Medicine and Health Sciences Commons^™

Beetroot Juice Supplementation Lowers Oxygen Cost Of Vigorous Intensity Aerobic Exercise In Trained Endurance Athletes, N. Ashton, E. Lind, J. Fiddler, R. Fiddler

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.

The Relationship Between Waist Circumference And Anaerobic Power Output In College Students, C. Appleman, C. Croall, J. Andreacci

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.

Case Study: Monitoring Sleeping Patterns Of A Boy With Duchenne Muscular Dystrophy And His Caregivers, J. Anning, M. Feltman, N. Little, Z. Zhu, A. Kelleher, R. Bendixen

International Journal of Exercise Science: Conference Proceedings

Please see the pdf version of the abstract.

El Salvador: Gun Violence, Sofia Wajner

Global Issues in Public Health

El Salvador, a country about the same size as the U.S’s New Jersey and a population of over six million people, has a death rate of 5.8 per 1,000. Even after going to war in the 1980s and 1990s, El Salvador is still riddled with everyday gun violence. Due to severe gang activity, the death toll has skyrocketed and police interjection only makes it worse. The leftist government of President Salvador Sánchez Cerén, has opposed negotiations and moved gang leaders into tighter-security prisons, moves that have intensified the climate of confrontation. Plans to combat gang and gun violence has made …

Ebola: Africa, James Goodwin

Global Issues in Public Health

In this paper, I talk about the Ebola Hemorrhagic Fever. Ebola is a rare virus that spreads through the immune system and can be fatal. Ebola is a pathogen from Africa, specifically West Africa. There has been almost 32,000 cases since 1976. Symptoms include, Fever, Headache, Muscle pain, Fatigue, Diarrhea, Vomiting, Stomach pain, and Bleeding/Bruising. Transmission happens during close or direct contact. World Health Organization has been making efforts to handle outbreaks such as the outbreak in 2014. World Health Organization mobilized and set up relief efforts. Education is a key idea for my thoughts on how we can intervene …

Ua61/16 Pre-Commencement Hooding & Awards Ceremony, Wku Physical Therapy

WKU Administration Documents

Pre-commencement program for Physical Therapy students.

Structural Variations In Circulating Lipopolysaccharide May Increase Severity Of Exercise-Induced Heat Illness, Skylar Wright

University Scholar Projects

Previous investigations at the Falmouth Road Race (FRR; Falmouth, MA) suggest that combined exercise, heat, and dehydration stress increase circulating lipopolysaccharide, associated binding proteins, and downstream immune signaling. Lipopolysaccharide (LPS), a component of gram-negative bacterial membranes, may be released into circulation from the gut with increased gastrointestinal permeability observed post-exercise. Circulating LPS activates host immune cell signaling that can lead to inflammatory responses that upregulate pro-inflammatory gene expression (eg TNF-α, IL-1β), which if unchecked, may lead to pathophysiology (eg cell pyroptosis, exertional heat stroke (EHS), and sepsis). While subjects of the 2015 FRR (n=30) had elevated core temperature …

The Importance Of Interdisciplinarity: Redefining The Health Belief Model, Ross F. Lordo

Senior Theses

Throughout academia, there lacks an existence of a commonly utilized multicomponent and interdisciplinary approach in understanding our outside world. This thesis provides an analysis of the current state of interdisciplinarity and the need to develop interdisciplinary theory. Through this effort, the researcher utilizes the health belief model as a framework that is severely limited in applicable scope due to its constructs. Contrastingly, systems theory and game theory are validated as examples of theories with an interdisciplinary nature. Through the coding of the literature pertaining to the qualitative characteristics of the health belief model, game theory and systems theory, guidelines in …

Designing A Calibration Set In Spectral Space For Efficient Development Of An Nir Method For Tablet Analysis, Md Anik Alam

Electronic Theses and Dissertations

Designing a calibration set is the first step in developing a spectroscopic calibration method for quantitative analysis of pharmaceutical tablets. This step is critical because successful model development depends on the suitability of the calibration data. For spectroscopic-based methods, traditional concentration based techniques for designing calibration sets are prone to have redundant information while simultaneously lacking necessary information for a successful calibration model. The traditional method also follows the same design approach for different spectroscopic techniques and different formulations, thereby lacks the optimizing capability to be technique and formulation specific.

