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2018

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Articles 14431 - 14460 of 15422

Full-Text Articles in Medicine and Health Sciences

Correlating Residual Stress With Personal And Professional Characteristics In Aircraft Pilots, Erik Eckblad Jan 2018

Correlating Residual Stress With Personal And Professional Characteristics In Aircraft Pilots, Erik Eckblad

Walden Dissertations and Doctoral Studies

Every day aircraft pilots must successfully resolve significant inflight situations and then manage the possibility of residual psychological and physiological stress. Previous research has shown primary attention is given to presignificant event training and stress management, however there remains an important gap in the current literature regarding postsignificant event stress within the aviation profession. The purpose of this cross-sectional quantitative study was to use the observational lens of stress theory and survey U.S. pilots who have experienced an inflight emergency, looking for correlation between factors such as age, gender, flight experience, and training against a pilot's self-reported level of residual …


A Meta-Analysis Of Video Based Interventions In Adult Mental Health, Lauretta Kaye Montes Jan 2018

A Meta-Analysis Of Video Based Interventions In Adult Mental Health, Lauretta Kaye Montes

Walden Dissertations and Doctoral Studies

Symptoms of mental illness such as anxiety and depression diminish functioning, cause distress, and create an economic burden to individuals and society. This meta-analysis was designed to evaluate the effectiveness of video based interventions (VBIs) for the treatment of adults in mental health settings. VBIs comprise four different ways of using video in mental health therapy, including video modeling, video exposure, video feedback, and videos used for psychoeducation. Bandura's social learning theory, Beck's cognitive theory, and Dowrick's theory of feedforward learning form the theoretical framework for understanding how VBIs work. The research questions were: (a) what is the range of …


Locus Of Control, Poverty And Health Promoting Lifestyles, Cara Stephenson-Hunter Jan 2018

Locus Of Control, Poverty And Health Promoting Lifestyles, Cara Stephenson-Hunter

Walden Dissertations and Doctoral Studies

Despite increased access to care and interventions aimed to change health behavior, socioeconomic health disparities have remained unchanged, even for preventable illness and disease. Health behavior theories and interventions heavily rely on perceptions of control over one's fate and thus ignore populations with low perceptions of personal control. Poverty is associated with an external locus of control (LOC), while both poverty and external LOC are associated with less health protective behavior. The purpose of this quantitative study was to explore the role of LOC as an adaptive response to poverty and to discover the risks and benefits to physical and …


Knowledge, Perceived Barriers, And Preventive Behaviors Associated With Cardiovascular Disease Among Gallaudet University Employees, Andy Kenji Tao Jan 2018

Knowledge, Perceived Barriers, And Preventive Behaviors Associated With Cardiovascular Disease Among Gallaudet University Employees, Andy Kenji Tao

Walden Dissertations and Doctoral Studies

When the Minority Health Improvement and Health Disparity Elimination Act of 2007 went into effect, there was a corresponding increase in research focused on cardiovascular disease (CVD) in underrepresented groups, except for 1: culturally Deaf Americans. Guided by the health belief model, the purpose of this study was to determine if there were significant differences in the level of knowledge, perceived barriers, and preventive behaviors associated with CVD among Deaf and hearing employees at Gallaudet University, Washington D.C. This cross-sectional quantitative research study used a survey with questions derived from 2 existing national surveys. One hundred eighty-six subjects were recruited …


Simulation-Based Education To Decrease Cauti Rates In The Intensive Care, Janet Belanger Bell Jan 2018

Simulation-Based Education To Decrease Cauti Rates In The Intensive Care, Janet Belanger Bell

Walden Dissertations and Doctoral Studies

Catheter-associated urinary tract infections (CAUTIs) occur frequently in Intensive Care Unit (ICU) patients, who are hospitals' most vulnerable population. This quality improvement project is the evaluation of 2 interventions used in one acute care facility's ICU to decrease CAUTI rates over a 3-year timeline. The 2 interventions used for the project were 1) an evidence-based guideline developed from the Comprehensive Unit-based Safety Program and 2) simulation-based education for teaching the guideline. Using the Iowa model and Havelock's theory of planned change as a framework, the 2 interventions were evaluated over a 3-year timeline: 2014 pre- intervention, 2015 intervention, and 2016 …


