Medicine and Health Sciences Commons^™

Periodontitis In Chronic Heart Failure, Hanna Fröhlich, Kristina Herrmann, Jennifer Franke, Alamara Karimi, Tobias Täger, Rita Cebola, Hugo A Katus, Christian Zugck, Lutz Frankenstein

The Texas Heart Institute Journal

Periodontal disease has been associated with an increased risk of cardiovascular events. The purpose of our study was to investigate whether a correlation between periodontitis and chronic heart failure exists, as well as the nature of the underlying cause.

We enrolled 71 patients (mean age, 54 ± 13 yr; 56 men) who had stable chronic heart failure; all underwent complete cardiologic and dental evaluations. The periodontal screening index was used to quantify the degree of periodontal disease. We compared the findings to those in the general population with use of data from the 4th German Dental Health Survey.

Gingivitis, moderate …

Psma Targeted Docetaxel-Loaded Superparamagnetic Iron Oxide Nanoparticles For Prostate Cancer, Prashanth K. B. Nagesh, Nia R. Johnson, Vijaya K. N. Boya, Pallabita Chowdhury, Shadi F. Othman, Vahid Khalilzad-Sharghi, Bilal B. Hafeez, Aditya Ganju, Sheema Khan, Stephen Behrman, Nadeem Zafar, Subhash C. Chauhan, Meena Jaggi, Murali M. Yallapu

School of Medicine Publications

Docetaxel (Dtxl) is currently the most common therapeutic option for prostate cancer (PC). However, adverse side effects and problems associated with chemo-resistance limit its therapeutic outcome in clinical settings. A targeted nanoparticle system to improve its delivery to and activity at the tumor site could be an attractive strategy for PC therapy. Therefore, the objective of this study was to develop and determine the anti-cancer efficacy of a novel docetaxel loaded, prostate specific membrane antigen (PSMA) targeted superparamagnetic iron oxide nanoparticle (SPION) (J591-SPION-Dtxl) formulation for PC therapy. Our results showed the SPION-Dtxl formulation exhibits an optimal particle size and zeta …

Genome-Wide Significant Loci For Addiction And Anxiety, Karen Hodgson, Laura Almasy, Emma E. M. Knowles, Jack W. Kent Jr., Joanne E. Curran, Thomas D. Dyer, Harald H. H. Goring, Rene L. Olvera, Peter T. Fox, Godfrey D. Pearlson, J. H. Krystal, Ravindranath Duggirala, John Blangero, David C. Glahn

School of Medicine Publications

Background

Psychiatric comorbidity is common among individuals with addictive disorders, with patients frequently suffering from anxiety disorders. While the genetic architecture of comorbid addictive and anxiety disorders remains unclear, elucidating the genes involved could provide important insights into the underlying etiology.

Methods

Here we examine a sample of 1284 Mexican-Americans from randomly selected extended pedigrees. Variance decomposition methods were used to examine the role of genetics in addiction phenotypes (lifetime history of alcohol dependence, drug dependence or chronic smoking) and various forms of clinically relevant anxiety. Genome-wide univariate and bivariate linkage scans were conducted to localize the chromosomal regions influencing …

Preterm Birth And Air Pollution: Critical Windows Of Exposure For Women With Asthma, Pauline Mendola, Maeve Wallace, Beom Seuk Hwang, Danping Liu, Candace Robledo, Tuija Männistö

School of Medicine Publications

Background: Ambient air pollutants may increase preterm birth (PTB) risk, but critical exposure windows are uncertain. The interaction of asthma and pollutant exposure is rarely studied.

Objective: We sought to assess the interaction of maternal asthma and air pollutant exposures in relation to PTB risk.

