Medicine and Health Sciences Commons^™

Toxicology Of Engineered Nanoparticles: Focus On Poly(Amidoamine) Dendrimers, Pratap Naha, Sourav Prasanna Mukherjee, Hugh Byrne

Articles

Engineered nanomaterials are increasingly being developed for paints, sunscreens, cosmetics, industrial lubricants, tyres, semiconductor devices, and also for biomedical applications such as in diagnostics, therapeutics, and contrast agents. As a result, nanomaterials are being manufactured, transported, and used in larger and larger quantities, and potential impacts on environmental and human health have been raised. Poly(amidoamine) (PAMAM) dendrimers are specifically suitable for biomedical applications. They are well-defined nanoscale molecules which contain a 2-carbon ethylenediamine core and primary amine groups at the surface. The systematically variable structural architecture and the large internal free volume make these dendrimers an attractive option for drug …

Improved Removal Of Blood Contamination From Thinprep Cervical Cytology Camples For Raman Spectroscopic Analysis, Damien Traynor, Shiyamala Duraipandian, C.Ara M. Martin, John J. O'Leary, Fiona Lyng

Articles

There is an unmet need for methods to help in the early detection of cervical precancer. Optical spectroscopy-based techniques, such as Raman spectroscopy, have shown great potential for diagnosis of different cancers, including cervical cancer. However, relatively few studies have been carried out on liquid-based cytology (LBC) pap test specimens and confounding factors, such as blood contamination, have been identified. Previous work reported a method to remove blood contamination before Raman spectroscopy by pretreatment of the slides with hydrogen peroxide. The aim of the present study was to extend this work to excessively bloody samples to see if these could …

Life Partner Perceptions Of The Emotional Impact Of Stuttering, Athanasia Svenning

Electronic Theses and Dissertations

The aim of the present study is to investigate the extent to which life partners understand the emotional impact stuttering has on their loved one who stutters. This was accomplished by administering the Speech Situation Checklist - Emotional Reaction (SSC-ER), a subtest of the Behavior Assessment Battery (BAB; Vanryckeghem & Brutten, 2018) via Qualtrics, an online survey software, to the participants who stutter and a modified version of the SSC-ER to their life partner. No significant differences and a positive correlation were observed between groups (people who stutter (PWS) and their life partner (LP) as it relates to total score …

Arabic Women’S Experience Of Childhood Sexual Abuse: A Mixed-Methods Study, Shahrazad Mahmoud Timraz

Wayne State University Dissertations

Background and purpose: Childhood sexual abuse (CSA) is an existing social problem that affects children worldwide, leading to poor psychological outcomes in adulthood. Childhood adversities including CSA account for 44.6% of childhood and 26%–32% of adult-onset psychiatric disorders. Furthermore, CSA is the second leading cause of posttraumatic stress disorder (PTSD) and influences an array of other outcomes such as depression, anxiety, hostility, and low self-esteem. Worldwide, approximately 8%–13% of girls have experienced sexual abuse. According to the few studies conducted in Arabic countries, CSA ranges from 7%–27%. Coping with CSA is a well-studied factor in regard to its impact on …

Airway Pressure Release Ventilation In Pediatric Acute Respiratory Distress Syndrome. A Randomized Controlled Trial, Saptharishi Lalgudi Ganesan, Muralidharan Jayashree, Sunit Chandra Singhi, Arun Bansal

Data and Test Instruments

No abstract provided.

An Adult With A Remnant Urachus Anomaly Diagnosed In The Emergency Department., Alan Lucerna, James Lee, James Espinosa, Risha Hertz, Victor Scali

Rowan-Virtua School of Osteopathic Medicine Departmental Research

The urachus is a midline tubular structure that stretches from the apex of the bladder and connects to the umbilicus. Urachal remnants result from incomplete regression of the fetal urachus in infancy. We report the case of a 21-year-old male who presented to the emergency department with purulent drainage from his umbilicus in association with a chronic intermittent "pulling sensation" in the umbilicus and suprapubic areas. An infected urachal remnant was diagnosed and was treated with an oral antibiotic and ultimately with outpatient excision of the remnant. Such cases are rare but have the potential to progress to sepsis. In …

