Medicine and Health Sciences Commons^™

Lot Quality Assurance Sampling (Lqas) And The Mozambique Malaria Indicator Surveys, Caitlin Biedron, Marcello Pagano, Bethany L. Hedt, Albert Kilian, Amy Ratcliffe, Samuel Mabunda, Joseph J. Valadez

Harvard University Biostatistics Working Paper Series

No abstract provided.

Talk To Me: Issues In Acquiring Spoken Language For Young Children With Autism Spectrum Disorders, Rhea Paul

Communication Disorders Faculty Publications

Speech-language pathologists play a critical role in the treatment of children with autism spectrum disorders (ASD) because communication deficits are a primary component of both the diagnostic criteria and the focus of educational services for children with these conditions. Children with ASD almost always are delayed in speech acquisition (Tager-Flusberg, Paul, & Lord, 2005), as well as in other areas of communication. Lack of speech is often the most obvious symptom and greatest cause for concern of parents of toddlers who are eventually diagnosed with ASD, even though closer observation usually reveals additional problems.

Ada News - 11/02/2009, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Victims Of Violence Among Indigenous Mothers Living With Dependent Children, Kyllie Cripps, Catherine M. Bennett, Lyle C. Gurrin, David M. Studdert

Aboriginal Policy Research Consortium International (APRCi)

Objective: Toidentifyindividualandhouseholdfactorsassociatedwithviolenceamong Australian Indigenous women with dependent children. Design and participants: Univariate and multivariable analysis of data from the 2002 National Aboriginal and Torres Strait Islander Social Survey, stratified by area.

Main outcome measure: Self-reported experience of being a victim of violence in the previous year. Results: OneinfourIndigenouswomenlivingwithdependentchildrenyoungerthan 15 years reported being victims of violence in the previous year; this corresponds to an estimated 24 221 Indigenous mothers (95% CI, 21 507–26 935) nationwide. Violence was more prevalent in regional areas and cities than remote areas. In remote areas, mothers who had been removed from their natural families during childhood …

No Powerpoint? Whatever Loys Your Krathong ..., Kimberly D. Acquaviva

National Collaborative on Aging Faculty Publications

The author discusses her experiences teaching a workshop on writing for publication to medicine, nursing and public health faculty in Thailand, without using PowerPoint.

Small-Molecule Screening Using A Human Primary Cell Model Of Hiv Latency Identifies Compounds That Reverse Latency Without Cellular Activation, Hung Chih Yang, Sifei Xing, Liang Shan, Karen O'Connell

University Faculty Publications and Creative Works

The development of highly active antiretroviral therapy (HAART) to treat individuals infected with HIV-1 has dramatically improved patient outcomes, but HAART still fails to cure the infection. The latent viral reservoir in resting CD4+ T cells is a major barrier to virus eradication. Elimination of this reservoir requires reactivation of the latent virus. However, strategies for reactivating HIV-1 through nonspecific T cell activation have clinically unacceptable toxicities. We describe here the development of what we believe to be a novel in vitro model of HIV-1 latency that we used to search for compounds that can reverse latency. Human primary CD4+ …

Alcohol Use And Gender Effects On Hiv Risk Behaviors In Cocaine-Using Methadone Patients, Carla J. Rash, Nancy M. Petry

UCHC Articles - Research

Injection drug users engage in behaviors that increase the spread of human immunodeficiency virus (HIV) and other infectious diseases. Although methadone maintenance (MM) is highly effective in decreasing heroin use and the spread of HIV, polydrug use, especially the combined use of cocaine and alcohol, is common in MM patients. Alcohol use is independently associated with HIV risk behaviors, and the effects of alcohol use on risk behaviors may vary by gender. This study evaluated the effects of recent heavy alcohol use and gender with respect to HIV risk behaviors in 118 cocaine-abusing methadone patients. Both lifetime and past month …

Individualized Assessment And Treatment Program For Alcohol Dependence: Results Of An Initial Study To Train Coping Skills, Mark D. Litt, Ronald M. Kadden, Elise Kabela-Cormier

