Medicine and Health Sciences Commons^™

Public Health Service Options For Affordable And Accessible Noncommunicable Disease And Related Chronic Disease Prevention And Management, Sharon Brownie, Andrew P. Hills, Rachel Rossiter

School of Nursing & Midwifery, East Africa

Globally, nations are confronted with the challenge of providing affordable health services to populations with increasing levels of noncommunicable and chronic disease. Paradoxically, many nations can both celebrate increases in life expectancy and bemoan parallel increases in chronic disease prevalence. Simply put, despite living longer, not all of that time is spent in good health. Combined with factors such as rising levels of obesity and related noncommunicable disease, the demand for health services is requiring nations to consider new models of affordable health care. Given the level of disease burden, all staff, not just doctors, need to be part of …

Substance Abuse Prevention In American Indian And Alaska Native Communities: Exploration Of Guiding Theoretical Underpinnings And Theoretical Fit In Practice, Margaret L. Walsh

USF Tampa Graduate Theses and Dissertations

The purpose of this study was to identify ways Indigenous theoretical perspectives may guide current and future substance abuse prevention programs. As the majority of current theories guiding substance abuse prevention programs in American Indian and Alaska Native communities stem from Western ideologies and lack Indigenous perspectives, there is a paucity of research on theoretical underpinnings for Indigenous perspectives in AI/AN communities and their potential role in substance abuse prevention programming. It is well known that when programs are theoretically connected to the communities in which they are implemented, they are more likely to be accepted, accurately measured, and sustained …

Rare Presentation Of A Massive Intermittent Upper Gastrointestinal Bleed, Bonnie Patek Do, Matthew Sullivan Do, Shashin Shah Md

Department of Medicine

No abstract provided.

Research Brief: "Veterans’ Attitudes Toward Work And Disability Compensation: Associations With Substance Abuse", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This study compares attitudes towards employment and service-connected disabilities among substance using and non-using veterans. In practice, veterans place a high value on being employed, regardless of whether they use substances; however, veterans who used substances were more likely to express fear of losing disability benefits if they became employed. In policy, state-level agencies and programs might work with counseling centers to determine the most productive ways to address the specific employment needs of veterans with disabilities and/or substance use issues. Suggestions for future study include sampling larger populations on a randomized basis to ensure that the results found here …

The Santa Clara, 2014-10-23, Santa Clara University

The Santa Clara

No abstract provided.

Factors Involved In Early Age Dental Visits, Lillian Brooke Mcneal

Mahurin Honors College Capstone Experience/Thesis Projects

Today, more children are diagnosed with Early Childhood Caries (ECC) than at any other time in modern history. It is noted that Early Childhood Caries (ECC) is now the most common infectious disease among children and occurs 5 times more than asthma (America Academy of Pediatric Dentistry, 2014). Considering the extent of this disease, it is imperative to determine the cause of it and factors involved in the control.

In order to begin this study, one must first analyze different patients and their living conditions, along with the frequency of dental visits and when the first dental visit occurred. What …

Hookah: A Fun Fad Or Harmful Habit?, Amy Gee Broadrick

Mahurin Honors College Capstone Experience/Thesis Projects

Hookah smoking has been a well-known activity in the Middle East for hundreds of years. More recently, hookah has become a worldwide phenomenon, especially in the United States of America. It is important to know why people choose this habit, and specifically why teenagers and young adults are becoming the main frequent users.

An interview session consisting of a questionnaire was the methodology used in this study. This session involved a total of twenty individuals. Ten of these individuals were people who actively participated in smoking hookah. The other ten subjects were individuals who do not engage in hookah smoking. …

Burning Pain Secondary To Clozapine Use: A Case Report., Bradley Linton, Rachel Fu, Penny A Macdonald, Hooman Ganjavi

Brain and Mind Institute Researchers' Publications

BACKGROUND: The first of the atypical antipsychotics introduced in the 1970s, clozapine remains the most efficacious neuroleptic to this day. However, serious and potentially fatal side effects have necessitated careful regular monitoring among prescribing clinicians. Some adverse effects (e.g. ischaemic bowel) remain under recognized, while newly identified adverse effects continue to be described in the literature.

