Medicine and Health Sciences Commons^™

Dominican Sisters Quality Of Life Assessment, Eva Vanartsen

Biomedical Sciences Undergraduate Research

Background: The quality of life in older women has been found to decrease with poverty, poor health, decreased access to healthcare and low education, while marriage and children can both improve or decrease the quality of life. The information on the quality of life of older women living in faith based communities is lacking.

Objectives: The purpose of this study was to explore the quality of life and factors impacting quality of life in Sisters living in an assisted living facility.

Methods: The short form 36 Health Survey Questionnaire (SF-36) was used to measure quality of life of the Dominican …

Bone Scintigraphy Imaging Of Cardiac Amyloidosis, Issa Menge Kuria, Samuel Gitau, Khalid Makhdomi

Imaging & Diagnostic Radiology, East Africa

Transthyretin-related cardiac amyloidosis (ATTR) amyloidosis is an aggressive, rapidly progressive, and fatal disease, for which several promising therapies are in development. This condition is frequently underdiagnosed because of the limited specificity of echocardiography and the traditional requirement for histological diagnosis. It is well known that 99mtechnetium-labeled bone scan radiotracers can localize in the myocardial amyloid deposits, but the use of this imaging modality to differentiate between the two subtypes has only lately been revisited. We report a case of a 76-year-old man with a clinical diagnosis of amyloidosis who underwent a bone scan that had features of ATTR amyloidosis. To …

Role Of Dietary Flavonoid Compounds In Driving Patterns Of Microbial Community Assembly, Kerry L. Ivey, Andrew T. Chan, Jacques Izard, Aedin Cassidy, Geraint B. Rogers, Eric B. Rimm

Department of Food Science and Technology: Faculty Publications

Flavonoids are a group of polyphenolic dietary compounds found in many different plant-based foods. There is increasing evidence that higher flavonoid intake may be causally linked to a reduced risk of cardiovascular disease and other chronic diseases. The bioactivity and bioavailability of many dietary flavonoids can be influenced by gastrointestinal microbiome metabolism. However, the role that habitual flavonoid intake plays in shaping the human gut microbiome is poorly understood. We describe an application of an ecosystem-based analytic approach to nutritional, microbiome, and questionnaire data from a cohort of more than 240 generally healthy adult males to assess the role of …

Landscape Factors That Influence European Starling (Sturnus Vulgaris) Nest Box Occupancy At Nasa Plum Brook Station (Pbs), Erie County, Ohio, Usa, Morgan Pfeiffer, Thomas W. Seamans, Bruce N. Buckingham, Bradley F. Blackwell

United States Department of Agriculture Wildlife Services: Staff Publications

During the last decade at NASA Plum Brook Station (PBS), Erie County, Ohio, United States, there has been a nearly 50% decrease in European Starling (Sturnus vulgaris) occupancy (nests with ≥1 egg) of nest boxes designed to be used by starlings. Increased availability of natural cavities, from invertebrate pests, might have altered nest box occupation rates. It was hypothesized that starling nest box occupation rates would be a function of an index of potentially suitable tree cavities for nesting starlings, the semi-colonial nature of breeding starlings, and access to foraging areas (e.g., mowed lawns near buildings). Specifically, it was predicted …

Nursing Care For Adolescents With Cancer Relapse Receiving Palliative Care(การพยาบาลผู้ป่วยวัยรุ่นโรคมะเร็งกลับเป็นซ้ำที่ได้รับการดูแลแบบประคับประคอง), Thipkasorn Wannaphak

Journal of Nursing Research, Innovation, and Health

This article is aimed at providing nursing care for adolescents with cancer relapse receiving palliative care due to their physical and mental suffering. The relapse is considered a severe condition as the cancer cell has spread to other organs which are often incurable, depending on the patients' health. Adolescents with cancer relapse often encountered late effects from the previous treatment as well as side effects from chemotherapy in the new treatment which results in deterioration in health. Intensive treatment for patients in this group is difficult to success and also decrease the quality of patient's life. Palliative care as patients …

Health Management Of Diabetes Risk Group In Ban Muang Whan : A Qualitative Research Perspective(การจัดการสุขภาพของกลุ่มเสี่ยงโรคเบาหวานในชุมชนบ้านม่วงหวาน : มุมมองจากการศึกษาเชิงคุณภาพ), Arissara Sukwatjanee, Anchaleeporn Amatayakul

