Medicine and Health Sciences Commons^™

Effectiveness Of Residency Training Programs For Increasing Confidence And Competence Among New Graduate Nurse Practitioners, Heather Parkhill, Dnp, Msn, Fnp-C

Doctor of Nursing Practice Projects

Background: Nurse practitioners (NPs) are enrolling in post-graduate residency programs that provide training and mentorship during transition to practice.

Objective: This project explored whether participation in NP residency improved feelings of confidence, competence, preparedness to provide care and job satisfaction among new graduate NPs who completed a residency program compared to new graduate NPs who did not complete a residency program.

Method: This mixed-methods study collected survey data from NPs who attended the 2017 AANP National Conference and two residency programs. A modified Misener Nurse Practitioner Job Satisfaction Scale (MNPJSS) (Misener & Cox, 2001) and Hart’s New Nurse Practitioner Preparedness …

Anatomy And Physiology I & Ii (Ung), Larry Gibson, Valerie Fambrough

Biological Sciences Grants Collections

This Grants Collection for Anatomy and Physiology I & II was created under a Round Eight ALG Textbook Transformation Grant.

Affordable Learning Georgia Grants Collections are intended to provide faculty with the frameworks to quickly implement or revise the same materials as a Textbook Transformation Grants team, along with the aims and lessons learned from project teams during the implementation process.

Documents are in .pdf format, with a separate .docx (Word) version available for download. Each collection contains the following materials:

• Linked Syllabus
• Initial Proposal
• Final Report

Exploring The Relevance Of Art Therapy In Public Education, Brandy A. Jarrell

Masters Theses

This thesis will explore art education as a therapeutic tool in a public education system. This topic will serve as a continuation of research that I conducted previously but will bring more focus upon bringing a certified art therapist into public school districts in West Virginia. Data will be collected through student surveys, interviews of professional art therapists, and administrative officials. Data will also be collected through a review of the literature surrounding the benefits of art therapy to children and adolescents. Through these sources I will explore the attitudes, beliefs, and practices of educational professionals, art therapists, administrators and …

Premedical Programs Newsletter, April-May 2018, University Of Dayton

Pre-Health Resource Center Campus Communications

Newsletter for students, staff, and faculty in the premedical and predental programs.

Assessment For Mild Cognitive Impairment: Striving For Best Practice, Julie Leigh Dalmasso

Dissertations

This dissertation is a series of three studies aimed at determining the best assessment practices for mild cognitive impairment (MCI) that can employed by speech-language pathologists (SLPs). The first study was non-experimental and descriptive examining whether three commonly used assessment instruments yielded similar categorical results. The data were analyzed to determine whether the Eight-Item Interview to Differentiate Aging and Dementia (AD8), the Mini-Mental State Examination (MMSE), and the Cognitive-Linguistic Quick Test (CLQT) identified the same participants from a neurotypical sample as having cognitive deficits. Very little agreement was found amongst the three tools.

Study two was modified to include two …

A Randomized Controlled Dosing Study Of Iyengar Yoga And Coherent Breathing For The Treatment Of Major Depressive Disorder: Impact On Suicidal Ideation And Safety Findings, Maren Nyer, Patricia Gerbarg, Marisa M. Silveri, Jennifer Johnston, Tammy M. Scott, Maya Nauphal, Liz Owen, Greylin H. Nielsen, David Mischoulon, Richard P. Brown, Maurizio Fava, Chris C. Streeter

NYMC Faculty Publications

BACKGROUND: Yoga interventions offer promise for the treatment of major depressive disorder (MDD), yet their safety and potential impact on suicidal ideation (SI) have not been well documented. This study evaluated the safety of a randomized controlled dose-finding trial of Iyengar yoga plus coherent breathing for individuals with MDD, as well as the potential effects of the intervention on SI without intent. METHODS: Participants with Beck Depression Inventory-II (BDI-II) scores >/=14 and a diagnosis of MDD (using DSM-IV criteria) were randomized to either a low dose group (LDG) or high dose group (HDG) and received a 12-week manualized intervention. The …

Association Between Pregnancy At Enrollment Into Hiv Care And Loss To Care Among Women In The Democratic Republic Of Congo, 2006-2013, Jonathan Ross, Andrew Edmonds, Donald R. Hoover, Qiuhu Shi, Kathryn Anastos, Patricia Lelo, Marcel Yotebieng

