Medicine and Health Sciences Commons^™

Comparison Of Four Fitbit And Jawbone Activity Monitors With A Research-Grade Actigraph Accelerometer For Estimating Physical Activity And Energy Expenditure, Mary T. Imboden, Michael B. Nelson, Leonard A. Kaminsky, Alexander Hk Montoye

Faculty Publications - Department of Kinesiology

Background/aim Consumer-based physical activity (PA) monitors have become popular tools to track PA behaviours. Currently, little is known about the validity of the measurements provided by consumer monitors. We aimed to compare measures of steps, energy expenditure (EE) and active minutes of four consumer monitors with one research-grade accelerometer within a semistructured protocol.

Methods Thirty men and women (18–80 years old) wore Fitbit One (worn at the waist), Fitbit Zip (waist), Fitbit Flex (wrist), Jawbone UP24 (wrist) and one waist-worn research-grade accelerometer (ActiGraph) while participating in an 80 min protocol. A validated EE prediction equation and active minute cut-points were …

Peak Ventilation Reference Standards From Exercise Testing: From The Friend Registry, Leonard A. Kaminsky, Matthew P. Harber, Mary T. Imboden, Ross Arena, Jonathan Myers

Faculty Publications - Department of Kinesiology

Peak Ventilation Reference Standards from Exercise Testing: From the FRIEND Registry. Med. Sci. Sports Exerc., Vol. 50, No. 12, pp. 2603–2608, 2018. Purpose: Cardiopulmonary exercise testing (CPX) provides valuable clinical information, including peak ventilation (V˙ Epeak), which has been shown to have diagnostic and prognostic value in the assessment of patients with underlying pulmonary disease. This report provides reference standards for V˙ Epeak derived from CPX on treadmills in apparently healthy individuals. Methods: Nine laboratories in the United States experienced in CPX administration with established quality control procedures contributed to the Fitness Registry and the Importance of Exercise National Database …

Increase In Intra-Abdominal Pressure During Airway Suctioning-Induced Cough After A Successful Spontaneous Breathing Trial Is Associated With Extubation Outcome, Lonny Ashworth

Respiratory Therapy Faculty Publications and Presentations

Background: A patient’s ability to clear secretions and protect the airway with an effective cough is an important part of the pre-extubation evaluation. An increase in intra-abdominal pressure (IAP) is important in generating the flow rate necessary for a cough. This study investigated whether an increase from baseline in IAP during a coughing episode induced by routine pre-extubation airway suctioning is associated with extubation outcome after a successful spontaneous breathing trial (SBT).

Methods: Three hundred thirty-five (335) mechanically ventilated patients who passed an SBT were enrolled. Baseline IAP and peak IAP during successive suctioning-induced coughs were measured with a fluid …

Unpacking Action Research And Implementation Science: Implications For Nursing, Mary Casey, Denise O'Leary, David Coghlan

Articles

Aim

The aim of this study was to unpack the key concepts of action research and implementation science thereby enabling appropriate use of these methods in nursing.

Background

A key issue in action research is not so much the methodology employed to gather data/evidence but who decides the research agenda and who benefits from it. Implementation science is a way to ensure that evidence is translated into practice. The question arises as to how action research and implementation may be understood in relation to one another in nursing.

Design

Discussion Paper

Data sources

This discussion paper is based on our …

Developing And Sustaining Specialist And Advanced Practice Roles In Nursing And Midwifery: A Discourse On Enablers And Barriers, Gerard M. Fealy, Mary Casey, Denise O'Leary, Martin S. Mcnamara, Denise O'Brien, Laserina O'Conner, Rita Smith, Diarmuid Stokes

Articles

Aims and objectives

To collate, synthesise and discuss published evidence and expert professional opinion on enablers and barriers to the development and sustainability of specialist and advanced practice roles in nursing and midwifery.

Background

Expanded practice is a response to population health needs, healthcare costs and practitioners’ willingness to expand their scope of practice through enhanced responsibility, accountability and professional autonomy.

