Medicine and Health Sciences Commons^™

Compare Healthcare Utilization In The First Three Years Of Life For Infants With Prenatal Opioid Exposure Based On Type Of Neonatal Care Received, Renee Robinson, Amanda Slaunwhite, Evelyn Rider, Janet Johnson, Amanda Walch

Journal of Health Disparities Research and Practice

Purpose/Background: Infants with prenatal opioid and other drug exposure often experience withdrawal symptoms known as neonatal abstinence syndrome (NAS). Some hospitals have modified clinical environments to promote recovery (reduced stimulation, nursery-like rooms, permitting rooming-in). While existing research has demonstrated efficacy of lower-stimulation environment, there is no known research evaluating longer-term implications of clinical environment on infant health beyond immediate neonatal period in states disproportionately affected by the opioid epidemic with diverse urban-rural populations such as Alaska.

Materials & Methods: The goal of this project is to determine whether supportive care decreases the likelihood of foster care placement from birth to …

Bridging The Rural-Urban Disparity: A Mixed-Methods Analysis Of Human Papillomavirus Vaccine Uptake In Montana, Sophia Newcomer

Journal of Health Disparities Research and Practice

Purpose/Background: Since introduction of the human papillomavirus (HPV) vaccine in 2006, national efforts to increase vaccine uptake have been largely successful in urban areas, but less effective in rural settings. As of 2017, HPV vaccine series initiation rates were 10.8% percentage points lower for adolescents residing in rural versus urban areas of the U.S. This disparity leaves rural youth at higher risk of developing of HPV- caused cancers and other diseases, including cervical cancer, tongue and throat cancers, and genital warts. In Montana, a predominantly rural state, only 49% of adolescents are up-to-date on the recommended 2-dose vaccine series, well …

Augmenting Exposure Therapy For Social Anxiety With Tdcs, Cynthia L. Lancaster, Samantha J. Meckes, Mollie A. Mcdonald, Marian E. Berryhill

Journal of Health Disparities Research and Practice

Purpose/Background: Exposure therapy is one of the most potent techniques available to treat social anxiety. However, studies suggest that exposure therapy only produces full remission in 20-50% of patients. Furthermore, laboratory conditioning and extinction studies suggest that fear responses toward individuals who differ from one's own ethnicity/race may be more resistant to extinction. Because activation of the medial prefrontal cortex has been associated with facilitating fear reduction during exposure therapy, we expect that targeting activation of this region with a stimulation technique called transcranial direct current stimulation (tDCS) may improve outcomes from exposure therapy for social anxiety. The present study …

Assessment Of Risk Factors For Health Disparities Among Latina Farm Workers, Cynthia Curl, Lisa Meierotto, Rebecca Som Castellano

Journal of Health Disparities Research and Practice

Purpose/Background: Latina farm workers may experience a unique intersection of social and environmental factors that are known to affect health and well-being. The disadvantages inherent in their gender, race and social class may be compounded by their immigration status, rural location and the hazards of farm work. We propose to identify the most critical risk factors for poor health facing this underserved and understudied population.

Materials & Methods: Our study uses a mixed-methods approach that combines qualitative data from focus groups (n=3 groups of 10 participants each) and semi-structured interviews (n=15) with quantitative and qualitative survey data (n=100) and biological …

The Female Cervicovaginal Mucosa Is A Unique Site For The Production Of Autoantibodies Associated With Rheumatoid Arthritis, Brian Cherrington, Heather Rothfuss, Kristen Demoruelle

Journal of Health Disparities Research and Practice

Purpose/Background: Women have a 3-fold higher incidence of rheumatoid arthritis (RA) and a lower likelihood of remission compared to men suggesting a gender disparity in the etiology of RA. In order to devise female specific prevention and treatment strategies, it is critical to understand the mechanism initiating the production of RA autoantibodies termed anti-citrullinated protein antibodies (ACPA). ACPA target proteins that are posttranslationally modified by a family of enzymes termed peptidylarginine deiminases (PADs), which convert arginine into citrulline. Research suggests that ACPA are generated at a mucosal site years before becoming systemic and causing clinical joint disease. Mucosal sites such …

