Medicine and Health Sciences Commons^™

Reliability And Concurrent Validity Of An Alternative Method Of Lateral Lumbar Range Of Motion In Athletes, Mark D. Hecimovich, Jeffrey J. Herbert

Faculty Publications

Background: Cricket bowling involves combined spinal movements of side bending and rotation and, consequently, injury to the low back is a common problem. Therefore the assessment of lumbar spine kinematics has become a routine component in preseason screening. This includes static measurement of lateral spinal flexion as asymmetrical range of motion may predispose an athlete to low back injury.

Objectives: This study examined intra-rater reliability and concurrent validity of the fingertip-to-floor distance test (FFD) when compared to a criterion range of motion measure.

Methods: Thirty-four junior-level cricket players aged 13‑16 years were recruited. Lumbar spine lateral flexion …

Investigating Disparities In Behavior And Care Between Alaska Native And Non-Hispanic White Victims Of Sexual Violence: The Importance Of Culturally Competent Nursing Care, Danielle Koster

Inquiry: The University of Arkansas Undergraduate Research Journal

The purpose of this research was to determine the existence of health care disparities experienced by Alaska Native women victims of sexual violence and to address the need for sexual assault nurse examiners (SANEs) to provide culturally competent care. This was a secondary data analysis of research collected from over 1,600 Alaska SANE surveys between 1996-2006. Variables investigated included: behaviors during examination, condition during assault, time from assault to report, hospital admittance, injuries sustained, and victim-suspect relationships. Alaska Native women were described as having less controlled behavior, being less cooperative, and less likely to be sober; they also often suffered …

Ready, Set, Network! Research Speed Networking For Clinicians, Scientists And Engineers, Pamela M. Dillon, Karen H. Gau

VCU Libraries Faculty and Staff Presentations

Objectives: A 2013 Institute of Medicine report urged researchers to “engage in additional substantive and productive collaborations” to address important clinical/translational science questions. To encourage team science among our researchers, Tompkins-McCaw Library for the Health Sciences and Center for Clinical and Translational Research hosted a speed networking event, specifically targeting engineers, clinicians, and basic scientists; an analysis of the event is below.

Methods: Invitations were distributed to clinicians, engineers, and basic scientists. To maximize interactions without increasing time spent at the event, researchers were divided into three groups. The event was planned such that each group would meet everyone from …

Baystate Medical Center Nursing Report - 2016, Christine Klucznik Dnp, Rn

Baystate Medical Center Nursing Report

No abstract provided.

Examining The Impact Of Accreditation On A Primary Healthcare Organization In Qatar, Alia G. Banna

2010-2016 Archived Posters

While a modest body of literature exists on accreditation, little research has been conducted on the impact of accreditation on primary care in the Middle East. This descriptive correlational study assessed the changes resulting from the integration of Accreditation Canada International’s (ACI) program at Primary Health Care Corporation (PHCC) in the State of Qatar.

Maternal And Child Health Access Disparities Among Recent African Immigrants In The United States, Bakali Mukasa

2010-2016 Archived Posters

Health care disparities and U.S. national public health concerns and disproportionately affect minority populations. Analysis of published studies on the health of larger immigrant populations from Europe, Asia, South American, and the Caribbean revealed a knowledge gap on the health of African and other minority immigrants. This phenomenological study of 11 recent African immigrants concerned access to maternal and child health (MCH) care as well as the causes and effects of disparities to care-seeking experiences. The results may support interventions to improve health care access and health outcomes of minority immigrants in the United States and beyond.

Mental Health Service Use Among Older African Americans And Caribbean Blacks Who Experience Traumatic Events, Camille Huggins

2010-2016 Archived Posters

This study identifies factors associated with mental health service use among older African American and Caribbean Blacks who have experienced a traumatic event. Method: Data drawn from the Research on Depression and Anxiety Disorders in Elders Clinical Correlation project (RDADE). Hierarchical logistic regressions were used to compute odds ratio. Result: Age, gender, spirituality, depression and access to medical insurance determines the utilization of mental health services. Implications for depression screening in this population.

