Medicine and Health Sciences Commons^™

Oncolog, Volume 59, Number 06, June 2014, Jill Delsigne, Luanne Jorewicz, K. Stuyck

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• New Agents Hold Promise for Patients With Advanced Thyroid Cancer: New agents are expanding treatment options for patients with advanced thyroid cancer-not only the papillary variant but also the less common medullary and differentiated variants of the disease
• Surgical Options for Lymphedema: Lymphedema of the extremities, whether from cancer treatment or other causes, typically is not curable. But advances in surgical techniques are reducing or eliminating symptoms for many patients
• INBRIEF: Intensity-Modulated Radiation Therapy Improves Survival in Head and Neck Cancer Patients/ Research Findings Could Lead to Blood Test for Cancer-Related Gene Defects/ Tumor-Suppressing Protein May Help Predict Survival in …

Psychometric Properties Of The Index Of Relocation Adjustment, Abir K. Bekhet, Jaclene Zauszniewski

College of Nursing Faculty Research and Publications

More and more American older adults are relocating to retirement communities, and they experience challenges in adjusting to new surroundings that may increase their depression and mortality. An instrument not previously tested in the United States, the Index of Relocation Adjustment (IRA), may help in early identification of poor relocation adjustment. This study examined the psychometric properties of the IRA using secondary data from a convenience sample of 104 older adults who relocated to 6 retirement communities in Northeast Ohio. Cronbach’s alpha was .86. The IRA was correlated with measures of positive cognitions (r = .48, p < .01) and relocation controllability (r = …

Importance Of Backfat Thickness To Reproductive Performance In Female Pigs, Atthaporn Roongsitthichai, Padet Tummaruk

The Thai Journal of Veterinary Medicine

Backfat in pigs consists of water, collagen, and lipid. Apart from age, body weight, and number of estrus expression, backfat thickness is one of the significant parameters to consider when selecting female pigs into breeding herds since it dominates a number of reproductive performances, e.g. puberty attainment, total piglets born (TB), and farrowing rate. Besides, backfat is one of the significant sources of hormones related to puberty attainment, such as leptin, insulin-like growth factor-I (IGF-I), and progesterone (P4). Evaluation of backfat thickness is majorly performed by an A-mode ultrasonography at P2 position; it provides more accurate body condition than visual …

Reliability Of Portable Blood Glucose Meters For Using In Small Animal Hospital, Siram Suvarnavibhaja, Poramin Yuennan, Ratanaporn Tangwangwiwat, Aomusa Kuaha, Sirintorn Yibchokeanan

The Thai Journal of Veterinary Medicine

The objective of this study was to compare blood glucose concentrations obtained from two portable blood glucose meters (PBGM), Sure-step™ and Accucheck™, with reference method, glucose oxidase test. Blood samples were collected from dogs consulting in Small Animal Hospital, Chulalongkorn University. A hundred and thirty four blood samples were collected in the study. Blood glucose concentrations were measured by using Sure-step™, Accucheck™ and glucose oxidase method respectively in all samples. The intra-class correlation was determined to evaluate the correlation between each PBGM and glucose oxidase test. The range of the blood glucose concentrations was 31.47 to 347.49 mg/dl. Overall intra-class …

Effects Of Prolonged Oral Intake Of Monosodium Glutamate (Msg) On Body Weight And Its Correlation To Stomach Histopathological Changes In Male Rats, Gamal S. Abd El-Aziz, Magdy O. El-Fark, Sherif M. Hassan, Mohamed H. Badawoud

The Thai Journal of Veterinary Medicine

Monosodium glutamate (MSG) is a food additive found in many commercial food products. The safe use of MSG has generated much controversy regarding weight gain and health effects. In the present study, the effects of MSG administration for different periods of time on weight gain and on the structure of gastric mucosa in rats were investigated. Thirty-two adult male rats were used and randomly divided into two treated and two control groups (n=8, each). The rats in the treated groups received a daily oral dose of 395 mg/kg bw of MSG for 3 and 6 weeks, respectively, while the control …

Efficacy Of Live Infectious Bronchitis Vaccine Programs Against Infection By Qx-Like Strain Of Infectious Bronchitis Virus, Ekasingh Sarueng, Wisanu Wanasawaeng, Jiroj Sasipreeyajan, Niwat Chansiripornchai

