Medicine and Health Sciences Commons^™

What's Happening: May 23, 2016, Maine Medical Center

What's Happening

No abstract provided.

Erosion Of Empathy In Primary Care Trainees, Jacquelyn Mcrae, Pharmd, G. Calusi, Mengdan Liu, V. Scognamiglio, E. Messina, L. Polenzani, Vittorio Maio, Pharmd, Msph

College of Population Health Posters

Objective:

To evaluate if empathy among physician residents (trainees) differs dependent on training year and to assess trainees' characteristics associated with higher empathy scores.

Poster presented at 2016 ISPOR conference in Washington DC.

A Review Of Current Quality Metrics For Evaluating Patient-Centered Medical Homes, Stefan Varga, M. Lombardi, Vittorio Maio, Pharmd, Msph

College of Population Health Posters

Objectives:

This review sought to explore the quality metrics that are currently utilized to assess PCMHs

Poster presented at 2016 ISPOR conference in Washington DC.

From Jim Crow To Racial Tolerance: The African-American Experience During Interwar Period Paris, Nicole Schindel

Binghamton University Undergraduate Journal

During World War I, African-American soldiers came to France and discovered the relative diminishment of racial prejudices in the country. Since much of the United States still held racist Jim Crow era laws and prejudices, African-Americans had been barred from the same opportunities as their white counterparts. Because of this, many African- Americans moved to Paris during the interwar period to seek opportunities that were not available to them in the United States. This paper will explore how the less rigid and more nuanced racial ideologies found in Paris, enabled African-Americans to create strong relationships with Parisians and find the …

Changes In The Adult Glun2b Associated Proteome Following Adolescent Intermittent Ethanol Exposure, H. Scott Swartzwelder, Mary-Louise Risher, Kelsey M. Miller, Roger J. Colban, Danner G. Winder, Tiffany A. Wills

Biomedical Sciences

Adolescent alcohol use is the strongest predictor for alcohol use disorders. In rodents, adolescents have distinct responses to acute ethanol, and prolonged alcohol exposure during adolescence can maintain these phenotypes into adulthood. One brain region that is particularly sensitive to the effects of both acute and chronic ethanol exposure is the hippocampus. Adolescent intermittent ethanol exposure (AIE) produces long lasting changes in hippocampal synaptic plasticity and dendritic morphology, as well as in the susceptibility to acute ethanol-induced spatial memory impairment. Given the pattern of changes in hippocampal structure and function, one potential target for these effects is the ethanol sensitive …

Womanhood Initiation, Anna Szilagyi

Binghamton University Undergraduate Journal

Womanhood Initiation is a poem I wrote during Maria Gillan's Advanced Poetry Workshop. Professor Gillan is a Professor of English at Binghamton University, and her workshop is unique in that it takes place during three long weekend sessions throughout the semester. This specific poem was inspired by one of Professor Gillan’s writing prompts: “I do not feel like a man/woman yet.” I tend to explore gender in my poetry, specifically girlhood and womanhood. Young women and girls, often put down in United States culture for their vanity and selfishness, are complex, intelligent people and have more to say that should …

Examining Primarily White Institutions Of Higher Education: Black Student Experience In The 1960s, Oluwashola Gbemi

Binghamton University Undergraduate Journal

A major outcome of the Civil Rights Act of 1964 was the desegregation of higher-learning institutions. Despite this, there was little change regarding the character and cultural norms of predominantly white institutions (PWIs) of higher learning. In this review of literature discussing the experiences of Black students attending PWIs during the 1960s, I argue that cultural norms such as racial discrimination yielded a detrimental impact on the success and wellbeing of African-American students. While I discuss what quality wellbeing for African-American students entails, I highlight the significance of black student unions to the wellbeing of black students. In order to …

Challenging Linguistic Superiority Through Social Attitudes: Language Complexities Of The Ukrainian Diaspora In The United States, Anna Pinchuk

Binghamton University Undergraduate Journal

The English language in the United States has a strong legacy of linguistic imperialism that started with bans on the use of languages spoken by indigenous people in the early 1800s. The assumptions behind those policies were that the English language was civilized and progressive, while all other languages were barbaric and improper. In this paper, I examine how the historic language policies in the United States continue to create barriers in non-native speakers’ success and achievement in social and political spheres. I proceed by discussing the English-only policies and native language bans that started the legacy of English superiority …

Do Natural Disasters Induce More Crime?, Michael Lentini, Plamen Nikolov, Matthew Schwartz

Binghamton University Undergraduate Journal

The Indian Ocean Tsunami of 2004 resulted in grave consequences for South East Asia. Indonesia, in particular, had the highest death toll, losing over 150,000 people. Indonesia’s coastal region Aceh was the hardest hit by this disaster. Exploiting exogenous spatial variation at the district level, we use difference-in-difference analysis to estimate the causal effect of the 2004 disaster on subsequent crime rates. We find that after the tsunami, total annual crime rate went down, on average, by 244 crimes per annum.

