Medicine and Health Sciences Commons^™

Stretching The Boundaries Of Medical Education: A Case Of Medical College Embracing Humanities And Social Sciences In Medical Education, Kulsoom Ghias, Kausar S. Khan, Rukhsana Ali, Shireen Azfar, Rashida Ahmed

Community Health Sciences

Objective:

Aga Khan University, a private medical college, had a vision of producing physicians who are not only scientifically competent, but also socially sensitive, the latter by exposure of medical students to a broad-based curriculum. The objective of this study was to identify the genesis of broad-based education and its integration into the undergraduate medical education program as the Humanities and Social Sciences (HASS) course.

Methods:

A qualitative methodology was used for this study. Sources of data included document review and in-depth key informant interviews. Nvivo software was utilized to extract themes.

Results:

The study revealed the process of operationalization …

Patient Historical Risk Factors Associated With Seizure Outcome After Surgery For Drug-Resistant Nonlesional Temporal Lobe Epilepsy., Ali Akbar Asadi-Pooya, Maromi Nei, Ashwini Sharan, Michael R. Sperling

Department of Neurology Faculty Papers

OBJECTIVE: To investigate the possible influence of risk factors on seizure outcome after surgery for drug-resistant nonlesional temporal lobe epilepsy (TLE).

METHODS: This retrospective study recruited patients with drug-resistant nonlesional TLE who underwent epilepsy surgery at Jefferson Comprehensive Epilepsy Center and were followed for a minimum of one year. Patients had been prospectively registered in a database from 1991 through 2014. Postsurgical outcome was classified into two groups; seizure free or relapsed. The possible risk factors influencing long-term seizure outcome after surgery were investigated.

RESULTS: Ninety-five patients (42 males and 53 females) were studied. Fifty-four (56.8%) patients were seizure free. …

Acute Post-Disaster Medical Needs Of Patients With Diabetes: Emergency Department Use In New York City By Diabetic Adults After Hurricane Sandy., David C. Lee, Vibha K. Gupta, Brendan G. Carr, Sidrah Malik, Brandy Ferguson, Stephen P. Wall, Silas W. Smith, Lewis R. Goldfrank

Department of Emergency Medicine Faculty Papers

OBJECTIVE: To evaluate the acute impact of disasters on diabetic patients, we performed a geospatial analysis of emergency department (ED) use by New York City diabetic adults in the week after Hurricane Sandy.

RESEARCH DESIGN AND METHODS: Using an all-payer claims database, we retrospectively analyzed the demographics, insurance status, and medical comorbidities of post-disaster ED patients with diabetes who lived in the most geographically vulnerable areas. We compared the patterns of ED use among diabetic adults in the first week after Hurricane Sandy's landfall to utilization before the disaster in 2012.

RESULTS: In the highest level evacuation zone in New …

Examination Of Bar Velocity In Barbell Back Squat, Kimitake Sato, Kevin M. Carroll, Michael H. Stone

ETSU Faculty Works

The aim of the study was to examine repetition to repetition changes of bar velocity and its variations from barbell back squat. Participants (N=19) performed back squat with a relative intensity of 78-80% of 1 RM. Bar velocity was captured using wireless device (PUSHtm) placed on their forearm. Data were collected from 3 sets of 10 repetitions. One-way repeated measures ANOVA was used to identify the velocity changes over 10 repetitions. Statistical significance was found (F(1,17)=45.06.~ 0 . 0 0 0 1 )T.h is indicates that the bar velocity decreased significantly over the 10 repetitions. At the same time, coefficient …

Research News. Grants, 2016. Volume 1, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Grants (2015-)

Grants and contracts awarded during January-June 2016

Mechanical Properties Of Copper-Nickel-Titanium Archwires, Margaret Amelia Rosen

Master's Theses (2009 -)

Introduction: The initial phase of orthodontic therapy relies on flexible wires, usually composed of a nickel-titanium alloy, to apply a substantially constant load during tooth movement. Copper has been added to nickel-titanium archwires, resulting in an alloy with potential clinical advantages such as a lower stress hysteresis. Many orthodontic companies claim that their copper-nickel-titanium manufacturing process allows for the production of more consistent transition temperatures in the wires, allowing the orthodontist to customize treatment to various patients based on the force level needed. There are currently many manufacturers of these wires, creating a wide range of copper-nickel-titanium archwires from which …

Snpredict: A Machine Learning Approach For Detecting Low Frequency Variants In Cancer, Vatsal Mehra

Master's Theses (2009 -)

