Medicine and Health Sciences Commons^™

Myocardial Perfusion Imaging: The Gatekeeper And Advisor, Maseeh Uz Zaman, Nosheen Fatima

Department of Radiology

No abstract provided.

Inspire : Vol 1, Issue 2, Department Of Medicine

INSPIRE – Department of Medicine Archives

Content

• Hepatitis c test changed my life
• Dermatology faculty extending the footprint of Dept. of Medicine at various National and International Forums
• The regional impact of Auk's training program; a reflection from a former fellow, Dr Shereen khan fops', maps.
• Promotion; Dr. Faisal Ismail
• Dermatology faculty extending the footprint of Dept. of Medicine at various National and International Forums
• Dr. Yawer Saeed; The new Cardiologist/Poet on the Dom block

Cime Newsletter : March 2018, Cime

Centre for Innovation in Medical Education (CIME) Archives

- SONAM Skills Lab becomes Part of CIME

- Critial Care Nursing (CCN) Simulation Workshop for BScN Students

- 5th CEEA CME Course

- 3rd Annual Surgical Meeting

- Neurovascular Course @ CIME

- Postgraduate Medical Education Conference

- An Interview with the Crocodile

- CIME Video: Exploring The Human Patient Simulator

- Publication by Faculty

Role Of Interventional Radiology In The Management Of Peripheral Vascular Malformations: A Tertiary Care Center Experience., Misbah Tahir, Muhammad Anees Mumtaz, Anum Sultan, Raza Sayani

Department of Radiology

Peripheral vascular malformations (PVMs) represent a wide spectrum of vascular abnormalities occurring due to anomalous connections between arteries, veins, capillaries, and lymphatic channels at the microscopic level, in different combinations. They are rare and challenging to treat. Different operators may have different approaches based on their experience and expertise. Sclerotherapy either alone or in combination with embolization has been used as an independent method for the treatment of PVMs. Purpose The aim of this study is to assess the safety and efficacy of sclerotherapy and embolization, with or without surgery, for the treatment of peripheral vascular malformations, based on our …

Integrating Nutrition Into Health Systems At Community Level:Impact Evaluation Of The Community‐Based Maternal Andneonatal Health And Nutrition Projects In Ethiopia, Kenya, And Senegal, Jacqueline K. Kung'u, Richard Pendame, Mame Bineta Ndiaye, Mulusew Gerbaba, Sophie Ochola, Adama Faye, Sulochana Basnet, Edward A. Frongillo Jr., Sara Wuehler, Luz Maria De‐Regil

Faculty Publications

Maternal undernutrition and mortality remain high in several African countries. Key nutrition andhealth interventions improve maternal and birth outcomes. Evidence is scarce on how tostrengthen health systems to ensure pregnant women and newborns are reached with theseinterventions. We conducted three quasi‐experimental nonrandomized Community BasedMaternal and Neonatal Health and Nutrition projects in regions of Ethiopia, Senegal, and Kenyato demonstrate how proven nutrition interventions could be integrated into health programs toimprove knowledge and practices during pregnancy, birth, and postpartum. We evaluated impacton knowledge and practices related to maternal and neonatal care using logistic regression andrepeated‐measures models with districts as a fixed variable …

Assembly And Analysis Of A Qingke Reference Genome Demonstrate Its Close Genetic Relation To Modern Cultivated Barley, Fei Dai, Xiaolei Wang, Xiao-Qi Zhang, Zhonghua Chen, Eviatar Nevo, Gulei Jin, Dezhi Wu, Chengdao Li, Guoping Zhang

Publications

Qingke, the local name of hulless barley in the Tibetan Plateau, is a staple food for Tibetans. The availability of its reference genome sequences could be useful for studies on breeding and molecular evolution. Taking advantage of the third-generation sequencer (PacBio), we de novo assembled a 4.84-Gb genome sequence of qingke, cv. Zangqing320 and anchored a 4.59-Gb sequence to seven chromosomes. Of the 46,787 annotated 'high-confidence' genes, 31 564 were validated by RNA-sequencing data of 39 wild and cultivated barley genotypes with wide genetic diversity, and the results were also confirmed by nonredundant protein database from NCBI. As some gaps …