Methods: Electronic medical records for 223,502 US deliveries were linked with modified Community Multiscale Air Quality model outputs. Logistic regression with generalized estimating equations estimated the odds ratio and 95% CIs for PTB on the basis of the interaction of maternal asthma and particulate matter with aerodynamic diameter of less than 2.5 microns and particulate …

Reproductive Health Knowledge Among African American Women Enrolled In A Clinic-Based Randomized Controlled Trial To Reduce Psychosocial And Behavioral Risk, Project Dc-Hope, Uba Backonja, Candace Robledo, Maeve Wallace, Katrina F. Flores, Michele Kiely

School of Medicine Publications

Background: Washington, DC, has among the highest rates of sexually transmitted infections and unintended pregnancy in the United States. Increasing women's reproductive health knowledge may help to address these reproductive health issues. This analysis assessed whether high-risk pregnant African American women in Washington, DC, who participated in an intervention to reduce behavioral and psychosocial risks had greater reproductive health knowledge than women receiving usual care.

Methods: Project DC-HOPE was a randomized, controlled trial that included pregnant African American women in Washington, DC, recruited during prenatal care (PNC). Women in the intervention group were provided reproductive health education and received tailored …

Social Media And Perceptions Of Sexual Consent: Development And Psychometric Assessment Of Two Consent Measures, Kelley Rhoads

Graduate Theses and Dissertations

Background. Preliminary qualitative research suggests some college students believe sexual consent can be communicated and interpreted in Social settings, such as parties or bars, and in contexts lacking face-to-face interaction like text messages and Social media content. Previous sexual consent researchers have described perceptions of consent that occur in Social settings as “outside the bedroom” consent. The belief that sexual consent can be interpreted from Social media content or that accepting an alcoholic beverage from someone at a bar is indicative of sexual consent is problematic and warrants further study. Current validated consent scales are limited and do not assess …

Young Adult E-Cigarette Exposure: Implications For Policy And Prevention, Monica Page Daniel Dobbs

Graduate Theses and Dissertations

Objective. The purpose of this study is to examine factors associated with e-cigarette use among college students to better understand their behavior. Using Ajzen’s Reasoned Action Approach, this study sought to better understanding the influence of attitudes, Social norms, and perceived behavioral controls (PBCs) on college students’ intention to try e-cigarettes (even one puff) in the next 30 days.

Methodology. This study employed three phases for a mixed methods design that took place between December 2015 and April 2016. Phase 1 used Middlestadt’s salient belief elicitation procedure to capture responses through an open ended survey (n=58). Phase 2, a pilot …

The Influence Of Strength-Training Exercises On The Functional Fitness In Older Adults, Susie Engle

Graduate Theses and Dissertations

The purpose of this study was to examine the influence of strength-training exercises on the functional fitness in older adults. The original convenience sample consisted of 658 participants who attended group strength-training classes offered through the Cooperative Extension Service. The Senior Fitness Test was used to assess baseline fitness levels at the beginning and end of the 12-week strength-training program. Data was collected from 2008 to 2015. Of the 658 participants, 110 were aged 60 to 94 and presented posttest scores occurring approximately 12 weeks after pretest dates. Of the 110 subjects, 99 were female and 11 were male. The …

Investigation Of Cnt-Induced Escherichia Coli Lysis And Protein Release, Abdollah Mosleh

Graduate Theses and Dissertations

This research investigated the use of carbon nanotubes (CNTs) as a treatment to increase the permeability of a bacterial cell wall. Recombinant Escherichia coli BL21 (DE3) containing a plasmid that expressed Green Fluorescent Protein (GFP) and -lactamase were exposed to CNTs under various levels of agitation for different times. Fluorescence assay for GFP, optical absorbance for -lactamase activity, and Transmission Electron Microscopy (TEM) were used to determine the amount of released protein, and visually examine the permeability enhancement of the cells, respectively. It was found that more -lactamase was present in the culture fluid after treatment with CNTs in a …

Fuzzy Logic In Health Care Settings: Moral Math For Value-Laden Choices, Sarah Voss

