Medicine and Health Sciences Commons^™

Principles Of Manipulative Management Of Essential Hypertension, Richard S. Koch

Koch Collection, Papers of Richard S Koch, DO

Rough draft of article on musculoskeletal findings and treatment associated with hypertension.

"Health" Magazine Article - Osteopathic Concept And Spinal Study Statistics In Children, Richard S. Koch

Koch Collection, Papers of Richard S Koch, DO

Rough Draft for Dr. Koch's contribution to an article in Health magazine discussing spinal findings in children and their correlation in neck and back pain and other dysfunctions.

General Principles Of Spinal Treatment, Richard S. Koch

Koch Collection, Papers of Richard S Koch, DO

Discusses mechanism behind spinal asymmetry and back pain and then provides therapy modalities and images to demonstrate these treatment options.

Spinal Asymmetries - Their Determination, Incidence And Pathophysiologic Association, Richard S. Koch

Koch Collection, Papers of Richard S Koch, DO

Abstract for talk at Madrid FIMM Convention on spinal asymmetries

Neck Care, Richard S. Koch

Koch Collection, Papers of Richard S Koch, DO

Hand-out given to Dr Koch's patients, that provided plan following their neck treatment.

Poignant Pointers From 60 Years Treating Backs And Necks - Goals, Richard S. Koch

Koch Collection, Papers of Richard S Koch, DO

Article discussing etiology of chronic back and neck aches and how to reduce/remove these causes and permanently strengthen back via fibrin therapy; "back-ache genesis"; in support of fibrotherapy.

Justifying Postural X-Rays To Reveal Asymmetries, Richard S. Koch

Koch Collection, Papers of Richard S Koch, DO

Abstract which attempts to justify the use of spinal x-rays to reveal spinal asymmetries that correlate with back pain and visceral dysfunction/diseases.

Personal Notes On Asthma And Colds, Richard S. Koch

Koch Collection, Papers of Richard S Koch, DO

Dr Koch's personal notes on asthma and colds.

Manipulation And Physical Medicine In Abdominal Disorders, Richard S. Koch

Koch Collection, Papers of Richard S Koch, DO

Discusses correlation between gastrointestinal complaints and spinal asymmetry findings.

Exercises For Breathing, Richard S. Koch

Koch Collection, Papers of Richard S Koch, DO

Hand-out for patients discussing exercises for breathing.

Asthma & Cardiac Physician Treatment (Techniques), Richard S. Koch

Koch Collection, Papers of Richard S Koch, DO

Dr Koch's notes on treatment techniques used for his patients with asthma/cardiac issues.

2013 Founders Day, Philadelphia College Of Osteopathic Medicine

Founders Day Programs

The 2013 Founders Day OJ Snyder Memorial Medal recipient was Saul Jeck, DO, FACOOG. The Philadelphia Campus Mason W Pressly Memorial Medal Recipient was Mark A. Vila, MBA (DO '13). The Georgia campus Mason W Pressly Memorial Medal Recipient was Annise K. Chung, (DO '13).

Synapsis: Georgia Campus (2013), Philadelphia College Of Osteopathic Medicine

All Yearbooks

The yearbook includes Class Officers, White Coat Ceremony, Holiday Luncheon, GOMA Banquet, Cadaver Ceremony, Cardiology, Clubs, Emergency Medicine, Breast Cancer Awareness, Adopt-a-Road, Bowling, Ob-Gyn, Play, Surgery, CMDA, Sigma Sigma Phi, SSPh, (ΣΣΦ), Sports Medicine, Student Interest Group in Neurology, Undergraduate American Academy of Osteopathy, UAAO, Internal Medicine, International Medicine, DO Day on the Hill, Student Osteopathic Medical Association, SOMA, American Osteopathic Association, AOA, Conferences, Prom, Orientation, Suturing Clinic and Scrubs, Student Association of Military Osteopathic Physicians & Surgeons, AMOPS, Halloween, Casino Night, Student American Osteopathic Academy of Orthopedics, Green Team, Corley Elementary Volunteering Event, Casting Clinic, Convocation, OMM Lab, Gwinnett …

Analysis Of Autophagy And Inflammasome Regulation In Neuronal Cells And Monocytes Infected With Chlamydia Pneumoniae: Implications For Alzheimer’S Disease, Brian J. Balin, Christine J. Hammond, Juliana Zoga, Ahmad B. Cader, Annette K. Slutter, Jonathan M. Anzman, Ian Kohler, Susan T. Hingley, Denah M. Appelt

