Medicine and Health Sciences Commons^™

Quality Improvement Project: Analysis Of Efficiency Of Current Order Set For The Diagnostic Workup Used To Evaluate Neurogenic Stress Myocardium In Aneurysmal Subarachnoid Hemorrhage, Denise Miller Niklasch, Kathleen Bobay

College of Nursing Faculty Research and Publications

Purpose

To evaluate patterns of utilization of the aneurysmal subarachnoid hemorrhage (aSAH) protocol order set for neurogenic stress myocardium (NSM).

Data sources

Retrospective chart review.

Conclusions

The results of this study demonstrate that protocol order sets can be prone to omissions, variations in practice, and delays.

Implications for practice

Education and implementation of an intervening compliance monitor are essential to improve utilization and correctness in use of the aSAH protocol order set for NSM. Advance practice nurses (APNs) or nursing staff could provide this service. This would improve teamwork, improve efficiency of care delivery and utilization of resources, promote leadership …

Correlates Of Diarrhoea Among Children Below The Age Of 5 Years In Sudan, Seter Siziya, Adamson S. Muula, Emmanuel Rudatsikira

Faculty Publications

Background

The Millennium Development Goals recognise child health and survival as an important socio-development issue.

Objectives

To determine the correlates of diarrhoea among children aged below 5 years in north Sudan.

Methods

We conducted secondary data analysis of the Sudan Multiple Cluster Indicators Survey II.

Results

Altogether, 23,295 children were included in the survey. Half (50.0%) of the children were males, and 22.5% of them were of age less than one year. Boys were 3% (p=0.044) more likely to have diarrhoea compared to girls. Compared with the oldest age group (48–59 months), children less than 6 months of age and …

Prevalence And Predictors Of Smoking In A Mining Town In Kitwe, Zambia: A 2011 Population-Based Survey, Cosmas Zyaambo, Olesegun Babaniyi, Peter Songolo, Adamson S. Muula, Emmanuel Rudatsikira, Seter Siziya

Faculty Publications

Smoking is one of the major preventable causes of death and non-communicable diseases which include hypertension, cardiovascular diseases and cancers. The aim of the study is to establish prevalence and predictors of smoking so that interventions specific to these communities can be executed to prevent smoking. A cross sectional study was conducted using a modified World Health Organizations Global Non Communicable Diseases (NCD) Surveillance Initiative NCD-STEPs 1 and 2. Multivariate logistic regression was used to examine the determinants of tobacco smoking. A total of 1627 individuals participated in the survey, of which 42.3% were males. About half of the participants …

Leisure-Time Physical Activity In Relation To Depressive Symptoms In African-Americans: Results From The National Survey Of American Life, Elisa R. Torres, Carolyn M. Sampselle, David L. Ronis, Harold W. Neighbors, Kimberlee A. Gretebeck

College of Nursing Faculty Research and Publications

Objective

To examine the frequency of leisure-time physical activity (LTPA) in relation to depressive symptoms in a nationally representative sample of African American (AA) women and AA men with guidance by Stokols' Social Ecological Framework.

Method

A secondary analysis of AA women (n = 1811) and AA men (n = 1038) was performed on the National Survey of American Life, where a four stage national area probability sampling was conducted. Interviews were conducted 2001–2003. Clinically depressed AA were excluded from the current study. LTPA was measured by self-report frequency (never, rarely, sometimes, often) of participation in sports/exercise. Depressive symptoms were …

Role Of Smarcad1 In Human Breast Cancer Cell Proliferation, Colony Growth, Migration And Invasion, Elham M. Al-Kubaisy

Theses

Breast cancer is the most common cancer seen in women worldwide accounting for more than 1.3 million cases and 458 000 deaths a year worldwide. Breast cancer patients are at high risk of recurrence in the form of metastatic disease. Genes associated with invasion and metastasis provides an aggressive edge in proliferation and growth during colonization of the metastatic site. The SMARCAD1 (SWI/SNF-related, Matrix-associated, Actin-dependent Regulator of Chromatin, containing DEAD/H box 1) protein is the human homolog of yeast Fun30 (Function Unknown Now 30) proteins. These proteins are members of the Snf2 helicase motif-containing protein families, and are known to …