Analysis Of Knee Motion To Prevent And Treat The Increasing Incidence Of Premature Knee Oa, Tyler Brown, Micah Drew, Samantha Krammer

Journal of Health Disparities Research and Practice

Purpose/Background: Osteoarthritis (OA) is a costly, debilitating musculoskeletal disease. A disparity in OA incidence in young individuals who don body borne load while physically active, such as service members, reportedly exists. Incidence of premature OA in service members is greater than twice the general population and steadily increasing at the knee. Moreover, there is disparity in knee OA incidence for female and African-American service members, who are 15%-25% more likely to develop the disease. A service member’s physical activity directly contributes to premature knee OA development. Specific knee locomotion biomechanics indicative of joint instability, including large and/or abrupt knee adduction …

¡Yo No Estoy Loco/A! Improving Treatment Engagement For Latinos Using An E-E Video, Lorraine T. Benuto, Frances Gonzalez, Rory Newlands, Jena Casas

Journal of Health Disparities Research and Practice

Purpose/Background: Approximately 30% of Latinos experience some form of psychiatric illness in their lifetime. Despite the high prevalence rate of mood disorders among Latinos and the availability of empirically supported treatments that target anxiety and depression, Latinos underutilize behavioral health services. Perceived stigma associated with the pursuit of behavioral health services disproportionately restricts mental health care in Latinos. The research team created an Entertainment- Education (E-E) telenovela-style video (in Spanish), which acted as the experimental intervention in the proposed project. The experimental intervention is based on the E-E model which incorporates health and educational messages in an entertaining, story-telling narrative …

Mountain West Clinical Translational Research-Infrastructure Network: Introduction, Parvesh Kumar

Journal of Health Disparities Research and Practice

The Mountain West (MW) Clinical Translational Research Infrastructure Network (CTR- IN) Program represents a consortium of all of the 13 major public universities across seven Institutional Development Awards (IDeA) states with the overall goal of increasing and enhancing research capacity. The MW CTR-IN Program covers 1/3^rd the U.S. land mass and almost 1/3^rd of all IDeA states stretching across 4 time zones. The 13 major U.S. public partner universities in the 7 IDeA states are as follows: University of Alaska at Anchorage (UAA), University of Alaska at Fairbanks (UAF), University of Montana (UM), Montana State University (MSU), University …

What's Happening: November 11, 2019, Maine Medical Center

What's Happening

No abstract provided.

Abstract 13987: Underutilization Of Oral Anticoagulant Therapy In At-Risk Patients With Atrial Fibrillation—Insights From A Multistate Healthcare System, Tyler J Gluckman, Amir Ali, Mansen Wang, Howard Mun, Sally Alfred, John L. Petersen

Articles, Abstracts, and Reports

Introduction: Oral anticoagulant (OAC) therapy significantly reduces the risk of thromboembolism among at-risk patients with atrial fibrillation (AF). Current guidelines provide strong support for an OAC in men and women with AF and CHA2DS2-VASc scores of >2 and >3, respectively. In spite of this, previous data has suggested that up to 40% of these patients are not treated in accordance with guideline recommendations.

Hypothesis: We hypothesized that OAC therapy continues to remain significantly underutilized among at-risk patients with AF in real-world settings.

