Medicine and Health Sciences Commons^™

Time Of Year Affects Surgical Outcome Of Pediatric Congenital Heart Disease, Krystin Sinclair

Honors Projects in Science and Technology

Approximately 35,000 children are born in the US each year with Congenital Heart Disease (CHD). Surgical timing for many of these conditions is elective, and the distribution of surgical cases, therefore, varies with time of year. The hypothesis of this project is that time of the year for surgery is associated with mortality, length of hospital stay (LOS), and total hospital costs. A retrospective, cohort study was performed, using the Pediatric Health Information Systems (PHIS) Database to investigate these relationships.

Parental Predictors Of Adolescent Alcohol Use And Alcohol-Related Consequences, Robin Hausheer, Diana M. Doumas, Susan Esp, Courtney Cuffee

Counselor Education Faculty Publications and Presentations

This study examined parental factors as predictors of alcohol use and alcohol-related consequences among 9^th grade students (N = 296). Perception of parental disapproval of teen drinking and perceived quality of parent-child general communication were significant predictors of adolescent alcohol use and alcohol-related consequences. Implications for parent education are discussed.

Nurses’ Perceptions Of Parents Staying During Chronically Ill Child’S Hospitalization: Learning To Speak The Same Language, Nicole Toscano

Social Work Theses

Since parents and nurses are at the forefront of a hospitalized child’s care, it is crucial to understand the views of parents and nurses to provide the best care for the patient. Parental views have been examined by previous research; thus, this qualitative research study assesses nurses’ perceptions concerning the parental role during a child’s hospitalization. Assessing where nurses’ place parents in the medical world will help the overall care of the patient. The results of the semi-structured interviews of two nurses corresponds with the hypothesis that nurses’ view parents as integral to the care of the patient, even if …

Equine Arteritis Virus Uses Equine Cxcl16 As An Entry Receptor, Sanjay Sarkar, Lakshman Chelvarajan, Yun Young Go, Frank Cook, Sergey Artiushin, Shankar Mondal, Kelsi Anderson, John E. Eberth, Peter J. Timoney, Theodore S. Kalbfleisch, Ernest F. Bailey, Udeni B. R. Balasuriya

Veterinary Science Faculty Publications

Previous studies in our laboratory have identified equine CXCL16 (EqCXCL16) to be a candidate molecule and possible cell entry receptor for equine arteritis virus (EAV). In horses, the CXCL16 gene is located on equine chromosome 11 (ECA11) and encodes a glycosylated, type I transmembrane protein with 247 amino acids. Stable transfection of HEK-293T cells with plasmid DNA carrying EqCXCL16 (HEK-EqCXCL16 cells) increased the proportion of the cell population permissive to EAV infection from < 3% to almost 100%. The increase in permissiveness was blocked either by transfection of HEK-EqCXCL16 cells with small interfering RNAs (siRNAs) directed against EqCXCL16 or by pretreatment with guinea pig polyclonal antibody against EqCXCL16 protein (Gp anti-EqCXCL16 pAb). Furthermore, using a virus overlay protein-binding assay (VOPBA) in combination with far-Western blotting, gradient-purified EAV particles were shown to bind directly to the EqCXCL16 protein in vitro. The binding of biotinylated virulent EAV strain Bucyrus at 4°C was significantly higher in HEK-EqCXCL16 cells than nontransfected HEK-293T cells. Finally, the results demonstrated …

Building Expert Consensus On Including Indicators Of Moisture Associated Skin Damage In The National Database Of Nursing Quality Indicators (Ndnqi), Mary Caroleen Arnold Long

Capstone Projects

Pressure ulcer (PU) data are collected by hospitals and reported quarterly as a nursing sensitive quality indicator via the National Database of Nursing Quality Indicators (NDNQI). Incontinence-associated dermatitis (IAD) and gluteal intertriginous dermatitis (ITD), both forms of moisture associated skin damage (MASD), are caused by moisture, not pressure or shear. These two forms of skin damage may be mistaken for PUs and may be reported in error as PUs. If the assessment of the skin damage is incorrect, the reporting is incorrect and the NDNQI database is incorrect. If the NDNQI database is incorrect then practice and policy regarding identification, …