The Association Between Osteoporosis And Early Menopause Following Hysterectomy, Mia Meeyaong-Won Botkin

2010-2016 Archived Posters

This study is to examine the association between osteoporosis and demographic and behavioral factors in women of age 50 and older who had undergone hysterectomies prior to reaching natural menopause. The 2009-2010 National Health and Nutrition Examination Survey (NHANES) was analyzed using multiple logistic regressions analysis. Osteoporosis was inversely associated with demographic and behavioral factors. Non-Hispanic Whites of the age of 36-45 at the time of the hysterectomies were significantly associated with osteoporosis. This study may drive positive social change by facilitating public health to promote and implement effective behavioral interventions in women.

National Children's Dental Health Month Activity Book (2016), American Dental Association Foundation

National Children's Dental Health Month

No abstract provided.

Open Access Papers Have A Greater Citation Advantage In The Author-Pays Model Compared To Toll Access Papers In Springer And Elsevier Open Access Journals, Elaine Sullo

Himmelfarb Library Faculty Publications

No abstract provided.

Micrornas Are Involved In The Development Of Morphine-Induced Analgesic Tolerance And Regulate Functionally Relevant Changes In Serpini1., Jenica D. Tapocik, Kristin Ceniccola, Cheryl L. Mayo, Melanie L. Schwandt, Matthew Solomon, Bi-Dar Wang, Truong V. Luu, Jacqueline Olender, Thomas Harrigan, Thomas M. Maynard, Greg I. Elmer, Norman H. Lee

Pharmacology and Physiology Faculty Publications

Long-term opioid treatment results in reduced therapeutic efficacy and in turn leads to an increase in the dose required to produce equivalent pain relief and alleviate break-through or insurmountable pain. Altered gene expression is a likely means for inducing long-term neuroadaptations responsible for tolerance. Studies conducted by our laboratory (Tapocik et al., 2009) revealed a network of gene expression changes occurring in canonical pathways involved in neuroplasticity, and uncovered miRNA processing as a potential mechanism. In particular, the mRNA coding the protein responsible for processing miRNAs, Dicer1, was positively correlated with the development of analgesic tolerance. The …

Legal Space For Syringe Exchange Programs In Hot Spots Of Injection Drug Use-Related Crime., Sean T. Allen, Monica Ruiz, Monique Turner, Jeff Jones

Prevention and Community Health Faculty Publications

BACKGROUND: Copious evidence indicates that syringe exchange programs (SEPs) are effective structural interventions for HIV prevention among persons who inject drugs (PWID). The efficacy of SEPs in supporting the public health needs of PWID populations is partially dependent on their accessibility and consistent utilization among injectors. Research has shown that SEP access is an important predictor of PWID retention at SEPs, yet policies exist that may limit the geographic areas where SEP operations may legally occur. Since 2000 in the District of Columbia (DC), SEP operations have been subject to the 1000 Foot Rule (§48-1121), a policy that prohibits the …

Importance Of Hereditary And Selected Environmental Risk Factors In The Etiology Of Inflammatory Breast Cancer: A Case-Comparison Study., Roxana Moslehi, Elizabeth Freedman, Nur Zeinomar, Carmela Veneroso, Paul H. Levine

Epidemiology Faculty Publications

BACKGROUND: To assess the importance of heredity in the etiology of inflammatory breast cancer (IBC), we compared IBC patients to several carefully chosen comparison groups with respect to the prevalence of first-degree family history of breast cancer.

METHODS: IBC cases (n = 141) were compared to non-inflammatory breast cancer cases (n = 178) ascertained through George Washington University (GWU) with respect to the prevalence of first-degree family history of breast cancer and selected environmental/lifestyle risk factors for breast cancer. Similar comparisons were conducted with subjects from three case-control studies: breast cancer cases (n = 1145) and unaffected controls (n = …

Coronary Flow Reserve In Adults With Systemic Right Or Single Ventricles, Laura J. Olivieri, Li-Yueh Hsu, Anitha S. John, Karen S. Kuehl, Andrew Arai

Pediatrics Posters and Presentations

No abstract provided.