Journal of Nursing Research, Innovation, and Health

Purpose: To explore health management of diabetes risk group Design: Qualitative researchMethods: The research participants comprised of 75 people, including people, who were diabetes risk group and their families, sub-district health promoting hospital staff, community leaders, village health volunteers, monks, teachers and food vendors in Ban Muang Whan community. The research instruments included 1) the in depth-interviewed guideline, 2) the group discussion guideline, 3) the brain storm guideline, 4) the observation guideline, and 5) the field note. Data were analyzed using content analysis method. Findings: People, who were diabetes risk group, provided self-care including controlled diet, controlled body weight, exercise, …

The Effect Of Self-Care Enhancement Program On Post-Bariatric Surgery Self-Care Behaviors Among Morbid Obese Patients(ผลของโปรแกรมส่งเสริมการดูแลตนเองต่อพฤติกรรมการดูแลตนเองภายหลังการผ่าตัดลดน้ำหนักของผู้ป่วยโรคอ้วน), Sipaphan Lavasut, Rungrawee Navicharern

Journal of Nursing Research, Innovation, and Health

Purpose: 1) To study the self-care behaviors post-bariatric surgery among morbid obese patients who received the self-care enhancement program. 2) To compared the self-care behaviors post-bariatric surgery among the control group and the experimental group.Design: Quasi-experimental research.Methods: The 30 patients were male and female with morbid obese patients, aged between 18-59 years old, receiving post-bariatric surgery at King Chulalongkorn Memorial Hospital. They were hospitalized and assigned to the control and the experimental group (15 persons in each group), and matched pair by gender, age and type of operation. The experimental group received the self-care enhancement program based on Orem's self-care, …

The Effect Of Empowerment Program On Late Phase Postoperative Recovery Among Post Lumbar Spine Surgery Patients(ผลของโปรแกรมเสริมสร้างพลังอำนาจต่อการฟื้นสภาพหลังผ่าตัดระยะท้ายในผู้ป่วยที่ได้รับการผ่าตัดกระดูกสันหลังระดับเอว), Rattiya Toeysri, Pachanut Nanthaitaweekul

Journal of Nursing Research, Innovation, and Health

Purpose: To study the effects of empowerment program on late phase postoperative recovery among post lumbar spine surgery patients.Design: Quasi-experimental researchMethods: The participants were 46 patients aged 30-59 years old, under postoperative lumbar spine surgery were admitted into the Neurosurgery ward at Prasat Neurological Institute. Randomly selected and assigned into either experimental and control group comprised 23 patients in each group with matching technique for age, pain scale, and level of lumbar spine surgery. The research instruments consisted of the empowerment program base on the concept of Gibson, notebook with activity, and postoperative recovery profile for lumbar spine surgery patients. …

The Factors Related To Hiv Prevention Behavior Among Myanmarese Youth Migrant Workers(ปัจจัยที่มีความสัมพันธ์กับพฤติกรรมการป้องกันการติดเชื้อเอชไอวีของเยาวชนแรงงานข้ามชาติชาวเมียนมา), Ekkalak Faksook, Pregamol Rutchanagul, Wanalada Thongbai

Journal of Nursing Research, Innovation, and Health

Purpose: To investigate factors related to HIV preventive behaviors among Myanmarese youth migrant workers. Design: descriptive correlation research studyMethod: The sampling consisted of 120 young Myanmar migrant workers Visited to the hospital under the Department of Medical Services, Bangkok area between October and November 2018. Data were collected using a set of questionnaires. The questionnaires included questionnaires about personal information, knowledge, attitude toward HIV infection, perceived susceptibility to HIV infection, self-efficacy for HIV prevention and HIV prevention behavior. Data were analyzed using descriptive and inferential statistics. Correlations were identified using the Pearson product-moment correlation coefficient, and the point biserial correlation …

Improving Recognition And Reporting Of Adverse Drug Reactions In The Nicu: A Quality Improvement Project., Betsy Cammack, Alexandra Oschman, Tamorah R. Lewis Md Phd

Manuscripts, Articles, Book Chapters and Other Papers

Adverse drug reactions (ADRs) are under-recognized and under-reported in the Neonatal Intensive Care Unit (NICU) population, with up to 95% of all ADRs not reported. Compared with non-elderly adults, pediatric patients are 3 times more likely to experience an ADR, with varying rates from 0.6% to 16.8%. The Children's Mercy NICU has an ADR rate of 0.29% (2015). This high rate presents an opportunity to increase recognition and reporting, and improve characterization of ADRs in the NICU.