Journal of Humanistic Mathematics

This essay is intended as an example of “moral math”, i.e., ideas culled from mathematics which can positively impact social behavior. Specifically, it combines fuzzy logic with the ethical decisions which hospital staff and others are sometimes forced to make about health care (e.g., euthanasia issues following Hurricane Katrina). The assumption is that such decisions involve value-laden choices which lend themselves to “fuzzy” or “smart” protocols. The article discusses the history of fuzzy logic – what it is, how it is used, and how it might be even better-used as a support basis for making difficult choices …

Medical School Watercooler Newsletter - July 31, 2016, Lindsey Lyle

Watercooler Newsletter

This is the July 31, 2016 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• COM Class of 2020 Introduced to Medical School During Orientation
• Med School Café - Expert Advice for the Community
• 43rd Annual Research Day Features Keynote Speaker, Medical Student Research Presentations
• Dr. Kevin Green Featured on FOX10
• USA Graduate Student Publishes Article in The Journal of Immunology

Knowledge, Perceptions, And Attitudes Of Certified Registered Nurse Anesthetists Regarding The Use Of Desflurane With A Laryngeal Mask Airway, Rachel Davidson

Doctoral Projects

Abstract

The purpose of this capstone project is to evaluate the knowledge, perceptions, and attitudes of currently practicing, nationally board certified, registered nurse anesthetists regarding the use of desflurane with laryngeal mask airways. This research was conducted by developing a questionnaire and administering it to current nurse anesthetists. A literature review was completed to establish a theoretical framework, summarize and describe the current state of science, and determine the nature and design of this study. Although there are studies regarding desflurane use during the maintenance of general anesthesia using a laryngeal mask airway, there is no current perception-based research regarding …

Intimate Partner Violence: The Best Of Primary Prevention Strategies, Sarah Roberts

Student Works

This workshop series is designed as a tool to help prevent the pervasive issue of Intimate Partner Violence. The individual workshops focus on the promotion of empowerment, positive communication, gender equality and on building relationship skills between men and women. They also provide opportunities for participants to examine their values and attitudes towards gender and relationships, to build on their knowledge on aspects of sexuality and to develop skills to help them communicate with others and ensure that they are communicating what they desire. The workshops are based on participatory learning approaches as research demonstrates that this method is more …

Moderation Analysis Of Bowel Function Among Nutrients And Physical Function Or Depression, As Well As Whether Bowel Function Is Related To Cognition In Older Adults, Jessie Alwerdt

USF Tampa Graduate Theses and Dissertations

As we age, the risk for gut issues, such as smooth muscle tone, may be an underlying indirect or direct cause or risk factor for many age-related issues, such as frailty. Consequences of decreased motility and depleted epithelial barrier may result in nutrient deficiencies that may increase the risk for malnutrition (Brownie, 2006). Further, there is increasing evidence that there is a gut-brain-axis relationship that may influence cognition and mental health issues, such as depression and anxiety. While there are relationships established, the interconnections of these factors have yet to be fully understood.

This dissertation examined several relationships specific to …

Assessing Spanish-Speaking Children: A Comparison Of International Practices, Alexis Decker

Honors Projects

According to The National Center for Educational Statistics, 7.7% of all public K-12 students in the United States (US) speak Spanish in the home, representing 76.5% of all English- language learner (ELL) students (2013). Children exposed to two languages are referred to in the literature as ELLs, language minorities and/or bilingual children. As these children enter school, language disorders and differences may become apparent to the Speech-Language Pathologist (SLP). It is the responsibility of the SLP to determine whether a disorder exists or if what is being observed is simply an issue of language difference. As such, it is important …

Hypoxic Pulmonary Vasoconstriction, Miranda Shull

Nursing Student Class Projects (Formerly MSN)

A poster project about Hypoxic Pulmonary Vasoconstriction.

