Medicine and Health Sciences Commons^™

Final Report On Evaluation Of Indian Health Service Funded Community Alcohol Service Programs., Indian Health Service

Native Health Database Full Text

The IHS Strategic Plan is the product of a diverse workgroup with expertise in various facets of healthcare from clinical care to facilities construction. The IHS Strategic plan entails four goals: Build Healthy Communities, Achieve Parity in Access by 2010, Provide Compassionate Quality Health Care, and Embrace Innovation. Each of these goals are outlined alongside their respective strategies for accomplishment.

Cancer Mortality Among American Indians And Alaska Natives: Regional Differences, 1994-1998, D.K. Espey, R.E. Paisano, N. Cobb

Native Health Database Full Text

This monograph delineates cancer mortality rates among American Indians and Alaska Native within the different regions served by the Indian Health Service (IHS). The table and charts depict broader geographic regions than in previous IHS cancer mortality monographs. The estimated IHS service population for each region and the cancer mortality rates from 1994 to 1998 are presented. Comparisons are made to the general U.S. population for the same time period. The intention of this publication is to provide detailed information about thew impact of cancer among Native American peoples, with a focus on the regional variability of cancer incidence for …

Male Condom Use In Tanzania: Results From A National Survey, Joe Lugalla, Saidi Kapinga

Institute for Educational Development, East Africa

Objective: To determine factors associated with male condom use in Tanzania.

Methods: Data from the 1996 Tanzania Demographic and Health Survey (TDHS) was used.

In this survey, a national representative sample of sexually active men (N= 1898) and women (N=7027) were interviewed to obtain information about potential predictors of sexual practices and condom use.

Results: Two hundred and ninety (4.1%) women and 288 (15.2%) men had used condoms during their last sexual encounter. Men aged 20-24 years and women aged 15-19 years reported the highest rate of condom use. In both men and women, condom use increased with increasing level …

Osteopathic Medical Education Program Brochure, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Hypertonic Stress Co-Stimulates T Cell Il-2 Expression Through A Feedback Mechanism Involving Atp Release And P2 Receptor Activation Of P38 Map Kinase, William H. Loomis, Sachiko Namiki, Rennolds S. Ostrom, Paul A. Insel, Wolfgang G. Junger

Pharmacy Faculty Articles and Research

Hypertonic stress (HS) can alter the function of mammalian cells. We have reported that HS enhances differentiated responses of T cells by increasing their ability to produce interleukin (IL)-2, a finding of clinical interest because hypertonic infusions may modulate immune function in patients. HS shrinks cells and mechanically deforms membranes, which results in ATP release from many cell types. Here we investigate if ATP release is an underlying mechanism through which HS augments T cell function. We found that mechanical stress and HS induced rapid ATP release from Jurkat T cells. HS and exogenous ATP mobilized intracellular Ca2+, activated p38 …

Long Term Follow-Up Of A Controlled Study To Facilitate Ssi Benefits: Final Report, Michael G. Dow, Timothy Boaz, Sonal Pathak

Mental Health Law & Policy Faculty Publications

No abstract provided.

The Medicaid Involuntary Commitment Project, Annette Christy, Paul G. Stiles, Sonal Pathak

Mental Health Law & Policy Faculty Publications

The Florida Agency for Health Care Administration (AHCA) has contracted with the Louis de la Parte Florida Mental Health Institute (FMHI) to a study short term involuntary or "Baker Act" examinations for Medicaid enrollees and their service utilizations of services reimbursed by Medicaid. This report presents the questions and methodological approaches that were used in this examination Baker Act and Medicaid data for these individuals.

Triad Women’S Project: Group Treatment Manual, Colleen Clark, Fred Fearday

Mental Health Law & Policy Faculty Publications

No abstract provided.

Managing At-Risk Juvenile Offenders In The Community: Putting Evidence Based Principles Into Practice, Randy Borum

Mental Health Law & Policy Faculty Publications

More than a half-million juveniles are under community supervision as a result of violent or delinquent behavior. Research has shown that treatment can reduce their risk of reoffending. This article reviews and distills the key lessons from hundreds of empirical studies and metaanalyses and applies them to practice. The author argues for conducting systematic and developmentally informed risk assessments, selectively assigning intensive intervention to the highest risk offenders, focusing on criminogenic treatment targets, using proven interventions and treatment strategies, and applying rigor in implementation and follow-up.