The Thai Journal of Veterinary Medicine

The aim of this study was to evaluate the efficacy of live infectious bronchitis (IB) vaccine programs against infection by a QX-like strain of the IB virus isolated in Thailand. The experimental groups were divided into 5 groups. Group 1 broilers were administered with Poulvac IB QX-like at 1 day old. Group 2 broilers were administered with Poulvac IB QX-like at 1 and 14 days old. Group 3 broilers were administered with Nobilis IB H120 and Poulvac IB QX-like at 1 and 14 days old, respectively. Group 4 broilers were administered with Nobilis IB H120 and Nobilis IB 4-91 at …

Phenotypic Characterizations And Genetic Study Of Progressive Rod-Cone Degeneration In Poodles In Thailand, Metita Sussadee, Janjira Phavaphutanon, Chaiyan Kasorndorkbua, Areerat Kongcharoen, Preenun Jitasombuti, Sudtisa Laopiem, Aree Thayananuphat

The Thai Journal of Veterinary Medicine

Progressive rod-cone degeneration (PRCD) is one of several groups of inherited progressive retinal atrophy in dogs. This study aims to describe the characterization of phenotypic appearance and demonstrate the responsible gene mutation, including analysis of the allele frequency of PRCD in Poodle dogs in Thailand. All 10 Poodles with clinical signs of PRCD were identified by a history of progressive vision loss, an abnormal obstacle test, and fundic appearance. Genetic testing of PRCD gene mutation using the Polymerase Chain Reaction and Restriction Fragment Length Polymorphism technique was performed in all dogs. The result confirmed that all 10 dogs were affected. …

The Effectiveness Of Vaccination With Two Live Infectious Bronchitis Vaccine Strains Against Qx-Like Infectious Bronchitis Virus Isolated In Thailand, Tawatchai Pohuang, Niwat Chansiripornchai, Achara Tawatsin, Jiroj Sasipreeyajan

The Thai Journal of Veterinary Medicine

The purpose of this study was to evaluate the level of protection generated by vaccination with 2 live attenuated vaccine strains against QX-like infectious bronchitis virus (IBV) isolated in Thailand. Eighty-four 1-day-old broiler chickens were randomly allocated into 6 groups with 14 chickens in each group. Groups 1-4 were vaccinated with different vaccination programs against IBV. Groups 5 and 6 did not receive any IBV vaccine and served as positive and negative control groups, respectively. At 1 day old, the chickens in groups 1 and 4 were vaccinated with H120 vaccine whereas the chickens in groups 2 and 3 were …

Efficacy Of Fenbendazole Against Ascaridia Spp. In Large Macaws, Thawat Lekdumrongsak, Sonthaya Tiawsirisup, Wijit Banlunara, Funknathee Prapasawat, Monchanok Pussayanawin, Nicha Prommatha, Suttipong Suttiyaporn

The Thai Journal of Veterinary Medicine

Ascarids are common endoparasites in psittacines. Fenbendazole has been reported for treatment of ascarid infection in many avian species. In this study, the efficacy of fenbendazole against Ascaridia spp. in large macaws was evaluated. Seventeen pairs of naturally infected large macaws were divided into 3 groups. Birds in group 1 (6 pairs) were treated with fenbendazole per os at 35 mg/kg and repeatedly on day 10. Birds in group 2 (5 pairs) were treated with fenbendazole mixed in feed at 35 mg/kg and repeatedly on day 10. Birds in group 3 (6 pairs) served as untreated control group. Ascarid eggs …

Pancreas Morphology And Duct System Of Swamp Buffaloes (Bubalus Bubalis), Tilladit Rung-Ruangkijkrai, Wuthichai Klomkleaw

The Thai Journal of Veterinary Medicine

Swamp buffaloes have been important to Thai countryfolk for centuries. However, it’s meat consumption has increased continuously. Since meat and offal of cattle are very similar, pancreas might be used to differentiate buffalo offal from cow offal. Pancreases from 10 adult buffaloes of both sexes were obtained and studied anatomically. Studies revealed that, unlike human and other animals, buffalo pancreas had a unique F-shape with left lobe, right lobe, body, and uncinate process. There was no main pancreatic duct. Only one accessory pancreatic duct was found open into minor duodenal papilla similar to those of cow. Furthermore, unlike human and …