Sex, Milk, And Cookies: Tackling Sexual Health Promotion On A Catholic College Campus, Mary Franz

All College Thesis Program, 2016-2019

A great divide exists among parents, policy makers, educational institutions, and the public at large regarding how to prevent the negative consequences of sexual activity among young adults. Some educators believe that sex education programs should promote abstinence as the best behavioral goal for students; however, a more intense debate surrounds whether this should be the only message that adolescents receive about sex or just one element of a more comprehensive view of sexuality and informed sex choices. Catholic colleges face a particularly difficult challenge in deciding what information to provide to students and more significantly, which topics to avoid …

Women-Only Workout Hours, Kay Mackinnon

Research Methods - Posters

This study explores female students’ preferences for a women-only section or hours at Eastern Illinois University (EIU) Student Recreation Center (SRC)

Adverse Childhood Experiences In Rural And Urban Contexts, Jean A. Talbot Phd, Donald Szlosek Mph, Erika C. Ziller Phd

Mental Health / Substance Use Disorders

Recent research shows that rural children are more likely than urban children to experience certain kinds of adversity. Researchers at the Maine Rural Health Research Center looked at how adverse childhood experiences (ACEs) have affected rural and urban adults. Using data from the Behavioral Risk Factor Surveillance System Assessment, this study found that, while the prevalence of ACEs was comparable in rural and urban adults, over half of rural adults surveyed reported having ACE exposure.Among those with any ACE history, about one quarter experienced four or more ACEs. Policy implications and strategies are highlighted in this brief.

Key Findings:

• Past …

A Subset Of Latency-Reversing Agents Expose Hiv-Infected Resting Cd4+ T-Cells To Recognition By Cytotoxic T-Lymphocytes., R. Brad Jones, Stefanie Mueller, Rachel O'Connor, Katherine Rimpel, Derek D Sloan, Allison S. Thomas, Sara Karandish, Szu-Han Huang, +13 More

Microbiology, Immunology, and Tropical Medicine Faculty Publications

Resting CD4+ T-cells harboring inducible HIV proviruses are a critical reservoir in antiretroviral therapy (ART)-treated subjects. These cells express little to no viral protein, and thus neither die by viral cytopathic effects, nor are efficiently cleared by immune effectors. Elimination of this reservoir is theoretically possible by combining latency-reversing agents (LRAs) with immune effectors, such as CD8+ T-cells. However, the relative efficacy of different LRAs in sensitizing latently-infected cells for recognition by HIV-specific CD8+ T-cells has not been determined. To address this, we developed an assay that utilizes HIV-specific CD8+ T-cell clones as biosensors for HIV antigen expression. By testing …

Variability Of Objectively Measured Sedentary Behavior, Seth C. Donaldson, Alexander H. K. Montoye, Mary T. Imboden, Leonard A. Kaminsky

Faculty Publications - Department of Kinesiology

The primary purpose of this study was to evaluate variability of sedentary behavior (SB) throughout a 7-d measurement period and to determine if G7 d of SB measurement would be comparable with the typical 7-d measurement period. Methods: Retrospective data from Ball State University_s Clinical Exercise Physiology Laboratory on 293 participants (99 men, 55 T 14 yr, body mass index = 29 T 5 kgImj2; 194 women, 51 T 12 yr, body mass index = 27 T 7 kgImj2) with seven consecutive days of data collected with ActiGraph accelerometers were analyzed (ActiGraph, Fort Walton Beach, FL). Time spent in SB …

Is Ca-125 The Leading Biomarker In Determining Early-Onset Ovarian Cancer Diagnosis In 2016?, Alexa Clark

Senior Honors Projects

Epithelial ovarian cancer is the most lethal gynecologic malignancy with very ineffective efforts at early detection and therapeutic methodologies to reduce mortality. The origin and pathogenicity of ovarian cancer is vastly unclear, which is why diagnosing the disease early on is difficult. CA-125 is a used as therapeutic tumor marker for ovarian cancer, but it is not diagnostic or specific. The role of CA-125 in the early detection of ovarian cancer is extremely controversial and has not been widely accepted for screening in women who do not show any symptoms. In order to enhance the sensitivity for early disease detection …

Factors Leading To Rapid Response Team Interventions In Adult Medical-Surgical Patients, Christine Tarver, Diane Stuenkel