UCHC Articles - Research

Cognitive-behavioral treatments (CBT) are among the most popular interventions offered for alcohol and other substance use disorders, but it is not clear how they achieve their effects. CBT is purported to exert its beneficial effects by altering coping skills, but data supporting coping changes as the mechanism of action are mixed. The purpose of this pilot study was to test a treatment in which coping skills were trained in a highly individualized way, allowing us to determine if such training would result in an effective treatment. Conclusions The IATP approach was more successful than PCBT at training adaptive coping responses …

Rna-Guided Rna Cleavage By A Crispr Rna-Cas Protein Complex, Brenton R. Graveley, Sara Olson, Michael O. Duff

UCHC Articles - Research

Compelling evidence indicates that the CRISPR-Cas system protects prokaryotes from viruses and other potential genome invaders. This adaptive prokaryotic immune system arises from the clustered regularly interspaced short palindromic repeats (CRISPRs) found in prokaryotic genomes, which harbor short invader-derived sequences, and the CRISPR-associated (Cas) protein-coding genes. Here we have identified a CRISPR-Cas effector complex that is comprised of small invader-targeting RNAs from the CRISPR loci (termed prokaryotic silencing (psi)RNAs) and the RAMP module (or Cmr) Cas proteins. The psiRNA-Cmr protein complexes cleave complementary target RNAs at a fixed distance from the 3' end of the integral psiRNAs. In Pyrococcus furiosus …

Control Of Electrochemical And Ferryloxy Formation Kinetics Of Cyt P450s In Polyion Films By Heme Iron Spin State And Secondary Structure, Sadagopan Krishnan, Amila Abeykoon, John B. Schenkman, James F. Rusling

UCHC Articles - Research

Voltammetry of cytochrome P450 (cyt P450) enzymes in ultrathin films with polyions was related for the first time to electronic and secondary structure. Heterogeneous electron transfer (hET) rate constants for reduction of the cyt P450s depended on heme iron spin state, with low spin cyt P450cam giving a value 40-fold larger than high spin human cyt P450 1A2, with mixed spin human P450 cyt 2E1 at an intermediate value. Asymmetric reduction–oxidation peak separations with increasing scan rates were explained by simulations featuring faster oxidation than reduction. Results are consistent with a square scheme in which oxidized and reduced forms of …

State Medicaid Coverage Of Perinatal Services: Summary Of State Survey Findings, Usha Ranji, Alina Salganicoff, Alexandra M. Stewart, Marisa A Cox, Lauren Doamekpor

Health Policy and Management Faculty Publications

No abstract provided.

Medical Education Digest, Vol. 11 No. 6 (November/December 2009), Nova Southeastern University

Medical Education Digest

No abstract provided.

Medical School Watercooler Newsletter - November 1, 2009, Lindsey Lyle

Watercooler Newsletter

This is the November 1, 2009 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler

Contents Include

• USA Physicians Group Cardiology Participates in Employee Benefits Fair

• USA Biomedical Library Honored with 2009 Distinguished Library Award

• Faculty Appreciation Tent at this Saturday's Homecoming Game

• Former COM Associate Dean Confirmed As Surgeon General

• COM Fall Faculty Assembly

• Abstract Deadline Extended - 3rd Annual USA COM Research Forum

• USA COM Grad & Surgery Resident Remembered

• Redox Regulation of IFG-I and Integrin Signaling in Chondrocytes - This Week's DSS

• Sickle Cell Today - Now Online

Successive Bouts Of Cycling Stimulates Genes Associated With Mitochondrial Biogenesis, Charles Dumke, J. Mark Davis, E. Angela Murphy, David C. Nieman, Martin D. Carmichael, John C. Quindry, N. Travis Triplett, Alan C. Utter, Sarah J. Gross Gowin, Dru Henson, Steven R. Mcanulty, Lisa S. Mcanulty

Integrative Physiology and Athletic Training Faculty Publications

Exercise increases mRNA for genes involved in mitochondrial biogenesis and oxidative enzyme capacity. However, little is known about how these genes respond to consecutive bouts of prolonged exercise. We examined the effects of 3 h of intensive cycling performed on three consecutive days on the mRNA associated with mitochondrial biogenesis in trained human subjects. Forty trained cyclists were tested for VO_2max (54.7 ± 1.1 ml kg⁻¹ min⁻¹). The subjects cycled at 57% watts_max for 3 h using their own bicycles on CompuTrainer™ Pro Model trainers (RacerMate, Seattle, WA) on three consecutive days. Muscle biopsies were …

Helping Immigrant And Refugee Students Succeed: It's Not Just What Happens In The Classroom, Eileen Kugler, Olga Acosta Price

Center for Health and Health Care in Schools

No abstract provided.