A method for designing a calibration set in the Near …

An Ethical Framework For Organizational Resource Allocation For Patient Services In Health Care, Natalie Dick

Electronic Theses and Dissertations

Unanswered questions on how to allocate scarce resources in health care settings are often left to either bedside decision-making or, at best, the organizational policy level. Yet, there is little attention and no consensus on how organizational policy should address resource allocation in health care. An ethically sound framework is needed to guide policy development for resource allocation within health care organizations. In addition, a more comprehensive study of concepts tied to moral obligations of health care organizations is needed in terms of human rights, health disparities, and patient care quality. Until now, human rights literature has largely focused on …

Regional Microglia Are Transcriptionally Distinct But Similarly Exacerbate Neurodegeneration In A Culture Model Of Parkinson's Disease., Eric Wildon Kostuk, Jingli Cai, Lorraine Iacovitti

Department of Neuroscience Faculty Papers

BACKGROUND: Parkinson's disease (PD) is characterized by selective degeneration of dopaminergic (DA) neurons of the substantia nigra pars compacta (SN) while neighboring ventral tegmental area (VTA) DA neurons are relatively spared. Mechanisms underlying the selective protection of the VTA and susceptibility of the SN are still mostly unknown. Here, we demonstrate the importance of balance between astrocytes and microglia in the susceptibility of SN DA neurons to the PD mimetic toxin 1-methyl-4-phenylpyridinium (MPP

METHODS: Previously established methods were used to isolate astrocytes and microglia from the cortex (CTX), SN, and VTA, as well as embryonic midbrain DA neurons from the …

Ron And Kathy Assaf College Of Nursing - Nsu Dedication, Nova Southeastern University

NSU Books and Book Chapters

No abstract provided.

Education To Improve Patient Satisfaction And Outcomes In The Neurosurgical Patient, Tara Orgon Stamper

Doctor of Nursing Practice (DNP) Translational and Clinical Research Projects

Objective: Evidence based literature has illustrated that patient education can improve patient outcomes. In this translational study, a perioperative neurosurgery education bundle was implemented in patients undergoing elective cranial surgery to determine whether this patient centered education improved patient satisfaction, patient knowledge and patient outcomes. Method: This quality improvement study implemented an education bundle for elective cranial surgery patients both at a preoperative clinic visit and prior to discharge. Patients completed the Patient Interview Teaching Guide (PTIG) questionnaire and Client Satisfaction Questionnaire (CSQ-8) at the first postoperative visit. Results: Correlation statistics were conducted on demographic factors and patient knowledge and …

Key Components For An Ethics Consultation Curriculum, Joseph Bertino

Electronic Theses and Dissertations

Due to a lack of formal credentials for clinical ethics consultants, the professionalization of clinical ethics as a normative discipline in contemporary American health care is diminished amongst other health care professionals. While medical specialties, organizational leadership positions, and other miscellaneous health care occupations possess governing bodies that posit credentials that justify these roles, clinical ethics consultants lack a standard of competence. While this gap has been temporarily reconciled by individual employer criteria, a national standard that attempts to educate and demonstrate a clinical ethicist’s abilities does not exist. Still, various attempts have been made to establish a certification program …

The Relationship Between Perceptions Of Patient Safety Culture, Nurse Advocacy, And Nurse Sensitive Patient Outcomes, Margaret Dicuccio

Electronic Theses and Dissertations

The purpose of the study was to understand relationships between and among patient safety culture, nurse reported attitude toward patient advocacy and key patient outcomes. Nurses play an integral role in patient safety, providing care through constant interaction with the patient and clinical team. Advocating for patients is part of that role; however little research existed that explored how advocacy was related to the safety culture or specific patient outcomes.

