Medicine and Health Sciences Commons^™

Accelerating And Expanding Knowledge Transfer In Public Health Settings: Frontiers In Phssr, Glen P. Mays

Health Management and Policy Presentations

Creating a "rapid-learning" system in public health requires mechanisms for the continuous exchange of knowledge and evidence among researchers, practice settings, and policy decision-makers. The open-access platform Frontiers in Public Health Services and Systems Research provides a new mechanism for this exchange.

Expansion Of Breast Cancer Stem Cells With Fibrous Scaffolds, Sheng Feng, Pang-Kuo Lo, Shou Liu, Xinfeng Liu, Hexin Chen, Qian Wang

Faculty Publications

Cancer stem cells (CSCs) are hypothesized as tumor-initiating cells within tumors and main contributors of tumor growth, metastasis and recurrence. Mammary cancer cells, MCF-7 cells, were cultured on 3D polycaprolactone (PCL) fibrous scaffolds, showing an increased proportion of CSCs. The expression of stem cell markers, including OCT3/4 and SOX2, and breast CSC-specific markers, SOX4 and CD49f, was significantly upregulated, and the mammosphere-forming capability in cells cultured on PCL fibrous scaffolds increased. The fibrous scaffolds also induced the elongation of MCF-7 cells and extended cell proliferation. The increase of CSC properties after being cultured on fibrous scaffolds was further confirmed with …

Two-Legged Hopping In Autism Spectrum Disorders, Matthew F. Moran, John T. Foley, Mary E. Parker, Michael J. Weiss

All PTHMS Faculty Publications

Sensory processing deficits are common within autism spectrum disorders (ASD). Deficits have a heterogeneous dispersion across the spectrum and multimodal processing tasks are thought to magnify integration difficulties. Two-legged hopping in place in sync with an auditory cue (2.3, 3.0 Hz) was studied in a group of six individuals with expressive language impaired ASD (ELI-ASD) and an age-matched control group. Vertical ground reaction force data were collected and discrete Fourier transforms were utilized to determine dominant hopping cadence. Effective leg stiffness was computed through a mass-spring model representation. The ELI-ASD group were unsuccessful in matching their hopping cadence (2.21 ± …

Existing Evidence Of The Business Case For Investments In Nursing Care, Olga Yakusheva, Douglas Wholey, Kevin D. Frick

Economics Faculty Research and Publications

No abstract provided.

Substance Abuse And Insecure Attachment Styles: A Relational Study, Yasmin Borhani

LUX: A Journal of Transdisciplinary Writing and Research from Claremont Graduate University

The attachment styles an individual forms while they are growing up can impact the type of relationships they form as adults. Research has shown insecure attachment styles can be correlated to substance abuse, emotional distress, and interpersonal problems. More specifically, this study focuses on the correlation between insecure attachment styles and substance abuse. Nineteen participants (nine male, ten female) between the ages of 18 to 32 were selected. Participants were given a 20-question survey that measured substance abuse and attachment styles. A t-test was conducted to compare the differences between participants who abuse substances and participants who do not abuse …

Neurosurgery Concepts: Key Perspectives On Regulatory Proteins, Management Of Ossification Of The Posterior Longitudinal Ligament, And Radiosurgery For Intracranial Lesions, Jonathan H. Sherman, Zachary A. Smith, Jin Mo Cho, Michael Lim, Chaim B. Colen, Chae-Yong Kim, Vincent Yat Wang, Gabriel Zada, Gordon Li, Isaac Yang

Neurological Surgery Faculty Publications

No abstract provided.