Methods: The primary aim of this quality improvement project was for 70% of patients who received specified medications (indomethacin, dexmedetomidine, fentanyl, lorazepam, dexamethasone, …

An Interdisciplinary Framework For Impacting Older Adults Health And Physical Activity, Christopher J. Dondzila, Elaine Vandoren

Open Access Publishing Support Funded Articles

The exploration of feasible and cost-effective strategies is warranted to mitigate rising healthcare costs and lessen the impact of chronic diseases, functional decline, and disability in older adults. The overwhelming sedentariness of older adults is accompanied by a lack of expertise by healthcare professionals in exercise programming that acknowledge factors influencing physical activity (PA) patterns. We present a framework for a nursing/exercise science interdisciplinary effort to increase PA and improve health in older adults via the delivery of individually tailored exercise programming for an 8-week intervention. Results from this study will be integral in translating effective interdisciplinary efforts across diverse …

Significance Of Capnography In Pediatric Post Anesthesia Care, Deborah Renee Whitley

Doctoral Dissertations and Projects

Updated clinical guidelines and professional practice standards for pediatric post-anesthesia care call for the use of capnography until the patient is awake. The purpose of this project was to champion the implementation of capnography in the pediatric post-anesthesia care unit at the project site. Monitoring capnography in addition to pulse oximetry for all pediatric post-anesthesia patients until awake was the practice change implemented. Capnography led to an increase in the number of appropriate respiratory-related nursing care interventions provided, earlier response to changes in respiratory status, and a decrease in the pediatric post-anesthesia care unit length of stay. The implications for …

Shingrix Education For Providers, Lindsey Hanks Buzzeo

Doctoral Dissertations and Projects

Shingles is a prevalent disease within the overall population, and incidence in North America continues to increase. Shingles is commonly found in older adults 60 years of age and older and can recur two or three times. Shingrix was released in 2017 as a recombinant vaccine for prevention of shingles. Despite its benefits, this vaccine has not been recommended by many prescribing providers. Research has shown that an effective education program improves attitudes and misconceptions related to vaccines and can increase prescribing rates. An education program was created to share with prescribing providers to improve overall knowledge and recommendation rates …

Sepsis Education Utilizing ‘Sepsis Alert’ Checklist To Support The Adherence Of Early Management Bundle In The Emergency Department, Jean Jun

Doctoral Dissertations and Projects

Early recognition and timely management of sepsis is a priority within hospitals due to its direct impact on patients’ outcomes. It is critical for healthcare providers to be educated and aware of the signs and symptoms of sepsis. The emergency department (ED) is the forefront of the hospital where majority of patients with sepsis are assessed and either discharged or admitted into the hospital. Therefore, it is critical for ED nurses to be educated in the early signs of sepsis and follow evidence-based practice guidelines when managing these patients. The project leader implemented a sepsis education intervention aimed at clinical …

Improving The Youth Hiv Prevention And Care Cascades: Innovative Designs In The Adolescent Trials Network For Hiv/Aids Interventions, Sylvie Naar, Michael G Hudgens, Ron Brookmeyer, April Idalski Carcone, Jason Chapman, Shrabanti Chowdhury, Andrea Ciaranello, W Scott Comulada, Samiran Ghosh, Keith J Horvath, Ladrea Ingram, Sara Legrand, Cathy J Reback, Kit Simpson, Bonita Stanton, Tyrel Starks, Dallas Swendeman

Faculty, Staff and Student Publications

Dramatic decreases in HIV transmission are achievable with currently available biomedical and behavioral interventions, including antiretroviral therapy and pre-exposure prophylaxis. However, such decreases have not yet been realized among adolescents and young adults. The Adolescent Medicine Trials Network (ATN) for HIV/AIDS interventions is dedicated to research addressing the needs of youth at high risk for HIV acquisition as well as youth living with HIV. This article provides an overview of an array of efficient and effective designs across the translational spectrum that are utilized within the ATN. These designs maximize methodological rigor and real-world applicability of findings while minimizing resource …

