Medicine and Health Sciences Commons^™

Usm’S Clinical Rehabilitation Counseling (Clrc) Social Media Outreach, Heather Roberts

Thinking Matters Symposium Archive

For the service-learning practicum capstone, I assisted Dr. Charles Bernaccio and Tiffany Reagan on the media outreach (LinkedIn page) for the Clinical Rehabilitation Counseling (CLRC) master’s program here at the University of Southern Maine.

The mission of the USM Rehabilitation Counseling (RC) specialty program is to promote quality rehabilitation services to persons with disabilities by:

(1) preparing qualified rehabilitation professionals;

(2) providing services to rehabilitation professionals and organizations; and

(3) sponsoring rehabilitation-related research and training.

Quantitative 3-D Head Ultrasound Measurements Of Ventricle Volume To Determine Thresholds For Preterm Neonates Requiring Interventional Therapies Following Posthemorrhagic Ventricle Dilatation, Jessica Kishimoto, Aaron Fenster, David S.C. Lee, Sandrine De Ribaupierre

Anatomy and Cell Biology Publications

Dilatation of the cerebral ventricles is a common condition in preterm neonates with intraventricular hemorrhage. This posthemorrhagic ventricle dilatation (PHVD) can lead to lifelong neurological impairment through ischemic injury due to increased intracranial pressure, and without treatment can lead to death. Two-dimensional ultrasound (US) through the fontanelles of the patients is serially acquired to monitor the progression of PHVD. These images are used in conjunction with clinical experience and physical exams to determine when interventional therapies such as needle aspiration of the built up cerebrospinal fluid (ventricle tap, VT) might be indicated for a patient; however, quantitative measurements of the …

Treating Pediatric Neuromuscular Disorders: The Future Is Now, James J Dowling, Hernan D Gonorazky, Ronald D Cohn, Craig Campbell

Paediatrics Publications

Pediatric neuromuscular diseases encompass all disorders with onset in childhood and where the primary area of pathology is in the peripheral nervous system. These conditions are largely genetic in etiology, and only those with a genetic underpinning will be presented in this review. This includes disorders of the anterior horn cell (e.g., spinal muscular atrophy), peripheral nerve (e.g., Charcot-Marie-Tooth disease), the neuromuscular junction (e.g., congenital myasthenic syndrome), and the muscle (myopathies and muscular dystrophies). Historically, pediatric neuromuscular disorders have uniformly been considered to be without treatment possibilities and to have dire prognoses. This perception has gradually changed, starting in part …

The Turkish Version Of The Juvenile Arthritis Multidimensional Assessment Report (Jamar), Erkan Demirkaya, Seza Ozen, Betul Sozeri, Nuray Aktay Ayaz, Ozgur Kasapcopur, Erbil Unsal, Balahan Bora Makay, Kenan Barut, Berna Eren Fidanci, Dogan Simsek, Mustafa Cakan, Alessandro Consolaro, Francesca Bovis, Nicolino Ruperto

Paediatrics Publications

The Juvenile Arthritis Multidimensional Assessment Report (JAMAR) is a new parent/patient reported outcome measure that enables a thorough assessment of the disease status in children with juvenile idiopathic arthritis (JIA). We report the results of the cross-cultural adaptation and validation of the parent and patient versions of the JAMAR in the Turkish language. The reading comprehension of the questionnaire was tested in 10 JIA parents and patients. Each participating centre was asked to collect demographic, clinical data and the JAMAR in 100 consecutive JIA patients or all consecutive patients seen in a 6-month period and to administer the JAMAR to …

Osteoarthritis, Cerebrovascular Dysfunction And The Common Denominator Of Inflammation: A Narrative Review, B. K. Al-Khazraji, C. T. Appleton, F. Beier, T. B. Birmingham, J. K. Shoemaker

Physiology and Pharmacology Publications

© 2018 The Author(s) Objective: Population-based cohort studies suggest an association between osteoarthritis (OA) and cerebrovascular disease, yet the mechanisms underlying vascular comorbidities in OA remain unclear. The purpose of this narrative review is to discuss the literature examining inflammation in OA with a focus on physiological mechanisms, and whether overlapping mechanisms exist in cerebrovascular dysfunction. Method: A literature search was conducted in PubMed using combinations of search terms: osteoarthritis, cerebrovascular (disease/dysfunction/risk), cardiovascular (disease/dysfunction/risk), aging/ageing, inflammation, inflammatory mediators, cytokine, c-reactive protein, interleukin, advanced glycation end-products, metabolic syndrome, reactive oxidative species, cognitive impairment, (vascular-related) dementia, small cerebral vessel disease, endothelial function, …

