Medicine and Health Sciences Commons^™

Antiretroviral Therapy Dose Adjustments Based On Calculated Creatinine Clearance, J. Shavadia, G. Tesfaldet, Majid Twahir

Internal Medicine, East Africa

Background: Whereas therapy for HIV is dependent on level of creatinine clearance, most laboratories locally only report an absolute creatinine value. There is likelihood that the patients already on antiretroviral therapy (ART) may have required dosage adjustment at the time of initiation of therapy or sometime during ongoing therapy. This paper explores a group of patients who are already on ART to determine their creatinine clearance and assess the need for ART dose adjustment.

Objective: To determine the proportion of stable HIV outpatients who have a documented creatinine clearance (CrCI) and the proportion requiring antiretroviral drug dose adjustments depending on …

Lsuhsc Facilities Daily Update: April 2009, Lsuhsc Property And Facilities Management

LSUHSC Facilities Daily Updates: 2009

LSUHSC Dailly Facilities Updates from April 2009.

These updates describe damage and a timeline of repairs at the LSU Health Sciences Center - New Orleans campus due to Hurricane Katrina which made landfall August 29, 2005.

Lsuhsc Facilities Biweekly Update: April 2009, Lsuhsc Property And Facilities Management

LSUHSC Facilities Biweekly Updates: 2009

LSUHSC Facilities Biweekly Updates from April 10 and 24, 2009.

These updates describe damage and a timeline of repairs at the LSU Health Sciences Center - New Orleans campus due to Hurricane Katrina which made landfall August 29, 2005.

La Calidad Del Agua Potable En Arica, Con Respecto A La Salud, Emily Lubell

Independent Study Project (ISP) Collection

Water is essential to sustain life, and the availability of safe drinking water is a concern throughout the world. This study examines the potential negative health effects related to drinking the potable water in Arica, Chile. It also looks at who has access to purified water. This study was implemented over a span of four weeks in which information was collected from different local resources including, the potable water distributor, private water vendors, professors, and public health service workers. In comparison with 2001, 2009 levels of boron, total hardness and total dissolved solids are higher in concentration. In both 2001 …

Health Educator Job Analysis Project: Timeline Report, Eva Doyle, Beverly S. Mahoney

Faculty Publications and Presentations

No abstract provided.

A Case Of Finger Clubbing Associated With Nasopharyngeal Carcinoma In A Young Girl, And Review Of Pathophysiology, Nasir Ali, Ahmed Nadeem Abbasi, Farook Karsan, Raheel Hashmi, Quratul-Ain Badar, Asim Jamal Sheikh

Department of Radiation Oncology

Hypertrophic osteoarthropathy is characterized by clubbing of the digital tips and periosteal reaction of long bones. Most of the cases are associated with malignancy or other conditions such as congenital heart disease, liver cirrhosis, pulmonary fibrosis, biliary atresia and gastrointestinal polyps. Hypertrophic osteoarthropathy associated with malignancy is rare in children. A few cases of hypertrophic osteoarthropathy in children with nasopharyngeal carcinoma have been reported. This is a case of hypertrophic osteoarthropathy associated with nasopharyngeal carcinoma with lung and bone metastasis in a 16 year old girl. In this case, lung metastases progressed after intensive chemotherapy and hypertrophic osteoarthropathy (Clubbing) persisted.

Management Of Allergic Fungal Sinusitis With Postoperative Oral And Nasal Steroids: A Controlled Study., Mubasher Ikram, Akbar Abbas, Anwar Suhail, Maisam Abbas Onali, Shabbir Akhtar, Moghira Iqbal

Section of Otolaryngology, Head & Neck Surgery

In Patients with allergic fungal sinusitis, the mainstay of treatment remains surgical removal of allergic mucin and fungal debris. But as a single modality, surgery is associated with high rates of recurrence, so a number of adjunctive medical modalities have been tried, including postoperative corticosteroid therapy. We conducted a study of 63 Patients with allergic fungal sinusitis who underwent endoscopic sinus surgery with or without postoperative steroid therapy. A group of 30 Patients who had been treated prior to January 2000 had undergone surgery only, their cases were reviewed retrospectively, and they served as historical controls. Another 33 Patients who …

