Medicine and Health Sciences Commons^™

Glaucoma Referral Refinement In Ireland: Managing The Sensitivity-Specificity Paradox In Optometric Practice, Catriona Barrett, O'Brien Colm, James Loughman

Articles

Purpose: Glaucoma referral refinement (GRR) has pr ven a successful demand management strategy for glaucoma suspect cases in the United Kingdom (UK). A GRR clinic was established in Dublin, Ireland to investigate the clinical viability of this pathway outside the UK's National Health Service (NHS) structures, and away from the influence of National Institute for Clinical Excellence (NICE) guidance.

Association Of Opioid Metabolism With Aberrant Drug-Related Behaviors Among Non-Malignant Chronic Pain Patients, Eduardo Aguila

Open Access Theses & Dissertations

An estimated 100 million Americans suffer from some form of chronic pain. Chronic opioid therapy (COT) use in non-malignant chronic pain patients (NMCPP) has markedly increased over the past two decades due to growing consensus that COT is suitable for the treatment of moderate-to-severe non-malignant chronic pain. Yet, COT for NMCPP has been widely associated with multiple aberrant drug-related behaviors (ADRB) such as misuse, abuse, diversion, addiction, and pseudoaddiction. One reason for the relative high incidence of ADRB among NMCPP on COT may be genetics-induced medication response variability, which, can result in pharmacotherapy failure and/or toxicity

The present study evaluated …

The Process Of Adoption Of Disruptive Innovations In Local Health Care Agencies Delivering Primary Care, Aurora Aguirre Polanco

Open Access Theses & Dissertations

The current state of the U.S. health care system is complex and limit access to care to many consumers, thus compromising their health outcomes. The problems of limited access and questionable quality can be addressed by focusing on enhancing the primary health care field. Improvements in both the access and performance of primary health care agencies, derive in better health outcomes and cost savings to the system in the long-term. Disruptive innovations, that make products and services simpler and more affordable, are adopted in agencies and potentially improve access and performance measures. However, the adoption of disruptive innovations in local …

Geographic And Multilevel Influences Of School Environments On The Development Of Obesity And Physical Activity Among School Children In A U.S.-Mexico Border Community, Teresa M. Anchondo

Open Access Theses & Dissertations

Childhood obesity, especially in Hispanic populations, is the most serious public health challenge of the 21st century (World Health Organization, 2014). Identifying risk factors at the individual, school and neighborhood level will help prevent the development of poor health outcomes such as diabetes and heart disease. The purpose of this study was to determine the associations between neighborhood deprivation, the retail food environment, obesity and physical fitness in children residing in El Paso, Texas. The study population included children in grades three through eight attending school in the El Paso Independent School District from 2009 to 2013. Approximately 42,000 student …

The Efficacy Of Baby Sign Language In Reducing Problem Behaviors In Typically Developing Children, Nguyen-Chau Dinh

Open Access Theses & Dissertations

Baby sign is an emerging trend that is speculated to reduce the instances of tantrums, emotional outbursts, and frustration in typically hearing infants (Nelson, White, & Grewe, 2012). Despite its proclaimed benefits, little research has been conducted to evaluate the true efficacy of baby sign in reducing problem behaviors in typically hearing children. The purpose of this study was to evaluate whether or not baby sign could be used as an alternative and augmentative communication modality in increasing communicative intent and decreasing stress. A single subject, AB design was used to examine the changes in behavior in a typically developing …

Process Evaluation Of The Batterer Intervention And Prevention Program Of The Center Against Sexual And Family Violence In El Paso, Texas, Kathleen Anne O'Connor

Open Access Theses & Dissertations

Background: Intimate partner violence (IPV) is a significant public health issue. One in five women and one in seven men will experience severe physical violence from an intimate partner in their lifetime in the US; and one in three women globally (Breiding, Basile, Smith, Black, & Mahendra, 2015; World Health Organization, 2017). Notwithstanding such stark statistics, there is a gap in research on batterers and on batterer intervention and prevention programs (BIPP). Purpose: Program processes related to follow-up of clients were evaluated at the Center Against Sexual and Family Violence Batterer Intervention and Prevention Program (CASFV BIPP) through a mixed-methods …

Multi-Antigen-Chemiluminescent-Elisa For The Diagnosis Of Trypanosoma Cruzi Infection In Chihuahua, Mexico., Jose Andrei Orozco

Open Access Theses & Dissertations

No abstract provided.

