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2018

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Articles 10951 - 10980 of 15441

Full-Text Articles in Medicine and Health Sciences

Evolution Of Occupational Therapy Practice: Life History Of Janeene Sibla Otd, Otr/L, Sara Anderson, Colter Pettit Jan 2018

Evolution Of Occupational Therapy Practice: Life History Of Janeene Sibla Otd, Otr/L, Sara Anderson, Colter Pettit

Oral History Student Papers

Objective: The purpose of this life history of Janeene Sibla was to provide current and future occupational therapist an overview of her journey as an occupational therapist in North Dakota. This life history also looks at the historical events that influenced the occupational therapy profession and Janeene. This life history was one of 31 done for a course at the University of North Dakota.

Method: The project directors reached out to occupational therapists and certified occupational therapy assistants in North Dakota and Wyoming. Janeene was assigned by the project directors to the researchers. A semi-structured recorded phone interview that lasted …


Evolution Of Occupational Therapy Practice: Life History Of Jan Nelson, Otr/L, Ma, Jessica Anderson, Reghan Boldt Jan 2018

Evolution Of Occupational Therapy Practice: Life History Of Jan Nelson, Otr/L, Ma, Jessica Anderson, Reghan Boldt

Oral History Student Papers

Objective. The purpose of this qualitative study was to gather information about the history and evolution of occupational therapy (OT) practice, guided by the Kawa Model. The life history of Jan Nelson was one of 31 life history interviews conducted apart of a larger project of Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy in North Dakota and Wyoming.

Method. An hour and a half semi-structured interview was completed with Jan Nelson and two OT student researchers. From the interview data, the student researchers created themes that were meaningful to Jan Nelson’s life and OT career. …


Evolution Of Occupational Therapy Practice: Life History Of Diane Mccormack, Ms, Otr/L, Karen Jaspers, Alyssa Turner-Strong Jan 2018

Evolution Of Occupational Therapy Practice: Life History Of Diane Mccormack, Ms, Otr/L, Karen Jaspers, Alyssa Turner-Strong

Oral History Posters

This is one of 31 life history interviews which are part of a larger project, Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy (OT) in North Dakota and Wyoming. The purpose of this project is to gather information about the history and evolution about occupational therapy (OT) practice in North Dakota and Wyoming through life histories of individuals who have been influential in developing OT in these two states. This study is intended to provide current and future generations of occupational therapists a view of the history and how occupational therapy practice has evolved from its …


Evolution Of Occupational Therapy Practice: Life History Of Sue Hamilton, Cota/L, Karlie Marler, Meagan Flom Jan 2018

Evolution Of Occupational Therapy Practice: Life History Of Sue Hamilton, Cota/L, Karlie Marler, Meagan Flom

Oral History Posters

This life history one of 31 life history interviews which are a part of a larger project, Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy (OT) in North Dakota and Wyoming, The purpose of the project is to gather information about the history and evolution of occupational therapy (OT) practice in North Dakota and Wyoming through life histories of individuals who have been influential in developing OT in these two states. It is anticipated that the life history process will be a powerful way to gather this information. This study is intended to provide current and …


Interaction Between Body Talk In Romantic Relationships And Body Dissatisfaction On Unhealthy Body Change Behaviors, Lillian Ellis Jan 2018

Interaction Between Body Talk In Romantic Relationships And Body Dissatisfaction On Unhealthy Body Change Behaviors, Lillian Ellis

Master's Theses and Doctoral Dissertations

Unhealthy body change behaviors, such as eating disorder symptoms and muscle dysmorphia symptoms, can cause serious harm in individuals’ lives, impacting physical and emotional health. Body change behaviors have been shown to be associated with body dissatisfaction and body talk. However, individuals’ body talk with their romantic partner has not been well examined. The current study investigated the relationships between body talk with a romantic partner, gender, and body dissatisfaction with body change strategies, using a hierarchical regression that included direct relationships and interaction effects. Participants were college students who took an online study for class credit. Body dissatisfaction and …


