Medicine and Health Sciences Commons^™

Family-Centered Caregiving From Hospital To Home: Coping With Trauma And Building Capacity With The Hope For Families Model, Anna Newcomb, L Gordon Moore, Holly C. Matto

Patient Experience Journal

Informal caregivers and families play a significant role in the recovery process of trauma survivors. However, the needs and outcomes of orthopedic caregiving family members in the months following traumatic injury have received almost no attention in the literature. Our study sought to understand the factors impacting orthopedic trauma families’ experience and their ability to cope and provide care post-acute hospitalization. Based on these findings, we designed a hospital-based program to enhance family coping and adjustment post-discharge. Caregivers (N=12) of patients with orthopedic trauma injury engaged in three in-depth semi-structured face-to-face interviews to identify their most salient concerns. Once home, …

How Patients View Their Contribution As Partners In The Enhancement Of Patient Safety In Clinical Care, Marie-Pascale Pomey, Nathalie Clavel, Ursulla Aho-Glele, Noemie Ferré, Paloma Fernandez-Mcauley

Patient Experience Journal

Despite the call from the World Health Organization for more active involvement from patients in the prevention of health care-related risks, there is still insufficient evidence about how patients can be more proactive in the safety of their own care. This study helps understand the perspective of patients as partners regarding their roles, as well as their relatively untapped potential in detecting and limiting adverse events (AEs) for patient safety. 17 patients-as-partners were interviewed on five themes: 1) Behavior of patients/relatives for avoiding AEs; 2) Competencies sought in patients/relatives to play an active role in patient safety; 3) Factors limiting …

The Patient Experience With Shared Decision-Making In Lung Cancer: A Survey Of Patients, Significant Others Or Care Givers, Laurie E. Gaspar, Howard J. West, Bonnie J. Addario, D Ross Camidge

Patient Experience Journal

A survey (via SurveyMonkey) was sent to lung cancer patients, their caregivers or significant others asking about their experience in making difficult treatment decisions. Of the 198 respondents, 118 (69%) indicated that they had faced a difficult decision with respect to their lung cancer treatment. Of those, 73% indicated that they would have desired that the decision be made with their physician using a shared decision-making process, and 58% perceived that such a process had occurred. In addition, only 23% of respondents indicated that they had had the right amount of information when making the decision. Fortunately, only 9% of …

Barriers And Facilitators To Family Participation In The Care Of Their Hospitalized Loved Ones, Lynda Bélanger, Marie Desmartis, Martin Coulombe

Patient Experience Journal

This study’s objective was to better understand family members’ experiences in order to identify how healthcare organizations can facilitate their participation in the care of a hospitalized loved one. Eighteen individuals at the bedside of a hospitalized loved one were interviewed individually. Roles at the bedside and factors that facilitated their participation or represented barriers were examined. A qualitative analysis using a mixed inductive/deductive approach was performed. Reassurance and emotional support, as well as sharing information with the healthcare team emerged as main roles. Quality and timeliness of the information received about the patient’s condition, prognosis and changes in medical …

A Framework For Conceptualizing How Narratives From Health-Care Consumers Might Improve Or Impede The Use Of Information About Provider Quality, Melissa L. Finucane, Steven C. Martino, Andrew M. Parker, Mark Schlesinger, Rachel Grob, Jennifer L. Cerully, Lise Rybowski, Dale Shaller

Patient Experience Journal

Consumers choosing a health-care provider have access to diverse information including narratives by patients about their prior experiences. However, little research has examined how narratives might improve or impede the use of information about the quality of providers’ performance. This paper describes a conceptual framework for examining mechanisms by which narrative information might influence consumer judgments and decisions about providers. We conducted a conceptual review of risk communication and behavioral decision research. We synthesized the literature to form the foundation of a conceptual framework for assessing how narrative information about provider quality impacts consumer decisions about providers. We identified four …