Smoking Abstinence-Related Expectancies Among American Indians, African Americans, And Women: Potential Mechanisms Of Disparities In Cigarette Use, P. S. Hendricks, J. L. Westmaas, Van M. Ta Park, C. B. Thorne, S. B. Wood, M. R. Baker, M. R. Lawler, M. Webb Hooper, K. L. Delucchi, S. M. Hall

Faculty Publications

Research has documented tobacco-related health disparities by race and gender. Prior research, however, has not examined expectancies about the smoking cessation process (i.e., abstinence-related expectancies) as potential contributors to tobacco-related disparities in special populations. This cross-sectional study compared abstinence-related expectancies between American Indian (n = 87), African American (n = 151), and White (n = 185) smokers, and between women (n = 231) and men (n = 270) smokers. Abstinence-related expectancies also were examined as mediators of race and gender relationships with motivation to quit and abstinence self efficacy. Results indicated that American Indians and African Americans were less likely …

Children First: It’S Time To Change! Mental Health Promotion, Prevention, And Treatment Informed By Public Health, And Resiliency Approaches, Vicki Schwean, Susan Rodger

Journal Articles

Although the importance of healthy mental development in children and youth is not disputed, the mental health needs of far too many Canadian children are being ignored. Within the context of recent federal and provincial calls for systemic reform of the mental health care systems for children and youth, we underscore the necessity for ongoing innovation, development, education, and evaluation. This article describes our aims to establish demonstration and research sites focused on promising frameworks that draw from systems of care, public health, and resiliency approaches.

What's Happening: March 25, 2013, Maine Medical Center

What's Happening

No abstract provided.

Scoring Rubrics: Educators Tools To Facilitate Student Learning,, Mary Hanson-Zalot, Kathleen Day

Tech Talks

This session will focus on the creation and implementation of scoring rubrics. Basic rubric construction will be presented along with discussion of rubric functions for varying levels of students. Some information on the use of rubrics in the new Blackboard system will follow.

13 PowerPoint slides

Pelayanan Kesehatan Ibu Dan Kematian Neonatal, Desy Fitri Yani, Artha Budi Susila Duarsa

Kesmas

Indonesia bersama seluruh negara berkembang berupaya mencapai kesepakatan Millenium Development Goals (MDGs) dengan salah satu sasaran menurunkan angka kematian neonatal dari 20 per 1.000 kelahiran hidup menjadi 15 per 1.000 kelahiran hidup. Penelitian ini bertujuan mengetahui hubungan pelayanan kesehatan ibu dengan kematian neonatal di Kabupaten Lampung Timur tahun 2011. Penelitian dengan desain studi kasus kontrol ini mengamati kasus ibu yang mengalami kematian neonatal dan kontrol ibu yang tidak mengalami kematian neonatal. Analisis multivariat menemukan pelayanan antenatal dan pertolongan persalinan berhubungan secara signifikan dengan kematian neonatal, setelah mengendalikan variabel umur ibu dan riwayat kehamilan (OR = 16,32; nilai p = 0,000); …

Peranan Moderasi Soft Skills Dalam Meningkatkan Mutu Pelayanan Rumah Sakit, Viviyanti Azwar

Kesmas

Penurunan mutu pelayanan Rumah Sakit Umum Pusat Dr. M. Djamil merupakan penentu bagi kinerja rumah sakit sebagai perusahaan jasa. Penurunan mutu pelayanan diindikasikan dengan penurunan rata-rata pelayanan periode tahun 2008-2010 pada instalasi radiologi mencapai 11,29%, laboratorium 5,19%, farmasi 18,5%, instalasi rehabilitasi medik 3,74%, gizi 9,12%, pemulasan jenazah 11,86%, operasi 5,29%, dan hemodialisa 3,62%. Penelitian ini bertujuan untuk menganalisis peranan soft skills memoderasi sumber daya organisasi, keterikatan kerja, kinerja karyawan dalam meningkatkan mutu pelayanan rumah sakit. Pengukuran seluruh konstruksi dan indikator penelitian menggunakan kuesioner yang disebarkan kepada 530 karyawan rumah sakit sebagai tenaga medis maupun nonmedis yang dijadikan responden. Metode analisis …

Speech-Language Pathoogists' Practices & Perspectives Pertaining To Animal-Assisted Therapy, Jessica S. Popp

Theses & Honors Papers

Purpose: The precise beneficial role of animals to serve as facilitators or incentives for human communication has received limited attention to date in the field of communication sciences and disorders (CSD). This study addresses the need within the field of communication sciences and disorders for qualitative research that focuses on the use of animal-assisted therapy (AAT) by speech-language pathologists . The researcher aimed to answer the following research question: What are speech-language pathologists' practices and perspectives pertaining to animal-assisted therapy? The researcher hypothesizes that the data from this survey research study will indicate patterns worth further analysis through single subject …