Implications Of An All Bsn Workforce Policy, Mary Clifford Jan 2018

Implications Of An All Bsn Workforce Policy, Mary Clifford

Walden Dissertations and Doctoral Studies

Discussion continues about requiring a Bachelor of Science in Nursing (BSN) as the minimum requirement for entry into registered nursing practice. A Magnet-® recognized hospital located in the Northeast United States is requiring all registered nurses without a BSN (n=284 or 28%) to obtain their BSN by 2022 as a condition for employment. The purpose of this project was to quantify the potential number and rationale of nurses who are not planning to return to school. The 2 practice focused questions are (a) What is the rationale for nurses who do not plan to pursue their BSN degree and (b) …


Evaluating The Impact Of An Early Warning Scoring System In A Community Hospital Setting, Christine Conner Jan 2018

Evaluating The Impact Of An Early Warning Scoring System In A Community Hospital Setting, Christine Conner

Walden Dissertations and Doctoral Studies

Failure to recognize and respond to early signs of deterioration in hospitalized patients can have significant implications associated with delays in treatment. This lack of recognition was the impetus for rapid response teams in the United States and the recommendation by the Institute of Healthcare Improvement for use of early warning scores. This project was designed to evaluate the pilot implementation of an early warning score on 2 units in a community hospital in the Northeast. The practice-focused question was used to explore how patient outcomes changed following implementation of an early warning score (EWS) compared to patient outcomes associated …


Successful Project Management, Tomomi M. Horning Jan 2018

Successful Project Management, Tomomi M. Horning

Walden Dissertations and Doctoral Studies

High project failure rates result in billions of wasted dollars each year. Project failure does not discriminate by type of project or the industry from which they originate. The purpose of this qualitative single case study was to explore strategies that leaders at a health care organization located in Pennsylvania use to manage projects successfully. This population was selected due to the health care organization's reputation for successful project completion. The conceptual framework for this study was Fiedler's contingency theory. Data were collected by conducting semistructured interviews with 9 project leaders and reviewing project documents provided by study participants. Interviews …


Stroke Risk Factor Knowledge, Attitude, Prevention Practices, And Stroke, Adaku Ngozika Madubuko Jan 2018

Stroke Risk Factor Knowledge, Attitude, Prevention Practices, And Stroke, Adaku Ngozika Madubuko

Walden Dissertations and Doctoral Studies

Regardless of the advances that have been made in stroke research and treatment and the overall decrease in stroke mortality, the stroke mortality rate for African Americans is still high at 45.2/100,000 and is still the leading cause of adult disability. Knowledge of the risk factors of stroke is paramount to reducing the morbidity and mortality of stroke, but knowledge of stroke risk factors has been found to be suboptimal in the African American population. The purpose of this study was to examine if there is a relationship between the knowledge, perception, and sources of stroke information of risk factors …


Job Satisfaction And The Effects And Influences On Nurse Retention, Burke N. Kline Jan 2018

Job Satisfaction And The Effects And Influences On Nurse Retention, Burke N. Kline

Walden Dissertations and Doctoral Studies

Researchers have predicted that by 2020 the United States will experience a severe shortage of registered nurses. The purpose of this correlation study, using the National Sample Survey of Registered Nurses 2008, was to investigate the relationship between nurse job satisfaction and its effect on nurse retention nationwide. Secondary data sets from the 2008 National Sample Survey of Registered Nurses and examining relationships between the variable of nurse retention and job satisfaction. Bivariate (correlation coefficient, chi squares, and simple linear regression) and multivariate (logistic regression) analyses identified and connected associations and examined measurement levels between the dependent and independent variables, …