Session 4-2-A: Taking The Disorder Out Of Gambling Disorder, Denise F. Quirk, Colin M. Hodgen

International Conference on Gambling & Risk Taking

DSM‐5 Gambling Disorder

A. Persistent and recurrent problematic gambling behavior leading to clinically significant impairment or distress, as indicated by four (or more) of the following in a 12‐month period:

A. Persistent and recurrent maladaptive gambling behavior as indicated by five (or more) of the following:

Session 4-2-C: Does Non-Problem Gaming Have Any Negative Impact On Gamblers?, Samuel Huang

International Conference on Gambling & Risk Taking

Outline

Background

Literature Review

Data and Methodology

Analysis and Discussion

Session 4-1-D: The Experience Of Lotto 6/49 And The Capacity To Trust: Elements For An Anthropology Of Gambling, Jocelyn Gadbois

International Conference on Gambling & Risk Taking

Anthropologists study Lotto 6/49 as an experience.

Lévy-Bruhl tries to compare the magical beliefs of serious gamblers with the magical beliefs of individuals he refers to as the ‘‘primitives’’ (1924).

After that, Henslin studied the superstitions of St.Louis taxi drivers who play craps during their work breaks and compared them to Skinner’s pigeon (1967).

I wanted in my thesis to help anthropology to reconstruct lost knowledge regarding gambling and beliefs about magic in capitalist society.

Session 4-1-C: Social Gaming: Problems, Policies And Predictions, Keith Whyte

International Conference on Gambling & Risk Taking

Discusses key issues with social gaming.

Session 4-1-A: Roman Addiction: The Changing Perception Of Problem Gaming In The Roman World, Suzanne B. Faris

International Conference on Gambling & Risk Taking

Describes the perception of problem gambling in ancient Rome.

Session 4-1-C: Social Media Gambling Games: Impact On Young People, Sally Gainsbury, Jeffrey L. Derevensky

International Conference on Gambling & Risk Taking

Key concerns for youth

Normalisation & positive impressions of gambling

Misrepresenting the odds of winning

Encouraging transition to real money gambling

Development of problems

Session 4-1-A: The Problem Gambling Center, Robert Hunter

International Conference on Gambling & Risk Taking

Provides information and statistics on the Problem Gambling Center.

Strangling Of Patient In Nursing Home A Shuddering Reminder Of Subpar Care For Huntington's Disease, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.

Hollow Fiber Membrane-Based Air Gap Membrane Distillation, Xuan Wang

Theses

Membrane Distillation (MD) is a thermally-driven separation process. In this research, desalination of 1 % NaCl solution is achieved by one type of MD namely, Air Gap Membrane Distillation (AGMD). The characteristics of AGMD are evaluated by using a hollow-fiber-set-based compact device. Hot brine solution and cold water are passed through two different fiber sets separately: porous hydrophobic polyvinylidene fluoride hollow fibers of the E type (PVDF E) and solid polypropylene (PP) hollow fibers. Vapor from the hot brine crosses the membrane pores of the PVDF fibers and the air gap, and finally condenses over the surface of solid hollow …

Engineering Spores To Display G Protein-Coupled Receptors For Directed Evolution, Alyssa Misoo Kim

Theses

All human cells are surrounded by a plasma membrane made from a phospholipid bilayer, which is responsible for maintaining a biologically active species, while stopping entry of deleterious substances from the outside. G protein-coupled receptors (GPCRs) are the membrane proteins, which transmit signals across the cell membrane. GPCRs are involved in almost every physiological process, and irregular control leads to pathological conditions. Therefore, they are major drug targets. Crystal structure determination is required to understand the molecular details of activation/deactivation. However, GPCRs are difficult to crystallize because of stability issues. An efficient protein engineering system needs to be developed. The …

Effect Of Tablet Compression On The Dissolution Of Aspirin Tablets Using A Novel Off-Center Paddle Impeller (Opi) Dissolution Testing System, Chuan Sun

Theses

In the pharmaceutical industry, dissolution testing is routinely carried out to determine the dissolution rate of oral solid dosage forms. Among several testing devices, the USP Dissolution Apparatus 2 is the device most commonly used. However, despite its widespread use, this apparatus has been shown to produce test failures and to be very sensitive to a number of small geometry changes.

