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2019

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Articles 12991 - 13020 of 16112

Full-Text Articles in Medicine and Health Sciences

Restrictive Ventilatory Patterns In Residents Of Continuing Care Retirement Communities, Christine R. Kovach, Murad H. Taani, Crystal-Rae Waltons, Sheryl Kelber, Irwin Margolis Jan 2019

Restrictive Ventilatory Patterns In Residents Of Continuing Care Retirement Communities, Christine R. Kovach, Murad H. Taani, Crystal-Rae Waltons, Sheryl Kelber, Irwin Margolis

College of Nursing Faculty Research and Publications

Restrictive ventilatory patterns (RVPs) in older adults may contribute to morbidity and decreased quality of life. The purpose of this study was to begin to understand (a) the number of older adults residing in Continuing Care Retirement Communities with RVPs, (b) factors associated with RVP, and (c) whether RVP is associated with ambulation level. This descriptive study was conducted at three sites. RVP was evident in 34 of the 65 participants (52%), and 33 (97%) of these were either moderate or severely restricted. Dementia, dyspnea, kyphosis, and lower muscle strength were significant predictors of RVP. Eighty percent of the nonambulatory …


The Facilitators And Barriers For Active Seniors Attending Physiotherapy, Derek Wood Jan 2019

The Facilitators And Barriers For Active Seniors Attending Physiotherapy, Derek Wood

Theses and Dissertations (Comprehensive)

Physiotherapists are healthcare professionals who can be utilized by the senior population to maintain or improve their health (CPA, 2012). This research examined the experiences of physically active, injured seniors receiving treatment from a physiotherapist in order to understand the barriers and facilitators to treatment and recovery. The study also examined this population’s experiences with physiotherapy (PT) as well as their physical activity (PA) levels and the effect PA had on them.

The study employed a qualitative design which used background questionnaires and semi-structured interviews for data collection. Interviews were transcribed verbatim and thematic analysis was used to analyze the …


Patent Eligibility Of Predictive Algorithm In Second Generation Personalized Medicine, Jerry I-H Hsiao Jan 2019

Patent Eligibility Of Predictive Algorithm In Second Generation Personalized Medicine, Jerry I-H Hsiao

SMU Science and Technology Law Review

No abstract provided.


Safety In Children With Medical Complexity: Our Canaries In The Coal Mine?, Christine A. Schindler, Elisabeth S. Pordes, Steven D. Finkenbinder, K. Jane Lee Jan 2019

Safety In Children With Medical Complexity: Our Canaries In The Coal Mine?, Christine A. Schindler, Elisabeth S. Pordes, Steven D. Finkenbinder, K. Jane Lee

College of Nursing Faculty Research and Publications

Purpose of review

The goal of this paper is to describe the complicated and diverse safety risks facing children with medical complexity.

Recent findings

Children with medical complexity have an increased risk of experiencing adverse health outcomes related to multiple comorbidities, the complicated nature of their care, and frequent interactions with the health care system. The safety risks experienced by children with medical complexity are in large part due to the complex nature of their care rather than the specific risks posed by the complicated nature of their illnesses.

Summary

The complicated nature of care for children with medical complexity …


Factors Affecting Biofilm Formation In Oral Pathogenic Bacteria Of The Red Complex, Sidney Nechacov Jan 2019

Factors Affecting Biofilm Formation In Oral Pathogenic Bacteria Of The Red Complex, Sidney Nechacov

Theses and Dissertations (Comprehensive)

Periodontal disease, also known as periodontitis, is a dental disease that is estimated to affect 2.4 billion people worldwide. This disease is characterized by chronic inflammation and bleeding of gums, as well as loss of tooth bone density. Currently, treatments for the disease include dental surgeries and various types of antibiotics, but few are targeted specifically at the Red Complex bacteria which are strongly associated with chronic periodontitis. The Red Complex consists of three bacteria: Tannerella forsythia, Porphyromonas gingivalis and Treponema denticola. Each of these bacteria, are anaerobic oral pathogens that reside in the subgingival pocket adjacent to …