Design

This discursive paper is based on a rapid review of literature on enablers and barriers to the development and sustainability of specialist and advanced practice roles and is part of a wider policy analysis.

Methods

We analysed and …

2017-2018 Pediatric Subspecialty Trainees, Children's Mercy Hospital

Residents and Fellows Portraits

Photo composites of the graduate pediatric trainees in allergy/immunology, child abuse pediatrics, child neurology, clinical child psychology, clinical pharmacology, developmental-behavioral pediatrics, hospice & palliative care, laboratory genetics & genomics, neonatal-perinatal medicine, pediatric adolescent gynecology, pediatric anesthesiology, pediatric bioethics, pediatric cardiology, pediatric critical care medicine, pediatric dentistry, pediatric emergency medicine, pediatric endocrinology, pediatric gastroenterology, pediatric hematology/oncology, pediatric hospital medicine, pediatric infectious diseases, pediatric nephrology, pediatric optometry, pediatric ophthalmology, pediatric otolaryngology, pediatric pulmonology, pediatric radiology, pediatric rehabilitation, pediatric sports medicine, pediatric surgery, pediatric residency and med/peds residency.

Evolution Of Occupational Therapy Practice: Life History Of Dr. Julie Grabanski, Phd, Otr/L, Sydney Gayton, Madisyn Rick

Oral History Student Papers

This qualitative study was completed in order to gather information about the history of the occupational therapy practice. The process was guided by the Kawa Model and life histories of influencers in North Dakota and Wyoming were collected. A face-to-face interview was conducted at the University of North Dakota with Dr. Julie Grabanski in order to collect this needed information. After the transcription and data analysis were complete, the student researchers discovered that Dr. Julie Grabanski has applied what she has learned from her occupational therapy education to her everyday life. It was also found that she embraces an occupational …

Autoethnography Of A Whitegirl Marriage And Family Therapist's Experience Working On The Rez, Andrea L. Cuva

Department of Family Therapy Dissertations and Applied Clinical Projects

Despite the abundance of literature regarding potentially effective treatment modalities for Native American clients, researchers have been unable to identify an empirically proven effective treatment modality for this population. Common recommendations/considerations for therapists working with Native clients have been identified throughout literature; however, such findings were gathered by insiders (i.e., Native researchers or trained Tribal staff), which has left questions regarding the efficacy of such recommendations when applied by non-Native therapists. Due to Native American history, elaborate IRB requirements were put in place to ensure ethical research with this population but impedes the research process. I conducted an analytic autoethnography …

Combined Impairments In Vision, Hearing And Cognition Are Associated With Greater Levels Of Functional And Communication Difficulties Than Cognitive Impairment Alone: Analysis Of Interrai Data For Home Care And Long-Term Care Recipients In Ontario, Dawn M. Guthrie, Jacob G.S. Davidson, Nicole Williams, Jennifer Campos, Kathleen Hunter, Paul Mick, Joseph B. Orange, M. Kathleen Pichora-Fuller, Natalie A. Phillips, Marie Y. Savundranayagam, Walter Wittich

Health Sciences Faculty Publications

Objectives: The objective of the current study was to understand the added effects of having a sensory impairment (vision and/or hearing impairment) in combination with cognitive impairment with respect to health-related outcomes among older adults (65+ years old) receiving home care or residing in a long-term care (LTC) facility in Ontario, Canada.

Methods: Cross-sectional analyses were conducted using existing data collected with one of two interRAI assessments, one for home care (n = 291,824) and one for LTC (n = 110,578). Items in the assessments were used to identify clients with single sensory impairments (e.g., vision only [VI], hearing only …

Empowering Medicine, The 2018 Annual Report Of The Jackson Laboratory, The Jackson Laboratory

Annual Reports

The 2018 Annual Report from The Jackson Laboratory (JAX), which highlights some of the major events and accomplishments of the year.