CASE PRESENTATION: In this report, we describe a healthy 43-year old Caucasian male who experienced onset of a full body deep burning pain several months after the onset of treatment with clozapine. The pain worsened over time, ceased with cessation of treatment, and returned …

Latexin Sensitizes Leukemogenic Cells To Gamma-Irradiation-Induced Cell-Cycle Arrest And Cell Death Through Rps3 Pathway, Y. You, R. Wen, R. Pathak, A. Li, W. Li, D. St. Clair, M. Hauer-Jensen, D. Zhou, Ying Liang

Toxicology and Cancer Biology Faculty Publications

Leukemia is a leading cause of cancer death. Recently, the latexin (Lxn) gene was identified as a potential tumor suppressor in several types of solid tumors and lymphoma, and Lxn expression was found to be absent or downregulated in leukemic cells. Whether Lxn functions as a tumor suppressor in leukemia and what molecular and cellular mechanisms are involved are unknown. In this study, the myeloid leukemogenic FDC-P1 cell line was used as a model system and Lxn was ectopically expressed in these cells. Using the protein pull-down assay and mass spectrometry, ribosomal protein subunit 3 (Rps3) was identified as a …

Improving Access To Care: Mobile Dental Units, Caitlin Stephens

Mahurin Honors College Capstone Experience/Thesis Projects

Despite efforts to improve oral health, untreated childhood tooth decay continues to be a major concern in the state of Kentucky. It is said that an estimated 42.8 percent of children in Kentucky suffer from early childhood caries (ECC) before the age of five and 39.3 percent of these children have never been in a dental office (The Kentucky Oral Health Summit). Another study conducted revealed that approximately 20 percent of preschoolers, 50 percent of second graders and 75 percent of 15 years olds are affected by untreated tooth decay (Kentucky’s Dental Access Summit, 2013). What are the major issues …

Copy Number Variation In The Horse Genome, Sharmila Ghosh, Zhipeng Qu, Pranab J. Das, Erica Fang, Rytis Juras, E. Gus Cothran, Sue Mcdonell, Daniel G. Kenney, Teri L. Lear, David L. Adelson, Bhanu P. Chowdhary, Terje Raudsepp

Maxwell H. Gluck Equine Research Center Faculty Publications

We constructed a 400K WG tiling oligoarray for the horse and applied it for the discovery of copy number variations (CNVs) in 38 normal horses of 16 diverse breeds, and the Przewalski horse. Probes on the array represented 18,763 autosomal and X-linked genes, and intergenic, sub-telomeric and chrY sequences. We identified 258 CNV regions (CNVRs) across all autosomes, chrX and chrUn, but not in chrY. CNVs comprised 1.3% of the horse genome with chr12 being most enriched. American Miniature horses had the highest and American Quarter Horses the lowest number of CNVs in relation to Thoroughbred reference. The Przewalski horse …

Mechanisms Of T-B Cell Cooperation Important For Mog Antibody Mediated Demyelination, Dusanka S. Skundric

Neurology Faculty Publications

No abstract provided.

Monitoring And Use Of Social Media In Emergncy Management In Florida, Leila Martini

USF Tampa Graduate Theses and Dissertations

The emergence of mobile technologies and social media applications has led to a shift in the emergency/disaster related communication environment. Citizens are playing an increasingly important role in providing real time information to emergency organizations. This shift has resulted in an expectation by the public that emergency management (EM) organizations monitor and respond to calls for help disseminated via these applications. The purpose of this study is to explore the extent to which Florida EM agencies have incorporated the monitoring of social media into their organizational processes.

The state of social media use in Florida is under researched. In this …

Open Access And The Health Professions, Musselman Library

Open Access Week at Gettysburg College

Health Sciences students at Gettysburg College have bountiful access to scholarly and medical publications, but what happens after graduation? When you enter a health profession, will you be able to access the information you need to make informed decisions on the job?

Students are asking hard questions about the cost of information, who pays, and why it matters (see this SURGE blog post for one perspective: Information – Access:Denied). Learn more about the publishing system that fuels your learning, including the growing importance of “open access” publishing.