Development Of A Pulmonary Imaging Biomarker Pipeline For Phenotyping Of Chronic Lung Disease, Fumin Guo, Dante Capaldi, Miranda Kirby, Khadija Sheikh, Sarah Svenningsen, David G Mccormack, Aaron Fenster, Grace Parraga

Medical Biophysics Publications

We designed and generated pulmonary imaging biomarker pipelines to facilitate high-throughput research and point-of-care use in patients with chronic lung disease. Image processing modules and algorithm pipelines were embedded within a graphical user interface (based on the .NET framework) for pulmonary magnetic resonance imaging (MRI) and x-ray computed-tomography (CT) datasets. The software pipelines were generated using C++ and included: (1) inhaled

Appraisal Of Clinical Practice Guideline: Management Of Neck Pain, Pavlos Bobos, Joy C. Macdermid

Bone and Joint Institute

No abstract provided.

Clinimetrics: Upper Extremity Functional Index, Vanitha Arumugam, Joy C. Macdermid

Bone and Joint Institute

No abstract provided.

Beneficial Pleiotropic Antidepressive Effects Of Cardiovascular Disease Risk Factor Interventions In The Metabolic Syndrome, Stephanie J. Frisbee, Sarah S. Singh, Dwayne N. Jackson, Kent A. Lemaster, Samantha A. Milde, J. Kevin Shoemaker, Jefferson C. Frisbee

Bone and Joint Institute

© 2018 The Authors. Background--Although the increased prevalence and severity of clinical depression and elevated cardiovascular disease risk represent 2 vexing public health issues, the growing awareness of their combined presentation compounds the challenge. The obese Zucker rat, a model of the metabolic syndrome, spontaneously develops significant depressive symptoms in parallel with the progression of the metabolic syndrome and, thus, represents a compelling model for study. The primary objective was to assess the impact on both cardiovascular outcomes, specifically vascular structure and function, and depressive symptoms in obese Zucker rats after aggressive treatment for cardiovascular disease risk factors with long-term …

Seeing The Forest And The Trees: Default Local Processing In Individuals With High Autistic Traits Does Not Come At The Expense Of Global Attention., Ryan A Stevenson, Sol Z Sun, Naomi Hazlett, Jonathan S Cant, Morgan D Barense, Susanne Ferber

Brain and Mind Institute Researchers' Publications

Atypical sensory perception is one of the most ubiquitous symptoms of autism, including a tendency towards a local-processing bias. We investigated whether local-processing biases were associated with global-processing impairments on a global/local attentional-scope paradigm in conjunction with a composite-face task. Behavioural results were related to individuals' levels of autistic traits, specifically the Attention to Detail subscale of the Autism Quotient, and the Sensory Profile Questionnaire. Individuals showing high rates of Attention to Detail were more susceptible to global attentional-scope manipulations, suggesting that local-processing biases associated with Attention to Detail do not come at the cost of a global-processing deficit, but …

Tdp-43 Gains Function Due To Perturbed Autoregulation In A Tardbp Knock-In Mouse Model Of Als-Ftd, Matthew A. White, Eosu Kim, Amanda Duffy, Robert Adalbert, Benjamin U. Phillips, Owen M. Peters, Jodie Stephenson, Sujeong Yang, Francesca Massenzio, Ziqiang Lin, Simon Andrews, Anne Segonds-Pichon, Jake Metterville, Lisa M. Saksida, Richard Mead, Richard R. Ribchester, Youssef Barhomi, Thomas Serre, Michael P. Coleman, Justin Fallon, Timothy J. Bussey, Robert H. Brown, Jemeen Sreedharan

Brain and Mind Institute Researchers' Publications

© 2018 The Author(s). Amyotrophic lateral sclerosis-frontotemporal dementia (ALS-FTD) constitutes a devastating disease spectrum characterized by 43-kDa TAR DNA-binding protein (TDP-43) pathology. Understanding how TDP-43 contributes to neurodegeneration will help direct therapeutic efforts. Here we have created a TDP-43 knock-in mouse with a human-equivalent mutation in the endogenous mouse Tardbp gene. TDP-43Q331K mice demonstrate cognitive dysfunction and a paucity of parvalbumin interneurons. Critically, TDP-43 autoregulation is perturbed, leading to a gain of TDP-43 function and altered splicing of Mapt, another pivotal dementia-associated gene. Furthermore, a new approach to stratify transcriptomic data by phenotype in differentially affected mutant mice revealed 471 …

Advances In Understanding The Development Of The Mathematical Brain, Daniel C. Hyde, Daniel Ansari

Brain and Mind Institute Researchers' Publications

No abstract provided.