Catching Up To Multiculturalism: Bilingual And Cultural Competent Practices In Speech-Language Pathology, Yeji (Loris) Yoon Jan 2018

Catching Up To Multiculturalism: Bilingual And Cultural Competent Practices In Speech-Language Pathology, Yeji (Loris) Yoon

Master's Theses and Doctoral Dissertations

The rapid rise of culturally and linguistically diverse (CLD) clients has resulted in an increased demand for bilingual speech-language pathologists (SLPs) in schools and health care settings. Yet little is known about the experiences and the training needs of these bilingual service providers. This qualitative study used in-depth interviews with seven bilingual SLPs to highlight their perspectives on bilingualism and provision of bilingual speech-language pathology services. Participants reported the value of being a bilingual and took pride in having these skills to help people communicate but noted the gap between their graduate training and clinical experiences in working bilingually due …


Relationships Among Apathy, Health-Related Quality Of Life, And Function In Huntington's Disease., Nora E Fritz, Nicholas R Boileau, Julie C Stout, Rebecca Ready, Joel S Perlmutter, Jane S Paulsen, Kimberly Quaid, Stacey Barton, Michael K Mccormack, Susan L Perlman, Noelle E Carlozzi Jan 2018

Relationships Among Apathy, Health-Related Quality Of Life, And Function In Huntington's Disease., Nora E Fritz, Nicholas R Boileau, Julie C Stout, Rebecca Ready, Joel S Perlmutter, Jane S Paulsen, Kimberly Quaid, Stacey Barton, Michael K Mccormack, Susan L Perlman, Noelle E Carlozzi

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Up to 90% of individuals with Huntington's disease (HD)-a progressive, inherited neurodegenerative disorder-experience apathy. Apathy is particularly debilitating because it is marked by a reduction in goal-directed behaviors, including self-care, social interactions, and mobility. The objective of this study was to examine relationships between variables of apathy, functional status, physical function, cognitive function, behavioral status/emotional function, and health-related quality of life. Clinician-rated measures of physical, cognitive, and behavioral function, including one clinician-rated item on apathy, and self-reported measures of physical function, health-related quality of life, and emotional, cognitive, and social function were collected in a single session from 487 persons …


Project Rafiki: Consumer And Provider Perspectives On Food Assistance And Its Impact On Quality Of Life For Individuals Living With Hiv/Aids, Emily C. Holderfield-Gaither, Saundra Starks, William Mkanta Jan 2018

Project Rafiki: Consumer And Provider Perspectives On Food Assistance And Its Impact On Quality Of Life For Individuals Living With Hiv/Aids, Emily C. Holderfield-Gaither, Saundra Starks, William Mkanta

Contemporary Rural Social Work Journal

Project Rafiki was designed to provide nonperishable food assistance to individuals living with HIV/AIDS in Tanzania, East Africa. The research study was developed to examine the extent to which the Project Rafiki food assistance program had impacted its participants over the course of one year. The aim of this research can be divided into five smaller objectives: 1) to gage the effectiveness of the food assistance program; 2) to assist in the expansion of inter-professional knowledge of resource-development regarding health and nutrition for vulnerable communities or rural areas; 3) to involve and immerse students in learning on a global level; …


Using Person-Centered Scheduling With Geriatric Patients To Reduce Anxiety With Telepsychiatry, Jody G. Long, Patricia A. Wilkerson, Evi Taylor, John H. Hall, Christopher Peters Jan 2018

Using Person-Centered Scheduling With Geriatric Patients To Reduce Anxiety With Telepsychiatry, Jody G. Long, Patricia A. Wilkerson, Evi Taylor, John H. Hall, Christopher Peters

Contemporary Rural Social Work Journal

ABSTRACT

Objective: This study explored using person-centered scheduling with telepsychiatry for rural community geriatric patients. Quantitative research approaches were used to determine the level of satisfaction participants experienced with person-centered scheduling and geriatric telepsychiatry. Method: Quantitative data were collected by using the Zung Self-Rating Anxiety Scale (SAS) before scheduling the first appointment and to assess the intervention’s effectiveness after the telepsychiatry session. Results: Person-centered telepsychiatry scheduling decreased geriatric patients’ anxiety as evidenced by Zung SAS scores. Conclusion: Older adult patients saw telepsychiatry as a viable means of treatment. Future research with geriatrics from different regions is needed.