Network Firewall Dynamics And The Subsaturation Stabilization Of Hiv, Bilal Khan, Kirk Dombrowski, Mohamed Saad, Katherine Mclean, Samuel Friedman

Publications and Research

In 2001, Friedman et al. conjectured the existence of a “firewall effect” in which individuals who are infected with HIV, but remain in a state of low infectiousness, serve to prevent the virus from spreading. To evaluate this historical conjecture, we develop a new graph-theoreticmeasure that quantifies the extent towhich Friedman’s firewall hypothesis (FH) holds in a risk network.We compute this new measure across simulated trajectories of a stochastic discrete dynamical system that models a social network of 25,000 individuals engaging in risk acts over a period of 15 years. The model’s parameters are based on analyses of data collected …

Analysis Of Goals Scored In The 2010 World Cup Soccer Tournament Held In South Africa, Wycliffe W. Njororai Simiyu

Health & Kinesiology Faculty Publications and Presentations

Purpose: To analyze the pattern and trends of the goals scored during the 2010 world cup soccer tournament held in South Africa to derive the latest technical and tactical innovations with the hope of applying them at the lower echelons of the game. Methodology: The study was a retrospective one as data were derived from the FIFA (2010) data base. The analysis centered on number of goals; parts of the body used to score; distance from goal; timing of goals in minutes; nature of play preceding a goal; score at half time and winning of the game; open play and …

Model Prediksi Berat Lahir Bayi Berdasarkan Berat Badan Ibu Hamil, Maulia Sari, Trini Sudiarti

Kesmas

Berat lahir bayi kurang dari 3.000 gram berisiko untuk terjadinya penyakit jantung dan stroke serta kematian yang tiga belas persen lebih tinggi daripada berat lahir lebih dari 3000 gram. Tujuan penelitian ini yaitu untuk mendapatkan model prediksi berat lahir dan mengetahui faktor yang paling berpengaruh terhadap berat lahir bayi. Desain penelitian menggunakan cohort retrospektif. Sampel melibatkan 233 ibu hamil beserta bayi yang melakukan pemeriksaan antenatal care dan melahirkan di Rumah Sakit Citra Medika dan bidan bersalin Hj. Sumartini dari bulan Januari 2010 sampai Desember 2011 di Rantauprapat. Data dikumpulkan dari data rekam medis dan kelahiran pasien. Analisis korelasi dan regresi …

Persepsi, Peluang Aksi, Dan Infomasi Serta Perilaku Pencegahan Malaria, Elviera Gamelia, Siwi Pramatama Mars Wijayanti

Kesmas

Di dunia, malaria masih menjadi masalah kesehatan masyarakat terutama di negara-negara tropis termasuk Indonesia. Di Jawa Tengah, kasus malaria terus memperlihatkan kecenderungan yang meningkat, salah satu daerah endemis malaria di Banyumas adalah Puskesmas II Sumpiuh. Berdasarkan survei pendahuluan masih banyak ditemukan perilaku berisiko yang dapat mengakibatkan terjadi malaria. Penelitian ini bertujuan mengetahui persepsi masyarakat, kemungkinan aksi, dan informasi tentang malaria yang berpengaruh terhadap perilaku pencegahan malaria di Puskesmas Sumpiuh II Banyumas. Penelitian observasional dengan pendekatan cross sectional ini dilakukan pada populasi kepala keluarga di Puskesmas II Sumpiuh. Jumlah sampel sebanyak 95 kepala keluarga ditarik menggunakan metode simple random sampling. Pengumpulan …

Kehamilan Yang Tidak Diinginkan Dan Berat Badan Lahir Bayi, Devinita Ayu Nurcahyani, Indang Trihandini