Maternal Nicotine Exposure Leads To Augmented Expression Of The Antioxidant Adipose Tissue Triglyceride Lipase Long-Term In The White Adipose Of Female Rat Offspring., Nicole Barra, Taylor Vanduzer, Alison C. Holloway, Daniel B. Hardy

Physiology and Pharmacology Publications

Globally, approximately 10-25% of women smoke during pregnancy. Since nicotine is highly addictive, women may use nicotine containing products like nicotine replacement therapies for smoking cessation, but the long-term consequences of early life exposure to nicotine remain poorly defined. Our laboratory has previously demonstrated that maternal nicotine exposed (MNE) rat offspring exhibit hypertriglyceridemia due to increased hepatic de novo lipogenesis. Hypertriglyceridemia may also be attributed to impaired white adipose tissue (WAT) lipid storage; however, the effects of MNE on WAT are not completely understood. We hypothesize that nicotine-induced alterations in adipose function (e.g. lipid storage) underlie dyslipidemia in MNE adults. …

Descriptive Report Of The Impact Of Fatigue And Current Management Strategies In Cerebral Palsy., Laura K Brunton

Physical Therapy Publications

Purpose: Describe the impact of fatigue and self-management practices for adolescents and young adults with cerebral palsy (CP).

Methods: Survey of 124 people with CP with the Fatigue Impact and Severity Self-Assessment (FISSA).

Results: People in GMFCS Level I experienced little impact of fatigue with high proportions of this group disagreeing to statements about fatigue impacting their general activities, mobility and social activities. People in GMFCS Levels II-V reported impact of fatigue on activities. Differences between groups were evident in questions related to fatigue interference with length of time for physical activity and with motivations to participate in social …

Melodies, Memories, And Meaning: The Use Of Music Therapy For Persons With Dementia, Emily A. Carl

Selected Honors Theses

Dementia is a growing public health issue, as there are 24.3 million people currently diagnosed worldwide. Being that there is no cure, non-pharmacological interventions are important to optimize quality of life for this population. Music therapy is a nonpharmacological intervention with fine usability for dementia patients. This thesis will examine the positive effects of music therapy on the behavioral symptoms, mood management, self-esteem, language skills, cognition, and reminiscence for the individual with dementia based on existing literature and will provide practice recommendations for the clinical use of music therapy and research. A short literature review will focus on the field …

Increasing Cervical Cancer Screening In Hiv Positive Women By Introduction Of A Provider Prompted Algorithm Tool: A Quality Improvement Project, Aubri B. Hickman

Doctoral Projects

Continuous quality improvement projects and appropriate documentation are an essential component to continue to receive Ryan White grant funding. Compliance with mandated aspects of quality improvement is an extremely important concept-specifically for a clinic setting that cares for the largest HIV positive population in the state of Mississippi. The Health Resources and Services Administration (HRSA) provides directives mandating that quality improvement projects should be applicable to areas of need and provide for outcomes that ensure quality care for HIV positive individuals (2016).

Initially, this clinic’s rate of compliance with the HRSA Cervical Cancer Screening Performance Measure was subpar to the …

Alumni Journal - Volume 89, Number 1, Loma Linda University School Of Medicine

Alumni Journal, School of Medicine

Features
12 | An Experience Rich in History, Beauty, and Fellowship
14 | Department Reports: Anesthesiology and Internal Medicine
22 | In Search of the Celestial
32 | APC 2018: A Preview

Departments
2 | From the Editor
5 | From the President
8 | From the Dean
9 | The Student Fund
10 | School of Medicine News
39 | Letter to AIMS Members
40 | Book Review
43 | Classified/Placement Ads
44 | Alumni News
46 | In Memoriam
50 | Historical Snapshot
51 | What's Up Doc?

Extras
4 | Board of Directors and Holding Fund Ballot …

Trx® Suspension Training In Improving Single Leg Strength And Confidence In A Female Soccer Player Post Acl Reconstruction, Allison Evron, David Kempfert

St. Augustine, Spring 2018

The purpose of this case report is to describe the combination of TRX® suspension training with a functional lower extremity rehabilitation program in an ACLR patient whose lacking dynamic knee control and lower extremity strength and endurance.

