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2013

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Articles 5101 - 5130 of 7931

Full-Text Articles in Medicine and Health Sciences

Nutrient Intake In The Geico Multicenter Trial: The Effects Of A Multicomponent Worksite Intervention, S. Mishra, Neal D. Barnard, J. Gonzales, J. Xu, U. Agarwal, S. Levin Jan 2013

Nutrient Intake In The Geico Multicenter Trial: The Effects Of A Multicomponent Worksite Intervention, S. Mishra, Neal D. Barnard, J. Gonzales, J. Xu, U. Agarwal, S. Levin

Medicine Faculty Publications

Background/objectives:

To assess the effects on macro- and micronutrient intake of a nutrition intervention program in corporate settings across the United States.

Subjects/methods:

Two hundred and ninety-two individuals who were overweight or had type 2 diabetes were recruited from 10 sites of a US insurance company. Two hundred and seventy-one participants completed baseline diet recalls, and 183 participants completed dietary recalls at 18 weeks. Sites were randomly assigned to an intervention group (five sites) or to a control group (five sites) for 18 weeks. At intervention sites, participants were asked to follow a low-fat vegan diet and attend weekly group …


Cardiovascular Disease In Women: The Differences In Genders, Kayla Sells Exum Jan 2013

Cardiovascular Disease In Women: The Differences In Genders, Kayla Sells Exum

Graduate Research Projects

No abstract provided.


Telecommuting As The Director Of Clinical Education (Dce) In A Doctoral Physical Therapy Program, Sally Mccormack Tutt Jan 2013

Telecommuting As The Director Of Clinical Education (Dce) In A Doctoral Physical Therapy Program, Sally Mccormack Tutt

Physical Therapy Faculty Posters

Poster describing a case study created to help determine the feasibility of allowing the Director of Clinical Education to telecommute from Florida to Maine as a unique way to retain a valued core faculty member of the DPT department. Concludes there are benefits to departments considering this method of job performance, including: decreasing the turnover of quality faculty at an institution, reducing stress of a vacancy on the department and other faculty, decreasing the cost associated with searching for and hiring a new faculty member, and providing students with consistency with regards to the teaching and advising they receive from …


A Systematic Review Of The Best Practices For Playground Inclusion, Megan Mejeur, Graceann Schmitt, Hannah Wolcott Jan 2013

A Systematic Review Of The Best Practices For Playground Inclusion, Megan Mejeur, Graceann Schmitt, Hannah Wolcott

Pediatrics

Occupational therapy considers the person, occupation, and environment when providing treatment services. In schools, the person is the student, the occupations include education and play, and the environment is the classroom and the playground. In Muskegon, Michigan, the public school system is undergoing a consolidation of elementary schools and trying to determine what to do with the current playground environment. The researchers conducted a systematic review of the existing research regarding best practice, accessible, and inclusive playground designs for the elementary schools that will promote physical activity and enhance classroom performance. Scholarly databases and gray literature were searched using predetermined …


Annual Acknowledgement Of Manuscript Reviewers, Jose Antonio, D. Kalman, R. Kreider Jan 2013

Annual Acknowledgement Of Manuscript Reviewers, Jose Antonio, D. Kalman, R. Kreider

Department of Health and Human Performance Faculty Articles

The editors of Journal of the International Society of Sports Nutrition would like to thank all our reviewers who have contributed to the journal in Volume 9 (2012).


International Society Of Sports Nutrition Position Stand: Betahydroxy- Beta-Methylbutyrate (Hmb), Jacob M. Wilson, Peter J. Fitschen, Bill Campbell, Gabriel J. Wilson, Nelo Zanchi, Lem Taylor, Colin Wilborn, Douglas S. Kalman, Jeffrey R. Stout, Jay R. Hoffman, Tim N. Ziegenfuss, Hector L. Lopez, Richard B. Kreider, Abbie E. Smith-Ryan, Jose Antonio Jan 2013

International Society Of Sports Nutrition Position Stand: Betahydroxy- Beta-Methylbutyrate (Hmb), Jacob M. Wilson, Peter J. Fitschen, Bill Campbell, Gabriel J. Wilson, Nelo Zanchi, Lem Taylor, Colin Wilborn, Douglas S. Kalman, Jeffrey R. Stout, Jay R. Hoffman, Tim N. Ziegenfuss, Hector L. Lopez, Richard B. Kreider, Abbie E. Smith-Ryan, Jose Antonio

