Medicine and Health Sciences Commons^™

Relationship Between Chronic Disease Conditions And Colorectal Cancer Screening: Results From The 2012 National Health Interview Survey Data, Daniel Owusu, Joshua Longcoy, Megan Quinn, Ke-Shang Wang

ETSU Faculty Works

Background: Uptake of screening remains crucial in the prevention of both the incidence of colorectal cancer (CRC) and its mortality.

Objectives: To estimate the prevalence of CRC screening and identify chronic conditions that predict CRC screening uptake among US adults using the 2012 National Health Interview Survey (NHIS) data.

Materials and Methods: A cross-sectional analysis of the 2012 NHIS data. Chronic conditions examined were hypertension, cancer history, arthritis, ulcer, and high cholesterol level. A total of 21,511 participants were included in the analysis. Weighted univariate and multiple logistic regression analyses in SAS ver. 9.2 were used to estimate the …

The Pediatric Pt Management Of A Survivor Of Cancer: A Case Report, Kaylene Samuels

Case Report Posters

Cancer in the cerebellum in a pediatric population is rare. The cerebellum is responsible for: coordination of ongoing movements, postural control, visual gaze, performing smooth purposeful movements. There is limited evidence investigating the physical therapy management of pediatric survivors of cancer, more specifically, in cerebellum brain tumors. The purpose of this case report was to investigate the PT management of a pediatric survivor of cancer who had a cerebellar tumor resection.

Physical Therapy Management Of An In-Patient After Total Knee Arthroplasty: A Case Report, Jareth Pamer

Case Report Posters

Background: Increasing prevalence of knee OA and TKA; according to the American Academy of Orthopedic Surgeons, there will have been a half a million TKA procedures performed by 2030. Purpose: The purpose of this case report is to describe the physical therapy management of an in-patient status post total knee arthroplasty.

Inpatient Physical Therapy For A Patient With Dementia After Right Above Knee Amputation: A Case Report, Benjamin Blanchette

Case Report Posters

Background: Lower limb amputation is a traumatic procedure that is most commonly performed on individuals who are diabetic or have peripheral vascular disease. Other causes of amputation include infection, trauma or cancer. A sarcoma is a cancer in tissues such as muscle, fat, cartilage, or bone. The treatment goal is to excise and prevent growth or metastasis of the sarcoma. There is limited literature regarding dementia involving motor planning deficits and physical therapy. However, based upon the interventions provided by physical therapists it is believed that individuals with dementia involving motor planning deficits will have some difficulty. Purpose: The purpose …

The Use Of Parkinson’S Disease Specific Rehabilitative Interventions To Treat A Patient With Lewy Body Dementia: A Case Report, Cassandra Dawley

Case Report Posters

Background: Lewy Body Dementia (LBD), and the role of physical therapy (PT) in treating this population, is scarce in the literature. LBD is considered a differential diagnosis of Parkinson’s Disease (PD); therefore, the idea to use PD specific interventions, primarily Lee Silverman Voice Treatment-Big (LSVT BIG), may be considered a suitable intervention. Purpose: To educate the readers about LBD, how it presents, and how PD related interventions can be used as a treatment.

Medical School Watercooler Newsletter - November 23, 2014, Lindsey Lyle

Watercooler Newsletter

This is the November 23, 2014 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• 10 Tips for a Healthy Thanksgiving
• Dr. Michael Welsh Gives 2014 Baugh Lecture
• USA Medical Students Host Mobile Mental Health Outreach Event
• December Med School Café - 'Multiple Sclerosis: A Simple Message About a Complicated Disease'

Outpatient Physical Therapy Management Of A Female Athlete With A Left Anterior Cruciate Ligament Reconstruction And Left Medial Meniscectomy: A Case Report, Kyle Brown

Case Report Posters

Background: The anterior cruciate ligament (ACL) is a structure within the knee that prevents anterior translation of the tibia on the femur as well as checks lateral rotation of the tibia and extension of the knee. The ACL is typically injured in noncontact sports by a sudden deceleration prior to a change of direction or landing motion. Female athletes are more than twice as likely to sustain an injury to the ACL. An ACL injury is often accompanied by an injury to the meniscus of the same knee. Purpose: The purpose of this case report is to provide a comprehensive …

The Effects Of Robot-Assisted Gait Training And Task-Specific Training On Adl Function And Mobility For A Patient After A Stroke: A Case Report, Maegen Johnson

Case Report Posters

Background: Stroke is the fourth leading cause of death and the leading cause of long term disability in the United States. Repetitive task-specific training has been shown to be favorable in stroke rehabilitation. Robot-assisted gait training (RAGT) incorporates gait training and repetitive task-specific training. RAGT has been shown to increase the likeliness of independent walking ability in patients who have experienced a stroke, especially when utilized in first three months. Currently there is limited research regarding the impact of RAGT on ADL function. Purpose: To describe the impact of robot-assisted gait training in combination with task-specific training on the functional …

Multimodal Physical Therapy Interventions Designed To Restore Independence And Motor Control In A Patient With Acute Cerebellar Stroke, Annarae Andresen

Case Report Posters

Background: The cerebellum integrates sensory perception, coordination, and motor control. Cerebellar stroke accounts for 3.4% of the 600,000 strokes that occur annually in the United States. Due to the rarity of ACS, very little research has been conducted regarding multimodal PT interventions as a treatment option. Purpose: The purpose of this case report was to describe multimodal PT interventions designed to restore independence and motor control for a patient with ACS.