Microbiological, Clinical, And Surgical Features Of Fungal Prosthetic Joint Infections: A Multi-Institutional Experience, Khalid Azzam, Javad Parvizi, Donald Jungkind, Arlen Hanssen, Thomas Fehring, Bryan Springer, Kevin Bozic, Craig Della Valle, Luis Pulido, Robert Barrack

Open Access Publications

No abstract provided.

A Phenomenological Study Of Clinicians Treating Traumagenic Compulsions Resulting From Childhood Sexual Abuse, Albert Sarno

Faculty Dissertations

Various types of traumatic compulsive behaviors have been observed by practicing mental health clinicians and yet there is a lack of consensus among such clinicians for treating people in such a problematic state when there is also a history of childhood sexual abuse. Ten seasoned clinicians, each with over 15 years experience in treating patients with traumagenic compulsions and childhood sexual abuse were interviewed to explore their lived experience treating people with traumagenic compulsions due to childhood sexual abuse. A phenomenological design was used to asses the data collected in the study. The data were analyzed to determine the best …

Computer-Based Cognitive Interventions For Persons With Dementia: Feasibility And Outcomes, Nidhi Mahendra, Allegra Apple, Susan Carroll, Adithya Chandregowda

Faculty Publications

No abstract provided.

Barriers Influencing Minority Clients’ Access To Speech Language Pathology Services. Poster, Nidhi Mahendra, Katie Schoneman, Nisha Engineer

Faculty Publications

No abstract provided.

Sox11 Expression Is Highly Specific For Mantle Cell Lymphoma And Identifies The Cyclin D1-Negative Subtype., Ana Mozos, Cristina Royo, Elena Hartmann, Daphne De Jong, Cristina Baró, Alexandra Valera, Kai Fu, Dennis D. Weisenburger, Jan Delabie, Shih-Sung Chuang, Elaine S. Jaffe, Carmen Ruiz-Marcellan, Sandeep Dave, Lisa Rimsza, Rita Braziel, Randy D. Gascoyne, Francisco Solé, Armando López-Guillermo, Dolors Colomer, Louis M. Staudt, Andreas Rosenwald, German Ott, Pedro Jares, Elias Campo

Journal Articles: Pathology and Microbiology

BACKGROUND: Cyclin D1-negative mantle cell lymphoma is difficult to distinguish from other small B-cell lymphomas. The clinical and pathological characteristics of patients with this form of lymphoma have not been well defined. Overexpression of the transcription factor SOX11 has been observed in conventional mantle cell lymphoma. The aim of this study was to determine whether this gene is expressed in cyclin D1-negative mantle cell lymphoma and whether its detection may be useful to identify these tumors.

DESIGN AND METHODS: The microarray database of 238 mature B-cell neoplasms was re-examined. SOX11 protein expression was investigated immunohistochemically in 12 cases of cyclin …

Selected Comparison Of Global Health Organizations, Steven C. Mccullar

Scholarship in Medicine - All Papers

Due to a potential, worldwide adverse impact on health, transnational dependencies, and the need for effective response, global cooperation is imperative (Buchanan & Decamp, 2006). There are more than 100 global health agencies, including the World Health Organization. As the number of organizations increases, each with their own agendas, so does the concern for lack of coherence and collaboration among organizations in the effort of disease eradication and development of health systems (Beaglehole & Bonita, 2008). The focus of this study is on comparing the effectiveness of selected global health organizations in efforts to detect a need to either establish …

Information Interface - Volume 37, Issue 4 - November/December 2009, George Washington University, Himmelfarb Health Sciences Library

Information Interface (1976 - 2009)

News and information about Himmelfarb Health Sciences Library of interest to users. Includes articles on the PubMed redesign, 2010 Journal Collection, and mobile resources.

