Medicine and Health Sciences Commons^™

The Comparative Effects Of 0.12% Chlorhexidine And An Herbal Oral Rinse On Dental Plaque-Induced Gingivitis, Elizabeth N. Southern

Dental Hygiene Theses & Dissertations

The purpose of this study was to determine the effects of 0.12% chlorhexidine rinse (CID{) and herbal rinse (HBR) to placebo, on gingival health status over time. Methods: 63 subjects (57% male, 43% female, mean age 25 years, sd=7.67) were randomly assigned to one of three treatment groups; CHX, HBR, or placebo. Subjects rinsed twice daily (AM and PM) with ½ ounce of allocated rinse, after brushing and flossing, for three months. Subjects were given the same type of soft bristle toothbrush and whitening toothpaste. Participants were advised to refrain from use of any other oral rinse for the duration …

Characterization Of Spy1600 A Putative Hyaluronidase Gene In Group A Streptococci, Karin M. Berling

Biological Sciences Theses & Dissertations

Group A Streptococci (GAS), also known as Streptococcus pyogenes, can cause a variety of human diseases ranging from asymptomatic to life threatening. Exactly how a single type of organism is able to inflict such a multitude of diseases remains to be fully understood. One possibility includes the large number of secreted virulence factors expressed by the organism. The recent sequencing of three streptococcal genomes has indicated the existence of several previously unknown genes, some of which may encode possible virulence factors. Among these is Spy1600, which based on its sequence similarities has been proposed to encode a hyaluronidase, a …

Clergy Sexual Abuse And The Catholic Church: What Do We Know And Where Do We Need To Go?, Thomas G. Plante

Psychology

Few recent topics have received the kind of media attention, heated debate, and discussion than the topic of sex-offending clergy, their victims, and supervisors. It is a story about too many bishops (and priests) behaving badly when they are purported to be the moral, religious, and ethical leaders of society. It is a remarkable story. However, it is a complex story that has had little scholarship and discourse driven by thoughtfulness, civility, and reason.

Renal Carcinoid Tumour, Z Ahmad, N Yaqoob, S Muzaffar, A S. Hussainy, S H. Hasan

Department of Pathology and Laboratory Medicine

No abstract provided.

Renal Teratoma: A Rare Entity, N Yaqoob, Z Ahmed, N Jafri, S Muzaffar, S H. Hasan

Department of Pathology and Laboratory Medicine

No abstract provided.

Phonological Awareness In Spanish: A Tutorial For Speech-Language Pathologists, Brenda K. Gorman, Ronald B. Gillam

Speech Pathology and Audiology Faculty Research and Publications

In the United States, more than 2 million children in Grades pre-K through 6 speak Spanish as their primary language. Approximately 50% of these students receive academic instruction in Spanish. This tutorial provides research-based recommendations for presenting phonological awareness tasks to children who receive literacy instruction in Spanish. The authors also discuss how phonological awareness development may differ between monolingual children learning Spanish and monolingual children learning English, and the implications of these differences for choosing appropriate phonological awareness tasks for Spanish speakers.

Tomographic Reconstruction Of Treponemal Cytoplasmic Filaments Reveals Novel Bridging And Anchoring Components, Jacques Izard, Bruce F. Mcewen, Rita M. Barnard, Thomas Portuese, William A. Samsonoff, Ronald J. Limberger

Department of Food Science and Technology: Faculty Publications

An understanding of the involvement of bacterial cytoplasmic filaments in cell division requires the elucidation of the structural organization of those filamentous structures. Treponemal cytoplasmic filaments are composed of one protein, CfpA, and have been demonstrated to be involved in cell division. In this study, we used electron tomography to show that the filaments are part of a complex with a novel molecular organization that includes at least two distinct features decorating the filaments. One set of components appears to anchor the filaments to the cytoplasmic membrane. The other set of components appears to bridge the cytoplasmic filaments on the …

A Diagnostic Strategy To Determine The Shiga Toxin-Producing Escherichia Coli 0157 Status Of Pens Of Feedlot Cattle, David R. Smith, J.T. Gray, Rodney A. Moxley, S.M. Younts-Dahl, M.P. Blackford, S. Hinkley, L.L. Hungerford, C.T. Milton, Terry J. Klopfenstein