Does A Family History Of Type 2 Diabetes Affect Exercise Induced Improvements In Insulin Sensitivity, Metabolic Flexibility, And Myokine Expression In Mexican-American Males?, Manuel Amador

Open Access Theses & Dissertations

A family history of diabetes (FH+) is considered a risk factor for the development of insulin resistance and type 2 diabetes. However, it is not known whether exercise induced improvement in insulin sensitivity (IS) and metabolic flexibility (MF) are impacted by a FH+. Purpose: To determine if a FH+ limits exercise induced improvements in Insulin sensitivity, MF, body composition, and strength following an 8-week combined aerobic and resistance training intervention compared to those without a family history of diabetes (FH-). Methods: 19 (FH- n=9, age 21.89 ± 0.60 years, BMI 27.51 ± 1.68 kg/m2; FH+ n=10, age 23.41 ± 0.86 …

Supraclavicular Subclavian Access For Sapien Transcatheter Aortic Valve Replacement: A Novel Approach, Thom G. Dahle, John Castro, Jacob R. Dutcher, John M. Teskey, Wade Schmidt, Daren Danielson, Daniel Tiede

Articles

BACKGROUND:

Within the trans-subclavian approach, procedural techniques can vary widely, and reported access generally refers to an infraclavicular axillary approach. We describe and report the use of a novel supraclavicular true subclavian approach for transcatheter aortic valve replacement (TAVR) exclusively for implantation of Sapien 3 valves.

CASE PRESENTATION:

We report our first five consecutive patients undergoing TAVR with a Sapien 3 valve using a standardized subclavian approach at a single center. In-hospital and 30-day complications were reported. The use of this approach resulted in successful implantation in 100% of patients in a safe manner with 0% mortality, stroke, and vascular …

Comparative Analysis Of Low Molecular Weight Fraction Of Conditioned Media Derived From Starvation-Dormant And Anaerobically-Dormant Mycobacterium Avium Subsp. Paratuberculosis, Marina Buciuc

All Graduate Theses, Dissertations, and Other Capstone Projects

Johne's disease (JD) caused by Mycobacterium avium subsp. paratuberculosis (MAP) is a contagious chronic enteritis affecting all ruminants and causing economic loss of at least $250 million annually in the US dairy industry. One of the major limitations in the diagnosis of JD is the low sensitivity of fecal culture in animals with no clinical signs of the disease, but who are actively shedding MAP. Persistence of MAP in the host with no apparent signs of infection is attributed to its ability to enter a dormant state wherein the bacterium is viable, but is not able to replicate until conditions …

A Study Of Registered Nursing Students’ Perceptions Of Confidence In Providing Quality Nursing Care To Patients With Alzheimer’S Disease Or Other Dementia, Louanne E. Harto

Doctor of Education (Ed.D)

There are currently millions of persons living with Alzheimer’s disease or other dementia; a number that will rise as the older adult population increases. Patients with Alzheimer’s disease or other dementia who are admitted to the acute care hospital for a physical problem may not receive the same standard of care as those persons without a cognitive impairment. The purpose of this study was to explore the perceptions of students in a prelicensure registered nursing program regarding their confidence to provide patient-centered nursing care to patients with cognitive impairment, specifically Alzheimer’s disease or other dementia. This quantitative study used a …

Ethics And Cost-Effectiveness Of Naloxone, Allison Groch

Augustana Center for the Study of Ethics Essay Contest

This essay discusses the ethical components involved with using, distributing, and making naloxone readily available for reversing opioid overdoses. The cost-effectiveness of naloxone is also discussed as a reason why naloxone should be widely used in order to help fight the opioid epidemic.