“The Womb People” : Detection, Treatment, And Prevention Of Cervical Cancer With The Khayelitsha Cervical Cancer Screening Project In Khayelitsha, South Africa, Kirsten Lynch

Independent Study Project (ISP) Collection

The current policy concerning cervical cancer screenings is not effectively addressing the specific needs of the female South African population. The program, as outlined by the South African Department of Health, is not sufficiently accessing women due to problems in availability, access, organization, and education. As women are living longer with HIV/AIDS, due to antiretroviral (ARV) treatment, they are becoming more susceptible to opportunistic infections that can lead to cervical cancer, such as Human strains of the virus can be prevented with administration of an HPV vaccination and advancement of precancerous lesions can be detected and treated with current technology. …

Mitigating The Impact Of Aids On A Rural Community: Observations Of The Inner Workings Of A Rural Non-Governmental Organization, Kara Huselton

Independent Study Project (ISP) Collection

The purpose of this study project was to understand the impact of HIV/AIDS on a community and to assess the ability of a non-governmental organization to mitigate the negative effects of disease and poverty in the spaces where the government has failed to address community needs. The author observed employees at the Bhekuzulu Self Sufficient Project in rural KwaZulu Natal over a period of three and a half weeks in order to gain an understanding of the work done there. Secondary research was done to supplement these observations and better understand the social and economic impact of HIV/AIDS on a …

Herbs, Qur’An, And Mashetani: Practice, Use, Perception, And Integration Of Traditional Medicine In Bodo, Elan Ebeling

Independent Study Project (ISP) Collection

This study examines the practice, use and perception of traditional medicine in the rural village of Bodo, on the south coast of Kenya. This paper surveys the different types, treatments, and education of traditional medical practitioners, as well as assesses the accessibility of both traditional and conventional medicine facilities. Secondly, it addresses the perceptions of different community members of illness and healthcare, and, in the light of recent attempts to integrate traditional medicine into the national healthcare system, examines how these perceptions work in conjunction with accessibility to influence the use of healthcare.

Public Health Ethics: Establishing “Durable Solutions” Within The Global Polio Eradication Initiative In Nigeria, Tiffany T. Mason

Independent Study Project (ISP) Collection

Discussions on public health ethics often appeal to the same codes of conduct established in the field of bioethics. Principles of bioethics contribute to the morality of the study of public health—proposing an optimal code of conduct in the medical care and human research aspects of the field. For example, public health researchers are aware of their obligations to consider informed consent, confidentiality, and the equal distribution of risks and benefits in the implementation of their studies and interventions. However, public health practice extends far beyond medical care and human research. Thus, it is inappropriate to assume that codes established …

Tuberculosis Por Los Ojos De La Vida Aymara: La Correlación Entre Estilo De Vida Y Tuberculosis En Los Aymara Del Norte De Chile, Sam Percy

Independent Study Project (ISP) Collection

Background: Explanations for disparities in health between groups of people are complex, and based in differences in genetics, environment, access to medical care, socioeconomic, educational, and cultural factors. In short a person’s lifestyle is inextricably related to a person’s health and their propensity to contract disease. Members of the indigenous group Aymara who live in Arica, Chile have 6 times the rate of morbidity from Tuberculosis (TB) as non-Aymara and 9 times the rate of mortality from the disease. This study examined if there was a link between the rate of TB amongst the Aymaran people and the way Aymarans …

Vih Y Alcohol En Arica, Chile: Percepciones De Portadores Y Profesionales, Lena Sessions

Independent Study Project (ISP) Collection

This paper investigated the relationship between alcohol consumption and HIV in Arica, Chile. The objectives of this investigation were to understand the demographics of HIV positive Ariqueños who consume alcohol, and understand their perceptions of alcohol consumption with respect to whether they believed they had a drinking problem, whether they believed that the consumption of alcohol facilitated their contracting HIV, and whether the consumption of alcohol affected their treatment. Although there is no literature that specifically addresses the topic of how HIV positive individuals who consume alcohol perceive their disease, former research suggests that a significant number (25-50%) of individuals …