Kesmas

Berat badan lahir dianggap faktor penentu yang paling penting dari kesehatan dan kelangsungan hidup anak. Penelitian ini bertujuan untuk mempelajari besar risiko kehamilan tidak diinginkan terhadap berat bayi berdasarkan persepsi ibu di Indonesia tahun 2010 beserta faktor-faktor perancunya. Penelitian ini merupakan penelitian analitik dengan menggunakan data sekunder dari Riset Kesehatan Dasar tahun 2010. Namun, studi ini memiliki variabel dari hasil kehamilan sehingga memungkinkan menggunakan desain penelitian kohort retrospektif. Berdasarkan hasil analisis multivariat ditemukan bahwa ibu yang mengalami kehamilan tidak diinginkan berisiko melahirkan bayi dengan berat badan lahir rendah (BBLR) yang didasarkan pada persepsi ibu sekitar 1,27 kali lebih besar daripada …

Penentu Kecepatan Pengeluaran Air Susu Ibu Setelah Sectio Caesarea, Desmawati Desmawati

Kesmas

Pengeluaran air susu ibu (ASI) secara dini adalah syarat penting dalam mendukung pemberian ASI eksklusif. Pengeluaran ASI pada ibu post sectio caesarea sedikit lebih lambat dibanding dengan ibu post partum normal. Tujuan penelitian untuk mengetahui pengaruh posisi menyusui, nyeri setelah sectio caesarea, mobilisasi, rooming in, dan rolling massage terhadap kecepatan pengeluaran ASI pada ibu post sectio caesarea. Populasi penelitian dengan metode cross sectional ini adalah ibu-ibu post sectio caesarea yang berjumlah 90 orang. Hasil penelitian menunjukkan ada hubungan posisi menyusui, nyeri setelah sectio caesarea, mobilisasi aktif, rooming in kontinu, dan intervensi rolling massage dengan kecepatan waktu pengeluaran ASI pada ibu …

Flagellar Motility Is A Key Determinant Of The Magnitude Of The Inflammasome Response To Pseudomonas Aeruginosa, Yash R. Patankar, Rustin R. Lovewell, Matthew E. Poynter, Jeevan Jyot, Barbara I. Kazmierczak, Brent Berwin

Dartmouth Scholarship

We previously demonstrated that bacterial flagellar motility is a fundamental mechanism by which host phagocytes bind and ingest bacteria. Correspondingly, loss of bacterial motility, consistently observed in clinical isolates from chronic Pseudomonas aeruginosa infections, enables bacteria to evade association and ingestion of P. aeruginosa by phagocytes both in vitro and in vivo. Since bacterial interactions with the phagocyte cell surface are required for type three secretion system-dependent NLRC4 inflammasome activation by P. aeruginosa, we hypothesized that reduced bacterial association with phagocytes due to loss of bacterial motility, independent of flagellar expression, will lead to reduced inflammasome activation. Here we report …

The Role Of Nicotinic Acetylcholine Receptors In Ethanol Responsive Behaviors And Drinking, Anton Dawson

Theses and Dissertations

The high co-morbidity between alcohol (ethanol) and nicotine abuse suggests that nicotinic acetylcholine receptors (nAChRs), which are thought to underlie nicotine dependence, may also be involved in alcohol dependence. A genomic region that encodes the Alpha5* nAChR subtype has recently been shown to be associated with alcohol dependence phenotypes in humans. Therefore, the aim of this study was to determine the role of Alpha5* nAChRs in ethanol-responsive behaviors upon acute administration in mice as well as in their drinking behavior. We conducted tests in mice lacking the Alpha5 coding gene (Chrna5) in ethanol-induced hypothermia, hypnosis, anxiolysis, and conditioned place preference. …

Tgf-Beta Suppresses Vegfa-Mediated Angiogenesis In Colon Cancer Metastasis., Liying Geng, Anathbandhu Chaudhuri, G. Talmon, James L. Wisecarver, J. Wang

Journal Articles: Eppley Institute

The FET cell line, derived from an early stage colon carcinoma, is non-tumorigenic in athymic nude mice. Engineered FET cells that express TGF-α (FETα) display constitutively active EGFR/ErbB signaling. These cells readily formed xenograft tumors in athymic nude mice. Importantly, FETα cells retained their response to TGF-beta-mediated growth inhibition, and, like the parental FET cells, expression of a dominant negative TGF-beta type II receptor (DNRII) in FETα cells (FETα/DNRII) abrogated responsiveness to TGF-beta-induced growth inhibition and apoptosis under stress conditions in vitro and increased metastatic potential in an orthotopic model in vivo, which indicates metastasis suppressor activity of TGF-beta signaling …

Medical School Watercooler Newsletter - March 24, 2013, Lindsey Lyle

Watercooler Newsletter

This is the March 24, 2013 edition of the Frederick P. Whiddon College of Medicine's newsletter, watercooler.

