Medicine and Health Sciences Commons^™

What Influences Family Planning In Rural Pakistan: Franchised Service Provider And Community Health Worker Perspective, Waqas Hameed, Junaid-Ur-Rehman Siddiqui, Muhammad Ishaque, Sharmeen Hussain, Xaher Gul, Hina Najmi, Shehla Noorani, Ghulam Mustafa, Asma Balal

Community Health Sciences

Background: Pakistan has a low modern contraceptive prevalence rate, 26%, leading family planning (FP) programmes to explore partnerships with local private providers to improve access to quality FP services. This study aims to understand the socio-cultural and organizational factors that influence delivery of quality family planning services.
Methods: This qualitative study was conducted with private service providers and community health workers (CHW) in Marie Stopes Society's (MSS) social franchise network. A total of 31 providers and 28 CHWs from Sindh, Punjab, and Khyber Pakhtunkhwa provinces of Pakistan were purposively selected for in-depth interviews. The study used thematic content analysis to …

An Uncommon And Elusive Cause Of Cerebral Venous Thrombosis, Farheen Niazi, Saadia Riaz

Pakistan Journal of Neurological Sciences (PJNS)

We present a case of of young 27year male who was admitted with history of headache and vomiting for one week. He was diagnosed as having dural sinus thrombosis of superior sagittal, right lateral, right sigmoid sinus. There was previous history of uveitis 6 months prior to it. All thrombophilia workup was negative except homocysteine levels were moderately high. He was also found to be having recurring genital and oral ulcers. Pathergy test was negative. His HLA B 51/5 testing came back positive. Final diagnosis of Bechet’s disease was made and responded well to long term steroids and Colchicine. A …

Metachronous Renal Ewing Sarcoma/Primitive Neuroectodermal Tumour In A Survivor Of Burkitt Lymphoma, Kumail Khandwala, Kiran Hilal, Zehra Fadoo, Khurram Minhas

Department of Radiology

We present a case of a 14-year-old girl who was diagnosed with Burkitt lymphoma in 2014. She was managed with chemotherapy and remained in remission for 3 years. On her surveillance imaging in 2017, a left-sided renal neoplastic mass was incidentally discovered. She underwent nephrectomy and pathology of the resected specimen revealed small cell tumour of the kidney with features favouring renal Ewing sarcoma/primitive neuroectodermal tumour. Molecular genetic analysis by fluorescence in situ hybridisation was performed which showed translocation of 22q12, thereby confirming the diagnosis. This is a rare secondary malignancy and an unusual association. This case highlights the importance …

An Analysis Of Self-Reported Suicide Attempts And Ideation In A National Sample Of Incarcerated Sex Offenders, Kseniya Katsman

Student Theses

Suicide is the leading cause of preventable death in US jails and prisons, with rates three to nine times higher than those of the general population. Although suicide in correctional settings has been recognized as a serious problem, the research on suicide among incarcerated individuals remains limited. While the majority of suicide risk factors may be common across all offender types, sex offenders may be at a particularly elevated risk. Specifically, sex offenders have been found to report high rates of hopelessness and depressive mood, which are known predictors of suicidal behavior, and approximately 14% of incarcerated sex offenders have …

Exploratory Study Of The Use Of Community Treatment Orders With Clients Of An Ontario Act Team, Magnus Mfoafo-M'Carthy, Cara Grosset, Carol A. Stalker, Irene Dullaart, Linda Mccoll Dr.

Lyle S. Hallman Social Work Faculty Publications

Community Treatment Orders (CTOs) have raised questions about coercion, lack of autonomy, and effectiveness in reducing hospitalizations and improving service users’ quality of life. This study examined the experiences of clients and clinicians when CTOs are used in combination with Assertive Community Treatment (ACT) in a recovery oriented approach. Eleven clients who were or had previously been on a CTO and eight ACT clinicians were interviewed. Although most clients had negative feelings about CTOs, some acknowledged their lives had improved. Clinicians reported that the decision to employ a CTO is sometimes debated within the team but they agreed that combining …

Ptsd Among Working Women In A Developing Country, Lung-Chang Chien, Taylor J. Fitch, Xiao Yu, Mohammad Monjural Karim, Hasanat Alamgir

Research Briefs

No abstract provided.