Implications and future …


Exploring The Regulatory Mechanism Of The Notch Ligand Receptor Jagged1 Via The Aryl Hydrocarbon Receptor In Breast Cancer, Sean Alan Piwarski Jan 2018

Exploring The Regulatory Mechanism Of The Notch Ligand Receptor Jagged1 Via The Aryl Hydrocarbon Receptor In Breast Cancer, Sean Alan Piwarski

Theses, Dissertations and Capstones

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that binds pollutants, therapeutic drugs and endogenous ligands. AHR is of particular interest in cancer and has been shown to play roles in both tumor progression and tumor suppression. As a result, it has received growing attention as a possible chemotherapeutic target. AHR is expressed in all breast cancer subtypes and can promote or inhibit breast cancer depending on the ligand it binds. The Notch signaling pathway is a highly conserved evolutionary pathway that plays extremely vital roles during development by regulating cell fate and differentiation. Notch signaling has increasingly …


Simultaneous Avulsion Fractures Of The Tibial Tuberosity Of Both Knees In A 14-Year-Old Boy: A Case Report, Margaret E. Pusateri, Selina R. Silva, Christopher A. Mcgrew Jan 2018

Simultaneous Avulsion Fractures Of The Tibial Tuberosity Of Both Knees In A 14-Year-Old Boy: A Case Report, Margaret E. Pusateri, Selina R. Silva, Christopher A. Mcgrew

UNM Orthopaedic Research Journal

Fractures of the tibial tuberosity are uncommon injuries in adolescents, representing an estimated 0.4% to 2.7% of all pediatric fractures. Most of these injuries occur in young, active males commonly between the ages of 12 to 17 years. Sports, particularly those involving jumping or sudden starts and stops, are most often implicated. Injuries of the tibial tuberosity of both knees are especially rare, with little more than 30 cases reported in the past 60 years. We present a 14-year-old male football player with simultaneous avulsion fractures of the tibial tuberosity of both knees. We reviewed the anatomy, mechanisms of injury, …


Letter From The Residency Director, Unm Department Of Orthopaedic Surgery Jan 2018

Letter From The Residency Director, Unm Department Of Orthopaedic Surgery

UNM Orthopaedic Research Journal

No abstract provided.


Conservative Treatment Of A 58 Year-Old Male Referred To Physical Therapy With A Knee Sprain And Knee Osteoarthritis, Chase Pruitt Jan 2018

Conservative Treatment Of A 58 Year-Old Male Referred To Physical Therapy With A Knee Sprain And Knee Osteoarthritis, Chase Pruitt

Physical Therapy Scholarly Projects

Background and Purpose: Knee osteoarthritis (OA) is a common condition in people over 50. Although there may be an association between acute knee injuries and knee OA later in life, the occurrence of acute knee injuries in patients with existing OA is less clear. The purpose of this case study is to evaluate the effectiveness of an impairment based therapy program in an individual with an acute knee injury and knee OA.

Case Description: This case follows a 57 year old male referred to physical therapy with an acute knee sprain and tri-compartmental knee OA. Treatment lasted 7 sessions …


A Case Report: Outpatient Physical Therapy Treatment Of A Patient With Unilateral Medial And Posterior Knee Pain And Osteoarthritis, Joseph T. Griffin Jan 2018

A Case Report: Outpatient Physical Therapy Treatment Of A Patient With Unilateral Medial And Posterior Knee Pain And Osteoarthritis, Joseph T. Griffin

Physical Therapy Scholarly Projects

Background & purpose: Meniscus tears are commonly considered to be associated with a traumatic event, but the degenerative nature of osteoarthritis can also damage the cartilage. As meniscal tears are a common orthopedic pathology, choosing the correct treatment can be difficult and involve several factors. Current treatment options include partial or total meniscectomy, meniscal repair, or conservative management. There is growing research supporting the effectiveness in non-operative management of degenerative meniscal tears (DMT). The purpose of this case report was to investigate the non-operative management of a 47-year-old male with a unilateral DMT combined with osteoarthritis.