Comparative Analysis Of Microbial Sensing Molecules In Mucosal Tissues With Aging, Octavio A. Gonzalez, Sreenatha S. Kirakodu, Michael John Novak, A. J. Stromberg, L. Orraca, J. Gonzalez-Martinez, A. Burgos, Jeffrey L. Ebersole

Center for Oral Health Research Faculty Publications

Host-bacterial interactions at mucosal surfaces require recognition of the bacteria by host cells enabling targeted responses to maintain tissue homeostasis. It is now well recognized that an array of host-derived pattern recognition receptors (PRRs), both cell-bound and soluble, are critical to innate immune engagement of microbes via microbial-associated molecular patterns (MAMP). This report describes the use of a nonhuman primate model to evaluate changes in the expression of these sensing molecules related to aging in healthy gingival tissues. Macaca mulatta aged 3-24 years were evaluated clinically and gingival tissues obtained, RNA isolated and microarray analysis conducted for gene expression of …

A Comparison Of Oral And Intravenous Mouse Models Of Listeriosis, Michelle G. Pitts, Sarah E. F. D'Orazio

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Listeria monocytogenes is one of several enteric microbes that is acquired orally, invades the gastric mucosa, and then disseminates to peripheral tissues to cause systemic disease in humans. Intravenous (i.v.) inoculation of mice with L. monocytogenes has been the most widely-used small animal model of listeriosis over the past few decades. The infection is highly reproducible and has been invaluable in deciphering mechanisms of adaptive immunity in vivo, particularly CD8+ T cell responses to intracellular pathogens. However, the i.v. model completely bypasses the gut phase of the infection. Recent advances in generating both humanized mice and murinized bacteria, as well …

Oncolog, Volume 63, Number 03, March 2018, Bryan Tutt

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Local Consolidative Therapy Plus Immunotherapy or Targeted Agents for NSCLC: Clinical trials explore surgery/radiation plus immune checkpoint or tyrosine kinase inhibitors for metastatic non-small cell lung cancer
• INBRIEF: CAR T Cells Elicit Durable Responses in Large B Cell Lymphoma
• Managing Opioid Use in Cancer Patients: Vigilance and interventions ensure patient safety
• Hepatitis C Virus Linked to Head and Neck Cancers: Association of HCV with extrahepatic cancers has implications for HCV testing, treatment
• HOUSE CALL: Understanding cancer Risk and Risk factors-Your risk factors might affect your need for cancer screening

Promotion Of Lactobacillus Plantarum On Growth And Resistance Against Acute Hepatopancreatic Necrosis Disease Pathogens In White-Leg Shrimp (Litopenaeus Vannamei), Thi Thuy Giang Nguyen, Thi Chinh Nguyen, Montira Leelakriangsak, Thu Thuy Pham, Quoc Hung Pham, Chokchai Lueangthuwapranit, Van Duy Nguyen

The Thai Journal of Veterinary Medicine

Acute hepatopancreatic necrosis disease (AHPND), or early mortality syndrome (EMS), causes high mortality in cultivated penaeid shrimps, which leads to heavy losses for shrimp farming industry. V. parahaemolyticus with a toxin PirAB-encoding extrachromosomal plasmid are considered as common pathogenic agents. The present study aimed to assess the effects of potential probiotics on growth and resistance of shrimp to AHPND infection. Results confirmed typical clinical signs and histopathological features in AHPND-infected shrimps. Among 11 Vibrio isolates from AHPND-infected shrimps, strain XN9 was the most virulent and was identified as V. paraheamolyticus using AP3-based PCR amplification and API 20E kits. In vitro …

Treatment Of Glenohumeral Arthritis Pain Utilizing Spinal Cord Stimulation., Stephen T Susa, Chris S Karas, Nathaniel K Long

Neuroscience Articles

BACKGROUND: Dorsal column stimulation may be utilized to treat non-neuropathic pain attributed to glenohumeral arthritis.

CASE DESCRIPTION: An 84-year-old female presented with right shoulder pain for 3 years. She was diagnosed with glenohumeral arthritis and a complete loss of the joint space. She was treated with a dorsal column stimulator, requiring the electrodes to be placed from the inferior aspect of C3 to the superior aspect of T1. Six weeks postoperatively, she reported >90% coverage of her shoulder pain, demonstrated increased right arm function, and a reduction in her use of narcotics.