The Salience And Perceptual Weight Of Secondary Acoustic Cues For Fricative Identification In Normal Hearing Adults, Derek Petti

Dissertations, Theses, and Capstone Projects

The primary cue used by normal hearing individuals for identification of the fricatives /s/ and /ʃ/ is the most prominent spectrum of frication, which is discrete for this fricative contrast. Secondary cues that influence the identification and discrimination of these fricatives are context dependent. Specifically, the secondary cues that have been found to most significantly impact fricative perception include (a) the second formant transition onset and offset frequencies of a fricative-vowel pair, and (b) the amplitude of the spectral peak in the 2500Hz region of frication relative to an adjacent vowel’s peak amplitude in the same frequency region. However, the …

Ecg Quiz, Chollada Buranakarl, Thanusorn Phakhawambodee, Rampaipat Tungjitpeanpong, Pakit Boonpala

The Thai Journal of Veterinary Medicine

No abstract provided.

Antiviral Activity Of Four Commercial Tilmicosin Preparations Against Porcine Reproductive And Respiratory Syndrome Virus (Prrsv): An In Vitro Study, Korakrit Poonsuk, Jirapat Arunorat, Yonlayong Woonwong, Panchan Sitthicharoenchai, Suphattra Jittimanee, Porjit Choojai, Roongroje Thanawongnuwech

The Thai Journal of Veterinary Medicine

The efficacy of four commercial tilmicosin preparations (A, B, C and D) against type 2 porcine reproductive and respiratory syndrome virus (PRRSV), 01NP1 (Thai isolate), infection in cultured pulmonary alveolar macrophages (PAMs) was conducted in vitro. Primary PAMs were collected from four 4-week-old PRRSV-free pigs. After separately plated onto four 24-well plates, PAMs were treated separately by 4 commercial tilmicosin preparations of 2 concentrations each (0.1 mg/ml and 0.01 mg/ml). The treated PAMs were inoculated with 0.05 MOI of 01NP1 strain and were stained with PRRSV specific antibody using immunoperoxidase monolayer assay (IPMA) to evaluate the quantity of PRRSV infected …

Normal Electroretinogram In Domestic Shorthair Cats Using A Short Protocol Of Hmserg, Metita Sussadee, Janjira Phavaphutanon, Kanthapan Ubolrat, Aree Thayananuphat

The Thai Journal of Veterinary Medicine

This study aimed to determine normal electroretinogram (ERG) parameters in healthy domestic shorthair (DSH) cats. Normal ERG in seventeen DSH cats was recorded using the QuickRetCheck protocol, a very short method to assess retinal function, of the Handheld Multispecies eletroretinography (HMsERG). Scotopic ERGs were recorded in cats under tiletamine-zolazepam and isoflurane anesthesia. At low light intensity (10 mcd.s/m2) stimulation which determined the rod photoreceptor function, a-wave could not be detectable while the mean±standard error of b-wave amplitude and implicit time were 96.26 ± 5.98 μV and 64.66 ± 0.83 msec, respectively. At standard light intensity (3,000 mcd.s/m2), the mean a-wave …

Cloning And Sequence Analysis Of Orf5 Gene Of Porcine Reproductive And Respiratory Syndrome Virus Of The Zj Strain, Baocheng Hao, Dengyuan Niu, Xiaoyong Xing, Haitao Xiang, Fengqin Wen, Xiaoping Fu, Jianping Liang, Yonghao Hu

The Thai Journal of Veterinary Medicine

A pair of the special primers was designed and synthesized according to the ORF5 sequence of porcine reproductive and respiratory syndrome virus (PRRSV), which was published in GenBank. In 2009 a pig farm in Zhejiang province suspected some diseased and dead pigs displaying symptoms of porcine reproductive and respiratory syndrome and provided 12 samples (spleen, kidney or lymph nodes) for laboratory diagnosis. The samples were positive of porcine reproductive and respiratory syndrome by PCR. The ORF5 gene was amplified by RT-PCR and cloned into pMD-18T vector. Nucleotide sequence was determined by sequencing and compared with other ORF5 genes in GenBank. …

Ultrasound Diagnosis, Phiwipha Kamonrat

The Thai Journal of Veterinary Medicine

No abstract provided.