Faculty Publications

The effectiveness of a Rapid Response Team Intervention (RRTI) in preventing transfer to a higher level of care and decreasing in-hospital mortality has not been firmly established. This retrospective exploratory study examined differences between medical-surgical patients who had an RRTI and those who did not. Results yielded 5 statistically significant differences (P

Serotonin As A Putative Scavenger Of Hypohalous Acid In The Brain, Mike Kalogiannis, E James Delikatny, Thomas M. Jeitner

NYMC Faculty Publications

Neurodegenerative disorders represent the culmination of numerous insults including oxidative stress. The long etiology of most of these disorders suggests that lessening the effects of one or more of the insults could significantly delay disease onset. Antioxidants have been tested as possible therapeutics for neurodegenerative disorders, but with little success. Here we report that serotonin acts as a scavenger of hypochlorous acid (HOCl) in the brain. Serotonin was shown to prevent the oxidation of 2-thio-5-nitrobenzoate by HOCl in a biphasic manner. The first phase was a partial scavenging that occurred at concentrations of serotonin that exceeded those of HOCl. (1)H-NMR …

Translating Genomic Advances To Physical Therapist Practice: A Closer Look At The Nature And Nurture Of Common Diseases, Catherine L. Curtis, Allon Goldberg, Jeffrey A. Kleim, Steven L. Wolf

NYMC Faculty Publications

The Human Genome Project and the International HapMap Project have yielded new understanding of the influence of the human genome on health and disease, advancing health care in significant ways. In personalized medicine, genetic factors are used to identify disease risk and tailor preventive and therapeutic regimens. Insight into the genetic bases of cellular processes is revealing the causes of disease and effects of exercise. Many diseases known to have a major lifestyle contribution are highly influenced by common genetic variants. Genetic variants are associated with increased risk for common diseases such as cardiovascular disease and osteoarthritis. Exercise response also …

Award-Winning Documentary 'A Certain Kind Of Light', Loma Linda University Health

Scope

Table of Contents:

Campus News

2 | Campus transformation is well underway
4 | Terror in San Bernardino
6| Children's Hospital receives new head coach
7| Bailey among 50 'stars' honored for Flag for Hope

Wholeness

8 | 'A Certain Kind of Light' documentary premires
10 | Prayer notes inspire with winning images
11 | Spiritual plan will help steer Loma Linda University Health

Clinical Care

12 | Behavioral Medical Center celebrates 25 years
14 | Liver recipients at Transplantation Institute live longer
14 | New affiliation with Southern Mono Healthcare District
15 | Future rabbi shares story at 25th …

Promoting Access To Condoms For Youth In Mississippi Through Community Interventions, Harvard Law School Mississippi Delta Project

Delta Directions: Publications

This report is written in collaboration with Mississippi First to assist them in their efforts to increase access to condoms for adolescents and young adults in Mississippi, with a particular focus on the Delta Region. Spurred by high rates of teen pregnancy and sexually transmitted infections in the state, Mississippi First has long been working to empower Mississippi youth by giving them the knowledge and means to make informed decisions. In 2014, Mississippi First created the Mississippi Youth Council (“MYCouncil”) to “ensure that young people in Mississippi have a voice in the debate around their sexual and reproductive health, education, …

College Of Health Professions News, Spring 2016, College Of Health Professions

College of Health Professions Newsletters & Magazines

No abstract provided.

Sex And Sexual Education In China: Traditional Values And Social Implications, Isabella Steinhauer

Independent Study Project (ISP) Collection

In China, the differing views of sex between younger and older generations is the clearest indicator ofthe division of modern and traditional thought in societyand their resulting repercussions. The paper examineswhat specific traditional Chinese norms and values spark many social issues in China, how those traditional values are reflected in the lack of sexual education, and then analyzes how the lack of sexual education impacts those social issues.Formal interviews were conducted in Kunming with seven college students (aged 18-23) from Yunnan Finance and Economics University and other universities, while more casual conversations were held with people of other ages in …