Optimized Oral Supplementation Of Vitamins Improves Feed Intake And Rumen Microbial Protein Synthesis In Deoni Cows, Ashwin Kandathil, Srinivas Bandla Jan 2019

Optimized Oral Supplementation Of Vitamins Improves Feed Intake And Rumen Microbial Protein Synthesis In Deoni Cows, Ashwin Kandathil, Srinivas Bandla

Turkish Journal of Veterinary & Animal Sciences

The present study was conducted to optimize oral doses of fat- and water-soluble vitamins in cattle using in vitro gas production model and to ascertain their effects on dry matter intake (DMI), nutrient digestibility, and rumen microbial protein (RMBP) synthesis. Doses optimized using the in vitro model were 3.66, 6.78, 16.3, 41.1, 3.87, 0.323, 4.12, and 0.055 mg/kg DMI, respectively, for thiamine, riboflavin, niacin, pantothenic acid, pyridoxine, biotin, folic acid, and B12 and 500 IU/kg DMI for vitamin K. Thirty-two adult, nonproducing Deoni cows (375 ± 13.4 kg body weight, BW) were randomly divided into four equal groups (n = …


Effects Of The Feeds Containing Hazelnut Meal As Plant Protein Source On Growth Performance And Body Composition Of Siberian Sturgeon (Acipenser Baeri) And Economic Profitability Value, Huri̇ye Ariman Karabulut, İlker Zeki̇ Kurtoğlu, Yunus Emre Kirtan Jan 2019

Effects Of The Feeds Containing Hazelnut Meal As Plant Protein Source On Growth Performance And Body Composition Of Siberian Sturgeon (Acipenser Baeri) And Economic Profitability Value, Huri̇ye Ariman Karabulut, İlker Zeki̇ Kurtoğlu, Yunus Emre Kirtan

Turkish Journal of Veterinary & Animal Sciences

In this study, the effects of feeding with the diets containing hazelnut meal (HM) at different levels (0%, 15%, 30%, and 45%) on the growth performance and body composition of Siberian sturgeon were investigated. The study was carried out for 90 days with 3 replicates (n = 15; 283.1 ± 6.52 g fish weight). The highest weight gain (180.62 ± 2.84%) was observed in the control group followed by 15%, 30%, and 45% HM. When the groups were evaluated in terms of SGR, FCR, and PER, the control group was observed to have the best performance. The control group and …


Correlations Between Egg Weight, Early Embryonic Development, And Some Hatching Characteristics Of Japanese Quail (Coturnix Japonica), Beata Grzegrzó?Ka, Joanna Gruszczy?Ska Jan 2019

Correlations Between Egg Weight, Early Embryonic Development, And Some Hatching Characteristics Of Japanese Quail (Coturnix Japonica), Beata Grzegrzó?Ka, Joanna Gruszczy?Ska

Turkish Journal of Veterinary & Animal Sciences

The correlations between selected egg, embryo development, and chick traits were analyzed in three lines of Japanese quail subjected to intrafamily selection for 28th day body weight (group S) and in three lines of random control birds (group K). The significant correlation coefficients between egg weight and most of the traits observed after the first two days of incubation as well as chick weight and shank length were estimated. Most of the correlations obtained were significant in both groups. No statistically significant differences between groups were confirmed, but there was a lines effect within the groups in most cases and …


Methods Of Diagnosis And Treatment Of Postpartum Uterine Infection Adopted By Algerian Veterinarians, Hamza Rahab, Alessandro Ricci, Ahmed Kasseh-Laouar, Christian Hanzen Jan 2019

Methods Of Diagnosis And Treatment Of Postpartum Uterine Infection Adopted By Algerian Veterinarians, Hamza Rahab, Alessandro Ricci, Ahmed Kasseh-Laouar, Christian Hanzen