School of Veterinary and Biomedical Sciences: Faculty Publications

Although cattle are reservoirs, no validated method exists to monitor Shiga toxin-producing Escherichia coli 0157 (STEC 0157) on farms. In 29 Midwestern United States feedlot pens we compared culturing feces from the individual cattle to: (1) culturing rope devices that cattle rub or chew; and (2) culturing a composite of fecal pats. Eighty-six per cent (68-96 %) of pens were classified correctly using rope devices to detect pens with at least 16 % of the cattle shedding STEC 0 157 [sensitivity = 82 % (57-96 %); specificity = 92 % (62-100 %)]. Ninety per cent of pens (73-98 %) were …

Herpes Simplex Virus Type 2 Induces Rapid Cell Death And Functional Impairment Of Murine Dendritic Cells In Vitro, Clinton J. Jones, M. Fernandez, K. Herc, L. Bosnjak, M. Miranda-Saksena, R. A. Boadle, A. Cunningham

School of Veterinary and Biomedical Sciences: Faculty Publications

Dendritic cells (DC) are critical for stimulation of naive T cells. Little is known about the effect of herpes simplex virus type 2 (HSV-2) infection on DC structure or function or if the observed effects of HSV-1 on human DC are reproduced in murine DC. Here, we demonstrate that by 12 h postinfection, wild-type (wt) HSV-2 (186) abortively infected murine bone marrow-derived DC and induced early cell death compared to UV-inactivated HSV-2 or mock-infected DC. HSV-2-induced loss of DC viability was more rapid than that induced by HSV-1 and was due, in part, to apoptosis, as shown by TEM, caspase-3 …

The Gene That Encodes The Herpes Simplex Virus Type 1 Latency-Associated Transcript Influences The Accumulation Of Transcripts (Bcl-XL And Bcl-XS) That Encode Apoptotic Regulatory Proteins, Weiping Peng, Gail A. Henderson, Guey-Chuen Perng, Anthony B. Nesburn, Steven L. Wechsler, Clinton J. Jones

School of Veterinary and Biomedical Sciences: Faculty Publications

The herpes simplex virus type 1 latency-associated transcript (LAT) inhibits apoptosis. We demonstrate here that LAT influences the accumulation of the Bcl-x_L transcript versus the Bcl-x_S transcript in Neuro-2A cells. Bcl-x_L encodes an antiapoptotic protein, whereas Bcl-x_S encodes a proapoptotic protein. Promoting the accumulation of Bcl-x_L in neurons may inhibit apoptosis, thus enhancing the latency-reactivation cycle.

Physical Activity And Stroke Risk: A Meta-Analysis, Chong Do Lee, Aaron R. Folsom, Steven N. Blair

Faculty Publications

Background and Purpose - Whether physical activity reduces stroke risk remains controversial. We used a meta-analysis to examine the overall association between physical activity or cardiorespiratory fitness and stroke incidence or mortality.

Methods - We searched MEDLINE from 1966 to 2002 and identified 23 studies (18 cohort and 5 case-control) that met inclusion criteria. We estimated the overall relative risk (RR) of stroke incidence or mortality for highly and moderately active individuals versus individuals with low levels of activity using the general variance-based method.

Results - The meta-analysis documented that there was a reduction in stroke risk for active or …

Inside Unlv, Cate Weeks, Diane Russell, Carol C. Harter, Martin Watson

Inside UNLV

No abstract provided.

Unlv Magazine, Barbara Cloud, Jennifer Vaughan

UNLV Magazine

No abstract provided.

Il-7 Enhances Peripheral T Cell Reconstitution After Allogeneic Hematopoietic Stem Cell Transplantation., Onder Alpdogan, Stephanie J Muriglan, Jeffrey M Eng, Lucy M Willis, Andrew S Greenberg, Barry J Kappel, Marcel R M Van Den Brink

Department of Medical Oncology Faculty Papers

We used clinically relevant murine allogeneic bone marrow transplantation (BMT) models to study the mechanisms by which IL-7 administration can improve posttransplant peripheral T cell reconstitution. After transplant we could distinguish two populations of mature donor T cells: (a) alloreactive T cells with decreased expression of CD127 (IL-7 receptor alpha chain) and (b) nonalloreactive T cells, which express CD127 and undergo homeostatic proliferation. IL-7 administration increased the homeostatic proliferation of nonalloreactive T cells, but had no effect on alloreactive T cells and the development of graft-versus-host disease. Allogeneic transplant of purified hematopoietic stem cells and adoptive transfer of thymocytes into …

Candida Esophagitis: Risk Factors In Non-Hiv Population In Pakistan, Javed Yakoob, Wasim Jafri, Shahab Abid, Nadim Jafri, Muhammad Islam, Saeed Hamid, Hasnain Ali Shah, Akbar S. Hussainy

Section of Gastroenterology

AIM:

Candida esophagitis is a frequent infection in immunocompromised patients. This study was designed to determine its characteristics in non- human immune deficiency virus (HIV) infected patients attending a teaching hospital.