Tools And Methods For Zika Prevention In Cachoeira, Bahia, Florence Tesha

Independent Study Project (ISP) Collection

Zika virus, which is mainly transmitted by Aedes aegypti and Aedes albopictus mosquitoes, has become a major health threat in Brazil and other Latin American countries. Brazil is the country that is being most impacted with zika virus in addition to the existing mosquito-borne diseases of dengue and chikungunya. With the increase in zika virus infections, there have also been increasing numbers of infant brain abnormalities such as microcephaly associated to zika. International and local health institutions are working together to control and prevent zika transmission. This project aimed to investigate the various tools and methods employed by the Center …

Neglect Amidst The Zika Epidemic: A Case Study On The Reach Of Government Campaigns And Resources In Quilombo Community Praia Grande, Bahia, Jenna Sherman

Independent Study Project (ISP) Collection

In response to the ongoing Zika epidemic in Brazil, a nationwide campaign has recently been launched targeting the eradication of mosquitoes, preventing the contraction of Zika, and deterring pregnancies. Many remote areas of Brazil, however, may not be being reached by these campaigns or resources to the same extent as more urban or affluent areas of Brazil—despite the existence of the universal healthcare system Sistema Único de Saúde (SUS). My objective, therefore, is to assess which media and on-ground campaigns regarding Zika have reached the minute island town of Praia Grande—a rural fishing Quilombo community of approximately 2,000 occupants off …

Obstetric Violence Within The Brazilian Healthcare System: A Critical Analysis Of The Childbirth Narratives Of Tupinambá Indigenous Women From The Olivença, Ilhéus Community, Cassandra Fareira

Independent Study Project (ISP) Collection

The objective of this research project is to hear the personal narratives of Tupinambá Indigenous Brazilian women living in the Olivença community in Ilheus, Bahia regarding their experiences giving birth in order to discern the prevalence of various forms of obstetric violence within their experiences. In the context of this study the term "obstetric violence," derived from an extensive literature review, encompasses 1) physical abuse, 2) the unethical imposition of medical interventions, 3) the denial or lack of privacy, 4) undignified care which includes verbal abuse, 5) discrimination, 6) abandonment, neglect or the refusal to grant assistance, 7) detention in …

El Método Anticonceptivo Implante Subdérmico Para Prevenir La Repetición Del Embarazo Adolescente En La Provincia De Tucumán, Madelaine Hack

Independent Study Project (ISP) Collection

Información Contextual: El método anticonceptivo implante subdérmico se utiliza para prevenir la repetición del embarazo adolescente entre mujeres de 14 a 24 años de edad que no tienen cobertura de salud (es decir, sin cobertura de una obra-social o pre-paga) y que han tenido un evento obstétrico (parto o aborto) en los últimos 12 meses. La prevención del segundo embarazo adolescente es una línea estratégica sumamente importante porque la tasa de embarazo adolescente ha mantenido su valor cercano al 15% por los últimos 20 años. En el caso particular de la provincia de Tucumán, está presenta un contexto interesante lo …

La Accesibilidad Al Test De Vph Y Al Papanicolaou Para La Prevención Del Cáncer Cervicouterino En Servicios Públicos De Salud En San Miguel De Tucumán Según La Perspectiva De Los Profesionales De Salud, Eve Cleghorn

Independent Study Project (ISP) Collection

Información contextual: El cáncer cervicouterino es causado por el Virus del Papiloma Humano (VPH) y todavía es un problema actual en Argentina, con alrededor de 5.000 casos nuevos y 1.800 muertes cada año. Sin embargo, es muy prevenible debido a que es una enfermedad de crecimiento lento, y con herramientas correctas de tamizaje y diagnóstico. Estas incluyen la vacuna contra diferente tipos de VPH de alto riesgo y el Papanicolaou, un procedimiento en el cual se examinan las células del cuello de útero que podrían ser indicios de lesiones pre-cancerosas o cancerosas, las cuales pueden ser tratadas. Además, en unas …

El Uso De Terapias Psicológicas En Mujeres Jóvenes En La Ciudad Autónoma De Buenos Aires (Caba), Argentina, Batsheva Honig

