Medicine and Health Sciences Commons^™

Potential Mechanisms Explaining The Antitumor Effect Of Total-Body Irradiation, Glen Michael Miller

Loma Linda University Electronic Theses, Dissertations & Projects

While numerous reports have documented that radiation exposure increases the risk for malignancy and suppresses immune mechanisms, increasing evidence has suggested that low-dose total-body irradiation (TBI) may alter leukocyte composition and function leading to heightened immune responsiveness and long-term remission of certain cancers. Having observed that moderate-dose TBI produces an antitumor effect in the Lewis lung carcinoma (EEC) model, the major goal of this study was to determine whether changes in tumor growth could be correlated with radiation-induced alterations of immune system parameters. The governing hypothesis was that selective immune augmentation, i.e. upregulation of specific leukocyte subsets, is primarily responsible …

Cultural And Psychological Influences On Diabetic Adherence, Keikilani Mcmillin-Williams

Loma Linda University Electronic Theses, Dissertations & Projects

Diabetes mellitus is a serious disease that poses a particular healthcare challenge because progression is considered controllable (Cox, et al, 1985; Vinicor, et al, 1996) yet treatment adherence, and thus outcome, is very poor (Gonder-Frederick, Cox, & Ritterband, 2002; Goodall, 1991). Culture is a lethal risk factor for diabetic contraction and treatment maintenance. Latinos within the United States are two-to-three times more likely to develop complications and die than non-Latinos (Haffner et al, 1996; Rubin, Peyrot, & Saudek, 1991) and are less likely to adhere to treatment (Lipton, Losey, Giachello, Mendez, & Girotti, 1998). Efforts to eliminate health disparities have …

Care Management For Persistent Pain: An Introduction, Christine W. Hartmann, Neil I. Goldfarb, Susan S. Kim, Bhaskar R. Nuthulaganti, Raafat Seifeldin

College of Population Health Faculty Papers

Persistent pain is a frequently occurring condition with significant economic, clinical, and humanistic implications, for both individuals and society. Current literature, however, points to unresolved issues with regard to its identification, assessment, diagnosis, and treatment, and a number of suggestions have been made for improving the quality of care for pain sufferers. Because persistent pain shares many of the salient features of other chronic conditions such as diabetes and congestive heart failure, it is reasonable to believe that the adoption of a coordinated approach to care management could substantially improve the quality of care. Several strategiesincluding identification, appropriate referral, education, …

Investigation Of Parental/Caregiver Concerns Of Children With Spasticity, Lynda Johnson-Cross

Masters Theses

Although there is capacious documentation on the concerns associated with parenting/care giving the disabled child, the concerns of parents/caregiver of children with the specific condition of spasticity is lacking. Therefore, the purpose of this study was to begin to determine the concerns of parents/caregivers of children with spasticity as they specifically relate to care giving. An extensive qualitative based survey interview was utilized to gather information from three informants. Analysis revealed clusters of concerns in the Nature of Caregiving, Spasticity Encounters, and Parental/Caregiver Comments.

Long-Term Care: Informed By Research, Francis G. Caro

Gerontology Institute Publications

Health services research has contributed to health policy and service developments that have led to major improvements in the quality of long-term care in the United States. This policy brief highlights a few areas in which publicly and privately funded research has informed the long-term care field.

Systemic Sclerosis: Current Views Of Its Pathogenesis., Chris T. Derk, Sergio A. Jimenez

Department of Medicine Faculty Papers

Systemic sclerosis (SSc) is an autoimmune disorder of unknown etiology characterized by severe and often progressive cutaneous and visceral fibrosis, pronounced alterations in the microvasculature, and numerous cellular and humoral immune abnormalities. Clinically, SSc is very heterogeneous, encompassing a spectrum ranging from mild limited forms of skin sclerosis with minimal internal organ involvement to severe skin and multiple internal organ fibrosis. Mortality and morbidity in SSc are very high and are directly related to the extent of the fibrotic and microvascular alterations. A better understanding of the pathogenesis of this incurable disorder will help to better target and design effective …