Experimentation In Homoeopathy: History And Prospects, Raj Manchanda

Indian Journal of Research in Homoeopathy

No abstract provided.

A Randomised Comparative Study To Evaluate The Efficacy Of Homoeopathic Treatment -Vs- Standard Allopathy Treatment For Acute Adenolymphangitis Due To Lymphatic Filariasis, Jaya Gupta, Raj Manchanda, Lipi Debata, Gupta Payal, Sujata Choudhary, Akshaya Prusty, Goutam Rakshit, Vikram Singh, Arvind Kumar

Indian Journal of Research in Homoeopathy

Objective: The primary objective of the study was to compare the effectiveness of homoeopathic treatment with standard allopathic regimen in acute ADL and secondary objective was to assess the reduction in frequency, duration and intensity of subsequent attacks, improvement of the quality of life of patients. Methods: The study was designed as a comparative randomized trial conducted from October 2012 to April 2014, on 112 patients at Regional Research Institute, Puri, Odisha. The ADL patients enrolled were randomized to receive either homoeopathic treatment or standard allopathic treatment for a period of six months. The outcome parameters used were ADL score …

Erratum: Book Review: Evidence Based Research Of Homoeopathy In Gynaecology, Ijrh Ijrh

Indian Journal of Research in Homoeopathy

No abstract provided.

An Assessment Of Methods Of Sampling And Characterizing Engineered Nanomaterials In The Air And On Surfaces In The Workplace, Maximilien Debia, Gilles L’Espérance, Cyril Catto, Philippe Plamondon, André Dufresne, Claude Ostiguy

Rapports de recherche scientifique

La surveillance des niveaux de contamination de l’air par des nanomatériaux manufacturés (NMM) est une démarche complexe qui présente plusieurs incertitudes et limites notamment : la présence simultanée de particules de dimensions nanométriques qui ne sont pas des NMM, l’absence d’instruments validés permettant une mesure en zone respiratoire et la multiplicité des indicateurs à apprécier. Certains organismes, dont l’Institut national de recherche et de sécurité (INRS) en France et l’Institut de recherche Robert-Sauvé en santé et en sécurité du travail (IRSST) au Québec soulignent aussi la nécessité de réaliser des prélèvements surfaciques afin d’attester la présence de dépôts …

Targeting Twist1 Through Loss Of Function Inhibits Tumorigenicity Of Human Glioblastoma., Andrei M Mikheev, Svetlana A Mikheeva, Liza J Severs, Cory C Funk, Lei Huang, José L Mcfaline-Figueroa, Jeanette Schwensen, Cole Trapnell, Nathan D Price, Stephen Wong, Robert C Rostomily

Articles, Abstracts, and Reports

TWIST1 (TW) is a bHLH transcription factor (TF) and master regulator of the epithelial-to-mesenchymal transition (EMT). In vitro, TW promotes mesenchymal change, invasion, and self-renewal in glioblastoma (GBM) cells. However, the potential therapeutic relevance of TW has not been established through loss-of-function studies in human GBM cell xenograft models. The effects of TW loss of function (gene editing and knockdown) on inhibition of tumorigenicity of U87MG and GBM4 glioma stem cells were tested in orthotopic xenograft models and conditional knockdown in established flank xenograft tumors. RNAseq and the analysis of tumors investigated putative TW-associated mechanisms. Multiple bioinformatic tools revealed significant …

One Pulmonary Lesion, 2 Synchronous Malignancies, Masooma Aqeel, Nevin Uysal Biggs, Timothy S. Fenske, Nagarjun Rao

