Medicine and Health Sciences Commons^™

Equine Immunity To Cyathostome Infections, Marie Alexandra Baudena

LSU Doctoral Dissertations

To study the protective responses of cyathostome-infected ponies, two challenges were performed employing animals with different histories of exposure to these parasites. The hypothesis developed and to be tested in these experiments was that ponies that had longer exposure to cyathostome contaminated pastures would express acquired resistance to infection. The assumption behind this hypothesis was that helminth-naïve ponies infected with cyathostomes would eliminate the infection using only innate immune responses. Whereas previously exposed ponies would eliminate the infection with acquired immune responses, and these would be more effective in ponies with longer exposure to cyathostomes. Thus, helminth-naïve animals would acquire …

Susceptibility Of Bacillus Anthracis To Gamma And Cherry Bacteriophage, Preston A. Fulmer

LSU Master's Theses

Bacillus anthracis is a bacterium that causes severe disease mainly in ruminants, but can affect any mammal, including humans. A popular method for the detection of this organism is susceptibility of the bacterial isolate to g bacteriophage. However, to date no study on the resistance of a wide variety of B. anthracis isolates has been conducted. The following study examines the rate of resistance of a wide range of B. anthracis isolates to g phage as well as another phage specific for B. anthracis known as Cherry phage. We also compared susceptibility to phage with another detection method, susceptibility to …

The Effects Of Expansion On Objective And Subjective Benefit In Hearing-Impaired Listeners, Ashley B. Hill

LSU Master's Theses

The present research involves two studies. Twenty hearing-impaired participants were divided into two groups depending on their audiometric data and binaurally fit with the Starkey Endeavour 3211 hearing instruments. Experiment I was designed to determine if the use of expansion technology affected objective and subjective benefit in hearing-impaired listeners. Probe microphone measures were obtained at 40, 50, and 60 dB SPL and with the speaker deactivated to ensure that the expansion feature was functioning. Listener performance was measured in quite using the Connected Speech Test (CST) and in noise using the Hearing in Noise Test (HINT) at 40, 50, and …

Optimal Age At Fostering For The Derivation Of Helicobacter Hepaticus-Free Mice, Kem Boullion Singletary

LSU Master's Theses

Helicobacter hepaticus is well established as an unwanted variable in laboratory rodent colonies. Historically, caesarean section and embryo transfer have been used to derive Helicobacter-free mouse colonies. Neonatal transfer of newborn mice onto Helicobacter-free foster dams was recently reported as an alternative method of deriving Helicobacter-free mice, but until now, the age by which pups must be fostered to remain Helicobacter-free was unknown. The purpose of this study was to determine the age by which mouse pups must be fostered to remain H. hepaticus-free. Beginning on the day of birth, 20 C57BL/6 mice were fostered from H. hepaticus-positive parents onto …

Effectiveness Of Copper-Oxide Wire Particles On The Control Of Haemonchus Contortus In Sheep, Ariane Diane Watkins

LSU Master's Theses

Among the gastrointestinal nematode parasites that cause the most problems to small ruminants, Haemonchus contortus is one of major concern. Currently, the control of H. contortus and others is almost entirely based on the use of anthelmintics. Consequently, anthelmintic resistance has developed worldwide and this has become a serious problem in small ruminant nematode parasite control programs. In view of this, there is a need for alternative control methods. The use of Copper-Oxide Wire Particles (COWP) to help reduce parasite burden is one such alternative. Three trials were conducted to determine the effect of COWP on the reduction of H. …

Developing Risk Assessment Maps For Schistosoma Haematobium In Kenya Based On Climate Grids And Remotely Sensed Data, Kelsey Lee Mcnally

LSU Master's Theses

It is important to be able to predict the potential spread of water borne diseases when building dams or redirecting rivers. This study was designed to test whether the use of a growing degree day (GDD) climate model and remotely sensed data (RS) within a geographic information system (GIS), could be used to predict both the distribution and severity of Schistosoma haematobium. Growing degree days are defined as the number of degrees centigrade over the minimum temperature required for development. The base temperature and the number of GDD required to complete one generation varies for each species. A monthly climate …