Hormonal Responses To Non-Nutritive Sweeteners In Water And Diet Soda., Allison C. Sylvetsky, Rebecca J Brown, Jenny E Blau, Mary Walter, Kristina I Rother

Exercise and Nutrition Sciences Faculty Publications

BACKGROUND: Non-nutritive sweeteners (NNS), especially in form of diet soda, have been linked to metabolic derangements (e.g. obesity and diabetes) in epidemiologic studies. We aimed to test acute metabolic effects of NNS in isolation (water or seltzer) and in diet sodas.

METHODS: We conducted a four-period, cross-over study at the National Institutes of Health Clinical Center (Bethesda, Maryland). Thirty healthy adults consumed 355 mL water with 0 mg, 68 mg, 170 mg, and 250 mg sucralose, and 31 individuals consumed 355 mL caffeine-free Diet Rite Cola™, Diet Mountain Dew™ (18 mg sucralose, 18 mg acesulfame-potassium, 57 mg aspartame), and seltzer …

Vancouver, Wa: Strengthening Neighborhoods Through Student Resilience, Center For Health And Health Care In Schools

Center for Health and Health Care in Schools

No abstract provided.

Complete Genome Sequence Of A Ctx-M-15-Producing Escherichia Coli Strain From The H30rx Subclone Of Sequence Type 131 From A Patient With Recurrent Urinary Tract Infections, Closely Related To A Lethal Urosepsis Isolate From The Patient's Sister., Timothy J. Johnson, Maliha Aziz, Cindy M. Liu, Evgeni Sokurenko, Dagmara I. Kisiela, Sandip Paul, Paal S. Andersen, James R. Johnson, Lance B. Price

Environmental and Occupational Health Faculty Publications

We report here the complete genome sequence, including five plasmid sequences, of Escherichia coli sequence type 131 (ST131) strain JJ1887. The strain was isolated in 2007 in the United States from a patient with recurrent cystitis, whose caregiver sister died from urosepsis caused by a nearly identical strain.

Don't Ask For Fair Treatment? A Gender Analysis Of Ethnic Discrimination, Response To Discrimination, And Self-Rated Health Among Marriage Migrants In South Korea., Yugyun Kim, Inseo Son, Dainn Wie, Carles Muntaner, Hyunwoo Kim, Seung-Sup Kim

Environmental and Occupational Health Faculty Publications

BACKGROUND: Ethnic discrimination is increasingly common nowadays in South Korea with the influx of migrants. Despite the growing body of evidences suggests that ethnic discrimination negatively impacts health, only few researches have been conducted on the association between ethnic discrimination and health outcomes among marriage migrants in Korea. This study sought to examine how ethnic discrimination and response to the discrimination are related to self-rated health and whether the association differs by victim's gender.

METHODS: We conducted two-step analysis using cross-sectional dataset from the 'National Survey of Multicultural Families 2012'. First, we examined the association between perceived ethnic discrimination and …

No Good Deed Goes Unpunished, Kylie C. Smith

Ethics and Social Justice Center Essay Prizes

Healthcare professionals have a moral obligation to provide pro bono services in order to meet the health needs of their community. However, there are several obstacles and factors that make implementing pro bono practices very difficult. The purpose of this essay was to discuss both the pros and cons of providing pro bono health care services as a means of bridging the gap of health disparities in society.

Acceptability Study On Hiv Self-Testing Among Transgender Women, Men Who Have Sex With Men, And Female Entertainment Workers In Cambodia: A Qualitative Analysis, Khuondyla Pal, Chanrith Ngin, Sovannary Tuot, Pheak Chhoun, Cheaty Ly, Srean Chhim, Siyan Yi

Background: In Cambodia, HIV prevalence is high while HIV testing rates remain low among transgender women (TG women), men who have sex with men (MSM), and female entertainment workers (FEW). Introducing self-testing for HIV to these key populations (KPs) could potentially overcome the under-diagnosis of HIV and significantly increase testing rates and receipt of the results, and thus could decrease transmission. Therefore, this study aimed to determine the acceptability of HIV self-testing (HIVST) among these three categories of KPs.