Methods: We sought to evaluate the prevalence of OAC underuse and contributing factors in an ambulatory population of …

Abstract 14012: Opportunities To Improve The Efficacy And Safety Of Oral Anticoagulant Therapy In Atrial Fibrillation—Insights From A Multistate Healthcare System, Tyler J Gluckman, Amir Ali, Mansen Wang, Howard Mun, Sally Alfred, John L. Petersen

Articles, Abstracts, and Reports

Introduction: Vitamin K antagonists (VKAs) effectively reduce thromboembolic risk in atrial fibrillation (AF), but are limited by a narrow therapeutic window. Patients with reduced time in the therapeutic range (TTR) also face an increased risk of bleeding and ischemic events. Based in part on this, current guidelines give preference to direct-acting oral anticoagulants (DOACs) over VKAs in AF.

Hypothesis: We hypothesized that DOACs are underutilized among those on oral anticoagulant therapy and that TTR remains suboptimal for large numbers of individuals on VKAs in real-world settings.

Methods: We sought to evaluate a) the breakdown of OAC type and b) TTR …

The Role Of Omega-3 Polyunsaturated Fatty Acids In Blood Pressure Regulation And Secondhand Smoke-Induced Vascular Dysfunction, Emily Anna Wheeler

Biomedical Sciences ETDs

Omega-3 polyunsaturated fatty acids (n-3 PUFAs) may lower cardiovascular disease risk by reducing blood pressure (BP). We hypothesized that fat-1 transgenic mice, which convert n-6 PUFAs to n-3 PUFAs, would have improved vascular function in BP regulation and following secondhand smoke (SHS) exposure, compared to wild type (WT) mice.

BP was recorded in mice fed an n-6 PUFA, or standard chow diet. On the n-6 PUFA diet fat-1 mice had a lower mean arterial pressure and a greater decrease in diastolic BP when treated with an ACE inhibitor, compared to WT mice. No differences were observed on the chow diet. …

Internalized And Anticipated Stigmatization In Patients With Gout, Maria Kleinstäuber, Leonie Wolf, Annie S. K. Jones, Nicola Dalberth, Keith J. Petrie

Psychology Faculty Publications

Objective: To investigate the relationship between stigma perception and demographic, clinical, and psychosocial variables. Methods: A sample of 50 patients with gout and prescribed urate-lowering medication (84% were males, mean serum urate 0.34 mmol/l) completed questionnaires on internalized and anticipated stigma, demographics, clinical gout-related variables, and psychosocial variables (illness perceptions, illness-related disability, illness-related body satisfaction, intentional nonadherence). Serum urate level was obtained from the most recent blood test. Results: In this sample, 26% experienced internalized stigma, 26% expected to be stigmatized by friends or family members, and 14% by health care workers. Univariate regression analyses showed that younger age, ethnicity …

Week Of November 11, 2019, New York Medical College

InTouch

• NYMC Opens Family Health Center to Provide Primary Care to Community, Create Learning Opportunities for Students
• Department of Pediatrics Hosts Ninth Annual Assistant Professor Pediatric Research Symposium
• StuHE Fights Against Breast Cancer

Racism, Bias, And Discrimination As Modifiable Barriers To Breastfeeding For African American Women: A Scoping Review Of The Literature, Karen Marie Robinson, Alissa Fial, Lisa Hanson

College of Nursing Faculty Research and Publications

Introduction

Although breastfeeding has been shown to improve health outcomes for infants, African American women initiate and continue breastfeeding at lower rates than women from other racial groups. This scoping review was conducted to assess the effect racism, bias, and discrimination have on breastfeeding care, support, and outcomes for African American women.

Methods

A scoping review was performed of the literature published between January 2010 through December 2019 using databases MEDLINE via PubMed, CINAHL, Cochrane Library, PsycINFO, and Sociological Abstracts. Studies that examined racism, bias, or discrimination with breastfeeding as an outcome were included. After a review of titles and …

Influence Of Disease Surveillance And Notification Systems On Epidemic Control In Local Government Areas Of Osun State, Michael Segun Omole Dr., Tajudeen Temitayo Adebayo, Rasaq Adetona Adio, Kayode Olayiwola Adepoju, Faruq Abubakar Umar, Micahel Babatunde Adeojo, Aliyu Wada

Library Philosophy and Practice (e-journal)

The study was to contribute to finding solutions to problems associated with disease surveillance and notification systems in relation to epidemic control in local government areas of Osun State.