The Effect Of High Frequency Amplification On Subjective And Objective Benefit With Digital Hearing Instruments, Erica Lynn Fleck

LSU Master's Theses

The purpose of the present study was to determine whether amplifying beyond 3 kHz was beneficial to the user, whether the benefit was dependent on degree of loss, and whether subjective data reflected the benefit. Seventeen hearing impaired subjects were binaurally fitted with digital hearing instruments. Qualified subjects were divided into two groups, A and B. Group A had a pure tone average (3,4, and 6 kHz), of 55 dBHL or better. Group B had a pure tone average (3,4, and 6 kHz) greater than 55 dBHL but not exceeding 75 dBHL. Each subject was fit with two conditions (upward …

The Development Of Molecular Diagnostics For Breast Cancer, Anna Henrik Israyelyan

LSU Master's Theses

Breast cancer is one of the most common malignancies in women. It continues to be a major burden and cause of death among women worldwide. Molecular oncology is now one of the most promising fields that may contribute considerably to diagnosis of breast cancer and its metastases addressing major problems with early detection, accurate staging, and monitoring of breast cancer patients. The overall objective of these feasibility studies was to contribute to improved diagnosis, prognosis, and prediction of breast cancer disease through the development of reagents and protocols for the use of molecular biological advances and the assessment of the …

The Effect Of Aging On The Immune Response To Vaccination In The Horse, Daniel H. Fermaglich

LSU Master's Theses

Vaccination programs are designed to protect an animal from infection, however, depending upon the age and health of the animal vaccination may not stimulate a protective humoral response. It is possible that, as in the human and mouse models, geriatric equines may be less responsive than their younger counterparts to current vaccination protocols. The purpose of this study was to identify an age related diminution in the primary and secondary immune responses of geriatric horses in response to vaccination. Two groups of horses were sampled. The first group consisted of an open herd of 39 privately owned horses, varying in …

Role Of Endothelin-1 In The Gastrointestinal Tract Of Horses In Health And Disease, Ramaswamy Monickarasi Chidambaram

LSU Doctoral Dissertations

Gastrointestinal tract disease is the leading natural cause of death in horses and horses with ischemic intestinal disease have the greatest mortality. We hypothesized there is basal synthesis of endothelin-1 (ET-1) in the intestinal tract of healthy horses that is likely involved in regulating vasomotor tone, secretion and motility and that ET-1 synthesis increases with gastrointestinal tract disease, which may be involved in the pathophysiology of these disorders. Plasma ET-like immunoreactivity was increased in horses with naturally-acquired gastrointestinal disease, compared with normal horses; values were greatest in horses with large intestinal strangulation obstruction, enterocolitis and peritonitis. There was an association …

Power, Knowledge And Childbirth Practices : An Ethnographic Exploration In Bangladesh, Kaosar Afsana

Theses: Doctorates and Masters

The intent of this study is to explore why and in what ways rural, poor women in Bangladesh adhere to indigenous birth practices and resist cosmopolitan obstetric care. To understand the complexities of childbirth, a multidimensional framework encompassing culture, gender, socio-economic, political economy and historical perspectives is used. I used ethnographic methods to have deeper understanding of childbirth practices predominantly from women's voices, but strengthened by multiple other voices and my observational experiences. I gathered information in Apurbabari village, the adjacent Thana Health Complex and the Medical College Hospital using in-depth interviews and participant observation, in particular.

The Dose Response Effect Of Almonds On Serum Vitamin E, Plasma Lipid Fractions And Erythrocyte Phospholipids, Pera Jambazian

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to determine if two different amounts of almonds added to a heart healthy diet would increase vitamin E concentrations in healthy men and women, and reflect positive fatty acid profiles in serum lipids and erythrocytes. Twenty three subjects participated in a crossover metabolic study for a 14 week period. Subjects consumed one of three diets for 4 weeks each, a control diet, a low almond diet and a high almond diet after a 2 week run-in period. All meals were prepared in the test kitchen, and almonds were added to the experimental diets by …

The Influence Of Slow Calcium-Activated Potassium Channels On Epileptiform Activity In A Neuronal Model Of Pyramidal Cells, Keun-Hang Susan Yang, Piotr J. Franaszczuk, Gregory K. Bergey