Scholarly Posters

Objectives: Our laboratory has been studying the role of infection with the obligate intracellular bacterium Chlamydia pneumoniae in sporadic late-onset Alzheimer disease (LOAD). This infection may be a trigger for the pathology observed in LOAD as a function of initiating changes in gene regulation following entry of the organism into the brain. As such, we are analyzing how this infection can promote changes in autophagy and inflammasome gene regulation as both have been shown to be altered in LOAD. Methods: Human SKNMC neuronal cells and THP1 monocytes were infected in vitro for 24-72 hrs with a laboratory strain of Chlamydia …

Personalizing Aac For People With Aphasia: The Role Of Text And Pictures, Aimee R. Dietz, Kristy S.E. Weissling, Julie Griffith, Miechelle L. Mckelvey

Department of Special Education and Communication Disorders: Faculty Publications

Over time, and with intensive instruction, people with aphasia (PWAs) can learn to use grid-based, categorically organized, high-technology AAC layouts during structured tasks (e.g., Hough & Johnson, 2009). In an effort to reduce the training intensity required to teach PWAs to use AAC; researchers developed visual scene displays (VSDs), designed to complement the residual cognitive and linguistic abilities of PWAs by tapping their intact episodic memory. VSD interfaces incorporate personally relevant (PR) photos, text, and speech output (Dietz, McKelvey, & Beukelman, 2006; Weissling & Beukelman, 2006). VSDs appear to facilitate improved communication success (e.g., McKelvey, Dietz, Hux, Weissling, & Beukelman, …

Electropalatography As An Adjunct To Nonspeech Orofacial Myofunctional Disorder Assessments: A Feasibility Study, Alana Mantie-Kozlowski, Kevin M. Pitt

Department of Special Education and Communication Disorders: Faculty Publications

The purpose of this study was to determine if electropalatography (EPG) would be a useful adjunct and feasible option for those conducting clinical assessments of individuals with suspected nonspeech orofacial myofunctional disorders (NSOMD). Three females (two adults, one child) were referred by their orthodontist for assessment of suspected NSOMD. Three adults and one child without NSOMD were recruited for the purpose of evaluating methodological construct, and to provide comparisons for participants with NSOMD. Using EPG, lingual-palatal timing and contact patterns of 105 saliva swallows (45 with NSOMD, 60 without NSOMD) were analyzed by compartmentalizing the sensor display and tracking the …

Rhodotorula Minuta Fungemia In A Ewe Lamb, C. G. Chitko-Mckown, K. A. Leymaster, M. P. Heaton, D. D. Griffin, J. K. Veatch, S. A. Jones, M. L. Clawson

School of Veterinary and Biomedical Sciences: Faculty Publications

An 8-month-old crossbred ewe, normal upon physical examination, was humanely euthanized for tissue collection. After approximately 3 weeks in tissue culture, fungi began budding out of cells obtained from the choroid plexus. After an additional 3 weeks, budding was observed in kidney cell cultures and eventually in monocyte cultures as well. Serum from the lamb was submitted to the Veterinary Diagnostic Laboratory at Colorado State University for fungal diagnosis and was found negative for Aspergillus, Blastomyces, Coccidioidomycosis and Histoplasmosis. DNA was isolated from fungi collected from tissue culture supernatants and used in a set of pan-fungal PCR assays with …

Interferon Inducible Protein Ifi35 Negatively Regulates Rig-I Antiviral Signaling And Supports Vesicular Stomatitis Virus Replication, Anshuman Das, Phat X. Dinh, Debasis Panda, Asit K. Pattnaik

School of Veterinary and Biomedical Sciences: Faculty Publications

In a genome-wide siRNA screen, we recently identified the interferon (IFN) inducible protein 35 (IFI35, also known as IFP35) as a factor required for VSV infection. Studies reported here were conducted to further understand the role and requirement of IFI35 in VSV infection. Consistent with the siRNA screening data, we found that depletion of IFI35 led to reduced VSV replication at the level of viral gene expression. Although no direct interaction of IFI35 with the viral replication machinery was observed, we found that IFI35 negatively regulated the host innate immune response and rescued poly(I:C)-induced inhibition of VSV replication. Promoter-driven reporter …

Sequence-Optimized And Targeted Double-Stranded Rna As A Therapeutic Antiviral Treatment Against Infectious Myonecrosis Virus In Litopenaeus Vannamei, J. Dustin Loy, Duan S. Loy, Mark A. Mogler, Bruce Janke, Kurt Kamrud, D. L. Hank Harris, Lyric C. Bartholomay