Turkish Journal of Veterinary & Animal Sciences

The present study aimed to monitor the practices of Algerian veterinarians in the diagnosis and treatment of puerperal metritis (PM) and clinical endometritis (CE) in cattle. For this purpose, a questionnaire was established and distributed to collect the information concerning veterinarian profiles and practices related to the diagnosis and treatment of PM and CE. The results showed that examinations of the uterus (rectal palpation), vaginal discharge, and rectal temperature were the most practiced methods for PM (71%, 68%, and 83%, respectively) and CE (86%, 60%, and 65%, respectively) diagnosis. Tetracycline was the antibiotic of choice for intrauterine treatment of PM …


Ovarian Stimulation Induces High Expression Of Interleukin-1ss And Disrupts The Histological Features Of The Fallopian Tube, Mahmoud Moussa, Sameh Mohamed Farouk Jan 2019

Ovarian Stimulation Induces High Expression Of Interleukin-1ss And Disrupts The Histological Features Of The Fallopian Tube, Mahmoud Moussa, Sameh Mohamed Farouk

Turkish Journal of Veterinary & Animal Sciences

The objective of this study was to investigate whether there is an association between ovarian stimulation and interrupted gamete interaction in the rat fallopian tube in vivo. We evaluated the protein expression of interleukin-1ß (IL-1ß) via immunohistochemistry and assessed the key histological features of the ovaries, fallopian tubes, and uteri of the rats following treatment with mild (15 IU) and high (30 IU) doses of gonadotropins compared to an unstimulated control group. The serum concentration of estradiol was also determined by immunoassay. The results revealed that high levels of circulating estrogen were associated with higher expression of the IL-1ß protein …


Assessment Of Asymmetric Dimethyl Arginine, Cardiac Troponin I, Thyroxine, Cholesterol, And Triglyceride Levels In Obese Dogs And Dogs With Normal Body Condition, Hüseyi̇n Ci̇han, Merve Tural Jan 2019

Assessment Of Asymmetric Dimethyl Arginine, Cardiac Troponin I, Thyroxine, Cholesterol, And Triglyceride Levels In Obese Dogs And Dogs With Normal Body Condition, Hüseyi̇n Ci̇han, Merve Tural

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to assess serum asymmetric dimethyl arginine (ADMA), cardiac troponin I (cTnI), thyroxine (T4), cholesterol and triglyceride (TG) levels in dogs with normal body condition and obese dogs. A total of 40 dogs (n = 40) were included in the study and dogs were divided into two groups; 20 dogs with normal body condition and 20 obese dogs. The dogs were grouped according to the five-point body-condition scoring (BCS) system. Serum ADMA, cTnI, T4, cholesterol, and TG levels were measured in addition to routine biochemical parameters. Serum ADMA, cTnI, TG, and cholesterol levels were statistically …


Electrocardiogram And Serum Cardiac Biomarkers Changes In Fmd In Cattle, Ali Abbas Nikvand, Seyedeh Missagh Jalali, Mohammad Nouri, Alireza Ghadrdan Mashhadi, Soroush Hassanpour Amirabadi Jan 2019

Electrocardiogram And Serum Cardiac Biomarkers Changes In Fmd In Cattle, Ali Abbas Nikvand, Seyedeh Missagh Jalali, Mohammad Nouri, Alireza Ghadrdan Mashhadi, Soroush Hassanpour Amirabadi

Turkish Journal of Veterinary & Animal Sciences

This study was designed to evaluate serum and electrocardiographic (ECG) changes in cattle with foot-and-mouth disease (FMD). Thirty-two cows with clinical signs of FMD and 13 healthy cows were randomly enrolled. After blood sampling, ECG was performed on 23 of the 32 ill cows. Serum circulatory troponin I (cTnI), CPK, LDH, and CK-MB activities were determined in the patient and control groups. Arrhythmias including ventricular tachycardia (VT), sinus tachycardia (ST), atrial fibrillation (AF), and premature ventricular complex (PVC) were seen in 4, 4, 2, and 1 of the patients, respectively. The patients had higher cTnI levels than the control group …