Implementation Climate And Time Predict Intensity Of Supervision Content Related To Evidence Based Treatment, Michael D Pullmann, Leah Lucid, Julie P Harrison, Prerna Martin, Esther Deblinger, Katherine S Benjamin, Shannon Dorsey

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Objective: Children infrequently receive evidence-based treatments (EBTs) for mental health problems due to a science-to-practice implementation gap. Workplace-based clinical supervision, in which supervisors provide oversight, feedback, and training on clinical practice, may be a method to support EBT implementation. Our prior research suggests that the intensity of supervisory focus on EBT (i.e., thoroughness of coverage) during workplace-based supervision varies. This study explores predictors of supervisory EBT intensity. Methods: Participants were twenty-eight supervisors and 70 clinician supervisees. They completed a baseline survey, and audio recorded supervision sessions over 1 year. Four hundred and thirty eight recordings were coded for supervision content. …

Suicidal Ideation Assessment In Individuals With Premanifest And Manifest Huntington Disease., Melissa Wesson, Nicholas R Boileau, Joel S Perlmutter, Jane S Paulsen, Stacey K Barton, Michael K Mccormack, Noelle E Carlozzi

Rowan-Virtua School of Osteopathic Medicine Departmental Research

BACKGROUND: Huntington disease (HD) is associated with increased risk of suicide.

OBJECTIVE: This study compares suicide ideation in HD to the general population, assesses factors associated with increased prevalence of suicidal thoughts, and compares clinician-rated to self-reported assessments of suicidal ideation.

METHODS: We examined 496 participants with premanifest or manifest HD. Clinician-rated suicidal ideation was measured using the Problem Behaviors Assessment - short form. Self-reported ideation was measured using two items from the HDQLIFE Concern with Death and Dying item bank. Independent sample t-tests were conducted to compare the prevalence of suicidal thoughts between our HD sample and the U.S. …

Evolution Of Occupational Therapy Practice: Life History Of Bonnie Setness, Cota, Ashley Malina, Marissa Jahnke

Oral History Posters

The life history of Bonnie Setness in one of 31 life history interviews which are a part of a larger project, Life Histories of Individuals Who Have Been Influenced in Developing Occupational Therapy (OT) in North Dakota and Wyoming. The purpose of the project is to gather information about the history and evolution of occupational therapy (OT) practice in North Dakota and Wyoming through life histories of individuals who have been influential in developing OT in these two states. It is anticipated that the life history process will be a powerful way to gather this information. This study is intended …

Evolution Of Occupational Therapy Practice: Life History Of Amanda Wahlin, Mot, Otr/L, Ramsey Gehring, Summer Miller

Oral History Student Papers

Objective: The purpose of this life history of Amanda Wahlin was to gather information about the history of occupational therapy in North Dakota and Wyoming, and how it has evolved over time.

Methods: A semi-structured 70-minute interview was conducted via Skype. The interview was then coded for categories and themes.

Results: Twelve codes were established leading to three emergent categories

. Values education, and practicing as an occupational therapist were identified as major themes in Amanda’s life. Through the development of these themes, it became clear that Amanda has had a significant and positive impact on her rural community.

Conclusion: …

Evolution Of Occupational Therapy Practice: Life History Of Diane Norell, Msw, Otr/L, Caelin Hansen, Jessie Zimmer

Oral History Student Papers

The purpose of this study was to gather information about the history and evolution of occupational therapy (OT) through the life history of Diane Norell, MSW, OTR/L, who has been influential in developing OT through her practice. The researchers conducted a semi-structured, one-and-a-half-hour phone interview with Diane. The interview was audio recorded and transcribed verbatim. The Kawa model was used to guide the research. Data analysis and a document review of Diane’s curriculum vitae (CV) were done to develop codes. From those codes, the categories of personal life, professional life, healthcare, and academia were developed along with corresponding themes and …

Life History Of Jeff Mcmenamy, Otr/L, Jenna Marton, Brittanie Schafer, Myah Vanwormer