Section of Cardiology

Introduction. Mantle cell lymphoma (MCL) comprises approximately 3% to 10% of all non-Hodgkin lymphomas. Although there is an increased risk for secondary malignancies after treatment among non-Hodgkin lymphomas survivors, a synchronous diagnosis of primary lung cancer arising in conjunction with lymphoma at the same site has rarely been reported. We report an unusual case of primary lung adenocarcinoma with coexistent MCL within the same lung lesion. Case Presentation. A 55-year-old female with newly diagnosed stage IV-B MCL was referred for workup of a right upper lobe cavitary lesion detected during lymphoma staging. A whole-body positron-emission tomography-computed tomography scan …

Association Of Tissue Vitamin D Receptor Expression With Breast Cancer Molecular Subtypes In Kenyan Women, Mutambuki Kimondo

Master of Medicine in Anatomic Pathology

Background: Previous studies have shown that reduced vitamin D receptor expression in breast cancer tissue is associated with worse disease outcomes. Furthermore, studies show that estrogen negative and triple negative breast cancer is associated with a poor prognosis and a low breast tissue vitamin D receptor (VDR) expression. Other studies also report that low serum vitamin D levels are associated with more aggressive breast cancer. Methods: This was a cross-sectional study with both a retrospective and a prospective arm. The retrospective part was nested within a larger study; previously constructed tissue microarray blocks (TMA) blocks were used for analysis of …

Cime Newsletter : June 2018, Cime

Centre for Innovation in Medical Education (CIME) Archives

- 13th AKU Ilizarov Course -Victoria
-Meet Our New Simulation Family Member
-Future Nurses and Doctors @ CIME
-Simulation in Action! -Basic Surgical Skills Workshop
-GI Endoscopy and ERCP Workshop
-Cardiology Survival Skills Workshop
-TED Talk by Sofia Babool, One of our Global Encounter students
-CIME Tours
-Clinical Simulation Educator Programme
-New Arrivals
-Breaking News!

Today - June 2018, Loma Linda University Health

TODAY

Inside this issue:

-- School of Medicine honors Leonard Bailey’s contributions to infant heart transplant field
-- School of Pharmacy graduates encouraged to find value in life beyond work
-- School of Dentistry graduates begin their professional journeys
-- Allied Health Professions graduates encouraged to share love of Jesus with their future patients
-- School of Public Health graduating class represents 25 nations
-- Schools of Religion, Behavioral Health graduates encouraged to serve others
-- School of Nursing celebrates milestone as 10,000th graduate receives degree
-- University President’s Award winners announced for 2018
-- 42 graduate from San Manuel Gateway …

Commencement Program 2018, Loma Linda University

Commencement Programs

CONTENTS

1 | Message from the President

3 | 2018 Events of Commencement

5 | The Academic Procession

7 | Significance of Academic Regalia

9 | The Good Samaritan

10 | University History Highlights

12 | Loma Linda University Song - "Healing Love"

13 | Criteria for Institutional Awards—Loma Linda University and Loma Linda University Health

15 | Loma Linda University Health and Loma Linda University Honorees

32 | The Programs, The School Honorees, and The Speakers

• School of Medicine, 33
• School of Pharmacy, 63
• School of Dentistry, 76
• School of Allied Health Professions - Allied Health Studies, Cardiopulmonary Sciences, …

The Effect Of A Social Communication Intervention On The Correct Production Of Emotion Words In Children With Language Impairment, Annelise Luddington

Theses and Dissertations

Children diagnosed with Language Impairment (LI) often have difficulty with aspects of social communication. This thesis evaluates the effects of a social communication intervention focused on facilitating the correct production of emotion words in four elementary school-aged children with LI. Researchers monitored changes from pretreatment baseline data, through the intervention, and ended with posttreatment follow-up data for the emotions happiness, surprise, fear, anger, sadness, and disgust. Based on baseline measures, emotion categories in which the child showed limited proficiency were targeted for the 20 intervention sessions. The emotions targeted were different for each child. Each intervention session contained a combination …

