Medicine and Health Sciences Commons^™

What's Happening: December 2, 2013, Maine Medical Center

What's Happening

No abstract provided.

Bismuth Nanoparticles As Medical X-Ray Contrast Agents: Synthesis, Characterization And Applications, Anna Laura Brown

Dissertations and Theses

Bismuth based nanomaterials have recently attracted attention as heavy element X-ray contrast agents because of the high atomic number and predicted biological compatibility of bismuth. Nanoparticle X-ray contrast agents may enable a number of novel medical imaging applications, including blood pool and site-directed imaging. However these hypothetical applications are hindered by lack of suitable synthetic methods for production of imaging agents. This dissertation describes synthesis of a novel class of bismuth nanoparticles that are aqueously stabilized using poly and monosaccharides. These particles are synthesized using highly biologically compatible reagents and are oxidatively stable in water and in moderately basic buffered …

Batterer Intervention Programs' Response To State Standards, Ashley Lynn Boal

Dissertations and Theses

The study of policy implementation has recently garnered research and federal attention highlighting the importance of implementation in achieving desired policy and program outcomes (Durlak & DuPre, 2008; Meyers, Durlak & Wandersman, 2012; National Institutes of Health, 2013). Psychology is one discipline that is well poised to guide the study of policy implementation as it can inform the creation, development, and outcomes associated with the introduction of a policy (Esses & Dovidio, 2011; Fischhoff, 1990). Given that batterer intervention programs (BIPs) have been developed to prevent future intimate partner violence (IPV) and improve victim safety, ensuring these programs have successfully …

Development And Application Of A Biorobotic Simulation Of Stance Phase Gait To Study Foot And Ankle Kinematics, Kelly N. Salb

Theses and Dissertations (ETD)

Ankle instantaneous axis of rotation (IAR) measurements represent a more complete parameter for characterizing joint motion. However, few studies have implemented this measurement to study normal, injured, or pathological foot-ankle biomechanics. Additionally, while load is suggested to play a major role in ankle biomechanics, including influences on articular surfaces, bony motion, and formation of the arches, studies concerning the effects of joint loading are limited.

A novel testing protocol was developed to simulate in vivo mechanics of the foot-ankle complex during early stance phase gait in a human cadaveric model. Two studies were conducted. The first study was to assess …

Caring Minds, University Of Texas Health Science Center At Houston School Of Nursing

Caring Minds

• Greetings from Dean Patricia Stark
• Nursing faculty members receive endowment medals at dinner
• “AccPhD” program proves model for faculty growth
• Gifts topping $1.3 million support studies of future nursing educators
• Rozmus selected for 2013 Regents’ Outstanding Teaching Award
• New Practice Doctorate Advances Training for Nurse Anesthetists
• Partners 2013 Spring Luncheon: Cody Unser shares outlook with Partners
• Graduating students select 2013 McGovern Outstanding Teachers
• Diabetes researcher Wang named a 2013 Robert Wood Johnson Foundation ‘Nurse Faculty Scholar’
• School celebrates 40th Anniversary
• UTHealth School of Nursing By the Numbers
• Armstrong inducted as 2013 FAAN, receives $2.4 million NINR grant
• TURN study aims …

Expression Of Phosphodiesterase 6 (Pde6) In Human Breast Cancer Cells, Hongli Dong, Kevin P. Claffey, Stefan Brocke, Paul M. Epstein

UCHC Articles - Research

Considerable epidemiological evidence demonstrates a positive association between artificial light at night (LAN) levels and incidence rates of breast cancer, suggesting that exposure to LAN is a risk factor for breast cancer. There is a 30-50% higher risk of breast cancer in the highest LAN exposed countries compared to the lowest LAN countries, and studies showing higher incidence of breast cancer among shift workers exposed to more LAN have led the International Agency for Research on Cancer to classify shift work as a probable human carcinogen. Nevertheless, the means by which light can affect breast cancer is still unknown. In …

Multiple Hypotheses Testing Procedures In Clinical Trials And Genomic Studies, Qing Pan

Epidemiology Faculty Publications

We review and compare multiple hypothesis testing procedures used in clinical trials and those in genomic studies. Clinical trials often employ global tests, which draw an overall conclusion for all the hypotheses, such as SUM test, Two-Step test, Approximate Likelihood Ratio test (ALRT), Intersection-Union Test (IUT), and MAX test. The SUM and Two-Step tests are most powerful under homogeneous treatment effects, while the ALRT and MAX test are robust in cases with non-homogeneous treatment effects. Furthermore, the ALRT is robust to unequal sample sizes in testing different hypotheses. In genomic studies, stepwise procedures are used to draw marker-specific conclusions and …