Accumulation And Histological Transformation In The Gills, Liver, Muscles, And Skin In Oreochromis Niloticus Induced By Mercury, Khalid Abdullah Al-Ghanim, Zubair Ahmad, Hmoud Fares Alkahem Al-Balawi, Fahad Al-Misned, Shahid Mahboob, El Amin Mohammad Suliman Jan 2019

Accumulation And Histological Transformation In The Gills, Liver, Muscles, And Skin In Oreochromis Niloticus Induced By Mercury, Khalid Abdullah Al-Ghanim, Zubair Ahmad, Hmoud Fares Alkahem Al-Balawi, Fahad Al-Misned, Shahid Mahboob, El Amin Mohammad Suliman

Turkish Journal of Veterinary & Animal Sciences

Specimens of Oreochromis niloticus (One control and 3 experimental groups) were fed diets mixed with different doses of mercury (control group = free of mercury; group 1 = 500 mg/kg; group 2 = 750 mg/kg, and group 3 = 1000 mg/kg) for 60 days in order to study its accumulation and histopathological alterations in the liver, gills, skeletal muscles, and skin. The results obtained revealed that mercury accumulation was significantly (P < 0.05) high in the liver and gills compared to the muscles and skin. The order of accumulation in these organs revealed to be liver > gills > muscles > skin. The fish fed various doses of mercury also showed histological alterations in these organs. Epithelial lifting and epithelial hypertrophy were seen in the gills of the …


Evaluation Of Milk Glutathione Peroxidase And Superoxide Dismutase Levels In Subclinical Mastitis In Damascus Goats, İsfendi̇yar Darbaz, Seçki̇n Salar, Serkan Sayiner, İdi̇l Baştan, Osman Ergene, Ayhan Baştan Jan 2019

Evaluation Of Milk Glutathione Peroxidase And Superoxide Dismutase Levels In Subclinical Mastitis In Damascus Goats, İsfendi̇yar Darbaz, Seçki̇n Salar, Serkan Sayiner, İdi̇l Baştan, Osman Ergene, Ayhan Baştan

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to evaluate milk glutathione peroxidase (GPx) and superoxide dismutase (SOD) levels in Damascus goats with subclinical mastitis. According to the somatic cell counts (SCCs), 193 Damascus goats included in the study were divided into healthy (n = 75; SCC 0.05). In summary, a significant increase in GPx and decrease in SOD levels, respectively, were determined in goat milk samples with subclinical mastitis, and these changing trends were correlated with milk SCCs. However, age, parity, and number of offspring were not associated with these changing patterns.


Proliferation Effects Of Phenylboronic Acid And Boric Acid On Canine Peripheral Blood Mononuclear Cells, Uçkun Sai̇t Uçan, Zafer Sayin Jan 2019

Proliferation Effects Of Phenylboronic Acid And Boric Acid On Canine Peripheral Blood Mononuclear Cells, Uçkun Sai̇t Uçan, Zafer Sayin

Turkish Journal of Veterinary & Animal Sciences

The effects of phenylboronic acid (PBA) and boric acid (BA) on the proliferation of canine peripheral blood mononuclear cells (PBMCs) were investigated. Treatment of PBMCs from mixed breed dogs with PBA or BA (0.05 µg/mL) alone elicited blastogenic responses of 0.478 ± 0.438 and 0.499 ± 0.366, respectively. We observed an additive effect on proliferation when purebred Kangal PBMCs were cultured in a combination of BA (0.001 µg/mL) and the mitogenic lectin concanavalin A (1 µg/mL). However, the effects were not statistically significant. We detected varied IL-2 and IL-4 secretion in response to stimulation with boron-containing compounds. Our findings suggest …


Prolonged Gestation In A Swedish Red Cow Due To Fetal Unilateral Adrenal Gland Dysgenesis, Ebru Karakaya-Bi̇len, Ahmet Akkoç, Bariş Güner, Gülnaz Yilmazbaş-Meci̇toğlu, Ahmet Gümen, Abdulkadi̇r Keski̇n Jan 2019