Patients’ Stories Of Encounters With Doctors: Expectations And Anxieties, Daniella Arieli, Batya Tamir

Patient Experience Journal

The study contributes to the understanding of how patients experience encounters with doctors. The study is based on the gathering and analysis of subjective stories of 'healthy' patients who live in Israel about their encounters with doctors. On the one hand, medical encounters were described as functional ritualistic events, and the doctor was described as an indifferent clerk. On the other hand, and often at the same time, medical encounters were perceived as incredibly meaningful and potentially fateful events, and the doctor as a supreme authority. Four main inter-connected expressions of this were: 1. The encounter as a ritual: A …

The Gift Of Pain With Transformative Possibilities, Richard B. Hovey

Patient Experience Journal

This personal narrative explores the experiences of pain metaphorically as a gift. The intention of this article is to offer alternative ways to reflect on pain, life and taking risks to move from health literacy toward health agency with help. I describe my approach to decision making using the hermeneutic wager which provides a means to imagine possibilities while mindfully assessing risk. Learning to manage pain and learning to live well with pain is a gift that we are not always aware is within our grasp.

Original Parts: Aging And Reckoning With Cystic Fibrosis Related Kidney Disease, Alexandra Ch Nowakowski

Patient Experience Journal

Kidney disease increasingly impacts people with cystic fibrosis (CF) as adult patients continue to survive longer. Yet the literature on CF related kidney disease focuses little on amplifying the voices of people aging with the condition. This article presents perspectives on CF related kidney disease from a medical sociologist who is themselves managing these issues. It (1) gives an overview of relevant literature and trends in epidemiological data on kidney disease and CF, (2) details the author’s own process of adjusting to progressive changes in renal function, and (3) outlines opportunities for clinicians to make a positive impact for patients …

The Sherpa Meets Maslow: Medicine And The Hierarchy Of Needs, Rana Lee Adawi Awdish Md Fccp

Patient Experience Journal

A critical care physician returning to medicine after her own critical illness experiences a crisis of orientation. She finds she can no longer serve as the Voice of Medicine. She replaces the former construct with a more humble model, in which the physician serves as an intermediary. She equates this new role to that of the Sherpas of Nepal. Maslow’s hierarchy of needs forms the mountain, as she reimagines her role in her patients’ lives.

The Consumer Has Spoken: Patient Experience Is Now Healthcare’S Core Differentiator, Jason A. Wolf Phd

Patient Experience Journal

In just a few days we will celebrate Patient Experience Journal’s (PXJ) 4^th anniversary since our inaugural publication. In these 4 short and quick years we have seen 163 articles published in our first four volumes that have stirred a significant focus on building the evidence base in patient experience. Not only has PXJ served as the central clearing house for thoughtful research, measurable cases, and insightful narratives, but it also has reinforced the breadth and depth of what patient experience truly encompasses. This integrated view was reinforced by the very voices of healthcare’s consumers in The Beryl Institute’s …

Medical School Watercooler Newsletter - March 25, 2018, Lindsey Lyle

Watercooler Newsletter

This is the March 25, 2018 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• Dr. Lammers Named AGS Clinician of the Year
• Greek Community Plants Tree in Hippocrates Park
• Register Now: 16th Annual Sickle Cell Regional Conference
• Mark Your Calendar: 2018 Gumbo Chili Showdown

Investigating The Synergistic Effects Of Two Curcuminoids And Cisplatin On Cancer Cell Reactive Oxygen Species, Matthew Millay

Mahurin Honors College Capstone Experience/Thesis Projects

Cisplatin is an anticancer drug which can cause the production of reactive oxygen species (ROS) that kill cancer cells. Curcumin is a naturally occurring plant compound that can increase ROS levels in cancer cells and enhance the activity of cisplatin against cancer, but it exhibits poor bioavailability. We investigated whether two synthetic curcumin analogs (curcuminoids), EF-24 and CLEFMA, with anti-cancer activity and improved bioavailability, increased cisplatin’s effect against cancer. A spectrophotometric fluorescent ROS assay was used to determine if cisplatin, the curcuminoids or combinations of cisplatin with a curcuminoid affected the level of ROS in the A549 non-small cell lung …