NYMC Faculty Publications

BACKGROUND: Loss to care is high among asymptomatic HIV-infected women initiated on antiretroviral therapy (ART) during pregnancy or in the postpartum period. However, whether pregnancy itself plays a role in the high loss to care rate is uncertain. We compared loss to care over seven years between pregnant and non-pregnant women at enrollment into HIV care in the Democratic Republic of Congo (DRC). METHODS: We conducted a retrospective analysis of all ART-naive women aged 15-45 initiating HIV care at two large clinics in Kinshasa, DRC, from 2007-2013. Pregnancy status was recorded at care enrollment. Patients were classified as having no …

Eat & Tell: A Randomized Trial Of Random-Loss Incentive To Increase Dietary Self-Tracking Compliance, Palakorn Achananuparp, Ee Peng Lim, Vibhanshu Abhishek, Tianjiao Yun

Research Collection School Of Computing and Information Systems

A growing body of evidence has shown that incorporating behavioral economics principles into the design of financial incentive programs helps improve their cost-effectiveness, promote individuals' short-term engagement, and increase compliance in health behavior interventions. Yet, their effects on long-term engagement have not been fully examined. In study designs where repeated administration of incentives is required to ensure the regularity of behaviors, the effectiveness of subsequent incentives may decrease as a result of the law of diminishing marginal utility. In this paper, we introduce random-loss incentive-a new financial incentive based on loss aversion and unpredictability principles-to address the problem of individuals' …

A Rare Case Of Tafro Syndrome, Elizabeth Gold Do, Ross Biggs Do

Department of Medicine

No abstract provided.

Complications Related To Esophageal Stent (Boston Scientific [Wallflex] Vs Merit Medical Endotek) Use In Benign And Malignant Esophageal Condition – A Single Center Retrospective Review., Rajesh Essrani Md, Hiral N. Shah Md, Shashin Shah Md, Jennifer E. Macfarlan Mph

Department of Medicine

No abstract provided.

Validation Of An Icd Code For Accurately Identifying Emergency Department Patients Who Suffer An Out-Of-Hospital Cardiac Arrest., Shelby K. Shelton, Steve B. Chukwulebe, David F. Gaieski, Benjamin S. Abella, Brendan G. Carr, Sarah M. Perman

Department of Emergency Medicine Faculty Papers

AIM: International classification of disease (ICD-9) code 427.5 (cardiac arrest) is utilized to identify cohorts of patients who suffer out-of-hospital cardiac arrest (OHCA), though the use of ICD codes for this purpose has never been formally validated. We sought to validate the utility of ICD-9 code 427.5 by identifying patients admitted from the emergency department (ED) after OHCA.

METHODS: Adult visits to a single ED between January 2007 and July 2012 were retrospectively examined and a keyword search of the electronic medical record (EMR) was used to identify patients. Cardiac arrest was confirmed; and ICD-9 information and location of return …

An Expert Consensus For The Management Of Chronic Hepatitis B In Asian Americans., M. J. Tong, C. Q. Pan, S.-H. B. Han, D. S.-K. Lu, S. Raman, K.-Q. Hu, J. K. Lim, H.W. Hann, A. D. Min

Division of Gastroenterology and Hepatology Faculty Papers

BACKGROUND: Hepatitis B virus (HBV) infection is common with major clinical consequences. In Asian Americans, the HBsAg carrier rate ranges from 2% to 16% which approximates the rates from their countries of origin. Similarly, HBV is the most important cause of cirrhosis, hepatocellular carcinoma (HCC) and liver related deaths in HBsAg positive Asians worldwide.

AIM: To generate recommendations for the management of Asian Americans infected with HBV.

METHODS: These guidelines are based on relevant data derived from medical reports on HBV from Asian countries as well as from studies in the HBsAg positive Asian Americans. The guidelines herein differ from …

Evaluating The Impact Of A Standardized Education Class On A Person Diagnosed With Chronic Kidney Disease, Stage Iv, Nancy K. Uhland, Dnp, Msn, Rn, Fnp-C

Doctor of Nursing Practice Projects

Background: Chronic kidney disease (CKD) is a complex, progressive, and costly disease impacting more than 26 million Americans. Providing effective education is necessary so the patient may actively participate in managing the disease process, but the effectiveness of the delivery of education to the patient with CKD is not well-known.

Objective: To evaluate the effectiveness of a standardized education class on the basic kidney knowledge of persons diagnosed with CKD, stage IV.

