Medicine and Health Sciences Commons^™

The Death Debate: Penumbra Conundrum, Robert F. Johnson

Peer Reviewed Articles

Determination and declaration of death by neurologic criteria, brain death, is an established and legally accepted clinical practice with profound implications. Concerns regarding the accuracy of this diagnosis raise important clinical, ethical, and legal issues. A recent magazine article highlights these concerns by describing a poignant example of a patient meeting accepted clinical and ancillary testing criteria for brain death in the setting of post cardiac arrest hypoxic ischemic encephalopathy (CA-HIE). With continuation of ventilatory and nutritional support, this patient not only survived but over time demonstrated findings that were no longer consistent with brain death. Offered here is a …

School Of Nursing News, Georgia Southern University

Nursing: News & Publications (2013-2023)

• Georgia Southern nursing students receive 2018 Abbie Lorene DeLoach Memorial Scholarships

Emerging Themes In Coping With Lifetime Stress And Implication For Stress Management Education, Asrat G. Amnie

Publications and Research

Background: Adults with adverse childhood experiences and exposure to adverse life events experience a diverse array of physical, mental, and social health problems across their lifespan. Adult exposure to emotional trauma, physical injury, or other adverse life events may result in the development of post-traumatic stress and post-traumatic stress disorder. Understanding individuals’ response to stress and their coping strategies is as important as the stimulus or the causes of the stress for effective stress management interventions.

Methods: This is a mixed quantitative and qualitative online survey study which explores the coping strategies to stress in adults with adverse childhood experiences …

A Qualitative Exploration Ofdoctors And Nurses Experienceson The Management Of Tubercu-Losis And Hiv Co-Infection In Atuberculosis-Hiv High Burdencommunity In Northernkwazulu-Natal, South Africa, Mbuso Mabuza, Constance Shumba

School of Nursing & Midwifery, East Africa

South Africa is faced with a huge challenge of addressing the high burden of tuberculosis-human immune virus (TBHIV) co-infection, and this challenge is more pronounced in the province of KwaZulu-Natal which has one of the highest burdens of TB-HIV co-infection in the world. The study explored the experiences of doctors and nurses with regard to the management of tuberculosis and HIV coinfection in a TB-HIV high burden community in northern KwaZulu-Natal, South Africa. The particular focus was to provide insight and to inform policy and programme development for effective management of TB-HIV co-infection in the TB-HIV high burden community of …

Medical Apartheid: A Book Review, Carmen Kennedy

Themis: Research Journal of Justice Studies and Forensic Science

No abstract provided.

Exposure Implications Of Electronic Cigarette Surface Contamination, Cheri Marcham, Evan Floyd

Publications

• Retention of nicotine on porous, hydrophilic surfaces can be long enough to allow reaction with ambient gases to form TSNAs (tobacco specific nitrosamines).

• Potential risk for third-hand exposure over time appears to be low, but should be verified by longer term studies.

• Use of ECs (electronic cigarettes) should be consistent with traditional cigarette smoking policies.

Antimicrobial Peptide Ll-37 And Recombinant Human Mannose-Binding Lectin Express Distinct Age- And Pathogen-Specific Antimicrobial Activity In Human Newborn Cord Blood In Vitro, Annette Scheid, Ning Li, Carleen Jeffers, Francesco Borriello, Sweta Joshi, Al Ozonoff, Matthew Pettengill, Ofer Levy

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Background: There is a need to prevent and treat infection in newborns. One approach is administration of antimicrobial proteins and peptides (APPs) such as LL-37, a membrane-active cathelicidin antimicrobial peptide, and mannose-binding lectin (MBL), a pattern-recognition protein that binds to microbial surface polysaccharides resulting in opsonization and complement activation. Low plasma/serum levels of LL-37 and of MBL have been correlated with infection and exogenous administration of these agents may enhance host defense. Methods: The antimicrobial activity of LL-37 (15 µg/ml) or rMBL (0.5, 2 and 10 µg/ml) was tested in hirudin-anticoagulated preterm and term human cord blood (N = 12-14) …

Free From The Threat Of Huntington’S Disease, Our 'Miracle Baby' Turns 18, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.