Please join us for a fun program during Open Access Week. This …

Enhanced Precision In The Analysis Of Randomized Trials With Ordinal Outcomes, Iván Díaz, Elizabeth Colantuoni, Michael Rosenblum

Johns Hopkins University, Dept. of Biostatistics Working Papers

We present a general method for estimating the effect of a treatment on an ordinal outcome in randomized trials. The method is robust in that it does not rely on the proportional odds assumption. Our estimator leverages information in prognostic baseline variables, and has all of the following properties: (i) it is consistent; (ii) it is locally efficient; (iii) it is guaranteed to match or improve the precision of the standard, unadjusted estimator. To the best of our knowledge, this is the first estimator of the causal relation between a treatment and an ordinal outcome to satisfy these properties. We …

Hydroxamic Acid-Based Histone Deacetylase (Hdac) Inhibitors Can Mediate Neuroprotection Independent Of Hdac Inhibition, Sama Sleiman, Yan-Ling Zhang, Jennifer Gale, Manuela Basso, Giovanni Coppola, John T. Pinto, Rajiv Ratan

NYMC Faculty Publications

Histone deacetylase (HDAC) inhibition improves function and extends survival in rodent models of a host of neurological conditions, including stroke, and neurodegenerative diseases. Our understanding, however, of the contribution of individual HDAC isoforms to neuronal death is limited. In this study, we used selective chemical probes to assess the individual roles of the Class I HDAC isoforms in protecting Mus musculus primary cortical neurons from oxidative death. We demonstrated that the selective HDAC8 inhibitor PCI-34051 is a potent neuroprotective agent; and by taking advantage of both pharmacological and genetic tools, we established that HDAC8 is not critically involved in PCI-34051's …

Insights Into The Problem Of Alarm Fatigue With Physiologic Monitor Devices: A Comprehensive Observational Study Of Consecutive Intensive Care Unit Patients, Barbara J. Drew, Patricia Harris, Jessica K. Zègre-Hemsey, Tina Mammone, Daniel Schindler, Rebeca Salas-Boni, Yong Bai, Adelita Tinoco, Quan Ding, Xiao Hu

Collected Faculty Scholarship

Purpose: Physiologic monitors are plagued with alarms that create a cacophony of sounds and visual alerts causing ‘‘alarm fatigue’’ which creates an unsafe patient environment because a life-threatening event may be missed in this milieu of sensory overload. Using a state-of-the-art technology acquisition infrastructure, all monitor data including 7 ECG leads, all pressure, SpO2, and respiration waveforms as well as user settings and alarms were stored on 461 adults treated in intensive care units. Using a well-defined alarm annotation protocol, nurse scientists with 95% inter-rater reliability annotated 12,671 arrhythmia alarms.

Results: A total of 2,558,760 unique alarms occurred in the …

Prioritization, Accountability And Engagement: Programmatic Strategies For All Three To Impact Patient Safety, Jody Shigo Rn, Cmsrn

Patient Care Services / Nursing

No abstract provided.

Managing Observation: The Value Of An Observation Unit, Carol Teets

Patient Care Services / Nursing

No abstract provided.

Enhancing Nurse Residents’ Transition To Practice Through An Evidence-Based Practice Project: The Volunteer Partners Walking Program, Tamara L. Burket Msn, Acns-Bc, Gcns-Bc, Ccrn, Fgnla

Patient Care Services / Nursing

No abstract provided.

Predictors Of Infections Following Cranioplasty: A Retrospective Review Of A Large Single Center Study., Mario Zanaty, Nohra Chalouhi, Md, Robert M Starke, Rohan Chitale, Md, Shannon Hann, Md, Cory D Bovenzi, Mark P Saigh, Eric W Schwartz, Emily S I Kunkel, Alexandra S Efthimiadis-Budike, Pascal Jabbour Md, Richard Dalyai, Robert H. Rosenwasswer Md, Stavropoula Tjoumakaris

Department of Neurosurgery Faculty Papers

Introduction. The variables that predispose to postcranioplasty infections are poorly described in the literature. We formulated a multivariate model that predicts the risk of infection in patients undergoing cranioplasty. Method. Retrospective review of all patients who underwent cranioplasty following craniectomy from January, 2000, to December, 2011. Tested predictors were age, sex, diabetic status, hypertensive status, reason for craniectomy, urgency status of craniectomy, location of cranioplasty, reoperation for hematoma, hydrocephalus postcranioplasty, and material type. A multivariate logistic regression analysis was performed. Results. Three hundred forty-eight patients met the study criteria. Infection rate was 26.43% (92/348). Of these cases with infection, 56.52% …

Loss Of Hif-1Α In The Notochord Results In Cell Death And Complete Disappearance Of The Nucleus Pulposus., Christophe Merceron, Laura Mangiavini, Alexander Robling, Tremika Leshan Wilson, Amato J Giaccia, Irving Shapiro, Ernestina Schipani, Makarand V Risbud