Experimental Channel Catfish Virus Infection Mimics Natural Infection Of Channel Catfish, Robin L. Stingley, Wayne L. Gray, Billy R. Griffin, Reid Landes

Journal of the Arkansas Academy of Science

Channel catfish virus (CCV) causes a severe hemorrhagic disease in channel catfish fry and fingerlings. CCV epizootics are associated with elevated water temperatures and high mortality rates. Survivors of acute disease are latently infected with i virus. In this study, we investigated conditions effecting CCV pathogenesis and latency utilizing an experimental immersion model to simulate natural infection and a population of Arkansas catfish verified to have no prior CCV exposure, the results indicate that the Auburn- 1 laboratory strain is comparable to CCV field isolates in virulence and ability to establish latent infection. The study confirms that water temperature and …

Creating Art Psychotherapy Training In Australia, John Henzell

'INSCAPE' - ARTCAP November 13-16, 2003

No abstract provided.

Inscape : Symposium Concerning The Arts In Psychotherapy, Deidre Gorrie

'INSCAPE' - ARTCAP November 13-16, 2003

No abstract provided.

Spirituality And Therapy : Reflecting On The Role Of The Therapist, George E. Trippe

'INSCAPE' - ARTCAP November 13-16, 2003

Following on from the conversation in the public forum at the ARTCAP Symposium, I want to reflect briefly on the role of the therapist, in the therapeutic encounter, in the client’s development of his or her spirituality. I assert that the therapeutic encounter is a spiritual process that serves the development of the spirituality of the client. This is in no way a denial of the clinical nature of our therapeutic work, but an attempt to place clinical methods, strategies, insights and practices in a larger, more comprehensive framework of a deep and transformative spiritual process.

Surely I Am In The Wrong Place?, Holly Edworthy

'INSCAPE' - ARTCAP November 13-16, 2003

No abstract provided.

The Greatest Mystery, Katherine Papas

'INSCAPE' - ARTCAP November 13-16, 2003

No abstract provided.

Aims, Separation And Attitudinal Factors In Mediation: An Exploratory Investigation, Darryl Frank Menaglio

Theses: Doctorates and Masters

The general aim of this research was to explore issues regarding mediation in family law about which there appears to be uncertainty. Study I investigated: (a) what stakeholders (practitioners and separated spouses) believe the aims of mediation should be; (b) what they believe are the effects of the separation factors, that is, perceived mutuality (whether the decision to separate was made by one or both spouses), perceived status (whether spouses view themselves as Ieavers, lefts or neither), and the attribution and strength of blaming someone for the decision to separate on attitudes towards engaging in mediation; and (c) stakeholders' views …

The Effect Of Eccentric Exercise Velocity On Selected Measures Of Muscle Function And Soreness Of The Human Elbow Flexors In Untrained Males And Females, Dale W. Chapman

Theses: Doctorates and Masters

Eccentric contractions, where a muscle is repeatedly lengthened while generating torque, result in decreased muscle function and muscle soreness. This study was designed to determine whether there was a difference in muscle response of the elbow flexors from untrained subjects (n = 12) between a bout of high intensity eccentric exercise at 30°•s-1 (LVE) compared to the equivalent at 210°•s-1 (HVE). Subjects performed 120 seconds of eccentric exercise of the elbow flexors using a Cybex 6000 Isokinetic Dynamometer. At 30°-s-1, a total of 30 repetitions were required whilst at 210°•s-1, 210 contractions were performed (at a 1:7 work/rest ratio). Both …

The Effects Of Dietary Creatine Monohydrate Supplementation And Resistance Training In Older Men, Andrew Lavender

Theses: Doctorates and Masters

In order to ascertain the effects of creatine monohydrate (CrH2O) supplementation on muscle mass and strength in older males, seventeen volunteers aged between sixty and eighty years were allocated to a creatine or a placebo group. Both groups took part in a training programme of the knee flexors and extensors of one leg only, consisting of knee flexion in a standing position and knee extension in a seated position. An adjustable, weighted cuff was used to provide resistance and subjects increased their weight reps and sets at their own discretion. The creatine group supplemented their training with CrH20 starting with …

Development Of An Automated Thiopurine Methyltransferase (Tpmt) Genotyping Assay, Mary Corcoran

Theses

Thiopurine methyltransferase (TPMT) is a cytosolic enzyme that catalyses the S- methylation of aromatic and sulphydryl compounds known as the thiopurines. These therapeutic agents are used in the treatment of acute lymphoblastic leukemia, autoimmune disorders, inflammatory bowel disease and organ transplant recipients.

Erythrocyte TPMT activity is polymorphic and patients with intermediate or deficient TPMT are at significant risk for excessive toxicity after receiving ‘standard’ doses of thiopurine medications. The activity of TPMT is inherited as an autosomal co-dominant trait. Several mutations in the TPMT gene have been described that correlate with a low activity phenotype. Three mutations G238C, G460A and …

Cutaneous Blood Flow In Type 2 Diabetic Individuals After An Acute Bout Of Maximal Exercise, Sheri R. Colberg, Henri K. Parson, D. Robb Holton, Tanja Nunnold, Aaron I. Vinik

Human Movement Studies & Special Education Faculty Publications

OBJECTIVE - We previously demonstrated a positive association between chronic aerobic exercise and dorsal foot skin blood flow during local heating in type 2 diabetic individuals. Thus, we hypothesized that a prior acute bout of maximal exercise would also have positive effects on postexercise blood now.