Prolonged Gestation In A Swedish Red Cow Due To Fetal Unilateral Adrenal Gland Dysgenesis, Ebru Karakaya-Bi̇len, Ahmet Akkoç, Bariş Güner, Gülnaz Yilmazbaş-Meci̇toğlu, Ahmet Gümen, Abdulkadi̇r Keski̇n

Turkish Journal of Veterinary & Animal Sciences

A 5-year-old Swedish Red cow, pregnant for 465 days according to the last insemination record, was presented in this case. She conceived by artificial insemination at spontaneous estrus using frozen-thawed sperm of Swedish Red sire. No abnormalities were detected during gestation and no clinical signs of parturition at the expected time of delivery were noted. She was reexamined several times to eliminate breeding records error and, once prolonged gestation was confirmed, parturition was induced. The calf survived birth but died 10 min after birth. A macroscopically giant fetus was diagnosed. Following necropsy, some congenital anomalies were noticed. While the structure …


Comparisons Of Some Physiological And Stress Behavioral Parameters Of Kangal Shepherd Dogs With And Without Ankyloglossia In Different Environmental Temperatures, Mustafa Koçkaya, Yusuf Özşensoy, Burcu İnsal Jan 2019

Comparisons Of Some Physiological And Stress Behavioral Parameters Of Kangal Shepherd Dogs With And Without Ankyloglossia In Different Environmental Temperatures, Mustafa Koçkaya, Yusuf Özşensoy, Burcu İnsal

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to compare Kangal shepherd dogs with and without ankyloglossia in terms of various physiological and behavioral changes. A total of 24 dogs were used, 11 of which have had ankyloglossia and 13 of which did not have ankyloglossia. Heart rates, respiratory rates, and body temperatures of the dogs were measured at three different environmental temperatures (18, 23, and 28 °C), resting state, and different exercise durations (5, 10, and 15 min). In addition, resting state and some behavioral parameters were recorded with a video camera. Mann?Whitney U, Kruskal-Wallis, and Wilcoxon tests were used to …


Morphological And Carcass Traits Of Three Chicken Genotypes Under Free-Range, Semiintensive, And Intensive Housing Systems, Sohail Ahmad, Athar Mahmud, Jibran Hussain, Khalid Javed Jan 2019

Morphological And Carcass Traits Of Three Chicken Genotypes Under Free-Range, Semiintensive, And Intensive Housing Systems, Sohail Ahmad, Athar Mahmud, Jibran Hussain, Khalid Javed

Turkish Journal of Veterinary & Animal Sciences

The present study evaluated the effect of housing system on morphometric and carcass traits of 3 chicken genotypes. In total, 180 cockerels and 180 pullets of 6 weeks old were studied. A randomized complete block design in factorial arrangement, with 18 experimental units of 20 birds each, was applied. Treatments consisted of 3 genotypes consisting of purebred Naked Neck (NN) birds and two crossbreeds (Rhode Island Red × Naked Neck = RNN, Black Australorp × Naked Neck = BNN) and 3 housing systems (free-range, semiintensive, and intensive). Regarding males, RNN chickens had the highest weight at slaughter (1491.12 ± 64.10 …


Effects Of The Inclusion Of Detoxified Argan Press Cake In The Diet Of Dairy Goats On Milk Production And Milk Quality, Nazha Lakram, Sana Moutik, Ikram Mercha, El Haj El Maadoudi, Rachid Kabbour, Ahmed Douaik, Abdelmajid Zouahri, Abdelah El Housni, Mariam Naciri Jan 2019

Effects Of The Inclusion Of Detoxified Argan Press Cake In The Diet Of Dairy Goats On Milk Production And Milk Quality, Nazha Lakram, Sana Moutik, Ikram Mercha, El Haj El Maadoudi, Rachid Kabbour, Ahmed Douaik, Abdelmajid Zouahri, Abdelah El Housni, Mariam Naciri