Community, Infant Feeding, And Aids: Empowerment Evaluation In Rural Eastern Cape, Laura Flamm

Independent Study Project (ISP) Collection

As a part of a three week learnership practicum, empowerment evaluation principles and practices were applied to antenatal and postnatal infant feeding counseling services offered by Iapile Gateway Clinic’s prevention of mother to child transmission (PMTCT) of HIV program. Empowerment evaluation engages stakeholders through the processes of planning, implementation, and evaluation, ultimately building these stakeholders’ capacities to sustain and improve services. Because of powerful sociocultural norms regarding infant feeding, empowerment evaluation was selected as a tool that would allow for sustainable and hermeneutic evaluation of the program, taking into account its dialectic relationship with local knowledge on infant feeding.

Data …

Mental Health In Mali: An Analysis Of The Expression Of Major Depressive Disorder Across Different Cultures, Ashley Morris

Independent Study Project (ISP) Collection

Introduction (excerpt) What other differences exist between illnesses across different cultures? Are the differences only found in the manifestation of symptoms or are there also biological differences? How does one conceptualize mental health issues, such as depression, here in Mali? Is there a stigma against mental health patients in Mali? What facilities, treatments, and medicines are available in Mali to treat mental disorder? After a little more background research I found that the topic of mental health in the developing world has been largely ignored until very recently. As cross-cultural studies in every academic discipline become increasingly more prevalent, anthropology …

Thoracoscopy In Children: Is A Chest Tube Necessary?, Todd A. Ponsky, Steven S. Rothenberg, Kuojen Tsao, Daniel J. Ostlie, Shawn D. St Peter, G W. Holcomb Iii

Manuscripts, Articles, Book Chapters and Other Papers

PURPOSE: Historically, a chest tube or drain has been left following a thoracic operation to allow drainage of air or fluid in the postoperative period. However, in patients undergoing thoracoscopy, the tube is often the greatest source of postoperative pain. We began excluding chest tubes several years ago and therefore are reviewing our experience to evaluate the safety and efficacy of this approach.

METHODS: A retrospective review of the medical record was performed on patients undergoing thoracoscopy at two centers from 1993 to 2007. Patients who left the operating room without a chest tube were included in this series. Patient …

Universal Screening For Extracardiac Abnormalities In Neonates With Congenital Heart Disease., Javier H. Gonzalez, Girish S. Shirali, Andrew M. Atz, Sarah N. Taylor, Geoffrey A. Forbus, Sinai C. Zyblewski, Anthony M. Hlavacek

Manuscripts, Articles, Book Chapters and Other Papers

Extracardiac or genetic abnormalities (EGA) represent a factor in the morbidity of patients with congenital heart disease. We evaluated the way neonates with CHD are screened at our institution and determined the yield for the screening tests. We reviewed the charts of 223 neonates with structural CHD. Subjects were categorized into 6 groups: univentricular, left-sided obstructive lesions, right-sided obstructive lesions, septal defects, conotruncal defects (CTD), and other. We reviewed which patients underwent cranial ultrasonogram (CUS), abdominal ultrasonogram (AUS), and/or genetic studies (GS) as well as their results. There was a high prevalence of EGA in each group by CUS (32% …

J Am Coll Dent 2009 76 2

Journal of the American College of Dentists

The Journal of the American College of Dentists (JACD) publishes scholarly articles, editorials, essays, and reflections addressing the ethical, professional, and social dimensions of dentistry. The Journal serves as a forum for advancing ethics, professionalism, leadership, and excellence within the dental community. By fostering dialogue across disciplines and perspectives, JACD provides readers with insights that encourage ethical, professional practice, lifelong learning, and service to the public, reinforcing dentistry’s commitment to advancing oral healthcare and the common good.

The Advanced Dental Hygiene Practitioner At The Master's-Degree Level: Is It Necessary?, Michele Leonardi Darby

Dental Hygiene Faculty Publications

The article reflects on the Advanced Dental Hygiene Practitioner (ADHP) curriculum proposed by the American Dental Hygienists' Association at the master's degree level. It is stated that dental hygienists and ADHPs can collaborate with other health care professionals for contributing towards the advancement of quality health care to the most vulnerable populations. It is mentioned that preparation at the master's degree is a logical pathway to the expanded scope of practice.