Intermediate-Risk Meningioma: Initial Outcomes From Nrg Oncology Rtog 0539, L. Rogers, P. Zhang, M. A. Vogelbaum, A. Perry, L. S. Ashby, J. M. Modi, A. M. Alleman, J. Galvin, J. P. S. Knisely, M. P. Mehta, +5 Additional Authors

Journal Articles

No abstract provided.

Medical Literary Messenger (Vol. 6, No. 1, Fall/Winter 2018)

Medical Literary Messenger

Lucky / Erika Walker -- What I Fear / Kathleen Walsh Spencer -- Swimming Alone / Charles Grosel -- This Is What We Had / Marissa S. McNamara -- Study of Skull / Annalyn Welp -- Origin of an Epidemic / John Graham-Pole -- Shedding Light / Sharon Fain -- Beam of Healing: The Trigeminal Neuralgia Series / Douglas W. Johnson -- First Shower / Tracy Rothschild Lynch -- Death Sentence / Barry Peters -- The Diagnosis / Roger Hart -- Drive By / Tony Reevy -- Heart (Ink), 2017 / Laurie Wacks -- Brain (Ink), 2015 / Laurie Wacks …

Identifying Medication Management Smartphone App Features Suitable For Young Adults With Developmental Disabilities: Delphi Consensus Study, Teresa M. Salgado, Alexa Fedrigon, Donna Riccio Omichinski, Michelle A. Meade, Karen B. Farris

Pharmacotherapy and Outcomes Science Publications

Background: Smartphone apps can be a tool to facilitate independent medication management among persons with developmental disabilities. At present, multiple medication management apps exist in the market, but only 1 has been specifically designed for persons with developmental disabilities. Before initiating further app development targeting this population, input from stakeholders including persons with developmental disabilities, caregivers, and professionals regarding the most preferred features should be obtained.

Objective: The aim of this study was to identify medication management app features that are suitable to promote independence in the medication management process by young adults with developmental disabilities using a Delphi consensus …

Variability In Antifungal Utilization Among Neonatal, Pediatric, And Adult Inpatients In Academic Medical Centers Throughout The United States Of America, Jeremy S. Stultz, Rose Kohinke, Amy L. Pakyz

Pharmacotherapy and Outcomes Science Publications

Background
Identification of factors associated with antifungal utilization in neonatal, pediatric, and adult patient groups is needed to guide antifungal stewardship initiatives in academic medical centers.

Methods
For this hospital-level analysis, we analyzed antifungal use in hospitals across the United States of America, excluding centers only providing care for hematology/oncology patients. Analysis of variance was used to compare antifungal use between patient groups. Three multivariable linear regression models were used to determine independent factors associated with antifungal use in the neonatal, pediatric, and adult patient groups.

Results
For the neonatal, pediatric, and adult patient groups, 54, 44, and 60 hospitals …

The Humanistic And Economic Burden Associated With Anxiety And Depression Among Adults With Comorbid Diabetes And Hypertension, Kimberly Wallace, Xiaohui Zhao, Ranjita Misra, Usha Sambamoorthi

Faculty & Staff Scholarship

We conducted a retrospective cross-sectional study to estimate the humanistic and economic burden associated with depression and anxiety among adults with comorbid diabetes and hypertension. Pooled data from the 2013 and 2015 Medical Expenditure Panel Survey were used to include adults (≥18 years old) who were alive and diagnosed with both diabetes and hypertension during the observation period. We assessed the humanistic burden with health-related quality of life (HRQoL) and economic burden with the total annual healthcare expenditures. Depending on the presence/absence of depression and anxiety, the study sample was divided into four groups (i.e., no depression/anxiety, depression only, anxiety …

Corrected And Republished From: The Cop9 Signalosome Interacts With And Regulates Interferon Regulatory Factor 5 Protein Stability., J. Korczeniewska, B. J. Barnes