A 6-Week Hip Muscle Strengthening And Lumbopelvic-Hip Core Stabilization Program To Improve Pain, Function, And Quality Of Life In Persons With Patellofemoral Osteoarthritis: A Feasibility Pilot Study., Lisa T. Hoglund, Laura Pontiggia, John D. Kelly

Department of Physical Therapy Faculty Papers

Background: Patellofemoral joint (PFJ) osteoarthritis (OA) is prevalent in middle-aged and older adults. Despite this, there are minimal studies which have examined conservative interventions for PFJ OA. Weakness of proximal lower extremity muscles is associated with PFJ OA. It is unknown if a hip muscle strengthening and lumbopelvic-hip core stabilization program will improve symptoms and function in persons with PFJ OA. This study examined the feasibility and impact of a 6-week hip muscle strengthening and core stabilization program on pain, symptoms, physical performance, peak muscle torques, and quality of life in persons with PFJ OA.

Methods: Ten females with PFJ …

Integrative Annotation And Knowledge Discovery Of Kinase Post-Translational Modifications And Cancer-Associated Mutations Through Federated Protein Ontologies And Resources., Liang-Chin Huang, Karen E Ross, Timothy R Baffi, Harold J. Drabkin, Krzysztof J Kochut, Zheng Ruan, Peter D'Eustachio, Daniel Mcskimming, Cecilia Arighi, Chuming Chen, Darren A Natale, Cynthia Smith, Pascale Gaudet, Alexandra C Newton, Cathy Wu, Natarajan Kannan

Faculty Research 2018

Many bioinformatics resources with unique perspectives on the protein landscape are currently available. However, generating new knowledge from these resources requires interoperable workflows that support cross-resource queries. In this study, we employ federated queries linking information from the Protein Kinase Ontology, iPTMnet, Protein Ontology, neXtProt, and the Mouse Genome Informatics to identify key knowledge gaps in the functional coverage of the human kinome and prioritize understudied kinases, cancer variants and post-translational modifications (PTMs) for functional studies. We identify 32 functional domains enriched in cancer variants and PTMs and generate mechanistic hypotheses on overlapping variant and PTM sites by aggregating information …

Wearable Sensors Outperform Behavioral Coding As Valid Marker Of Childhood Anxiety And Depression, Ellen Mcginnis, Ryan Mcginnis, Jessica Hruschak, Emily Bilek, Ka Ip, Diana Morelen, Jamie Lawler, Kate Fitzgerald, Katherine Rosenblum, Maria Musik

ETSU Faculty Works

There is a significant need to develop objective measures for identifying children under the age of 8 who have anxiety and depression. If left untreated, early internalizing symptoms can lead to adolescent and adult internalizing disorders as well as comorbidity which can yield significant health problems later in life including increased risk for suicide. To this end, we propose the use of an instrumented fear induction task for identifying children with internalizing disorders, and demonstrate its efficacy in a sample of 63 children between the ages of 3 and 7. In so doing, we extract objective measures that capture the …

Thalamocortical Processing Of Temporal Cues In Sounds, Kasey Smith

Honors Scholar Theses

The ability of the brain to extract meaningful information from complex sounds is what allows mammals to understand species-specific communication as well as important environmental cues such as the sound of water or of potential predators or prey. The auditory cortex of humans and other mammals contains multiple cortical regions that unique sensitivities to both spectral and temporal sound cues. This discourse will explore three main factors proposed to determine these distinct processing capabilities in regard to temporal sound cues; the distribution of glutamate transporters in the thalamus, the architecture of afferent pathways between the thalamus and auditory cortex, and …