Department of Health and Human Performance Faculty Articles

Position Statement: The International Society of Sports Nutrition (ISSN) bases the following position stand on a critical analysis of the literature on the use of beta-hydroxy-beta-methylbutyrate (HMB) as a nutritional supplement. The ISSN has concluded the following. 1. HMB can be used to enhance recovery by attenuating exercise induced skeletal muscle damage in trained and untrained populations. 2. If consuming HMB, an athlete will benefit from consuming the supplement in close proximity to their workout. 3. HMB appears to be most effective when consumed for 2 weeks prior to an exercise bout. 4. Thirty-eight mg·kg·BM-1 daily of HMB has been …


International Society Of Sports Nutrition Position Stand: Energy Drinks, Bill Campbell, Colin Wilborn, Paul La Bounty, Lem Taylor, Mike T. Nelson, Mike Greenwood, Tim N. Ziegenfuss, Hector L. Lopez, Jay R. Hoffman, Jeffrey R. Stout, Stephen Schmitz, Rick Collins, Doug S. Kalman, Jose Antonio, Richard B. Kreider Jan 2013

International Society Of Sports Nutrition Position Stand: Energy Drinks, Bill Campbell, Colin Wilborn, Paul La Bounty, Lem Taylor, Mike T. Nelson, Mike Greenwood, Tim N. Ziegenfuss, Hector L. Lopez, Jay R. Hoffman, Jeffrey R. Stout, Stephen Schmitz, Rick Collins, Doug S. Kalman, Jose Antonio, Richard B. Kreider

Department of Health and Human Performance Faculty Articles

Position Statement: The International Society of Sports Nutrition (ISSN) bases the following position stand on a critical analysis of the literature on the safety and efficacy of the use of energy drinks (ED) or energy shots (ES). The ISSN has concluded the following. 1. Although ED and ES contain a number of nutrients that are purported to affect mental and/or physical performance, the primary ergogenic nutrients in most ED and ES appear to be carbohydrate and/or caffeine. 2. The ergogenic value of caffeine on mental and physical performance has been well-established but the potential additive benefits of other nutrients contained …


Medical Literary Messenger (Vol. 1, No. 1, Fall 2013) Jan 2013

Medical Literary Messenger (Vol. 1, No. 1, Fall 2013)

Medical Literary Messenger

Before the Laying On / Robert Eastwood -- When the Medical Student Teaches / M. Hoya -- Lesion / Stacy R. Nigliazzo -- The Way Back To Childhood / Christopher Woods -- The Uselessness of Our Hands / Sean Prentiss -- Never Forget You Work in Oncology / Lorraine Waltz -- Going Down / Thom Schwarz -- Past Curfew, At a Time Past (1964) / Barbara A. Carrington -- Approaching Shadows / Christopher Woods -- Virginia Nature / Hannah Kim -- Is Six Always Six / Ken Staley -- Cheers (Desvenlafaxine) / Nick D’Annunzio Jones -- Arm Dissection, MCV Gross …


Enhancing Communication Between Scientists, Government Officials, And The Lay Public: Advancing Science And Protecting The Public's Welfare Through Better Multi-Stakeholder Interfacing, Clark J. Lee, Patrick P. Rose, Earl Stoddard Iii Jan 2013

Enhancing Communication Between Scientists, Government Officials, And The Lay Public: Advancing Science And Protecting The Public's Welfare Through Better Multi-Stakeholder Interfacing, Clark J. Lee, Patrick P. Rose, Earl Stoddard Iii

Homeland Security Publications

No abstract provided.


College Of Optometry Overview 2013, Nova Southeastern University Jan 2013

College Of Optometry Overview 2013, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.


Transition Doctor Of Physical Therapy, Nova Southeastern University Jan 2013

Transition Doctor Of Physical Therapy, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.


Physician Assistant Fort Lauderdale 2013, Nova Southeastern University Jan 2013

Physician Assistant Fort Lauderdale 2013, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.


Graduate-Level Nursing Doctor Of Nursing Practice Entering Class 2013, Nova Southeastern University Jan 2013

Graduate-Level Nursing Doctor Of Nursing Practice Entering Class 2013, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.