Journal Articles

© 2018 American Society for Microbiology. The transcription factor interferon regulatory factor 5 (IRF5) exerts crucial functions in the regulation of host immunity against extracellular pathogens, DNA damage-induced apoptosis, death receptor signaling, and macrophage polarization. Tight regulation of IRF5 is thus warranted for an efficient response to extracellular stressors and for limiting autoimmune and inflammatory responses. Here we report that the COP9 signalosome (CSN), a general modulator of diverse cellular and developmental processes, associates constitutively with IRF5 and promotes its protein stability. The constitutive CSN/IRF5 interaction was identified using proteomics and confirmed by endogenous immunoprecipitations. The CSN/IRF5 interaction occurred on …

Lupus Community Panel Proposals For Optimising Clinical Trials: 2018, J. T. Merrill, S. Manzi, C. Aranow, A. Askenase, I. Bruce, E. Chakravarty, B. Chong, K. Costenbader, M. Dall'era, V. P. Werth, +7 Additional Authors

Journal Articles

© 2018 Article author(s). Formidable impediments stand in the way of treatment development for lupus. These include the unwieldy size of current trials, international competition for scarce patients, complex outcome measures and a poor understanding of these outcomes in the world at large. The heterogeneity of the disease itself coupled to superimposition of variegated background polypharmacy has created enough immunological noise to virtually ensure the failure of lupus treatment trials, leaving an understandable suspicion that at least some of the results in testing failed drugs over the years may not have been negative, but merely uninterpretable. The authors have consulted …

Insulin-Like Growth Factor 2: A Poor Prognostic Biomarker Linked To Racial Disparity In Women With Uterine Carcinosarcoma, A. R. Van Arsdale, R. C. Arend, M. J. Cossio, B. K. Erickson, Y. Wang, D. W. Doo, C. A. Leath, G. L. Goldberg, G. S. Huang

Journal Articles

© 2018 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. The objective of this study was to investigate the relationship of insulin-like growth factor 2 (IGF2) expression and survival in women with uterine carcinosarcoma (UCS). Insulin-like growth factor 2 protein expression was determined by immunohistochemical staining of tumor tissues from 103 patients with UCS. The H-score (product of staining intensity and percentage positive cells) was quantified for the epithelial cytoplasmic (EC), epithelial nuclear (EN), and malignant stromal compartments. Multivariable Cox proportional hazard regression models were used to examine the relationship of IGF2 levels with progression-free survival (PFS) …

Implementation And Utilization Of Hypofractionation For Breast Cancer, P. Gilbo, L. Potters, L. Lee

Journal Articles

© 2018 The Authors Purpose: Hypofractionation (HF) of whole breast irradiation has become a standard treatment regimen because randomized trials continue to demonstrate equivalence in survival and local control compared with conventional fractionation. In 2011, the American Society for Radiation Oncology (ASTRO) adopted clinical guidelines on the proper selection of HF. Nevertheless, utilization remains lower than predicted. We evaluate the effects of clinical directives that serve as default treatment decisions and prospective contouring rounds on the implementation of HF in a large, multicenter radiation oncology department. Methods and materials: In 2010, we implemented consensus-driven and evidence-based clinical directives to guide …

Evaluation Of Prothrombin Complex Concentrate Use In A Community Health System, Corissa L. Piatka Pharmd, Tim Johnston Pharmd, Bcps, Bcccp, Jim Roy Pharmd, Bcps, Bcccp

Parkview Pharmacy Department

Poster Presentation

2018 ASHP Midyear Clinical Meeting / Anaheim, California / Poster # 11-310

Objective: Evaluate by indication the appropriateness of prothrombin complex concentrate (PCC) use in a community health system.