A Qualitative Exploration Of Transformative Learning Within An Online Leadership Course, Melissa M. Sweetman Jan 2018

A Qualitative Exploration Of Transformative Learning Within An Online Leadership Course, Melissa M. Sweetman

Journal of Occupational Therapy Education

As the profession of occupational therapy enters its second century of existence, it is important to recognize that for continued sustainability and strength through the effects of healthcare reform, strong leadership is required. While experts agree that leadership development for occupational therapists needs to begin in the classroom setting, there is little existing research on occupational therapy leadership education. Built upon a theoretical framework of the transformative learning theory, this qualitative study sought to determine whether students in an online leadership course within a post-professional doctor of occupational therapy degree program believed they experienced a transformation in their leadership knowledge …


The Development Of A Role-Emerging Fieldwork Placement In A Homeless Shelter, Quinn Tyminski Jan 2018

The Development Of A Role-Emerging Fieldwork Placement In A Homeless Shelter, Quinn Tyminski

Journal of Occupational Therapy Education

The purpose of this project was to develop and evaluate student learning outcomes of a role-emerging fieldwork Level II placement in a local homeless shelter. A role-emerging fieldwork placement denotes any placement in which there is not an identified occupational therapy program or no on-site occupational therapy (OT) supervisor. The project ran from January through June 2017 at a local homeless shelter with 1 Masters of Occupational Therapy (MOT) student from a local university completing their first Level II fieldwork rotation from January through March, followed by 2 MOT students completing their second rotation from April through June. Fieldwork supervision …


The Impact Of An Interprofessional Geriatric Training Experience: Attitudes Of Future Healthcare Providers, Lisa J. Knecht-Sabres, Minetta Wallingford, Michelle M. Lee, James F. Gunn, Esperanza M. Anaya, Sarah E. Getch, Nathaniel D. Krumdick, Gloria M. Workman Jan 2018

The Impact Of An Interprofessional Geriatric Training Experience: Attitudes Of Future Healthcare Providers, Lisa J. Knecht-Sabres, Minetta Wallingford, Michelle M. Lee, James F. Gunn, Esperanza M. Anaya, Sarah E. Getch, Nathaniel D. Krumdick, Gloria M. Workman

Journal of Occupational Therapy Education

As the older adult population increases, it is vital to educate and train healthcare providers as members of interprofessional healthcare teams who can work effectively with these individuals. Ageism is a potential obstacle to achieving this goal. The purpose of this pre/post-test design pilot study was to determine the impact of an interprofessional geriatric training experience on the attitudes of future healthcare providers towards interprofessionalism and working with older adults. Sixteen graduate level students from occupational therapy and clinical psychology programs completed four interprofessional sessions with older adults residing in a long-term care facility. Quantitative data were gathered from pre/post-test …


Occupational Therapy Practice Patterns In Two Rural States: Does The College Experience Influence Rural Employment Choice?, Debra J. Hanson, Janet S. Jedlicka, Nicole C. Harris, Marilyn G. Klug Jan 2018

Occupational Therapy Practice Patterns In Two Rural States: Does The College Experience Influence Rural Employment Choice?, Debra J. Hanson, Janet S. Jedlicka, Nicole C. Harris, Marilyn G. Klug

Journal of Occupational Therapy Education

An online survey was conducted of 225 occupational therapy (OT) practitioners living in the rural states of North Dakota and Wyoming to explore practice patterns and the influence of the college experience on employment choice. Findings showed that rural practitioners had greater variability of hours spent working (5.5 more hours per week, p=.028), and one more work location on average (p=.006). Therapists in urban settings spent 15% more time in fieldwork education than their rural counterparts (p=.021). Rural practice choice was influenced by participation in Level I and Level II fieldwork (p=.002) but not by loan debt. Study implications for …


Enhancing Professionalism Among Ot Students: The Culture Of Professionalism, Kate Reiter, Loriann Helgeson, Supawadee C. Lee Jan 2018