Survey research design was adopted for the study. The population of the study was three hundred and six (306) medical and health officers in the 30 local government areas of Osun State. Total enumeration technique was used to cover all the 306 health care professionals in the 30 local government areas. A validated questionnaire was used for data collection with response rate of 93.1% and data were analyzed using descriptive …

Information Accessibility And Risk Practices Of People Living With Hiv/Aids In South-West, Nigeria., Tajudeen Temitayo Adebayo, Michael Segun Omole Dr., Muyiwa Adekunle Amin, Adebayo Olawepo Ogunniran

Library Philosophy and Practice (e-journal)

People living with HIV/AIDS (PLWHA) access information from different sources. They are being warned regularly on the need to stay away from all forms of risk practices which may cause further spread of the dreaded diseases. The study endeavour to investigate the level of information access opened to PLWHA and tried to find the relationship between information accessibility and risk practices.

The study adopted survey research design of correlational type. The target population was 8,135PLWHA in the selected three health institutions. Pooled standard error of proportion was used to determine 339 PLWHA and critical incident technique was used to …

Adapting The Diabetes Prevention Program For Low And Middle-Income Countries: Protocol For A Cluster Randomised Trial To Evaluate 'Lifestyle Africa'., Delwyn Catley, Thandi Puoane, Lungiswa Tsolekile, Ken Resnicow, Kandace Fleming, Emily A. Hurley, Joshua M. Smyth, Mara Z. Vitolins, Estelle V. Lambert, Naomi Levitt, Kathy Goggin

Manuscripts, Articles, Book Chapters and Other Papers

Introduction: Low and middle-income countries like South Africa are experiencing major increases in burden of non-communicable diseases such as diabetes and cardiovascular conditions. However, evidence-based interventions to address behavioural factors related to these diseases are lacking. Our study aims to adapt the CDC's National Diabetes Prevention Program (DPP) within the context of an under-resourced urban community in Cape Town, South Africa.

Methods/analysis: The new intervention (Lifestyle Africa) consists of 17 weekly sessions delivered by trained community health workers (CHWs). In addition to educational and cultural adaptations of DPP content, the programme adds novel components of text messaging and …

“We Can Learn Some Things From Them, But They Can Learn Some Things From Us Too”: Intergenerational Perceptions Of Shared Infant Feeding Information, Alexis L. Woods Barr

USF Tampa Graduate Theses and Dissertations

Breastfeeding is associated with unparalleled benefits for infants, mothers, families and society. In light of the breastfeeding disparities and health disparities experienced by the African American community, their women and children stand to gain the most from breastfeeding practices compared to other first-food feeding methods. Moreover, African American mothers are constantly exposed to messages, images, and stereotypes about motherhood (from multiple channels of communication) which influences their infant feeding practices. Many of these exposures send mixed messages and tend to be cultural contradictions of Black motherhood. What complicates this issue is the shortage of research that investigates the intergenerational infant …

“Man Plans But Ultimately, God Decides”: A Phenomenological Investigation Of The Contextual Family Planning Beliefs Of Recently Resettled Congolese Refugee Women In West Central Florida., Linda Bomboka Wilson

USF Tampa Graduate Theses and Dissertations

Existent demographic changes in the United States are largely a result of the current international refugee crisis. Within the past three years, there has been an influx of refugees who were affected by the wars in the Democratic Republic of Congo (DRC). Congolese refugees were the highest number of all refugee groups to arrive in the United States in Fiscal Years 2016-2018, yet little is known about their lived experiences, particularly as they apply to reproductive health and family planning in general. Congolese refugee women who resettle in the United States are unique because many lived in refugee camps for …

Exploration Of Gratitude In Cardiovascular Health: Mediators, Medication Adherence And Psychometrics, Lakeshia A. Cousin