Department of Orthopaedic Surgery Faculty Papers

The intervertebral disc (IVD) is one of the largest avascular organs in vertebrates. The nucleus pulposus (NP), a highly hydrated and proteoglycan-enriched tissue, forms the inner portion of the IVD. The NP is surrounded by a multi-lamellar fibrocartilaginous structure, the annulus fibrosus (AF). This structure is covered superior and inferior side by cartilaginous endplates (CEP). The NP is a unique tissue within the IVD as it results from the differentiation of notochordal cells, whereas, AF and CEP derive from the sclerotome. The hypoxia inducible factor-1α (HIF-1α) is expressed in NP cells but its function in NP development and homeostasis is …

Rectal Polyp With Atypical Lymphoid Infiltrate; Rectal Lymphoma Or Rectal Tonsil, Dalya El Tawil Md, Adam R. Paul Do

Department of Pediatrics

No abstract provided.

2014 October 21 - Medical Student Education Committee Retreat Minutes, Medical Student Education Committee, East Tennessee State University

Medical Student Education Committee Minutes

No abstract provided.

The Implications Of Regional And National Demographic Projections For Future Gms Costs In Ireland Through To 2026, Aisling Conway Lenihan, Martin Keneally, Noel Woods, Andreas Thummel, Marie Ryan

Dept. of Management & Enterprise Publications

As the health services in Ireland have become more resource-constrained, pressure has increased to reduce public spending on community drug schemes such as General Medical Services (GMS) drug prescribing and to understand current and future trends in prescribing. The GMS scheme covers approximately 37% of the Irish population in 2011 and entitles them, inter alia, to free prescription drugs and appliances. This paper projects the effects of future changes in population, coverage, claims rates and average claims cost on GMS costs in Ireland.

12-Month Outcomes Of Community Care Teams For Primary Care Practices Transforming Towards Pcmh, Carol A. Foltz Phd, Deborah Swavely Dnp, Rn, Nyann Biery Ms, Nancy Gratz Mpa, Pcmh-Cce, Hannah D. Paxton Rn, Mph, Susan Lawrence Ms, Cmac, Fache

Patient Care Services / Nursing

No abstract provided.

Ph-Sensitive Mucoadhesive Film-Forming Gels And Wax-Film Composites Suitable For Topical And Mucosal Delivery Of Molecules, Russell J. Mumper, Michael Jay

Pharmaceutical Sciences Faculty Patents

The present invention relates to pH-sensitive mucoadhesive film-forming gels and wax-film composites suitable for topical and mucosal delivery of molecules of interest, namely active pharmaceuticals. The gels comprise a pharmaceutically acceptable pH-sensitive polymer that responds to a lowering of pH by precipitating into films when in contact with the skin or mucosal surface. The films also comprise an adhesive polymer that allows the film to remain in contact with the tissue for an extended period of time. The wax-film composites comprise a bi-layer film having both the said pH-sensitive mucoadhesive layer to promote strong adherence to the skin and mucosal …

Health Insurance Among Young Adults Rebounds Post Recession: More Become Dependents On A Parent's Plan After Aca Extends Coverage To Adult Children, Michael J. Staley, Jess Carson

Carsey Publications

While much of the existing research explores young adults' insurance only in the post-recession period (that is, 2010 to present), authors Michael Staley and Jessica Carson assess young adults' rates of coverage within and beyond the context of the recession by examining changes across the entire 2007 to 2012 period.

Clinical Vignette: A Case Of Successful Surgical Decortication For Empyema With Trapped Lung, In A Patient With Decompensated Cirrhosis, Tripti R. Chopade, Md, She-Yan Wong, Md, David A. Sass, Md, Scott W. Cowan, Md, Jesse M. Civan, Md

Division of Gastroenterology and Hepatology Faculty Papers

Introduction

Hepatic hydrothorax (HH) is a difficult-to-control complication of cirrhosis. Chest tube (CT) drainage is an option for management of HH, but is associated with a high rate of secondary infection and other complications.

Markedly Elevated Ca 19-9 In A Case Of Mirizzi’S Syndrome: An Atypical Presentation, Saba Ahmad Md, Hiral N. Shah Md, Patrick Hickey Do, Matthew Sullivan Do

Department of Medicine

No abstract provided.