Factors Associated With Receipt Of Preventive Dental Treatment Procedures Among Adult Patients At A Dental Training School In Wisconsin, 2001-2002, Christopher Okunseri, Ruta Bajorunaite, Jessica Mehta, Brian D. Hodgson, Anthony Iacopino

School of Dentistry Faculty Research and Publications

Background: Gender differences in oral health-related quality of life and the fear of dental pain in seeking and receiving preventive dental care have been recognized and documented. Preventive dental treatment procedures (PDTPs) are commonly accepted as the primary approach to prevent dental disease.
Objective: We examined whether the likelihood of receiving PDTPs differed by gender in adult patients receiving dental care at a dental training institution in Milwaukee, Wisconsin.
Methods: Data from the Marquette University School of Dentistry electronic patient management database for 2001 through 2002 were analyzed. Descriptive, bivariate, and multivariable analyses were performed. The preventive procedures used in …

Comorbidities, Patient Knowledge, And Disease Management In A National Sample Of Patients With Copd, R Graham Barr, Bartolome R Celli, David M Mannino, Thomas Petty, Stephen I Rennard, Frank C Sciurba, James K Stoller, Byron M Thomashow, Gerard M Turino

Faculty, Staff and Student Publications

OBJECTIVE: Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death in the United States but is often undertreated. COPD often overlaps with other conditions such as hypertension and osteoporosis, which are less morbid but may be treated more aggressively. We evaluated the prevalence of these comorbid conditions and compared testing, patient knowledge, and management in a national sample of patients with COPD.

METHODS: A survey was administered by telephone in 2006 to 1003 patients with COPD to evaluate the prevalence of comorbid conditions, diagnostic testing, knowledge, and management using standardized instruments. The completion rate was 87%.

RESULTS: …

Coronary Steal Syndrome After Coronary Artery Bypass For Anomalous Aortic Origin Of A Coronary Artery., Benjamin A. Youdelman, Glenn J. Pelletier, C Igor Mesia, Marshall L. Jacobs

Department of Surgery Faculty Papers

Anomalous aortic origin of a coronary artery found in a symptomatic 9-year-old boy was initially treated with coronary artery bypass grafting using a left internal mammary artery anastomoses to the left anterior descending coronary artery, but resulted in coronary ischemia, likely from a steal phenomenon. Subsequent transection of the proximal left internal mammary artery with anastomosis to the ascending aorta, and coronary ostial enlargement, resulted in a durable treatment. We recommend caution in choosing coronary artery bypass grafting using a left internal mammary artery pedicle graft for the treatment of anomalous aortic origin of a coronary artery.

Functional Characterization And Protein-Protein Interactions Of Trypanosome Splicing Factors U2af35, U2af65 And Sf1, Martin P. Vazquez, David Mualem, Natalia Bercovich, Michael Zeev Stern, Benson Nyambega, Omer Barda, Dan Masiga, Sachin Kumar Gupta, Shulamit Michaeli, Mariano J. Levin

All Peer-Reviewed Publications

Early in the assembly of the spliceosome of eukaryotes the branch-point binding protein (BBP, also called SF1) recognizes the branch point sequence, whereas the heterodimer U2AF consisting of a 65 and a 35 kDa subunit, contacts the polypyrimidine tract and the AG splice site, respectively. Herein, we identified, cloned and expressed the Trypanosoma cruzi and Trypanosoma brucei U2AF35, U2AF65 and SF1. Trypanosomatid U2AF65 strongly diverged from yeast and human homologues. On the contrary, trypanosomatid SF1 was conserved but lacked the C-terminal sequence present in the mammalian protein. Yeast two hybrid approaches were used to assess their interactions. The interaction between …

Fight Against Chronic Diseases (High Blood Pressure, Stroke, Diabetes And Cancer) In Pakistan; Cost-Effective Interventions, Mohammad Wasay, Abdul Jabbar

Department of Medicine

No abstract provided.