Mathematics, Physics, and Computer Science Faculty Articles and Research

An imbalance between excitation and inhibition can play an important role in the generation of epileptiform activity. Experimental evidence indicates that alterations of either synaptic activity or intrinsic membrane properties may contribute to this imbalance. The slow Ca2+ - activated K+ currents (sIAHP) limit neuronal firing rate and excitability and are therefore of great interest for their potential role in epileptogenesis. The sIAHP is found in both excitatory and inhibitory neurons, and its effect on these neurons can influence the network behavior. Simulations show that the increased excitability caused by reduction of inhibition by the sIAHP for inhibitory interneuron generates …

In Pursuit Of Best Practice : Benchmarking Tools And Processes For The Management Of Hazardous Substances In The Workplace, Barry Chesson

Theses: Doctorates and Masters

Many organisations now strive to achieve excellence in various aspects of occupational health and safety. Benchmarking of the techniques and approaches of other organisations is becoming a popular way of bridging gaps and seeking to achieve high levels of performance. There exist many sources of guidance in the form of external and internal standards, regulations, codes of practice, publications by professional institutions and similar. However, there are clear shortfalls in terms of tools and processes needed to identify areas of opportunity and to overcome barriers to the efficient transfer of ideas and techniques from one enterprise to another. This is …

Occupational Hazards And Radiation Safety In Veterinary Practice Including Zoo Veterinary Practice In Australia, Joseph S. Jeyaretnam

Theses: Doctorates and Masters

This thesis contains reviews and research on the occupational hazards of zoo veterinary practitioners in Australia. Although occupational hazards have long been recognised in the veterinary profession, little information is available on the number and magnitude of injuries to veterinarians in Australia, the United Kingdom or the United States. Apart from anecdotal accounts and some limited data, most of the available information is on occupational zoonoses, generally well recognized by veterinarians. Other occupational hazards to which veterinarians are exposed have received scant attention. The veterinary practitioner in a zoo environment has to treat a range of captive wild species which …

A Phenomenological Inquiry Into The Patient's Experience Of The External Application Of Ginger, Tessa C. Therkleson

Theses: Doctorates and Masters

This Research Study explores the quality of the experience for the patient of the external application of ginger using a Husserllan phenomenological methodology, In this Study the phenomenon Is the patient's experience of the external application of ginger. A group of Anthroposophical Nurses in the Hawkes Bay of New Zealand personally selected seven appropriate consenting adults to receive one external application of ginger. Following their experience, the patients were asked a series of open-ended questions by the researcher, These Interviews were audio taped. The interview data have been transcribed and reduced to themes that have been explored and reflected on …

Clarifying The Lower Incidence Of Birth Defects In The Midwest Of Western Australia : A Study Using Capture Re-Capture Methodology, Donna Baker

Theses: Doctorates and Masters

In April 2000 the Western Australian Birth Defects Registry held its 20th Anniversary Scientific Symposium to signify the first 20 years of the Birth Defects Registry in Western Australia. At the Symposium, significant trends and occurrences in birth defects within Western Australia over the past 20 years were addressed. One factor highlighted in the Registry's 1980-1999 report was that birth defects were reported less frequently in rural regions compared with metropolitan areas. Data collected from the metropolitan area is considered by the Birth Defects Registry to be the most accurate. Therefore, incidence rates of birth defects in this area arc …

Fall Risk Assessment : A Prospective Investigation Of Nurses' Clinical Judgement And Risk Assessment Tools In Predicting Patient Falls In An Acute Care Setting, Helen Myers

Theses: Doctorates and Masters

Falls are a significant problem in acute care, hospital settings, and can have serious consequences, especially for older patients. Fall prevention has therefore been recognised as an important area for research and intervention. In order to target interventions and use resources effectively, a major strategy of many fall prevention programmes has been the development and/or use of risk assessment tools to identify patients who are at high risk of falling. Although many tools have been developed, few have been rigorously tested, and there is currently no evidence to support the clinical utility of fall risk assessment tools. There is a …

Good Life In The Balance: A Cross-National Study Of Dutch And Australian Disability Perspectives On Euthanasia And Physician-Assisted Suicide, Erik A. Leipoldt