Cancer is a genetic disease caused by the accumulation of DNA variants such as single nucleotide changes or insertions/deletions in DNA. DNA variants can cause silencing of tumor suppressor genes or increase the activity of oncogenes. In order to come up with successful therapies for cancer patients, these DNA variants need to be identified accurately. DNA variants can be identified by comparing DNA sequence of tumor tissue to a non-tumor tissue by using Next Generation Sequencing (NGS) technology. But the problem of detecting variants in cancer is hard because many of these variant occurs only in a small subpopulation of …

Rna-Seq Analysis Of Localized Mst1/Stk4 Expression In Prostate Cancer, Damien Ready

Master's Theses (2009 -)

The SKT4-encoded MST1 is a serine-threonine protein kinase and has known associations with many diseases and cancer.MST1 plays a critical component of the Hippo tumor suppressor pathway responsible for limiting cell division and promoting apoptosis.Loss of MST1 function is associated with poor prognostic outcomes for cancers, though the mechanism is not well understood.There is increasing evidence that dysregulation of MST1 can lead to castration-resistant prostate cancer (CRPCa), an aggressive cancer with limited treatment options.To better understand the mechanistic underpinnings of CRPCa progression, C4-2 prostate cancer cells were engineered toexpress MST1 protein directed to a particular subcellular region: membrane, nucleus, or …

The Effect Of Orthodontic Appliances On The Evaluation Of The Professionalism And Esthetics Of An Adult Employee, Laura Hanson Vaccariello

Master's Theses (2009 -)

This study explored the influence of fixed and removable orthodontic appliances on participants’ ratings of the job performance, intelligence, and attractiveness of an adult female. Ninety-four adult subjects were recruited from the Graduate School of Management at Marquette University. Each subject received an identical employee performance review with an attached photograph of a female employee. The smile of the photo was manipulated to represent one of four conditions: no orthodontic appliance, a metal orthodontic appliance, a ceramic orthodontic appliance, or a clear aligner. Subjects then rated the employee on three continuous Likert scales. Ratings of job performance, intelligence, and attractiveness …

The Effects Of Mechanical Vibration On Human Chondrocytes In Vitro, Bradley J. Gauthier

Master's Theses (2009 -)

Introduction: Inflammation is the biological basis of temporomandibular joint disorders (TMD), when severe it can lead to osteoarthritis. One of the physical therapies used to manage this condition is mechanical vibration, as has been used in medicine for many years as a non-pharmacological therapy. Recently an FDA approved dental device called AcceleDent has been introduced to increase the rate of tooth movement and decrease pain. As the device-generated vibration transmits to the TMJ, it is important for us to investigate whether mechanical vibration influences TMJ on its biologic basis – chondrocytes under normal and inflammatory conditions. Materials and Methods: Human …

The Effect Of Mechanical Vibration On Human Pdl Cell Differentiation And Response To Inflammation, Megan Desroches

Master's Theses (2009 -)

Low magnitude mechanical vibration is a therapeutic adjunct being investigated to alter bone remodeling and inflammation in areas such as osteoporosis, bone fracture healing, and muscle soreness after exercise. In orthodontics a device named AcceleDent has been marketed that claims to increase the rate of tooth movement and decrease pain. However evidence for these claims is lacking. In this study we looked at two potential cellular mechanisms for these claims: periodontal ligament (PDL) cell differentiation and inflammation under an orthodontic model of strain (IL-1β). Increased PDL cell differentiation into osteogenic cells could be an avenue of increasing orthodontic tooth movement. …

The Effect Of Marital Therapy On Physical Affection, Tiffany Ann Migdat

Theses and Dissertations

Research indicates that marital satisfaction is associated with levels of physical affection between partners. This is important because there is evidence of physical and mental health benefits of physical affection. Although past research has shown that marital therapy increases levels of marital and sexual satisfaction, the association between marital therapy and physical affection has not been explored. This study used a treatment group and a control group of 108 married couples to assess the relationship between marital therapy and physical affection over a course of 12 weeks. Using structural equation modeling and an actor partner analytic model, results indicated that …

Does Self-Esteem Mediate The Effect Of Attachment On Relationship Quality, Alexis Lee

Theses and Dissertations

The purpose of this study was to examine the possible mediating effect of self-esteem on the relationship between attachment security and relationship quality. Previous studies have found a positive association between attachment style and relationship quality. One possible explanation for this link may be self-esteem, which has been shown to consistently predict relationship quality. Therefore, I hypothesized that self-esteem may mediate the relationship between attachment and relationship quality. A sample of 680 married couples that completed the sections on attachment, self-esteem, marital satisfaction, marital stability, and problem areas in the relationship of the RELATE questionnaire between 2011 and 2013 was …