CONCLUSION: Dorsal column stimulation of C3-T1 proved to …

Comparison Of Disease-Modifying Therapies For The Management Of Multiple Sclerosis: Analysis Of Healthcare Resource Utilization And Relapse Rates From Us Insurance Claims Data., Jacqueline Nicholas, Aaron Boster, Ning Wu, Wei-Shi Yeh, Monica Fay, Jon Kendter, Ming-Yi Huang, Andrew Lee

Neuroscience Articles

BACKGROUND: Data on comparative healthcare resource utilization and costs associated with the newer oral disease-modifying therapies (DMTs) for managing relapsing-remitting multiple sclerosis (MS) in routine clinical practice are limited. The purpose of this study was to estimate healthcare resource utilization, costs, and relapse rates in the year after initiating treatment with dimethyl fumarate (DMF), interferon (IFN)-β, glatiramer acetate (GA), teriflunomide, or fingolimod in routine clinical practice for patients with MS who did not receive a DMT in the previous year.

METHODS: Patients initiating DMF, IFNβ, GA, teriflunomide, or fingolimod were identified based on claims data from 2012 to 2015 in …

Intraoperative Femoral Head Dislodgement During Total Hip Arthroplasty: A Report Of Four Cases, Ahmed Siddiqi, Carl T. Talmo, James V. Bono

Orthopedic Surgery Resident Research

Dislodgment of trial femoral heads and migration into the pelvis during total hip arthroplasty is a rarely reported complication with limited published cases. There are three primary mechanisms of femoral head separation: dislodgement during reduction attempt, disassociation from anterior dislocation while assessing anterior stability, and during dislocation after implant trialing. If the trial femoral migrates beyond the pelvic brim, it is safer to finish the total hip arthroplasty and address the retained object after repositioning or in a planned second procedure with a general surgeon. We recommend operative retrieval since long-term complications from retention or clinical results are lacking.

Invisible No More: Bringing Awareness To Mental Health In Older Adults Living In Rural Minnesota, Abigail Schaper, Carley Ledoux, Kristry Danielson

Master of Social Work Student Policy Advocacy Briefs

Approximately 8 million Americans 65 years of age and older have mental health disorders. It is estimated that these numbers could reach 14.4 million by 2030. Minnesotans turning 65 in this decade (about 285,000) will be greater than the past four decades combined (Aging: MN State Demographic Center, 2018). Anxiety and depression are two of the more common mental health disorders in older adults and are associated with severe consequences, including life dissatisfaction, illness, and mortality. With this growth comes many barriers. The rural mental health system is not equipped to address this growth. The system is underfunded, largely uncoordinated, …

Launch-Ing Minnesota Early Childhood Mental Health Into The Future, Molly Abdo, Alyssa Baker, Elizabeth Holz

Master of Social Work Student Policy Advocacy Briefs

What is Social-Emotional Development? The foundation for lifelong mental health, including social and emotional development, is established early in life and shaped by children's relationships with parents, caregivers, and peers. This foundation is critical to all aspects of healthy development and growth in early childhood. Social-emotional development can be defined as "the capacity to form secure relationships; experience, express, and manage a range of emotions; and learn and explore one's environment."

Why is it Important? When children fail to develop social-emotionally, mental health symptoms begin to emerge and can "cause distress, interfere with relationships, limit the child's participation in daily …

The Social Isolation Epidemic: A Public Health Concern, Jolynne Bockman, Allison Frandrup, Hannah Miner

Master of Social Work Student Policy Advocacy Briefs

Social isolation kills. Loneliness and social isolation raise the likelihood of coronary heart disease and stroke, result in poor cardiovascular and mental health outcomes, and drastically increase the likelihood of death. Resulting health implications that stem from real or perceived physical or emotional remoteness include a spectrum of harsh realities ranging from feelings of low self-worth to reduced work capacity to attempts to harm oneself. Social isolation does not have to become the defining reality of modern life. Attention to the vast loneliness spreading through diverse populations across the state is desperately needed as a means to combat this modern …