Unraveling The Functional Role Of The Orphan Solute Carrier, Slc22a24 In The Transport Of Steroid Conjugates Through Metabolomic And Genome-Wide Association Studies, Sook Wah Yee, Adrian Stecula, Huan-Chieh Chien, Ling Zou, Elena V Feofanova, Marjolein Van Borselen, Kit Wun Kathy Cheung, Noha A Yousri, Karsten Suhre, Jason M Kinchen, Eric Boerwinkle, Roshanak Irannejad, Bing Yu, Kathleen M Giacomini

Faculty, Staff and Student Publications

Variation in steroid hormone levels has wide implications for health and disease. The genes encoding the proteins involved in steroid disposition represent key determinants of interindividual variation in steroid levels and ultimately, their effects. Beginning with metabolomic data from genome-wide association studies (GWAS), we observed that genetic variants in the orphan transporter, SLC22A24 were significantly associated with levels of androsterone glucuronide and etiocholanolone glucuronide (sentinel SNPs p-value

Pm25 Metal Constituent Exposure And Stillbirth Risk In Harris County, Texas, Amal Rammah, Kristina W Whitworth, Inkyu Han, Wenyaw Chan, Elaine Symanski

Faculty, Staff and Student Publications

There is limited evidence on the role of exposure to chemical constituents of fine particulate matter (PM

Effects Of Rescheduling On Patient No-Show Behavior In Outpatient Clinics, Jiayi Liu, Jingui Xie, Kum Khiong Yang, Zhichao Zheng

Research Collection Lee Kong Chian School Of Business

We study the effects of rescheduling on no-show behavior in an outpatient appointment system for both new and follow-up patients. Previous literature has primarily focused on new patients and investigated the role of waiting time on no-show probability. We offer a more nuanced understanding of this costly phenomenon. Using comprehensive clinical data, we demonstrate that for follow-up patients, their no-show probability decreases by 10.9 percentage points if their appointments were rescheduled at their own request, but increases by 6.2 percentage points if they were rescheduled by the clinic. New patients, in contrast, are more concerned about waiting time and less …

Ossification Of The Posterior Longitudinal Ligament: Surgical Approaches And Associated Complications., Jeffery Head, George Rymarczuk, Geoffrey Stricsek, Lohit Velagapudi, Christopher Maulucci, Christian Hoelscher, Md, James Harrop

Department of Neurosurgery Faculty Papers

Ossification of the posterior longitudinal ligament (OPLL) is a rare but potentially devastating cause of degenerative cervical myelopathy (DCM). Decompressive surgery is the standard of care for OPLL and can be achieved through anterior, posterior, or combined approaches to the cervical spine. Surgical correction of OPLL via any approach is associated with higher rates of complications and the presence of OPLL is considered a significant risk factor for perioperative complications in DCM surgeries. Potential complications include dural tear (DT) and subsequent cerebrospinal fluid leak, C5 palsy, hematoma, hardware failure, surgical site infections, and other neurological deficits. Anterior approaches are technically …

Statement On Imaging And Pulmonary Hypertension From The Pulmonary Vascular Research Institute (Pvri), David G. Kiely, David L. Levin, Paul M. Hassoun, Dunbar Ivy, Pei-Ni Jone, Jumaa Bwika, Steven M. Kawut, Jim Lordan, Angela Lungu, Jeremy A. Mazurek

Internal Medicine, East Africa

Pulmonary hypertension (PH) is highly heterogeneous and despite treatment advances it remains a life-shortening condition. There have been significant advances in imaging technologies, but despite evidence of their potential clinical utility, practice remains variable, dependent in part on imaging availability and expertise. This statement summarizes current and emerging imaging modalities and their potential role in the diagnosis and assessment of suspected PH. It also includes a review of commonly encountered clinical and radiological scenarios, and imaging and modeling-based biomarkers. An expert panel was formed including clinicians, radiologists, imaging scientists, and computational modelers. Section editors generated a series of summary statements …

Evaluation Of Prescribing Patterns Of Long-Acting Injectable Antipsychotics Within A Community Health System., Jared Netley Pharmd, Mpa, Bcps, Jamie Gaul Pharmd, Bcps, Chelsea L Ferguson Pharmd

Parkview Pharmacy Department

PURPOSE/BACKGROUND: Long-acting injectable antipsychotics (LAIAs) are used in the management of schizophrenia, bipolar disorder, and related psychiatric conditions. The efficacy of LAIAs has been established in randomized controlled trials; however, usage of LAIAs outside of randomized controlled trials may not correlate to naturalistic prescribing habits. The purpose of this analysis was to evaluate the prescribing patterns of LAIAs within our health system and identify any inconsistencies between medications' published labeling information and clinical practice.