USF Tampa Graduate Theses and Dissertations

The purpose of this dissertation was to explore the effect of gratitude on cardiovascular health outcomes using mediators, medication adherence, and psychometrics. The specific aims were to (1) establish the state of the science for gratitude and cardiovascular health outcomes via a state-of-the-science literature review, (2) explore mediators affecting gratitude and medication adherence using a structural equation model in patients with cardiovascular disease, and (3) analyze the psychometric properties of the Gratitude Questionnaire-6, a self-report questionnaire designed to assess individual differences to express dispositional gratitude, to provide evidence for the validity and reliability of the instrument in African Americans at …

Practice-Based Education Program To Increase Vaccination Rate In Patients On Immunotherapeutic Agents, Andrea M. Soliman Do, Soorya N. Aggarwal Do, Kyle Kreitman Do, Kourtney Erickson Do, Abdul Aleem Md, Marie S. O'Brien Do

Department of Medicine

No abstract provided.

Intraoperative Reboa: An Analysis Of The American Association For The Surgery Of Trauma Aorta Registry., Michael A Vella, Ryan Peter Dumas, Joseph Dubose, Jonathan Morrison, Thomas Scalea, Laura Moore, Jeanette Podbielski, Kenji Inaba, Alice Piccinini, David S Kauvar, Valorie L Baggenstoss, Chance Spalding, Charles Fox, Ernest E Moore, Jeremy W Cannon, Aast Aorta Study Group

Trauma and Acute Care Articles

BACKGROUND: Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a less-invasive technique for aortic occlusion (AO). Commonly performed in the emergency department (ED), the role of intraoperative placement is less defined. We hypothesized that operating room (OR) placement is associated with increased in-hospital mortality.

METHODS: The American Association for the Surgery of Trauma AORTA registry was used to identify patients undergoing REBOA. Injury characteristics and outcomes data were compared between OR and ED groups. The primary outcome was in-hospital mortality; secondary outcomes included total AO time, transfusion requirements, and acute kidney injury.

RESULTS: Location and timing of catheter insertion …

Medical School Watercooler Newsletter - November 10, 2019, Lindsey Lyle

Watercooler Newsletter

This is the November 10, 2019 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

Zha awarded 2019 USA COM Intramural Grant Award

New interest group focuses on military medicine

Networking event to connect female physicians and medical students

Bauer among faculty awarded 2019 intramural grants

USA medical student mentors fellow veteran students

The Role Of Health Information Officers In The Prevention And Management Of Hiv/Aids In Three Tertiary Health Institutions In South Western Nigeria, Tajudeen Temitayo Adebayo

Library Philosophy and Practice (e-journal)

The study was undertaken with the aim of revealing roles of Health Information Officers in the Prevention and Management of HIV/AIDS in Nigeria. The researcher adopted descriptive survey research method in which structured questionnaire was used for data collection in selected three tertiary health institutions. Total enumeration sampling technique was used. The results were presented in frequency tables and percentages.

Role of Health Information Officers which were identify are, generation of useful Information for Prevention of HIV/AIDS, participation in Voluntary Counselling and Testing, promotion of condom usage, preaching of abstinence and faithfulness, educating HIV/positive mothers on the importance of prophylaxis …

Six Month Abstinence Heterogeneity In The Best Quit Study., Harold S Javitz, Terry M Bush, Jennifer C Lovejoy, Alula J Torres, Tallie Wetzel, Ken P Wassum, Marcia M Tan, Nabil Alshurafa, Bonnie Spring

Articles, Abstracts, and Reports

BACKGROUND: Understanding the characteristics of smokers who are successful in quitting may help to increase smoking cessation rates.

PURPOSE: To examine heterogeneity in cessation outcome at 6 months following smoking cessation behavioral counseling with or without weight management counseling.