Outcomes Of Catheter Ablation For Supraventricular Tachycardia In Adult Patients With Congenital Heart Disease, Lohit Garg Md, Sahil Agrawal Md, Manyoo Agarwal Md, Brijesh Patel Md, Mahek Shah Md, Aakash Garg Md, Sudip Nanda Md, Facp, Talha Nazir Md, Raman Dusaj Md

Department of Medicine

Background: Supraventricular tachyarrhythmias (SVT) are common in adult patients with congenital heart disease (CHD). There is paucity of data regarding the safety and outcomes associated with catheter ablation in these patients.

Methods: We queried the National Inpatient Sample (NIS) to identify all adults patients > 18 years with CHD undergoing catheter ablation for SVT.

Results: Between 2003-2013, 5,966 patients with CHD underwent catheter ablation for SVT. Of these 4,769 were performed for atrial fibrillation or atrial flutter and rest for other SVTs. The mean age of these patient was 47+/- 15 years, 59.9% were males. 18% of patients experienced procedure related …

A Spline-Assisted Semiparametric Approach To Nonparametric Measurement Error Models, Fei Jiang, Yanyuan Ma

COBRA Preprint Series

Nonparametric estimation of the probability density function of a random variable measured with error is considered to be a difficult problem, in the sense that depending on the measurement error prop- erty, the estimation rate can be as slow as the logarithm of the sample size. Likewise, nonparametric estimation of the regression function with errors in the covariate suffers the same possibly slow rate. The traditional methods for both problems are based on deconvolution, where the slow convergence rate is caused by the quick convergence to zero of the Fourier transform of the measurement error density, which, unfortunately, appears in …

Metastatic Cancers Treated With Concurrent Pd-1 Inhibition And Stereotactic Ablative Radiotherapy (Sabr), Jason Naziri Bs, Samuel Adediran Md, Suresh G. Nair Md

USF-LVHN SELECT

No abstract provided.

Evaluating Existing Efforts To Implement Quality Indicators In Behavioral Health Settings, Anam Ahmed

USF-LVHN SELECT

No abstract provided.

A Multi-Method Approach To Improving Preventative Care: Breast Cancer Screening At Lvhn, Gina Provenzano, Grant M. Greenberg M.D., M.H.S.A., M.A., Melanie B. Johnson Mpa, Kyle Shaak Bs

USF-LVHN SELECT

No abstract provided.

Aspirin For Prevention Of Preeclampsia: The Impact Of Recommendation Variations From 6 Professional Guidelines On Missed Opportunities For Prophlaxis, Vidhya Krishnan

USF-LVHN SELECT

No abstract provided.

Cost Savings Achieved Through Introduction Of Holep And Care Pathway, Andrew Lai Mph, Benjamin Croll, Rohan Shah Bs, Jacob Rust Bs, Angelo A. Baccala Jr Md, Mba, James Johannes Md

USF-LVHN SELECT

No abstract provided.

Fatigue Experienced By Women Before And During Myocardial Infarction: An Integrative Review, John R. Blakeman, Stephen J. Stapleton

Faculty Publications - Mennonite College of Nursing

RESEARCH QUESTION What is known about fatigue experienced by adult women during the prodromal and acute periods of myocardial infarction (MI)?

AIMS 1. Identify what is known about prodromal and acute MI fatigue experienced by women in regard to severity, distress, quality, and timing 2. Summarize the current state of the prodromal and acute MI fatigue literature and make recommendations for clinical practice and future study

J Mich Dent Assoc Mar 2018

The Journal of the Michigan Dental Association

Archival issues of the Journal of the Michigan Dental Association may include reports on the activities of the association and its members, clinical articles, information on legal and ethical practice considerations, and perspectives of interest to MDA members and those in the oral health profession.