A correlational cross-sectional design was chosen for this secondary data analysis. Correlation and regression models were applied to medical/surgical unit data from seven facilities within one hospital system. Sources of …

Melatonin-Micronutrients Osteopenia Treatment Study (Mots): A Translational Study Assessing The Effects Of Melatonin, Strontium Citrate, Vitamin D3 And Vitamin K2 On Bone Density, Bone Turnover Markers And Health-Related Quality Of Life In Postmenopausal Osteopenic Women Following A One-Year Double-Blind Randomized Placebo-Controlled Trial And On Osteoblast-Osteoclast Co-Cultures, Sifat Maria

Electronic Theses and Dissertations

Objective: The purpose of this study was to assess if a novel combination of melatonin and three other natural bone-aiding micronutrients: strontium citrate, vitamins D₃ and K₂ (MSDK) could improve bone health by modulating the activity of osteoblasts and osteoclasts in favor of balanced bone remodeling and by improving the overall health-related quality of life in postmenopausal osteopenic women.

Methods: The Melatonin-micronutrients Osteopenia Treatment Study (MOTS) is a translational research study that used both clinical and in vitro approaches to assess the efficacy of MSDK on bone health in women and to identify potential mechanisms for its effects. …

The Effect Of A Mindfulness Intervention On The Depression Symptoms Of Mothers In Treatment For An Opioid Use Disorder, Karen Alexander

Electronic Theses and Dissertations

BACKGROUND: Mothers in treatment for an opioid use disorder experience a high prevalence of depression which may influence their relationship with their child. In the general population, mindfulness-based parenting intervention has been seen in the literature to have a clear positive effect on maternal depression. No research has been published regarding the effect of mindfulness intervention on maternal depression of women in treatment for an opioid use disorder.

OBJECTIVES: To describe the characteristics of mothers in treatment for opioid use disorder, including depression and adverse childhood experiences, and to evaluate the characteristics associated with participation in a mindfulness intervention. Lastly, …

An Ethical Framework For Communication Of Prognosis In Pediatric Critical Care Medicine, Amanda Mattone

Electronic Theses and Dissertations

The focus of this dissertation is to create an ethical framework for communication of prognosis in the pediatric critical care setting. This dissertation argues that an ethical framework for communication of prognosis in the pediatric critical care setting is necessary because ethical communication transactions lead to better care for pediatric patients in critical care by enabling surrogate decision makers to make well-informed decisions. Moreover, a lack of effective communication skills can be detrimental to the patient. The need for such a framework is revealed by research indicating that physicians often lack the necessary education and skills for effective communication transactions …

Comparison Of Two Methods Of Pediatric Triage Education, Catherine Recznik

Electronic Theses and Dissertations

Introduction. The majority of pediatric emergency patients are seen in mixed-age emergency departments and triaged by general emergency nurses. Educational methods for teaching pediatric triage education to general emergency nurses have not been well studied, and previous studies of the use of the Emergency Severity Index in children have been performed primarily in centers that are high volume for pediatrics. Methods. A repeated measures, randomized crossover study comparing two different methods of pediatric triage education was conducted. Participants were general emergency triage nurses recruited from a general emergency department that is classified as low volume for pediatrics. Each participant was …

Dna Checkpoint And Repair Factors Are Nuclear Sensors For Intracellular Organelle Stresses-Inflammations And Cancers Can Have High Genomic Risks., Huihong Zeng, Gayani K Nanayakkara, Ying Shao, Hangfei Fu, Yu Sun, Ramon Cueto, William Y Yang, Qian Yang, Haitao Sheng, Na Wu, Luqiao Wang, Wuping Yang, Hongping Chen, Lijian Shao, Jianxin Sun, Xuebin Qin, Joon Y. Park, Konstantinos Drosatos, Eric T. Choi, Qingxian Zhu, Hong Wang, Xiaofeng Yang