Medical School Watercooler Newsletter - May 20, 2018, Lindsey Lyle

Watercooler Newsletter

This is the May 20, 2018 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• Hughes Named Assistant Director of Marketing and Communications
• Med School Café – Expert Advice for the Community
• USA Alumnus Named President-Elect of State Medical Association
• USA Medical Student Receives ASTRO Minority Summer Fellowship Award

In Vivo Application Of Proton-Electron Double-Resonance Imaging, Shun Kishimoto, Murali C. Krishna, Valery V. Khramtsov, Hideo Utsumi, David J. Lurie

Clinical and Translational Science Institute

Significance: Proton-electron double-resonance imaging (PEDRI) employs electron paramagnetic resonance irradiation with low-field magnetic resonance imaging so that the electron spin polarization is transferred to nearby protons, resulting in higher signals. PEDRI provides information about free radical distribution and, indirectly, about the local microenvironment such as partial pressure of oxygen (pO2), tissue permeability, redox status, and acid-base balance. Recent Advances: Local acid-base balance can be imaged by exploiting the different resonance frequency of radical probes between R and RH+ forms. Redox status can also be imaged by using the loss of radical-related signal after reduction. These methods require optimized radical probes …

In Vivo Electron Paramagnetic Resonance: Radical Concepts For Translation To The Clinical Setting, Valery V. Khramtsov

Clinical and Translational Science Institute

Electron paramagnetic resonance (EPR)-based spectroscopic and imaging techniques allow for the study of free radicals—molecules with one or more unpaired electrons. Biological EPR applications include detection of endogenous biologically relevant free radicals as well as use of specially designed exogenous radicals to probe local microenvironments. This Forum focuses on recent advances in the field of in vivo EPR applications discussed at the International Conference on Electron Paramagnetic Resonance Spectroscopy and Imaging of Biological Systems (EPR-2017). Although direct EPR detection of endogenous free radicals such as reactive oxygen species (ROS) in vivo remains unlikely in most cases, alternative approaches based on …

In Vivo Molecular Electron Paramagnetic Resonance-Based Spectroscopy And Imaging Of Tumor Microenvironment And Redox Using Functional Paramagnetic Probes, Valery V. Khramtsov

Clinical and Translational Science Institute

Significance: A key role of the tumor microenvironment (TME) in cancer progression, treatment resistance, and as a target for therapeutic intervention is increasingly appreciated. Among important physiological components of the TME are tissue hypoxia, acidosis, high reducing capacity, elevated concentrations of intracellular glutathione (GSH), and interstitial inorganic phosphate (Pi). Noninvasive in vivo pO2, pH, GSH, Pi, and redox assessment provide unique insights into biological processes in the TME, and may serve as a tool for preclinical screening of anticancer drugs and optimizing TME-targeted therapeutic strategies. Recent Advances: A reasonable radiofrequency penetration depth in living tissues and progress in development of …

Digital Tools For Managing Different Steps Of The Systematic Review Process, Wendy Wu, Katherine Akers, Ella Hu, Alexandra Sarkozy, Patricia Vinson

Library Scholarly Publications

Performing systematic reviews (SR) and meta-analyses is an arduous and time-consuming process that involves not only comprehensive literature searching but also record de-duplication, title/abstract and full-text screening, data extraction, quality assessment, statistical analysis, data visualization, report writing, and the creation of a bibliography. In the past several years, several digital tools and software have become available to facilitate different steps of the systematic review process. However, due to the growing number of tools, it can be difficult for systematic reviewers to make fully informed decisions about which tool(s) to use. Here, we (1) compile a comprehensive list of currently available …

Antioxidants And Cancer: Theories, Techniques, And Trials In Preventing Cancer, Gloria M. Calaf, Francisco Aguayo, Consolato M. Sergi, Angeles Juarranz, Debasish Roy

Publications and Research

No abstract provided.

Hospital Libraries: A Path Forward, Basia Delawska-Elliott, Wm. Brian Elliot

Books, Presentations, Posters, Etc.

Program Description: Despite our profession’s constant evolution to address the changing needs of our users, many health sciences libraries, particularly hospital libraries, are under scrutiny by their institutions. Many of these libraries are facing closure. In fact, a recent study of health sciences library closings [Schwartz, Elkin 2017] found that from 1989-2006 approximately 23-34% of US health sciences libraries closed. Furthermore, between 2011 and 2015, 613 libraries closed, for an average of 115 closings per year [Thibodeau, Funk 2009]. But why? What was the rationale for these closings? Was the decision based solely on economic reasons, or were there other …

Effectiveness Of Early Postpartum Follow-Up On Breastfeeding Attrition, Joyce Bouknight-Gant

Doctor of Nursing Practice (DNP) Translational and Clinical Research Projects

This quality improvement project evaluated the effectiveness of early postpartum follow-up in decreasing breastfeeding attrition rates among postpartum mothers in the first three weeks after delivery. Of special interest is the ability to identify possible differences among maternal characteristics such as age, ethnicity, race or parity. Although the benefits of breastfeeding are widely known and breastfeeding in the United States continues to rise, the breastfeeding rates among African-American women and other races remain lower with a notable significant gap. As of 2013, African American mothers lagged behind their white and Hispanic counterparts in the practice by at least 20 percentage …

Hematological Changes In Response To A Drastic Increase In Training Volume In Recreational Cyclists, Jessie Axsom

James Madison Undergraduate Research Journal (JMURJ)