Perceptions Of Reversible And Permanent Contraception In India, Neha Rani Bhardwaj

Biomedical Sciences ETDs

Background: In 1951 India became the first country to launch a national family planning program focused on promoting reversible and permanent contraception including financial incentives for both method acceptors and providers. Despite governmental provision of the copper intrauterine device (IUD), oral contraceptive pills (OCP) and condoms at no cost, most Indian women choose permanent sterilization after completing childbearing. Whether the predominance of sterilization stemmed from Indian men and women’s desire for permanent contraception, from deficient knowledge and access to reversible methods, from public health messages and established norms, or from coercion in the form of incentives is unknown. Objectives: The …

An Analysis Of The Implementation Of The Policy To Integrate Of National Defense Components In Managing Non-Military Threats In The Health Sector, Sugeng Winarno, Prastuti Soewondo

Journal of Indonesian Health Policy and Administration

This research was based on the Minister of Defense’s Decree No. 16/2012 that stated that all national defense components to integrate into one unit when they encounter military and non-military threats. The Ministry of Health, as the main player, and other governmental and private agencies would also play a role in overcoming complex and multidimensional non-military threats, especially in the health sector. Among those threats are infectious diseases such as HIV/AIDS and Ebola. We aim to discover the implementation process of the law above in the management of those two diseases. This was a qualitative analytical research with in-depth interviews. …

Policy Implementation Of Health Coverage For Indonesian Migrant Workers, Risky Kusuma Hartono, Budi Hidayat, Pujiyanto Pujiyanto

Journal of Indonesian Health Policy and Administration

The purpose of this research is to analyze the policy implementation of health coverage for TKI. This research uses a qualitative method with in-depth interview. The framework of this research consists of the aspect of the advisable policy, the implementation factors, and the schematic representation of the problem by using SWOT. The result of this research is the health insurance owned by TKI comes from TKI insurance, the membership of JKN, and insurance during their employment abroad. TKI insurance policy is the instruction of Law No. 39 of 2004 which regulates the obligation of the ownership of the social security …

Study On Public Health Financing In Pidie Jaya District In 2013, Hanifah Hasnur, Purnawan Junadi

Journal of Indonesian Health Policy and Administration

Albeit high dependency on central government transfer (around 69% of total health expenditure), funding from local PAD has been increasing. The revenue shall support priority health programs. This study aims to analyze local health financing system and as input for health program planning. Health financing portrait how fund being spent, and identfying who the agents are as well as the beneficiaries. The study shows spending on health from local budget is Rp130,000. Expenditures on operational costs for direct activities and community-based health efforts or Upaya Kesehatan Masyarakat (UKM) are still low (41%). Puskesmas needs to do more health-related activities for …

Rhabdomyolysis- Diagnosis And Treatment, Ngonidzashe Chifamba

Nursing Student Class Projects (Formerly MSN)

Rhabdomyolysis is the dissolution of skeletal muscle caused by injury to skeletal muscle. It is a direct result of leakage of toxic cellular content into the blood stream. The most common cause of rhabdomyolysis is drug use, trauma, immobility, medicines and intense muscular exercise. The classic triad of rhabdomyolysis symptoms comprises the following symptoms; myalgias, generalized weakness and darkened urine. Pathophysiology of rhabdomyolysis involves an increase in free ionized calcium and sodium which draws water into the cell and disrupts the integrity of the intracellular milieu. Rhabdomyolysis can be life-threatening and disabling, having a clinician who knows how the syndrome …

Human Papilloma Virus-Related Cervical Dysplasia, Shaylyn D. Webster

Nursing Student Class Projects (Formerly MSN)

Among sexually active men and women, the human papilloma virus (HPV) is one of the most common sexually transmitted infections. With more than 200 different genotypes of HPV known, there are more than 500,000 cases each year in the United States alone (Lowy, 2016). The virus is associated with nearly all cervical cancers, anal cancers, vaginal cancers, penile cancers, and head and neck cancers (Jorge & Wright, 2016). In women, the virus is capable of causing slow cellular changes on the cervix, and this dysplasia is graded based on severity (Jorge & Wright, 2016).