Religious Multicultural Competence Amongst Dance/Movement Therapists, Jaclyn Abramson

Creative Arts Therapies Theses

The purpose of this study was to understand how dance/movement therapists, with BC-DMT or R-DMT credentials, acquire, foster, and perceive their own religious multicultural competence. The research question was how do dance/movement therapists develop religious multicultural competence? Through the methodology of a qualitative case study and the data collection method of a focus group, I examined the selfperception of each participant’s own religious multicultural competence. After I transcribed and analyzed the data, I uncovered several themes, highlighted in the Results section. Once the analysis was complete, I utilized the data analysis method of intuitive inquiry. Findings included a) a definition …

An Annotated Bibliography Of Dance/Movement Therapy Appraoches To Eating Disorders, Apryl Marie Grasty

Creative Arts Therapies Theses

This thesis is an annotated bibliography of dance/movement therapy approaches to eating disorders. The leading question of this research was: What information exists on dance/movement therapy approaches to eating disorders? Through data collection of articles, book chapters, online interviews, and the suggestions of therapists in the field, a total of twenty-six sources were annotated in this bibliography. The bibliography is organized by the author’s last name and each citation provides the author’s qualifications, analysis of content, and assessment of strengths and weaknesses. During the research process, the writer discovered that the selection of sources, such as master’s theses, were not …

Enhancing And Sustaining The Personal Wellness/Self-Efficacy Cycle Of A Dance/Movemet Therapy Intern, Lynn R. Chapman

Creative Arts Therapies Theses

The purpose of this study was to investigate the personal wellness/self-efficacy cycle of a dance/movement therapy (DMT) intern, in order to deepen understanding of the interrelatedness of personal wellness and professional self-efficacy, as well as explore how to enhance and sustain them. Interns must develop the skill of self-care in order to promote health, wellness, and confidence in their work and prevent burnout and low self-efficacy. By focusing on process, this study highlighted the skill development of self-care. Therefore, two questions guided this heuristic study: What DMT techniques enhance and sustain my personal wellness/self-efficacy cycle? What is the process that …

Unfolding Self-Esteem Adolescent Girls' Self-Esteem And The Dance/Movement Therapy Intervention Of Improvisation And Planned Movement Formation: A Pilot Study, Mallory Ingram

Creative Arts Therapies Theses

The purpose of this mixed methods single-subject case study pilot was to examine the impact that the dance/movement therapy intervention of improvisation and planned movement formation, created by dance/movement therapy pioneer Trudi Schoop, (Levy, 2005) can have on self-esteem. The research question was: How is adolescent girls’ self-esteem affected by the dance/movement therapy intervention of improvisation and planned movement formation? The hypothesis stated: If the dance/movement therapy intervention of improvisation and planned movement formation is utilized in dance/movement therapy sessions, then adolescent girls’ selfesteem will increase. The study occurred at a private high school with four participants for six sessions. …

The Lived Experience Of Vicarious Trauma For Providers: A Narrative Phenomenoleogical Study, Ambryn D. Melius

Creative Arts Therapies Theses

This research seeks to gain a greater understanding of the first-hand, lived experience of vicarious trauma for providers who have worked with individuals experiencing trauma. Through the application of phenomenological and participatory action methodologies, the experience of vicarious trauma is illuminated. Narrative exchanges between the co-researchers–the author and eleven providers–further explore the roles of the body and narrative process within this phenomenon. A conceptual evolution of vicarious trauma is presented, along with literature connecting the body and narrative within the trauma field. Data includes co-researcher’s recorded and transcribed interviews, vicarious trauma narratives, and written feedback. Embodied writing selections conducted by …

Counselor Identity Development: A Heuristic Look Into The Past, Present, And Future Role Identities, Jaquel Stokes

Creative Arts Therapies Theses

The purpose of this research was to explore and gain further insight into personal and professional roles. Through personal self-reflection, this researcher sought to better understand how her religious/spiritual and teacher roles influenced her professional identity as an emerging dance/movement therapist and counselor. This research study utilized and completed two full cycles of the heuristic methodology by engaging in two stages of data collection and data analyses, and therefore produced two creative syntheses through expressive movement. Nine co-researchers assisted during the investigation of personal and professional role identities. After analyzing and synthesizing the data as a whole, a movement piece …