Dosimetric Feasibility Of 4dct-Ventilation Imaging Guided Proton Therapy For Locally Advanced Non-Small-Cell Lung Cancer, Qijie Huang, Salma K. Jabbour, Zhiyan Xiao, Ning Yue, Xiao Wang, Hongbin Cao, Yu Kuang, Yin Zhang, Ke Nie

Health Physics and Diagnostic Sciences Faculty Research

Background The principle aim of this study is to incorporate 4DCT ventilation imaging into functional treatment planning that preserves high-functioning lung with both double scattering and scanning beam techniques in proton therapy. Methods Eight patients with locally advanced non-small-cell lung cancer were included in this study. Deformable image registration was performed for each patient on their planning 4DCTs and the resultant displacement vector field with Jacobian analysis was used to identify the high-, medium- and low-functional lung regions. Five plans were designed for each patient: a regular photon IMRT vs. anatomic proton plans without consideration of functional ventilation information using …

Knowledge Disparities In Diabetes Mellitus Among Undergradute College Students: An Exploratory Study, Caroline Duffy

Honors College Theses

The primary goal of this research study is to examine the knowledge disparities in diabetes mellitus of health related and non- health related undergraduate majors at Georgia Southern University. The Newest Vital Sign tool is used to assess health literacy between majors. Health related majors will have a higher health literacy score. The research questions to be investigated are (a). do non-health related majors lack an understanding of diabetes mellitus and (b). do all college students have adequate health literacy. With the findings, health education and promotion programs can be established and directed towards the appropriate population.

Associations Between Feeding Practices And Growth And Neurodevelopmental Outcomes, Barbara T. Do, Nellie I. Hansen, Carla Bann, Rebecca L. Lander, Shivaprasad S. Goudar, Omrana Pasha, Elwyn Chomba, Sangappa M. Dhaded, Vanessa R. Thorsten, Jan L. Wallander, Fred J. Biasini, Richard Derman, Robert L. Goldenberg, Waldemar A. Carlo

Global Health Articles

Background

Feeding practices over the first several years of a child’s life can critically influence development. The purpose of this study was to examine associations between feeding practices and growth and neurodevelopmental outcomes at 36 months of age among children from low- and low-middle-income countries (LMIC).

Methods

We conducted a secondary analysis using data collected from children in India, Pakistan, and Zambia who were enrolled in a randomized controlled trial of a home-based early development intervention program called Brain Research to Ameliorate Impaired Neurodevelopment Home-based Intervention Trial. Qualitative dietary data collected at 36 months was used to assess the modified …

Open Cycle: Forecasting Ovulation For Family Planning, Karen Clark, Mridul Jain, Araya Messa, Vinh Le, Eric C. Larson

SMU Data Science Review

Abstract: Forecasting the length and different phases of a woman’s menstrual cycle, especially ovulation, is an important aspect of family planning. Predicting fertility has many uses in family planning including avoiding pregnancy and assisting couples in becoming pregnant. Past methods have focused on monitoring basal body temperature (BBT), cervical mucus changes, and hormonal levels to determine fertility. While these methods can provide an accurate prediction of ovulation these tests can become expensive, time-consuming, and do not provide prediction until after ovulation has occurred. In this paper, we compare conventional fertility assessment that is based on a rule known as “three-over-six” …

Biomechanical Assessment Of The Preperitoneal Hernial Repair By A Bipedicled External Oblique Aponeurotic Flap: Mobility Of The Floor Of The Inguinal Canal, Adel K. Barsoum, Mohamed M. Moneer, Soheir S. Makarem

Journal of Medicine in Scientific Research

Introduction Development of indirect inguinal hernias through the inguinal canal is usually prevented by the shutter and the sphincteric mechanisms, which are known to be destroyed by almost all anterior herniorrhaphies. Objective A new preperitoneal repair, which uses a bipedicled external oblique oponeurotic flap, has been recently introduced and was suggested to change the mechanics of this area. In this hernia repaires, the biomechanics of the inguinal region were assessed in healthy individuals and in patients with hernia after new repair and after other conventional anterior hernial repairs. Methods The study included 20 patients with inguinal hernias and 5 non-hernia …