Method: This pilot study, using a one-group pre and post-test design, was conducted in an outpatient nephrology clinic located in Washington, D.C. The study participants, recruited using census …

Effects Of An Online Diabetes Self-Management Educational Class On Perceived Self-Efficacy In Patients With Type 2 Diabetes Mellitus, Samantha L. Sugarman, Dnp, Ba, Bsn, Msn, Fnp-C

Doctor of Nursing Practice Projects

Background: Diabetes is a complex, chronic disease that, without adequate glycemic control, may result in avoidable complications. Without proper diabetes self-management education, achieving good glycemic control is difficult. Furthermore, lacking self-efficacy to perform such tasks may prevent even the most educated patients from achieving good glycemic control. Studies have shown that live diabetes education has improved self-efficacy in patients with diabetes, but few look at the effects of a lecture-style educational format in an online approach.

Objectives: The purpose of this study is to determine if an online, lecture-style diabetes self-management educational class will improve self-efficacy among patients with type …

Modafinil For The Improvement Of Patient Outcomes Following Traumatic Brain Injury, Amne Borghol, Michael Aucoin, Ifeanyi Onor, Dana Jamero, Fadi Hawawini

Faculty and Staff Publications

Objective.  The authors sought to assess the literature evidence on the efficacy of modafinil use in patients with fatigue or excessive daytime sleepiness (EDS) secondary to traumatic brain injury (TBI).Method of Research. A literature search of Medline and PubMed was performed using the EBSCOhost database. Primary literature, observational studies, meta-analyses, case reports, and systematic reviews were assessed for content regarding modafinil and psychostimulant use in patients with TBI. Of the 23 articles collected, three randomized, controlled studies, three observational studies, one case report, and two systematic reviews gave a description of modafinil use in TBI patients.Results and Conclusion. Modafinil is …

Multi-Scale Fluid Flow Analysis Of The Cardiovascular System, Zaid Mahmood

Doctoral Dissertations and Master's Theses

The hypoplastic left heart syndrome (HLHS) is one of the rarest congenital heart diseases affecting infants. Out of 150 babies born, one baby suffers from congenital heart disease. Furthermore, nine percent out of those suffering from congenital heart disease specifically suffer from hypoplastic left heart syndrome (HLHS). To this end, the Fontan operation which is a procedure to generate a harmonic blood flow in single functioning ventricle patients has been executed to palliate HLHS patients. In this operation, the inferior vena cava (IVC) and the superior vena cava (SVC), carrying the low-oxygenated blood returning from the lower and upper body …

Effects Of Atypical Antipsychotic Drugs On Qt Interval In Patients With Mental Disorders, Wilbert S. Aronow, Tatyana Shamliyan

NYMC Faculty Publications

Background: Drug-induced QT prolongation is associated with higher risk of cardiac arrhythmias and cardiovascular mortality. We investigated the effects of atypical antipsychotic drugs on QT interval in children and adults with mental disorders. Methods: We conducted random-effects direct frequentist meta-analyses of aggregate data from randomized controlled trials (RCT) and appraised the quality of evidence using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology. Our search in PubMed, EMBASE, the Cochrane Library, clinicaltrials.gov, and PharmaPendium up to October 2017 identified studies that examined aripiprazole, quetiapine, risperidone, olanzapine, ziprasidone and brexpiprazole. Results: Low quality evidence suggests that aripiprazole (four meta-analyses …

Integration Of A Sensory Driven Model For Hand Grasp Function In 3d Printed Prostheses, Austin T. Hetherington

Senior Theses

My Honors Thesis was completed through the Biomedical Engineering senior design project I worked on. Our project took a mechanically operated 3D printed prosthetic hand and automated the process by which it makes a grasp. The purpose of this project was to provide an affordable, automatic prosthetic hand to those either capable and incapable of wrist flexion. The current 3D printed prosthetic models require users to bend their wrist to initiate a simple grasp. However, our design took an alternative approach by using an EMG sensor placed on the ventral side of the forearm to record muscle activity, which, upon …

Acth And Pmx53 Recover Synaptic Transcriptome Alterations In A Rat Model Of Infantile Spasms, Dumitru Iacobas, Tamar Chachua, Sanda Iacobas, Melissa Benson, Karin Borges, Jana Veliskova, Libor Velisek

NYMC Faculty Publications

We profiled the gene expression in the hypothalamic arcuate nuclei (ARC) of 20 male and 20 female rats to determine the infantile spasms (IS) related transcriptomic alteration of neurotransmission and recovery following two treatments. Rats were prenatally exposed to betamethasone or saline followed by repeated postnatal subjection to NMDA-triggered IS. Rats with spasms were treated with ACTH, PMX53 or saline. Since ACTH, the first line treatment for IS, has inconsistent efficacy and potential harsh side effects, PMX53, a potent complement C5ar1 antagonist, was suggested as a therapeutic alternative given its effects in other epilepsy models. Novel measures that consider all …