Pathways To Marriage: Relationship History And Emotional Health As Individual Predictors Of Romantic Relationship Formation, Garret Tyler Roundy

Theses and Dissertations

The process of forming a committed, romantic relationship is described as a developmental phenomenon that cannot be accurately viewed without the context of prior relationship experiences because the social competencies that facilitate successful navigation of the tasks of relationship formation are developed in relationships. Furthermore, a cumulative relationship history that has a negative influence may lead to poor emotional health, further disrupting relationship formation processes through that mechanism. Hypotheses were tested using data from a prospective longitudinal study of participants (218 women, 174 men) who were not in a romantic relationship at initial data collection and reported on their relationship …

A Comparison Between Optical Coherence Tomography Angiography And Fluorescein Angiography For The Imaging Of Type 1 Neovascularization., Maiko Inoue, Jesse J. Jung, Chandrakumar Balaratnasingam, Kunal K. Dansingani, Elona Dhrami-Gavazi, Mihoko Suzuki, Talisa E. De Carlo, Abtin Shahlaee, Michael A. Klufas, Adil El Maftouhi, Jay S. Duker, Allen C. Ho, Maddalena Quaranta-El Maftouhi, David Sarraf, K. Bailey Freund

Wills Eye Hospital Papers

Purpose: To determine the sensitivity of the combination of optical coherence tomography angiography (OCTA) and structural optical coherence tomography (OCT) for detecting type 1 neovascularization (NV) and to determine significant factors that preclude visualization of type 1 NV using OCTA.

Methods: Multicenter, retrospective cohort study of 115 eyes from 100 patients with type 1 NV. A retrospective review of fluorescein (FA), OCT, and OCTA imaging was performed on a consecutive series of eyes with type 1 NV from five institutions. Unmasked graders utilized FA and structural OCT data to determine the diagnosis of type 1 NV. Masked graders evaluated FA …

Relationship Of Tumor Thickness With Neck Node Metastasis In Buccal Squamous Cell Carcinoma: An Experience At A Tertiary Care Hospital, Sadaf Qadeer Ahmed, Montasir Junaid, Sohail Awan, Moaz M. Choudhary, Maliha Kazi, Aria Masoom, Hareem Usman Khan

Department of Surgery Docs

Introduction Squamous cell carcinoma is the most common malignancy of the head and neck, with the buccal mucosa being the most common site involved. Early locoregional metastasis is a hallmark of this disease, and early stage tumors may harbor metastatic nodes that are occult. Certain parameters can help identify high-risk patients for whom the pattern of occult nodal metastasis can be predicted. Tumor thickness is one such objective parameter. Objective To determine the relationship of tumor thickness with neck node metastasis in squamous cell carcinoma of the buccal mucosa. Methods A retrospective chart review of 102 patients with biopsy-proven squamous …

Comparison Of Ureteric Stone Size, On Bone Window Versus Standard Soft-Tissue Window Settings, On Multi-Detector Non-Contrast Computed Tomography., Hussam Uddin Soomro, Hammad Ather, Basit Salam

Department of Surgery Docs

Abstract

OBJECTIVE:

To compare the difference in mean stone size, as measured on bone window vs standard soft-tissue window setting using multi-detector computed tomography (MDCT) in patients with a solitary ureteric stone.

PATIENTS AND METHODS:

In all, 60 patients presenting to the emergency and outpatient departments of a University Hospital from May 2015 to October 2015 and fulfilling the inclusion criteria were included in the study. A 64-slice MDCT was used to assess the locations and size of the ureteric stones. A consultant radiologist independently analysed the MDCT scans of all the patients. The mean difference in stone size was …

The Information-Motivation-Behavioral Skills Model: An Examination Of Obesity Prevention Behavioral Change In Children Who Participated In The Afterschool Program Virginia Beach Let’S Move, Marilyn Miroshlava Bartholmae

Health Services Research Dissertations

The purpose of this study was to examine the utility of the Information-Motivation-Behavioral Skills Model (IMB) as a foundation to design childhood obesity prevention afterschool programs. This study employed a secondary analysis of pre (n=172), post (n=170), and 1-year follow-up (n=32) evaluations of the obesity prevention afterschool program Virginia Beach Let’s Move for children ages 5-11 years. Independent variables included demographic characteristics for the participating children and their parents. Dependent variables used in this study were the IMB constructs information and motivation. Motivation was measured by the attitudes of the children and information was measured by the children’s knowledge.