Enhancing Professionalism Among Ot Students: The Culture Of Professionalism, Kate Reiter, Loriann Helgeson, Supawadee C. Lee

Journal of Occupational Therapy Education

Occupational therapy (OT) students are likely to experience generational differences when interacting with faculty and clients. Each generational group has a shared culture and unique set of experiences that influence their behavior, expectations, and perceptions surrounding professionalism. When teaching professionalism to OT students, the cultural underpinnings and influences related to generational groups and their differences become important considerations. This manuscript explores the relationship between culture and professionalism and describes how generational culture influences professional behaviors. It presents a reflective process and guide developed by the authors to enhance professionalism and cultural effectiveness among OT students and guide them in meeting …


An Online Training To Prepare Occupational Therapy Students To Work With Clients With Limited English Proficiency And Interpreters, Elizabeth A. Harrison, Mansha Mirza Jan 2018

An Online Training To Prepare Occupational Therapy Students To Work With Clients With Limited English Proficiency And Interpreters, Elizabeth A. Harrison, Mansha Mirza

Journal of Occupational Therapy Education

Effective communication between occupational therapists (OTs) and their clients is key to quality, client-centered services. Most OTs can expect to work with clients with Limited English Proficiency (LEP). Language barriers may negatively impact client safety and client satisfaction. Working with language interpreters is a key means for OTs to best serve clients with LEP; however, few OT curricula provide adequate training in working with interpreters. This paper presents a new, innovative online training for preparing OT students to work with clients with LEP and interpreters. The brief online training used informational slides, video role plays and written case studies to …


Relationship Between Strength And Power Production Capacities In Trained Sprint Track Cyclists, James Vercoe, Mike R. Mcguigan Jan 2018

Relationship Between Strength And Power Production Capacities In Trained Sprint Track Cyclists, James Vercoe, Mike R. Mcguigan

Research outputs 2014 to 2021

The purpose of this study was to investigate the relationship between strength and power capabilities in trained sprint track cyclists. Ten participants including six women and four men (age: 22.1±6.8 years, body height: 176.1±6.7 cm, body weight: 72.1±7.9 kg) performed isometric mid-thigh pull (IMTP) and isokinetic sprint tests. Variables measured included peak force (PF), peak rate of force development (PRFD) for the IMTP and maximal torque and maximal power (Pmax) for the isokinetic sprint test. There was a strong relationship between PF on the IMTP and maximal peak torque values across five isokinetic sprints (r=.890-.925). Strong relationships were also shown …


Vegetable Diversity, Injurious Falls, And Fracture Risk In Older Women: A Prospective Cohort Study, Marc Sim, Lauren C. Blekkenhorst, Joshua Lewis, Catherine P. Bondonno, Amanda Devine, Kun Zhu, Richard J. Woodman, Richard L. Price, Jonathan M. Hodgson Jan 2018

Vegetable Diversity, Injurious Falls, And Fracture Risk In Older Women: A Prospective Cohort Study, Marc Sim, Lauren C. Blekkenhorst, Joshua Lewis, Catherine P. Bondonno, Amanda Devine, Kun Zhu, Richard J. Woodman, Richard L. Price, Jonathan M. Hodgson

Research outputs 2014 to 2021

The importance of vegetable diversity for the risk of falling and fractures is unclear. Our objective was to examine the relationship between vegetable diversity with injurious falling and fractures leading to hospitalization in a prospective cohort of older Australian women (n = 1429, ≥70 years). Vegetable diversity was quantified by assessing the number of different vegetables consumed daily. Vegetable intake (75 g servings/day) was estimated using a validated food frequency questionnaire at baseline (1998). Over 14.5 years, injurious falls (events = 568, 39.7%), and fractures (events = 404, 28.3%) were captured using linked health records. In multivariable-adjusted Cox regression models, …


Independent And Interactive Associations Of Negative Affect, Restraint, And Impulsivity In Relation To Binge Eating Among Women, Tyler B. Mason, Kathryn E. Smith, Jason M. Lavender, Robin J. Lewis Jan 2018