RESEARCH DESIGN AND METHODS - Subjects consisted of 32 individuals with type 2 diabetes and 26 nondiabetic control subjects further subdivided based on their physical activity status diabetic exerciser (DE), diabetic sedentary (DS), control exerciser (CE), or control sedentary. Dorsal foot cutaneous blood flow was measured noninvasively by continuous laser-Doppler assessment at baseline and …

Microfinance And Households Coping With Hiv/Aids In Zimbabwe: An Exploratory Study, Carolyn Barnes, Erica Keogh, Nontokozo Nemarundwe, Loveness Nyikahadzoi, Ellen Weiss

HIV and AIDS

This study, conducted in Zimbabwe, sought to better understand the relationship between a microfinance program, Zambuko Trust, and how microentrepreneurs’ households cope with the impact of HIV/AIDS. The study examined how HIV/AIDS is affecting Zambuko’s operations and what microfinance institutions (MFIs) can do to lessen the impact of HIV/AIDS on their clients and operations. The findings indicate several small yet important ways that MFI programs help microentrepreneurs and their families respond to these impacts through access to credit and business management training. Participation in a microfinance program led to income smoothing and better financial management, which can help households mitigate …

Age, Temperature, And Parasitaemia Predict Chloroquine Treatment Failure And Anaemia In Children With Uncomplicated Plasmodium Falciparum Malaria, D.H. Hamer, W.B. Macleod, E. Addo-Yobo, C.P Duggan, B. Estrella, W.W. Fawzi, J.K. Konde-Lule, V. Mwanakasale, Zul Premji, F. Sempertegui, F.P. Ssengooba, K. Yeboah-Antwi, J.L. Simon

Pathology, East Africa

The prevalence of chloroquine-resistant Plasmodium falciparum malaria has been increasing in sub-Saharan Africa and parts of South America over the last 2 decades, and has been associated with increased anaemia-associated morbidity and higher mortality rates. Prospectively collected clinical and parasitological data from a multicentre study of 788 children aged 6-59 months with uncomplicated P. falciparum malaria were analysed in order to identify risk factors for chloroquine treatment failure and to assess its impact on anaemia after therapy. The proportion of chloroquine treatment failures (combined early and late treatment failures) was higher in the central-eastern African countries (Tanzania, 53%; Uganda, 80%; …

The Mare Reproductive Loss Syndrome And The Eastern Tent Caterpillar: A Toxicokinetic/Statistical Analysis With Clinical, Epidemiologic, And Mechanistic Implications, Manu Sebastian, Marie G. Gantz, Thomas Tobin, J. Daniel Harkins, Jeffrey M. Bosken, Charlie Hughes, Lenn R. Harrison, William V. Bernard, Dana L. Richter, Terrence D. Fitzgerald

Maxwell H. Gluck Equine Research Center Faculty Publications

During 2001, central Kentucky experienced acute transient epidemics of early and late fetal losses, pericarditis, and unilateral endophthalmitis, collectively referred to as mare reproductive loss syndrome (MRLS). A toxicokinetic/statistical analysis of experimental and field MRLS data was conducted using accelerated failure time (AFT) analysis of abortions following administration of Eastern tent caterpillars (ETCs; 100 or 50 g/day or 100 g of irradiated caterpillars/day) to late-term pregnant mares. In addition, 2001 late-term fetal loss field data were used in the analysis. Experimental data were fitted by AFT analysis at a high (P < .0001) significance. Times to first abortion (“lag time”) and abortion rates were dose dependent. Lag times decreased and abortion rates increased exponentially with dose. Calculated dose × response data curves allow interpretation of abortion data in terms of “intubated ETC equivalents.” Analysis suggested that field exposure to ETCs in 2001 in central Kentucky commenced on approximately April 27, was initially equivalent to approximately 5 g of intubated ETCs/day, and increased to approximately 30 g/day at the outbreak peak. This analysis accounts for many aspects of the epidemiology, clinical presentations, and manifestations of MRLS. It allows quantitative interpretation of experimental and field MRLS data and has implications for the basic mechanisms underlying MRLS. The results support suggestions that MRLS is caused by exposure to or ingestion of ETCs. The results also show that high levels of ETC exposure produce intense, focused outbreaks of MRLS, closely linked in time and place to dispersing ETCs, as occurred in central Kentucky in 2001. With less intense exposure, lag time is longer and abortions tend to spread out over time and may occur out of phase with ETC exposure, obscuring both diagnosis of this syndrome and the role of the caterpillars.