METHODS:

Clinical records of all patients coded by international classification of diseases 9th revision with clinical modifications' (ICD-9-CM), with candida esophagitis diagnosed by esophagogastroduodenoscopy (EGD) and histopathology over a period of 5 years were studied.

RESULTS:

Fifty-one patients (27 males, 24 females, range 21-77 years old and mean age 52.9 years) fulfilled the criteria (0.34% of the EGD). The common predisposing factors were carcinoma (OR 3.87, CI 1.00-14.99) and …

Multijurisdictional Approach To Biosurveillance, Kansas City., Mark A Hoffman, Tiffany H Wilkinson, Aaron Bush, Wayne Myers, Ron G Griffin, Gerald L Hoff, Rex Archer

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.

Ua66/1/5 Applied Research & Technology Program Newsletter, Issue 1, Wku Applied Research & Technology Program

WKU Administration Documents

Newsletter created by and about the Applied Research & Technology Program.

Dually Eligible For Medicare And Medicaid: Two For One Or Double Jeopardy?, Jennifer Ryan, Nora Super

National Health Policy Forum

This issue brief describes the characteristics of the population of individuals known as “dual eligibles,” who are eligible for health insurance coverage through both Medicare and Medicaid. It also looks at the differences between “full Medicaid” and “supplemental Medicaid” dual eligibles and the ongoing challenges associated with enrollment and eligibility, integration and coordination, and managed care. The paper presents several examples of integrated care programs designed to better serve the dual-eligible population, including the Program of All-Inclusive Care for the Elderly, Evercare, social health maintenance organizations, and state/federal initiatives such as the Wisconsin Partnership Program, Texas STAR+PLUS, and others. Finally, …

Flexible Recording/High Energy Electrode Catheter With Anchor For Ablation Of Atrial Flutter By Radio Frequency Energy, Chien-Suu Kuo, John G. Gurley

Internal Medicine Faculty Patents

An electrode catheter is provided having a predetermined flexibility throughout the entire length or at least at the contact portion, such as the electrode region, to allow for the molding of the contact portion such that it conforms to the shape of the heart at a preselected desired target area, such as the isthmus between the inlet of inferior vena cava and posterior tricuspid annulus. The catheter also includes a guiding sheath that is preferably semirigid and may be pre-shaped with at least one bend or angulation to assist in molding to ensure that the electrode region overlies the desired …

Campbell, Jacqueline Interview For The Miami Valley College Of Nursing And Health Oral History Project, Carol Holdcraft, Jacqueline Campbell

Wright State University - Miami Valley College of Nursing and Health Oral History Project

Carol Holdcraft interviewed Jacqueline Campbell on September 23, 2003 about the founding of Wright State University College of Nursing and Health. In the interview, Campbell discusses her career and her decision to come to Wright State as a student for the College of Nursing and Health.

Incremental Bar Admission: Lessons From The Medical Profession, Jayne W. Barnard, Mark Greenspan

Journal of Legal Education

No abstract provided.

Research News: 2003, No. 3, University Of Mississippi. School Of Pharmacy

Research News: Grants and Publications (2000-2014)

Grants, publications, technology transfer, special announcements

Medical Response For Terrorist And Public Health Threats: One Region's Experience (Pittsburgh), Eileen Salinsky, Lisa Sprague

National Health Policy Forum

This site visit, planned and convened in conjunction with the Agency for Healthcare Research and Quality’s User Liaison Program, examined the efforts underway in the greater Pittsburgh area to develop emergency medical response capabilities for mass causality events. The site visit explored efforts to improve infectious disease surveillance capabilities and looked at the Region 13 collaborative’s development of a regionalized approach to emergency management planning and response. Hospital preparedness activities were also studied, including a discussion of lessons learned from a recent drill to test response to a radiological event and an exploration of conceptual frameworks to guide hospital planning …