Independent And Interactive Associations Of Negative Affect, Restraint, And Impulsivity In Relation To Binge Eating Among Women, Tyler B. Mason, Kathryn E. Smith, Jason M. Lavender, Robin J. Lewis

Psychology Faculty Publications

There is growing recognition that impulsivity may serve as an underlying risk factor for binge eating. In addition, the association of impulsivity with binge eating may be moderated by other affective and cognitive risk factors. This study examined independent and interactive associations of negative affect, dietary restraint, and facets of impulsivity with binge eating. A diverse sample of 566 undergraduate women completed online questionnaires of study variables. Results revealed a three-way interaction of negative affect, dietary restraint, and attentional impulsivity in relation to binge eating. Women who were high on each of these three variables reported the greatest levels of …


Preconceptional Health Behavior Change In Women With Overweight And Obesity: Prototype For Smart Strong Healthy Women Intervention, Frank T. Materia, Joshua M. Smyth, Kristin E. Heron, Marianne Hillemeier, Mark E. Feinberg, Patricia Fonzi, Danielle Symons Jan 2018

Preconceptional Health Behavior Change In Women With Overweight And Obesity: Prototype For Smart Strong Healthy Women Intervention, Frank T. Materia, Joshua M. Smyth, Kristin E. Heron, Marianne Hillemeier, Mark E. Feinberg, Patricia Fonzi, Danielle Symons

Psychology Faculty Publications

Background: The prevalence of maternal perinatal obesity is rising, and in turn, increases health risks and morbidity for both mother and child. Past evidence suggests the preconceptional Strong Healthy Women (SHW) intervention can reduce multiple biobehavioral risk factors for adverse perinatal health. The SHW intervention, however, was time- and resource-intensive to deliver. Mobile health (mHealth) technologies provide an opportunity to expand intervention reach while reducing implementation cost and burden. Previous research suggests that preconceptional women are broadly supportive of using smartphones for behavior change, yet few studies have elicited their specific preferences for a targeted mHealth intervention. The objective of …


Sexual Coercion, Drinking To Cope Motives, And Alcohol-Related Consequences Among Self-Identified Bisexual Women, Michelle L. Kelly, Sarah J. Ehlke, Robin J. Lewis, Abby L. Braitman, Wendy Bostwick, Kristin E. Heron, Cathy Lau-Barraco Jan 2018

Sexual Coercion, Drinking To Cope Motives, And Alcohol-Related Consequences Among Self-Identified Bisexual Women, Michelle L. Kelly, Sarah J. Ehlke, Robin J. Lewis, Abby L. Braitman, Wendy Bostwick, Kristin E. Heron, Cathy Lau-Barraco

Psychology Faculty Publications

Background: Given higher sexual victimization and greater alcohol use among bisexual women, a critical public health challenge is to understand within-group variation that may heighten or explain these associations in bisexual women. Objectives: The present study tested a moderated-mediation model in which sexual coercion was hypothesized to be associated with alcohol-related consequences via drinking to cope motives in self-identified bisexual women who reported at least occasional binge drinking. Negative affect was hypothesized to moderate the sexual coercion-drinking to cope motives association. Methods: Participants were a community sample of 107 self-identified bisexual women (age M = 20.97, SD = 2.11) who …


Measuring Sexual Minority Stressors In Lesbians Women's Daily Lives: Initial Scale Development, Kristin Heron, Abby L. Braitman, Robin J. Lewis, Alexander T. Shappie, Phoebe T. Hitson Jan 2018

Measuring Sexual Minority Stressors In Lesbians Women's Daily Lives: Initial Scale Development, Kristin Heron, Abby L. Braitman, Robin J. Lewis, Alexander T. Shappie, Phoebe T. Hitson