Eimeria Zuernii Infection In Thai Native Calves, Komkrich Teankum, Nopadon Pirarat, Manop Moungyai

The Thai Journal of Veterinary Medicine

A 3-month-old, female calf in the Dontan district of Mukdaharn province, showed clinical signs of bloody diarrhoea over a period of 3 days and finally died on April 4, 2001. After necropsy, severe, diffuse, haemorrhagic caeco-colitis and proctitis were markedly evident. Histopathologically, various stages of coccidial development, including schizogony and gametogony, were found in the villous epithelium and the epithelial crypts. Infiltration of lymphocytes, plasma cells, neutrophils and macrophages into the lamina propria, as well as into the submucosa was observed. Another 6-month-old, female calf from a nearby area also showed bloody diarrhoea with mild anorexia and numerous oocysts of …

What Is Your Diagnosis?, Pranee Tuntivanich

The Thai Journal of Veterinary Medicine

No abstract provided.

Inactivation Of Picornaviruses And Caliciviruses Part 1: Biology And Epidemiology, Suphachai Nuanualsuwan, Dean O. Cliver

The Thai Journal of Veterinary Medicine

Foodborne picornaviruses and human calicivirus have one molecule of linear, positive-sense, single-stranded RNA, covered by a capsid without a lipid envelope. These viruses have a spherical shape, a particle diameter of 27-40 nanometers and the triangulation (T=3) icosahedral symmetry of a capsid. The replication cycle of poliovirus (PV) and hepatitis A virus (HAV) occurs in the cytoplasm of the host cell. The viral proteins are synthesized by the translation of RNA after the virus particles attach and uncoat at the host cell membrane. Major translated proteins are structural protein (capsid protein) and functional proteins e.g. proteases and RNAdependent RNA polymerase. …

Antimicrobial Susceptibility Tests On Vibrio Pathogens From Black Tiger Shrimps Penaeus Monodon, Nithawan Jarernporn, Cholthida Bantaokul, Nutcharnart Tipmongkolsilp, Monthon Lertworapreecha, Janenuj Wongtavatchai

The Thai Journal of Veterinary Medicine

The standard, in vitro, minimal inhibitory concentrations (MICs) of 5 antimicrobials; chloramphenicol, ciprofloxacin, enrofloxacin, norfloxacin and nalidixic acid were evaluated against vibrios isolated from diseased black tiger shrimps Penaeus monodon. One hundred and ninety-seven pathogenic vibrio isolates obtained from different shrimp culture areas in Thailand during March 2001-January 2002 were, V. fluvialis (50 isolates, 25.38%), V. damsela (41 isolates, 20.81%), V. vulnificus (39 isolates, 19.80%), V. parahaemolyticus (28 isolates, 14.21%), V. cholerae (25 isolates, 12.69%) and V. alginolyticus (14 isolates, 7.11%). MICs were examined for all the tested antimicrobials and the degree of susceptibility of shrimp vibrio pathogens to each …

Pathological Studies In Thailand On Commercially Valued Fish After Exposure To Crude Cyanotoxin Extract, Piyawat Pholsanong, Achariya Sailasuta, Aparat Mahakhant

The Thai Journal of Veterinary Medicine

Pathological changes in four species of Thai commercially valued fish (age 1-1.5 month), Gunther's walking catfish, Clarius macrocephalus (Gunther), Nile tilapia, Oreochromis niloticus (Linnaeus), Striped catfish, Pangasius hypophthalmus (Sauvage) and common silver barb, Barbodes gonionotus (Bleeker), after exposure to crude cyanotoxin extract, at different concentrations, were investigated. The cyanobacterium, Microcystis aeruginosa, was collected from a fish farm in Pathum Thani province and analyzed using HPLC. Skin, liver and gills were histopathologically examined. The skin showed significant, lesions of irritation and epidermal layers were thickened, by an increase of mucous cells, in the scaled species, Nile tilapia and common silver barb, …