The …

12-Day Adventure Run-Hike Training At Altitude Improves Sea Level 5km Performance, Andrew M. Jones

All NMU Master's Theses

Elite and recreational endurance athletes routinely seek strategies to enhance sea level (SL) performance. Altitude (ALT) training continues to be an appealing approach. The primary purpose of this study was to measure the effect of a 12-day adventure running camp at ALT on 5 km time trial (TT) performance at SL. Secondarily, we explored changes in select metabolic and blood variables. We hypothesized an improvement in TT at SL. A group of five well-trained individuals (2 females) volunteered. TT, maximal oxygen uptake (VO₂max), running economy (RE), and a complete blood count (CBC) were measured at SL before and …

Introduction To The Special Section: Positive Developmental Strategies For Engaging Emerging Adults And Improving Outcomes, Janet S. Walker, Celeste Seibel, Sharice Jackson, John D. Ossowski

School of Social Work Faculty Publications and Presentations

As compared to any other age cohort in the US population, young people in late adolescence and early adulthood have a higher rate of unmet need for mental health services. Not only are these young people (from about 16 to 25 years old, and referred to here as “emerging adults”) more likely to experience a serious mental health condition (SMHC), but they are also less likely to engage in services. Furthermore, when emerging adults do engage in services, they face multiple barriers to service continuity, particularly as they come up to “milestone” ages at 18, 21, and 24.

There is …

"It's Such A Battle": A Phenomenological Account Of Raising A Child On The Autistic Spectrum - A Battle With Bureaucracy And Behaviour, Tara Vassallo

The Plymouth Student Scientist

A sharp rise in the prevalence of Autism Spectrum Disorder (ASD), has led to it becoming one of the most widely researched neurodevelopmental conditions. Although the predominant focus in autism research is child centred, research on parent outcomes has highlighted considerable impact, in terms of parent’s mental health and wellbeing. Previous studies have shown that parents of children with autism suffer extremes of distress, in excess of that of parents of children with other disabilities. However, why this is so is less understood. Interpretative phenomenological analysis was used to analyse data, gathered from semi-structured interviews of seven parents raising children …

The Scoop, Vol. 3 Issue 3-4, Summer 2016, Health Sciences Library

Volume 3

Latest news and events from the Health Sciences Library in our monthly newsletter for Summer 2016.

In-Vitro Comparison Of Micro-Leakage Between Nanocomposite And Microhybrid Composite In Class V Cavities Treated With The Self-Etch Technique, Syeda Mahvish Hussain, Farhan Raza Khan

Department of Surgery Docs

Abstract

BACKGROUND:

When a light cure composite resin is used to restore a class V lesion, certain stresses are generated at the tooth-restoration interface. If these stresses exceed the bond strength of the restorative material, microscopic gaps are formed which eventually cause micro-leakage at the tooth-restoration interface. The objective of the present study was to compare the micro-leakage values at the tooth-restoration interface using dye penetration method between a Nano filled and a Micro hybrid light cured composite resin in class V cavities using the self-etch technique.

METHODS:

Sixty class V cavities were made coronal to the cemento-enamel junction in …

Comparison Of Iron Supplementation And Albendazole On Anemia In Ghanaian Children, Megan M. Zitting

Theses and Dissertations

Half a billion school aged children suffer from anemia, with the majority of anemia caused by iron deficiency. Researchers have shown a strong correlation between low hemoglobin levels and presence of intestinal parasites in children with anemia. Childhood anemia has profound negative effects on physical growth, maturation, and cognitive development leading to poorer educational achievement. Using hemoglobin as a measure of anemia, this quasi-experimental study investigated impact of either iron supplementation or an antiparasitic medication on hemoglobin levels in two groups of children in a rural region of Eastern Ghana. Surprisingly, after a 6-month intervention period, hemoglobin levels in both …

High-Throughput Screening Of Clinically Approved Drugs That Prime Polyethylenimine Transfection Reveals Modulation Of Mitochondria Dysfunction Response Improves Gene Transfer Efficiencies, Albert Nguyen, Jared P. Beyersdorf, Jean-Jack Riethoven, Angela K. Pannier