Methods: This study was conducted through focus group discussions (FGDs) with TG women, MSM, and FEW in Phnom Penh …

First-Episode Of Synthetic Cannabinoid-Induced Psychosis In A Young Adult, Successfully Managed With Hospitalization And Risperidone, Aaron Roberto, Aileen Lorenzo, Jonathan Young, Abhishek Mohan, Subhash Pinnaka, Kyle Lapidus

NYMC Residents/Fellows Publications

Synthetic cannabinoids- (SCs-) induced psychosis is a growing public health concern. It leads to significant impairment, including emotional distress, difficulty communicating, and other debilitating symptoms. In this case report, we discuss a patient with no previous history of psychotic symptoms, presenting with first-episode psychosis in the context of progressive, acutely worsening, disorganized, psychotic thoughts and behaviors following prolonged use of SCs. We also discuss relevant literature on SCs-induced psychosis, highlighting its prevalence, presentation, diagnosis, and recommended management. It is important to diagnose and treat SCs-induced psychosis as early and efficiently as possible, in order to alleviate symptoms while limiting functional …

Active Stiffening Of F-Actin Network Dominated By Structural Transition Of Actin Filaments Into Bundles, Shengmao Lin, Xinwei Han, Gary C.P. Tsui, David Hui, Linxia Gu

Department of Mechanical and Materials Engineering: Faculty Publications

Molecular motor regulated active contractile force is key for cells sensing and responding to their mechanical environment, which leads to characteristic structures and functions of cells. The F-actin network demonstrates a two-order of magnitude increase in its modulus due to contractility; however, the mechanism for this active stiffening remains unclear. Two widely acknowledged hypotheses are that active stiffening of F-actin network is caused by (1) the nonlinear force-extension behavior of cross-linkers, and (2) the loading mode being switched from bending to stretching dominated regime. Direct evidence supporting either theory is lacking. Here we examined these hypotheses and showed that a …

Novel Role Of Cd47 In Obesity-Associated Metabolic Dysfunctions, Heather L. Norman-Burgdolf

Theses and Dissertations--Pharmacology and Nutritional Sciences

Obesity and its associated comorbidities are of global concern. These complications are largely driven by perturbations in energy homeostasis, inflammation, and oxidative stress within metabolic tissues. Although these underlying pathways have been established, molecular mechanisms augmenting metabolic dysfunction have not been fully defined. CD47, a ubiquitously expressed cell membrane receptor, has been previously implicated in the development of inflammation and oxidative stress in a number of disease conditions. Previous work from our lab and others has confirmed that the most potent ligand of CD47, TSP1, plays a critical role in facilitating inflammation and metabolic dysfunction in diet-induced obesity. Whether these …

Alterations In Plasma Protein C Activity Levels Following Apheresis Platelet Donation And Whole Blood Donation, Frances Duggan, Kathleen O'Sullivan, Joan P. Power, Michael Healy, William G. Murphy

Department of Biological Sciences Publications

Citrate toxicity from platelet apheresis donation has been extensively reported. Effects include symptomatic adverse reactions, silent prolongation of QTc interval on an electrocardiogram and long-term bone effects. While haemostatic impairment is not of concern in healthy plateletpheresis donors, these donors receive doses of citrate during the procedures that induce significant in vivo anticoagulation. We wished to measure the effects this process has on other markers of haemostatic homeostasis, and, in particular, on protein C activity levels. Protein C binds to its activation complex through divalent cation bridges, and is, therefore, susceptible to inactivation by citrate: an effect on protein C …

The Experiences Of The Parents Of Children Undergoing Occupational Therapy Intervention For The Occupation Of Feeding, Michael A. Coldiron

Occupational Therapy Doctorate Capstone Projects

Occupational therapy practitioners practice under the values of client-centered care and cultural sensitivity. This valuates the role of the occupational therapy practitioner in pediatric feeding intervention pertaining to diverse diets. The problem is that there is a lack of research into the experiences of individuals who consume a diverse diet as they undergo occupational therapy intervention for the occupations of feeding and eating. The purpose of this study was to enable individuals with diverse diets to self-report these experiences. Participants were questioned on the challenges they encountered and detailed questions regarding the types of experiences they face. The study was …

