Medicine and Health Sciences Commons^™

Enhancing Elderly Advance Care Planning Experience At A Primary Care Clinic, Oi Shan Wong

Doctoral Projects

The purpose of the project was to examine if the identification of readiness for an advance care planning (ACP) discussion of elderly participants would enhance the outcomes of participants' satisfaction, improve the likelihood of having an ACP discussion and increase the completion rates of an advance directive (AD) document after an office visit.

Forty-four elderly participants, who met the selection criteria, were recruited from a primary clinic in Northern California from October 1, 2017 to December 31, 2017 (Female, n =28). All participants were randomly assigned to either an intervention group (n= 22) or a control group ( …

Prevalence And Prevention Of Diabetes In School Age Children: A Parent Education Module, Christine Mary Whitmyer

Doctoral Projects

The Center for Disease Control reports that there continues to be an increasing number of children being diagnosed with childhood-onset Type Two Diabetes Mellitus (T2DM). The recommendation is to provide education to parents regarding the risks and possible risk factors of T2DM, and strategies to prevent and treat these risk factors (Center for Disease Control [CDC], 2014). Educating parents of school age children on T2DM risk factors, and prevention practices may help to slow down this rising number of new cases. The Aim is to provide educational modules that may increase knowledge, which could in-turn change behavior, that may prevent …

Understanding Occupational Injuries, Hanbit (Joyce) Choi

Doctoral Projects

The purpose of this project is to better understand the potential negative impact of longer commute times on work-related health complaints and its relationship with frequency of work-related injuries among general assembly workers from various factories in the Bay Area. Companies in the United States seek to reduce the cost of work-related injuries by investigating the causes of and implementing necessary programs in their workplaces. According to the U.S. Census Bureau, there are about 115,000 employees who spend more than 90 minutes commuting to their jobs in the San Francisco Bay and San Jose Silicon Valley areas (2013). However, there …

Perceptions Of Chinese Women Coming To The United States To Give Birth: Birth Tourism, Juanita Childs Jaramillo

Doctoral Projects

Birth experiences and perceptions vary greatly among different cultures. There has been an increase in Chinese women who specifically come to the United States (US) to give birth to their child and return back to their native country after being cleared at the postpartum checkup. This practice is known as birth tourism. The aim of this study is to explore the perceptions of childbirth and postpartum experiences among Chinese birth tourists. Twelve women self-identifying as Chinese, between the ages of twenty-four and thirty-eight, who came to the US to give birth to their child, and who were able to read …

Home Literacy Of Dual-Language Learners In Kindergarten From Low-Ses Backgrounds, Carla Wood, Lisa Fitton, Estrella Rodriguez

Faculty Publications

This study aimed to describe home literacy (HL) activities of Spanish-/English-speaking children of low–socioeconomic status backgrounds and examine the relationship between HL and performance on standardized assessments. Parents of 65 dual-language learners (DLLs) in kindergarten completed an HL questionnaire. Parents reported an average of 17 books at home and engaged in active HL activities for 24 minutes a day on average. The relations between HL activities and performance were evaluated using correlations and regression. Analyses revealed a significant relation between HL and children’s language abilities, as measured by a bilingual measure of morphosyntax and semantics. Children’s reported interest in reading …

Short Term Development And Fate Of Mge-Like Neural Progenitor Cells In Jaundiced And Non-Jaundiced Rat Brain., Fu-Chen Yang, Julia Draper, Peter G Smith, Jay L. Vivian, Steven Shapiro, John A. Stanford

Manuscripts, Articles, Book Chapters and Other Papers

Neonatal hyperbilirubinemia targets specific brain regions and can lead to kernicterus. One of the most debilitating symptoms of kernicterus is dystonia, which results from bilirubin toxicity to the globus pallidus (GP). Stem cell transplantation into the GP to replace lost neurons and restore basal ganglia circuits function is a potential therapeutic strategy to treat dystonia in kernicterus. In this study we transplanted human medial ganglionic eminence (MGE)-like neural progenitor cells (NPCs) that we differentiated into a primarily gamma-aminobutyric acid (GABA)ergic phenotype, into the GP of non-immunosuppressed jaundiced (jj) and non-jaundiced (Nj) rats. We assessed the survival and development of graft …

Opioid-Related Critical Care Resource Use In Us Children's Hospitals., Jason M. Kane, Jeffrey D. Colvin, Allison H. Bartlett, Matt Hall

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND AND OBJECTIVES: There has been a rapid increase in the rate of pediatric opioid-related hospitalizations. It is unknown how this increase has impacted the use of pediatric critical care. Our objective in this study was to assess the trends in pediatric hospitalization for opioid ingestions in a cohort of US children's hospitals and, specifically, to evaluate the impact on pediatric critical care resource use.