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Nonviral gene delivery methods are advantageous over viral vectors in terms of safety, cost, and flexibility in design and application, but suffer from lower gene transfer efficiency. In addition to modifications to nucleic acid design and nonviral carriers, new tools are sought to enhance transfection. Priming is the pharmacological modulation of transfection efficiency and transgene expression, and has demonstrated transfection increase in several compounds, for example, chloroquine and glucocorticoids. To develop a library of transfection priming compounds, a highthroughput screen was performed of the NIH Clinical Collection (NCC) to identify clinical compounds that prime polyethylenimine (PEI) transfection. HEK293T cells were …

Engaging African Americans In Developing An Intervention To Reduce Breast Cancer Recurrence: A Brief Report, Selina A. Smith, Mary S. Whitehead, Joyce Q. Sheats, Brittney Fontenot, Ernest Alema-Mensah, Benjamin Ansa

Journal of the Georgia Public Health Association

Background: To develop a culturally appropriate lifestyle intervention, involvement of its intended users is needed.

Methods: Members of an African American (AA) breast cancer support group participated in two 4-hour guided discussions, which were audiotaped, transcribed, and analyzed to guide the content.

Results: The support group collaborated with researchers to develop 24 experiential nutrition education sessions using a social cognitive framework and incorporating self-regulation skills (goal-setting, self-monitoring, problem-solving, stimulus control) and social support to enhance self-efficacy for changes in dietary intake.

Conclusions: Community engagement fostered autonomy, built collaboration, and enhanced the capacity of AA breast cancer survivors to participate in …

Assessment Of Distress, Unmet Needs, And Receipt Of Care Plans Among Cancer Survivors In Georgia, Cam Escoffery, Angie Patterson, Nancy M. Paris, Logan Kirsch, Cassiopeia Frank, Jean O'Connor

Journal of the Georgia Public Health Association

Background: Cancer survivors have distinctive healthcare needs. The Survivorship Working Group of the Georgia Cancer Control Consortium conducted an assessment to understand the physical, psychological, practical, and spiritual needs of adult cancer survivors; patient perceptions regarding patient-provider communications; and their perceived need for services.

Methods: In 2014, a convenience sample of Georgia cancer survivors completed a paper or online survey about the presence of and distress associated with unmet physical, emotional, spiritual, and practical needs, and receipt of assistance in those areas. They were also asked about receipt of cancer treatment and survivorship care plans.

Results: Survivors were primarily female, …

From Offline To Online: How Health Insurance Policies Drive The Demand For Online Healthcare Service?, Yue Yu, Qiu-Yan Mei, Qiu-Hong Wang

Research Collection School Of Computing and Information Systems

Online healthcare service has gradually become a significant part of healthcare services, especially in emerging economy with shortage in medical resources and wide coverage in the Internet usage. This paper studies how health insurance policies affect the demand for online healthcare consultation by using longitudinal online healthcare and offline medical services datasets of a major city in China. The two policies we study are the integration of health insurance systems in urban and rural regions and the integration of health insurance systems between pairwise-cities. The empirical results show that both policies significantly affected the demand for online consultation. Our study …

Student Perceptions Of Scholarly Writing, Shirley P. O'Brien, Dory Marken, Kelsey B. Petrey

EKU Faculty and Staff Scholarship

Learning the process of scholarly writing, including the significance of peer review, is an essential element in the preparation of students for professional practice. This descriptive research study, using Scholarship of Teaching and Learning methodology, explores one approach to teaching scholarly writing in an occupational science/occupational therapy curriculum. The writing assignment was designed to offer multiple points for feedback and revision and instructional features to reinforce learning. A survey of students [n = 169] participating in this scholarly writing project was conducted yearly to gather their perceptions of learning. The results revealed four key elements: instructional strategies are needed …

Integrating Food And Language Nutrition To Reach Georgia’S Children In Early Care And Education Environments, Jean O'Connor, Chinwe Ejikeme, Maria Fernandez, Kia Powell-Threets, Audrey Idaikkadar, Christi Kay, Emily Anne Vall, Kimberly Ross, Brenda Fitzgerald

Journal of the Georgia Public Health Association

Background: Educational attainment and health are mutually reinforcing outcomes. Good health supports children in the achievement of academic milestones, such as grade-level reading, and is associated with higher socio-economic status, longer life expectancy, and lower lifelong chronic disease. Improving health outcomes and increasing the potential for high educational attainment is necessary for reducing disparities, improving population health, and reducing morbidity. Early childhood and associated settings present opportunities to address lifelong health.

Methods: To guide the development of programs to reach large numbers of children, we reviewed the literature associated with interventions during early childhood to promote healthy food consumption patterns …