Scapular Mobilization Combined With Thoracic Manipulation For Treating Subacromial Impingement Syndrome In An Elderly Female: A Case Report, Tyler Alford, David Kempfert

St. Augustine, Spring 2018

Purpose: To describe the treatment of a patient with Subacromial Impingement Syndrome (SAIS) pathology utilizing a combination of manual therapy techniques at the scapulothoracic joint and the upper thoracic spine along with more traditional scapular stabilization exercises.

Myofascial Manipulation To Alleviate Forearm And Hand Weakness And Numbness In A Female Competitive Rock Climber, Ben Kern, Evan M. Pucillo

St. Augustine, Spring 2018

The purpose of this case report is to describe the effectiveness of myofascial manipulation along with therapeutic exercise on a patient with weakness, numbness, and tingling in the distal upper extremities in order to return to competitive rock climbing.

Can You Dig? Returning To Volleyball After Arthroscopic Medial Plica Excision, Kelsy Wheeler, Lisa Chase

St. Augustine, Spring 2018

The purpose of this case report is to describe the rehabilitation and return-to-sport process following arthroscopic medial plica excision for a patient who had previously undergone unsuccessful conservative management for anterior knee pain.

Ease Into It. Effects Of Mobilization With Movement Utilizing Patients Body Weight, Casey Brown, Matthew L. Daugherty

St. Augustine, Spring 2018

The purpose of this case report is to utilize mobilization with movement (MWM) to restore knee flexion in a patient with delayed quadriceps tendon repair.

The Effectiveness Of Physical Therapy Interventions For A Six-Year-Old Boy With Monosomy 18p, Grace Lewis, Catherine M. Andrea

St. Augustine, Spring 2018

The purpose of this case report is to explain the utilization and effectiveness of physical therapy interventions for improving gross motor abilities in a six-year-old boy diagnosed with Monosomy 18p.

When All Else Fails: Management Of An Irreparable Rotator Cuff With Capsular Reconstruction And Physical Therapy Targeting Accommodative Musculature, Savannah Faulk, Douglas Steele

St. Augustine, Spring 2018

The purpose of this case report is to describe the rehabilitative outcomes on a superior capsular reconstruction surgery following the re-injury of a surgically repaired rotator cuff (RTC) and glenoid labrum that was deemed irreparable.

Walkin’ On Air: Alter-G Gait Training In A Male With Hereditary Spastic Paraplegia, Kimberly Richardson, Evan M. Pucillo

St. Augustine, Spring 2018

The purpose of this case report is to determine the effectiveness of LBPPS treadmill training, using the Alter-G, to improve the spatiotemporal parameters of gait for a patient with HSP.

Reforming Range Of Motion: The Use Of The Pilates Reformer In A Female With Postoperative Adhesive Capsulitis, Lanzi A. Young, Larry J. Mengelkoch

St. Augustine, Spring 2018

The purpose of this case report is to describe the rehabilitation outcomes of a 62-year-old female with post operative adhesive capsulitis using Pilates-based intervention in conjunction with standard Physical Therapy.

To Transplant Or Not To Transplant? The Successful Treatment Of A Lateral Meniscus Transplant, Jaime Rubin, Matthew L. Daugherty

St. Augustine, Spring 2018

The purpose of this case report was to demonstrate how physical therapists can successfully manage a young patient who received the rare lateral meniscal transplant procedure.

An Orthopedic Solution To A Neurological Problem -Core Stabilization Post Stroke: A Case Report, James E. Smith, Lindsay Perry

St. Augustine, Spring 2018

The purpose of this case report is to report the outcomes of combining manual therapy techniques for spinal mobility and stability with traditional neurological approaches to stroke rehabilitation.

Non-Organic Motor Disorder: Combatting The Effects Of Stress On Functional Mobility, Kelsi Taylor, Lindsay Perry

St. Augustine, Spring 2018

The purpose of the case report was to show how neurological symptoms can be effectively treated with task-specific interventions and the role of stress in symptom presentation in patients with somatoform disorders.

Relieve Pain And Continue To Train! Dry Needling Intervention For Foot Tendinopathies, Aubrey Kuester, Lisa Chase

St. Augustine, Spring 2018

The purpose of this case report is to describe a multimodal physical therapy intervention of dry-needling, manual therapy and low-dye anti-pronation taping for a female marathon runner with bilateral plantar fasciitis, Achilles and peroneal tendinopathies.