Review Of Molecular Infection Biology: Interactions Between Mircoorganisms And Cells By Jörg Hacker And Jürgen Heesemann, Jeffrey D. Cirillo

School of Veterinary and Biomedical Sciences: Faculty Publications

Pathogenesis is one potential outcome of the constant struggle between host defenses and the desire of microorganisms to acquire a privileged niche. This mutually competitive evolutionary process has resulted in interactions among complex and often elegant systems throughout the course of infections. The complexity of these interactions and the large number of infectious agents that exist makes the introduction of students to infectious diseases, as well as a comprehensive review of the field, an extremely daunting task. This book provides just such a comprehensive and timely description of the field in a manner that is easily understandable and enjoyable to …

Residency Program At Michael E Debakey Department Of Surgery, Baylor College Of Medicine, F Charles Brunicardi

Faculty, Staff and Students Publications

No abstract provided.

Editorial: Are You A Prime Mover?, Kathryn Schroeter

College of Nursing Faculty Research and Publications

No abstract provided.

Donation After Cardiac Death: The Reinvention Of A Forgotten Procedure, Gloria Taylor, Karen Samartan, Kathryn Schroeter

College of Nursing Faculty Research and Publications

No abstract provided.

Inside Unlv, Kevin Force, Gian Galassi, Carol C. Harter, Stuart Mann

Inside UNLV

No abstract provided.

The Influence Of Bolus Volume, Temperature, And Viscosity To Swallowing Function By A Self-Designed Phagometer: A Preliminary Study, Chih-Ming Li, Ming-Feng Li, Po-Lin Kuo, Tyng-Guey Wang, I-Nan Lien

Rehabilitation Practice and Science

”The study aimed to depict the influence of bolus temperature, volume, and viscosity in swallowing function by a self-designed phagometer. Two micro switches were used to detect submental muscle activity and pharyngeal motion. They were anchored on a posterior-type cervicothoracic orthosis with multiple adjustable joints to ensure the well contact between the switch and the skin. The signals detected by micro switches were amplified and recorded. The duration between two waves was defined as swallowing trigger time and used to represent the swallowing function.Ten normal male subjects without clinical evidence of dysphagia were enrolled in this study. The average age …

Caudal Epidural Block For Patients With Acute Low Back Pain, Sen-Wei Tsai, Chorng-Sonq Chou, Wei-Chih Chen, Chin-Teng Chung, Chun-Fu Wang

Rehabilitation Practice and Science

Acute low back pain is a very common disease in Rehabilitation clinics. Although acute low back pain can be successfully treated with epidural block, there is few researches for the efficacy of caudal epidural block on acute low back pain. Seventeen patients with acute low back pain were included and managed with caudal epidural block. The therapeutic effect was evaluated with a 5-point pain rating scale.Pain scale of the seventeen patients reduced from mean 4.59 to 2.12 one hour after CEB. One months later, 7 patients had complete pain relief, 4 patients had 4 points pain scale, 2 patients had …

Combined Femoral Ncuropathy And Obturator Neuropathy In Rheumatoid Arthritis With Cervical Subluxation After Operation, Chen-Lin Kao, Yen-Ho Wang, Shun-Ping Cheng, Yu-Gin Na, Chen-Liang Chou

Rehabilitation Practice and Science

Rheumatoid arthritis is a chronic inflammatory disease. Although it primarily affects joints, systemic involvement is frequent. Lung, skin, blood, cardiovascular system and nerve are often affected. Indeed, involvement of the peripheral nervous system may occur with a variety of clinical patterns.A 67-year-old woman suffered from rheumatoid arthritis for 10 years with regular medical control. Due to bilateral distal parts of hands and feet numbness, and gait disturbance for about 2 months, she was diagnosed of rheumatoid arthritis with C1-C2 subluxation by neurosurgeon. C1-C2 posterior spinal fusion was performed. But, the patient felt left lower extremity weaker than right one then. …