Santa Clara Magazine, Volume 54 Number 3, Winter 2013, Santa Clara University Jan 2013

Santa Clara Magazine, Volume 54 Number 3, Winter 2013, Santa Clara University

Santa Clara Magazine

16 - TO CATCH A THIEF by Vince Beiser. Mathematician George Mohler has helped equip police in Santa Cruz and L.A. with an algorithm that predicts where crimes might happen next. Is this the future of policing?

22 - HOW TO PREVENT A BONFIRE OF THE HUMANITIES by Michael S. Malone '75, MBA '77. A veteran chronicler of Silicon Valley looks at why the high-tech industry needs-and wants-folks who know how to tell a story.

26 - A POEM, A PRAYER, AND A MARTINI FOR THE RHINO Two conversations with Chancellor William J. Rewak, S.J.-who's just published his first collection …


The State Of The Science Of Health And Wellness For Adults With Intellectual And Developmental Disabilities, Lynda Lahti Anderson, Kathy Humphries, Suzanne Mcdermott, Beth Marks, Jasmina Sisirak, Sheryl Larson Jan 2013

The State Of The Science Of Health And Wellness For Adults With Intellectual And Developmental Disabilities, Lynda Lahti Anderson, Kathy Humphries, Suzanne Mcdermott, Beth Marks, Jasmina Sisirak, Sheryl Larson

Rural Institute Journal Articles

Historically, people with intellectual and developmental disabilities (IDD) have experienced health disparities related to several factors including: a lack of access to high quality medical care, inadequate preparation of health care providers to meet their needs, the social determinants of health (e.g., poverty, race and gender), and the failure to include people with IDD in public health efforts and other prevention activities. Over the past decade, a greater effort has been made to both identify and begin to address myriad health disparities experienced by people with IDD through a variety of activities including programs that address health lifestyles and greater …


Provider Imposed Restrictions To Clients' Access To Family Planning In Urban Uttar Pradesh, India: A Mixed Methods Study, Lisa S. Calhoun, Ilene S. Speizer, Rajiv N. Rimal, Pooja Sripad, Nilesh Chatterjee, Pranita Achyut, Priya Nanda Jan 2013

Provider Imposed Restrictions To Clients' Access To Family Planning In Urban Uttar Pradesh, India: A Mixed Methods Study, Lisa S. Calhoun, Ilene S. Speizer, Rajiv N. Rimal, Pooja Sripad, Nilesh Chatterjee, Pranita Achyut, Priya Nanda

Prevention and Community Health Faculty Publications

Background

Medical barriers refer to unnecessary policies or procedures imposed by health care providers that are not necessarily medically advised; these restrictions impede clients' access to family planning (FP). This mixed methods study investigates provider imposed barriers to provision of FP using recent quantitative and qualitative data from urban Uttar Pradesh, India.

Methods

Baseline quantitative data were collected in six cities in Uttar Pradesh, India from service delivery points (SDP), using facility audits, exit interviews, and provider surveys; for this study, the focus is on the provider surveys. More than 250 providers were surveyed in each city. Providers were asked …


Chhs January 2013 E-Newsletter, Dr. John Bonaguro, Dean, Vashon S. Wells, Editor, Wku College Of Health And Human Services Jan 2013

Chhs January 2013 E-Newsletter, Dr. John Bonaguro, Dean, Vashon S. Wells, Editor, Wku College Of Health And Human Services

College of Health & Human Services Publications

No abstract provided.


Prostate Cancer: Can Multiparametric Mr Imaging Help Identify Patients Who Are Candidates For Active Surveillance?, B. Turkbey, H. Mani, O. Aras, J. Ho, A. Hoang, A. R. Rastinehad, H. Agarwal, V. Shah, M. Bernardo, P. L. Choyke, +8 Additional Authors Jan 2013

Prostate Cancer: Can Multiparametric Mr Imaging Help Identify Patients Who Are Candidates For Active Surveillance?, B. Turkbey, H. Mani, O. Aras, J. Ho, A. Hoang, A. R. Rastinehad, H. Agarwal, V. Shah, M. Bernardo, P. L. Choyke, +8 Additional Authors