Adolescent Religiosity And Sexuality: An Investigation Of Reciprocal Influences, Sam A. Hardy, Marcela Raffaelli

Department of Psychology: Faculty Publications

The present study examined potential bi-directional associations between religiosity and first sexual intercourse. The sample, drawn from the National Longitudinal Survey of Youth, included 303 teens (22% Hispanic, 35% Black, 43% White; 53% male) aged 15–16 in 1996 and 17–18 in 1998. All teens included in the sample were virgins at Time 1. In the longitudinal analyses, higher Time 1 religiosity (a composite of importance of religion and frequency of church attendance) was associated with a lower likelihood of first sexual intercourse between Time 1 and Time 2. However, transition to sexual activity between Time 1 and Time 2 was …

Rifn-Gamma-Mediated Growth Suppression Of Platinum-Sensitive And -Resistant Ovarian Tumor Cell Lines Not Dependent Upon Arginase Inhibition, Bohuslav Melichar, Wei Hu, Rebecca Patenia, Karolina Melicharová, Stacie T Gallardo, Ralph Freedman

Faculty, Staff and Student Publications

BACKGROUND: Arginine metabolism in tumor cell lines can be influenced by various cytokines, including recombinant human interferon-gamma (rIFN-gamma), a cytokine that shows promising clinical activity in epithelial ovarian cancer (EOC). METHODS: We examined EOC cell lines for the expression of arginase in an enzymatic assay and for transcripts of arginase I and II, inducible nitric oxide synthase (iNOS), and indoleamine 2,3-dioxygenase (IDO) by reverse transcription-polymerase chain reaction. The effects of rIFN-gamma on arginase activity and on tumor cell growth inhibition were determined by measuring [3H]thymidine uptake. RESULTS: Elevated arginase activity was detected in 5 of 8 tumor cell lines, and …

Medical Education Digest, Vol. 5 No. 5 (September 15, 2003), Nova Southeastern University

Medical Education Digest

No abstract provided.

Ada News - 09/15/2003, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

A Null Mutation For Tissue Inhibitor Of Metalloproteinases-3 (Timp-3) Impairs Murine Bronchiole Branching Morphogenesis., Sean E Gill, M Cynthia Pape, Rama Khokha, Andrew J Watson, Kevin J Leco

Obstetrics & Gynaecology Publications

Tissue inhibitors of metalloproteinases (TIMPs) regulate extracellular matrix (ECM) degradation by matrix metalloproteinases (MMPs). We have examined the role of TIMP-3 on ECM homeostasis and bronchiole branching morphogenesis during murine embryogenesis. Employing an in vitro organ culture system, we found decreased bronchiolar branching in null lungs when compared with wild type (WT) counterparts after 2 days in culture. When a synthetic inhibitor of MMPs at low dose was added to the culture system, branching was augmented regardless of genotype. Gelatin and in situ zymography revealed that null lungs exhibited enhanced activation of MMPs throughout lung development. We analysed the impact …

Shaping Public Programs Through Medicare, Medicaid, And Schip Waivers: The Fundamentals, Cynthia Shirk

National Health Policy Forum

This background paper examines the use of research, demonstration, and program waiver authorities to test new approaches to the delivery of and payment for health care services in federally financed health coverage programs such as Medicare, Medicaid, and the State Children’s Health Insurance Program. The paper also looks at the mechanics of waivers as well as their history and political context in shaping public programs. In addition, it explores the ways the changing state-federal relationship and the ever-growing demand for state flexibility have driven waiver policy.

Effects Of Chronic Caffeine Pre-Exposure On Conditioned And Unconditioned Psychomotor Activity Induced By Nicotine And Amphetamine In Rats, M. I. Palmatier, E. Y. K. Fung, Rick A. Bevins

Department of Psychology: Faculty Publications

Three experiments examined the effects of chronic preexposure to caffeine on the subsequent conditioned and unconditioned locomotor activating effects of nicotine or amphetamine in rats. Rats were given daily intraperitoneal injections of caffeine anhydrous (0, 10 or 30 mg/kg base) for 30 days. Conditioning (environment-drug pairings) began after the last day of caffeine pre-exposure. Preexposure to 30 mg/kg of caffeine enhanced the acute and chronic locomotor effects of amphetamine (0.5 mg/kg). A similar enhancement of activity was not seen with the high (0.421 mg/kg base) or low dose (0.175 mg/kg) of nicotine. In a drug-free test, the distinct environment paired …