Testing Cr(Ii)-Btc For Ammonia Adsorption Capabilities: A Research Proposal, Tyler Hemingway

Undergraduate Honors Theses

Excerpt from Purpose and Hypothesis

The purpose of this thesis is to determine the ability of a particular metal-organic framework (MOF), Cr(II)-BTC, to adsorb ammonia (NH₃) gas. This particular MOF was chosen for this study due to the Cr having open metal sites, which are generally suitable locations for ammonia adsorption as seen in other MOFs.^1,2,3 This study will be done by testing Cr(II)-BTC’s ability to adsorb as well as another MOFs ability to adsorb ammonia. From this data, the ability of Cr(II)-BTC to adsorb ammonia repeatedly and under dry or humid conditions will also be determined. …

Crash And Burnout: The Sophomore Slump In College Athletics, Jessica Ferguson

Undergraduate Honors Theses

This study analyzed and compared the severity of performance slumps of collegiate student-athletes in general and across academic years. The factors examined with performance slumps included athlete burnout, academic burnout, relationship satisfaction, and grade point averages. The first hypothesis was that reduced accomplishment scores from the athlete burnout questionnaire would indicate the severity of performance slumps. The results did not support the hypothesis. The second hypothesis was that the severity of performance slumps would positively correlate with academic burnout and negatively correlate with relationship satisfaction. The results supported this hypothesis. The third hypothesis was that student-athletes who experienced a performance …

A Comparison Of Hamstring Injury Recovery Rates In Male And Female Athletes, Amanda Hall

Undergraduate Honors Theses

Excerpt from Introduction

Hamstring injuries are among the most common muscular injuries sustained by athletes across multiple levels of various sports (Askling et al). Most hamstring injuries occur during similar movements and under similar conditions, where the muscle is required to be explosive. Thus, athletes that participate in sports where “sprinting, kicking, or high-speed skilled movements” are required, experience an increased likelihood of suffering a hamstring injury (Erickson and Sherry). After injury, athletes are then subjected to different methods of rehabilitation to heal and strengthen the afflicted area. However, some athletes take longer than others to return and impatience may …

I Survived The Icu: Post-Intensive Care Syndrome From Patient And Nursing Perspectives, Catherine Bynum

Undergraduate Honors Theses

Excerpt from Introduction

After a head-on collision with a drunk driver, Kathy Torpie had a long road to recovery ahead of her. After three weeks in the intensive care unit (ICU), sedation, and mechanical ventilation, she was left with a set of symptoms coined Post-Intensive Care Syndrome (PICS) (Torpie, 2005). PICS is defined as “a condition that encompasses new or worsening impairments in the patient’s physical, cognitive, or mental status arising after critical illness and persisting beyond the acute hospitalization” (Makic, 2016, p. 172). With technological advancements, ICU survival rates are on the rise. Now that survival has increased, it …

Regeneration Of Teeth And Periodental Tissues Using Stem Cells, Joshua A. Mckoy

Undergraduate Honors Theses

The purpose of this thesis is to serve as systematic literature review that provides a background on regenerative therapy in dentistry, as well as proposing the need for continued research. Regenerative dentistry has great potential for stem cell use. Stem cells of many types have the capability of self-renewal and differentiation into multiple cell types. With stem cell-based regeneration, dentistry can grow exponentially with the implementation whole-tooth replacement, pulp regeneration, periodontium regeneration, enamel regeneration, and dentin regeneration. Furthermore, utilizing various biomaterial scaffolds and inducing growth factor activity has been demonstrated to aid in regenerative efforts. Issues of regenerative therapies must …

Qualitative Analysis Of Grocery Store And Farmers Market Manager Perceptions Regarding Use Of Fruit And Vegetable Educational Materials, Lacey Mccormack, Shelly Brandenburger, Karlys Wells, Suzanne Stluka

Health and Nutritional Sciences Faculty Publications

The Pick it! Try it! Like it! (PTL) educational resource set, developed to display in grocery stores and farmers markets, teaches individuals how to shop for and prepare healthy fruit and vegetable dishes. Because program buy-in must be obtained from location managers before implementation occurs, the purpose of this study was to qualitatively examine the perceptions that grocery store and farmers market managers have regarding PTL implementation. Locations that requested PTL materials during 2013-14 were contacted and asked to answer 13 questions. Responses were analyzed using the content analysis method with themes generated and frequencies reported. Analyses examined manager perceptions …

Factors Influencing Choice Of Skilled Birth Attendance At Anc: Evidence From The Kenya Demographic Health Survey, Caroline Nyongesa, Xiaoyue Xu, John J. Hall, William Macharia, Faith Yego, Brigid Hall

Paediatrics and Child Health, East Africa

Background: In Kenya, skilled attendance at delivery is well below the international target of 90% and the maternal mortality ratio is high at 362 (CI 254–471) per 100,000 live births despite various interventions. The preventative role of skilled attendance at delivery makes it a benchmark indicator for safe motherhood.