Theses: Doctorates and Masters

This is a cross-national qualitative study with the purpose of obtaining perspectives held by people with quadriplegia and leading figures in disability movements in the Netherlands and Australia on the issues of euthanasia and physician-assisted suicide (EPAS). A disability voice is not prominent in public debate on EPAS in Australia or the Netherlands, even though people with disabilities are often thought to be vulnerable in relation to EPAS policies. Disability perspectives are potentially valuable in illuminating issues in relation to euthanasia and physician-assisted suicide, because issues of dependence, independence, and individual autonomy play important roles in relation to both EPAS …

Quality Assessment Of A Collaborative Approach For Decreasing Drug-Related Morbidity And Achieving Therapeutic Goals, Brian J. Issetts, Lawrence M. Brown, Stephen W. Schondelmeyer, Lois A. Lenarz

Pharmacy Faculty Articles and Research

Background Collaboration between physicians and pharmacists is one approach to address drug-related morbidity and achieve therapeutic goals. A collaborative practice of pharmaceutical care has been used in the Fairview Clinics System of Minneapolis-St Paul since 1999.

Methods The quality of therapeutic determinations made by pharmacists within this collaborative practice of pharmaceutical care was studied by a 12-member panel of physicians and pharmacists who used randomly selected patient records. This was a quality improvement and care process validation component of a study evaluating the effects of drug therapy management in patients receiving prepaid medical assistance. An implicit review process was used …

Laman Web Kanser Servikal, Yussof Nadia

Student Works (2000-2009)

Kanser servikal merupakan penyakit kedua terbesar yang menyerang wanita di seluruh dunia. Bagi memberi kesedaran betapa bahayanya penyakit ini jika ia menyerang wanita, maka laman web kanser seryikal dibangunkan. Laman web kanser servikal ini berperanan sebagai suatu sumber rujukan maklumat mengenai kanser servikal bagi orang ramai khususnya golongan wanita. Dengan adanya laman web ini, diharapkan akan meningkatkan kesedaran dan pengetahuan mengenai penyakit tersebut Selain daripada itu, pengguna boleh mendapatkan maklumat berkaitan simptom, rawatan atau diagnosis dengan mudah dan cewt. Laman web ini juga menyediakan senarai organisasi dan pusat-pusat perubatan yang terdapat di Malaysia yang boleh membantu secara tidak langsung. Pengguna …

Angiotensin Ii Enhances Adenylyl Cyclase Signaling Via Ca2+/Calmodulin. Gq-Gs Cross-Talk Regulates Collagen Production In Cardiac Fibroblasts, Rennolds S. Ostrom, Jennifer E. Naugle, Miki Hase, Caroline Gregorian, James S. Swaney, Paul A. Insel, Laurence L. Brunton, J. Gary Meszaros

Pharmacy Faculty Articles and Research

Cardiac fibroblasts regulate formation of extracellular matrix in the heart, playing key roles in cardiac remodeling and hypertrophy. In this study, we sought to characterize cross-talk between Gq and Gs signaling pathways and its impact on modulating collagen synthesis by cardiac fibroblasts. Angiotensin II (ANG II) activates cell proliferation and collagen synthesis but also potentiates cyclic AMP (cAMP) production stimulated by β-adrenergic receptors (β-AR). The potentiation of β-AR-stimulated cAMP production by ANG II is reduced by phospholipase C inhibition and enhanced by overexpression of Gq. Ionomycin and thapsigargin increased intracellular Ca2+ levels and potentiated isoproterenol- and forskolin-stimulated cAMP production, whereas …

Signaling And Regulation Of G Protein-Coupled Receptors In Airway Smooth Muscle., Charlotte K Billington, Raymond B Penn

Department of Medicine Faculty Papers

Signaling through G protein-coupled receptors (GPCRs) mediates numerous airway smooth muscle (ASM) functions including contraction, growth, and "synthetic" functions that orchestrate airway inflammation and promote remodeling of airway architecture. In this review we provide a comprehensive overview of the GPCRs that have been identified in ASM cells, and discuss the extent to which signaling via these GPCRs has been characterized and linked to distinct ASM functions. In addition, we examine the role of GPCR signaling and its regulation in asthma and asthma treatment, and suggest an integrative model whereby an imbalance of GPCR-derived signals in ASM cells contributes to the …