Oral History Posters

The life history of Jeff McMenamy was one of 31 life history interviews conducted as apart of a larger project of Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy (OT) in North Dakota and Wyoming. The purpose of this life history is to gain information on an individual in Wyoming or North Dakota who has been instrumental in developing occupational therapy. The study is intended to provide current and future generations of occupational therapists a view of the history and how OT practice has evolved evolved over time in North Dakota and Wyoming. The life history …

Evolution Of Occupational Therapy Practice: Life History Of Dr. Gail Bass, Phd, Otr/L, Kyler Peterson, Alisha Roberts

Oral History Student Papers

Objective. The purpose of this qualitative Life History study is to gather information about the evolution and history of occupational therapy (OT) practice from individuals who have been influential in developing OT.

Method. A one-hour, semi-structured interview was conducted with Dr. Gail Bass to gather information on her experiences in her works of occupational therapy. Once the interview was completed, it was transcribed verbatim by the researchers. Open coding was then used to identify codes, then categories, themes, and finally an overall assertion.

Results. Three major categories emerged from Dr. Bass' life history consisting of education, professional opportunities, and evolution. …

Evolution Of Occupational Therapy Practice: Life History Of Maggie Butler, Cota, Justine Flattum, Katie Stewart

Oral History Student Papers

Objective: This qualitative life history is part of a larger project that is aimed at gathering information about the history and evolution of occupational therapy in North Dakota and Wyoming. The purpose of this study is to gain a better insight of the influences that Maggie Butler has contributed to the occupational therapy profession.

Method: A semi-structured one hour interview was conducted with the participant and two researchers. The interview was transcribed and data was analyzed to produce codes, categories, themes, and a final assertion.

Results: The predominant categories that emerged from this process were: Path to COTA, Professional Development, …

Life History Of Janeene C. Sibla, Otd, Otr/L, Sara Anderson, Colter Pettit

Oral History Posters

This life history one of 31 life history interviews which are a part of a larger project, Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy (OT) in North Dakota and Wyoming. The purpose of the project is to gather information about the history and evolution of occupational therapy (OT) practice in North Dakota and Wyoming through life histories of individuals who have been influential in developing OT in these two states. The interviews were influenced by the Kawa model in that the researchers were looking at the river of Janeene Sibla and looking at parts of …

A Piece Of The Evolution Of Occupational Therapy In North Dakota: Life History Of Rhoda Erhardt, Ms, Otr/L, Faota, Sidney Carlson, Alexis Tyce

Oral History Posters

This life history is one of 29 life history interviews which are a part of a larger project, Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy in North Dakota and Wyoming. The purpose of the project is to gather information about the history and evolution of OT practice in North Dakota and Wyoming through life histories of individuals who have been influential in developing OT in these two states. It is anticipated that the life history process will be a powerful way to gather this information. By using a life history approach, this study focused on …

Effects Of Physical Therapy On An Elderly Patient With L5-S1 Radiculopathy: A Case Study, Mackenzie Mears

Physical Therapy Scholarly Projects

Background and Purpose. Low back pain is a major disabling diagnosis for adults over 60 with 36-70% suffering from this condition. There is little research demonstrating the effectiveness of physical therapy on the outcome of older patients with a lumbar disc herniation resulting in lumbosacral radiculopathy. The purpose of this scholarly project is to use a case report to explore the effectiveness of physical therapy in elderly patients with lumbosacral radiculopathy as the result of a L5-S1 disc herniation.

Case Description. The case study reviews an 81-year-old male who presented to physical therapy with insidious onset of left …

Examination Of Venous Thromboembolism Prophylaxis In Patients Undergoing Total Knee Arthroplasty, William Kucera

Physician Assistant Scholarly Project Posters

Elective total knee arthroplasty (TKA) is the most frequently performed inpatient surgical procedure in the United States (Kurtz, Ong, Lau, Mowat, & Halpern 2007). Complications of this procedure include deep vein thrombosis (DVT) and pulmonary embolism (PE), collectively referred to as venous thromboembolism (VTE). Various pharmacological agents exist for VTE prophylaxis. Warfarin and low-molecular-weight heparin (LMWH) were commonly used for VTE prophylaxis in the past, but with the emergence of novel anticoagulants including factor Xa inhibitors and direct thrombin inhibitors (DTIs), warfarin is used far less frequently. Aspirin is also approved for VTE prophylaxis. The purpose of this study was …

Associations Among Acne Vulgaris And Western Diet, Kate Meredith Suda

Physician Assistant Scholarly Project Posters

Acne vulgaris is one of the most common dermatologic conditions, especially among the adolescent population.