Agronomic And Chemical Performance Of Field-Grown Tobacco Engineered For Triterpene And Methylated Triterpene Metabolism, Zuodong Jiang, Chase Kempinski, Santosh Kumar, Scott Kinison, Kristin Linscott, Eric Nybo, Sarah Janze, Constance Wood, Joseph Chappell

Pharmaceutical Sciences Faculty Publications

Squalene is a linear intermediate to nearly all classes of triterpenes and sterols and is itself highly valued for its use in wide range of industrial applications. Another unique linear triterpene is botryococcene and its methylated derivatives generated by the alga Botryococcus braunii race B, which are progenitors to fossil fuel deposits. Production of these linear triterpenes was previously engineered into transgenic tobacco by introducing the key steps of triterpene metabolism into the particular subcellular compartments. In this study, the agronomic characteristics (height, biomass accumulation, leaf area), the photosynthetic capacity (photosynthesis rate, conductance, internal CO₂ levels) and triterpene content …

Modulation Of Primary Amine Oxidase By Phytochemicals, Padraig Shanahan

Masters

Primary Amine Oxidase (PrAO) is an enzyme with a variety of physiological roles. It catalyses the oxidative deamination of primary amines to the corresponding aldehydes. PrAO converts amines such as methylamine and aminoacetone to reactive compounds that can damage small blood vessel proteins. It also acts as a vascular adhesion protein (VAP-1) where it is essential for the migration of leukocytes through the vascular endothelium. Inhibitors of PrAO have been reported to have anti-cancer, anti-diabetic and anti-inflammatory action. In this study we explore the interaction between dietary phytochemicals and Bovine PrAO. Methylxanthines (MXs) are food alkaloids having a positive association …

Risk Factors Associated With Seroprevalence Of Paratuberculosis In Mature Goats In Northeastern Thailand, Sarinya Rerkyusuke, Kwankate Kanistanon, Sarthorn Porntrakulpipat, Aran Janlun

The Thai Journal of Veterinary Medicine

The aim of this study was to investigate risk factors for the seroprevalence of paratuberculosis in mature goats in Northeastern Thailand. The study area included Buriram, Chaiyaphum, Kalasin, Khon Kaen, Mahasarakham, Nakhonratchasrima, Roi et, Sakon Nakhon, Srisaket, and Udonthani. The seroprevalence of paratuberculosis determined in 37 herds, a total of 671 serum samples, was 12.82%. The risk factors related to paratuberculosis were analyzed at individual level using mixed model logistic regression. At the individual level, 86 of 671 goats tested positive based on an ELISA assay. Risk factors associated with the seroprevalence of MAP antibodies included age, divided into six …

Failure To Conceive In Deslorelin-Induced Oestrous Bitches With Regard To Removal Of Hormone Implants After Ovulation, Suppawiwat Ponglowhapan, Atid Suthamnatpong, Achiraya Khamanarong, Ekkapol Akaraphutoporn, Uttra Jamikorn, Suphanut Kulabsri

The Thai Journal of Veterinary Medicine

Removal of a GnRH agonist deslorelin implant either before or during ovulation in deslorelin-induced oestrous bitches is suggested because prolonged administration of the slow-release agonist may compromise luteal function secondary to pituitary down-regulation. This study aimed at investigating the effect of 4.7 mg deslorelin (Suprelorin®) on oestrous induction, ovulation and conception rate after removing the implant 72-96 hours postovulation to ensure that the entire ovulation process was complete. Ovulation began when serum progesterone reached 5-6 ng/mL. The implants were inserted subcutaneously in the umbilical area in 5 healthy, intact anoestrous beagles (1.5-3 years). Time of implantation was considered as Day …

Molecular Characterization Of Common Respiratory Viral Infections In Broilers In Al-Hassa, Eastern Province, Saudi Arabia, Ahmed M. Al-Ali, Ibrahim M. El-Sabagh, Mahmoud H. Mohamed, Ahmed M. Alluwaimi, Ibrahim A. Arif