Vessels Occlusion After Wasp Stings: A Casereport And Literature Review, Chi-Chuan Shih, Jue-Long Wang, Shwu-Fen Sun, Po-Tsang Lee, Pei-Der Sheu

Rehabilitation Practice and Science

Allergic reactions to wasp stings range from large local reactions to life-threatening anaphylaxis. Of the anaphylactic shock occurring outside the hospital, wasp stings was concluded to be the second cause following drug allergy. Cerebral infarction and transient ischemic attack have been reported in the setting of acute anaphylactic shock due to wasp stings. However, there are fewer reports about the presentation of large vessels occlusion outside the brain after wasp stings. Here we report on a woman suffering from a stroke and right above-knee amputation after a severe wasp sting. We had a literature review in the light of the …

Cancer In Louisiana: 1996-2000, Volume 17, Louisiana Tumor Registry, Catherine N. Correa, Xiao-Cheng Wu, Patricia A. Andrews, Mei-Chin Hsieh, Vivien W. Chen

Policy & Position Papers

Mission:

To collect and report complete, high-quality, and timely population-based cancer data in Louisiana to support cancer research, control, and prevention.

Vision:

To reduce suffering and death from cancer using information collected by the Louisiana Tumor Registry.

History:

Cancer registration in Louisiana began in 1947 at the Charity Hospital Tumor Registry in New Orleans. In 1974, as part of its Surveillance, Epidemiology and End Results (SEER) Program, the National Cancer Institute provided funds for a population-based cancer incidence and survival registry covering Jefferson, Orleans, and St. Bernard parishes. Five years later, the Louisiana Tumor Registry (LTR) was transferred to the …

Jefferson Alumni Bulletin – Volume 52, Number 3, June 2003

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume 52, Number 3, June 2003 Dean's Column by Dean Thomas J. Nasca ’75, page 4 Update on Transplant Surgery, page 5 The New Jefferson Hospital for Neuroscience and Farber Institute for Neurosciences, page 6 Researchers Show That Human Neural Stem Cells Can Become Dopamine-Making Brain Cells in the Lab, page 8 Evidence of Greater Sensitivity to Addictive Drugs in Adolescence, page 8 New Hope for Patients with Late Stage Parkinson's, page 10 Above and Beyond the Call: Three Alumni Heroes, page 11 The Mother in The Gross Clinic: A Medical Explanation of Her Hand, page …

The Susceptibility Of Thai Native, Mixed Thai Native, Layertype And Broiler Chickens To Infectious Bursal Disease Virus, Thawat Lekdumrongsak, Jiroj Sasipreeyajan

The Thai Journal of Veterinary Medicine

Thai native, mixed Thai native and layer-type chickens, 50 birds of each and forty broiler chickens, were reared separately, to determine the susceptibility of each breed to infectious bursal disease virus (IBDV). All birds received IBDV when 36-days-old, given by oral inoculation. Mortality rates were observed for 10 days. Blood samples were collected on days 36, 39, 42 and 46 and sera were tested by an enzyme-linked immunosorbent assay (ELISA) for IBDV antibodies. Bursa to body weight ratios and histopathological lesion scores were determined when the birds were 36 and 46-days-old. The results revealed that mortality rate of Thai native, …

The First Four Months In A New Foster Placement: Psychosocial Adjustment, Parental Contact And Placement Disruption, James G. Barber, Paul H. Delfabbro

The Journal of Sociology & Social Welfare

Intake and four-month follow-up measures were obtained for 235 children referred into a new foster care placement over a 12-month period in the Australian State of South Australia. Twenty-five percent of the sample returned home within 4-months, and for those who remained in care throughout, there had been modest gains in behavior, psychological adjustment and adjustment at school. On the other hand, there were considerable levels of placement disruption, a high degree of non-compliance with parental visiting plans, and a high proportion of children fell outside ninety-five percent confidence intervals for the general adolescent population on most well-being measures, particularly …

Review Of The Environment: Its Role In Psychosocial Functioning And Psychotherapy. Carolyn Saari. Reviewed By Timothy Page., Timothy Page

The Journal of Sociology & Social Welfare

Book review of Carolyn Saari, The Environment: Its Role in Psychosocial Functioning and Psychotherapy. New York: Columbia University Press, 2002. $49.50 hardcover, $22.00 papercover.