The objective of this study was to determine whether a novel dissolution system termed “OPI” for “off-center paddle impeller” was sensitive enough to determine differences in tablet dissolution profiles caused by different compression pressure during the tablet manufacturing process. …

Dissolution Of Different Commercial Aspirin Tablets Using A Novel Off-Center Paddle Impeller (Opi) Dissolution Testing System, Yang Qu

Theses

Dissolution testing is routinely conducted in the pharmaceutical industry to provide in vitro drug release information for quality control purposes. The most common dissolution testing system for solid dosage forms is the United States Pharmacopeia (USP) Dissolution Testing Apparatus 2. In this work, a modified Apparatus 2, termed "OPI" System for "off-center paddle impeller," in which the impeller is placed 8 mm off center in the vessel is tested to determine its sensitivity to differentiate between the dissolution profiles of differently formulated and manufactured tablets. Dissolution tests are conducted with both the OPI System and the Standard System using three …

Hydrodynamic Effects Of A Cannula In A Usp Dissolution Testing Apparatus 2, Qianqian Liu

Theses

Dissolution testing is routinely used in the pharmaceutical industry to provide in vitro drug release information for drug development and quality control purposes. The USP Testing Apparatus 2 is the most common dissolution testing system for solid dosage forms. Usually, sampling cannulas are used to take samples manually from the dissolution medium. However, the inserted cannula can alter the normal fluid flow within the vessel and produce different dissolution testing results.

The hydrodynamic effects introduced by a permanently inserted cannula in a USP Dissolution Testing Apparatus 2 were evaluated by two approaches. Firstly, the dissolution tests were conducted with two …

Qsar Modeling Of Chemical Penetration Enhancers Using Novel Replacement Algorithms, Hui Qiu

Theses

The applications of transdermal delivery are limited because of the resistance of the skin to drug diffusion. Only potent drugs, with molecular weight less than 500 Da, are suitable to cross the skin barrier. Chemical Penetration Enhancers (CPEs) are used to promote the absorption of solutes across the dermal layers. In this investigation, a Quantitative Structure-Activity Relationship (QSAR) model is applied to relate chemical penetration enhancer structures with the flux enhancement ratio through a statistical approach.

A database, consisting of 61 non-polar CPEs, is selected for the study. Each compound is represented by 777 QSAR descriptors, which encode the physical …

Session 3-4-A: Public Opinion And Problem Gambling, Don Feeney

International Conference on Gambling & Risk Taking

What do we need to know?

How does the public perceive addiction?

Do they stigmatize addiction?

Do they recognize gambling addiction?

Do they understand the causes?

Do they understand the solutions?

Do they know where to go for help?

Do they know preventative factors?

What are they willing to do?

What messages are credible and appealing?

Session 3-4-C: Are Lottery Players Affected By Random Shocks? Evidence From China’S Individual Lottery Betting Panel Data, Jia Yuan

International Conference on Gambling & Risk Taking

I explore a unique, individual level, lottery betting panel data and show that lottery gambling is significantly affected by lottery winning history even though this winning history is shown to be merely an exogenous random shock. This panel data records lottery players’ collective lottery betting behaviors on a Chinese online lottery purchase website. This website lists each player’s lottery investment performance, the ratio between the lottery return and the lottery investment in the past three months, for lottery players’ reference and this ratio is shown to be an independent random shock across players. Based on the data with around 400,000 …

Session 3-3-D: Interactive Gambling In Australia, Sally Gainsbury, Nerilee Hing, Alex Russell, Alex Blaszczynski, Dan Lubman, Robert Wood

International Conference on Gambling & Risk Taking

Describes interactive gambling and gives its advantages and disadvantages.

Session 3-3-A: An Improved Pathways Development Model Of Problem Gambling: A Summary Of 11 Studies In Hong Kong And Macau, Amy Chiu Sau Lam, Alice Chan Ying Ying, Chi Chuen Chan

International Conference on Gambling & Risk Taking

Introduction

The rationale of this study came from a casual meeting of our supervisor Dr. Chan Chi Chuen and Professor Blaszczynski on a bus after the 2009 Reno conference.