Journal Articles

PURPOSE: To determine whether multiparametric magnetic resonance (MR) imaging can help identify patients with prostate cancer who would most appropriately be candidates for active surveillance (AS) according to current guidelines and to compare the results with those of conventional clinical assessment scoring systems, including the D'Amico, Epstein, and Cancer of the Prostate Risk Assessment (CAPRA) systems, on the basis of findings at prostatectomy. MATERIALS AND METHODS: This institutional review board-approved HIPAA-compliant retrospectively designed study included 133 patients (mean age, 59.3 years) with a mean prostate-specific antigen level of 6.73 ng/mL (median, 4.39 ng/mL) who underwent multiparametric MR imaging at 3.0 …


Use Of Desipramine For The Treatment Of Overactive Bladder Refractory To Antimuscarinic Therapy, J. H. Hillelsohn, S. Rais-Bahrami, N. Bagadiya, M. Kashan, G. H. Weiss Jan 2013

Use Of Desipramine For The Treatment Of Overactive Bladder Refractory To Antimuscarinic Therapy, J. H. Hillelsohn, S. Rais-Bahrami, N. Bagadiya, M. Kashan, G. H. Weiss

Journal Articles

Purpose: To evaluate the use of desipramine in the treatment of overactive bladder (OAB). Materials and Methods: We retrospectively evaluated 43 patients who were treated with desipramine for OAB refractory to antimuscarinic therapy. These OAB patients were stratified by the presence or absence of bladder pain. Results: Forty-three patients were evaluated with a mean follow up time of 12.2 +/- 4.6 months. The mean age of the patients was 71 16 years. Twelve patients (28%) discontinued desipramine, 9 due to perceived lack of efficacy, 2 due to central anticholinergic side effects, and 1 due to the development of oropharyngeal sores. …


Comparison Of Endorectal Coil And Nonendorectal Coil T2w And Diffusion-Weighted Mri At 3 Tesla For Localizing Prostate Cancer: Correlation With Whole-Mount Histopathology, B. Turkbey, M. J. Merino, E. C. Gallardo, V. Shah, O. Aras, A. R. Rastinehad, W. M. Linehan, B. J. Wood, P. A. Pinto, P. L. Choyke, +3 Additional Authors Jan 2013

Comparison Of Endorectal Coil And Nonendorectal Coil T2w And Diffusion-Weighted Mri At 3 Tesla For Localizing Prostate Cancer: Correlation With Whole-Mount Histopathology, B. Turkbey, M. J. Merino, E. C. Gallardo, V. Shah, O. Aras, A. R. Rastinehad, W. M. Linehan, B. J. Wood, P. A. Pinto, P. L. Choyke, +3 Additional Authors

Journal Articles

PURPOSE: To compare utility of T2-weighted (T2W) MRI and diffusion-weighted MRI (DWI-MRI) obtained with and without an endorectal coil at 3 Tesla (T) for localizing prostate cancer. MATERIALS AND METHODS: This Institutional Review Board-approved study included 20 patients (median prostate-specific antigen, 8.4 ng/mL). Patients underwent consecutive prostate MRIs at 3T, first with a surface coil alone, then with combination of surface, endorectal coils (dual coil) followed by robotic assisted radical prostatectomy. Lesions were mapped at time of acquisition on dual-coil T2W, DWI-MRI. To avoid bias, 6 months later nonendorectal coil T2W, DWI-MRI were mapped. Both MRI evaluations were performed by …


Understanding The Anatomy Of Dystonia: Determinants Of Penetrance And Phenotype, R. P. Lerner, M. Niethammer, D. Eidelberg Jan 2013

Understanding The Anatomy Of Dystonia: Determinants Of Penetrance And Phenotype, R. P. Lerner, M. Niethammer, D. Eidelberg

Journal Articles

No abstract provided.


The Effects Of Short-Acting Analogue Insulins On Body Weight In Patients With Type 2 Diabetes Mellitus, Cumali̇ Karatoprak, Servet Yolbaş, Muharrem Kiskaç, Mehmet Zorlu, Adnan Yay, Mustafa Çakirca, Mehmetali̇ Çikrikçioğlu, Reha Erkoç, Ertuğrul Taşan Jan 2013

The Effects Of Short-Acting Analogue Insulins On Body Weight In Patients With Type 2 Diabetes Mellitus, Cumali̇ Karatoprak, Servet Yolbaş, Muharrem Kiskaç, Mehmet Zorlu, Adnan Yay, Mustafa Çakirca, Mehmetali̇ Çikrikçioğlu, Reha Erkoç, Ertuğrul Taşan