Biophysical Characterization Of The First Four Metal-Binding Domains Of Human Wilson Disease Protein, Alia V.H. Hinz

Dissertations

Wilson disease protein (WLNP) is a P_1b-type ATPase crucial for maintaining copper homeostasis in humans. Mutations in this protein result in the autosomal recessive disorder Wilson disease, a condition characterized by copper accumulation in the liver and brain. WLNP provides copper for incorporation into cuproproteins and exports excess copper into the bile for excretion. There are six metal-binding domains (MBDs) in WLNP, found within the first 650 amino acids of this 1,465 amino acid protein. Though each MBD has a different amino acid sequence, all MBDs possess a similar ferredoxin fold with a conserved hydrophobic core and a …

An Investigation Into The Mechanical And Aesthetic Properties Of New Generation Coated Nickel-Titanium Wires In The As-Received State And After Clinical Use, T. Gerard Bradley, David W. Berzins, Nicholas Valeri, Jessica E. Pruszynski, Theodore Eliades, Christos Katsaros

School of Dentistry Faculty Research and Publications

The orthodontic profession is constantly seeking to improve and optimize the aesthetics of orthodontic wires since the introduction of aesthetic brackets. Nickel-titanium (NiTi) wires since their introduction to orthodontics (Andreasen and Hilleman, 1971) have been extensively researched in vitro and are used as an initial levelling and aligning archwire because of its properties of springback and superelasticity (Burstone et al., 1985; Miura et al., 1986; Leu et al., 1990; Bishara et al., 1995; Bradley et al., 1996; Biermann et al., 2007; Berzins and Roberts 2010). Aesthetic wires are usually either coated NiTi wires or composite wires of reinforced polymers. Shape …

Individual, Disease, And Work-Related Factors Associated With Work Patterns, Presenteeism And Sick Pay Policy Of The Colorectal Cancer Survivor After Treatment, Kristin A. Roper

Graduate Doctoral Dissertations

Participation of colorectal cancer survivors (CRC) in the workforce has been described by clinicians, survivors, and researchers as a way to improve mood, quality of life (QOL), and survival. Maintaining self-esteem and financial independence have also been attributed to continued employment of the CRC survivor. The purpose of this cross-sectional survey was to describe patterns of employment of the CRC survivor and to examine the individual, disease, and work-related factors that influence presenteeism and perceived adequacy of sick pay (ASP) policy. The Conceptual Model of Nursing and Health Policy and the Pathways to Work Life Recovery guided the design, selection …

Combined Effects Of Mdma And Ethanol On Locomotor Activity And Place Conditioning In Male And Female Adolescent Sprague-Dawley Rats, Keli A. Herr

Masters Theses

MDMA, ("Ecstasy") is commonly abused in combination with ethanol (EtOH). Relatively few preclinical studies have investigated sex differences in animal models of polysubstance use. The current study employed a conditioned place preference (CPP) procedure to assess the behavioral effects of the co-administration ofMDMA /EtOH in 32 male and 32 female adolescent Sprague-Dawley rats. Following a 15 min habituation trial, eight 30-min conditioning trials were conducted in two- compartment chambers with different environmental cues. Before each drug conditioning trials, rats were administered intraperitoneal (i.p.) injections of MDMA(6.6 mg/kg), EtOH (1.5 g/kg), MDMA (6.6 mg/kg) and EtOH (1.5 g/kg), or saline. Prior …

Inhibition Of Food Intake By Pacap In The Hypothalamic Ventromedial Nuclei Is Mediated By Nmda Receptors, Jon M. Resch, Brian Maunze, Kailynn A. Phillips, Sujean Choi

Biomedical Sciences Faculty Research and Publications

Central injections of pituitary adenylate cyclase-activating polypeptide (PACAP) into the ventromedial nuclei (VMN) of the hypothalamus produce hypophagia that is dependent upon the PAC1 receptor; however, the signaling downstream of this receptor in the VMN is unknown. Though PACAP signaling has many targets, this neuropeptide has been shown to influence glutamate signaling in several brain regions through mechanisms involving NMDA receptor potentiation via activation of the Src family of protein tyrosine kinases. With this in mind, we examined the Src-NMDA receptor signaling pathway as a target for PACAP signaling in the VMN that may mediate its effects on feeding behavior. …