The pathogenesis of acne is largely multifactorial, with heredity and hormones strongly contributing to one’s risk of developing the chronic inflammatory skin condition.

High prevalence rates of acne in the adolescent population cannot be attributed to heredity alone, but by the influence of Western diet (WD) that overstimulates insulin-like growth factors (IGFs).

The purpose of this scholarly project is to determine if there is an association between the presence of acne vulgaris and the consumption of WD, and if a physiological link between the high …

Obesity: Modern Medicine Vs. Lifestyle, Jenny Christianson

Physician Assistant Scholarly Project Posters

Obesity is a rising epidemic, and is one of the most common, costly and preventable health problems the world is experiencing today (Center for Disease Control and Prevention, [CDC], 2017).

 From this, it is important to establish an effective treatment plan that can be implemented across the nation for maximum patient benefit.

 Lifestyle changes such as diet and exercise are important to any health care plan and are equally necessary to reduce health risks. However, in certain patients, lifestyle changes are not enough due to the maladaptive biologic process in their brain. Thus, additional treatment options need to …

Antibiotic Therapy In Preventing Exacerbations Of Severe Chronic Obstructive Pulmonary Disease, Jamie Trautner

Physician Assistant Scholarly Project Papers

Chronic obstructive pulmonary disease (COPD) is a progressive disease that has no cure but is treatable. The treatment goal is to have adequate symptom control, decreased exacerbations, prevent hospitalizations and maintain an independent quality of life. The above are attainable by lifestyle changes and pharmacotherapy. The review of literature is to determine if the benefits of long-term antimicrobial therapy outweigh the risks in the treatment of severe COPD. The search included PubMed, Cochrane and Clinical Key databases. Keywords searched include: chronic obstructive pulmonary disease, antibiotics, macrolides, antibacterial, azithromycin, bronchodilators, standard therapy, COPD exacerbations, adverse effects, and long-term. The gold standard …

Letrozole Vs. Clomiphene Citrate For Infertility In Polycystic Ovarian Syndrome, Kailey Potratz

Physician Assistant Scholarly Project Papers

Polycystic Ovarian Syndrome (PCOS) is the leading cause of anovulatory infertility and the most common endocrinopathy in women of reproductive age (Rosenfield & Ehrmann, 2016). It has been recognized that women with PCOS often struggle with infertility and require medication to stimulate ovulation to become pregnant. Currently, the first-line treatment for infertility associated with PCOS is clomiphene citrate, which was introduced in the 1960s (Morad & Farag, 2015). However, it has been proposed that an aromatase inhibitor, specifically letrozole, should become the first-line treatment for these patients due to a decreased adverse effect profile, a lower incidence of simultaneous multiple …

The Effectiveness Of Oral Non-Steroidal Anti-Inflammatories Versus Steroid Injections In Patients With Shoulder Pain, Darren Scott Pledger

Physician Assistant Scholarly Project Posters

- The fact that shoulder pain is the most common musculoskeletal complaint in primary care shows that clinicians must have an arsenal of quality interventions to treat this problem.

- The need for quality research and evidenced based guidelines are necessary to educate clinicians on their treatment options, the efficacy of those treatments, and their safety profiles.