Turkish Journal of Veterinary & Animal Sciences

This study was carried out to assess the effect of the incorporation of detoxified argan press cake on milk yield, physicochemical composition, and microbial quality of raw Alpine goat milk produced in the Meskala-Essaouira region of southwestern Morocco. The detoxification method, adopted for the removal of saponin present in the argan press cake, succeeded in reducing these antinutrients from 4.56 to 0.4 mg/g, allowing it to be used as livestock feed. The average of milk production increased by 24% for the detoxified argan press cake (DAPC) group compared to the argan press cake and local diet groups. The diets and …


Leptin Supplementation In Embryo Culture Medium Increases In Vivo Implantation Rates In Mice, Ali̇ Ci̇han Taşkin, Ahmet Kocabay Jan 2019

Leptin Supplementation In Embryo Culture Medium Increases In Vivo Implantation Rates In Mice, Ali̇ Ci̇han Taşkin, Ahmet Kocabay

Turkish Journal of Veterinary & Animal Sciences

Leptin is a hormone-like protein consisting of 167 amino acids. The aim of this study is to compare the effects of different leptin concentrations on in vitro and in vivo embryo development rates. In vitro development rates were investigated by embryo culture studies, and in vivo implantation rates and the quality of embryos were assessed by embryo transfers to the recipient mice. The results showed that addition of leptin into the embryo culture medium at 10 and 100 ng/mL doses supported the in vitro development of mouse embryo. Moreover, leptin increased the total cell number of blastocyst, particularly the trophectoderm …


Deviations Of Feedstuffs Loading In Tmr Preparation, Seli̇m Sirakaya, Osman Küçük Jan 2019

Deviations Of Feedstuffs Loading In Tmr Preparation, Seli̇m Sirakaya, Osman Küçük

Turkish Journal of Veterinary & Animal Sciences

Loading of feedstuffs in planned amounts in total mixed ration (TMR) recipes are very important in terms of profitability, productivity, animal health, and performance. In the scope of this study, the planned and loaded feedstuffs amounts were determined in the mixer wagons. The study was conducted on a dairy cattle farm with ~1500 milking cow capacity. In this study, 13,276 feedstuffs loading data were examined and the mean and standard deviation of the deviation from the planned amount was 8.95 ± 18.38%. Deviation values of feedstuffs loading were found to be different; according to 1- TMR preparing operators, 2- type …


Anesthetic And Sedative Efficacy Of Peppermint (Mentha Piperita) And Lavender (Lavandula Angustifolia) Essential Oils In Blue Dolphin Cichlid (Cyrtocara Moorii), Erkan Can, Esma Sümer Jan 2019

Anesthetic And Sedative Efficacy Of Peppermint (Mentha Piperita) And Lavender (Lavandula Angustifolia) Essential Oils In Blue Dolphin Cichlid (Cyrtocara Moorii), Erkan Can, Esma Sümer

Turkish Journal of Veterinary & Animal Sciences

The use of different essential oils (Eo$_{s}$), which are considered as a good alternative to synthetic materials, is increasing day by day in fish species. Nevertheless, studies on the anesthetic effect of peppermint Eo (Mentha piperita; MPEo) and lavender Eo (Lavandula angustifolia; LAEo) are scarce. In the present study, the effective concentrations of three anesthetic materials (MPEo, LAEo, and MS-222) were previously determined in the concentrations range of 100-400 ppm in Cyrtocara moorii juveniles (4.92 ± 1.03 g and 7.13 ± 1.22 cm) with the criteria of appropriate induction time (AI$_{t}$) and ready recovery time (RRt) (Trial 1). Afterwards, four …


Genetic Analysis Of Iranian Mycoplasma Gallisepticum Isolates Using Gene-Targeted Sequencing Of Complete Pvpa Gene, Naghmeh Kabiri, Mohsen Bashashati, Mehdi Vasfi Marandi, Mansour Banani, Fereshteh Sabouri Jan 2019