Methods: Maternal health data from the Service Provision Assessment Survey, a subset of the 2010 Kenya Demographic Health Survey was analyzed. Logistic regression models were employed using likelihood ratio test to explore association between choice of skilled attendance and predictor variables.

Results: Overall, 94.8% of women are likely to seek …

Simulation Study Of Cdna Dataset To Investigate Possible Association Of Differentially Expressed Genes Of Human Thp1-Monocytic Cells In Cancer Progression Affected By Bacterial Shiga Toxins., Syed A Muhammad, Jinlei Guo, Thanh M Nguyen, Xiaogang Wu, Baogang Bai, X Frank Yang, Jake Y Chen

Articles, Abstracts, and Reports

Shiga toxin (Stxs) is a family of structurally and functionally related bacterial cytotoxins produced by Shigella dysenteriae serotype 1 and shigatoxigenic group of Escherichia coli that cause shigellosis and hemorrhagic colitis, respectively. Until recently, it has been thought that Stxs only inhibits the protein synthesis and induces expression to a limited number of genes in host cells, but recent data showed that Stxs can trigger several signaling pathways in mammalian cells and activate cell cycle and apoptosis. To explore the changes in gene expression induced by Stxs that have been shown in other systems to correlate with cancer progression, we …

Nonsurgical Treatment Of An Adult Patient With Bilateral Scissors-Bite And Class Ii Division 2 Malocclusion, Wei-Cheng Fu, Yu-Ling Cheng, Chia-Yi Pan, Ming-Juean Su, Yuen-Yung Tsang

Taiwanese Journal of Orthodontics

This report illustrates a 20 years old female presented a Class II division 2 malocclusion with deep overbite, gummy smile, canted maxillary anterior occlusal plane, low mandibular plane angle and bilateral scissors-bite. Angle's Class II division 2 malocclusion needs to be treated by correcting the inclination of maxillary incisors and lower lip posture. Selective bonding of maxillary anterior teeth and molars were performed to level the occlusal plane and gingival line, thus creating a consonant smile arc. Disocclusion was necessary by using a removable bite plate. Maxillary second premolars and second molars, lower third molars were extracted. The aim was …

Etsu Health Annual Report - 2018, 2018

ETSU Health Annual Reports

No abstract provided.

Can Women Live With More Symptoms Than Men?: Defining Gender Differences In The Patient Acceptable Symptom State (Pass) In Orthopaedic Foot And Ankle Surgery, Judith Baumhauer, Adolph Flemister, Irvin Oh, Benedict Digiovanni, Jeff Houck

Faculty Publications - College of Physical Therapy

Introduction/Purpose: Over the last few years an increasing focus has been directed to define cut-off points for important health improvement. Minimal clinically important difference (MCID) values have traditionally been used to determine if a statistical change translates to a clinical improvement to the patient. Although MCID is helpful, it may be even more important to identify if the current treatment is adequate or that the patient has achieved an acceptable symptom state (symptoms minimal enough to live with). The purpose of this study was to determine if gender influenced patient reported outcomes (patient acceptable symptom state (PASS) and PROMIS Physical …

Ability Of Patient-Reported Outcomes To Characterize Patient Acceptable Symptom State (Pass) After Attending A Primary Care Physical Therapist And Medical Doctor Collaborative Service: A Cross-Sectional Study, Jeff Houck, Daniel Kang, Tyler Cuddeford, Sarah Rahkola

Faculty Publications - College of Physical Therapy

Objectives: To determine if the Patient-Reported Outcome Measurement Information System (PROMIS) physical function, pain interference, self-efficacy, and global rating of normal function (GRNF) scales are able to accurately characterize a patient’s acceptable symptom state (PASS).

Design: A cross-sectional analysis, using receiver operator curves and chi-square analysis to explore criteria to determine thresholds (80% and 95% sensitivity/specificity) for PASS that are applicable to PROMIS and GRNF scales.

Setting: Phone survey after primary care. Participants: Patients (NZ94) attending primary care for musculoskeletal problems. Interventions: Not applicable. Main Outcomes Measures: Accuracy and proportion of patients classified as PASS Yes or No.