Case description: …


Physical Therapy Intervention In A Patient With West Nile Meningitis: A Case Approach, Kelsie Gunnufson Jan 2018

Physical Therapy Intervention In A Patient With West Nile Meningitis: A Case Approach, Kelsie Gunnufson

Physical Therapy Scholarly Projects

Background and Purpose. West Nile Virus (WNV) is a neurotropic virus capable of causing damage of varying severity. WNV is commonly transmitted to humans from mosquitoes and is most prevalent in the months of August and September due to the method of transmission. The WNV can produce mild systemic symptoms classified as West Nile Fever (WNF). However, it can progress and infiltrate the nervous system, at which point the virus is categorized as neuroinvasive. One classification is West Nile Meningitis (WNM) that involves infection and inflammation of the meninges or coverings surrounding the brain and spinal cord. There is …


Collaboration Of Music Therapy And Physical Therapy: A Case Study For Treatment Of A Patient With Chronic Stroke, Matthew Aymond, Michelle Sanders Jan 2018

Collaboration Of Music Therapy And Physical Therapy: A Case Study For Treatment Of A Patient With Chronic Stroke, Matthew Aymond, Michelle Sanders

Physical Therapy Scholarly Projects

Background and Purpose: Stroke is one of the leading causes of death in the United States and can cause severe, debilitating, and lasting effects. Although a fair amount of research has been performed on treatment of individuals following a stroke, few studies exist looking at the collaborative efforts of physical therapy and music therapy.

Case Description: This case follows the 13-week interdisciplinary care of an 83-year old female patient with chronic impairments following a cerebrovascular accident suffered approximately 2 years prior.

Interventions: Following an initial evaluation, the patient performed 11 one-hour treatment sessions over an 11-week period. …


The Effect Of Socket Tightness In Femur Stability In A Hifi Socket, Mary Bachman, Alicia Beckel, Amanda Belyaks Jan 2018

The Effect Of Socket Tightness In Femur Stability In A Hifi Socket, Mary Bachman, Alicia Beckel, Amanda Belyaks

Physical Therapy Scholarly Projects

Background and Purpose: The introduction of the High-Fidelity (HiFi) interface was developed to help increase the intimacy of the prosthetic interface by using a series of alternating zones of tissue compression and release. The purpose of this study was to utilize motion analysis to measure the stability of the femur in individuals with trans-femoral amputation that utilize the HiFi socket for ambulation.

Methods: The subject was a 62 year old Caucasian female. She had a trans-femoral amputation 35 years prior due to a diagnosis of cancer located in the bone of her femur. Data collection was done with …


Association Of Generalized Joint Hypermobility And The Occurrence Of Musculoskeletal Work-Related Injury In The First Zero To Five Years Of Physical Therapy Practice: A Pilot Study, Mikelle Fetsch, Ashley Naas, Amanda Slaikeu Jan 2018

Association Of Generalized Joint Hypermobility And The Occurrence Of Musculoskeletal Work-Related Injury In The First Zero To Five Years Of Physical Therapy Practice: A Pilot Study, Mikelle Fetsch, Ashley Naas, Amanda Slaikeu

Physical Therapy Scholarly Projects

Background: Previous research has shown that there is greater prevalence of work-related injuries for Physical Therapists in their early years of practice. However, little evidence has focused on the correlation with the high physical strain and stress of the job to the rate of injury occurrence. Hypermobility has also been researched in regards to an increased risk of sustaining an injury, but no correlation has been found between hypermobility and work-related injury in Physical Therapists.