School of Veterinary and Biomedical Sciences: Faculty Publications

Infectious myonecrosis virus (IMNV) is a significant and emerging pathogen that has a tremendous impact on the culture of the Pacific white shrimp Litopenaeus vannamei. IMNV first emerged in Brazil in 2002 and subsequently spread to Indonesia, causing large economic losses in both countries. No existing therapeutic treatments or effective interventions currently exist for IMNV. RNA interference (RNAi) is an effective technique for preventing viral disease in shrimp. Here, we describe the efficacy of a double-stranded RNA (dsRNA) applied as an antiviral therapeutic following virus challenge. The antiviral molecule is an optimized dsRNA construct that targets an IMNV sequence …

Bovine Herpes Virus 1 (Bhv-1) And Herpes Simplex Virus Type 1 (Hsv-1) Promote Survival Of Latently Infected Sensory Neurons, In Part By Inhibiting Apoptosis, Clinton Jones

School of Veterinary and Biomedical Sciences: Faculty Publications

α-Herpesvirinae subfamily members, including herpes simplex virus type 1 (HSV-1) and bovine herpes virus 1 (BHV-1), initiate infection in mucosal surfaces. BHV-1 and HSV-1 enter sensory neurons by cell-cell spread where a burst of viral gene expression occurs. When compared to non-neuronal cells, viral gene expression is quickly extinguished in sensory neurons resulting in neuronal survival and latency. The HSV-1 latency associated transcript (LAT), which is abundantly expressed in latently infected neurons, inhibits apoptosis, viral transcription, and productive infection, and directly or indirectly enhances reactivation from latency in small animal models. Three anti-apoptosis genes can be substituted for LAT, which …

Relevance Of Molecular Mimicry In The Mediation Of Infectious Myocarditis, Chandirasegaran Massilamany, Sally A. Huber, Madeleine W. Cunningham, Jay Reddy

Jay Reddy Publications

Heart disease, the leading cause of death in humans, is estimated to affect one in four American adults in some form. One predominant cause of heart failure in young adults is myocarditis, which can lead to the development of dilated cardiomyopathy, a major indication for heart transplantation. Environmental microbes, including viruses, bacteria, and fungi that are otherwise innocuous, have the potential to induce inflammatory heart disease. As the list is growing, it is critical to determine the mechanisms by which microbes can trigger heart autoimmunity and, importantly, to identify their target antigens. This is especially true as microbes showing structural …

The Design, Synthesis, And Biological Evaluation Of Aplysinopsin Analogs As Potential Neuromodulators, Kevin Lewellyn

Electronic Theses and Dissertations

Aplysinopsins are tryptophan-derived natural products that have been isolated from a variety of marine organisms and have been shown to possess a range of biological activities. Initial synthesis of a library of 50 aplysinopsin analogs revealed that of the 12 serotonin receptor subtypes and 34 other CNS receptors, aplysinopsin analogs shoa high affinity for the 5-HT2B and 5-HT2C receptor subtypes, with selectivity for 5-HT2B over 5-HT2C. Bromination at C-4 and C-5 of the indole ring resulted in greater binding affinities, with Ki's as low as 35 nM. In addition, biological evaluation of the MAO-A and MAO-B inhibitory activities of these …

Seaweed-Based Functional Foods, Nissreen Abu-Ghannam, Sabrina Cox

Books/Book Chapters/ Proceedings

Functional foods are foods that provide health benefits in addition to basic nutrition. They are categorized through identification, characterization, and evaluation of the health-promoting properties they present. New high-value nutrition and wellness products, manufactured by reformulation of existing products through development of nutraceutical or functional foods, present an exciting opportunity for the food industry worldwide. Many bioactive constituents to which a beneficial physiological function has been directly or indirectly attributed, originating mainly from plant extracts, have been incorporated in already existing food products or have been commercialized in the form of pharmaceutical products such as pills, capsules, solutions, and gels …

Measuring The Impact Of Health Education Modules In Cameroon, West Africa, Paulette A. Chaponniere, Susan M. Cherup, Lillie Lodge

Peer Reviewed Articles

Each year, more than two million people die from diarrhea-associated diseases. Although there is a global need for safe drinking water, culturally appropriate health teaching is essential to behavior change. This study evaluated the impact of a health education program in a small rural community in Cameroon. Flash cards and a modified version of the CDC-KPC 2000 survey were used to collect data in 57 homes. Children who lived in households with working Manz BioSand filters were less likely to have had diarrhea in the 2 weeks prior to the evaluation. There remained a gap between health knowledge and healthy …