Turkish Journal of Medical Sciences

To investigate the effects of short-acting analogue insulins on weight, and to demonstrate the difference between analogues. Materials and methods: Our study included patients who have used only intensive insulin therapy with metformin. Those who took other oral antidiabetics, other insulin derivatives, or different insulin combinations were excluded from the study because of the adverse effects on patients' weights. Results: Our study included 118 patients who used insulin glargine with short-acting analogue insulins, i.e. insulin aspart (38 patients), insulin lispro (28 patients), and insulin glulisine (52 patients). After 3 to 6 months of treatment, significant weight gain was observed in …


Improving Dental Care Access For Low-Income Populations, Ethan Jones Jan 2013

Improving Dental Care Access For Low-Income Populations, Ethan Jones

Master of Public Health Program Student Publications

The Surgeon General’s Call to Action report in 2000 established the problem of oral health disparities as an important public health issue. Because of its widespread prevalence and preventable nature, the problem of untreated dental caries and poor oral health has been called a “neglected epidemic.” As in other areas of health, the poor often carry a disproportionate burden of oral health problems. The purpose of this research was to examine the patient population who utilized the dental clinic at the Good Neighbor House, a health and human service organization that serves as a safety net clinic, to determine the …


Air Force Demographics Of Sexually Transmitted Infections 2007 To 2012, Daniel R. Shea Jan 2013

Air Force Demographics Of Sexually Transmitted Infections 2007 To 2012, Daniel R. Shea

Master of Public Health Program Student Publications

In the United States there is a significant gap between Sexually Transmitted Infection (STI) rates of Caucasians and African Americans. This disparity is attributed to many causes including access to health care, socioeconomic status, and social dynamics. The objective of this research is to describe the racial demographics of STI infections in the Air Force and explore possible disparities based on military pay grades. The military enforces many of the recommendations on how to limit STI health disparities by offering easy access to free health care and mandatory regular checkups. Despite these policies, the data reveals significant disparities based on …


Reception Centers In Response To Radiological Hazards: Correctly Triaging Survivors, Ameer Matariyeh Jan 2013

Reception Centers In Response To Radiological Hazards: Correctly Triaging Survivors, Ameer Matariyeh

Master of Public Health Program Student Publications

A disastrous incident involving radiological materials has the potential to cause mass casualties exceeding several thousand. Early diagnostic screening and triage at community reception centers (CRC) are excellent tools to keep communities safe from unidentified radiological material. Community receptionists quickly screen survivors with portable radiation detectors before triaged first aid survivors are transported to a nearby hospital. Screening for radiation immediately upon arrival to a community reception center reduces internal and external radiation dose levels, as well as the chance of chronic radiation illness. This culminating experience sought to determine if different CRC flow charts affect survivor triage.


Perception Of Slipperiness And Prospective Risk Of Slipping At Work, Theodore K. Courtney, Santosh K. Verma, Wen-Ruey Chang, Yueng-Hsiang Huang, David A. Lombardi, Melanye J. Brennan, Melissa J. Perry Jan 2013

Perception Of Slipperiness And Prospective Risk Of Slipping At Work, Theodore K. Courtney, Santosh K. Verma, Wen-Ruey Chang, Yueng-Hsiang Huang, David A. Lombardi, Melanye J. Brennan, Melissa J. Perry

Environmental and Occupational Health Faculty Publications

Objectives: Falls are a leading cause of injury at work, and slipping is the predominant cause of falling. Prior research has suggested a modest correlation between objective measures (such as coefficient of friction, COF) and subjective measures of slipperiness (such as worker perceptions) in the workplace. However, the degree of association between subjective measures and the actual risk of slipping at the workplace is unknown. This study examined the association between perception of slipperiness and the risk of slipping.

Methods: 475 workers from 36 limited-service restaurants participated in a 12-week prospective cohort study. At baseline, demographic information was collected, participants …


Treatment-As-Prevention In Aids Control: Why Communication Still Matters, Rupali J. Limaye, Jeffrey Bingenheimer, Rajiv N. Rimal, Susan Krenn, Claudia Vondrasek Jan 2013

Treatment-As-Prevention In Aids Control: Why Communication Still Matters, Rupali J. Limaye, Jeffrey Bingenheimer, Rajiv N. Rimal, Susan Krenn, Claudia Vondrasek