Genetic Analysis Of Iranian Mycoplasma Gallisepticum Isolates Using Gene-Targeted Sequencing Of Complete Pvpa Gene, Naghmeh Kabiri, Mohsen Bashashati, Mehdi Vasfi Marandi, Mansour Banani, Fereshteh Sabouri

Turkish Journal of Veterinary & Animal Sciences

This study aims to evaluate Mycoplasma gallisepticum (MG) genetic diversity through the complete sequencing of the pvpA gene among six MG isolates present in industrial poultry from 2015 to 2016. The genetic comparison of these six isolates showed similarities of over 94% and 92% in terms of nucleotide and amino acid sequences, respectively. The size of the PvpA protein in the studied isolates included three different sizes with 361, 364, and 366 amino acids. The carboxy-terminus of the studied PvpA proteins contained 11 tetrapeptides of P-R-P-M/Q/N motifs with truncation in the proline-rich region. Based on the BLAST analysis, the pvpA …


Isolation And Molecular Characterization Of Salmonella Enterica And Escherichia Coli From Poultry Samples, Ayli̇n Cesur, Saci̇de Özlem Ulutaş, Yeşi̇m Soyer Jan 2019

Isolation And Molecular Characterization Of Salmonella Enterica And Escherichia Coli From Poultry Samples, Ayli̇n Cesur, Saci̇de Özlem Ulutaş, Yeşi̇m Soyer

Turkish Journal of Veterinary & Animal Sciences

Innumerable foodborne pathogens including Salmonella and Escherichia coli pose a serious threat to human health and food safety. As perishable foods, poultry products are considered one of the most common sources of foodborne pathogens including Salmonella and E. coli due to transmission of drug resistance, dissemination of organisms, and cross-contamination. In our study, phenotypic and genotypic characterizations of Salmonella enterica and E. coli isolated from packaged raw chicken products were carried out. Samples belonging to different commercial brands were collected in Ankara in 2015. Among 15 out of 19 Salmonella enterica subsp. enterica strains isolated from different and/or same poultry …


Drug Repositioning Based On Bounded Nuclear Norm Regularization, Mengyun Yang, Huimin Lao, Yaohang Li, Jianxin Wang Jan 2019

Drug Repositioning Based On Bounded Nuclear Norm Regularization, Mengyun Yang, Huimin Lao, Yaohang Li, Jianxin Wang

Computer Science Faculty Publications

Motivation: Computational drug repositioning is a cost-effective strategy to identify novel indications for existing drugs. Drug repositioning is often modeled as a recommendation system problem. Taking advantage of the known drug–disease associations, the objective of the recommendation system is to identify new treatments by filling out the unknown entries in the drug–disease association matrix, which is known as matrix completion. Underpinned by the fact that common molecular pathways contribute to many different diseases, the recommendation system assumes that the underlying latent factors determining drug–disease associations are highly correlated. In other words, the drug–disease matrix to be completed is low-rank. Accordingly, …


Biomaterials Evaluation: Conceptual Refinements And Practical Reforms, Reza Masaeli, Kavosh Zandsalimi, Lobat Tayebi Jan 2019

Biomaterials Evaluation: Conceptual Refinements And Practical Reforms, Reza Masaeli, Kavosh Zandsalimi, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Regarding the widespread and ever-increasing applications of biomaterials in different medical fields, their accurate assessment is of great importance. Hence the safety and efficacy of biomaterials is confirmed only through the evaluation process, the way it is done has direct effects on public health. Although every biomaterial undergoes rigorous premarket evaluation, the regulatory agencies receive a considerable number of complications and adverse event reports annually. The main factors that challenge the process of biomaterials evaluation are dissimilar regulations, asynchrony of biomaterials evaluation and biomaterials development, inherent biases of postmarketing data, and cost and timing issues. Several pieces of evidence indicate …


Culture Of Dental Pulp Stem Cells On Nanoporous Alumina Substrates Modified By Carbon Nanotubes, Ameneh Alizadeh, Amir Razmjou, Mehrorang Ghaedi, Ramin Jannesar, Fahimeh Tabatabaei, Vahid Pezeshkpour, Lobat Tayebi Jan 2019