Psychology Faculty Publications

Lesbian women face unique sexual minority stressors (SMS) because of their stigmatized and marginalized status in society. Existing studies of SMS are primarily cross-sectional and use global measures of SMS. The goal of the present study was to develop a brief daily measure of SMS for use in daily diary or ecological momentary assessment studies. Existing retrospective measures of SMS were reviewed, resulting in an initial pool of 29 items. Thirty-eight lesbian women (Mage = 24.3 years, range: 19–30 years) completed a daily web-based survey including the SMS items for 12 days. Two response scales were tested; participants were randomized …


Cultural Stressors, Identity Development, And Substance Use Attitudes Among Hispanic Immigrant Adolescents, Timothy J. Grigsby, Myriam Forster, Alan Meca, Byron L. Zamboanga, Seth J. Schwartz, Jennifer B. Unger Jan 2018

Cultural Stressors, Identity Development, And Substance Use Attitudes Among Hispanic Immigrant Adolescents, Timothy J. Grigsby, Myriam Forster, Alan Meca, Byron L. Zamboanga, Seth J. Schwartz, Jennifer B. Unger

Psychology Faculty Publications

The goal of this investigation was to determine whether various cultural stressors (bicultural stress, perceived discrimination, and perceived negative context of reception [PNCR]) predict positive and negative substance use attitudes, directly and indirectly through personal identity, in a sample of immigrant Hispanic adolescents. Data on cultural stressors, substance use attitudes, and covariates were collected from 302 Hispanic immigrant adolescents (152 from Miami [61% Cuban] and 150 from Los Angeles [70% Mexican]) at 3 time points. PNCR was associated with identity confusion (𝛽=.175, p=.033). Identity confusion significantly predicted higher positive attitudes toward alcohol and other drug (AOD; 𝛽 =.216, p<.001) and cigarette use (𝛽=.191, p=.015) and mediated the relationship between PNCR with unfavorable AOD attitudes (𝛽 =-.019, 95% confidence interval [CI] [-0.052,-0.001]) and favorable AOD attitudes (𝛽=0.038, 95% CI [0.003, 0.086]). Perceptions of a negative context of reception may hinder successful personal identity formation and impact health outcomes for immigrant youth.


Mechanotransduction Signaling In Podocytes From Fluid Flow Shear Stress., Tarak Srivastava, Hongying Dai, Daniel P. Heruth, Uri S. Alon, Robert E. Garola, Jianping Zhou, R Scott Duncan, Ashraf El-Meanawy, Ellen T. Mccarthy, Ram Sharma, Mark L. Johnson, Virginia J. Savin, Mukut Sharma Jan 2018

Mechanotransduction Signaling In Podocytes From Fluid Flow Shear Stress., Tarak Srivastava, Hongying Dai, Daniel P. Heruth, Uri S. Alon, Robert E. Garola, Jianping Zhou, R Scott Duncan, Ashraf El-Meanawy, Ellen T. Mccarthy, Ram Sharma, Mark L. Johnson, Virginia J. Savin, Mukut Sharma

Manuscripts, Articles, Book Chapters and Other Papers

Recently, we and others have found that hyperfiltration-associated increase in biomechanical forces, namely, tensile stress and fluid flow shear stress (FFSS), can directly and distinctly alter podocyte structure and function. The ultrafiltrate flow over the major processes and cell body generates FFSS to podocytes. Our previous work suggests that the cyclooxygenase-2 (COX-2)-PGE2-PGE2 receptor 2 (EP2) axis plays an important role in mechanoperception of FFSS in podocytes. To address mechanotransduction of the perceived stimulus through EP2, cultured podocytes were exposed to FFSS (2 dyn/cm2) for 2 h. Total RNA from cells at the end of FFSS treatment, 2-h post-FFSS, and 24-h …


Clinical Application Of Circulating Tumor Cells And Circulating Tumor Dna In Uveal Melanoma, Aaron Beasley, Timothy Isaacs, Muhammad K. Khattak, James B. Freeman, Richard Allcock, Fred K. Chen, Michelle R. Pereira, Kyle Yau, Jaqueline Bentel, Tersia Vermeulen, Leslie Calapre, Michael Millward, Melanie R. Ziman, Elin S. Gray Jan 2018