A Journey Through The Embodiment Of Aggression, Anson Relick

Creative Arts Therapies Theses

The purpose of this research study was to understand what I could learn from my body as I experienced movements based on the observation of children’s aggression. There were several research questions that guided this study: how could the embodiment of aggression prepare me in my journey of becoming a dance/movement therapist? What would develop for me on a body level when I embodied movement qualities I associated with aggression? How could I gain a greater sense of empathy for my patients who act out aggressively? And are there recuperative or preventative measures I could help my patients take, based …

The Phenomenon Of Play Within A Dance/Movement Therapy Setting With Adults, Alison Teichart

Creative Arts Therapies Theses

The purpose of this research was to explore the phenomenon of play and its integration into a dance/movement therapy (DMT) setting with adults. This research focused specifically on adults because play is often neglected during adulthood—despite the fact that play continues to be vital throughout life and has many therapeutic properties. In this phenomenological qualitative study, data was collected through interviews with dance/movement therapists, who identified themselves as using play within their clinical work. From the data, themes were identified, which revealed how dance/movement therapists integrated play into their work and what they experienced as a result of this integration. …

A Profile Of Community Health Center Patients: Implications For Policy, Peter Shin, Carmen Alvarez, Jessica Sharac, Sara J. Rosenbaum, Amanda Van Vleet, Julia Paradise, Rachel Garfield

Geiger Gibson/RCHN Community Health Foundation Research Collaborative

Community health centers are a key source of comprehensive primary care in medically underserved communities across the country, and their role is expected to grow as health coverage expands under the Affordable Care Act (ACA). To sharpen understanding of the health center patient population, this brief compares it to the overall low-income population, using data from the Health Center Patient Survey and the National Health Interview Survey,respectively. The pre-ACA profile of health center patients that emerges sets the stage for measuring change following implementation of the reform law and can inform health center policy, planning, and assessment moving forward.

Hospital Ships Adrift? Part 2: The Role Of U.S. Navy Hospital Ship Humanitarian Assistance Missions In Building Partnerships, Derek J. Licina, Sangeeta Mookherji, Gene Migliaccio, Cheryl Ringer

Global Health Faculty Publications

Introduction US Navy hospital ships are used as a foreign policy instrument to achieve various objectives that include building partnerships. Despite substantial resource investment by the Department of Defense (DoD) in these missions, their impact is unclear. The purpose of this study was to understand how and why hospital ship missions influence partnerships among the different participants.

Methods An embedded case study was used and included the hospital ship Mercy's mission to Timor-Leste in 2008 and 2010 with four units of analysis: the US government, partner nation, host nation, and nongovernmental organizations. Key stakeholders representing each unit were interviewed using …

Comparison Of How Ambient PmC And Pm2.5 Influence The Inflammatory Potential, Matthew Ferguson, Christopher T. Migliaccio, Tony Ward

Public and Community Health Sciences Faculty Publications

Airborne particulate matter (PM) is one of six criteria air pollutants currently regulated by the U.S. Environmental Protection Agency (EPA), with existing ambient standards for PM_2.5 and PM₁₀. Currently there are no health-based regulations for the size fraction between 2.5 and 10 μm, commonly known as the coarse fraction (PM_c). The present study investigates current gaps in knowledge for PM_c including exposure toxicity and PM ratios (PM_c:PM_2.5) in PM₁₀. Throughout the world, all three PM size fractions have been shown to be associated with adverse impacts. Recent studies …

Layered Long Term Co-Culture Of Hepatocytes And Endothelial Cells On A Transwell Membrane: Toward Engineering The Liver Sinusoid, Young Bok (Abraham) Kang, Siddhartha Rawat, Joseph Cirillo, Michael Bouchard, Hongseok (Moses) Noh

Faculty Publications - Biomedical, Mechanical, and Civil Engineering

This paper presents a novel liver model that mimics the liver sinusoid where most liver activities occur. A key aspect of our current liver model is a layered co-culture of primary rat hepatocytes (PRHs) and primary rat liver sinusoidal endothelial cells (LSECs) or bovine aortic endothelial cells (BAECs) on a transwell membrane. When a layered co-culture was attempted with a thin matrigel layer placed between hepatocytes and endothelial cells to mimic the Space of Disse, the cells did not form completely separated monolayers. However, when hepatocytes and endothelial cells were cultured on the opposite sides of a transwell membrane, PRHs …

Chhs December 2013 E-Newsletter, Dr. John Bonaguro, Dean, Vashon S. Wells, Editor, Wku College Of Health & Human Services

College of Health & Human Services Publications

No abstract provided.