Department of Medicine Faculty Papers

Under inflammatory conditions, inflammatory cells release reactive oxygen species (ROS) and reactive nitrogen species (RNS) which cause DNA damage. If not appropriately repaired, DNA damage leads to gene mutations and genomic instability. DNA damage checkpoint factors (DDCF) and DNA damage repair factors (DDRF) play a vital role in maintaining genomic integrity. However, how DDCFs and DDRFs are modulated under physiological and pathological conditions are not fully known. We took an experimental database analysis to determine the expression of 26 DNA DD

Neuromuscular Adaptations Following Slope Walking In Individuals Post-Stroke, Eric Akoopie, Brooke Conway Kleven, Trisha Koch

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: The excitability of the H-reflex pathway in the non-impaired nervous system can be augmented by altering the different parameters of a walking task, specifically slope. We sought to examine the adaptations in soleus H-reflex excitability and foot force control following an acute bout of upslope or downslope treadmill walking in people post-stroke compared to those who are non- impaired. Methods: We recruited 12 individuals with chronic post-stroke hemiparesis and 9 age-similar non- neurologically impaired individuals. Each subject was tested over 2 sessions separated by at least 7 days. For each session, subjects walked at a self-selected walking speed on …

Reliability And Validity Of Using A Mobile Application To Asses Knee Valgus In Healthy And Post-Anterior Cruciate Ligament Reconstruction Participants, Brenda Benson Deaver, Tyrel Nelson

UNLV Theses, Dissertations, Professional Papers, and Capstones

Objective: To examine the reliability and validity of using a movement analysis application (MAA) to measure knee valgus angle during three functional activities used to assess return-to-sport after ACL reconstruction (ACLR). Design: Reliability and validity study Setting: University laboratory Participants: Twelve ACLR participants with a non-contact mechanism of injury and 20 healthy individuals. Independent Variables: Each subject performed single-leg drop landing, single-leg hop, and 90º cut with simultaneous 3-dimensional (3D) motion capture and video recording in the frontal plane on an iPad. Main Outcome Measures: Peak knee valgus angle during the landing phase of each task was measured using a …

The Effect Of Standardized Photodocumentation On Coding Of Pressure Injuries, Brandon Bales, Alex Preciado, Angela Sandoval

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background and Purpose: Pressure injuries (PI) are prevalent and costly for hospitals. Hospitals implement different practices to accurately document PIs ranging from pen and paper to photodocumentation in electronic medical records (EMRs). In some instances, PIs that have been documented are not coded for billing and reporting. The purpose of this study is to determine if different documentation practices affect the number of coded PIs. Methods: Counts of coded PIs were collected from 2011- 2017 from two hospitals: a 500-bed acute care hospital (ACH) and a 42-bed acute rehabilitation hospital (ARH). A series of PI documentation practices were implemented over …

Individuals With Recurrent Low Back Pain Exhibit Significant Changes Of Paraspinal Muscle Performance After Lumbar Multifidus Intramuscular Fine Wire Electrode Insertion, Anthony Duong, Vincent Dinglasan, Russell Totten

UNLV Theses, Dissertations, Professional Papers, and Capstones

STUDY DESIGN: Case control study. BACKGROUND: Recurrent low back pain (RLBP) is associated with paraspinal muscle dysfunction. Intramuscular electromyography (EMG) is a common tool for studying activation of the deep lumbar paraspinal muscles such as multifidi muscles, but it is currently currently unclear how muscle performance and activation are affected by the pain and micro-injury associated with intramuscular fine-wire electrode (IFWE) insertion and how it interacts with the presence of RLBP. OBJECTIVES: The purpose of this study was to examine how IFWE insertion into the lumbar multifidus affects paraspinal muscle strength and endurance in subjects with and without RLBP. METHODS: …

Successful Patient Participation In Acute Hospital Physical Therapy, Jesse Kim, Joseph Fertitta, Patrick Williams