The statistics related to the prevalence …

Admission Floor And Its Relation To Length Of Stay In Patients With Hip Fracture, Jacob Rust, Thomas Kwarcinski, Cathyann Feher Rn,Msn, Michael D. Pasquale Md, Facs, Fccm

USF-LVHN SELECT

No abstract provided.

Comparison Of In-Line Versus Conventional Independent Continuous Renal Replacement Therapy In Extracorporeal Membrane Oxygenation Patients, Nicole Stansbury, Taryn Samet Md, Timothy S. Misselbeck, James K. Wu Md

Research Scholars Poster Presentation

No abstract provided.

Randomized Controlled Trials: Who Fails Run-In?, Judy R. Rees, Leila A. Mott, Elizabeth L. Barry, John A. Baron, Jane C. Figueiredo, Douglas J. Robertson, Robert S. Bresalier, Janet L. Peacock

Dartmouth Scholarship

Background: Early identification of participants at risk of run-in failure (RIF) may present opportunities to improve trial efficiency and generalizability. Methods: We conducted a partial factorial-design, randomized, controlled trial of calcium and vitamin D to prevent colorectal adenoma recurrence at 11 centers in the United States. At baseline, participants completed two self-administered questionnaires (SAQs) and a questionnaire administered by staff. Participants in the full factorial randomization (calcium, vitamin D, both, or neither) received a placebo during a 3-month single-blinded run-in; women electing to take calcium enrolled in a two-group randomization (calcium with vitamin D, or calcium alone) and received calcium …

Development Of A Novel Ex Vivo Equine Corneal Model, Todd L. Marlo, Elizabeth A. Giuliano, Ajay Sharma, Rajiv R. Mohan

Pharmacy Faculty Articles and Research

Objective

To develop an ex vivo equine corneal organ culture model. Specifically, to assess the equine cornea's extracellular matrix and cellularity after 7 days using two different culture techniques: either (i) immersion system or (ii) air/liquid interface system, to determine the best ex vivo equine corneal model.

Animals Studied

Fourteen healthy equine corneas of various breeds.

Procedures

Equine corneas with 2 mm of perilimbal sclera were freshly harvested from 7 horses undergoing humane euthanasia. One corneal–scleral ring (CSR) from each horse was randomly placed in the (i) immersion condition organ culture system (IC), with the contralateral CSR being placed in …

Use Of Distance Delivery Interventions (Web-Based, Mhealth, Telehealth) For Hard-To-Reach, Vulnerable Midlife And Older Individuals, Patricia A. Hageman

Posters and Presentations: Physical Therapy

As older adults may lack access to professional services and/or have limited transportation to seek care, the increasing availability of technologies for self-monitoring, safety, and/or preventive or therapeutic management may show promise for reaching vulnerable older adults. This presentation will describe several types of distance delivery platforms, such as web-based, mHealth, and/or telehealth, which may have applications to older adults in arenas of education, clinical practice or research. This session will highlight the benefits and limitations of these technologies, and will summarize current research about the effectiveness of using these technologies with midlife and older individuals.

Objectives:

1. Identify benefits and …

Safe Discharge: Perception Among Both Emergency Medicine Attending Physicians And Nurses Regarding Discharging Patients After Opiate Or Opioid Administration, Benjamin Croll

USF-LVHN SELECT

No abstract provided.

Intensive Behavioral Therapy For The Treatment Of Obesity In The Elderly, Shabaaz Sandhu, Elaine Banerjee Md, Mph, Robin S. Schroeder Md

USF-LVHN SELECT

No abstract provided.

Adapting To Hospital Culture And Improving Patient Care: Development Of A Pediatric Gastronomy Tube Medical Program, Heather Geist Bs, Marybeth Browne Md

USF-LVHN SELECT

No abstract provided.