Clinical Feasibility Of Noninvasive Visualization Of Lymphatic Flow With Principles Of Spin Labeling Mr Imaging: Implications For Lymphedema Assessment, Swati Rane, Paula M C Donahue, Ted Towse, Sheila Ridner, Michael Chappell, John Jordi, John Gore, Manus J. Donahue

Peer Reviewed Articles

Purpose

To extend a commonly used noninvasive arterial spin labeling magnetic resonance (MR) imaging method for measuring blood flow to evaluate lymphatic flow.

Materials and Methods

All volunteers (n = 12) provided informed consent in accordance with institutional review board and HIPAA regulations. Quantitative relaxation time (T1 and T2) measurements were made in extracted human lymphatic fluid at 3.0 T. Guided by these parameters, an arterial spin labeling MR imaging approach was adapted to measure lymphatic flow (flow-alternating inversion-recovery lymphatic water labeling, 3 × 3 × 5 mm) in healthy subjects (n = 6; mean age, 30 years …

Obesity And Physical Function In Rural Women Who Enroll In A Lifestyle Modification Intervention For Reducing Blood Pressure, Patricia A. Hageman, Carol H. Pullen, Paul J. Dizona, Kristin Schmidt, Linda S. Boeckner

Journal Articles: Physical Therapy

Purpose: Rural women have high prevalence of obesity and prehypertension. Obesity, if associated with poor physical function, may have implications for applying activity guidelines for women volunteering for lifestyle modification. This study examined associations of body mass index (BMI) and percent body fat with measures of 1-mile walk time, post-walk perceived exertion, and 10-repetition chair stands in rural women ages 40-69.

Methods: Cross-sectional baseline data were collected using standardized methods from 289 rural women with prehypertension who volunteered for a lifestyle clinical trial for reducing blood pressure. ANOVAs and linear regression were used for analysis.

Results: With exception of the …

Agpt Registrar Satisfaction Survey 2013, Rebecca Taylor, Hamish B. Coates

Higher education research

The General Practice Education and Training Limited (GPET) Registrar Satisfaction Survey (RSS) is used for ensuring continuous improvement in the training of doctors in General Practice. Designed by the Australian Council of Educational Research (ACER) in conjunction with GPET and advisors from the Association of Chief Executives (ACE), the RSS gauges the level of registrar satisfaction with the quality of their training, with training providers, and with career progression. It was designed and implemented to help ensure that professional training programs delivered by Regional Training Providers (RTPs) meet the standards and requirements of both the Royal Australian College of General …

Molecular Epidemiology Of Escherichia Coli Sequence Type 131 And Its H30 And H30-Rx Subclones Among Extended-Spectrum-Β-Lactamase-Positive And -Negative E. Coli Clinical Isolates From The Chicago Region, 2007 To 2010, Ritu Banerjee, Ari Robicsek, Michael A. Kusikowski, Stephen Porter, Brian D. Johnston, Evgeni Sokurenko, Veronika Tchesnokova, Lance B. Price, James R. Johnson

Environmental and Occupational Health Faculty Publications

We assessed Escherichia coli ST131 and its H30 and H30-Rx subclones for virulence genes, antimicrobial resistance, and extended-spectrum beta-lactamase (ESBL) type. Although both subclones were associated with ESBL production, H30-Rx isolates had higher resistance scores and were associated specifically with CTX-M-15. Three virulence genes (iha, sat, and iutA) were more prevalent among H30 than non-H30 ST131 isolates. Thus, the H30 and H30-Rx subclones are more antimicrobial resistant and have virulence profiles that are distinct from those of non-H30 ST131 isolates.