METHODS: A retrospective cohort study of the Pediatric Health Information System was performed to identify hospitalizations for opioid ingestions from 2004 to 2015. Admission to the PICU and the use of naloxone, vasopressors, and ventilation …

Identifying Health Conditions, Priorities, And Relevant Multilevel Health Promotion Intervention Strategies In African American Churches: A Faith Community Health Needs Assessment., Jannette Berkley-Patton, Carole Bowe Thompson, Andrea Bradley-Ewing, Marcie Berman, Alexandria Bauer, Delwyn Catley, Kathy Goggin, Eric Williams, Cassandra Wainright, Therese Petty, Natasha Aduloju-Ajijola

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.

In Vivo Multimodal Magnetic Resonance Imaging Changes After N-Methyl-D-Aspartate-Triggered Spasms In Infant Rats, Minyoung Lee, Mi-Sun Yum, Dong-Cheol Woo, Woo-Hyun Shim, Tae-Sung Ko, Libor Velisek

NYMC Faculty Publications

Objective: Despite the serious neurodevelopmental sequelae of epileptic encephalopathy during infancy, the pathomechanisms involved remain unclear. To find potential biomarkers that can reflect the pathogenesis of epileptic encephalopathy, we explored the neurometabolic and microstructural sequelae after infantile spasms using a rat model of infantile spasms and in vivo magnetic resonance imaging techniques. Methods: Rats prenatally exposed to betamethasone were subjected to three rounds of intraperitoneal N-methyl-d-aspartate (NMDA) triggering of spasms or received saline injections (controls) on postnatal days (P) 12, 13, and 15. Chemical exchange saturation transfer imaging of glutamate (GluCEST) were performed at P15 and 22 and diffusion tensor …

Molecular Sequence Of Events And Signaling Pathways In Cerebral Metastases, Jared B. Cooper, Jennifer S. Ronecker, Michael E. Tobias, Avinash Mohan, Virany Hillard, Raj Murali, Chirag D. Gandhi, Meic H. Schmidt, Meena Jhanwar-Uniyal

NYMC Faculty Publications

Brain metastases are the leading cause of morbidity and mortality among cancer patients, and are reported to occur in about 40% of cancer patients with metastatic disease in the United States of America. Primary tumor cells appear to detach from the parent tumor site, migrate, survive and pass through the blood brain barrier in order to establish cerebral metastases. This complex process involves distinct molecular and genetic mechanisms that mediate metastasis from these primary organs to the brain. Furthermore, an interaction between the invading cells and cerebral milieu is shown to promote this process as well. Here, we review the …

Abnormal Chest X-Ray Leading To Diagnosis Of Partial Anomalous Pulmonary Venous Connection, Zahava C. Farkas, Abbas Haidry, Srikanth Yandrapalli, Marc Lim, Diwakar Jain, Wilbert S. Aronow

NYMC Faculty Publications

With the growing use of imaging to aid in both diagnosis and treatment of patients presenting with a myriad of clinical presentations, incidental findings on imaging have become commonplace. Partial anomalous pulmonary venous connection (PAPVC) is a rare congenital cardiovascular condition that often goes undiagnosed due to lack of symptoms early in life. In adulthood, it can manifest clinically as right-sided heart failure or pulmonary hypertension. We present a case of PAPVC, which, like most cases, was discovered incidentally on chest X-ray.