The Thai Journal of Veterinary Medicine

Newcastle disease virus (NDV), Infectious bronchitis virus (IBV) and H9N2 avian influenza virus (AIV) are the most significant respiratory pathogens. Several outbreaks have been reported frequently in Saudi Arabia despite of the intensive use of vaccination programs. Ten broiler flocks suffering from complicated respiratory disease were subjected to necropsy and samples were collected for molecular identification of involved viruses and pathogenic bacterial infections. Seven out of the ten flocks were positive for single or combined viral infection. The seven flocks were positive for HA test. All positive samples were subjected for molecular identification, three flocks were positive for single NDV …

Feasibility Of Using Screw-Acrylic Bar Technique For Canine Mandibular Fracture Fixation, Pakpoom Sahapibonchai, Monchanok Vijarnsorn, Narudee Kashemsant, Wichit Tharanon

The Thai Journal of Veterinary Medicine

Bone plates and screws (BPS) have been used for mandibular fracture repair for decades. Although bone healing can be achieved, complications such as damage of dental roots and the inferior alveolar nerve in the mandibular canal have been reported. A screw-acrylic bar technique (SAB) was developed in this study as an approach to minimize those complications. The objective of this study was to compare the percentage of dental root and mandibular canal damage induced by inappropriate screw insertion using the SAB technique with that using BPS fixation. Fifteen mesocephalic canine cadavers were used for this study. For each cadaver, bilateral …

Generation Of Epidermal Growth Factor And Green Fluorescent Protein Coexpressing Lactobacillus Acidophilus And Its Effect On Intestinal Histology Improvement In Mature Lps-Challenged Mice, Yang Lv, Ping Kang, Lin Zhang, Xueni Li, Lei Wang, Di Zhao, Dan Yi, Binying Ding, Hongbo Chen, Yongqing Hou, Tao Wu

The Thai Journal of Veterinary Medicine

The aim of the present study was to construct a recombinant strain by using the probiotics Lactobacillus acidophilus expressing the epidermal growth factor (EGF), which can improve intestinal morphology, and to test its effect on the intestinal histology in LPS (lipopolysaccharide)-challenged mice. The EGF gene was cloned into the shuttle vector pSET4s and then transformed into the L. acidophilus MG6243 strain by electroporation. Two recombinant strains were confirmed by SDS-PAGE and named ΔMG6243-1 and ΔMG6243-2. Sixty mice were randomly assigned to six treatments: 1) non-challenged control, 2) LPS-challenged control, 3) LPS-challenged + 200 μl MG6243, 4) LPSchallenged + 200 μl …

Single Nucleotide Polymorphism (Snp) Of Leptin Gene In Holstein Cattle, Mohammed Baqur S. Al-Shuhaib, Sara M. A. Al-Lamy, Hafedh M. A. Al-Tayy, Tahreer M. Al-Thuwaini, Adil H. Radhi

The Thai Journal of Veterinary Medicine

Leptin is a versatile important hormone that regulates several metabolic pathways, such as controlling body weight, feed intake, energy expenditure, immune function, and reproduction. This study was conducted to describe the single nucleotide polymorphisms (SNPs) within bovine leptin (LEP) gene, and their possible consequences on leptin structure and function in Holstein cattle. After collecting blood samples from 60 Holstein cattle, extracting their genomic DNA, two PCR-specific primers were designed. Both PCR and SSCP experiments were optimized and performed for each PCR fragment. Each different set of SSCP resolved bands was sequenced and analyzed. Two SSCP patterns representing two genotypes (AA, …

Anti-Helicobacter Pylori Activity And Inhibition Of Gastritis By Magnolia Officinalis Extract, Hyun-A Lee, Sunhwa Hong, Ji-Hyun Yoo, Okjin Kim

The Thai Journal of Veterinary Medicine

The potential inhibitory effect of Magnolia officinalis extract (MOE) on Helicobacter pylori was studied by using (i) disk agar diffusion assay, (ii) in vitro inhibition assays of H. pylori adhesion to human gastric adenocarcinoma epithelial cell line AGS cells, (iii) inhibition of H. pylori-induced inflammation in AGS cell, and (iv) in vivo H. pylori SS1 mouse model of infection over a period of 4 weeks. Results indicated that MOE had a wide range of inhibitory effect against H. pylori growth. The inhibition of H. pylori adherence to gastric epithelial cells was identified by MOE. In addition, MOE inhibited H. pylori-induced …