Purpose: The purpose of this study was to determine if there is a correlation between hypermobility and work-related injury occurrence in the first …


Circulation First – The Time Has Come To Question The Sequencing Of Care In The Abcs Of Trauma; An American Association For The Surgery Of Trauma Multicenter Trial, Paula Ferrada, Rachael A. Callcut, David J. Skarupa, Therese M. Duane, Alberto Garcia, Kenji Inaba, Desmond Khor, Vincent Anto, Jason Sperry, David Turay, Rachel M. Nygaard, Martin A. Schreiber, Toby Enniss, Michelle Mcnutt, Herb Phelan, Kira Smith, Forrest O. Moore, Irene Tabas, Joseph Dubose, Aast Multi-Institutional Trials Committee Jan 2018

Circulation First – The Time Has Come To Question The Sequencing Of Care In The Abcs Of Trauma; An American Association For The Surgery Of Trauma Multicenter Trial, Paula Ferrada, Rachael A. Callcut, David J. Skarupa, Therese M. Duane, Alberto Garcia, Kenji Inaba, Desmond Khor, Vincent Anto, Jason Sperry, David Turay, Rachel M. Nygaard, Martin A. Schreiber, Toby Enniss, Michelle Mcnutt, Herb Phelan, Kira Smith, Forrest O. Moore, Irene Tabas, Joseph Dubose, Aast Multi-Institutional Trials Committee

Surgery Publications

Background

The traditional sequence of trauma care: Airway, Breathing, Circulation (ABC) has been practiced for many years. It became the standard of care despite the lack of scientific evidence. We hypothesized that patients in hypovolemic shock would have comparable outcomes with initiation of bleeding treatment (transfusion) prior to intubation (CAB), compared to those patients treated with the traditional ABC sequence.

Methods

This study was sponsored by the American Association for the Surgery of Trauma multicenter trials committee. We performed a retrospective analysis of all patients that presented to trauma centers with presumptive hypovolemic shock indicated by pre-hospital or emergency department …


Training Neurodegenerative Disease Support Group Leaders: A New Support Group Functioning Scale, Therese V. Cash, Christopher Kilbourn, Sarah K. Lageman Jan 2018

Training Neurodegenerative Disease Support Group Leaders: A New Support Group Functioning Scale, Therese V. Cash, Christopher Kilbourn, Sarah K. Lageman

Neurology Publications

Support group leaders play pivotal roles in maintaining healthy community support groups; however, these leaders also have personal support needs and typically lack formal training in managing complex behaviors of neurodegenerative disorders. A support group well-being questionnaire, assessing support group functioning, was developed and piloted among participants of an educational training program designed for support group leaders of various neurodegenerative disorder-specific support groups. An exploratory factor analysis evaluated the questionnaire’s psychometric properties and identified a reliable single factor five-item solution, which was titled the Support Group Functioning Scale (SGFS). Preliminary interpretation guidelines were proposed. Development of this scale is a …


The Year In The Rear-View Mirror, Edward F. Ansello Jan 2018

The Year In The Rear-View Mirror, Edward F. Ansello

Director's Editorials from Age in Action

The year 2018 is the Virginia Center on Aging's 40th anniversary. Our programs and activities have evolved over time but we have remained true to the charges given us in the Code of Virginia, essentially to conduct interdisciplinary studies, including training practitioners and offering educational opportunities for older adults, conducting research on and advancing knowledge about dementia, and serving as an information resource to those committed to the well-being of older adults. Our current operations feature four program areas: abuse in later life (domestic violence and elder abuse); dementia research; geriatrics and gerontology education; and lifelong learning.