Perioperative Implication Of The Endothelial Glycocalyx, Jong Wook Song, Michael S. Goligorsky

NYMC Faculty Publications

The endothelial glycocalyx (EG) is a gel-like layer lining the luminal surface of healthy vascular endothelium. Recently, the EG has gained extensive interest as a crucial regulator of endothelial funtction, including vascular permeability, mechanotransduction, and the interaction between endothelial and circulating blood cells. The EG is degraded by various enzymes and reactive oxygen species upon pro-inflammatory stimulus. Ischemia-reperfusion injury, oxidative stress, hypervolemia, and systemic inflammatory response are responsible for perioperative EG degradation. Perioperative damage of the EG has also been demonstrated, especially in cardiac surgery. However, the protection of the EG and its association with perioperative morbidity needs to be …

Isoflurane Induces Neurodegenerative Changes In Pigment Epithelial Cells, Amro Ali, Thaddeus L. Wandel, Sansar C. Sharma

NYMC Faculty Publications

No abstract provided.

Himmelfarb Library Liaison Letter - April 2018, George Washington University, Himmelfarb Health Sciences Library

Himmelfarb Library Liaison Letters

No abstract provided.

At2r (Angiotensin Ii Type 2 Receptor)-Mediated Regulation Of Ncc (Na-Cl Cotransporter) And Renal K Excretion Depends On The K Channel, Kir4.1, Peng Wu, Zhong-Xiuzi Gao, Xin-Peng Duan, Xiao-Tong Su, Ming-Xiao Wang, Dao-Hong Lin, Ruimin Gu, Wen-Hui Wang

NYMC Faculty Publications

AT2R (AngII [angiotensin II] type 2 receptor) is expressed in the distal nephrons. The aim of the present study is to examine whether AT2R regulates NCC (Na-Cl cotransporter) and Kir4.1 of the distal convoluted tubule. AngII inhibited the basolateral 40 pS K channel (a Kir4.1/5.1 heterotetramer) in the distal convoluted tubule treated with losartan but not with PD123319. AT2R agonist also inhibits the K channel, indicating that AT2R was involved in tonic regulation of Kir4.1. The infusion of PD123319 stimulated the expression of tNCC (total NCC) and pNCC (phosphorylated NCC; Thr(53)) by a time-dependent way with the peak at 4 …

A Bone To Pick With A Lung Disease, Aparna Kadambi, Oleg Epelbaum, Anna Rozenshtein

NYMC Faculty Publications

No abstract provided.

Bios 6136 - Topics Of Inference In Biostatistics Ii, Lili Yu

College of Public Health: Faculty Syllabi (2014-2021)

The course will introduce large sample theory, such as law of large numbers and the central limit theorem; sampling distributions of estimators; the basis for inferences derived from hypothesis testing and confidence intervals; and simulation methods. Emphasis will be placed on how these techniques are used in biostatistical problems and applications using examples from the pharmaceutical industry.

Bios 9433 - Analysis With Missing & Miss-Specified Data, Haresh Rochani

College of Public Health: Faculty Syllabi (2014-2021)

This course is designed to provide the student with the basics of methods for analyzing data with missing data and misspecified data. This course will cover the following topics: missing data in experiments, complete case analysis, weighted complete case analysis, available case analysis, single imputation methods such as mean, regression, last value varied forward, hot deck imputation, cold deck imputation, Bayes Imputation, Multiple imputation, and non-ignorable missing data models. Prerequisite: A minimum grade of “B” in BIOS 9131. Co-requisite: BIOS 9231.

Chbe 9230 - Community-Based Public Health Program Planning And Evaluation, Andrew Hansen

College of Public Health: Faculty Syllabi (2014-2021)

This course introduces students to the theory and application of community-based program planning and evaluation. Concepts in community assessment, organization, and mobilization for the purposes of addressing identified public health concerns will serve as the foundation for the public health planning process. Appropriate techniques of partnership building, planning strategies, data collection, data analysis, and evidence-based decision-making will also be introduced.

Epid 7131 - Epidemiology Of Chronic Disease, Jian Zhang

College of Public Health: Faculty Syllabi (2014-2021)

This course is designed to introduce the student to the ever-expanding area of chronic disease epidemiology. Students will be introduced to the current status of chronic disease and control programs, methods used in chronic disease surveillance, intervention methods, and modifiable risk factors. Some of the major chronic diseases such as cancer, cardiovascular disease, chronic lung disease, diabetes and arthritis will be discussed in detail.