A Retrospective, Single Center Experience With The Sharkcore Fine Needle Biopsy System: A New Bite In To Gastrointestinal Histological Sampling, Bonnie Patek Do, Joan Collette Crn, Hope Kincaid Mph, Cph, Jennifer E. Macfarlan Mph, Shashin Shah Md, Hiral N. Shah Md

Department of Medicine

No abstract provided.

Reengineering Of Mesh Thesauri For Term Selection To Optimize Literature Retrieval And Knowledge Reconstruction In Support Of Stem Cell Research, Yan Su, James E. Andrews, Hong Huang, Yue Wang, Liangliang Kong, Peter Cannon, Ping Xu

School of Information Faculty Publications

BACKGROUND: PubMed is a widely used database for scientists to find biomedical-related literature. Due to the complexity of the selected research subject and its interdisciplinary nature, as well as the exponential growth in the number of disparate pieces of biomedical literature, it is an overwhelming challenge for scientists to define the right search strategies and quickly locate all related information. Specialized subsets and groupings of controlled vocabularies, such as Medical Subject Headings (MeSH), can enhance information retrieval in specialized domains, such as stem cell research. There is a need to develop effective search strategies and convenient solutions for knowledge organization …

Mental Health Initiatives For Asian American Women, Karen Lin

Binghamton University Undergraduate Journal

Despite being one of the fastest growing minorities of the United States, Asian Americans are most at risk for developing mental disorders and least likely to seek professional help. With a significant portion of the United States represented by Asian ethnicities, addressing the mental health needs of this population is not only important but necessary to advance the overall health of all Americans. The purpose of this paper is to describe the influences of cultural norms and standards that increase risk factors for poor mental health outcomes and negative help seeking attitudes in first generation Asian American college-aged females. These …

The Structure And Regulation Of Cullin 2 Based E3 Ubiquitin Ligases And Their Biological Functions., Weijia Cai, Haifeng Yang

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

BACKGROUND: Cullin-RING E3 ubiquitin ligase complexes play a central role in targeting cellular proteins for ubiquitination-dependent protein turnover through 26S proteasome. Cullin-2 is a member of the Cullin family, and it serves as a scaffold protein for Elongin B and C, Rbx1 and various substrate recognition receptors to form E3 ubiquitin ligases.

MAIN BODY OF THE ABSTRACT: First, the composition, structure and the regulation of Cullin-2 based E3 ubiquitin ligases were introduced. Then the targets, the biological functions of complexes that use VHL, Lrr-1, Fem1b, Prame, Zyg-11, BAF250, Rack1 as substrate targeting subunits were described, and their involvement in diseases …

Suppression Of Progranulin Expression Inhibits Bladder Cancer Growth And Sensitizes Cancer Cells To Cisplatin., Simone Buraschi, Shi-Qiong Xu, Manuela Stefanello, Igor Moskalev, Alaide Morcavallo, Marco Genua, Ryuta Tanimoto, Ruth Birbe, Stephen C. Peiper, Leonard G. Gomella, Antonino Belfiore, Peter C. Black, Renato V. Iozzo, Andrea Morrione

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

We have recently demonstrated a critical role for progranulin in bladder cancer. Progranulin contributes, as an autocrine growth factor, to the transformed phenotype by modulating Akt-and MAPK-driven motility, invasion and anchorage-independent growth. Progranulin also induces F-actin remodeling by interacting with the F-actin binding protein drebrin. In addition, progranulin is overexpressed in invasive bladder cancer compared to normal tissue controls, suggesting that progranulin might play a key role in driving the transition to the invasive phenotype of urothelial cancer. However, it is not established whether targeting progranulin could have therapeutic effects on bladder cancer. In this study, we stably depleted urothelial …

Molecular Identification Of Different Trypanosome Species And Subspecies In Tsetse Flies Of Northern Nigeria, Clement Isaac, Marc Ciosi, Alana Hamilton, Kathleen Maria Scullion, Peter Dede, Igho Benjamin Igbinosa, Oyebiguwa Patrick Goddey Nmorsi, Dan Masiga, C. Michael R. Turner

All Peer-Reviewed Publications

Background: Animal African Trypanosomiasis (AAT) is caused by several species of trypanosomes including Trypanosoma congolense, T. vivax, T. godfreyi, T. simiae and T. brucei. Two of the subspecies of T. brucei also cause Human African Trypanosomiasis. Although some of them can be mechanically transmitted by biting flies; these trypanosomes are all transmitted by tsetse flies which are the cyclical vectors of Trypanosoma congolense, T. godfreyi, T. simiae and T. brucei. We present here the first report assessing the prevalence of trypanosomes in tsetse flies in Nigeria using molecular tools. Methods: 488 tsetse flies of three species, Glossina palpalis palpalis, G. …