Treatment Options For Hidradenitis Suppurativa: Efficacy, Risks, Benefits, Katherine A. Hennager

Physician Assistant Scholarly Project Posters

Hidradenitis suppurativa is a chronic, recurrent follicular occlusion disease with painful, sometimes debilitating, cutaneous draining lesions and subcutaneous abscesses (DynaMed Plus, 2016). Hidradenitis suppurativa is understood to be a multifactorial disease that is hard to treat in some patients, especially those with a severe form of the disease. For this project, the efficacy of adalimumab for hidradenitis suppurativa was assessed and whether it is more beneficial than traditional treatments used. Adalimumab is a TNF-alpha inhibitor which belongs to the biologic DMARDs drug class. Kimball et al. (2012) found that at week 16 of their trial 3.9% of the placebo patients, …

Comparing The Effectiveness Of A Low Carbohydrate Diet And Metformin On Glycosylated Hemoglobin Reduction In Type Two Diabetes Mellitus, Ashley Schultz

Physician Assistant Scholarly Project Posters

In this study, a low carbohydrate diet and metformin pharmacotherapy were compared to determine their effect on HbA1c in the type two diabetic patient. Several high quality studies were examined along with each treatment's effect on mainly HbA1c, but also other parameters such as body weight, cholesterol, and fasting and post prandial blood glucose levels. The study showed that both the low carbohydrate diet and metformin pharmacotherapy were effective at lowering HbA1c in the type two diabetic patient. The low carbohydrate diet showed a 0.2% increase in HbA1c all the way to a 2.2% decrease in baseline HbA1c in the …

Evaluation Of Occupational Therapy Practice: Life History Of Gail Bass, Phd, Otr/L, Kyler Peterson, Alisha Roberts

Oral History Posters

The life history of Dr. Gail Bass was one of 31 life history interviews conducted as part of a larger project of Life Histories of Individuals Who have Been Influential in Developing Occupational Therapy (OT) in North Dakota and Wyoming. The purpose of this Life History is to gather information about the evolution and history of OT practice from individuals who have been influential in developing OT. This study is intended to help current and future occupational therapists understand how the career has evolved throughout the existence of the profession. The life history of Dr. Gail Bass is a case …

Life History Of Diane Gunderson, Otr/L, Parker Hoey, Cheyenne Hanson

Oral History Posters

This life history is one of 31 life history interviews which are a part of a larger project, Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy (OT) in North Dakota and Wyoming. The purpose of the project is to gather information about the history and evolution of occupational therapy (OT) practice in North Dakota and Wyoming through life histories of individuals who have been influential in developing OT in these two states. It is anticipated that the life history process will be a powerful way to gather this information. This study is intended to provide current …

Evolution Of Occupational Therapy Practice: The Life History Of Tammy Olson, Cota, Noelle Rivard, Kelsey Wehe

Oral History Posters

Purpose

The life history of Tammy Olson was one of 31 life history interviews conducted for a larger project, Life Histories of Individuals Who Have Been Influential in Developing Occupational Therapy (OT) in North Dakota and Wyoming. The purpose of this study is to gather information about the history and evolution of OT practice in North Dakota and Wyoming through life histories of individuals who have been influential in developing OT in these two states. This study will provide current and future generations of occupational therapists and occupational therapy assistants a view of the history and how the profession has …

Evolution Of Occupational Therapy Practice: Life History Of Tammy Olson, Cota, Noelle Rivard, Kelsey Wehe

Oral History Student Papers

The purpose of this qualitative study was to gather information about the history and evolution of occupational therapy (OT) practice in North Dakota and Wyoming through life histories of individuals who have been influential in developing OT in these two states. This study focused on the life history of Tammy Olson, and her involvement and experiences in the evolution of OT practice. A face-to-face semi-standardized interview which lasted approximately one hour, along with the participant’s curriculum vitae (CV), was used to gather information. The interview was transcribed verbatim and analyzed to develop themes that reflected influential events, opportunities, and challenges …

Evolution Of Practice: Life History Of Jeff Mcmenamy, Jenna Marton, Brittanie Schafer, Myah Vanwormer

Oral History Student Papers

The purpose of this qualitative Life History project is to gather information about the history and evolution of occupational therapy practice in North Dakota and Wyoming through life histories of individuals who have been influential in developing occupational therapy in these two states. A onetime semi-structured interview was conducted with Jeff McMenamy, an occupational therapist in rural Wyoming. The questions were structured from an interview schedule that was provided by the project research directors, which was inspired by the Kawa model. In addition, the questions from the interview schedule were modified by the researchers to ask specific and applicable questions …