UNLV Theses, Dissertations, Professional Papers, and Capstones

Purpose/Hypothesis: Research has demonstrated that physical therapy plays a crucial role in patient recovery in the acute hospital setting. Despite known benefits, scheduled sessions do not always occur and are called nontreatment (NT) events. Reported NT ranges from 15% to 26% of scheduled sessions. Previous studies have found an association between NT and patient diagnosis as well as between NT and day of the week on which treatment was scheduled. Identifying additional factors that affect NT is important if therapists and administrators are to make improvements. The purpose of this study is to determine if an association exists between physical …

Patellofemoral Joint Stress During Uphill And Downhill Running In Healthy, Theresa French, Brooks Klein, Young Lee

UNLV Theses, Dissertations, Professional Papers, and Capstones

Subjects: Twenty recreational runners participated (mean age of 24.9 years). Methods: Kinematics and kinetics of the trunk and lower extremity were obtained at 3 conditions: level, 6° uphill, and 6° downhill, at a speed of 2.3 m/s. PFJ stress was determined using a biomechanical model that incorporates knee flexion angle and knee extensor moment as subject-specific input variables. The model output consisted of PFJ reaction force, PFJ stress, and PFJ contact area. One-way ANOVAs with repeated measures and post-hoc t-tests with a Bonferroni adjustment were used to compare outcome variables across the 3 conditions. Results: Peak PFJ stress during downhill …

Investigation Of The Cardiovascular Endurance Of Dance Majors, Arnold Huang, Ali Ross, Kelsey Taelour, Geneva Winters

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: College dancers have demonstrated low levels of cardiovascular endurance compared to other athletes, which could be one of the factors that leads to more fatigue and injuries during performance. The effects of an education session on cardiovascular endurance and on college dancers’ attitudes towards cardiovascular exercise outside of dance class have not been previously studied. Purpose: The purpose of this study was to use the accelerated three-minute step test to compare lower level and upper level college dancers’ cardiovascular endurance before and 2 months after an education session emphasizing fitness and exercise. Additionally, assessed were the dancers’ attitudes towards …

Giant Siliconoma Mimicking Locally Advanced Breast Cancer: A Case Report And Review Of Literature, Bryce Carson, Steven Cox, Hishaam Ismael

School of Medicine Faculty Publications and Presentations

Introduction: Silicone prosthetics are widely used for breast augmentation and reconstruction. These devices may extrude free silicone into surrounding tissue, stimulating a granulomatous foreign body reaction. The resulting mass can mimic breast cancer. Presentation of Case: 71 year old female with a history of a ruptured silicone implant presents with an enlarging left breast mass. Exam demonstrated and ulcerated, fungating mass with active infection. CT scan demonstrated a 23 × 15 cm mass involving the breast and chest wall with axillary lymphadenopathy. Preoperative biopsies were inconclusive and the patient underwent a modified radical mastectomy. Pathology demonstrated a siliconoma. Discussion: While …

Variables Affecting Latency Of Rats Running On A Maze, Divya Subramanian

Honors Scholar Theses

When rats are running on a maze, what factors affect their latency? This project examines how time of day of training and hunger levels of the rats affect how long they take to complete the sessions of a behavioral task. A training day consists of three sessions, each with 20 runs. I hypothesize that the rats’ performance will improve if they are trained later in the day, if they are hungrier, and in successive sessions.

Effects Of Heart Rate Variability-Guided Prescription On The Physiological Outcomes Of Crossfit Training, Nicholas B. Drake

Electronic Theses & Dissertations

Purpose: The purpose of this investigation is to determine the effectiveness of heart-rate variability as a monitoring and intensity-prescription tool for CrossFit.

Methods:Twenty-five recreational trained males and females were randomized into two groups, experimental (EXP) and control (CON) prior to the intervention. Prior to any assessments, all participants established a 14-day baseline period for their morning heart-rate variability. Both groups underwent pre-training assessment for work capacity, whole body strength, maximal oxygen consumption and body composition. All participants followed a 21-day training program followed by another week of testing, repeated twice. During the training, a rolling seven-day average of …