Adiponectin Ameliorates The Apoptotic Effects Of Paraquat On Alveolar Type Ⅱ Cells Via Improvements In Mitochondrial Function., Yarong He, Liqun Zou, Yaxiong Zhou, Hai Hu, Rong Yao, Yaowen Jiang, Wayne Bond Lau, Tun Yuan, Wen Huang, Zhi Zeng, Yu Cao

Department of Emergency Medicine Faculty Papers

Previous studies have demonstrated that excessive reactive oxygen/nitrogen species (ROS/RNS)‑induced apoptosis is an important feature of the injury to the lung epithelium in paraquat (PQ) poisoning. However the precise mechanisms of PQ‑induced dysfunction of the mitochondria, where ROS/RNS are predominantly produced, remain to be fully elucidated. Whether globular adiponectin (gAd), a potent molecule protective to mitochondria, regulates the mitochondrial function of alveolar type II cells to reduce PQ‑induced ROS/RNS production remains to be investigated. The current study aimed to investigate the precise mechanisms of PQ poisoning in the mitochondria of alveolar type II cells, and to elucidate the role of …

A Bi-Stable Switch In Virus Dynamics Can Explain The Differences In Disease Outcome Following Siv Infections In Rhesus Macaques, Stanca Ciupe, Christopher Miller, Jonathan Forde

Biology and Medicine Through Mathematics Conference

No abstract provided.

Patient-Specific Inference Of Average Glucose From Glycated Hemoglobin, Roy Malka, David M. Nathan, John M. Higgins

Biology and Medicine Through Mathematics Conference

No abstract provided.

Determinants Of The Efficacy Of Hiv Latency Reversing Agents And Implications For Drug And Treatment Design, Ruian Ke

Biology and Medicine Through Mathematics Conference

No abstract provided.

Using Mathematical Modeling To Unmask The Concealed Nature Of Long Qt-3 Syndrome, Steven Poelzing, Amara Greer-Short, Seth H. Weinberg

Biology and Medicine Through Mathematics Conference

No abstract provided.

The Influence Of Temperature Variation On Dengue Fever: A Model-Based Investigation, Michael A. Robert, Paula D. Weber, Rebecca C. Christofferson, Christopher N. Mores, Helen J. Wearing

Biology and Medicine Through Mathematics Conference

No abstract provided.

Optimal Insecticide-Treated Bed-Net Coverage And Malaria Treatment In A Malaria-Hiv Co-Infection Model, Eric Numfor

Biology and Medicine Through Mathematics Conference

No abstract provided.

Medical School Watercooler Newsletter - May 22. 2016, Lindsey Lyle

Watercooler Newsletter

This is the May 22, 2016 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• USA Libraries Book Drive A Success
• Two USA College of Medicine Faculty Members Honored With Teaching Awards
• Memorial Service to Remember Dr. Aubrey E. Taylor
• COM Alumni to Reunite at Annual Alumni Weekend

Describing The End Of Life Knowledge, Beliefs, And Preferences Of Alaska Native And American Indian Peoples, Colleen Marie Kelley

Theses and Dissertations

This dissertation is comprised of three manuscripts that will be submitted for publication, describing the end of life knowledge, beliefs, and preferences of Alaska Native and American Indian Peoples. The first manuscript is a literature review that examines what is known about the understanding about the end of life knowledge, beliefs, and preferences of Alaska Native and American Indian Peoples. The second manuscript offers results of an exploratory descriptive study designed to describe the end of life knowledge of hospice care services, beliefs about dying, and preferences for end of life care of Alaska Native and American Indian Peoples. Finally, …

Numerical Study Of The Effect Of Blood Vessel Geometry On Plaque Formation, Lindsey R. Fox

Biology and Medicine Through Mathematics Conference

No abstract provided.

Using Predator Carrying Capacity For A Pathogenic Vector-Dynamic Differential Model, Rosahn P. Bhattarai

Biology and Medicine Through Mathematics Conference

No abstract provided.

Reverse Engineering A Kinetic Model Of A Dopaminergic Neuron To Apoptosis, Johnathan Morris

Biology and Medicine Through Mathematics Conference

No abstract provided.

Demonstration Of Follicle Waves Using Delay Differential Equations, Andrew A. Wright

Biology and Medicine Through Mathematics Conference

No abstract provided.

Heterogeneous Responses To Viral Infection: Insights From Mathematical Modeling Of Yellow Fever Vaccine, James R. Moore

Biology and Medicine Through Mathematics Conference

No abstract provided.

Dynamics Of Two Pathogens In A Single Tick Population, Alexis White

Biology and Medicine Through Mathematics Conference

No abstract provided.