The Use Of Porcine Small Intestinal Submucosa (Psis) In A Canine Deep Corneal Ulcer, Pasakorn Briksawan, Sunti Wongaumnuaykul, Pranee Tuntivanich, Nalinee Tuntivanich, Kumpanart Sunthornvipat

The Thai Journal of Veterinary Medicine

Porcine small intestinal submucosa (PSIS) was used as a graft to repair 13 dogs with deep corneal ulceration. Eight cases had staphyloma and staphyloma associated with hyphema. Two cases had staphyloma associated with glaucoma. There was one case of each of descemetocoele, descemetocoele associated with glaucoma and rupture of the cornea. Ten dogs without glaucoma returned to normal vision (76.93%) with minimal anterior synechia and scarring. Three dogs with associated glaucoma became blind (23.07%). PSIS has been demonstrated to stimulate corneal healing without tissue rejection and is recommended to be used as a graft material to repair deep corneal ulcers …

Cytokine Profiles Following Mycoplasma Hyopneumoniae And Prrsv Co-Infection In Pigs, Roongroje Thanawongnuwech, Eileen L. Thacker

The Thai Journal of Veterinary Medicine

Bronchoalveolar cells collected by lung lavage 28 days post infection (DPI) of negative controls, Mycoplasma hyopneumoniae (M. hyo)-infected, Porcine Respiratory and Reproductive Syndrome virus (PRRSV)-infected and dual-infected pigs, were evaluated for various cytokine mRNA (IL1α, IL1β, IL6, IL8, IL10, IL12, and TNFα). Semiquantitative RT-PCR revealed that IL1β, IL6, IL10 and the IL12 mRNA expression was significantly increased in dual-infected pigs, compared with the negative controls. PRRSV-infected pigs had significantly increased levels of IL10 and IL12 mRNA. The increased IL10 gene expression that was observed in the dual infected pigs may play a role in the potentiation of PRRSV-induced pneumonia by …

The Role Of Immune Cells In The Sow Endometrium During Different Stages Of The Oestrous Cycle And Early Pregnancy, Kampon Kaeoket

The Thai Journal of Veterinary Medicine

Approximately 30%(range 13-49%) of sows are culled due to fertility disturbances. Reproductive failure on farms are due to anoestrus, repeat breeding (regular and irregular return to oestrus), negative pregnancy diagnosis, abortion or failure to farrow. Reproductive problems are often difficult to diagnose. As a diagnostic tool, post-mortem examination (i.e. macroscopically and histologically) of the reproductive organs is useful when sows with reproductive failure are culled. The present review provides information about the distribution of immune cells, both in non-inseminated and inseminated pregnant sows endometrium, in order to be able to differentiate a physiological distribution of immune cells from pathological conditions. …

Ecg Quiz, Chollada Buranakarl, Sumpun Thammacharoen

The Thai Journal of Veterinary Medicine

No abstract provided.

The Effects Of Weaning-To-Oestrus Interval On The Expression Of Oestrus And The Timing Of Ovulation In Sows, Nontakorn Urasopon, Wichai Tantasuparuk, Mongkol Techakumphu

The Thai Journal of Veterinary Medicine

The aim of the present study was to investigate the effects of the weaning-to-oestrus interval (WOI) and parity on the expression of oestrus and the timing of ovulation in crossbred (Large White x Landrace) sows. The detection of pro-oestrus and oestrus was performed every 8 hrs in all sows, by observing the reddening and swelling of the vulva and by applying the back pressure test in the presence of a boar. Ovulation was monitored every 8 hrs using transrectal ultrasonography. The duration of oestrus was 59.1, 59.8 and 65.3 hrs for parities 1, 2 and 3-4, respectively. Parity 1 and …