Association Between Breastfeeding Duration And Type Of Birth Attendant, Jordyn T. Wallenborn, Saba W. Masho Jan 2018

Association Between Breastfeeding Duration And Type Of Birth Attendant, Jordyn T. Wallenborn, Saba W. Masho

Family Medicine and Population Health Publications

Introduction. Healthcare providers play an integral role in breastfeeding education and subsequent practices; however, the education and support provided to patients may differ by type of provider. The current study aims to evaluate the association between type of birth attendant and breastfeeding duration. Methods. Data from the prospective longitudinal study, Infant Feeding Practices Survey II, was analyzed. Breastfeeding duration and exclusive breastfeeding duration were defined using the American Academy of Pediatrics’ national recommendations. Type of birth attendant was categorized into obstetricians, other physicians, and midwife or nurse midwife. If mothers received prenatal care from a different type of provider than …


Evaluation Of Image Registration Accuracy For Tumor And Organs At Risk In The Thorax For Compliance With Tg 132 Recommendations, Christopher L. Guy, Elisabeth Weiss, Shaomin Che, Nuzhat Jan, Sherry Zhao, Mihaela Rosu-Bubulac Jan 2018

Evaluation Of Image Registration Accuracy For Tumor And Organs At Risk In The Thorax For Compliance With Tg 132 Recommendations, Christopher L. Guy, Elisabeth Weiss, Shaomin Che, Nuzhat Jan, Sherry Zhao, Mihaela Rosu-Bubulac

Radiation Oncology Publications

Purpose
To evaluate accuracy for 2 deformable image registration methods (in-house B-spline and MIM freeform) using image pairs exhibiting changes in patient orientation and lung volume and to assess the appropriateness of registration accuracy tolerances proposed by the American Association of Physicists in Medicine Task Group 132 under such challenging conditions via assessment by expert observers.

Methods and Materials
Four-dimensional computed tomography scans for 12 patients with lung cancer were acquired with patients in prone and supine positions. Tumor and organs at risk were delineated by a physician on all data sets: supine inhale (SI), supine exhale, prone inhale, and …


Would You Recognize Lupus?, Sydney C. Smith, Maegan Simms, Barbara Brown Jan 2018

Would You Recognize Lupus?, Sydney C. Smith, Maegan Simms, Barbara Brown

Dental Hygiene Student Scholarship

Systemic Lupus Erythematosus, or SLE, is a chronic autoimmune disease which significantly affects various organs of the body and the oral cavity. According to various studies, SLE can cause an increased risk of periodontitis, fungal infections, and dental caries within the oral cavity. Periodontitis is an inflammatory condition mediated by an infectious etiology which affects the supporting tissues of the periodontium and alveolar bone. With SLE being an inflammatory condition as well, recent studies have emerged hypothesizing the possible association between SLE and periodontitis. Other effects on the oral cavity such as fungal infections including lichen planus and angular cheilitis …


Trends And Effects Of Pharmaceutical Dtca, Alberto Coustasse, P. Sathorn, William K. Willis Jan 2018

Trends And Effects Of Pharmaceutical Dtca, Alberto Coustasse, P. Sathorn, William K. Willis

Management Faculty Research

Purpose – The purpose of the review is to investigate the current trend of pharmaceutical Direct-to-Consumer Advertising (DTCA) in the US and its effect on patients, physicians, and drug utilization. DTCA by pharmaceutical firms may be defined as an attempt by pharmaceutical companies to advertise products directly to patients.

Design/methodology/approach – Methodology for this paper is a literature review approach.

Findings – Pharmaceutical DTCA demonstrated a reduction in total spending, while the online channel media experienced growth. DTCA has influenced the physician-patient relationship and patient satisfaction. Patients who received medication associated with DTCA showed higher satisfaction. DTCA of second-line drugs …


The Impact Of Big Data On Chronic Disease Management, Niharika Bhardwaj, Bezawit Wadajo, Anthony Spano, Alberto Coustasse Jan 2018

The Impact Of Big Data On Chronic Disease Management, Niharika Bhardwaj, Bezawit Wadajo, Anthony Spano, Alberto Coustasse

Management Faculty Research

Introduction: Population health management – and specifically chronic disease management – depend on the ability of providers to identify patients at high risk of developing costly and harmful conditions such as diabetes, heart failure, and chronic kidney disease (CKD). The advent of big data analytics could help identify high-risk patients which is really beneficial to healthcare practitioners and patients to make informed decisions in a timelier manner with much more evidence in hand. It would allow doctors to extend effective treatment but also reduces the costs of extending improved care to patients.