Changes in blood volume contribute to improvement in oxygen utilization (VO2max) with chronic endurance exercise training. Although hematological changes resulting from long-term endurance training have been well documented, it has not been well established whether an increased volume of endurance training preferentially affects plasma volume or red blood cell volume. To answer this question, I studied seven female and four male recreational cyclists before and after exposure to drastic increases (632%) in training volume. Following the 10-week training period, the mean hematocrit (Hct) of the 11 subjects who completed the study significantly (p0.05) correlated with the change in self-reported weekly …

A Modified Method Of High Molecular Weight Adsorbable Organic Chlorine Measurement In Saline Water: Dialysis Pretreatment, Jiajian Liu, Li Ling, Yi Li, Chao Wang, Chii Shang

Faculty of Science & Technology (THEi)

Adsorbable organic halogen is a mean to quantify total organic halogen, which is an important toxicity indicator in disinfection byproduct studies. However, quantification of low concentrations of adsorbable organic chlorine (AOCl) formation in seawater chlorination using the USEPAMethod 9020Bwas found inaccurate due to the presence of high concentrations of chloride. In this study, a dialysis-based pretreatment techniquewas proposed, optimized and adopted to eliminate the interference of chloride in quantifying low concentrations of AOCl inseawater. A volumetric ratio of dialysis samples to continuous-flow deionized water at 1:1200 was found sufficient to remove over 99% of chloride. As a result, chloride to …

Imagination Station: Activating Creativity In Children With Disabilities, Allison Dukes

Expressive Therapies Capstone Theses

Play is a major topic of conversation when discussing childhood development is associated with creativity and imagination. Although there has been some research involving the creative process amongst children, little has been explored in regards to expressive arts as a technique to further current studies on play. This paper presents a combined method of intermodal expressive arts therapies and play therapy techniques to aid in the fostering of creativity within children with disabilities by utilized the theoretical framework provided by the Expressive Therapies Continuum (ETC). A current review of literature on the ETC, cognitive functions, and expressive arts modalities is …

How Can The Attunement Needs Of Children With Disorganized Attachment Styles Be Supported Through Expressive Arts Therapy?, Jayne Paley

Expressive Therapies Capstone Theses

Treatment strategies for school age children with disorganized attachment are not well established. This population exhibits a range of difficulties in social relationships and self-regulation. Additionally, children with disorganized attachment generally rely on defense mechanisms and present with other comorbid conditions, adding to the complexity of treatment. This paper explores current research and theories about disorganized attachment and then, on the basis of evidence provided throughout this paper, proposes the concept of attunement needs in relation to working with children with disorganized attachment. The attunement needs described in this paper, derived from the literature, include safety/security, control/power, consistency, affective release, …

Thermoregulatory Dysfunction In Multiple Sclerosis, Dustin R. Allen

Applied Physiology and Wellness Theses and Dissertations

Multiple sclerosis (MS) is a progressive neurological disease of the central nervous system (CNS) affecting an estimated 2.3 million people worldwide. Marked by lesions in the brain and spinal cord, MS leads to conduction abnormalities in the CNS. Evidence suggests ~60% of individuals with MS experience temporary worsening of their symptoms upon exposure to heat. Adding complexity, observational evidence suggests these individuals exhibit reduced thermoregulatory responses in upon increases in core temperature. Consequently, these individuals face a vicious cycle of heat sensitivity and thermoregulatory dysfunction, substantially impacting their quality of life. With this in mind, our lab is dedicated to …

Exploring Self-Injury: An Art-Based Approach To Cultivating Empathy And Understanding In Mental Health Professionals, Dana Wyss

Expressive Therapies Dissertations

Self-injury greatly affects individuals, their families, and the mental health professionals who provide their care. This art-based research investigates the impact of clients’ self-injury on mental health professionals. It addresses four research questions and applies a methodology that integrates body art, photography, poetry, and dialogue. Six participants (including the researcher) participated in three meetings wherein they artistically responded with temporary body art to two questions, sorted through their photographs, reviewed poetry created about their work, and discussed the study experience. The researcher navigated being a witness-researcher by personally and creatively engaging in the study.

The results present raw, distilled narratives, …

Art Therapy And The Person-Centered Approach: A Method For Breaking Down Creative Resistance With Dementia Patients, Kimberly Nelson

Expressive Therapies Capstone Theses

This Capstone explores the use of art therapy with a geriatric population on a psychiatric unit of a small, rural southern hospital. Most of the patients experience symptoms of dementia and are over the age of 55. Many patients presented with resistance to creative pursuits and this researcher utilized the person-centered approach to counter this “creative resistance”. In other words, the patients were met where they were at and accepted unconditionally, through empathy and congruence. The materials that were offered to this population were explored through the creative resistance as well, and a simple number two pencil produced successful results …