On the bus, C. C. promised Mr. Blaszczynski that he would validate the pathways model in Hong Kong and Macau. And in the next 5 years, Dr. C.C. Chan and his students conducted 11 research projects on problem gambling in Hong Kong and Macau.

Purposes of current study

• To arrive on a summary finding from 11 studies on problem gambling
• To validate the pathways development model proposed by Blaszczynski & Nower …

Session 3-3-C: The National Longitudinal Study Of Gambling Behaviour (Nlsgb): Preliminary Results, Andrew Dellis, Andre Hofmeyr, Harold Kincaid, Don Ross

International Conference on Gambling & Risk Taking

Introduction

The NLSGB tracked 300 gamblers over a 15-month period.

A comprehensive survey instrument was compiled to analyse factors that might influence changes in risk of gambling problems over time.

The study was conducted in the four major metropolitan areas of South Africa: Johannesburg, Tshwane, Durban and Cape Town. We will discuss the study’s design and implementation and some preliminary results.

Session 3-3-B: Recent Eu Gambling Regulatory Developments: A Case Of Many Court Cases With Institutions Courting Inconclusiveness?, Alan Littler

International Conference on Gambling & Risk Taking

Introduction

United Kingdom; shifting towards point of consumption regulation

Member States; competence to regulate is not boundless

Other European institutions; a different discourse?

Session 3-3-A: The ‘Circles Concept’ Of Gambling Addiction: An Empowered Framework For Change, Harry B. Mayr

International Conference on Gambling & Risk Taking

The original ‘Circles Concept of (Gambling) Addiction’ was developed by Harry Mayr in 1982, while working as an addictions counsellor in a community-based health centre. It has always been a ‘user friendly’ concept … applicable and understood by people from all cultures, across all ages, and with or without an addiction issue. Years later, people have informed Mr Mayr how they still remember ‘those circles’, and how the concept helped them.

The ‘Circles Concept of (Gambling) Addiction’ is therefore a concept remembered as much for its visual cues as its verbal explanation – and thus applicable across languages, cognitive and …

Session 3-2-D: Managing A Research Collaborative: Challenges And Outcomes, Joachim Haeusler

International Conference on Gambling & Risk Taking

Collaborative with the Division on Addiction

The collaborative set off in 2005 and since then produced 18 peer reviewed publications, leading to a paradigm shift in online gambling research and which allowed us to establish an evidence-based consumer protection concept.

Goals:

• Creating a scientific evidence base about actual online gambling behavior, relying on behavioral data
• Continuously evaluating games and player protection measures and designing a consumer protection concept based on this evidence
• Creating an early-detection model for the identification of customers at-risk of developing problems

Transparency:

• Full access to de-identified gambling transaction data of large samples (up to 100,000 customers), …

Session 3-2-A: The Conceptual Framework Of Harmful Gambling, Max Abbott

International Conference on Gambling & Risk Taking

Project Overview

Purpose: develop a clear, comprehensive, internationally relevant conceptual framework of harmful gambling that addresses a broad set of factors related to population risk and resilience beyond the symptoms-based view that affects individuals

Previous models inform the work

As the project sponsor, OPGRC is collaborating with an expert panel to facilitate the development of a conceptual framework of harmful gambling that captures the broad set of factors related to harmful gambling

The framework is outlined in a publication, jointly authored by the expert panel members, and presented at the OPGRC website

Session 3-2-D: Predicting Gambling-Related Problems Among Internet Gamblers, Sarah E. Nelson

International Conference on Gambling & Risk Taking

The Goal

Use actual gambling behavior to identify, with good reliability and validity, distinct groups of gamblers among those who have gambling-related problems

Utilize this/these algorithm(s) to set up an early warning system for players at risk of developing problems

Session 3-2-C: Mentor - The New Online Prevention Tool In Use And Its Preliminary Results, Doris Malischnig

International Conference on Gambling & Risk Taking

• Responsible Gaming (RG) Standards Casinos Austria / Austrian Lotteries
• MENTOR: Behavioral Feedback System
• Outlook