Student Training In A University Setting Voice Clinic- How Do We Do It?, Chaya D. Nanjundeswaran (Guntupalli), Celia Bassich, Robin Samlan

ETSU Faculty Works

This presentation will discuss the challenges that clinical supervisors face when trying to balance efficient graduate student training and patient welfare in university voice clinics. We will propose a model in which we seek to balance the needs of the patient, student clinician, and clinical instructor.

Outpatient Physical Therapy Following Triple Arthrodesis Surgery: A Case Report, Nella Bernardoni

Case Report Posters

Background: Triple arthrodesis is the surgical fusion of the talonavicular, talocalcaneal, and calcaneocuboid joints of the foot. Joint surface preparation includes debridement, removal of cartilage, burring of subchondral bone, and fish scaling of the joint surfaces. The joints are then fused using screws. No inversion or eversion motion, only plantarflexion and dorsiflexion. Primary goals: abolish pain, correct underlying deformities, and restore a stable platform for ambulation. Indicated for severe arthritis, instability, and deformity that cannot be controlled with nonsurgical approaches. Purpose: To provide an overview of triple arthrodesis surgery and to report a case describing the specific outpatient physical therapy …

Anti-Gravity Treadmill And Functional Training For An Army Soldier Following A Femoroplasty And Labral Repair: A Case Report, Christopher Halloran

Case Report Posters

Background/Purpose: Femoral Acetabular Impingement (FAI) is characterized by three specific types of impingement between the head of the femur and acetabulum. Cam impingement occurs when the head of the femur is abnormally shaped. The head of the femur isn’t round, it is more of a pistol grip shape. It's even referred to as a pistol grip deformity. Due to this abnormal shape, the head of the femur cannot move properly in the anatomically designed ball-and-socket joint. The result is a shearing force on the labrum and the articular cartilage. Minimal amounts of articles were found that truly utilized physical therapy …

Outpatient Physical Therapy Management Of A Breast Cancer Survivor Following Kyphoplasty With A Complex Medical History, Molly Thornton

Case Report Posters

Background and Purpose: There are over 3 million breast cancer survivors in the U.S. Cancer and its treatment can cause a wide variety of long-term physical and psychological problems. The physical therapist’s role is not well defined for this population. The purpose of this case report is to describe the outpatient physical therapy management for a patient with a history of breast cancer as well as considerable additional health issues.

Physical Therapy Outcomes In A 28 Year Old Male With A Femoral Neck Fracture Using Aquatic And Land-Based Therapeutic Exercise: A Case Study, Daniel Johnson

Case Report Posters

Background: Hip fractures occur in approximately 341,000 persons each year in the U.S. Hip fractures at a young age are uncommon and are usually the result of a high-velocity injury or, rarely, secondary to bone pathology. Morbidity associated with an inability to return to a pre-fracture level of mobility often results in a loss of independence, reduction in quality of life, and depression. There is a lack of available literature on the physical therapy management of hip fractures in the younger patient population. Purpose: The purpose of this case report was to investigate the physical therapy management of a 28 …

Evaluating Residents' Self-Assessment Skills Through Triangulation With Faculty And Patient Feedback, Drew Keister Md, Susan E. Hansen Ma, Julie Dostal Md

Department of Family Medicine

No abstract provided.

Analysis For Co-Occurring Sequence Features Identifies Link Between Common Synonymous Variant And An Early-Terminated Npc1 Isoform, Mercedeh Movassagh, Prakriti Mudvari, Maria Kokkinaki, Nathan J. Edwards, Nady Golestaneh, Anelia Horvath

Pharmacology and Physiology Faculty Publications

Direct assessment of allelic phase for DNA and RNA features of diploid genomes has been challenging for Sanger sequencing, due to its allele-conflating base-calling signal. Massively parallel sequencing technologies are based on the generation of a continuous copy of a single strand sequence segments, thus preserving the allelic relation between the features of the original molecules. We have performed a transcriptome-wide search for co-occurrence of variant nucleotides and exon-intron boundaries positioned within the length of a single sequencing read. Analysis of 75 human transcriptomes from retinal pigment epithelia (RPE), glioblastoma, low-grade brain tumor, breast cancer and colon cancer, have identified …

Clinician Reported Barriers To Diabetes Group Visits, Beth Careyva Md, Melanie B. Johnson Mpa, Kyle Shaak Bs, Brian Stello Md

Department of Family Medicine

No abstract provided.