Asian Cerebral Venous Thrombosis Registry: Study Protocolv, Mohammad Wasay, Ayeesha Kamal, Bhojo Khealani

Department of Medicine

Introduction:

Cerebral venous thrombosis (CVT) is a well known but poorly reported entity. Most of the studies and registries related to CVT are reported from European countries. No large multi-center or multi- national data base or registry has been reported from Asian countries. CVT is not uncommon in Asia especially in south Asian subcontinent including India, Pakistan and Bangladesh. One study reported from India that CVT accounted for half of all strokes in the young and 40% of strokes in women. Review of CVT cases from Asian countries is suggestive of differences in risk factors profile and outcome in these …

Moyamoya Disease: A Clinical Spectrum, Literature Review And Case Series From A Tertiary Care Hospital In Pakistan., Sana Shoukat, Ahmed Itrat, Ather M. Taqui, Moazzam Zaidi, Ayeesha Kamran Kamal

Department of Medicine

Background: Moyamoya is a rare cerebrovascular disease of unknown etiology. The data on moyamoya disease from Pakistan is sparse. We report a case series of 13 patients who presented with moyamoya disease to a tertiary care hospital in Pakistan with a national referral base.

Methods: We conducted a retrospective review of thirteen patients who presented to The Aga Khan University and diagnosed with "Moyamoya Disease" during the period 1988 – 2006. These patients were identified from existing hospital database via ICD-9 codes. A predesigned questionnaire containing information about clinical presentation, management and neuroimaging was administered to all identified patients. Results: …

The Effects Of Coloring Books On Children’S Drawings: Implications For Art Therapy, Sarah Elizabeth Garrison

EVMS School of Health Professions Theses & Dissertations

This study aimed to test the effects of coloring books on children’s drawings and relate the findings to art therapy practice. A review of the relevant literature revealed a widely accepted theory of drawing development, in which all individuals pass through a series of sequential stages of drawing. These stages varied slightly from author to author, but were all similar to the originally developed stages of drawing development first outlined by Viktor Lowenfeld (Lowenfeld & Brittain, 1987).

In art therapy, these stages are applied to the drawings of children to assess developmental level. Art is also utilized in art therapy …

Laparoscopic Duodenojejunostomy For Superior Mesenteric Artery Syndrome., Jason D. Fraser, Shawn D. St Peter, Jenevieve H. Hughes, James M. Swain

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Superior mesenteric artery (SMA) syndrome, also called Wilkie's syndrome, is a rare clinical phenomenon believed to be caused by compression of the third portion of the duodenum by the overlying superior mesenteric artery. We present the case of a 32-year-old female who presented with epigastric pain, weight loss, and vomiting.

METHODS: Her workup included a normal upper endoscopy as well as an abdominal CT scan and upper GI contrast study that confirmed the diagnosis of superior mesenteric artery syndrome. The patient was taken to the operating room and underwent successful treatment with laparoscopic duodenojejunostomy.

RESULTS: The patient achieved complete …

Repairing An Implant Titanium Milled Framework Using Laser Welding Technology: A Clinical Report, Soni Prasad, Edward A. Monaco, Jr.

School of Dentistry Faculty Research and Publications

The application of laser welding technology allows titanium to be welded predictably and precisely to achieve accurate fit of a milled framework. Laser energy results in localized heat production, thereby reducing thermal expansion. Unlike soldering, laser energy can be directed to a small area, making it possible to laser weld close to acrylic resin or ceramic. This article describes the use of laser welding to repair an implant titanium milled fixed denture. A quick, cost-effective, accurate repair was accomplished, and the repaired framework possessed adequate strength and the same precise fit as the original framework.

Visual Impairment And Eye Care Among Older Americans: Secondary Analysis Of The Behavioral Risk Factor Surveillance System (Brfss), Amy L. Freeland

Dissertations

The aim of this three-paper format dissertation is to explore three topics relevant to public health and vision loss. The three papers are independent studies, yet build upon each other by first describing the population of people aged 40 years and older in the United States in terms of visual impairment, diagnosed eye disease/injury, and their use of eye care, and then next exploring the factors that influence eye care use for both the general population and the subpopulation of people with diagnosed diabetes. The first paper provides a state-level examination of the characteristics of people aged 40 years and …