Independent Study Project (ISP) Collection

Información Contextual: Esta investigación se enfoca en el uso de terapia en mujeres jóvenes en la Ciudad de Buenos Aires (CABA), Argentina. Argentina es el líder mundial de psicólogos por habitantes con una gran concentración de psicólogos en CABA (Alonso y Klinar 2014). El uso de terapia no es exclusivo de personas con trastornos mentales. En el ámbito privado son comunes las consultas por cuestiones generales de la vida. La población de este estudio son mujeres jóvenes entre 22 y 32 años. Este periodo es caracterizado como un tiempo de exploración y auto-reflexión. Además, esta franja etaria constituye un gran …

The Changing Roles And Reputations Of Dais In Rural Uttarakhand: An Investigation Into The Maternal Health Services Of Villages In Okhalkanda Block In Nainital, Jenna Davis

Independent Study Project (ISP) Collection

The dai, once a prominent figure in Indian maternal health, now faces marginalization as the government of India adopts the goal of universal institutional delivery. Under pressure from international discourse that Skilled Birth Attendants (SBAs) were more effective at lowering Maternal Mortality Rate (MMR) than Traditional Birth Attendants (TBAs) like dais (World Health Organization), dai training was discontinued and left in the hands of NGOs, while concurrently women and ASHAs were monetarily incentivized for every institutional birth (Park, 419). Yet in rural, isolated, or hilly areas like Okhalakanda block in Uttarakhand, institutional delivery is a long way from universal—only …

A Qualitative Investigation On The Effects Of The Uttar Pradesh Population Policy On Women Who Undergo Sterilization In Bahraich, Uttar Pradesh, Anna Wadhwani

Independent Study Project (ISP) Collection

The effectiveness of population policies is widely disputed by the international development community and is under constant scrutiny. While these policies have the potential to positively affect reproductive and child health indicators, they often focus too heavily on macro-demographic family planning goals and fail to acknowledge socioeconomic determinants of fertility indicators, often making for ineffective policy. Furthermore, target-based approaches have the potential to negatively impact women’s family planning choices and the quality of care they receive. This study seeks to analyze how the Uttar Pradesh Population Policy affects the decision-making process and experiences of women who undergo sterilization procedures in …

Low Radiation Dose Calcium Scoring: Evidence And Techniques, Kaitlin B. Baron, Andrew D. Choi, Marcus Y. Chen

Medicine Faculty Publications

Coronary computed tomography (CT) allows for the acquisition of thin slices of the heart and coronary arteries, which can be used to detect and quantify coronary artery calcium (CAC), a marker of atherosclerotic cardiovascular disease. Despite the proven clinical value in cardiac risk prognostication, there remain concerns regarding radiation exposure from CAC CT scans. There have been several recent technical advancements that allow for significant radiation dose reduction in CAC scoring. This paper reviews the clinical utility and recent literature in low radiation dose CAC scoring.

Cerebral Malaria: An Unusual Case Of Central Diabetes Insipidus, Resmi Premji, Nira Roopnarinesingh, Joshua Cohen, Sabyasachi Sen

Medicine Faculty Publications

Central diabetes insipidus is an uncommon feature of malaria. A previously healthy 72-year-old man presented with fever, rigors, and altered mental status after a recent trip to Liberia, a country known for endemic falciparum malaria. Investigations confirmed plasmodium falciparum parasitemia. Within one week after admission, the serum sodium rose to 166 mEq/L and the urine output increased to 7 liters/day. Other labs were notable for a high serum osmolality, low urine osmolality, and low urine specific gravity. The hypernatremia did not respond to hypotonic fluids. Diabetes insipidus was suspected and parenteral desmopressin was started with a prompt decrease in urinary …

An Intensive Aphasia Needs Assessment Tool, Dalana Marie Henson

Masters Theses & Specialist Projects

Persons with aphasia (PWAs) often demonstrate challenges in the areas of expressive language, comprehension, reading, and writing. Due to these deficits, PWAs have limited opportunity to express their opinions and contribute to treatment planning. This project focused on the development of a self-report needs assessment tool for PWAs that facilitates PWAs participation in treatment planning. The needs assessment tool was designed using aphasia-friendly features including pictographic/visual analog scale, key words in bold, simple wording, large font, consistent question formatting, flexible administration, and the use of a communication partner/interview. The needs assessment tool was administered to seven PWAs in the Bowling …

The Dawn Of De-Extinction. Are You Ready? Ted Talk Annotated Resource List, Benjamin Paul Watson

Undergraduate Research Award

No abstract provided.