Epid 7233 - Public Health Surveillance Methods, Jian Zhang

College of Public Health: Faculty Syllabi (2014-2021)

This course will provide students with a strong foundation in public health surveillance of both health conditions and risk factors. The course will teach the theory and practice of surveillance supported by many examples of surveillance systems from the developed and developing world. The class will build on and reinforce basic epidemiologic concepts. Students will be given the opportunity to design and evaluate a surveillance system.

Epid 8130 - Field Methods In Epidemiology, Kelly L. Sullivan

College of Public Health: Faculty Syllabi (2014-2021)

This course addresses practical aspects of management and implementation of research studies and will focus on the conduct of research consistent with the scientific method. Topics include planning study activities, questionnaire design and implementation, and operations research.

Pubh 3138 - Multicultural Factors & Social Determinants Of Health, Joanne Chopak-Foss

College of Public Health: Faculty Syllabi (2014-2021)

Introduction to the characteristics, causes, and effects of health disparities in the United States with emphasis in health care delivery, health status and public health services. Provides students with a foundation to develop the knowledge, attitudes, and skills to become culturally competent public health professionals. Explores how health education and promotion is shaped by the cultural, social and economic contexts in which individuals function.

Pubh 3232 - Foundations Of Health Education And Promotion Practice, Joanne Chopak-Foss

College of Public Health: Faculty Syllabi (2014-2021)

This course examines current issues and topics underlying the field of health promotion and education practice including philosophical foundations of health promotion and education, ethical issues in health education and promotion, the Certified Health Education Specialist Competencies, organizations and associations in public health education and employment potential. Prerequisite(s): A minimum grade of "C" in PUBH 2131.

Pubh 3330 - Modifying Health Behaviors, Stacy W. Smallwood

College of Public Health: Faculty Syllabi (2014-2021)

This course is intended to introduce students to the learning and behavioral science theories that provide a framework for the practice of health education and promotion. Application of the theories to planning and implementing health promotion and education programs for individuals, groups, families, and communities will be emphasized. This course also introduces the students to various approaches to describing, explaining, and predicting health behaviors that have or are perceived to have significant effect on human health. Prerequisite: PUBH 2130

Envh 7237– Risk Assessment And Communication, Marina E. Eremeeva

College of Public Health: Faculty Syllabi (2014-2021)

Course introduces students to the qualitative and quantitative skills necessary to evaluate the probability of injury, disease, or death in individuals or in the general population from exposure to environmental contaminants. Hazard identification, exposure assessment, dose-response evaluation, and risk characterization processes are emphasized. Risk communication training includes developing practical skills in assessing health concerns and explaining potential health risks or risk management to the general public.

Bios 7231 – Clinical Trial Methodology, Karl E. Peace

College of Public Health: Faculty Syllabi (2014-2021)

Students are introduced to regulatory, scientific, statistical and practical aspects of methods inherent in design, monitoring and analysis of clinical trials. Clinical trials in many areas of drug development are presented, discussed and critiqued.

Epid 8230 – Observational Study Design And Analysis, Kelly L. Sullivan

College of Public Health: Faculty Syllabi (2014-2021)

This course will focus on the design and conduct of observational research designs including cohort, case-control and cross-sectional approaches. This course will provide instruction related to issues specific to observational research approaches. Students will develop and present detailed study plans for each research approach.

Hspm 7236-A - Health Informatics, Jeffery A. Jones

College of Public Health: Faculty Syllabi (2014-2021)

This course presents the knowledge, infrastructure, functions, and tools of health informatics. It explores technology, planning and management and applications in public health and health care. The emphasis is on conceptual frameworks as well as a deeper level of engagement on system applications. It focuses on the application of health technology, with a particular emphasis on the private/public sector of health management. It is designed to familiarize students with core concepts and issues confronting managers in the health sector associated with planning, implementation and evaluation of information systems. The course provides an overview of the theory, processes and applications of …

Pubh 7530 Section A The Public Health Integrative Capstone Experience, William A. Mase

College of Public Health: Faculty Syllabi (2014-2021)

This course serves as a culminating experience designed to promote refinement of the hard and soft skills necessary for the public health workforce. Throughout the semester, students acquire skills in the integration of basic public health concepts and refine the application of discipline specific knowledge. This course relies on a case-based format that promotes problem solving and critical thinking in the context of real world public health problems.