Prevention and Community Health Faculty Publications

Treatment-as-prevention is a term used to describe an HIV prevention method that uses antiretroviral treatment to minimize the chance of HIV transmission, with the idea that treatment can decrease the viral load of those infected to a level where transmission risk is minimal. However, for treatment-as-prevention to be a success, individuals must get tested, know their status, seek care, and adhere to their antiretroviral regimen. Communication plays a role in each of these steps, as communication can be used to create demand for health-seeking behavior and as a means to increase quality and support on the supply side, at the …


Development And Assessment Of Traditional And Innovative Media To Reduce Individual Hiv/Aids-Related Stigma Attitudes And Beliefs In India, Caricia Catalani, Diego Castaneda, Freya Spielberg Jan 2013

Development And Assessment Of Traditional And Innovative Media To Reduce Individual Hiv/Aids-Related Stigma Attitudes And Beliefs In India, Caricia Catalani, Diego Castaneda, Freya Spielberg

Prevention and Community Health Faculty Publications

Although stigma is considered a major barrier to effective response to the HIV/AIDS epidemic, there is a lack of evidence on effective interventions. This media intervention took place among key HIV-vulnerable communities in Southern India. Two HIV stigma videos were created using techniques from traditional film production and new media digital storytelling. A series of 16 focus group discussions were held in 4 rural and 4 urban sites in South India, with specific groups for sex workers, men who have sex with men, young married women, and others. Focus groups with viewers of the traditional film (8 focus groups, 80 …


A Quantitative Link Between Face Discrimination Deficits And Neuronal Selectivity For Faces In Autism, Xiong Jiang, Angela Bollich, Patrick Cox, Eric Hyder, Joette James, Saqib Ali Gowani, Nouchine Hadjikhani, Volker Blanz, Dara S. Manoach, Jason J.S. Barton, William D. Gaillard, Maximilian Reisenhuber Jan 2013

A Quantitative Link Between Face Discrimination Deficits And Neuronal Selectivity For Faces In Autism, Xiong Jiang, Angela Bollich, Patrick Cox, Eric Hyder, Joette James, Saqib Ali Gowani, Nouchine Hadjikhani, Volker Blanz, Dara S. Manoach, Jason J.S. Barton, William D. Gaillard, Maximilian Reisenhuber

Psychiatry and Behavioral Sciences Faculty Publications

Individuals with Autism Spectrum Disorder (ASD) appear to show a general face discrimination deficit across a range of tasks including social–emotional judgments as well as identification and discrimination. However, functional magnetic resonance imaging (fMRI) studies probing the neural bases of these behavioral differences have produced conflicting results: while some studies have reported reduced or no activity to faces in ASD in the Fusiform Face Area (FFA), a key region in human face processing, others have suggested more typical activation levels, possibly reflecting limitations of conventional fMRI techniques to characterize neuron-level processing. Here, we test the hypotheses that face discrimination abilities …


Association Between The Luteinizing Hormone/Chorionic Gonadotropin Receptor (Lhcgr) Rs4073366 Polymorphism And Ovarian Hyperstimulation Syndrome During Controlled Ovarian Hyperstimulation, Travis J. O'Brien, Mariah M. Kalmin, Arthur F. Harralson, Adam M. Clark, Ian Gindoff, Samuel J. Simmens, David Frankfurter, Paul Gindoff Jan 2013

Association Between The Luteinizing Hormone/Chorionic Gonadotropin Receptor (Lhcgr) Rs4073366 Polymorphism And Ovarian Hyperstimulation Syndrome During Controlled Ovarian Hyperstimulation, Travis J. O'Brien, Mariah M. Kalmin, Arthur F. Harralson, Adam M. Clark, Ian Gindoff, Samuel J. Simmens, David Frankfurter, Paul Gindoff

Pharmacology and Physiology Faculty Publications

Background

The aim of this study was to determine the relationship between a purported luteinizing hormone/chorionic gonadotropin (LHCGR) high function polymorphism (rs4539842/insLQ) and outcome to controlled ovarian hyperstimulation (COH).

Methods

This was a prospective study of 172 patients undergoing COH at the Fertility and IVF Center at GWU. DNA was isolated from blood samples and a region encompassing the insLQ polymorphism was sequenced. We also investigated a polymorphism (rs4073366 G > C) that was 142 bp frominsLQ. The association of the insLQ and rs4073366 alleles and outcome to COH (number of mature follicles, …