Results: Receiver …

Comparison Of Jump And Hop Test Measures Between Naia And Division Iii Male Collegiate Basketball Players, Jason Brumitt, Amy Engilis, Alma Mattocks, Natalie Ellis, Jordon Reyes

Faculty Publications - College of Physical Therapy

Purpose: To report normative data for two functional performance tests (FPTs) (the standing long jump [SLJ] and the single-leg hop [SLH]) in a population of male collegiate basketball players and to identify differences in measures between athletes based on level of competition, starter status, and position.

Methods: Eighty-six male collegiate basketball players from six teams were recruited for this study. Each athlete performed three SLJs and three SLHs (bilaterally).

Results: Mean (± SD) FPT measures (normalized to height) for all basketball players were: SLJ = 1.0 ± 0.1, right SLH = 0.84 ± 0.1, and left SLH = 0.85 ± …

Asymmetry After Hip Fracture: A Multi-Factorial Problem, Andrew J. Meszaros, Cindy Zablotny, Paul A. Shew, Bret Reordan

Faculty Publications - College of Physical Therapy

Background and Purpose: Sit-to-stand (STS) and static standing mechanics are related to fall risk and function after hip fracture. Often, these patients avoid weight bearing on the fracture side after rehabilitation. The purpose of this study was to use a novel clinically-relevant protocol to examine standing and STS vertical ground reaction force (vGRF) in light of perceptual measures of loading symmetry and muscle torque production in this population. Methods: A person post hip fracture performed 3 different STS conditions and 2 simple load-matching tasks. Motion, force plate, and perceptual data on weight distribution and load were collected. Findings: Standing and …

What Maximum Ankle Torque Is Appropriate For Training Patients With Non-Insertional Achilles Tendinopathy?, Tyler Cuddeford, Jeff Houck, Derek Palmer, Jason Beilstein, Jordan Visser

Faculty Publications - College of Physical Therapy

Background and Purpose: The capacity of the Achilles tendon during a 1-repetition eccentric maximum contraction is largely unknown. This study examined the maximum ankle torque during a concentric/ eccentric heel raise/lowering task and while running in healthy individuals and participants with chronic Achilles tendinopathy. These findings were applied to a 10-week training program for a patient with chronic Achilles tendinopathy.

Methods: A total of 13 subjects (9 healthy and 4 with Achilles tendinopathy) participated in this study. Subjects were asked to perform a maximum eccentric contraction wearing a weighted vest while collecting 3-dimensional biomechanical variables. Subjects also ran along an …

A Study Of Outcomes Following Collaborative Medical Doctor/Physical Therapist Primary Care Service For Musculoskeletal Problems, Daniel Kang, Sarah Rahkola, Catherine Vandehaar, Andrea Mulligan, Kevin Morikawa, Amador Marcano, Tyler Cuddeford, Jeff Houck

Faculty Publications - College of Physical Therapy

Background and Purpose: Collaborative medical doctor/physical therapist primary care services are not described in the literature. The 2 purposes of this observational study were to describe a collaborative medical doctor/physical therapist primary care service, and to describe simple, one question, outcomes including patient acceptable symptom state (PASS), global rating of normal function (GRNF), and success of treatment (SOT) at intake, 1 to 7 days, and 45 to 60 days follow-up. Methods: Patients were seen for 1 to 2 visits and typically received exercise, hands on treatment, ie, manual therapy, and education. Medical doctor/physical therapist collaborative encounters and provider training are …

A Word From The Writing Center (January 2018), Jennifer Wilson, Ms, Els

A Word From the Writing Team (Newsletter)

This issue includes:

• New Year, New Publishing Goals
• Grammar Time
• Writing Cafe

Does The Foundational Model Of Anatomy Ontology Provide A Knowledge Base For Learning And Assessment In Anatomy Education?, Melissa D. Clarkson, Mark E. Whipple

Institute for Biomedical Informatics Faculty Publications

Throughout the development of the Foundational Model of Anatomy (FMA) ontology, one of the use cases put forth has been anatomy education. In this work, we examine which types of knowledge taught to anatomy students can be supported by the FMA knowledge base. We first categorize types of anatomical knowledge, then express these patterns in the form “Given ____, state ____”. Each of the 33 patterns was evaluated for whether this type of knowledge is compatible with the modeling and scope of the FMA.