Erk Mapk Signaling Pathway Regulates Porcine Circovirus Type 2 Replication In Peripheral Blood Mononuclear Cells, Win Surachetpong, Sunaree Nantakhruea, Phiangfhun Inthasaeng, Porntippa Lekcharoensuk

The Thai Journal of Veterinary Medicine

Porcine circovirus type 2 (PCV2) is one of the most important swine viral diseases in Thailand and worldwide. While the interaction between PCV2 and pig immune system has been largely explored, the mechanisms by which PCV2 replicates in porcine immune cells and alters host cellular signaling pathways remain incomplete. In this study, extracellular regulated kinase (ERK) phosphorylation form was shown to slightly increase in PCV2-infected peripheral blood mononuclear cells (PBMCs) at 48 hr post infection. To demonstrate the role of ERK MAPK signaling, PBMCs were divided into three groups including control, virus, and virus with the mitogen-activated protein kinase (MEK) …

Efficacy Of Postoperative Oral Tepoxalin After Decompressive Surgery In Dogs With Degenerative Lumbosacral Stenosis, Niyada Thitaram, Herman A.W. Hazewinkel, Björn P. Meij

The Thai Journal of Veterinary Medicine

Twenty-three client-owned dogs with degenerative lumbosacral stenosis (DLS) treated by decompressive surgery were included in this study. The dogs were assigned to postoperative medication protocols of tepoxalin (10 mg/kg, SID) for 2 weeks (8 dogs, group 1), of tepoxalin (10 mg/kg, SID) for 6 weeks (7 dogs, group 2), and of carprofen (2 mg/kg, BID) for 2 weeks (8 dogs, group 3). Gait function after decompressive surgery of the dogs was evaluated by force plate analysis (FPA) and questionnaires filled out by their owners. FPA was performed before surgery, and at 4 days, 6 weeks, and 6 months after surgery. …

Fatigue Study Of Cancellous And Cortical Stainless Steel Screws Used With Polymethymethacrylate And The Sop Plate System For Immobilisation Of Vertebral Luxation In Canine Cadavers, Mingrath Mekavichai, Nattanon Kanjanawong, Tanachort Chattammanat, Kumpanart Soontornvipart

The Thai Journal of Veterinary Medicine

Globally, vertebral fracture and luxation (VFL) are one of the most common neurological injuries in dogs and cats. The standard care for vertebral body stabilisation of canine VFL is the use of screws with polymethylmethacrylate (PMMA) and the string of pearls (SOP) plate system fixation. VFL with implants are usually exposed to force in a repetitive or cyclic loading fashion. Indeed, stress on the implant cyclically at a load significantly less than its ultimate tensile strength can cause fatigue failure, one of the major causes of implant breakage. This study aims to compare the fatigue property and failure mode of …

Detection Of Transforming Growth Factor Beta 1 In Normal Dogs And Dogs With Degenerative Mitral Valve Disease, Wiyada Winyuchonharoen, Somporn Techangamsuwan, Sirilak Disatian Surachetpong

The Thai Journal of Veterinary Medicine

Degenerative mitral valve disease (DMVD) is a common finding of acquired heart diseases in small and medium-sized adult dogs. Transforming growth factor beta 1 (TGF-β1) was found to increase in valves of DMVD dogs. However, plasma TGF-β1 concentrations in dogs with DMVD have not been evaluated before. The objective of the present study was to compare the plasma concentration of TGF-β1 between normal dogs and dogs with DMVD by using an ELISA technique. This measurement might help to distinguish dogs with DMVD from healthy dogs. The Mann-Whitney U test was used to compare plasma TGF-β1 concentrations between the two groups. …