jessica Nieves, Amye Black, Gat Rauner, Sandra Haddad, D. Joseph Jerry, Munther Queisi Md, Ali Shami Md, Maryam Hasan Md

Research and Education Posters

PVLSI (Pioneer Valley Life Sciences Institute) Posters - 2019

The Genome Of C57bl/6j "Eve", The Mother Of The Laboratory Mouse Genome Reference Strain., Vishal Kumar Sarsani, Narayanan Raghupathy, Ian T Fiddes, Joel Armstrong, Francoise Thibaud-Nissen, Oraya Zinder, Mohan Bolisetty, Kerstin Howe, Doug Hinerfeld, Xiaoan Ruan, Lucy B. Rowe, Mary Barter, Guruprasad Ananda, Benedict Paten, George M. Weinstock, Gary Churchill, Michael V. Wiles, Valerie A Schneider, Anuj Srivastava, Laura G Reinholdt

Faculty Research 2019

Isogenic laboratory mouse strains enhance reproducibility because individual animals are genetically identical. For the most widely used isogenic strain, C57BL/6, there exists a wealth of genetic, phenotypic, and genomic data, including a high-quality reference genome (GRCm38.p6). Now 20 years after the first release of the mouse reference genome, C57BL/6J mice are at least 26 inbreeding generations removed from GRCm38 and the strain is now maintained with periodic reintroduction of cryorecovered mice derived from a single breeder pair, aptly named Adam and Eve. To provide an update to the mouse reference genome that more accurately represents the genome of today's C57BL/6J …

Effects Of Igf-1 Isoforms On Muscle Growth And Sarcopenia., Francesca Ascenzi, Laura Barberi, Gabriella Dobrowolny, Aline Villa Nova Bacurau, Carmine Nicoletti, Emanuele Rizzuto, Nadia Rosenthal, Bianca Maria Scicchitano, Antonio Musarò

Faculty Research 2019

The decline in skeletal muscle mass and strength occurring in aging, referred as sarcopenia, is the result of many factors including an imbalance between protein synthesis and degradation, changes in metabolic/hormonal status, and in circulating levels of inflammatory mediators. Thus, factors that increase muscle mass and promote anabolic pathways might be of therapeutic benefit to counteract sarcopenia. Among these, the insulin-like growth factor-1 (IGF-1) has been implicated in many anabolic pathways in skeletal muscle. IGF-1 exists in different isoforms that might exert different role in skeletal muscle. Here we study the effects of two full propeptides IGF-1Ea and IGF-1Eb in …