The Efficacy Of Argon Plasma Coagulation In The Treatment Of Gastric Antral Vascular Ectasia In Mataria Teaching Hospital, Aisha El-Shimy, El Saied E. Shabaan, Tarek A. Fouad

Journal of Medicine in Scientific Research

Background Gastric antral vascular ectasia (GAVE) is characterized by mucosal and submucosal vascular ectasia. It may present with iron-deficiency anemia or gastrointestinal bleeding. Argon plasma coagulation (APC) may be used for treating GAVE. This study aims to evaluate the efficacy and safety of APC in the treatment of GAVE. Patients and methods A total of 30 patients with GAVE and in need of treatment for bleeding or anemia were treated with APC every 2 to 4 weeks until eradication of GAVE or cessation of the patient's initial symptoms. They were then followed up on a monthly basis for recurrence of …

Ovulation Induction In Women With Polycystic Ovarian Syndrome: Clomiphene Citrate Or Letrozole?, Mohamed Y. Elsemary, Osama S. El Taher, Waleed F. G. Mostafa

Journal of Medicine in Scientific Research

Objective The objective of this study was to determine first-line infertility therapy in polycystic ovarian syndrome (PCOS) and to compare between clomiphene citrate (CC) and aromatase inhibitors (letrozole) as the standard treatment. Patients and methods This is a prospective randomized study. The study was conducted at El-Galaa Assisted Reproduction Unit, El-Galaa Maternity Teaching Hospital, Cairo, Egypt. Eighty-eight women with PCOS were randomized into two groups. Rotterdam criteria were used to define PCOS: oligomenorrhea less than or equal to 8 menses/year plus either PCOS on ultrasound or clinical/biochemical hyperandrogenism, with the exclusion of other causes. Forty-four patients were randomized to the …

Serum Antimullerian Hormone Before And After Laparoscopic Excision Of Ovarian Endometrioma, Hossam El-Din Mahmoud, Osama S. El Taher, Rania H. Aly, Waleed F. G. Mostafa, Yousef M. Elsemary

Journal of Medicine in Scientific Research

Background Surgery of ovarian endometrioma may have a detrimental effect on ovarian reserve. This study aims to evaluate the effect of laparoscopic cystectomy on serum antimullerian hormone (AMH) in patients with endometrioma. Materials and methods A prospective study was performed at El-Galaa Maternity Teaching Hospital where 60 women with endometriomas underwent laparoscopic cystectomy. Serum AMH, follicle-stimulating hormone (FSH), luteinizing hormone, estradiol, and antral follicle count (AFC) were measured preoperatively and at 3 months postoperatively. Outcome measures The ovarian reserve was measured based on the change of AMH level before and after surgery. Moreover, the secondary end point was to detect …

Identification Of Different Bacterial Species Isolated From Infected Renal Stones And Evaluation Of Its Uricolytic Activity, Aisha El-Shimy, Azza Omran, Emad El-Tair, Hala I. Mohamed, Iman Kamel

Journal of Medicine in Scientific Research

Background Nephrolithiasis remains a public health problem around the world, affecting up to 20% of the population. There are many risk factors that increase one's susceptibility to kidney stone formation. These include specific food, urinary tract infection, kidney disorders, and metabolic disorder. Also, some people with a family history of kidney stones may be more susceptible to develop stones. Objective The aim was to isolate, purify, and identify bacteria from urinary stones. Also, determine the most bacterial isolate secreting uricase enzyme. Patients and methods A total of 100 cases were included in the study (66 men, 34 women) at the …

Value Of Toll-Like Receptor 3 (Tlr3) In Chronic Kidney Disease Patients With Hepatitis C Virus Infection, Aisha El-Shimy, El-Saied Shabaan, Hala Ibrahim, Iman Kamel, Tarek Fouad