A Free And Undemocratic Press?, Stephen J. A. Ward

Center for the Study of Ethics in Society Papers

Papers presented for the Center for the Study of Ethics in Society Western Michigan University.

Patellar Resurfacing Compared With Nonresurfacing In Total Knee Arthroplasty: A Concise Follow-Up Of A Randomized Trial, R. Stephen Burnett, Julienne L. Boone, Seth D. Rosenzweig, Karen Steger-May

Open Access Publications

No abstract provided.

Four Centuries Of Military Surgery In Canada, Vivian Mcalister

Data and Test Instruments

No abstract provided.

Timing Of Moderate Level Prenatal Alcohol Exposure Influences Gene Expression Of Sensory Processing Behavior In Rhesus Monkeys, Mary L. Schneider, Colleen F. Moore, Julie A. Larson, Christina S. Barr, Onofre T. Dejesus, Andrew D. Roberts

Physics and Astronomy Department Publications

Sensory processing disorder, characterized by over- or under-responsivity to non-noxious environmental stimuli, is a common but poorly understood disorder. We examined the role of prenatal alcohol exposure, serotonin transporter gene polymorphic region variation (rh5-HTTLPR), and striatal dopamine (DA) function on behavioral measures of sensory responsivity to repeated non-noxious sensory stimuli in macaque monkeys. Results indicated that early gestation alcohol exposure induced behavioral under-responsivity to environmental stimuli in monkeys carrying the short (s) rh5-HTTLPR allele compared to both early-exposed monkeys homozygous for the long (l) allele and monkeys from middle-to-late exposed pregnancies and controls, regardless of genotype. …

What's Happening: November-December, 2009, Maine Medical Center

What's Happening

No abstract provided.

Mechanism Of Nsf: New Evidence Challenging The Prevailing Theory, Ben B. Newton, Phd, Sergio A. Jimenez, Md

Scleroderma Center Faculty Papers

Nephrogenic systemic fibrosis (NSF) has been associated with the administration of gadolinium-based contrast agents in patients with severely impaired renal function (SIRF), endstage renal disease (ESRD), or acute renal failure (ARF). Since the vast majority of these patients do not get NSF, it is highly likely that patient factors play a role in its development. Although free or dechelated gadolinium is thought by some to be the only trigger of NSF, recent evidence suggests that chelated gadolinium may be important. Chelated gadolinium such as Omniscan (gadodiamide) and Magnevist (gadopentetate) can directly stimulate macrophages and monocytes in vitro to release profibrotic …

Truck Drivers Killed After Exiting Semi Tractors And Being Struck By Other Semi Tractors In Distribution Center, Kentucky Injury Prevention And Research Center

Kentucky Haz Alerts--Motor Vehicle

To prevent truck driver injuries while traversing distribution facilities:

• Drivers of yard tractors should ensure that a clear path is visible before moving the vehicle. Truck drivers should not approach such vehicles on foot until acknowledgment of contact has been made between both drivers.
• Do not enter behind the trailer until other vehicle drivers behind have come to a complete stop and parked the vehicle.
• Always wear reflective vests while traversing a distribution facility.
• Employers should develop and implement a comprehensive safety plan that addresses truck driver pedestrian traffic in freight distribution facilities.
• All air lines and electrical connections should …

Child Labour: A Public Health Issue, Saleema A. Gulzar, Samina Vertejee, Laila Pirani

School of Nursing & Midwifery

Child labour is a global practice and has many negative outcomes. According to International Labour Organization, child labour is the important source of child exploitation and child abuse in the world today. The Human Rights Commission of Pakistan has estimated the number of Pakistani working children to be around 11-12 millions, out of which, at least, half the children are under the age of ten years. It portrays the society's attitude towards child care. It is therefore, essential to break this vicious cycle and hence, enable the society to produce healthy citizens. This article analyzes the determinants of child labour …