Culture Of Dental Pulp Stem Cells On Nanoporous Alumina Substrates Modified By Carbon Nanotubes, Ameneh Alizadeh, Amir Razmjou, Mehrorang Ghaedi, Ramin Jannesar, Fahimeh Tabatabaei, Vahid Pezeshkpour, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Purpose: Alumina substrates are one of the commonly used scaffolds applied in cell culture, but in order to prevent formation of biofilm on the alumina substrate, these substrates are modified with carbon nanotube. Methods: The alumina substrate was made by a two-step anodization method and was then modified with carbon nanotubes by simple chemical reaction. The substrates were characterized with FTIR, SEM, EDX, 3D laser scanning digital microscope, contact angle (CA) and surface free energy (SFE). To determine how this modification influences the reduction of biofilm, biofilm of two various bacteria, Escherichia coli (E.coli) and Staphylococcus aureus ( …


Applications Of 3d Printing On Craniofacial Bone Repair: A Systematic Review, Michael Maroulakos, George Kamperos, Lobat Tayebi, Demetrios J. Halazonetis, Yijin Ren Jan 2019

Applications Of 3d Printing On Craniofacial Bone Repair: A Systematic Review, Michael Maroulakos, George Kamperos, Lobat Tayebi, Demetrios J. Halazonetis, Yijin Ren

School of Dentistry Faculty Research and Publications

Objectives

Three-dimensional (3D) bioprinting, a method derived from additive manufacturing technology, is a recent and ongoing trend for the construction of 3D volumetric structures. The purpose of this systematic review is to summarize evidence from existing human and animal studies assessing the application of 3D printing on bone repair and regeneration in the craniofacial region.

Data & sources

A rigorous search of all relevant clinical trials and case series was performed, based on specific inclusion and exclusion criteria. The search was conducted in all available electronic databases and sources, supplemented by a manual search, in December 2017.

Study selection

43 …


Ankylosing Spondylitis And Mesenchymal Stromal/Stem Cell Therapy: A New Therapeutic Approach, Kamal Abdolmohammadi, Fatemeh Dadgar Pakdel, Hamideh Aghaei, Sara Assadiasl, Yousef Fatahi, Negin Hosseini Rouzbahani, Alireza Rezaiemanesh, Masoud Soleimani, Lobat Tayebi, Mohammad Hossein Nicknam Jan 2019

Ankylosing Spondylitis And Mesenchymal Stromal/Stem Cell Therapy: A New Therapeutic Approach, Kamal Abdolmohammadi, Fatemeh Dadgar Pakdel, Hamideh Aghaei, Sara Assadiasl, Yousef Fatahi, Negin Hosseini Rouzbahani, Alireza Rezaiemanesh, Masoud Soleimani, Lobat Tayebi, Mohammad Hossein Nicknam

School of Dentistry Faculty Research and Publications

Ankylosing spondylitis (AS) is an inflammatory rheumatoid disease categorized within spondyloarthropathies (SpA) and manifested by chronic spinal arthritis. Several innate and adaptive immune cells and secreted-mediators have been indicated to play a role in AS pathogenesis. Considering the limitations of current therapeutic approaches (NSAIDs, glucocorticoids, DMARDs and biologic drugs), finding new treatments with fewer side effects and high therapeutic potentials are required in AS. Mesenchymal stem cells (MSCs) with considerable immunomodulatory and regenerative properties could be able to attenuate the inflammatory responses and help tissue repair by cell-to-cell contact and secretion of soluble factors. Moreover, MSCs do not express HLA-DR, …


Long-Term Clinical Results Of Intra-Articular Injections For Osteoarthritis Of The Knee, Michael Swartzon, Andre Anderson, Luis Rodriguez Jan 2019

Long-Term Clinical Results Of Intra-Articular Injections For Osteoarthritis Of The Knee, Michael Swartzon, Andre Anderson, Luis Rodriguez

All Publications

No abstract provided.