Implementation Of A Pharmacist-Guided Procalcitonin Protocol In A Community Hospital, Jasmine Coatie Pharmd

Pharmacy Residency

Presentation given at Great Lakes Pharmacy Residency Conference 2018

January 2018, New England Osteopathic Heritage Center

New England Osteopathic Heritage Center Newsletter

New England Osteopathic Heritage Center's annual newsletter for January 2018

New Ways Of Predicting Efficacy Of Antidepressants, Kayla Ternes

Physician Assistant Scholarly Project Papers

Major depressive disorder (MDD) is a neuropsychiatric condition that is becoming increasingly prevalent in our country. According to Cai, Huang, and Hao (2015), MDD is “common and devastating” (p. 61) and has a very complex pathophysiology. Until recently, a definitive etiology had not been found, however, new evidence has suggested that Brain-derived neurotrophic factor (BDNF) and cognitive-emotional biomarkers may be a key into the mechanism of this disorder.

My literature review of articles found in PubMed, CINAHL, Cochrane Library, and PsychINFO within the last ten years focused on the hypotheses of the pathophysiology of MDD, cognitive-emotional biomarkers, and BDNF. The …

Menstrual Cycle And The Temporal Discrimination Threshold, Eavan M. Mc Govern, Emer O'Connor, Ines Beiser, Laura Williams, John Butler, Brendan Quinlivan, Shruti Narasimham, Rebecca Beck, Richard B. Reilly, Sean O'Riordan, Michael Hutchinson

Articles

The temporal discrimination threshold (TDT) is a proposed pre-clinical biomarker (endophenotype) for adult onset isolated focal dystonia (AOIFD). Age- and sex-related effects on temporal discrimination demonstrate that women, before the age of 40 years, have faster temporal discrimination than men but their TDTs worsen with age at almost three times the rate of men. Thus after 40 years the TDT in women is progressively worse than in men. AOIFD is an increasingly female-predominant disorder after the age of 40; it is not clear whether this age-related sexually-dimorphic difference observed for both the TDT and sex ratio at disease onset in …

Influence Of Team Rating On Running Performance In Elite Gaelic Football, Shane Mangan, Shane Malone, Martin Ryan, Jason Mcgahan, Joe Warne, Denise Martin, Cian O'Neill, Con Burns, Kieran Collins

Articles

It is currently unknown how team rating influences running performance in Gaelic football. Global positioning system technologies were used to quantify match-running performance within 5 elite Gaelic football teams over a period of 5 years (2012-2016). In total 780 player data sets were collected over 95 matches. Running performance variables included total distance, high-speed distance (≥17 km·h), and the percentage of high-speed distance. Team ratings were determined objectively using the Elo rating system for Gaelic football. Reference team rating had trivial effects on total distance (p = 0.011, partial η = 0.008) and high-speed distance (p = 0.011, partial η …

National Children’S Dental Health Month - Creating Your Own Press Release (2018), American Dental Association Foundation

National Children's Dental Health Month

No abstract provided.

National Children’S Dental Health Month - Program Planning Guide (2018), American Dental Association Foundation

National Children's Dental Health Month

No abstract provided.

National Children's Dental Health Month Activity Book (2018), American Dental Association Foundation

National Children's Dental Health Month

No abstract provided.

Developing Racial Literacy And Cultural Fluency In The Pediatric Healthcare Setting: The Use Of Staff Focus Groups To Address Implicit Bias And Cultural Competence When Working With A Culturally Diverse Patient Population, Natalie Kinsky

Graduate Student Independent Studies

Developing Racial Literacy and Cultural Fluency in the Pediatric Healthcare Setting: The use of staff focus groups to address implicit bias and cultural competence when working with a culturally diverse patient population by Natalie Kinsky.

The purpose of this evidence-based practice (EBP), quality improvement project was to explore how targeted education and discussion, delivered through healthcare staff focus groups pertaining to race, culture, and bias, affect staff members’ knowledge and awareness of how these issues and experiences affect pediatric patients/families.

The EBP project consisted of pediatric healthcare staff focus groups to discuss topics of race, bias, and culture. The self-selected …

Ten Years Of Food Policy Governance In New York City: Lessons For The Next Decade, Nicholas Freudenberg, Nevin Cohen, Janet Poppendieck, Craig Willingham

Publications and Research

No abstract provided.