Journal of Medicine in Scientific Research

Background Hepatitis C virus (HCV) infection is a severe public health problem with a worldwide predominance of 3%. An estimated 5–20% of infected patients develop cirrhosis annually, and 1–4% of them develop hepatocellular carcinoma. In Egypt, the prevalence of HCV antibody and HCV RNA are 10.0 and 7.0%, respectively, in the 15–59 years age group. In children of 1–14 years old, the prevalence of HCV antibody and HCV RNA are 0.4 and 0.2%, respectively. HCV infection is a cause of chronic kidney disease (CKD) and results in a significant problem in hemodialysis (HD) patients. Toll-like receptors (TLRs) might have an …

Effect Of Kinesio Taping Therapy On Waist Circumferences In Postpartum Women, Maha M. Mady

Journal of Medicine in Scientific Research

Objective The study was designed to examine the effect of Kinesio taping (KT) on abdominal circumferences in postpartum women with or without diastasis of rectus abdominus muscles (DRAM). Participants and methods A total of 26 women at 8 weeks postpartum, their age ranged from 25 to 35 years, their BMI was between 26.6 and 38.2 kg/m², suffering from increasing abdominal circumferences with or without DRAM, were referred from the outpatient clinic of the Gynecological Department of Shibeen El-Kom Teaching Hospital, All women received KT therapy on the abdomen. The treatment was applied for 4 consecutive weeks. Evaluation was …

Evaluation Of Nutrition Intake Of Football Players, Heba S. Abdelhaliem, Hoda M. El Gezrey

Journal of Medicine in Scientific Research

Introduction Despite football being the most popular sport in Egypt, most players do not know their needed nutritional requirements. The metabolic rate and energy consumption increased dramatically in football players. Thus, nutrition plays a significant role in improving the performance and the quality of life for these players. Objective This study aimed to assess the nutritional status of 50 football players aged between 15 and 19 years in Gomhorya Club – Menoufia. Participants and methods Dietary intake was evaluated for 7 days by using dietary assessment tools (24-h recall). This data was used to determine energy, macronutrients, micronutrients, and fiber. …

Evaluation Of Oxytocin And Serotonin Levels In Autism Spectrum Disorder, Amal El-Ramly, Azza Samy, Eman Soliman, Golnar Oteify

Journal of Medicine in Scientific Research

Objective Autism spectrum disorder (ASD) is a complex neurological and developmental disorder that affects how a person acts and interacts, communicates with others, and learns. Endocrine and neuropeptide factors are some among the list of possible etiologic or predisposing contenders. Abnormalities in the brain serotonin system are reported in ASD, including evidence of altered serotonin synthesis and receptor binding, as well as dystrophic serotonergic axons. Blood oxytocin levels are also a focus of ASD research. This work aimed to assess oxytocin and serotonin levels as biomarkers in individuals with ASD. Participants and methods Serotonin and oxytocin levels, as biochemical parameters …

Outcome Of Cochlear Implantation In Children With Enlarged Vestibular Aqueduct (Eva) And Mondini Dysplasia (Incomplete Partition Type Ii), Abir Omara, Amr Younes, Azza Sami, Ihab Sefein, Iman Elrouby, Soha Hamada

Journal of Medicine in Scientific Research

Background Congenital inner ear abnormality is a major cause of sensorineural hearing loss in children, about 20% of children with congenital sensorineural hearing loss (SNHL) have associated malformations of the temporal bone, and increased experience in cochlear implantation has led to more children with abnormal cochleo-vestibular anatomy submitted to this procedure. Aim To evaluate the outcome of cochlear implantation in cases with enlarged vestibular aqueduct (EVA) and Mondini deformity (incomplete partition type II) following cochlear implantation and comparing the results with cochlear implant cases without inner ear anomalies. Patients and methods 69 children all less than 6 years of age, …