Contents Include

• USA Mitchell Cancer Institute Launches New Website
• April 4th DSS to Feature Dr. Lorraine Ware
• USA Welcomes Practice Director of Surgery
• Med School Café - Expert Advice for the Community

Sweet Freedom: Smokers’ Rights & The Rebranding Of Philip Morris, Amy Dipierro

Annual Undergraduate Conference on Health and Society

This paper discusses how Philip Morris invoked strong American values to defend its own corporate speech as well as “smoker’s rights.” In particular, it examines Philip Morris Company’s Bill of Rights advertising campaign of the early 1990s, especially focusing on an advertisement featuring Everett Alvarez, a prisoner of war during Vietnam. This strategy reveals how Philip Morris was able to manipulate the public conversation about smoking from one about health and disease to one about human rights and freedoms.

43rd Annual Wku Student Research Conference, Student Research Council, Western Kentucky University

Student Research Conference Select Presentations

No abstract provided.

Pit Latrines And Their Impacts On Groundwater Quality: A Systematic Review, Jay P. Graham, Matthew L. Polizzotto

Environmental and Occupational Health Faculty Publications

Background: Pit latrines are one of the most common human excreta disposal systems in low-income countries, and their use is on the rise as countries aim to meet the sanitation-related target of the Millennium Development Goals. There is concern, however, that discharges of chemical and microbial contaminants from pit latrines to groundwater may negatively affect human health.

Objectives: Our goals were to a) calculate global pit latrine coverage, b) systematically review empirical studies of the impacts of pit latrines on groundwater quality, c) evaluate latrine siting standards, and d) identify knowledge gaps regarding the potential for …

Prevalence And Correlates Of Depression Among Chronic Kidney Disease Patients In Taiwan, Hsin-Hung Chiang, Hanoch Livneh, Mei-Ling Yen, Tsai-Chung Li, Tzung-Yi Tsai

Counselor Education Faculty Publications and Presentations

Background: Chronic kidney disease (CKD) is a progressive disease that causes a permanent impairment of renal function and premature mortality. The associated prognosis may result in serious psychological distress to the affected individual. However, there are limited data on the psychological correlates, and in particular depression, in Chinese CKD patients. This study aimed to examine the prevalence of depression, as well as the influence of other psychosocial factors on depression, among Taiwanese CKD patients.

Methods: We used a cross-sectional research design to recruit 270 CKD patients who were not undergoing dialysis treatment at a hospital in southern Taiwan during 2011. …

The Stethoscoop, April 24, 2013, Mennonite College Of Nursing

The Stethoscoop

The Stethoscoop is the newsletter for Mennonite College of Nursing students.

College Of Public Health News, Georgia Southern University

College of Public Health: News & Publications

• Luque Reviews Practice Modes

Overweight And Obesity In Kaoma And Kasama Rural Districts Of Zambia: Prevalence And Correlates In 2008-2009 Population Based Surveys, Chola Besa, David Mulenga, Olesegun Babaniyi, Peter Songolo, Adamson S. Muula, Emmanuel Rudatsikira, Seter Siziya

Faculty Publications

Background: Overweight and obesity (overweight/obesity) is associated with hypertension. Low- and middleincome countries are experiencing an obesity epidemic. There is growing evidence that the epidemic is on the increase in urban settings of developing countries. However, there is scanty information on the magnitude of this epidemic and its correlates in rural settings. The objective of the current study was to establish levels of overweight/obesity and its correlates in rural areas of Zambia. Designing interventions based on the correlates for overweight/obesity to reduce its prevalence may in turn lead to a reduction in the prevalence of hypertension.

Methods: Cross sectional studies …