Purpose: The purpose of this study was to …


Graduate Admissions Recruitment Project, Kevin Anderson, Chiemela Dike, Yixin Du, Arvinder Kaur, Amanda Popp, Huizhong Yang Jan 2018

Graduate Admissions Recruitment Project, Kevin Anderson, Chiemela Dike, Yixin Du, Arvinder Kaur, Amanda Popp, Huizhong Yang

School of Professional Studies

In this project, several comparison schools were interviewed and disclosed to have used search lists to find candidates. The organizations that have valuable search lists which may be of good use for the School of Professional Studies include Educational Testing Service (ETS) and the Graduate Management Admission Council (GMAC). By choosing criteria such as demographics, location, academic performance, educational history provided by search lists, we believe there are many quality candidates for SPS programs. However, as we further investigated the functionality and cost-efficiency or return of investment of GRE search list, we spotted many uncertainties and few solid and successful …


A Gut Feeling: A Hypothesis Of The Role Of The Microbiome In Attention-Deficit/Hyperactivity Disorders., Xue Ming, Neil Chen, Carly Ray, Gretchen Brewer, Jeffrey Kornitzer, Robert A Steer Jan 2018

A Gut Feeling: A Hypothesis Of The Role Of The Microbiome In Attention-Deficit/Hyperactivity Disorders., Xue Ming, Neil Chen, Carly Ray, Gretchen Brewer, Jeffrey Kornitzer, Robert A Steer

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Attention-deficit/hyperactivity disorder (ADHD) is a neurologic disorder characterized by hyperactivity/impulsivity and/or inattentiveness, with genetic and environmental factors contributing to the disorder. With the growing recognition of the microbiome's role in many neurological disorders, the authors propose that it may also be implicated in ADHD. Here, we describe several evolving areas of research to support this hypothesis. First, a unique composition of gut bacteria has been identified and linked to behaviors in ADHD. Second, our research found an increased incidence of 2 gastrointestinal symptoms (constipation and flatulence) in children with ADHD, as compared to controls. Finally, emerging data may be interpreted …


Bill Gatton College Of Pharmacy Economic Impact Report - 2018, Bill Gatton College Of Pharmacy, East Tennessee State University Jan 2018

Bill Gatton College Of Pharmacy Economic Impact Report - 2018, Bill Gatton College Of Pharmacy, East Tennessee State University

Bill Gatton College of Pharmacy Miscellaneous Publications

No abstract provided.


Oligomerization Of Bacterially Expressed H1n1 Recombinant Hemagglutinin Contributes To Protection Against Viral Challenge, Tess E. Kuenstling, Anthony R. Sambol, Steven H. Hinrichs, Marilynn A. Larson Jan 2018

Oligomerization Of Bacterially Expressed H1n1 Recombinant Hemagglutinin Contributes To Protection Against Viral Challenge, Tess E. Kuenstling, Anthony R. Sambol, Steven H. Hinrichs, Marilynn A. Larson

Journal Articles: Pathology and Microbiology

Vaccination is the most effective intervention to prevent influenza and control the spread of the virus. Alternatives are needed to the traditional egg-based vaccine strategy for a more rapid response to new outbreaks. Two different hemagglutinin (HA) fragments (rHA11-326 and rHA153-269) derived from influenza A virus subtype H1N1 were expressed in Escherichia coli and characterized by immunoblot, gel filtration, hemagglutination, and competitive binding assays. rHA11-326 included neutralizing epitopes and the trimerization domain, whereas rHA153-269 included only the head of HA with the neutralizing epitopes. Mice were immunized with rHA11-326 or rHA153-269, and …