Pilot Study To Assess Benefit Of Virtual Reality Game System, Wii, On Balance And Gait In Persons With Parkinson's Disease, Peter J. Barbour Md, Amy L. Kerstetter Pt, Allyn Danni Pt, Ncs, Atp, Mscs, Jolene Hammer Pt, Michael J. Weiss Mph, Sandra M. Tremblay Pt, Ms, Cws, Mscs

Department of Medicine

No abstract provided.

The Effect Of Shortening Door To Balloon Time (<90 Minutes) In Stemi Patients Transferred From Outside Hospitals, Ataul Qureshi Md, Yassir Nawaz Md, Navin K. Subrayappa Md, Orlando E. Rivera Rn, Nainesh C. Patel Md

Department of Medicine

No abstract provided.

Pulsating Left Breast After Trans-Apical Aortic Valve Implantation: An Ominous Sign, Yassir Nawaz Md, Navin K. Subrayappa Md, Sumit Duggal Md, Ataul Qureshi Md, Muppidi Raghunandan Md

Department of Medicine

No abstract provided.

An Uncommon Complication During Trans-Aortic Valve Replacement, Sanjeev Nair Md, Yassir Nawaz Md, Nainesh C. Patel Md, David A. Cox Md, William Combs Md, Raymond L. Singer Md, J Patrick Kleaveland Md

Department of Medicine

No abstract provided.

Drug Resistant Tuberculosis: Challenges Of Urbanization, Rumina Hasan

Department of Pathology and Laboratory Medicine

No abstract provided.

From Sea To Shining Sea: Force Health Management Of Infectious Diseases In A Cross-Global Deployment Flux Toward Tropical Environments, Joanna M. Nelms

Master of Public Health Program Student Publications

Infectious diseases in fighting armies are a pestilence as old as war itself. The history of the United States military is rich in successes of innovation and lessons learned in failure in the prevention and treatment of infectious diseases. Over the nearly two and a half centuries of American warfare, military research and development have contributed greatly to advancements in vaccines, medical treatments, and other control and prevention strategies for tropical and other infectious diseases. Current deployments in desert environments have provided continued research and progress in infectious disease control, treatment, and prevention, despite a relative decrease in civilian medical …

Association Between Symptomatic Vulvovaginal Candidiasis And Hiv Rna Levels In Plasma And Genital Secretions Among Women On Haart, Teke Apalata, William H. Carr, Benjamin Longo-Mbenza, Willem A. Sturm, P. Moodley

Publications and Research

Background. Genital tract (GT) inflammation plays a major role in HIV transmission. We aimed to determine the association between symptomatic vulvovaginal candidiasis (VVC) and HIV RNA levels in plasma and GTs of HIV-infected women on highly active antiretroviral therapy (HAART).

Method. Women with VVC on HAART were recruited from a primary healthcare clinic in KwaZulu-Natal Province, South Africa, between June 2011 and December 2011. VVC was diagnosed clinically, supported by Gram staining and culture of genital secretions. HIV RNA load was determined by reverse transcription polymerase chain reaction. CD4+ counts were obtained from patients’ medical records.

Results. Plasma HIV RNA …

False Negative Studies May Systematically Contaminate The Literature On The Effects Of Inducers In Neuropsychopharmacology. Part Ii: Focus On Bipolar Disorder, Jose De Leon

Psychiatry Faculty Publications

No abstract provided.

Low-Cost Strider For Guatemala, Nicole Catherine Cooper, Gonzalo Hernandez, Jared W. Tower

Mechanical Engineering

The purpose of this project was to create a strider, a type of standing rehabilitation device, for children in developing countries who have trouble walking and supporting their full body weight. The project was initially brought to us by Cal Poly professor Brian Self, who had visited a clinic in San Marcos and determined that there were children there who had difficulties with walking and were a need for a rehabilitation device. The team discussed the problem with Dr. Self, Matt Robinson (a local San Luis Obispo prosthetist), and Cal Poly physics professor Pete Schwartz, all of whom had visited …