Clinical Application Of Circulating Tumor Cells And Circulating Tumor Dna In Uveal Melanoma, Aaron Beasley, Timothy Isaacs, Muhammad K. Khattak, James B. Freeman, Richard Allcock, Fred K. Chen, Michelle R. Pereira, Kyle Yau, Jaqueline Bentel, Tersia Vermeulen, Leslie Calapre, Michael Millward, Melanie R. Ziman, Elin S. Gray

Research outputs 2014 to 2021

Purpose To evaluate the feasibility of using circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) for the management of uveal melanoma (UM).

Patients and Methods Low-coverage whole-genome sequencing was used to determine somatic chromosomal copy number alterations (SCNAs) in primary UM tumors, ctDNA, and whole-genome amplified CTCs. CTCs were immunocaptured using an antimelanoma-associated chondroitin sulfate antibody conjugated to magnetic beads and immunostained for melanoma antigen recognised by T cells 1 (MART1)/glycoprotein 100 (gp100)/S100 calcium-binding protein β (S100β). ctDNA was quantified using droplet digital polymerase chain reaction assay for mutations in the GNAQ, GNA11, PLCβ4, and CYSLTR2 …


White Matter Hyperintensities And The Mediating Role Of Cerebral Amyloid Angiopathy In Dominantly-Inherited Alzheimer’S Disease, Seonjoo Lee, Molly E. Zimmerman, Atul Narkhede, Sara E. Nasrabady, Giuseppe Tosto, Irene B. Meier, Tammie L.S. Benzinger, Daniel S. Marcus, Anne M. Fagan, Nick C. Fox, Nigel J. Cairns, David M. Holtzman, Virginia Buckles, Bernardino Ghetti, Eric Mcdade, Ralph Martins, Andrew J. Saykin, Colin L. Masters, John M. Ringman, Stefan Fӧrster, Peter R. Schofield, Reisa A. Sperling, Keith A. Johnson, Jasmeer P. Chhatwal, Stephen Salloway, Stephen Correia, Clifford R. Jack, Jr, Michael Weiner, Randall J. Bateman, John C. Morris, Richard Mayeux, Adam M. Brickman Jan 2018

White Matter Hyperintensities And The Mediating Role Of Cerebral Amyloid Angiopathy In Dominantly-Inherited Alzheimer’S Disease, Seonjoo Lee, Molly E. Zimmerman, Atul Narkhede, Sara E. Nasrabady, Giuseppe Tosto, Irene B. Meier, Tammie L.S. Benzinger, Daniel S. Marcus, Anne M. Fagan, Nick C. Fox, Nigel J. Cairns, David M. Holtzman, Virginia Buckles, Bernardino Ghetti, Eric Mcdade, Ralph Martins, Andrew J. Saykin, Colin L. Masters, John M. Ringman, Stefan Fӧrster, Peter R. Schofield, Reisa A. Sperling, Keith A. Johnson, Jasmeer P. Chhatwal, Stephen Salloway, Stephen Correia, Clifford R. Jack, Jr, Michael Weiner, Randall J. Bateman, John C. Morris, Richard Mayeux, Adam M. Brickman

Research outputs 2014 to 2021

Introduction: White matter hyperintensity (WMH) volume on MRI is increased among presymptomatic individuals with autosomal dominant mutations for Alzheimer’s disease (AD). One potential explanation is that WMH, conventionally considered a marker of cerebrovascular disease, are a reflection of cerebral amyloid angiopathy (CAA) and that increased WMH in this population is a manifestation of this vascular form of primary AD pathology. We examined whether the presence of cerebral microbleeds, a marker of CAA, mediates the relationship between WMH and estimated symptom onset in individuals with and without autosomal dominant mutations for AD.