Early Relapse After Autologous Hematopoietic Cell Transplantation Remains A Poor Prognostic Factor In Multiple Myeloma But Outcomes Have Improved Over Time, Shaji K. Kumar, Angela Dispenzieri, Raphael Fraser, Fei Mingwei, Gorgun Akpek, Robert Cornell, Mohamed Kharfan-Dabaja, Cesar Freytes, Shahrukh Hashmi, Gerhard C. Hildebrandt, Leona Holmberg, Robert Kyle, Hillard Lazarus, Cindy Lee, Jospeh Mikhael, Taiga Nishihori, Jason Tay, Saad Usmani, David Vesole, Ravi Vij, Baldeep Wirk, Amrita Krishnan, Cristina Gasparetto, Tomer Mark, Yago Nieto, Parameswaran Hari, Anita D'Souza

Internal Medicine Faculty Publications

Duration of initial disease response remains a strong prognostic factor in multiple myeloma (MM) particularly for upfront autologous hematopoietic cell transplant (AHCT) recipients. We hypothesized that new drug classes and combinations employed prior to AHCT as well as after post-AHCT relapse may have changed the natural history of MM in this population. We analyzed the Center for International Blood and Marrow Transplant Research database to track overall survival (OS) of MM patients receiving single AHCT within 12 months after diagnosis (N=3256) and relapsing early post-AHCT (< 24 months), and to identify factors predicting for early vs late relapses (24−48 months post-AHCT). Over three periods (2001–2004, 2005–2008, 2009–2013), patient characteristics were balanced except for lower proportion of Stage III, higher likelihood of one induction therapy with novel triplets and higher rates of planned post-AHCT maintenance over time. The proportion of patients relapsing early was stable over time at 35–38%. Factors reducing risk of early relapse included lower stage, chemosensitivity, transplant after 2008 and post-AHCT maintenance. Shorter post-relapse OS was associated with early relapse, IgA MM, Karnofsky < 90, stage III, > 1 line of induction and lack of maintenance. Post-AHCT early relapse remains …

Chemiluminescent Agents For In Vivo Imaging, Jian Cao

Chemistry Theses and Dissertations

Chemiluminescence is the light production directly from a highly exothermic chemical reaction by generating electronically excited species, and the light will be generated upon relaxation to the ground state. We utilize this light as the readout to construct imaging agents for reactive species. Chemiluminescence as an imaging modality has many advantages compared with current widely used imaging modalities, such as fluorescence and bioluminescence. The main advantages are the elimination of extraneous light excitation or genetic modification, which are required for fluorescence and bioluminescence imaging. Therefore, chemiluminescence as a imaging modality holds great potential for in vivo imaging.

In this dissertation, …

The Dynamics Of Concussion: Mapping Pathophysiology, Persistence, And Recovery With Causal-Loop Diagramming, Erin S. Kenzie, Elle L. Parks, Erin D. Bigler, David W, Wright, Miranda M. Lim, James C. Chesnutt, Gregory W.J. Hawryluk, Wayne Gordon, Wayne Wakeland

Complex Systems Faculty Publications and Presentations

Concussion, also known as mild traumatic brain injury (mTBI),1 is a significant public health issue responsible for a variety of cognitive, emotional, and somatic symptoms and deficits (3). It is unclear why some individuals appear to recover relatively quickly while others suffer prolonged symptoms and impairments (4–7). Robust clinical means of diagnosis, prognosis, and treatment are also lacking (8–11). Research is hindered by an inadequate classification system for traumatic brain injury (TBI) (12), “poor” study quality (13, 14), disagreement about appropriate inclusion and exclusion criteria for concussion (8, 15), and an incomplete understanding of underlying pathophysiology (16–18). The heterogeneity and …

Iowa Conference On Communicative Disorders [Program, 2018], Iowa Conference On Communicative Disorders

Iowa Conference on Communicative Disorders Programs

The Iowa Conference on Communicative Disorders provides continuing education activities in speech- language pathology that are acceptable to the State of Iowa and the American Speech-Language and Hearing Association. Areas of emphasis include adults and pediatrics.

Development Of An Evidence-Based Strength Training Program For Individuals With Dementia Participating In Adult Day Services, Jaclyn Franz

Honors Theses

Falling and loss of mobility present serious risks for elderly adults, especially those with cognitive impairments such as dementia. These risks are shown to be significantly reduced when elderly adults participate in exercises focusing on strength and balance of sufficient intensity. Despite these potential benefits, many adult day programs do not incorporate exercise in a systematic and progressive fashion to achieve desirable improvements in function.