Isovolumetric Regulation In Mammal Cells: Role Of Taurine, B. Ordaz, R. Franco, National University Of Mexico Tuz

School of Veterinary and Biomedical Sciences: Faculty Publications

The ability to regulate cell volume is an ancient conserved trait present in essentially all species through evolution. The maintenance of a constant cell volume is a homeostatic imperative in animal cells. Changes in cell water content affecting the concentration of intracellular messenger molecules impair the complex signaling network, crucial for cell functioning and intercellular communication. Although the renal homeostatic mechanisms exert a precise control of extracellular fluid osmolarity, this is challenged in a variety of pathological situations. The intracellular volume constancy is continuously compromised by the generation of local and transient osmotic microgradients, associated with nutrients uptake, secretion, cytoskeleton …

The Role Of Oxidative Stress In Alzheimer's Disease, Robin Petroze

Kaleidoscope

Over four million individuals in the United States currently suffer from Alzheimer's disease (AD), a devastating disorder of progressive dementia. Within the next several decades, AD is expected to affect over 22 million people globally. AD can only be definitively diagnosed by postmortem examination. Thus, investigation into the specific pathogenesis of neuronal degeneration and death in AD on a biochemical level is essential for both earlier diagnosis and potential treatment and prevention options. Overproduction of amyloid [3-peptide (A[3) in the brain leads to both free radical oxidative stress and toxicity to neurons in AD. My undergraduate biochemical studies with regard …

The Contribution Of Enactments To Structural Family Therapy: A Process Study, Stephanie Fellenberg

Psychology Theses & Dissertations

In an era where the effectiveness of many forms of psychotherapy has been thoroughly examined, the focus of many researchers has shifted from investigating outcome to exploring therapeutic processes. Process studies serve to identify the active ingredients of therapy—that is, those interventions that bring about in-session changes. This process study examines the relationship between the use of enactments, a structural family therapy intervention, and in-session change as observed over the course of the session. Change was measured by the amount of change that occurred in the core problem dynamic, that is, the most prominent pattern of dysfunctional family …

Problem-Based Learning In Allied Health And Medicine, Todd A. Mcloda

Internet Journal of Allied Health Sciences and Practice

This paper reviews the applicability and procedures for the adoption of problem-based learning in allied health and medical education. A summary of PBL as a practical innovation for professional preparatory programs is included as well as an overview of the features and evaluative techniques of PBL. The paper is directed at PBL in health and medicine but those educators seeking to enhance integrative thought processes, problem-solving, creativity, critical thinking, interpersonal communications, and resourcefulness among students are advised to consider PBL as an alternative approach to teaching and content delivery.

Individual Phonological Awareness Training For Speech/Language Impaired First Graders, Sarah Weaver

Masters Theses

The purpose of the present study is to determine the effects of individual phonological awareness and phonics training emphasizing auditory, motoric, and alphabetic properties of phonemes with 3 children who did not make substantial gains following classroom phonological awareness intervention. Subjects were enrolled in the first grade and exhibited speech and/or language impairments. The individual phonological awareness program contained 3 parts: (1) phonological awareness, (2) phoneme-grapheme correspondence, and (3) decoding and spelling and employed a single subject multiple probe baseline across behaviors design. Results indicated that individual treatment was successful for teaching phonological awareness, phoneme-grapheme correspondence, and decoding and spelling. …

The Relationship Between Thigh Muscle Size And 1rm Squat Strength Among Bodybuilders, Powerlifters, And Olympic Weightlifters, James Dinaso

Masters Theses

The purpose of this study was to determine if a significant difference exists in the relationship between measures of muscle size and strength among elite bodybuilders, powerlifters, and Olympic weightlifters. Fifteen male subjects between the ages of 16 and 48 years participated in the study. All three subject groups, Olympic weightlifters (OWL, n=5), powerlifters (PL, n=5), and bodybuilders (BB, n=5), were highly trained and currently involved in competition training. All test subjects were of similar body weight and weighed between 76-96 kilograms. Measures of body weight, body composition (bioelectrical impedence), shoulder width, thigh circumference (proximal, distal, and mid-thigh), and thigh …

Factors Influencing Substance Abuse/Dependence And Treatment Outcome Of Adolescents In A Residential Substance Abuse Program: An Exploratory Study, Melissa L. Moody

Masters Theses

Previous research examining the risk factors associated with alcohol and other drug use has primarily focused on the adult population. Few studies have investigated the factors which influence adolescent substance abuse and the respective effects on treatment outcome. This in spite of the considerable decline in the age-of-onset for problematic substance use that could, if gone untreated, escalate into dependence and a variety of other interpersonal problems which extend across the lifespan. Effective interventions targeting the adolescent population would therefore seem to be of utmost importance to both researchers and clinicians. It has been suggested that individualized treatment programs focusing …