Patients With Disabilities As Teachers (P-Dat): Do Participants Retain What Is Taught And Is It Relevant To Practice?, Susan E. Hansen Ma, Sweety Jain Md

Department of Family Medicine

No abstract provided.

Innovations To Improve Access To Primary Health Care For Vulnerable Populations: Results From An Environmental Scan Using A Social Media Approach, Lauralie Richard Phd, Jane M. Gunn Mbbs, Phd Fracgp, John Furler Fracgp, Mbbs, Phd, Benjamin F. Crabtree Phd, Jeannie Haggerty Phd, Pierre Pluye Md, Phd, William L. Miller Md, Ma, Jean-Frédéric Levesque Md, Phd, Frcp, Grant M. Russell Mbbs, Phd, Fracgp

Department of Family Medicine

No abstract provided.

Effects Of Step-Wise Increases In Dietary Carbohydrate On Circulating Saturated Fatty Acids And Palmitoleic Acid In Adults With Metabolic Syndrome, Brittanie M. Volk, Laura J. Kunces, Daniel J. Frieidenreich, Brian R. Kupchak, Catherine Saenz, Juan C. Artistizabal, Maria Luz Fernandez, Richard S. Bruno, Carl M. Maresh, William J. Kraemer, Stephen D. Phinney, Jeff S. Volek

College of Science & Mathematics Departmental Research

Recent meta-analyses have found no association between heart disease and dietary saturated fat; however, higher proportions of plasma saturated fatty acids (SFA) predict greater risk for developing type-2 diabetes and heart disease. These observations suggest a disconnect between dietary saturated fat and plasma SFA, but few controlled feeding studies have specifically examined how varying saturated fat intake across a broad range affects circulating SFA levels. Sixteen adults with metabolic syndrome (age 44.9±9.9 yr, BMI 37.9±6.3 kg/m2) were fed six 3-wk diets that progressively increased carbohydrate (from 47 to 346 g/day) with concomitant decreases in total and saturated fat. Despite a …

Nucleoside Reverse Transcriptase Inhibitors Possess Intrinsic Anti-Inflammatory Activity, Benjamin J. Fowler, Bradley D. Gelfand, Younghee Kim, Nagaraj Kerur, Valeria Tarallo, Yoshio Hirano, Shoba Amarnath, Daniel H. Fowler, Marta Radwan, Mark T. Young, Keir Pittman, Paul Kubes, Hitesh Agarwal, Keykavous Parang, David R. Hinton, Ana Bastos-Carvalho, Shengjian Li, Testuhiro Yasuma, Takeshi Mizutani, Reo Yasuma, Charles Wright, Jayakrishna Ambati

Pharmacy Faculty Articles and Research

Nucleoside reverse transcriptase inhibitors (NRTIs) are mainstay therapeutics for HIV that block retrovirus replication. Alu (an endogenous retroelement that also requires reverse transcriptase for its life cycle)–derived RNAs activate P2X7 and the NLRP3 inflammasome to cause cell death of the retinal pigment epithelium in geographic atrophy, a type of age-related macular degeneration. We found that NRTIs inhibit P2X7-mediated NLRP3 inflammasome activation independent of reverse transcriptase inhibition. Multiple approved and clinically relevant NRTIs prevented caspase-1 activation, the effector of the NLRP3 inflammasome, induced by Alu RNA. NRTIs were efficacious in mouse models of geographic atrophy, choroidal neovascularization, graft-versus-host disease, and sterile …

Effects Of Audience Presence On Running Performance, Lane Thielemier

Student Theses and Dissertations

The effect an audience has on performance has received a wave of attention in past years. Social facilitation studies suggest that when people are in the presence of an audience, whether interacting or not, they will perform at higher levels if the task is familiar to them. Furthermore, these studies have found that when a task is unfamiliar to the individual performance will be inhibited. Seventeen males underwent a study to test their running performance in which they ran for twelve minutes on a treadmill in three different variable settings. Results revealed that there was no significant difference in distance …

Development Of Metalinguistic Awareness: Evidence From Children’S Overt Productions, Laura Kirkby, Mallory Dingess, Jamesa Ewing, Whitney Salvers, Kerry Proctor-Williams

ETSU Faculty Works

This study examined whether metalinguistic frequency increases or utterance type changes with age in children with typical language. Overt metalinguistic productions of 32 children, 3;0-5;7, were collected during recast intervention. Overall, the data showed changes in frequency and proportion of types with age.