Angioleiomyoma (Vascular Leiomyoma) Of The Oral Cavity, Swati Y. Rawal, Yeshwant B. Rawal

School of Dentistry Faculty Research and Publications

A 70-year-old male presented with a slow growing, dome shaped and painless mass of the hard palate. The mass was excised. Histopathological examination confirmed the diagnosis of a angioleiomyoma (vascular leiomyoma). A leiomyoma is an uncommon benign tumor of smooth muscle differentiation. True leiomyomas of the oral cavity are rare and most oral tumors are derived from the smooth muscle of walls of blood vessels. Therefore, they are called vascular leiomyomas or angioleiomyomas. Clinically, they may resemble a myriad other conditions both benign and malignant. A definitive diagnosis depends upon histopathological examination of the biopsied tissue in correlation with the …

Comment On U.S. Department Of Health And Human Services Rule, Public Rights/Private Conscience Project

Center for Gender & Sexuality Law

In medical facilities across the country, doctors whose conscience would require them to perform a sterilization on a patient who requests one, offer truthful information about accessing abortion services, or provide comprehensive LGBTQ+ health care are forbidden from doing so by their employer. The conscience of such medical providers is entirely ignored by the U.S. Department of Health and Human Service’s (HHS) recently proposed rule that purports to “ensure that persons or entities” providing health care “are not subjected to certain practices or policies that violate conscience, coerce, or discriminate.” As explained in a comment submitted today by the Columbia …

Surviving Difference: Endocrine-Disrupting Chemicals, Intergenerational Justice, And The Future Of Human Reproduction, Robyn Lee, Roxanne Mykitiuk

Articles & Book Chapters

Endocrine-disrupting chemicals have been identified as posing risks to reproductive health and may have intergenerational effects. However, responses to the potential harms they pose frequently rely on medicalised understandings of the body and normative gender identities. This article develops an intersectional feminist framework of intergenerational justice in response to the potential risks posed by endocrine-disrupting chemicals. We examine critiques of endocrine disruptors from feminist, critical disability and queer standpoints, and explore issues of race and class in exposures. We argue that responding to the risks posed by endocrine disruptors such as brominated flame retardants (BFRs) and phthalates requires developing a …

Efficacy And Safety Of Eslicarbazepine Acetate Monotherapy In Patients Converting From Carbamazepine., Ladislav Pazdera, Michael R. Sperling, Jay H. Harvey, Maria C. Sam, Laura A. Strom, David Blum, Todd Grinnell, Hailong Cheng

Department of Neurology Faculty Papers

OBJECTIVE: To evaluate the influence of prior use of carbamazepine (CBZ) and other antiepileptic drugs (AEDs) with a putatively similar mechanism of action (inhibition of voltage-gated sodium channels; VGSCs) on seizure outcomes and tolerability when converting to eslicarbazepine acetate (ESL), using data pooled from 2 controlled conversion-to-ESL monotherapy trials (studies: 093-045, 093-046).

METHODS: Adults with treatment-resistant focal (partial-onset) seizures were randomized 2:1 to ESL 1600 or 1200 mg once daily. The primary efficacy endpoint was study exit (meeting predefined exit criteria related to worsening seizure control) versus an historical control group. Other endpoints included change in seizure frequency, responder rate, …

Effects Of Adjunctive Eslicarbazepine Acetate On Serum Lipids In Patients With Partial-Onset Seizures: Impact Of Concomitant Statins And Enzyme-Inducing Antiepileptic Drugs., Scott Mintzer, Robert T. Wechsler, Joanne B. Rogin, Barry E. Gidal, Matthias Schwab, Elinor Ben-Menachem, Mar Carreño, Patrício Soares Da Silva, Joana Moreira, Yan Li, David Blum, Todd Grinnell

Department of Neurology Faculty Papers

PURPOSE: To evaluate the effects of eslicarbazepine acetate (ESL) on lipid metabolism and to determine whether reduced statin exposure during ESL therapy has clinical consequences.

SUBJECTS AND METHODS: We conducted a post-hoc analysis of pooled data for serum lipids (laboratory values) from three phase III, multicenter, randomized, double-blind, placebo-controlled trials of adjunctive ESL therapy (400, 800, or 1200 mg once daily) in patients with treatment-refractory partial-onset seizures. Changes from baseline in serum lipid levels were analyzed according to use of statins and/or enzyme-inducing antiepileptic drugs (EIAEDs) during the baseline period.

KEY FINDINGS: In total, 426 and 1021 placebo- and ESL-treated …