Self-Applied Touch To Promote Self-Regulation In Adolescent Males With Problem Sexual Behaviors: Development Of A Method, Nicole Krzeminski

Expressive Therapies Capstone Theses

Adolescents who have experienced problematic attachment relationships in infancy often have difficulty with self-regulation and therefore may cope using destructive means such as harmful sexual behavior. Self-regulation is the ability to calm the mind and body and manage emotions appropriately. Dance/movement therapy (DMT) may be a beneficial treatment tool for adolescents with problem sexual behaviors (PSB) to teach self-regulation techniques that may have not been developed due to early traumatic experiences. Self-applied touch is a DMT intervention that may assist individuals with self-regulation that was missed during critical developmental periods. This Capstone project implemented a self-applied touch warm-up with six …

Patterns Of Stigma: Dance Therapy As An Intervention Method For People Living With Hiv, Elizabeth Jezorski

Expressive Therapies Capstone Theses

This paper will explore the impact that dance movement therapy (DMT) has for people living with HIV. DMT is an evidence-based modality that engages the body in the therapeutic process for individuals and groups in various settings. DMT has been shown to increase social connectedness, empathy and body awareness in many populations; however, there is a lack of research using DMT as an intervention for people with concealable stigma. Concealable stigma is an experience of oppression that can often be hidden or concealed. To explore this, four DMT sessions were implemented with people living with HIV. These sessions were analyzed …

A Dance/Movement Therapy Method For Improving Mood States Of Adolescent Girls In A Residential Treatment Center, Selena Coburn

Expressive Therapies Capstone Theses

The purpose of this study is to examine dance/ movement therapy (DMT) sessions as a method of intervention, through observing with Laban Movement Analysis (LMA) and Kestenberg Movement Profile (KMP) and recording shifting mood states in participants living in a residential treatment center. The participants are adolescent female clients age 13-17 years old. They have co-morbid diagnoses including depression, eating disorders, ADHD, histories of abuse and neglect, and oppositional defiant disorder. Laban Movement Analysis (LMA) and verbal check-ins are used to determine mood states before, during, and after a DMT session. Data is collected via observations made using a designated …

Mirroring, Social Learning And Dance Movement Therapy With Childhood Autism Spectrum Disorder: A Literature Review, Megan Fitzpatrick

Expressive Therapies Capstone Theses

The literature review investigated the use of mirroring to help develop emotional understanding through social learning with children diagnosed with Autism Spectrum Disorder (ASD). The research reviewed was used to further cognize how mirroring could give a child with ASD a better understanding of their own and others’ emotions through social learning. The findings revealed that mirroring could be an affective tool to build social awareness of emotions in children diagnosed with ASD. The mirror neuron system (MNS) is the area of the brain that assesses perception and production of movement creating an overlap. Using the idea of the mirror …

Integrating Expressive Therapies And Visual Literacy Skills In An Exceptional Children Classroom, Natalia Torres Del Valle

Expressive Therapies Capstone Theses

The method conducted in this thesis integrated museum education, exceptional children education, and expressive arts therapy practices. Objectives for implementing the method were to learn how to effectively address the unique needs within the exceptional children classroom, as well as to collaborate with the teacher to address those needs through expressive arts therapy and visual literacy approaches. In so doing, I wanted to examine the differences and similarities between museum education and expressive arts therapy and how they can work together to meet therapeutic goals. The method took place over four sessions; each session focused on a work of art …

Body Based Meditative And Mindfulness Practices For Veterans With Combat Related Ptsd, Jessica Steurer

Expressive Therapies Capstone Theses

This literature review investigates and examines how body based meditative and mindfulness practices can be an effective treatment method for Veterans with symptoms of combat-related posttraumatic stress disorder. Yoga Therapy and other Expressive Therapy modalities (Art, Music) have developed evidenced-based practices and supporting research for this treatment area. Dance Movement Therapy (DMT) has shown effectiveness when treating conditions Veterans often present with such as combat-related PTSD, Substance Abuse, Anxiety, and Stress. DMT is a modality that focuses on the integration of the mind and body. Veterans benefit from body-based practices because they help to focus on the present moment while …

A Dance Movement Therapy Warm Up Method In Bereavement Peer Support Groups For Children, Amanda Moffitt

Expressive Therapies Capstone Theses

Every year in the United States, millions of children experience the death of a parent (Owens 2008; Stikkelbroek, Prinzie, de Graaf, ten Have, and Cuijpers 2012). Parental death in childhood can lead to severe impairments in physical and mental health, as well as overall life satisfaction, because of the potential traumatic nature of the event (Li, Vestergaard, Cnattingius, Gissler, Bech, Obel, & Olsen, 2014; Marks, Jun, & Song, 2007; Perkins & Harris 1990). Children have previously been neglected in regards to grief theory and the traumatic experience such loss impacts children. Recently, research has demonstrated that self-regulation is instrumental in …