Anticancer Properties Of Distinct Antimalarial Drug Classes, Rob Hooft Van Huijsduijnen, R. Kiplin Guy, Kelly Chibale, Richard K. Haynes, Ingmar Peitz, Gerhard Kelter, Margaret A. Phillips, Jonathan L. Vennerstrom, Yongyuth Yuthavong, Timothy N. C. Wells

Journal Articles: Pharmaceutical Sciences

We have tested five distinct classes of established and experimental antimalarial drugs for their anticancer potential, using a panel of 91 human cancer lines. Three classes of drugs: artemisinins, synthetic peroxides and DHFR (dihydrofolate reductase) inhibitors effected potent inhibition of proliferation with IC50s in the nM- low µM range, whereas a DHODH (dihydroorotate dehydrogenase) and a putative kinase inhibitor displayed no activity. Furthermore, significant synergies were identified with erlotinib, imatinib, cisplatin, dasatinib and vincristine. Cluster analysis of the antimalarials based on their differential inhibition of the various cancer lines clearly segregated the synthetic peroxides OZ277 and OZ439 from the artemisinin …

Emotional Intelligence And Community Healthcare Productivity, Christopher Jacob Fox

Dissertations

Economic crisis is threatening state budgets. The strain on state budgets effects pensions and the healthcare benefits to communities. Rising healthcare costs and lagging insurance reimbursement rates are forcing healthcare organizations to sustain programs with fewer financial resources. Research studies indicate that payment increases from Medicare and Medicaid will not keep pace with the historical trend in hospital cost inflation (Kaufman, 2011). Of the healthcare facilities affected by federal budget constraints are community mental healthcare centers. The strain on state budgets has taken its toll on community mental healthcare facilities in particular struggling under the healthcare reform initiatives (Simpson, 1995). …

Reproducibility Of Ambulatory Blood Pressure Changes From The Initial Values On Two Different Days, Garrett I. Ash

Open Access Author Fund Awardees' Articles

OBJECTIVE: We tested the reproducibility of changes in the ambulatory blood pressure (BP) from the initial values, an indicator of BP reactivity and cardiovascular health outcomes, in young, healthy adults. METHOD: The subjects wore an ambulatory BP monitor attached by the same investigator at the same time of day until the next morning on two different days (day 1 and day 2) separated by a week. We compared the ambulatory BP change from the initial values at hourly intervals over 24 waking and sleeping hours on days 1 and 2 using linear regression and repeated measures analysis of covariance. RESULTS: …

Challenges Of Asthma Management For School Nurses In Districts With High Asthma Hospitalization Rates, Penny Liberatos, Jennifer Leone, Ann Marie Craig, Elizabeth Mary Frei, Natalie Fuentes, India Marie Harris

NYMC Faculty Publications

BACKGROUND: School nurses play a central role in assisting elementary school children in managing their asthma, especially those in higher-risk school districts that are at increased risk of uncontrolled asthma. Study purposes are to (1) identify barriers to asthma management by school nurses in higher-risk school districts; and (2) assess the extent to which National Asthma Education and Prevention Program (NAEPP) recommendations are followed in these districts. METHODS: School districts containing at least one zipcode with high asthma hospitalization rates among children (0-14 years) in a New York State county were identified. Nurses in 44 elementary schools were surveyed about …

Gonadal Status-Dependent Effects Of In Vivo Β-Estradiol Administration To Female Rats On In Vitro Epileptiform Activity Induced By Low [Mg2+]₀ In Combined Hippocampus-Entorhinal Cortex Slices, Jana Velíšková, Libor Velíšek

NYMC Faculty Publications

There are controversial data regarding estrogen effects on neuronal excitability. We investigated whether β-estradiol (EB) administration to ovariectomized (OVX) or gonadally intact female rats alters epileptiform activity within the dentate gyrus network induced in vitro by removing [Mg2+]o in combined hippocampus-entorhinal cortex slices. In vivo EB administration significantly influenced the epileptiform activity in gonadal status-dependent manner. The onset of epileptiform discharges was modestly delayed in slices from OVX rats replaced with physiologically relevant doses of EB but the number of discharges was not affected. In contrast, EB administration to gonadally intact rats had robust effects such that: EB delayed the …

Structure Matters: Examining Illness Behavior Using Parsons's Sick Role, Angela D. Byrd

Masters Theses & Specialist Projects

Although Talcott Parsons’s sick role theory, as described in 1951 in The Social System, has been severely criticized for its inapplicability to chronic illnesses, a portion of the theory is still a relevant and necessary factor in terms of understanding and treating chronic illness today. Using data from the 2012 National Health Interview Survey, this study looks at the individual effects of sex, age, race, cohabitation, education and region of residence on the likelihood of chronically ill patients considering themselves limited in their amount or kind of work as an indicator of sick role adaptation. Results show statistically significant relationships …