The purpose of this project was to develop an evidence-based exercise program, later titled Simply Strong, for reducing fall risk and improving mobility in elderly adults with dementia participating in Goodwill Easter Seals adult day …

Health Policy Responses And Infrastructure Re-Use In Host Cities Of Mega-Sporting Events In Non-Traditional Host Countries, Andrew Kramer

Honors Theses

The IOC has increased their focus on long-term effects for hosts of the Olympic Games, coinciding with increased academic interest in studying the positive and negative legacies of mega-sporting events in the host city. Recently, cities in relatively underdeveloped countries have won bids for mega-sporting events. City officials and the IOC have begun marketing mega-sporting events as transformational events for underdeveloped cities’ economies, urban infrastructure, social landscape, and health. The thesis investigates the impact of hosting mega-sporting events for public health and infrastructure in three case studies: the 2016 Summer Olympics in Rio de Janeiro, Brazil, the 2014 Winter Olympics …

Interference Of The Inflammasome Via Interferonβ, Madeline Sauer

Honors Theses

Metabolic disorders such as type two diabetes mellitus (T2DM) and obesity are known to have a chronic low grade inflammatory tissue environment as well as an increase in excess lipids. Current research suggests that a tightly regulated oligoprotein complex known as the NLRP3 inflammasome is highly activated in T2DM and obesity. However, it is not well understood the interplay between excess lipids, which was previously shown in our lab to cause lysosome damage, and inflammation. A key transcription factor that is known to have both an inflammatory effect as well as an effect on lipid metabolism is PPARγ. For this …

The Effect Of Oral Rehydration Solutions (Sports Drinks) On Strength, Speed, And Endurance: A Field Study, Andrea Wisniewski

Honors Theses

Research Objective: The specific objective of this study is to contrast three different oral rehydration solutions (sports drinks) during a prolonged exercise trial on muscular strength, speed, and endurance in healthy young adult males.

Methodology: Thirteen (13) healthy male subjects will participate in a 5-mile walk on an outdoor track carrying a 40-pound rucksack on three separate occasions while drinking one of three (3) oral rehydration solutions (sports drinks) at a rate of 250 mL every 15 minutes as recommended by the American College of Sports Medicine. All three trails will be performed outdoors and differences in environmental conditions accounted …

Microbial Co-Infection Alters Macrophage Polarization, Phagosomal Escape, And Microbial Killing, Nikita H. Trivedi, Jieh-Juen Yu, Chiung-Yu Hung, Richard P. Doelger, Christopher S. Navara, Lisa Y. Armitige, Janakiram Seshu, Anthony P. Sinai, James P. Chambers, M. Neal Guentzel, Bernard P. Arulanandam

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Macrophages are important innate immune cells that respond to microbial insults. In response to multi-bacterial infection, the macrophage activation state may change upon exposure to nascent mediators, which results in different bacterial killing mechanism(s). In this study, we utilized two respiratory bacterial pathogens, Mycobacterium bovis (Bacillus Calmette Guẻrin, BCG) and Francisella tularensis live vaccine strain (LVS) with different phagocyte evasion mechanisms, as model microbes to assess the influence of initial bacterial infection on the macrophage response to secondary infection. Non-activated (M0) macrophages or activated M2-polarized cells (J774 cells transfected with the mouse IL-4 gene) were first infected with BCG for …

Culturally Sensitive Diabetic Group Education, Kelly Marie Flores

Doctoral Projects

This study assessed the effectiveness of a culturally sensitive type 2 diabetes group education program delivered to Hispanic women in Merced County. Design: A pre-test post-test design. Purposeful sampling was used. Fifteen Hispanic women from a Merced County outpatient clinic were invited to participate in a culturally relevant group education workshop over a 6-week period. Four (N=4) women accepted the invitation, completed the educational workshop, and participated in the assessments. Topics discussed in the education sessions included: (1) diabetic diet, (2) exercise, (3) blood sugar monitoring, (4) medication, and (5) preventative health. A knowledge check was completed by …

Nurse Practitioner Clinical Education: Evaluation Of A Clinical Residency Model, Lisa Wilson Hood

Doctoral Projects

A new clinical residency education model was developed and implemented in response to a family nurse practitioner program’s difficulty in securing and maintaining qualified preceptors and clinical sites for students in the program, and a community hospital’s shortage of nurse practitioners for their rural healthcare clinics. This Doctor of Nursing Practice project conducted an evaluation on this new model. The evaluation results showed that the clinical residency model met standards of nurse practitioner education, incorporated nursing leader recommendations for new clinical models, and proved to be an effective model for clinical education.