Perceived Motivational Factors Among Allied Health Managers And Subordinates, Sandra Barker Dunbar

Internet Journal of Allied Health Sciences and Practice

This exploratory study sought to assess the differences in perceptions among allied health managers and subordinates regarding motivation in the workplace due to a paucity of literature in this area. With an increased demand for higher productivity, an ever-changing health care system and managed care restrictions, it is also important to understand what may motivate individuals who are functioning within different work environments than in the past. The hygiene and motivator factors from Herzberg’s two factor theory created the independent variables which overlap with Maslow’s Hierarchy of Needs descriptions. These included Basic (job security, salary etc.), Safety (work conditions, pension), …

Model For Clinical Education In Athletic Training, Jeff G. Seegmiller

Internet Journal of Allied Health Sciences and Practice

Clinical education is an intrinsic part of most allied health educational programs. However, conceptual models differ as to what constitutes quality for clinical experiences. As a relatively new allied health care field, athletic training education is adapting in order to meet the needs of a changing health care environment. Recent initiatives for clinical education mark the change from a quantitative (hours of exposure) approach, to one emphasizing quality (mastery over time). However, in this transition from field-based to curriculum emphasis, the coherence between different aspects of the educational process have weakened. This paper presents a background of clinical education in …

Physician Assistant Programs In The U.S., Stephan M. Cohen

Internet Journal of Allied Health Sciences and Practice

The Association of Physician Assistant Programs (APAP) released the 18th Annual Report on Physician Assistant Educational Programs for the years 2001-2002 in the Winter of 2002. The annual report is the most comprehensive view of physician assistant educational programs produced today and gives great insight into the Physician Assistant system of education. The Association of Physician Assistant Programs serves as the national organization representing physician assistant educational programs in the United States. This article will review the highlights of this study.

Teaching, Practice, And Research: An Integrative Approach Benefiting Students And Faculty, Jacqueline Fawcett, Cynthia Aber, Marianne E. Weiss

College of Nursing Faculty Research and Publications

A project showing the integration of teaching, practice, and research is described. The project involved using information gathered as part of baccalaureate nursing students' assessments of women's perceptions of and responses to cesarean birth to extend a program of nursing research. Benefits to student learning and faculty research programs are identified. The project serves as a prototype for the teaching, practice, and research activities of all students and faculty in nursing and other professional disciplines.

An Analysis Of The Majority Report “Responsible Parenthood” And Its Recommendations On Abortion, Sterilization And Contraception, Richard J. Fehring

College of Nursing Faculty Research and Publications

This paper will focus on the majority report (titled “Responsible Parenthood”) of the 1966 Papal Birth Control Commission and its recommendations on abortion, sterilization, and contraception.(1) The analysis is made with the hindsight and perspective of thirty-seven years of scientific data on fertility, family planning, and family life. The analysis presented here does not concern the whole document but rather focuses on what are called the “objective criteria” that were provided in the document to help married couples make decisions on the use of contraception. While acknowledging the intellectual abilities and expertise of those who wrote the majority report, the …

Te Contaria Mi Vida: I Would Tell You My Life, If Only You Would Ask, Ruth Ann Belknap, Pilar Sayeed

College of Nursing Faculty Research and Publications

Universal screening for domestic violence is recommended in many health care settings. This qualitative study was undertaken to explore the thoughts and feelings of Mexican American women regarding being asked questions about domestic violence by a health care provider. We wanted to further explore what characteristics about a nurse, or other health care provider, would give a woman confianza, the trust necessary to discuss this issue. Seven women, who self identified as abused or formerly abused, were recruited from a pool of Spanish-speaking women receiving services from a rural domestic violence agency in the midwestern United States. The researchers …

The Benefits Of Nurse-Led Secondary Prevention Clinics For Coronary Heart Disease Continued After 4 Years, A Commentary, Marilyn Frenn

College of Nursing Faculty Research and Publications

No abstract provided.