Participants and methods: Participants (n = 175, …


The Effects Of Using Expressive Intervention In Group Counseling On Acculturative Stress And Depressive Symptoms Among Korean Immigrant Women In South And Central Texas :A N Experimental Study, Sun-Kyung Chung Jan 2018

The Effects Of Using Expressive Intervention In Group Counseling On Acculturative Stress And Depressive Symptoms Among Korean Immigrant Women In South And Central Texas :A N Experimental Study, Sun-Kyung Chung

Dissertations

This study evaluated the relationship between acculturative stress and depressive symptoms in Korean immigrant women and evaluated the use of expressive group counseling interventions for these women's acculturative stress and depressive symptoms. Participants were randomly assigned to the intervention or control group. The intervention group received a total of four sessions of expressive group counseling interventions while the control group was asked to color pictures at home. Pearson correlations found statically significant relationships between acculturative stress and depressive symptoms in Korean immigrant women. The results of a one-way analysis of covariance (ANCOVA) indicated no statistically significant difference in the effect …


Low-Level Cadmium Exposure And Cardiovascular Outcomes In Elderly Australian Women: A Cohort Study, Kane Deering, Anna C. Callan, Richard Prince, Wai Lim, Peter Thompson, Joshua Lewis, Andrea Hinwood, Amanda Devine Jan 2018

Low-Level Cadmium Exposure And Cardiovascular Outcomes In Elderly Australian Women: A Cohort Study, Kane Deering, Anna C. Callan, Richard Prince, Wai Lim, Peter Thompson, Joshua Lewis, Andrea Hinwood, Amanda Devine

Research outputs 2014 to 2021

Background

Cadmium has been associated with increased risk of cardiovascular disease (CVD) in observational studies, however there has been a limited focus on this relationship in women.

Objectives

This study investigated the association of urinary cadmium (UCd) concentrations with CVD outcomes and all-cause mortality in elderly Western Australian (WA) women.

Methods

UCd excretion was measured at baseline in 1359 women, mean age 75.2 ± 2.7 years and 14.5 years of atherosclerotic vascular disease (ASVD) hospitalisations and deaths, including both the principle cause of death and all associated causes of death. Health outcome data were retrieved from the Western Australian Data …


Sedentary Time And The Cumulative Risk Of Preserved And Reduced Ejection Fraction Heart Failure: From The Multi-Ethnic Study Of Atherosclerosis, Brandi Scot Rariden Jan 2018

Sedentary Time And The Cumulative Risk Of Preserved And Reduced Ejection Fraction Heart Failure: From The Multi-Ethnic Study Of Atherosclerosis, Brandi Scot Rariden

UNF Graduate Theses and Dissertations

ABSTRACT

Purpose: The purpose of this study was to examine the relationship between self-reported sedentary time (ST) and the cumulative risk of preserved ejection fraction heart failure (HFpEF) and reduced ejection fraction heart failure (HFrEF) using a diverse cohort of U.S. adults 45-84 years of age.

Methods: Using data from the Multi-Ethnic Study of Atherosclerosis (MESA), we identified 6,814 subjects (52.9% female). All were free of baseline cardiovascular disease. Cox regression was used to calculate the hazard ratios (HR) associated with baseline ST and risk of overall heart failure (HF), HFpEF, and HFrEF. Weekly self-reported ST was dichotomized …


Indoor Air Quality In Schools, Clint Pinion Jr. Jan 2018

Indoor Air Quality In Schools, Clint Pinion Jr.

EKU Faculty and Staff Scholarship

An indoor air quality study was conducted on a ‘net-zero energy’ school using a TSI Velocicalc Model 9555-p with probe model 982, passive radon monitors, visual inspection protocol, and an indoor environmental quality survey of school faculty and staff. Average indoor temperature, relative humidity, and carbon dioxide levels in several areas within the school were not within IAQ guidelines. Three rooms on the school’s grounds had radon levels exceeding the action level. Recommended solutions included installing return and supply air ducts in hallways and relative humidity and temperature monitors in classrooms with high-pitched ceilings.