Role Of Host Micrornas In Kaposi's Sarcoma-Associated Herpesvirus Pathogenesis, Zhiqiang Qin, Francesca Peruzzi, Krzysztof Reiss, Lu Dai

School of Medicine Faculty Publications

MicroRNAs (miRNAs) are small non-coding RNA species that can bind to both untranslated and coding regions of target mRNAs, causing their degradation or post-transcriptional modification. Currently, over 2500 miRNAs have been identified in the human genome. Burgeoning evidence suggests that dysregulation of human miRNAs can play a role in the pathogenesis of a variety of diseases, including cancer. In contrast, only a small subset of human miRNAs has been functionally validated in the pathogenesis of oncogenic viruses, in particular, Kaposi's sarcoma-associated herpesvirus (KSHV). KSHV is the etiologic agent of several human cancers, such as primary effusion lymphoma (PEL) and Kaposi's …

Transmedial Documentation For Non-Visual Image Access, Melody J. Mccotter

Proceedings from the Document Academy

In my doctoral studies on information accessibility for the individual who is blind or visually impaired, I’ve been exploring the ways we can make image documents more accessible. This requires using an alternative sensory modality, and translating the document into a different format. The questions that arise when we consider this process are many, but among them are:

• Is it the same document once we’ve converted it to an audio narrative about the work, or a 3D topographic map of an artwork, or a musical interpretation?
• If it is not the same document, how truthful can the “trans-medial” translation be …

Book Review: Questioning Protocol, Barbara Lewis Mba

Patient Experience Journal

In her review of Questioning Protocol by Randi Redmond Oster, Barbara Lewis shares how this new and award winning book takes the reader on Randi Oster's harrowing journey of navigating the healthcare system while helping her teenage son’s battle with Crohn’s disease. Seventeen chapters build a chronological story of success, frustration and failure in dealing with modern medicine and a healthcare industry that may appear foreign to the outsider.

Book Review: The Language Of Caring Guide For Physicians: Communication Essentials For Patient-Centered Care (2nd Edition), Chet Wyman Md

Patient Experience Journal

In thie book review for Wendy Leebov and Carla Rotering’s The Language of Caring Guide for Physicians: Communication Essentials for Patient-Centered Care (2nd edition), the author/reviewer conveys his perspective on the essential value of this publication. He offers his recommendation of this book for anyone who wants to improve their own communication skills and also for physician leaders responsible for initiatives to engage physicians and improve service quality, patient outcomes, and CAHPS scores for a department or organization, noting it is an essential read in today’s healthcare environment.

Learning What High Quality Compassionate Care Means For Cancer Patients And Translating That Into Practice, Fiona Mckenzie, Katherine Joel, Charlotte Williams, Kathy Pritchard-Jones Professor

Patient Experience Journal

In 2010, UCLPartners, a partnership of health care providers and universities in North Central London, began a collaboration with local commissioners that aimed to think about cancer care and diagnosis differently. Understanding that a good patient experience can only be delivered by putting patients first and working together along their journey from symptoms to recovery, we brought clinical leaders together with patients to think about how to improve outcomes for patients, outside institutional barriers. From the very beginning this new network, an integrated cancer system, focused on understanding what mattered most to patients and organising how it worked and how …

Exploring The Impact Of An Interprofessional Care Protocol On The Patient Experience And Outcomes For Seniors With Diabetes, Linda J. Mast Phd, Facmpe, Ateequr Rahman Phd, Diane Bridges Phd, Neil L. Horsley Dpm

Patient Experience Journal

Contemporary healthcare has placed intensified focus on the patient experience. Ultimately the patient experience is influenced by relationships with healthcare providers. In order to make a positive impact on patient outcomes and quality of care, the patient experience must be positive. Interprofessional collaboration is recognized as a key aspect of a culture that fosters patient-centered care and a positive patient experience. This quasi-experimental study explores the impact of interprofessional collaboration to develop a preventive services care protocol for seniors with diabetes. Patients were studied over six months using pre-test and post-test measures. Both quantitative data from clinical outcomes and qualitative …

Hearing The Patient Voice: Using Video Intervention/Prevention Assessment To Understand Teens With Cystic Fibrosis, Susan Horky Lscw, Laura E. Sherman Msw, Julie Polvinen, Michael Rich Md

Patient Experience Journal

This qualitative study asked two questions: 1) How do teens with cystic fibrosis (CF) feel about their treatments; and 2) What factors lead teens to adhere, or not adhere, to treatments. To answer these questions we used an innovative approach (Video Intervention/Prevention Assessment or VIA), to learn about the experiences of teens with CF. We loaned video camcorders to teens with CF and asked them to create visual narratives of their lives. Researchers logged and coded videotapes, identifying themes that arose from the material. A primary theme was “Doctors don’t understand.” Participants also highlighted the value of routines and parental …