METHODS/PROCEDURES: All patients who received a LAIA at the time of the analysis were included for review. Areas of inconsistency between the prescribed LAIA and each …

Inspire : Vol 2, Issue 9, Department Of Medicine

INSPIRE – Department of Medicine Archives

Content

• Message From The Chair
• Women in Global Health (WGH) Pakistan Chapter
• Faculty Development Workshop Series
• Department of Medicine at National and International Forums Featured Faculty Profile Dr. Rabeea Azmat “ There is no shortcut to success!”
• What Are Academics Around the World Reading This Month?
• Publications

Morning Cortisol As An Alternative To Short Synecthan Test For The Diagnosis Of Primary Adrenal Insufficiency, Imran Ulhaq, Tauseef Ahmad, Adeel Khoja, Najmul Islam

Section of Diabetes, Endocrinology and Metabolism

Objective: To determine 7-9 am serum cortisol less than 5mcg/dl is an independent reliable confirmatory test for the diagnosis of primary adrenal insufficiency (PAI).

Methods: A total of 164 patients who visited the outpatient or inpatient department of Aga Khan University Hospital from June 2011 to June 2017 were included for the study. All those patients whose levels came out less than 5mcg/dl were recruited for the study and they all underwent SST. Other demographic and laboratory data were also recorded.

Results: The sensitivity of morning cortisol for diagnosis of PAI is 100% if levels are <1mcg/dl and decreases to 71.88% if levels are up to 5mcg/dl.

Conclusion: Morning cortisol is …

Etiology And Clinical Patterns Of Uveitis At Three Ophthalmic Clinics In Tajikistan, Sayyora Yuldasheva, Saidbeg Satorov, Shekhratdzon Satorov, Vyacheslav Dushenkov

Publications and Research

A prospective observational study was conducted at three ophthalmic clinics to assess the clinical patterns and etiology of uveitis in the Central Asia Republic of Tajikistan. All patients underwent physical and ophthalmologic examinations. Extensive efforts were made to determine the etiology of uveitis, including workups for Behçet's Disease (BD) and Vogt–Koyanagi–Harada (VKH) syndrome. All patients were tested for the presence of HLA-B27. Presence and/or history of tuberculosis and syphilis were ruled out. HSV, CMV, Chlamydia trachomatis and HIV antibody titers were determined by ELISA. Uveitis was diagnosed in 51 patient ages 14 to 60 were with women accounted for 60.8%. …

Effect Of Biomimetic Mineralization On Enamel And Dentin: A Raman And Edx Analysis, Arndt Guentsch, Mina D. Fahmy, Contanze Wehrle, Sandor Nitzsche, Jürgen Popp, David C. Watts, Stefan Kranz, Christoph Krafft, Bernd W. Sigusch

School of Dentistry Faculty Research and Publications

Objective

To investigate the effect of an experimental biomimetic mineralization kit (BIMIN) on the chemical composition and crystallinity of caries-free enamel and dentin samples in vitro.

Methods

Enamel and dentin samples from 20 human teeth (10 for enamel; 10 for dentin) were divided into a control group without treatment and test samples with BIMIN treatment. Quantitative analysis of tissue penetration of fluoride, phosphate, and calcium was performed using energy-dispersive X-ray spectroscopy (EDX). Mineralization depth was measured by Raman spectroscopy probing the symmetric valence vibration near 960 cm⁻¹ as a marker for crystallinity. EDX data was statistically analyzed using …

Infant With Protein C Deficiency And Stroke In The Setting Of Iron Deficiency Anemia, Tahseen Jalal Karim, Dustin J Paul, Regina M Troxell, Rajan Patel, Ian J Butler

Faculty, Staff and Student Publications

We report an 18-month-old infant with ischemic stroke, neurocognitive impairment, and psychomotor retardation in the setting of severe iron deficiency anemia. Although an uncommon outcome in anemic children, stroke is important to consider as a cause for developmental delay in children with iron deficiency anemia.