METHODS: 2,540 smokers were recruited from a large quitline provider and then randomized to receive proactive smoking cessation behavioral counseling without or with two versions of weight management counseling. A Classification and Regression Tree (CART) analysis was conducted to identify the individual pretreatment and treatment characteristics of groups of smokers with different quitting success (as measured by point prevalence of self-reported …

Systemic Toxicity Reported For Cdk8/19 Inhibitors Cct251921 And Msc2530818 Is Not Due To Target Inhibition, Mengqian Chen, Jing Li, Jiaxin Liang, Zanshé S. Thompson, Katie Kathrein, Eugenia Broude, Igor Roninson

Faculty Publications

CDK8/19 kinases, which mediate transcriptional reprogramming, have become an active target for cancer drug discovery. Several small-molecule CDK8/19 inhibitors showed in vivo efficacy and two have entered clinical trials, with no significant toxicities reported. However, Clarke et al. (eLife 2016; 5; e20722) found severe systemic toxicity associated with two potent CDK8/19 inhibitors, Cmpd3 (CCT251921) and Cmpd4 (MSC2530818), and suggested that their toxicity was due to on-target effects. Here, we compared five CDK8/19 inhibitors: Cmpd3, Cmpd4, Senexin B, 16-didehydro-cortistatin A (dCA) and 15w, in different assays. Only Cmpd4 showed striking toxicity in developing zebrafish. In cell-based assays for CDK8 and CDK19 …

Individuals With Recurrent Low Back Pain Exhibit Significant Changes In Paraspinal Muscle Strength After Intramuscular Fine Wire Electrode Insertion, Szu-Ping Lee, Vincent Dinglasan, Anthony Duong, Russell Totten, Jo Armour Smith

Physical Therapy Faculty Articles and Research

Objective

To examine how insertion and presence of intramuscular fine‐wire electromyography electrodes (IFWE) in lumbar multifidus affect paraspinal muscle strength, endurance, and activation in persons with and without recurrent lower back pain (RLBP) during activities that require high levels of muscle contraction.

Design

Case‐control with randomization of conditions.

Setting

Clinical Research Laboratory.

Participants

Forty participants age 18‐40 were recruited (18 female; mean age = 25.5 yr); 20 with a history of RLBP were compared to a matching control group of 20 without RLBP.

Interventions

Each participant was tested under three conditions over three sessions. On Session 1, the baseline condition, …

Evaluating Volatile Organic Compounds For Contact-Independent Antagonism Of Pseudogymnoascus Destructans

Symposium of Student Scholars

White-nose syndrome (WNS), a disease caused by the fungus Pseudogymnoascus destructans, is responsible for the extensive mortality of bats in the United States. In an effort to develop tools to reduce bat mortality attributed to WNS, an in vitro experiment was conducted to quantify the inhibitory effects of select volatile organic compounds (VOCs) as well as explore potential synergistic activities. The experiment involved exposing mycelial plugs of P. destructans to various concentrations of B23 as well as B23 and decanal together at equimolar ratios. Measurements of the plugs were taken over the course of the 13 day experiment allowing …

Preventing Adolescent Dating Violence: An Outcomes Protocol For Evaluating A Gender-Transformative Healthy Relationships Promotion Program, Deinera Exner-Cortens, Alysia Wright, Debb Hurlock, Roseline Carter, Pam Krause, Claire Crooks

Journal Articles

Adolescent dating violence (ADV) is a pressing public health problem in North America. Strategies to prevent perpetration are needed, and a substantial body of research demonstrates the importance of applying a gender lens to target root causes of adolescent dating violence as part of effective prevention. To date, however, there has been limited research on how to specifically engage boys in adolescent dating violence prevention. In this short communication, we describe the protocol for a longitudinal, quasi-experimental outcome evaluation of a program called WiseGuyz. WiseGuyz is a community-facilitated, gender-transformative healthy relationships program for mid-adolescent male-identified youth that aims to reduce …