Impact Of An Occupation-Based Practice (Obp) Learning Module On Perceptions Of Obp And Selection Of Occupation-Based Interventions By Occupational Therapy Assistant Students, Allen S. Keener

Occupational Therapy Doctorate Capstone Projects

The purpose of this Capstone project was to immerse OTA students in classroom experiences designed to increase their knowledge of key concepts of occupation, OBP, and ability to select occupation-based interventions. The hypothesis of the researcher was that engagement in the module would create an increase in OTA student knowledge in the areas of occupation and OBP, as well as the ability to select occupation-based interventions based on client scenarios.

Prior to engagement in module class sessions, students engaged in pretesting activities, consisting of demographic information, a short essay, and an intervention selection task. Once completed, students participated in a …

Association Of Blood Lead Levels In Children 0-72 Months With Living In Mid-Appalachia: A Semiecologic Study, R. Constance Wiener, R. J. Jurevic

Faculty & Staff Scholarship

Introduction—Lead exposure in children remains a significant public health issue, although many advances have been made. The Mid-Appalachia area (Kentucky, New York, Ohio, Pennsylvania, and West Virginia) is 89–91% rural with a population density of 16–21 people/km2 (41–54 people/mi2 ). Mid-Appalachia has significant health disparities including concerns for the consequences of greater lead exposure to children due to mining and industrial footprints, and existing older housing. The purpose of this study is to compare the reported blood lead levels of screened children, aged 0–72 months in Mid-Appalachia, to the children in the USA in general.

Methods—Data from the Centers for …

Sexual Minority (Lgbtq) Youth And Role Of Health Care Provider, Mandakini Sadhir, Stephanie J. Stockburger, Hatim A. Omar

Pediatrics Faculty Publications

Adolescence is a time period of physical, psychological and cognitive changes. It is an important phase for an individual to discover who they really are (self-identity), how they are perceived (social identity) and how they fit into the environment they live in.¹ One of the major tasks of adolescence is sexual maturation and sexual and /or gender identity development.² Adolescents who are developing as gay, lesbian, bisexual or transgender face a tremendous challenge of establishing their identity which is often complex.³ They cope with the feelings of being different and are in constant dilemmas about revealing their …

Screening Of Exosomal Micrornas From Colorectal Cancer Cells, Cillian Clancy, Sonja Khan, Claire L. Glynn, Emma Holian, Peter Dockery, Pierce Lalor, James A.L. Brown, Myles Joyce, Michael J. Kerin, Roisin M. Dwyer

Forensic Science Publications

BACKGROUND: Cells release extracellular membrane vesicles including microvesicles known as exosomes. Exosomes contain microRNAs (miRNAs) however the full range within colorectal cancer cell secreted exosomes is unknown. OBJECTIVE: To identify the full range of exosome encapsulated miRNAs secreted from 2 colorectal cancer cell lines and to investigate engineering of exosomes over-expressing miRNAs. METHODS: Exosomes were isolated from HCT-116 and HT-29 cell lines. RNA was extracted from exosomes and microRNA array performed. Cells were engineered to express miR-379 (HCT-116-379) or a non-targeting control (HCT-116-NTC) and functional effects were determined. Exosomes secreted by engineered cells were transferred to recipient cells and the …

Preserving Function In Individuals With Parkinson's Disease, Thu Anh Lenguyen

MOT Student Capstones

Incidence of Parkinson's disease is growing due to the rise of the aging population requiring increased need for occupational therapy to facilitate independence and aging in place. Occupational therapy practitioners will need to have a general understanding of how to treat clients with the disease by becoming informed on the impact on occupations, evidence-based interventions, and available resources to clients and caregivers. Objectives of this project related to facilitating aging in place by maximizing client's quality of life and independence in their least restrictive environment. Three objectives were the focus of this project: • Occupational therapy practitioners will gain a …