Epstein-Barr Virus-Positive Large Cell Neuroendocrine Carcinoma Of The Nasopharynx: Report Of One Case And Review Of The Literature, Zhenjian Cai, Mei Lin, Angel I Blanco, Jing Liu, Hui Zhu

Faculty, Staff and Student Publications

Epstein-Barr Virus (EBV)-positive neuroendocrine carcinoma (NEC) of the nasopharynx is exceedingly rare, only two cases have been reported in the literature. While EBV infection is strongly associated with nasopharyngeal carcinoma, which is carcinoma with squamous differentiation, the link between EBV and NEC is not well known, and can be diagnostically challenging. In this study, we report the third case of EBV-positive large cell NEC of nasopharynx with neck lymph node metastasis. The patient was treated with combined radiation and chemotherapy and showed complete clinical and radiological response. Similar treatment response has been reported in another patient with high stage EBV-positive …

Vitamin D Status And Risk Of Incident Tuberculosis Disease: A Nested Case-Control Study, Systematic Review, And Individual-Participant Data Meta-Analysis, Omowunmi Aibana, Chuan-Chin Huang, Said Aboud, Alberto Arnedo-Pena, Mercedes C Becerra, Juan Bautista Bellido-Blasco, Ramesh Bhosale, Roger Calderon, Silvia Chiang, Carmen Contreras, Ganmaa Davaasambuu, Wafaie W Fawzi, Molly F Franke, Jerome T Galea, Daniel Garcia-Ferrer, Maria Gil-Fortuño, Barbará Gomila-Sard, Amita Gupta, Nikhil Gupte, Rabia Hussain, Jesus Iborra-Millet, Najeeha T Iqbal, Jose Vicente Juan-Cerdán, Aarti Kinikar, Leonid Lecca, Vidya Mave, Noemi Meseguer-Ferrer, Grace Montepiedra, Ferdinand M Mugusi, Olumuyiwa A Owolabi, Julie Parsonnet, Freddy Roach-Poblete, Maria Angeles Romeu-García, Stephen A Spector, Christopher R Sudfeld, Mark W Tenforde, Toyin O Togun, Rosa Yataco, Zibiao Zhang, Megan B Murray

Faculty, Staff and Student Publications

BACKGROUND: Few studies have evaluated the association between preexisting vitamin D deficiency and incident tuberculosis (TB). We assessed the impact of baseline vitamins D levels on TB disease risk.

METHODS AND FINDINGS: We assessed the association between baseline vitamin D and incident TB in a prospective cohort of 6,751 HIV-negative household contacts of TB patients enrolled between September 1, 2009, and August 29, 2012, in Lima, Peru. We screened for TB disease at 2, 6, and 12 months after enrollment. We defined cases as household contacts who developed TB disease at least 15 days after enrollment of the index patient. …

Nuclear Receptor Subfamily 4 Group A Member 2 Inhibits Activation Of Erk Signaling And Cell Growth In Response To Β-Adrenergic Stimulation In Adult Rat Cardiomyocytes, Sadia Ashraf, Yassmin K Hegazy, Romain Harmancey

Faculty, Staff and Student Publications

Sustained elevation of sympathetic activity is an important contributor to pathological cardiac hypertrophy, ventricular arrhythmias, and left ventricular contractile dysfunction in chronic heart failure. The orphan nuclear receptor NR4A2 is an immediate early-response gene activated in the heart under β-adrenergic stimulation. The goal of this study was to identify the transcriptional remodeling events induced by increased NR4A2 expression in cardiomyocytes and their impact on the physiological response of those cells to sustained β-adrenergic stimulation. Treatment of adult rat ventricular myocytes with isoproterenol induced a rapid (<4 >h) increase in NR4A2 levels that was accompanied by a transient (<24 >h) increase …

Indications For Lung Transplant Referral And Listing, Omar Shweish, Goutham Dronavalli

Faculty, Staff and Student Publications

Lung transplantation is a valuable therapeutic option for many patients with severe lung disease who have exhausted other medical or surgical therapies. However, since lungs are not a manufacturable organ like artificial heart valves or left ventricular assist devices, and since they are a limited resource compared to number of patients requiring the organs, the Department of Health and Human Services set the Final Rule of organ allocation in 1998. This led to development and implementation of Lung Allocation Score (LAS) in 2005. The score broadly divides lung diseases into 4 diagnostic criteria with a coefficient factor given to each …