Upper Extremity Kinematics In Sonographers During Kidney Scanning, Jennifer Pocratsky, Blake Ashby, Jeanine Beasley

Peer Reviewed Articles

To understand the mechanisms involved that lead to the high prevalence of work-related musculoskeletal disorders in sonographers, this motion capture study evaluated upper extremity kinematics during kidney scans. The purpose of this study was to provide an evaluation of joint ranges of motion during scanning, which could be helpful in assessing risk of injury. A Vicon MX motion capture system recorded reflective marker positions while four sonographers scanned a volunteer’s kidneys. The results indicated that sonographers were scanning with their shoulders in flexion, abduction, and external rotation. The elbows were in flexion and the wrists in extension in all cases …

A Qualitative Study Of Middle School Students’ Perceptions Of Unstructured Time, Stephanie L. Hovick, Justine N. Gonzalez Bratt, Kristin M. Cameron

Pediatrics

OBJECTIVE: The purpose of this study was to identify middle school students’ perceptions of unstructured time by determining physical and leisure activities the students would want to have available for their use at school.

METHOD: A researcher developed questionnaire (Students’ Leisure Time Questionnaire) was used to interview 23 middle school students (ages 11 to 15) regarding their perceptions of activities during unstructured time. A phenomenological design was used, incorporating open-ended qualitative questions.

RESULTS: The students were able to identify activities in which they would like to participate during their unstructured time at school. Students primarily indicated football and basketball as …

A Descriptive Study Of The Leadership Role Of Community Health Ambassadors On Diabetes-Related Health Behaviors, Barbara Pullen-Smith

Dissertations

Diabetes is a chronic disease that bears a disproportionate burden among African American populations. The lack of access to affordable, culturally appropriate health care is a key barrier to effective diabetes prevention or disease management for racial/ethnic minority populations. Living in public housing communities, with concentrated poverty, exacerbates the burden of diabetes and reduces access to screening and early detection services to prevent the onset of diabetes. The purpose of the study was to describe the leadership role of lay health advisors, known as Community Health Ambassadors (CHAs), on diabetes-related health behaviors of African Americans living in a public housing …

The American Public’S Perception Of Illegal Steroid Use: A National Survey, 2013, Gary Siperstein, Neil Romano, Gizem Iskenderoglu, Anthony Roman, Floyd J. Fowler Jr., Max Drascher

Center for Social Development and Education Publications

Through the surge of news about doping scandals in the media, it is expected that the public is aware of the magnitude of the problem among professional athletes; however, it is uncertain whether the public is aware that the problem often starts when athletes are younger. To this end, the National Baseball Hall of Fame and Museum, the Taylor Hooton Foundation, and the Professional Baseball Athletic Trainers Society partnered with the Center for Social Development and Education and the Center for Survey Research at the University of Massachusetts Boston to conduct the most comprehensive national opinion survey to date to …

Impact Of Time-Varying And Time-Invariant Measures Of Adherence To Secondary Prevention Therapies Post-Acute Myocardial Infarction: An Application Of Marginal Structural Models (Msms), Tasneem Taher Lokhandwala

Electronic Theses and Dissertations

The purpose of the study was to explore the relationship between patient adherence to secondary prevention therapies post an initial episode of acute myocardial infarction (AMI) and subsequent risk of cardiovascular events by using time-invariant and time-varying measures of adherence. The effectiveness of both measures in predicting a (i) recurrent AMI, and (ii) mortality using various mathematical models and statistical techniques was compared. Time dependent confounding was accounted for by using marginal structural models (MSMs). A longitudinal cohort observational study design was employed using the retrospective Medicare 5% random national sample claims data from January 1st, 2006 to December 31st, …

A Neurophysiological Examination Of Stress Control In Martial Artists, Jack Pemment

Electronic Theses and Dissertations

The philosophies behind many martial arts often claim that by practicing martial arts individuals can gain better control over stress. We tested this idea by using controlled physical stressors to elicit an acute stress response from martial artists (n=15) and non-martial artists (n=18). To measure the extent of the stress response, we looked at changes in heart rate, respiratory sinus arrhythmia, and galvanic skin level. These three measures explore both parasympathetic and sympathetic responses, and changes in these variables continue to be explored in studies of stress and reactive aggression. In addition to our physical stressors we also exposed individuals …